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<entry dataset="TrEMBL" created="2020-12-02" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6T5SDS9</accession>
    <name>A0A6T5SDS9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Histone H2B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_005070</name>
        <name evidence="14" type="ORF">SMAR1040_LOCUS132</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">FE60</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the histone H2B family.</text>
    </comment>
    <dbReference type="EMBL" id="HBFU01000194">
        <property type="protein sequence ID" value="CAD8926185.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6T5SDS9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22910">
        <property type="entry name" value="HFD_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000014">
        <property type="entry name" value="Histone H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000558">
        <property type="entry name" value="Histone_H2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055333">
        <property type="entry name" value="HISTONE_H2B_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23428">
        <property type="entry name" value="HISTONE H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00621">
        <property type="entry name" value="HISTONEH2B"/>
    </dbReference>
    <dbReference type="SMART" id="SM00427">
        <property type="entry name" value="H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00357">
        <property type="entry name" value="HISTONE_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="10 11" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="13">
        <location>
            <begin position="19"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CAD8926185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1744537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="119" mass="12962" checksum="17EBBCFA989F8E27" modified="2020-12-02" version="1">MAKTPSKKAPSKAAKKPTDGAKKRSKKRVESYSTYIYKVLKQVHPDTGISKKGMSIMNSFINDIFERIAGEAGKLATYNKKATLSSREIQTAVRLMLPGELAKHAVSEGTKAVTKFSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1GYV0</accession>
    <name>A0A8K1GYV0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Photosystem II reaction center protein I</fullName>
            <shortName evidence="8">PSII-I</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">PSII 4.8 kDa protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">psbI</name>
        <name evidence="9" type="ORF">QTG54_017182</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="10"/>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2021" name="Front. Plant Sci." volume="0" first="0" last="0">
            <title>Chloroplast Genomes for Five Skeletonema Species: Comparative and Phylogenetic Analysis.</title>
            <authorList>
                <person name="Liu S."/>
                <person name="Xu Q."/>
                <person name="Liu K."/>
                <person name="Zhao Y."/>
                <person name="Chen N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CNS00100</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly. PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">PSII is composed of 1 copy each of membrane proteins PsbA, PsbB, PsbC, PsbD, PsbE, PsbF, PsbH, PsbI, PsbJ, PsbK, PsbL, PsbM, PsbT, PsbX, PsbY, PsbZ, Psb30/Ycf12, at least 3 peripheral proteins of the oxygen-evolving complex and a large number of cofactors. It forms dimeric complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Plastid</location>
            <location evidence="8">Chloroplast thylakoid membrane</location>
            <topology evidence="8">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the PsbI family.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MW679506">
        <property type="protein sequence ID" value="UAM91387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_010200895.1">
        <property type="nucleotide sequence ID" value="NC_058701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1GYV0"/>
    <dbReference type="SMR" id="A0A8K1GYV0"/>
    <dbReference type="GeneID" id="68638022"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009539">
        <property type="term" value="C:photosystem II reaction center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01316">
        <property type="entry name" value="PSII_PsbI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003686">
        <property type="entry name" value="PSII_PsbI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037271">
        <property type="entry name" value="PSII_PsbI_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002735">
        <property type="entry name" value="PRK02655.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35772">
        <property type="entry name" value="PHOTOSYSTEM II REACTION CENTER PROTEIN I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35772:SF1">
        <property type="entry name" value="PHOTOSYSTEM II REACTION CENTER PROTEIN I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02532">
        <property type="entry name" value="PsbI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161041">
        <property type="entry name" value="Photosystem II reaction center protein I, PsbI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="10" id="KW-0934">Plastid</keyword>
    <keyword evidence="2 8" id="KW-0674">Reaction center</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1732139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UAM91387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="38" mass="4451" checksum="DBA95EB155CC67B1" modified="2022-08-03" version="1">MLTLKILVYTTVIFFVSLFIFGFLSSDPSRNPNRRDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSG7</accession>
    <name>A0AAD8XSG7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Circumsporozoite protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_016515</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Essential sporozoite protein. In the mosquito vector, required for sporozoite development in the oocyst, migration through the vector hemolymph and entry into the vector salivary glands. In the vertebrate host, required for sporozoite migration through the host dermis and infection of host hepatocytes. Binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes.</text>
    </comment>
    <comment type="function">
        <text evidence="5">In the vertebrate host, binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes and is required for sporozoite invasion of the host hepatocytes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the plasmodium circumsporozoite protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000057">
        <property type="protein sequence ID" value="KAK1732803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSG7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051860">
        <property type="entry name" value="Plasmodium_CSP_Invasion"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44826">
        <property type="entry name" value="SPORE COAT PROTEIN SP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44826:SF3">
        <property type="entry name" value="SPORE COAT PROTEIN SP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0748">Sporozoite</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042054954" description="Circumsporozoite protein" evidence="9">
        <location>
            <begin position="20"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="304"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="406"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="20"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="78"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="144"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="41"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="78"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="98"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="144"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00033726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00045806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1732803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="457" mass="48394" checksum="AF206728A02E7D85" modified="2024-05-29" version="1">MNFVVAVAFFATHFHTSSASENERSWGWGGGGKPTNKPTRRPTSNTWTWGSSPWSNNGPTNWVWNGWGWNEDVSHNAWTGDGWNGNWNGKQTSAPTGTPTSFPSDSPSISIAPSSFPSYSPSTTVSPSSFPSYSPSTTVSPSSFPSYSPSTTVSVSPSSSPSDSPSIAPSSFPSNSPSISIAPSSFPSNSPSSLPSVSTAPSSTPSTSSLPSVSTAPSSMPSISLQPSLSSQPTLDSCVPDDEAVADAACRNTTGTIGDQSCRGVNACINSKAMLDRDHVMMRAEFLMVEFVKAVKAPILEMTVVVAESLVIITKVILVMRVALIILRATKTQVILKMEAVKVANHVSIILARLKEVAATATERVTVILKMEIILARLKEVAATATERVTKQLAQKARIAAMGNSLVVDLLAMYILTLATVTLHAATQPILGVTVLEQASLVYHPSLLSLNPKKREI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSI2</accession>
    <name>A0AAD8XSI2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cGMP-dependent protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">QTG54_016671</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.12"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.12" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000062">
        <property type="protein sequence ID" value="KAK1732610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSI2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030553">
        <property type="term" value="F:cGMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004692">
        <property type="term" value="F:cGMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF143">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0140">cGMP</keyword>
    <keyword evidence="9" id="KW-0142">cGMP-binding</keyword>
    <keyword evidence="7 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="15">
        <location>
            <begin position="259"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="15">
        <location>
            <begin position="493"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="15">
        <location>
            <begin position="562"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="15">
        <location>
            <begin position="689"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="820"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="16">
        <location>
            <begin position="1081"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="49"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="177"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="334"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="418"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1130"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="68"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="178"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="195"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="334"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="423"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="438"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1130"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="859"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1732610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1150" mass="126798" checksum="E5F273B8D2B37760" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSQ8</accession>
    <name>A0AAD8XSQ8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_016353</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000055">
        <property type="protein sequence ID" value="KAK1733022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSQ8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="71" mass="8148" checksum="0E653CD622923D24" modified="2024-05-29" version="1">MHSHSCRQLHWPHKTTDIKPKTTLLQWASTTTMIGRSFQLKFNKPLPLSDTTRVFGIKMTNPTHAMSTGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
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    <name>A0AAD8XSR4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="1 2">
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        <dbReference type="NCBI Taxonomy" id="267567"/>
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            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
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    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="protein sequence ID" value="KAK1732730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSR4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1732730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="80" mass="8855" checksum="873A11CE59A8D131" modified="2024-05-29" version="1">MGQGSNYAVVKDAQINLIEEEFTGDMEQRRNYAALKDAQINLIQEECVGDMGRRGSFAVVKDTNQSYTGGVCIRHGTKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSV4</accession>
    <name>A0AAD8XSV4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016081</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
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            <taxon>Sar</taxon>
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            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
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    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000052">
        <property type="protein sequence ID" value="KAK1733224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSV4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="198"/>
        </location>
    </feature>
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    </feature>
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            <end position="294"/>
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    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
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            <end position="310"/>
        </location>
    </feature>
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    </feature>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="428" mass="43488" checksum="3B1E353200524AEC" modified="2024-05-29" version="1">MAVASFNDSHRSTAVLNTAAPSDAEGQETDLATYHSSSYDEGYDAAAGAATFGDDEAAVAGGGGIWSRRNKLLMSLIAGSAFLCAVSTGGAAAYKAHMANANSISKCFIDELDLVAVSSGASSKASKSPNRRDLIEATVDEEAIMSTGAYYPDAPKMVEDKRADRMGEGKTQYVRGLSSGSSSKSTKSPSSSSKAGKAVNSMPLEIPCDCVQYYSSSSSAKASKAAGASAKASKAAGVSGSGKATKSPTTSSAKSAKSTPPTMPPSCMLPPVGSKSAKSSTVPGSKSSKSSTAPLPAPLPAPLPAAPTPEPSIRKEEIITSKPTTAPTTAAPTPKPTPIIPVPIEFPTGFPKVKTDSPTYGSTVTVGDEATTAPTPIREEITTFSPTSVATDVATPGVTVTVSTETTGPPTTTLRVEDADKKKKKDNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSX3</accession>
    <name>A0AAD8XSX3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016532</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
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            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
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                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000057">
        <property type="protein sequence ID" value="KAK1732820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </feature>
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        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSZ1</accession>
    <name>A0AAD8XSZ1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016523</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000057">
        <property type="protein sequence ID" value="KAK1732811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSZ1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="166" mass="18692" checksum="7E8775FA96B2113A" modified="2024-05-29" version="1">MVAGNRNSNKYAAPKGDDITTFTIMVPTDNTLNPADREIDLRQMDEQDLKSLQKSDPFMYYSIPGLRQASLRHNDVDYSDIASLSRAVSLPSSPSRSRPSQAQEEGEGDACKVSRRTCISFECHPDVLMEDLMDEMVQELGDLSIDYDDFLSIFGRRSTMPRSTKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTW7</accession>
    <name>A0AAD8XTW7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ferric reductase-like transmembrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_015927</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000050">
        <property type="protein sequence ID" value="KAK1733368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTW7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF193">
        <property type="entry name" value="FAD-BINDING FR-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="275"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="595"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="636"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="domain" description="Ferric oxidoreductase" evidence="8">
        <location>
            <begin position="158"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="Ferric reductase NAD binding" evidence="9">
        <location>
            <begin position="466"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="716"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="719"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1733368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="808" mass="90057" checksum="575DB6287A44DF04" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XU05</accession>
    <name>A0AAD8XU05_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XU05"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="26" mass="2931" checksum="1BE0F82876B4D17B" modified="2024-05-29" version="1">MASRSSLQTRNDSLVRFFPNTSVGPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XU14</accession>
    <name>A0AAD8XU14_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000049">
        <property type="protein sequence ID" value="KAK1733460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XU14"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="157" mass="17355" checksum="C0F5AD7E25EB9D4A" modified="2024-05-29" version="1">MSSCCSPTGEEMSNQTTFLDTFKSGSKRFATLVADTGAKTMLKTDVAFLERDIKNRKHTFGIQIYEILQSNTKSSSTSDTVFSASDDIQTAFEECKLDVETLEKKIEKKREEMVNIGDGQQQQQPQQQQQQHDEGGGDGESVSGRNAELESGILPGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVL1</accession>
    <name>A0AAD8XVL1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000040">
        <property type="protein sequence ID" value="KAK1734253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVL1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="455" mass="51090" checksum="AF926E0A0E6970E2" modified="2024-05-29" version="1">MRFSILPRVFSSRQAAKKQNTNKPADNTSNEDGSATTDDESSTSSNTSTNGNNKSISTNSTSSKSFPRKKYPLLSSSTSPSTVPSKALPVRIQFALSMFMQRPIPQNWSYLVSLLRGENMQRRLEEPSLSSSWPRSQNNHDEGAKRTLARLEKSLADELTVYEEEVDDEESLEEEREESTVEGETVMELLAPNALSLVNSSAGRQHSDEAEIDVPGSVAKTFIKRPSAENWDLLVQLFRNENRQRWDKDQPHEIMRVESDLTCDESLDAMERNNPKALSIIYESDEETDHDNEDDGEEESIVGIGLLPEMYNESDESEGVEDEEQKDELVIEKEEDDEDNDLEREIRATEESSESPSACQVDWPCSEEEETTAEAEEVAAVPSRAFLRPAPKATTRVPPSFANTRAKAYVLLWERRIRRFDQSQVNVVQKSVQPANVVQSTDLSMAPKAKCLALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVR1</accession>
    <name>A0AAD8XVR1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lipoxygenase</fullName>
            <ecNumber evidence="6">1.13.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_014727</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000038">
        <property type="protein sequence ID" value="KAK1734479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVR1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034440">
        <property type="term" value="P:lipid oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.245.10">
        <property type="entry name" value="Lipoxygenase-1, Domain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000907">
        <property type="entry name" value="LipOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013819">
        <property type="entry name" value="LipOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036226">
        <property type="entry name" value="LipOase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11771">
        <property type="entry name" value="LIPOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00305">
        <property type="entry name" value="Lipoxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48484">
        <property type="entry name" value="Lipoxigenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51393">
        <property type="entry name" value="LIPOXYGENASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042069820" evidence="4">
        <location>
            <begin position="24"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoxygenase" evidence="5">
        <location>
            <begin position="82"/>
            <end position="690"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1734479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="690" mass="78358" checksum="F8DFE036F0D1BC81" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWD1</accession>
    <name>A0AAD8XWD1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWD1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="308" mass="34184" checksum="C673C03A697F3FA6" modified="2024-05-29" version="1">MPDDKKIVESEIYNRFSAIVKEKFTSLSNDGSKINQLDDLDELYKRPEFSAEKQILNEMNSIGLSKGILTGLACFAFLRTSPRLISNYMRRRAGSSGADINSGAPNPFQQKASGSGYKFDSSLNNQNVERPGLLFRGVRLLLDSFVSLSIGAYASIFFTDTTKMMEKFSTVPLVEGRSLLSEQLCGDFSQEFQKYDRQIWNSNHPSLTGGDVSGEDIDGFRELIQGFVVNCKRREIYEKEIRAEQGLGADDPVIIPTPGVPRDISVTMDDLLSSTESGDNNAHATDGGDEFFDTYFDSADDEGDYQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXF6</accession>
    <name>A0AAD8XXF6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF1971 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014271</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXF6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015392">
        <property type="entry name" value="TehB/YeaR-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09313">
        <property type="entry name" value="TehB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041986177" evidence="1">
        <location>
            <begin position="24"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="TehB/YeaR-like" evidence="2">
        <location>
            <begin position="94"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="187" mass="20756" checksum="18EF136AB910864E" modified="2024-05-29" version="1">MKFQSTLLPLAYTFAMLGGTAHAFIQSKNIIRKPCNRTTQLLSSNTLQYRTRAVPSLFLASSDDSSSDANRRQANGMAILPSNVVKYSTVPKDKFFTIDTIPTGLLKEHSTKEGTWGVIRVHQGKLEYTILEPEQSVHILDAESDNVGIIEPTMLHQTKGLTDDLKFVVEFCRVPGTGDVDEQREGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXL0</accession>
    <name>A0AAD8XXL0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Gamma carbonic anhydrase</fullName>
            <ecNumber evidence="3">4.2.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013647</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Luc7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXL0"/>
    <dbReference type="SMR" id="A0AAD8XXL0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006376">
        <property type="term" value="P:mRNA splice site recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04645">
        <property type="entry name" value="LbH_gamma_CA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047324">
        <property type="entry name" value="LbH_gamma_CA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004882">
        <property type="entry name" value="Luc7-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050484">
        <property type="entry name" value="Transf_Hexapept/Carb_Anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13061">
        <property type="entry name" value="DYNACTIN SUBUNIT P25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13061:SF29">
        <property type="entry name" value="GAMMA CARBONIC ANHYDRASE-LIKE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03194">
        <property type="entry name" value="LUC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="320"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="555"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="691"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="394"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="555"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="716"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="746"/>
            <end position="775"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="775" mass="84747" checksum="B43CAAEF53B4144F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXP3</accession>
    <name>A0AAD8XXP3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013954</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXP3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="119"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="135" mass="14473" checksum="88B8DD4734A4A0ED" modified="2024-05-29" version="1">MSSSKETPAASVVSALFSSDDTSLAEGFRDKVAALHSFFDRDKDGFLNHSELRGLQLLTSGEEMNVPTYLMACRSIGCDPQQGISLDGLRLVYAAEGSNVEDDYSKVFPAKGEAKASDKEDDVLEVGEDGVDIST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXR8</accession>
    <name>A0AAD8XXR8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sel1-like repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXR8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="240" mass="26611" checksum="71644D07A890A52D" modified="2024-05-29" version="1">MGDCPICLLPLPFDGLQYTLFPCCSKTICNGCDYAIETNEKKSGSKHTCPFCRHPVAETVEEAKRDIKKRVEKNDRVAIRQMGLGLRKEGNYDGAFEYLSQAADLDDIEAHYQLSIMYQKGEGVEKDEQKEVHHLEKAAIAGHPKARHNLGCIEGNNGMQKRAMKHLLISASLGDDLSLEELRIEYATGRGHVSKENFAAALRAHQAAVDAMKSPQRDEVQIVGGPTWAWVRTGDSETLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XY96</accession>
    <name>A0AAD8XY96_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rossmann-fold NAD(P)-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XY96"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051207">
        <property type="entry name" value="ComplexI_NDUFA9_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126:SF16">
        <property type="entry name" value="MIOREX COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="1">
        <location>
            <begin position="16"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="250" mass="26790" checksum="0DF9C59958122E65" modified="2024-05-29" version="1">MAQASNTIKKSLLVLGGNGYVGQNVLHAAIQSNLFSEVRSFNRSGSPKSPPPHLAESLSQVEFLTGDIFDNSAREDAIDGNYAVVSCIGAFGSNDFMKKICGDATIEAIETSKQKGVNKFGFVSSAQVYEGSAGLKIPPSMPMHGYFQGKYNAEQKLLESYPDGHVILRPGFIYGRRNVGSVQLPLQLIGAPINIVGNHLGPISSLIQSVPFVGKEVSSMVPVESVGRSMIDSLKEEKGVILEAADIRQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYL9</accession>
    <name>A0AAD8XYL9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012899</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="entry name" value="Intergrase catalytic core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052055">
        <property type="entry name" value="Hepadnavirus_pol/RT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33050">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33050:SF7">
        <property type="entry name" value="RIBONUCLEASE H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1699" mass="188292" checksum="0723400041C62A5C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZ52</accession>
    <name>A0AAD8XZ52_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dynamin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZ52"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056024">
        <property type="entry name" value="DUF7605"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36681">
        <property type="entry name" value="NUCLEAR GTPASE, GERMINAL CENTER-ASSOCIATED, TANDEM DUPLICATE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36681:SF3">
        <property type="entry name" value="NUCLEAR GTPASE, GERMINAL CENTER-ASSOCIATED, TANDEM DUPLICATE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24564">
        <property type="entry name" value="DUF7605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7605" evidence="1">
        <location>
            <begin position="137"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="503" mass="55351" checksum="A13BC9ED2DD4F07A" modified="2024-05-29" version="1">MKIKPSRDGPPSCFSNAEDTQIPLLRAFVHTTTAKHCQDSVKTFVEQTNDLVEQMKLLCTDSNSDVSTGSARRMKQLHKSSVQSLTNQIKPIATQFKQVIDQKVSNSLASSLKTGARKGSQSAISTVVSWGSKSRRSKSERAPDKNGLYYSTYNAVARRDGVYTSKSAGAVDFNQELCDPMEKEFSTEWQSVLDSTIRRLLAESERKILDLSTSACQSFAQSLRSNGVAADRLGNMLNTANRSATTALKTSFTQMRSIARDAQRELSRELLPAVQEKMKSSYTAVKSAQGGPGVFERMKGAMVSNSQRAVNEMFDSAMDKLMRGIKALINRLERLLESTATIVGKSLENVFSICWDDNSDKTTLIDPQMQKLIQDCRNALLPELNRLQTIQGDACELLGIEREEVELDLVGVESLEQQLSRRVAEAEKNGNMLDLCDSDADVPAPKKMAVKSEKGAVIRKKSPLKTSAAGVIDLCDSDSDEDEEGNIFGKCPSTVNVKTEAWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZE4</accession>
    <name>A0AAD8XZE4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CWF21 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_012768</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZE4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21372">
        <property type="entry name" value="cwf21_CWC21-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051372">
        <property type="entry name" value="CWC21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013170">
        <property type="entry name" value="mRNA_splic_Cwf21_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36562">
        <property type="entry name" value="SERINE/ARGININE REPETITIVE MATRIX 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36562:SF5">
        <property type="entry name" value="SERINE_ARGININE REPETITIVE MATRIX 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08312">
        <property type="entry name" value="cwf21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="CWF21" evidence="8">
        <location>
            <begin position="89"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="16"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="125"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="40"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="125"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="137"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="180"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="191"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="229"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="302"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="315"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="359"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="400"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="437"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="462"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="519"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="558"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="569"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="621"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1736746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="652" mass="73754" checksum="AB57F51D55610176" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0B0</accession>
    <name>A0AAD8Y0B0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012248</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0B0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="509" mass="56311" checksum="3A6AB60F6E3D1E4E" modified="2024-05-29" version="1">MSPSSGPGESTIVRLVPSTLLVIPRALDMSRYLLGIGEKPQTKNFFIRLFTDFGLKSVKSRPTFVDPRLSCQPTSIATPTPCAALSCLLPPSLSPCYRCDGQWRWRSEGLSINGGVCVRHEAKRKLCSSGGCTNKVIEGGVCRKHGAKVKRCSSEGINNGVCVKHGAKIKRCSTEGCTNKAQKGGVCYRHRAKAKRCSSDGCTNQSRKGGVCIRHGAKIKRCSPEGCTNNAQKGGVCRGGVCVRHGARAKRCSSEGCTNVSVKGGVCKRHGAISIVNVKLYNSEGANQVQRGGVCWRHGANRITHNESTAFGSEFEKTTATRTSPNQRAPRAAAREGQEGSRVFQEVAILCQDIIEWLCEFEKTTATQTPPNQLLQLPQEKDRKEVEFFKRLPFFVKKLLNDSNADCRFCIPTFITESEAERRSPSSQYFLYPVNIALQEKVDVKLLWAFRFDTDRASSFFSRSILMVSYFAPRHAYGHYYCQNPQSCALLRQDQARLNNASRFMMLTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0G8</accession>
    <name>A0AAD8Y0G8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MINDY deubiquitinase</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012338</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0G8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016807">
        <property type="term" value="F:cysteine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990380">
        <property type="term" value="F:K48-linked deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071108">
        <property type="term" value="P:protein K48-linked deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007518">
        <property type="entry name" value="MINDY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033979">
        <property type="entry name" value="MINDY_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18063">
        <property type="entry name" value="NF-E2 INDUCIBLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18063:SF6">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04424">
        <property type="entry name" value="MINDY_DUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MINDY deubiquitinase" evidence="2">
        <location>
            <begin position="2"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="526"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="526"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="567" mass="62659" checksum="BDFFC02F72D3B846" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0V9</accession>
    <name>A0AAD8Y0V9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Homocysteine S-methyltransferase family protein</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_012417</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0V9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.330">
        <property type="entry name" value="Homocysteine-binding-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003726">
        <property type="entry name" value="HCY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036589">
        <property type="entry name" value="HCY_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11103">
        <property type="entry name" value="SLR1189 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11103:SF18">
        <property type="entry name" value="SLR1189 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02574">
        <property type="entry name" value="S-methyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82282">
        <property type="entry name" value="Homocysteine S-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50970">
        <property type="entry name" value="HCY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Hcy-binding" evidence="4">
        <location>
            <begin position="1"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1736972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="359" mass="39680" checksum="EBA6AF9DDFB3A607" modified="2024-05-29" version="1" fragment="single">LRSSPNQTLLLDGGTGEELFLRGVKDDRKIWSATAIVNEEYHGILEEVHKSFIDAGSQAITTNSYGITPGVGFTDGDEVKRLVGISGEIASRTATDQALVLGSLGPQVESYRPDLIMKHDEGVQTYQYPIEGLYPFVDIYLAETMSVLEEAFQVVDALSIFYQTQTQGELAKHPLLISFTLRSDGKVRSGESVSEVIPLLIQRAYEKKVELIGVLFNCCEPEAITKALQEIRSCSDIHHHLYHPPLLSKRCATTSLSEQTPISQPPKIFLGAYANRLTPVHEEWTLESSEEAQAMREDLLPDEYWKEFVDRWHGNKDDGVAAGISNISLIGGCCGIGPSHISFLSSKLNISNNNNNNNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y155</accession>
    <name>A0AAD8Y155_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012022</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y155"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="243" mass="26410" checksum="7E6AFD3A4EB81992" modified="2024-05-29" version="1">MRLYSSSLLPAAFLTPNGPVRISQLSLHPRRCRPSSSQLYGDPSYGLTDDGDFAILGVNAYDNSDDDNSSMGQSVGGLSSILSGVGLSEVTTQPSGPESTNTAISRNNNMPNFGSTTSSINDAIFGRLDSSSMMGIPDAKKGSVIGENVGERSTDTQQQNQYTRSSDVDETTLFEIQEWLFSIIPALNEQDAESYSRGLDAIGFNPGCVTMCELQIEDLGFMKVLHRRYLFNEVTGNEHPWEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1A0</accession>
    <name>A0AAD8Y1A0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_011853</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1A0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052420">
        <property type="entry name" value="Espin/Espin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153">
        <property type="entry name" value="ESPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153:SF8">
        <property type="entry name" value="FORKED, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="534"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="311"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="542"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="557"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1737567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="581" mass="63981" checksum="AF30FA85434C779C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1J4</accession>
    <name>A0AAD8Y1J4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Synaptobrevin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_012199</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endomembrane system</location>
            <topology evidence="3">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the synaptobrevin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1J4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd15843">
        <property type="entry name" value="R-SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.50">
        <property type="entry name" value="Longin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010908">
        <property type="entry name" value="Longin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051097">
        <property type="entry name" value="Synaptobrevin-like_transport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21136">
        <property type="entry name" value="SNARE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21136:SF168">
        <property type="entry name" value="VESICLE-ASSOCIATED MEMBRANE PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13774">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00957">
        <property type="entry name" value="Synaptobrevin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50859">
        <property type="entry name" value="LONGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="257"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Longin" evidence="6">
        <location>
            <begin position="113"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="7">
        <location>
            <begin position="196"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00046280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1737332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="291" mass="32955" checksum="ED86EAC8D5134791" modified="2024-05-29" version="1">MILYALVARSKDGTILVEQTIAGVSGGNFPQISIEVLQKVVSTSNYNSAVLGTLESAASDEMLPNGTRRTFVQRHGSGSGFFSGLATQWSYYGNNDDDGNTNNNSAQGNGELDYYFHMYRNEDIITLCISDDTDARYHNVNYSFLDDVDQEFIKNYSAYKITKAKAYEFDKKFKITMGKLLHFYNENRSKMVRQGKLADYIQRVDDVKDILGRNITLVMDRGESLQDLVQKSDDMLQDVQVFSKRSSQLKRRVQTEYYSYQCMAVAFVVLVLYLAVGSLCGYGFQCVWSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1Z4</accession>
    <name>A0AAD8Y1Z4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011843</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1Z4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23534:SF1">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23534">
        <property type="entry name" value="MFS PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="363"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="413" mass="44012" checksum="E62C10B3CF6272B7" modified="2024-05-29" version="1">MAPPTWTSSTATTTRSRSNMIKNVLLLAGMWGMGLGAAFVQLPATQNLLIDAGYASISTAPLGIIMLGSAPCAVVIPKIISRYGEKKTFIAGSFFGIVGAIMQMIGPLTTTIGLAAENDVTPQVVLVVIGALPQAFMYASTNNLRFSVSQFSTPAFLPKATALVLLGGVLSALLGPLLSAQPMADSDDVRIVVDDLSLVERQEITAAGEGTRIDGNATTERALWEIIKGTDLPLLTTFQCLSYNIMAMYMGQLKLPMAASGYSVINQFGTWSTTAVGFLLFPVGGSMFLINDSLAMFVLGITIVGIGWNFSFVGPSAEVSKICSRAEQSKVVGFNDGIMLLTVGIFFMTASKIYIAVGSWNVFNYILIGFSVFSALLSLLRWYANGELQMEMITVFPEIRCQSLLTAGSICTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2Y1</accession>
    <name>A0AAD8Y2Y1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011136</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2Y1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="710"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="734"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="757"/>
            <end position="791"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="840" mass="94622" checksum="C1DD5CA4CDF931F1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y304</accession>
    <name>A0AAD8Y304_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-directed RNA polymerase II subunit RPB4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_010741</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic RPB4 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y304"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006590">
        <property type="entry name" value="RNA_pol_Rpb4/RPC9_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045222">
        <property type="entry name" value="Rpb4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005574">
        <property type="entry name" value="Rpb4/RPC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038324">
        <property type="entry name" value="Rpb4/RPC9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21297">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03874">
        <property type="entry name" value="RNA_pol_Rpb4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00657">
        <property type="entry name" value="RPOL4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="HRDC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb4/RPC9 core" evidence="4">
        <location>
            <begin position="29"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1738711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="171" mass="18889" checksum="17B292EFDDA9B910" modified="2024-05-29" version="1">MAESNRTPSAAATSAVAKVENTAELSFGTEFDDAEINILSNAQVAVILQMSAQSALIRDEELDDVYKKTQKYVERFNNMKNPEKDNQELVSELDNLHGALETFRKEKEDGEEMALHGFEVAALMNLVATDTMVEEAQALIPSLSRFPESAVDEILDLIRSTMIRIVSYGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4L1</accession>
    <name>A0AAD8Y4L1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Chlorophyll a-b binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_010280</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated. Energy is transferred from the carotenoid and chlorophyll C (or B) to chlorophyll A and the photosynthetic reaction centers where it is used to synthesize ATP and reducing power.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fucoxanthin chlorophyll protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4L1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030076">
        <property type="term" value="C:light-harvesting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="8" id="KW-0157">Chromophore</keyword>
    <keyword evidence="7" id="KW-0437">Light-harvesting polypeptide</keyword>
    <keyword evidence="5" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042017897" evidence="9">
        <location>
            <begin position="16"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1738964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="213" mass="22394" checksum="6AB647C0B05B1430" modified="2024-05-29" version="1">MKLAVISTLIAGAAAFAPAPVANSGSALSATRAVKDAPAKGKAKNISFGEGNVNPTGLIGDLPPVGFFDPAGFAAKASPEKLIRYLMHGRFAQLAILGFLLPEKYAAEGAFGDDFLAPTGTALEVFNTDPLWVGLTLAVISCLETIRLLQTEPGTRTDAKILEVGLYPEQSPEKLAEYSLKELQNGRLAMLAFAGAVVQELVNETPLILNLQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5N1</accession>
    <name>A0AAD8Y5N1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009043</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5N1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042196434" evidence="1">
        <location>
            <begin position="22"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="356" mass="39311" checksum="54F5EC8DEC6AEF23" modified="2024-05-29" version="1">MRLLIAYALSAVLFICNDATAFSTQRLSNKHARQPTTQLMMTQHISRRRLMISTISSISASAGLSQSALAAPPLSAEEADNFQARFERGLRSKPARVLRQRMNIDFAVLLMRSSYNAVDELDIVAMDQFQKDFFLIRQAEYQYYSDSIGAGAMQQGDLADPNYFDFISFAQYATISREIVNPPAVFEEQQPVEVGEEQPQKFDAVVVRRDPAIKNSDLPRIHTEIVGNAILDKLIEKFGETASAIPTIEPGSRPDAVTFLAAIKQMVNLFTLSGFAWEGGASMVQGSSIKDTQFSIIFTSPATLWSGQSLAAKKAVLSNDFALKTVKAMATRAGYKVVNDSVKYKGNQEITTFSVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6I9</accession>
    <name>A0AAD8Y6I9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter, ABC-G family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_009716</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6I9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="13"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="406"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="439"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="496"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="528"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="557"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="627"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="123"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="46"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1739957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="656" mass="71910" checksum="8F2DD2E9F490AE84" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6J3</accession>
    <name>A0AAD8Y6J3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008756</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6J3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="74"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="207"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="318"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="515" mass="59133" checksum="29D615F9AD932081" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6P6</accession>
    <name>A0AAD8Y6P6_9STRA</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008834</name>
    </gene>
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        <name type="scientific">Skeletonema marinoi</name>
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            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
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                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6P6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="253"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="279"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="326"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="501"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="603" mass="66984" checksum="1A0D9D976EFE3C6E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7T8</accession>
    <name>A0AAD8Y7T8_9STRA</name>
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        <submittedName>
            <fullName evidence="4">Nucleotide-diphospho-sugar transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_008745</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
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            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="AlphaFoldDB" id="A0AAD8Y7T8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005069">
        <property type="entry name" value="Nucl-diP-sugar_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052636">
        <property type="entry name" value="UDP-D-xylose:L-fucose_XylT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47032">
        <property type="entry name" value="UDP-D-XYLOSE:L-FUCOSE ALPHA-1,3-D-XYLOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47032:SF1">
        <property type="entry name" value="UDP-D-XYLOSE:L-FUCOSE ALPHA-1,3-D-XYLOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03407">
        <property type="entry name" value="Nucleotid_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleotide-diphospho-sugar transferase" evidence="3">
        <location>
            <begin position="330"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="73"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1740650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="616" mass="69570" checksum="F523E9CF75A7C773" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7W0</accession>
    <name>A0AAD8Y7W0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nucleotide-sugar transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_008724</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7W0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015165">
        <property type="term" value="F:pyrimidine nucleotide-sugar transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007271">
        <property type="entry name" value="Nuc_sug_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10231">
        <property type="entry name" value="NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04142">
        <property type="entry name" value="Nuc_sug_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="200"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1740629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="390" mass="41071" checksum="B2AD080A008F4459" modified="2024-05-29" version="1" fragment="single">MTLLGSHTPAAAFAGVRTLTNSHRSLQILTKNAPYALPSLVPNSAARIASNTALNSLNPIALLGGAAQDTLGPAAICTMALLAVQYCAQPPLTRKFLDSRVNKKGITMVEEICKMGLSAMFFMSMGKDVVASSLKGWTLQSSLLLAGLPAVLYATQGVLTYLGYQHTDSVTFNGLNQTKTLSAALWCYLLMGMRQSPVQIVALGVLVFSALLFQGTISFSSLFGKSDDKSKDAKGGEKKQTSLSKGILPCLGAAAISGLAGALSQKGVQVAGGSGRNPYLYTMELGLYSCCSLIVSIFATKNGRKALREEGGIFKHWTPMSLIPIVVRALGGVLTALVHKYAGATRKGYALIAGLIMTGLTQSVIEGERLSSNEILAVVFVILSSYLHLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y854</accession>
    <name>A0AAD8Y854_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007876</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y854"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010756">
        <property type="entry name" value="Tls1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07052">
        <property type="entry name" value="Hep_59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="311"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="453" mass="48923" checksum="150CB6C6F8B6DDAD" modified="2024-05-29" version="1">MADTQQQPKIKFKKRNIKKKQLRKADPTADDVAATDSENNSNDAIKDNDNEEEEEGALTAILAVDRRRKLFNNRNRGVDSAHLLKPTKSTKTTGDETTTTVDTNKNKDLEERLKGNFSEGKLAGSNDMGGDEEGGLLAKKHRRAMEDFIQQNLQGGGGGVTAQSNGEDATDGNGGGGGGPTEDEKEMFAELLQSDSTNTSNNPANGSQSKEGDVGAGGAMMMGSGIAEVALPAAERLRTLKETEKAAMEYEKAHRRVKPQHDGGNADATDDNVHDLVPMNFASGPGKRKRQEDADMGSSTAATISTSPNKSATSQNNEQSTTTSSSAAYSASSAGGSVQRSDVSTLGQSYSHNFQLHQQDWIAQRRDERQVEIDTLKTQQQAEEADDIGGVSGERMGFQMARRAAKGESVRPAPARGPNGESLKNEWDRTKKGGNQRSNDDRVWKQFMKKTKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8A4</accession>
    <name>A0AAD8Y8A4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008907</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8A4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046345">
        <property type="entry name" value="TraB_PrgY-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21530">
        <property type="entry name" value="PHEROMONE SHUTDOWN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21530:SF7">
        <property type="entry name" value="TRAB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="427" mass="47420" checksum="DF76F3274E7BC8BB" modified="2024-05-29" version="1">MKSNESENFFGETLRFSERFSKFSINKSENRSLAKFDECQPQVPMIPPSPITRHLVKIHHHTPTAPTLRYRNDINFSSSRIMMNRLLPITVALATLHGVCDAFVTNRPGGFHAVKSYPTNSKLRSQILDFIEPSTGVQVKLIGAMHYNPASIQLATDTINQLEKEGKLGSIIIESCDIRWNATLENEFVQDQLMSEMRAAHDLGLLYERPVVLGDQRINITVSQLKNGAKEAVLDLVQPWNGGWNRLYDSVSTARKEAIPMGEGFLGIDSFFDPKLMTAAPVSLLKYPLSYFVRSPVFSIIVLCFFILSGGVDDANALSDLTPTDLAESIFFSALETVIFARIFLKELLAERNEILAENIFEQCRNYAADKGNVWDKLFQPAGDKSKGAIYAPDSVVGNSAEEGKVVVAVLGLAHCNGIKKIMTEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9Q3</accession>
    <name>A0AAD8Y9Q3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-dependent Clp protease ATP-binding subunit ClpX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007839</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9Q3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050052">
        <property type="entry name" value="ATP-dep_Clp_protease_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102:SF7">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="344" mass="38041" checksum="3C1397428DACF72F" modified="2024-05-29" version="1">MMRPSLALRNSRRLNVRHLHRCCRTEQQQCAPLALLNNRHNDATSKRMIHIQPLPMPAVAHCDFDVYDDIDDYEYGDDNDNAHQASHVDIVASAAGGNSGRGPTMMGGNNHNNDNTTSSRFVGGGPPNGGGGGHSHHRCPKCGASVTFQDSSKNKGMQNNCFYCAACSGWFLVKPTNSEMDESKFLLSKMAAAAEGNGEKVVGAPGNRKISQPQFVMQHMPEQSNSRNTTDPRVSNIPRRPTSIDQQQLNNDPDLQERITRHRATPNPLLSGNSNSGYPPPPPQQRLPTPREIFDGLNEYVIGQRNVKVALSVGVHNHYKRIIVVRRKRRHCRRCSGNNQGDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9W1</accession>
    <name>A0AAD8Y9W1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_007273</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9W1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050441">
        <property type="entry name" value="RBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48034">
        <property type="entry name" value="TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="222"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="306"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="87"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="123"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="155"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="173"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="313"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1741700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="359" mass="39344" checksum="6F01F28DCB5CEF70" modified="2024-05-29" version="1">MPPSSSPPPEGSPPRESESDMNNQNSSGPPPPGGASEPEERDRSRSRSRGSGSRGSRSRRSGDRDDRDRRDRRRGGGGGVGGVSSRSRSRSRDRSRRRSRSRSRSYDRRRSRSPRSRSYSRSRSHDRGGRGRDRDRRHRRDFRDRDRHGGPPPHGGGGGGGPRGAGHYDDRYGPPPPGFFGGPPPGPGGVPPHGFPGDFPPPNAGNRRGGRASRRDDGPPGVSLLVRNVSPDISTQDLTLAFGRIGEVRDVYIPRDYHSQQPKGFAFIEYATPEMAREARDEMDKFLMKGRELEVVYAQEKRKTAVEMRGRVVDGGGGGGGSQRRGRGGGGGGGGGGDFERSSSFERHKRRERERESYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9X6</accession>
    <name>A0AAD8Y9X6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cyclin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9X6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000093">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0195">Cyclin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="2">
        <location>
            <begin position="61"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="287" mass="32533" checksum="002D86D3CC871DE8" modified="2024-05-29" version="1">MSSRSIAKAADVLDRWYNLLEQEANAYKTANYLTTPSQTNDKGNTFDTDTKMVVCRSKLFAWMYDLVDTHSLDRELVAVAASYMDRYLSKQTSINRGYIYQLVGMTSLYLAIKIYRDQGKCAGAASFAGLSRGLFTDHDIVKMENSMLNTLDWRMFPPTAVTFGTMLLAMIPRGACSPFSRHSMFERIRFLLELSIAVPFFLGKKPSNIAIGAFIEIMESEEQPNVSDKIHQAHFKRRLYILAGIDSDSNEVTICRNAMKKIHQEAKVELKKKDAAIVSPEHCELYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YB29</accession>
    <name>A0AAD8YB29_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein LOW PSII ACCUMULATION 3-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006540</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YB29"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053021">
        <property type="entry name" value="Chloroplast_ADK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018962">
        <property type="entry name" value="DUF1995"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35509">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (DUF1995)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35509:SF1">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (DUF1995)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09353">
        <property type="entry name" value="DUF1995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042212822" evidence="2">
        <location>
            <begin position="21"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1995" evidence="3">
        <location>
            <begin position="57"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="107"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1742943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="366" mass="39780" checksum="8EF3D1BDE38AB2F9" modified="2024-05-29" version="1">MMTRKLLTTTLCIGMAAVSAFQQSSFSSSAAAQSSSSRLSIGKVFGGDNTTKEQQLPKDVKDAISKCRGAVQKALENRLSRMDVEMPVGANFGVEKKKASSSRKRSSLASLTDGGDSSMEGGEEGLTMEKLDTSNRELARLFVEMFQPLGGQHISAVFNDEILADEARKLWSGDLSVECNIVAIDRKGKRSRGGLMGGKKKKKKAKGFASKMAEELEDDGSSGPFNLPKDTEVALFVAPGPKELIAIERICNEVGMGTCVILLNARLSRVEKYASDDARKLFESFEPVWFLGAASQEKSPGCLMHRAYPGKWVLARKPKIGAPKTIAIQDDMFTGDECAEAYATMEVSEIEKTSEKLAMNVAEWFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCK6</accession>
    <name>A0AAD8YCK6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PsbP C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005269</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCK6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019898">
        <property type="term" value="C:extrinsic component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.10">
        <property type="entry name" value="Mog1/PsbP, alpha/beta/alpha sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016123">
        <property type="entry name" value="Mog1/PsbP_a/b/a-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002683">
        <property type="entry name" value="PsbP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31407">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31407:SF16">
        <property type="entry name" value="PSBP DOMAIN-CONTAINING PROTEIN 7, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01789">
        <property type="entry name" value="PsbP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55724">
        <property type="entry name" value="Mog1p/PsbP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PsbP C-terminal" evidence="1">
        <location>
            <begin position="135"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="245" mass="27199" checksum="CC8D43B18AA21B11" modified="2024-05-29" version="1">MMNQTYYSPLRVVLVACSIVVMAMRAEAFHVQPLSLTPSPLRSTEQNLQLPEATESLSRRKIIGQLSSLVMFPILTGATPALAESEEAYVRTPSPNDKFKFSYTITPPPSFAPGNKPLKTHLDEINFSIPDVRGYTLGVTVDPVRIASIKDFGTPEEIAAKVVTAEVNRDGVFQVTLAKDPVEDSAGCYDIEYISDGKRGKKRFGTRIYIQDGFLYVLTVQSKEAEFDEAREKEVQACIKSFRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDJ2</accession>
    <name>A0AAD8YDJ2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">15,16-dihydrobiliverdin:ferredoxin oxidoreductase</fullName>
            <ecNumber evidence="5">1.3.7.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_005211</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HY2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.7.-" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDJ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016636">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010024">
        <property type="term" value="P:phytochromobilin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1500.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009249">
        <property type="entry name" value="Ferredoxin-dep_bilin_Rdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34557">
        <property type="entry name" value="PHYTOCHROMOBILIN:FERREDOXIN OXIDOREDUCTASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34557:SF1">
        <property type="entry name" value="PHYTOCHROMOBILIN:FERREDOXIN OXIDOREDUCTASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05996">
        <property type="entry name" value="Fe_bilin_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041913878" evidence="4">
        <location>
            <begin position="25"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="363"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1743614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="404" mass="45136" checksum="A26639A95DD4E49F" modified="2024-05-29" version="1">MKTQQHFVAAAASAVIASAPLAHAFTSSSNGGCSSCSVTVSRHSPLHMAPSYDSIDAQALLELENRISSVIQADPSSPLALSLGRHAPSPLSMEEAAAQHGMPWDTTIGRTDEENPLLYMPFWEWQLEFMQDSLSNLHPIDCSTLSDTDVTFKENKEKRARIVNQCYASDEYRKIRMTYYDAGDSVQVFNSVWYPDPKYNLPVLGIDILSFNRKKYLAIVDFQPLHEDEDDHATTYEHILQPIKEKYDNLKGRMSSKFYDETQFFSKEMLFARFEDGKIVDNDLLPAFKSYVKTHLNLVQSTPPSTNPQDVQAVFDRQRAYDTYSADRDPAAGLFAAMFGKQWAEDFIYDFLFSLGERSEDGLNLSPPMFGGPPPGAAGKGGPPQKGVNPYAKENKAAQSVPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDY9</accession>
    <name>A0AAD8YDY9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDY9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="110"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="258" mass="29804" checksum="2287DAD763A28BE9" modified="2024-05-29" version="1">MAMNPQLLNQTRLLVEKYDDSLKVNAALNAENRSLRVDIENKEANASTLIEHYQDQICDQTARLEELKEIIRVKDIAEMEEKQRRKVHDDSISIKLHEAGAKEVALLGRIQVLEEEVERMTCAQIQQREESEQKHLSEQVAMKESFENEFESLRQKLVSNMYQEMGDVMAKTMQLNDKLTSQLKTALAEMESMQITLQEKEKEVSFAKREIKLLKYKEKMMAQRIAEKAQARASLVAKTQEEKEKAGGDVVEETQEIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YE79</accession>
    <name>A0AAD8YE79_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005442</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YE79"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1743845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="60" mass="6577" checksum="C54A53829C6BA03A" modified="2024-05-29" version="1">MASKAARIAAVANQIFGTVPNRGVRTGMQYLKKPLTGAMRHDIIWSPLSRLHERCKGSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFA1</accession>
    <name>A0AAD8YFA1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Methylenetetrahydrofolate reductase</fullName>
            <ecNumber evidence="10">1.5.1.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_004433</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the methylenetetrahydrofolate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.20" evidence="10"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFA1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004489">
        <property type="term" value="F:methylenetetrahydrofolate reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00537">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.220:FF:000002">
        <property type="entry name" value="Methylenetetrahydrofolate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004621">
        <property type="entry name" value="Fadh2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003171">
        <property type="entry name" value="Mehydrof_redctse-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053806">
        <property type="entry name" value="MTHFR_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00677">
        <property type="entry name" value="fadh2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45754">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45754:SF3">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02219">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21895">
        <property type="entry name" value="MTHFR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="FAD-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="7 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MTHFR SAM-binding regulatory" evidence="9">
        <location>
            <begin position="402"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="366"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="371"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="385"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF21895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1745142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="697" mass="77559" checksum="17D5A8F080F7B130" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFF3</accession>
    <name>A0AAD8YFF3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_004975</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFF3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006970">
        <property type="entry name" value="PT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04886">
        <property type="entry name" value="PT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="32"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="90"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1744442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="404" mass="44345" checksum="32C2BBFC1F66A68E" modified="2024-05-29" version="1">MMYGESSRPSHTNSLQLGGADVYKRDPDCPSSMPSNVPSEQPSDLPSNVPSDFPSTVPSAVPSTVPSDVPSDLPSDVPSDLPSNVPSDLPSNVPSDVPSTVPSDVPSSLPSQSPSESAQPSDQPSDQPSDQPSDQPSDQSSDEPSSTPSCSPSASPTESPSTEYGVNLFYPDWAAGDSGCRNDGDEPDYMAVNPTQWLSSTMQACCKKYFSGYMYDACMGRYPPDHDDCNVMLYYPDWQGANKACLDDGKEPYYMLSNHQYFLSNSLEECCEKFYDWDFYECSGTTPVLTNGDYYPDWSGGGTSTCLADGKIPDYMIGNQKWYLSTTLKKCCDRHFYWDLNECLGTTAVGTDKWYVDYEDVKCVQDCSGAEPCGGVANFWEELYSTKEQCCKSKLGWVSKCRFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFM4</accession>
    <name>A0AAD8YFM4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Trichome birefringence-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_003985</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PC-esterase family. TBL subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFM4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026057">
        <property type="entry name" value="TBL_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13839">
        <property type="entry name" value="PC-Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trichome birefringence-like C-terminal" evidence="3">
        <location>
            <begin position="860"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="188"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1744694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="944" mass="105423" checksum="D96D16F6E7814952" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YG33</accession>
    <name>A0AAD8YG33_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_003868</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YG33"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1745944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="122" mass="13887" checksum="01A3C7F5F499FD4A" modified="2024-05-29" version="1">MVALIYLATMASEITRNYPRCIATISAGFEKGDFLVREEKGQRVYFDFFEEAFNYIAAKGYSRMSKGEEGEWMELMESIHASVKGGMKYNTGRLLMVLHKPLIPTEYGDEPELESNAMLPMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YH40</accession>
    <name>A0AAD8YH40_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Importin alpha family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_004357</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the importin alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YH40"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061608">
        <property type="term" value="F:nuclear import signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.690">
        <property type="entry name" value="Importin-alpha, importin-beta-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002652">
        <property type="entry name" value="Importin-a_IBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036975">
        <property type="entry name" value="Importin-a_IBB_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23316">
        <property type="entry name" value="IMPORTIN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00514">
        <property type="entry name" value="Arm"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01749">
        <property type="entry name" value="IBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51214">
        <property type="entry name" value="IBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="IBB" evidence="7">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="4">
        <location>
            <begin position="130"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="4">
        <location>
            <begin position="171"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1745066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="419" mass="45903" checksum="F15E7CFD64B71D7E" modified="2024-05-29" version="1">MINNNRDDRRSQFKKGIDADESRRRRTETTISLRKSKKDEGIAKRRARVMAPATMMANDISSSSAPVVYGHSKRDKVFTTQDIPSLMEQLHEIQQSGVMDGDKLKSIAQAFRKIMSVENNPPVHEVLNSGALPYLINMLSLTDKPLVQFEAAWALTNIASTDQTAAIVDAGAIPALVQLLTSASADVREQSAWCLGNIAGDSTALRDVVLAANAMQPLILNIIKPESTSLFSNCVWALSNFCRGKPQPAISQVESAIPAIVDILRGDNEDAKVDALWALSYISDGGEEHIDAVLQCNVAPLLVEILGEESRMLTPALRTVGNIVTGNDKQTQAMLDADLLHKMQFLLNHERRLIKKEACWVLSNVAAGTEKQIGSVLGRYGCMAHVAEMAEHATWEVRKEAIGLSQMLRPVGTSFMFNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YI41</accession>
    <name>A0AAD8YI41_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_002305</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YI41"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042081293" evidence="6">
        <location>
            <begin position="23"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="319"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="7">
        <location>
            <begin position="83"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1746961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="371" mass="40277" checksum="CF05557566447247" modified="2024-05-29" version="1">MGKSNTTALLIIFLLLPWTAVALPCRPNLSNKIMHSRKNHSSPLSSNAKMMTSDESEKLLPLHTEVDKLPAPPTQAKKVGTALFYAVSSLGVIFANKIVLSTYAFPSVQTLAFFQFTSTTVALKIASMLGYVNLLPISWSGIKAILPLSTCYLLNILTGLSATQNLSLPMMVLLRRASILMTMLLEKVMLNSQPSKTVQMSVGLMLAGALVAALGDISFNMMGYIVIFFNDLFTALNGVIMKRTAEEYRKSKMTVLFLNSFLSAIGVAIIIAFVPGEVEKVQNFAEWGNSNFVFYLVFASLLGSVLNLAIFLCTSTNSALTTTVVGCLKNVLTSYLGMFIGGDYIFSWLSFLGINISIAGSLIYAQATFRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YI53</accession>
    <name>A0AAD8YI53_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF2431 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_003560</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YI53"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070042">
        <property type="term" value="F:rRNA (uridine-N3-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019446">
        <property type="entry name" value="BMT5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF26">
        <property type="entry name" value="FERREDOXIN-FOLD ANTICODON-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10354">
        <property type="entry name" value="BMT5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="25S rRNA (uridine-N(3))-methyltransferase BMT5-like" evidence="3">
        <location>
            <begin position="8"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="287"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="305"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1745636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="698" mass="77741" checksum="F628AC92425F7E5C" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIG5</accession>
    <name>A0AAD8YIG5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002687</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIG5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042234539" evidence="2">
        <location>
            <begin position="18"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="592"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="261"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="611" mass="68720" checksum="078323B301958CC7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIM5</accession>
    <name>A0AAD8YIM5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_002777</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIM5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF17">
        <property type="entry name" value="PROTEIN MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1746170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="108" mass="12216" checksum="4EEF407235C14EAE" modified="2024-05-29" version="1">MFKLWPSTAFVPTLIKAFLGQLLFGPAFTTIFFAAGMIQSKSFSFTGWINKIKNDLPKVAASGAGFWMPVSFVSYKFIPQEWIPLFTNLCSFVWTIYLSLVSNRKSTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJ69</accession>
    <name>A0AAD8YJ69_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pentatricopeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002879</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJ69"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140053">
        <property type="term" value="P:mitochondrial gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47938:SF35">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47938">
        <property type="entry name" value="RESPIRATORY COMPLEX I CHAPERONE (CIA84), PUTATIVE (AFU_ORTHOLOGUE AFUA_2G06020)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="PPR" evidence="1">
        <location>
            <begin position="66"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="428" mass="46567" checksum="7985E09B8D21C79A" modified="2024-05-29" version="1" fragment="single">MLTLMRDFYEMNAGKNNRIILSAFEAFLNTLVKNDEVELARDVFDAFFLSIPKDRMQLTGIRPNPTTKHFNIMLGGYSRTGEALKAFELFDTMLDIGVALDGFTVTSLMTHPISPEKITSLLVQVETERAMLNPAAYRSIIGAYGDAGDAASACWMFLEMGRACQKRGRGAESWNVLLGALARGCTGDKVSTALDIYGSFAAKRGNEDLDVEELASDEFISLVDGMTCLDASFTILDMMRSGNQTSLLMQSPKPNSQGYCLLASALSGFGTSASQADRALTLFRDAMKQGGVNPDGRFLNAILRCFGDDIEAALAAWKTDVGPAAASQQGNGNINLQQAYNGLMHVCGRALRPDIATRIAYAMNKAGVEPTEVSLNCYMSGKRVAMEGKTGNSKKGLGLTNQYENLLSVECTKYNTRKWLRANEGQEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJS5</accession>
    <name>A0AAD8YJS5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methionine aminopeptidase</fullName>
            <ecNumber evidence="6">3.4.11.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_003179</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="5">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJS5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004239">
        <property type="term" value="F:initiator methionyl aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01086">
        <property type="entry name" value="MetAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01974">
        <property type="entry name" value="MetAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005069">
        <property type="entry name" value="Nucl-diP-sugar_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002467">
        <property type="entry name" value="Pept_M24A_MAP1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00500">
        <property type="entry name" value="met_pdase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43330">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43330:SF7">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03407">
        <property type="entry name" value="Nucleotid_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00680">
        <property type="entry name" value="MAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5 6" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4 5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042242854" description="Methionine aminopeptidase" evidence="9">
        <location>
            <begin position="22"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="445"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M24" evidence="10">
        <location>
            <begin position="125"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleotide-diphospho-sugar transferase" evidence="11">
        <location>
            <begin position="494"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="349"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="349"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1746572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="761" mass="84824" checksum="879B0D22B02834C6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKE6</accession>
    <name>A0AAD8YKE6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TBC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002309</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKE6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000048">
        <property type="entry name" value="TBC domain containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF27">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="207"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="771"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="776"/>
            <end position="791"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="791" mass="88702" checksum="702533AFEFAF6A5E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YL16</accession>
    <name>A0AAD8YL16_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_002576</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YL16"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF147">
        <property type="entry name" value="SEL1L ADAPTOR SUBUNIT OF ERAD E3 UBIQUITIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="15"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1747232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="263" mass="29250" checksum="3FB323A40C92FB9A" modified="2024-05-29" version="1">MSADTGAGEENTSCCASCGNAEVDDIKLKDCNDCKSVRYCGDKCQREHRTEPSARFNIICNGCDYANLIRELKGSLELKCAFCRHPRISDEELELNLMKRVEANDSAAMCQIGGYRRNEGDYVTAFQHYSKAAELGDAHAHYLLTQMYYNGEGVKKDEKKEVYHLAAIGGNPDARYDLGIAEWHKCRHARAVKHFIIAAKLALKDCYRKGLVSKEDFAAALRGHQAADDATKSPQREEAVLELPKLDAAMDAGICNEECQCCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YL38</accession>
    <name>A0AAD8YL38_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">polynucleotide adenylyltransferase</fullName>
            <ecNumber evidence="5">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">QTG54_000538</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the poly(A) polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YL38"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.590">
        <property type="entry name" value="Poly(A) polymerase predicted RNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011068">
        <property type="entry name" value="NuclTrfase_I-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007012">
        <property type="entry name" value="PolA_pol_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048840">
        <property type="entry name" value="PolA_pol_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10682">
        <property type="entry name" value="POLY A POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10682:SF10">
        <property type="entry name" value="POLYNUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04928">
        <property type="entry name" value="PAP_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20750">
        <property type="entry name" value="PAP_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55003">
        <property type="entry name" value="PAP/Archaeal CCA-adding enzyme, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly(A) polymerase nucleotidyltransferase" evidence="16">
        <location>
            <begin position="590"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase central" evidence="15">
        <location>
            <begin position="783"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="209"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1011"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1178"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="36"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="210"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="1011"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="1021"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="1063"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="1179"/>
            <end position="1197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF20750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1748599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1273" mass="142927" checksum="700305F186EC5769" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YL50</accession>
    <name>A0AAD8YL50_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001318</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YL50"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041949667" evidence="2">
        <location>
            <begin position="18"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="230" mass="24796" checksum="B215D3ADB60ED7B1" modified="2024-05-29" version="1">MMRSGLLTGLLATSASAFVSPRLPVAQQVRPSHSAIALSNHDDTDHKAAAPADVLRNAAAIFAVTCGLLYPSDSFAMNESAFQSSTMTVAEVIRTMDFSLPSSYDTIVDVQADTKEELTEETITSAAGTAKKASPKKEAAQKKEKKEAAPKKVAMTKAEREEAQARAKEEKAKEDAEKQLEIEAKIKADREKKIAARKAAQEEKEAAAAEKAEAAYVKDVKFVDTSMPTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLQ0</accession>
    <name>A0AAD8YLQ0_9STRA</name>
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        <submittedName>
            <fullName evidence="8">AP2/ERF family transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_000835</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLQ0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00380">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51032">
        <property type="entry name" value="AP2_ERF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="291"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="109"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="256"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="393"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="19"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="126"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="414"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="548"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1748896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="610" mass="66972" checksum="D8EE3D865F01DFFF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPF0</accession>
    <name>A0AAD8YPF0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cleavage and polyadenylation specificity factor subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000804</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="2">
        <location>
            <begin position="1455"/>
            <end position="1822"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="623"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="623"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="641"/>
            <end position="653"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1857" mass="199866" checksum="53E50D48C96BE8BF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPT2</accession>
    <name>A0AAD8YPT2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cysteine desulfurase</fullName>
            <ecNumber evidence="4">2.8.1.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_001223</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPT2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601:SF34">
        <property type="entry name" value="CYSTEINE DESULFURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601">
        <property type="entry name" value="CYSTEINE DESULFURYLASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="3">
        <location>
            <begin position="62"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1749284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="482" mass="51192" checksum="F840A32F67955838" modified="2024-05-29" version="1">MKALLAGCRSLITTNCKPKSISESCISSSSFVHHFITTSTSGGSERTYNNIIMEATKQKTCVYLDYNGTTPVYPPVLEAMLPYLTDHFGNPSSSHHFGSEPKAAVNKARRSLLSLIQSVPIADLSSIMFTGCGTESNNVAIRLALLSSTHKVDKDGLLQVVTTNIEHPAITQCLNSYIRGGLTPKITVTEVPVDEFGRVSSPDVIDAIQENTALVTIMTANNEVGSLQPVFEIAKICRQKHVLFHTDAAQAVGKVDLRGLADETTGADMVTIVGHKFGAPKGIAALYIRPNCLDENGRVNPEHGGSVLLMGGGQEGGRRGGTENVPYIAGMGKAADMLFEQRGDRSGLEANAMHMQKMRSRLLEQIATGLEESTGKTDISRVNGPLNADQRLPNTLSIGLKGVQSGRLLADIGEVVACSAGSACHSSSGPTMSYSAILKAMNVPPDVAVGTLRLSVGPNTSLEDVDFAADVIVKEATRQLNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YQ78</accession>
    <name>A0AAD8YQ78_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001224</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YQ78"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042157740" evidence="1">
        <location>
            <begin position="16"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1749285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="356" mass="37758" checksum="B4B74574538BF25B" modified="2024-05-29" version="1">MRSFLLLHCCTLVAAASSPSELWKAAKAAVTSADESDEGADWTSVILDRSSKNQDAYVSASPLSVAAVCSDGIALVSLHFGLELNDDNDDAQSSSQTEGNELLEVFNDLPLSSRGPLRIEPIYDNGAAKNSMTSTCSLRSPPSLALLTAGWRTDGMALSDAARELMMEETSLYCLPLSVTMGANDNNGGATMNNGQISHYGRRIADGLSYYMAKCAFSEGVRSLSTIGLLACNNSAGGCLYLVDATGSYSVRAHAIGNGASTIHKRLVFVNFEDMTTLEGLRMLLRIIAEEGGVLSTESASSNAGKQNKPAGAAWTIPRNPGVELAILRIGEQRMRRIRLSSLFTAAGTEEQGKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3S9</accession>
    <name>A0AAD9D3S9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016688</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000062">
        <property type="protein sequence ID" value="KAK1732627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3S9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="342" mass="38514" checksum="7AD39ABB1C7E8249" modified="2024-05-29" version="1">MANYRIGLNLLQANVINVRASSHSPPVIYLYKGGPVPRHVTHIRIDKSIKVIPDELFSGSNVQVVEMHDGVYKIGKLAFYNCRCLERISGATGVRLIDEGAFYRCRRLKDVEFGSEKLERIGVGAFTRCGSLRGLKLPSVKIVESHAFQFCINMTDVEFGERLERMGESALLNCYSLRRVAMPLREDLISDNIFKGCTNMASLELVGEVHNTISHFSLQVWKDVMKYEIDAINQVLPAVPADGNKTLAVRQWIRRVRTRVEHFTTEHNSSLEESATILELSLWRDNLIGETSHGNGSDSSLEAKPNKRARIDVDSDSARQERRMTCGANIVVKNVLPFLQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D410</accession>
    <name>A0AAD9D410_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_016259</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000054">
        <property type="protein sequence ID" value="KAK1733121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Tiny_macrocysts_regulators"/>
    </dbReference>
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        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GAMETE ENRICHED GENE 10 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31600">
        <property type="entry name" value="TINY MACROCYSTS PROTEIN B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="3">
        <location>
            <begin position="808"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="1067"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="370"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="486"/>
            <end position="510"/>
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            <end position="1290"/>
        </location>
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        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="156"/>
            <end position="172"/>
        </location>
    </feature>
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        <location>
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        <location>
            <begin position="242"/>
            <end position="257"/>
        </location>
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        <location>
            <begin position="265"/>
            <end position="275"/>
        </location>
    </feature>
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        <location>
            <begin position="299"/>
            <end position="315"/>
        </location>
    </feature>
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        <location>
            <begin position="322"/>
            <end position="336"/>
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        <location>
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            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="347"/>
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            <begin position="563"/>
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        <location>
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            <end position="621"/>
        </location>
    </feature>
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        <location>
            <begin position="626"/>
            <end position="635"/>
        </location>
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    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="636"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1165"/>
            <end position="1175"/>
        </location>
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        <location>
            <begin position="1179"/>
            <end position="1215"/>
        </location>
    </feature>
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        <location>
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            <end position="1236"/>
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        <location>
            <begin position="1237"/>
            <end position="1272"/>
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    </feature>
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        <location>
            <begin position="1280"/>
            <end position="1290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1733121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1290" mass="138235" checksum="85DA728CD99A8B81" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D441</accession>
    <name>A0AAD9D441_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">WLM domain-containing metallopeptidase</fullName>
            <ecNumber evidence="3">3.4.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016908</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <location>
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            <end position="398"/>
        </location>
    </feature>
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            <end position="404"/>
        </location>
    </feature>
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            <end position="383"/>
        </location>
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            <end position="404"/>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="404" mass="44501" checksum="A8B9A16402527949" modified="2024-05-29" version="1">MNAVKFSFKGRSETVTAPESISSSALLALARKSLQIDDDIVLKLIFKGKTIAQQNVPTNGSSTADEDSKRAFPEGVKIPKSGAKVIVMGTMTSGIATLNSMRSDPLMRGFDEEKLVSKAKNGTMSTFWGPKLGSQHPKYKFCRLEECKDASFGTRPTSSTPHAFEARRLLEQLATDPGVVQVLTSRELVVGCLGEMDPIDDRLMQKKKEEGACLLGYNTNHGLRIDIKLRTDDLNGFRPYNELASTLIHEVSHNWVSEHDVLFWTNYGQMRVEYLWKHACYILGGLFVNGKRTASLAGIMDMIVFPSDGKDTPTKPKLMDNICQSVVKELAGEMMQHRLPVQLVAPAVIGFGKDLMMETKDDSIGIGKGQRLGTVSNDENSGLSARERALAAAEKRAREAKEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D481</accession>
    <name>A0AAD9D481_9STRA</name>
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        <recommendedName>
            <fullName evidence="5">Lon N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016872</name>
    </gene>
    <organism evidence="3 4">
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        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
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            <taxon>Ochrophyta</taxon>
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            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
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            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000066">
        <property type="protein sequence ID" value="KAK1732478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041956395" description="Lon N-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="26"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="485" mass="53637" checksum="95A6A584A8C1EDDD" modified="2024-05-29" version="1">MMLSLSMPSFTFLVSMMWTLQAVQCLTTFRPISRTTISTSSSRLNMNYGRNIAKKNVKLPLLVDINNESGYSVPLPNHHLPPELTTASLYQLDLAIPIHKSVIQDAVQKKGGSIDELCYYGHVVSNPADQDGLIGAIGCASEILIATPASITSEEVLEERGDTEQTSDKFDADDSGVLHVLSRGAFRFRVKEVVNSIPYPVAIVDELMDEDEDDVNDQDEEEEKGDDDDDDDDDIYATLPAKSLIQQILQSLDTILQKEIEATAAPLSPLEQSILETADTASPMMQAIQRQFDAEERLANFQVFRNSLLDIASDARDRAFCVGMMAAELANLPSSTRVKMLETVNGTHRLRIVMRKLSSILAMDSARRVAKSLSLQGGGDGDVKDIKTDLKSLKEAEESKKDLKVGKPSLPQWAGQIQRGVRVEYFWNEVEGWCLGTVCEDPVKVLDEVIISVKFDDDGSIHKLPLRGEDKARWRPPMGDTGAFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4R2</accession>
    <name>A0AAD9D4R2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome b561 and DOMON domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_015562</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000045">
        <property type="protein sequence ID" value="KAK1733707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4R2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09631">
        <property type="entry name" value="DOMON_DOH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045266">
        <property type="entry name" value="DOH_DOMON"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23130">
        <property type="entry name" value="CYTOCHROME B561 AND DOMON DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23130:SF171">
        <property type="entry name" value="OS01G0895300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03188">
        <property type="entry name" value="Cytochrom_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03351">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00665">
        <property type="entry name" value="B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00664">
        <property type="entry name" value="DoH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50939">
        <property type="entry name" value="CYTOCHROME_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50836">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041969207" evidence="10">
        <location>
            <begin position="23"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="929"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="968"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1001"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1046"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1083"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="domain" description="DOMON" evidence="11">
        <location>
            <begin position="433"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="domain" description="DOMON" evidence="11">
        <location>
            <begin position="775"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="12">
        <location>
            <begin position="895"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="739"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1111"/>
            <end position="1130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1733707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1130" mass="119227" checksum="A30D7830884774B4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5A0</accession>
    <name>A0AAD9D5A0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Trypsin-like serine protease</fullName>
            <ecNumber evidence="8">3.4.21.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_015853</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000049">
        <property type="protein sequence ID" value="KAK1733438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5A0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000002">
        <property type="entry name" value="Transmembrane protease serine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF91">
        <property type="entry name" value="AT26814P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042234211" evidence="6">
        <location>
            <begin position="25"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="7">
        <location>
            <begin position="90"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="403"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="414"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="424"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="455"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1733438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="627" mass="67460" checksum="29AB4E995A4A9950" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5S8</accession>
    <name>A0AAD9D5S8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA ligase (NAD(+))</fullName>
            <ecNumber evidence="1">6.5.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_014212</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>NAD(+) + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide.</text>
            <dbReference type="EC" id="6.5.1.2"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.2" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5S8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003911">
        <property type="term" value="F:DNA ligase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17748">
        <property type="entry name" value="BRCT_DNA_ligase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.610">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01588">
        <property type="entry name" value="DNA_ligase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001679">
        <property type="entry name" value="DNA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033136">
        <property type="entry name" value="DNA_ligase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013839">
        <property type="entry name" value="DNAligase_adenylation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013840">
        <property type="entry name" value="DNAligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004150">
        <property type="entry name" value="NAD_DNA_ligase_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005932">
        <property type="entry name" value="PRK07956.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01653">
        <property type="entry name" value="DNA_ligase_aden"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03120">
        <property type="entry name" value="OB_DNA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00532">
        <property type="entry name" value="LIGANc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01056">
        <property type="entry name" value="DNA_LIGASE_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="BRCT" evidence="12">
        <location>
            <begin position="960"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="216"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="232"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00034005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1735146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1039" mass="112399" checksum="0B2C567241CCA619" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5T1</accession>
    <name>A0AAD9D5T1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1733963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5T1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="416" mass="47818" checksum="21691CE7BEA66C96" modified="2024-05-29" version="1">MRRITRSSRRPIGRSSSIRTTFFILSFVATCRLLQPTPTWMTYPSSLRASPTSGGFQHYLDIALDLASLEPSEVLATMEQIDPFQTKAFDILLSQKETALKRTLTIDEIKDIFPCPRLDERITLPDARVDQKAKDFRNGKHGTFLFFQHLRKAGGTNFCSLAENNLPEKAQPAYYCMPDREWKEKKGAGRLHSWSNEEITTRMSKQGFRIAGNEWEYFDPSRHFDLPAVFATSFRKPIDRALSQFRFECIEDRGCIIKDVHKWWEKRVDLWNVYTKTFADPPGGARNQFNGTEQRREMMATAIDTLSKFHIVLSMEWLAYAAPQVRSILGFNDVSALTTRVRPHINQAKRDDRQEHNSLGSASIKKASWDPKEYLDAAQYKKMSEDLALDEILTEVARRMFLERLVCNDLGGGVAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D640</accession>
    <name>A0AAD9D640_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">VWA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_014288</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00198">
        <property type="entry name" value="vWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF3">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1124"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="3">
        <location>
            <begin position="1379"/>
            <end position="1586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="852"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="976"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1082"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1330"/>
            <end position="1371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1000"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1330"/>
            <end position="1348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1349"/>
            <end position="1359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1360"/>
            <end position="1371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1735222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1589" mass="172093" checksum="7ADB4B13F102CBC8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D678</accession>
    <name>A0AAD9D678_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH OST-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014875</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D678"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025605">
        <property type="entry name" value="OST-HTH/LOTUS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12872">
        <property type="entry name" value="OST-HTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH OST-type" evidence="2">
        <location>
            <begin position="7"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="468"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="480"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="605" mass="68369" checksum="84F6A114202E1BB2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7S0</accession>
    <name>A0AAD9D7S0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">60S ribosomal protein L3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_012009</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7S0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1430.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.960.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000351">
        <property type="entry name" value="Ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.960.10">
        <property type="entry name" value="Ribosomal protein L3, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045077">
        <property type="entry name" value="L3_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044892">
        <property type="entry name" value="Ribosomal_L3_dom_3_arc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_uL3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_uL3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11363">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11363:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="13"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1737142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="391" mass="44239" checksum="D23E343244F222FF" modified="2024-05-29" version="1">MSHRKFEAPRCGNLGFLPKKRTKHHTGRIRSFPKDTDASAPCHLTAFRAYKAGMTHVVRGVDRPGAIMHKREVVDAVSILETPPMVIVGVVGYLETPRGLRTLTTVFAEHLSEEFKRRCYKNWYKSKRKAYSKYAKKYTENDGKDIEKELERITKFCKVVRVITHSQPKKLHLRLKKAHIMEIQINGGADSKAKVDFAKSLFEKEVTVDSVFAKDELVDVMGVTKGHGFEGVTTRWGVSRLPRKTHRGLRKVACIGSWHPARVSSTVPRAGQNGYFHRTEMNKKIYRVGKKGDNASCQTEADLTEKGVNPMGGFVHYGTVREDWVMIKGACVGVKKRPLILRKALMKHSSRKHLEAIDLRFIDTSSKLGHGRFQTAEEKAKFLGPMASKQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7V2</accession>
    <name>A0AAD9D7V2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_011742</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7V2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045877">
        <property type="entry name" value="ZFP36-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547">
        <property type="entry name" value="CCCH ZINC FINGER/TIS11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547:SF18">
        <property type="entry name" value="PROTEIN TIS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="22"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="75"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="22"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="75"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1737456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="262" mass="28574" checksum="A59671B1120AD120" modified="2024-05-29" version="1">MSPASASPTPQNLKDNPERLAKVKTEMCRYYELGGLKNCPWGDKCNYAHGKHELKFNHTTLTLMERSGQIANAKTYLSRPCMTWISTGACPYGRRCPAIHDPSITGPLENPSWLPAASAKTNAQIIVDRFAAHRDSAVHQENPLIAQGIWENCRPSATSQCDGGDESEVSWLDTYALVCNMGVPTFGRGHLPILTAMRCHPSTSSSNKLSDLRSCASSAKCEDRTAPSVVAVVADVKGRSSFIYCTVTTSMHPPTRLTLSFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7V7</accession>
    <name>A0AAD9D7V7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_011757</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="3">
        <location>
            <begin position="423"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="48"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="294"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="845"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="318"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1737471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1419" mass="158798" checksum="40CB4DB5E25824E3" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8B7</accession>
    <name>A0AAD9D8B7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cGMP-dependent protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">QTG54_011544</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.12"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.12" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8B7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030553">
        <property type="term" value="F:cGMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004692">
        <property type="term" value="F:cGMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF143">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0140">cGMP</keyword>
    <keyword evidence="9" id="KW-0142">cGMP-binding</keyword>
    <keyword evidence="7 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="14">
        <location>
            <begin position="141"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="14">
        <location>
            <begin position="260"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="543"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="15">
        <location>
            <begin position="806"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="15"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="60"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1737772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="867" mass="97299" checksum="E9AE248841C3ED4C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DB27</accession>
    <name>A0AAD9DB27_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Adenosylcobinamide kinase</fullName>
            <ecNumber evidence="8">2.7.1.156</ecNumber>
            <ecNumber evidence="9">2.7.7.62</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Adenosylcobinamide-phosphate guanylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">QTG54_009848</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosylcob(III)inamide + ATP = adenosylcob(III)inamide phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15769"/>
            <dbReference type="ChEBI" id="CHEBI:2480"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58502"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.156"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>adenosylcob(III)inamide + GTP = adenosylcob(III)inamide phosphate + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15765"/>
            <dbReference type="ChEBI" id="CHEBI:2480"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58502"/>
            <dbReference type="EC" id="2.7.1.156"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>adenosylcob(III)inamide phosphate + GTP + H(+) = adenosylcob(III)inamide-GDP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22712"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58502"/>
            <dbReference type="ChEBI" id="CHEBI:60487"/>
            <dbReference type="EC" id="2.7.7.62"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 5/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 6/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the CobU/CobP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.156" evidence="8"/>
    <dbReference type="EC" id="2.7.7.62" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DB27"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043752">
        <property type="term" value="F:adenosylcobinamide kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008820">
        <property type="term" value="F:cobinamide phosphate guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00544">
        <property type="entry name" value="CobU"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003203">
        <property type="entry name" value="CobU/CobP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025595">
        <property type="entry name" value="PterinBD-DUF4346"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34848">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34848:SF1">
        <property type="entry name" value="BIFUNCTIONAL ADENOSYLCOBALAMIN BIOSYNTHESIS PROTEIN COBU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02283">
        <property type="entry name" value="CobU"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14251">
        <property type="entry name" value="PterinBD-DUF4346"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="15" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="13 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 19" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DUF4346" evidence="18">
        <location>
            <begin position="290"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4346" evidence="18">
        <location>
            <begin position="614"/>
            <end position="718"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00003889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00007490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00012016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00012523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00029570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00030571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF14251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK1739305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="718" mass="80373" checksum="B8529E938CE570F1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBS2</accession>
    <name>A0AAD9DBS2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBS2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="1">
        <location>
            <begin position="62"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="885"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="885" mass="100158" checksum="D3FAECF209EB4101" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DC08</accession>
    <name>A0AAD9DC08_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mutator-like transposase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008539</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DC08"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049012">
        <property type="entry name" value="Mutator_transp_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20700">
        <property type="entry name" value="Mutator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mutator-like transposase" evidence="2">
        <location>
            <begin position="211"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="494" mass="55251" checksum="D76A8536958D8A30" modified="2024-05-29" version="1">MTSILQTSNCEGDELVLLLIHCLPPDIAKLWHTTEDMLVMLKAGGITSYTTSKRIGNLLRTQKRICLEPNRTNHKNHYCFNEKGKEYDDPVQQRNAFREKGRPQIETNYFTKLGITFKFMKTSTTQTTANATTSNNATAATSAAAKNNNNIYNNVKKSNIMSGATTTNNNKNNNSTPKKRSTSSTPSIATETGYMIAHLGIVEEVLAANAEHRKTCRSMLLVHDKRRFGFEVFTDLGCKFCKKTYTIRSGPKPTEAPKVNTPQQQQQQKKKRGRKASPLNMTNGMHASAITIAQMQGLCGEVGIVSPSETGQHNMMRMRKDAIKVVAEEVLKENRKEHVRMCKEMNPDNTIKHKDKDGKEHNICYGPVSADGAGEKRAYNHIITGSQHCTVVFSLVTSKVIAVKHDQISCAKCAQRLTHLVAVDKKRAEDIKEEDLKHDGQCYINSKHGPAVAEEYALETASKWESSTMKSRPWLTSPQLSQCLLNRRFSVRAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DC23</accession>
    <name>A0AAD9DC23_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009258</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DC23"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="159" mass="18073" checksum="7EE8D5BEFFA7ABF9" modified="2024-05-29" version="1">MFKLRYSRKACIIEWDSASFTDCRPCEANAIEEEIIELVQALEFGPEWCEGVDSLTLEKANEEARLVCEREVLEALDGFDNLPHASTMWDEYKESNTVDLKLRDWGDERVTDANRKKNKDGTVSYEAHTIHFADPYGGLCNVVQLDIKVEVVPADKAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCM6</accession>
    <name>A0AAD9DCM6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FAD-binding domain-containing protein</fullName>
            <ecNumber evidence="4">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006273</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCM6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050432">
        <property type="entry name" value="FAD-linked_Oxidoreductases_BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878:SF91">
        <property type="entry name" value="FAD BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G12070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878">
        <property type="entry name" value="GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="3">
        <location>
            <begin position="50"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1742676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="199" mass="21343" checksum="C562B7FCB2FE8F25" modified="2024-05-29" version="1">MCLPHSYLGWEKSWSRPSENGHLNQTFDQAFTDLFVNPWTDLVLDPTNPSLNLPSKVLFPTVASDVVAAVNFAKDNGLEISVKNSGHSYQGASSKKNTLLLNMNRYTHYAPTGIMDCDASNLGSTVAEDLSNQPCLLSLAKNKSSLIRVGGGENFDKVFRAVIAANEEEGYKYHLGGAAGTVSPMGWSWQGGLGGTTGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DD05</accession>
    <name>A0AAD9DD05_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NAD(P)-dependent epimerase/dehydratase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_007703</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008446">
        <property type="term" value="F:GDP-mannose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042351">
        <property type="term" value="P:'de novo' GDP-L-fucose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006368">
        <property type="entry name" value="GDP_Man_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43715:SF1">
        <property type="entry name" value="GDP-MANNOSE 4,6 DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43715">
        <property type="entry name" value="GDP-MANNOSE 4,6-DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="4">
        <location>
            <begin position="740"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="191"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="427"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="508"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="619"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="89"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="196"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="209"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="234"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="265"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="313"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="332"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="432"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1741225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1468" mass="165328" checksum="F7A98B60CF974C88" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDS6</accession>
    <name>A0AAD9DDS6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Polysaccharide pyruvyl transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007561</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDS6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="470" mass="53089" checksum="E1F8EEDCF217E5F3" modified="2024-05-29" version="1">MVLRGADTEKGHQRRGSPNNSNHAAAMCRRLLFSRQWYRTLIVVIPVFSCMQYFIFYPTATRGVAQEQDVRSSVISRTMTDPKAKRKIVLLGPHDRYNFGDLIFTSVVAKLLVSRAGFSPDDLLFGGIVTVDMTKYGGYKILSMKQIQSLSQEDTEQGPYDIIYLGGEALGCDFNCAVGMLPDERMKTEARREKINDCPYLVPKHLLLPPSMPKNDTFQMKNYAVINSMGGTPCNGCKKAIETADYIAFRDKNPLFPDSAVMMKELYPIKSVKQLKRCCRISSPAEQKIIAVQHRDIPTEEARLELALALDKVSKEGHATIVFFAAGTVPGHDSISCYKKVAQLMTEPSIVYEVENMWKIVGLISQAEAVLSTSLHVRIISFLYLRPRLTWCGHEPKHPQFIALWDTDESPRCLESKNETWSVLQRHYGPNPNVTQAATDIAYEKMVKKYLKSFDSWSSLVGWRRYSTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DE13</accession>
    <name>A0AAD9DE13_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutathionyl-hydroquinone reductase</fullName>
            <ecNumber evidence="5">1.8.5.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_006870</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.5.7" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DE13"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03190">
        <property type="entry name" value="GST_C_Omega_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047047">
        <property type="entry name" value="GST_Omega-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016639">
        <property type="entry name" value="GST_Omega/GSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32419:SF6">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE OMEGA-LIKE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32419">
        <property type="entry name" value="GLUTATHIONYL-HYDROQUINONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13410">
        <property type="entry name" value="GST_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015753">
        <property type="entry name" value="GST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01206">
        <property type="entry name" value="Xi.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01148">
        <property type="entry name" value="Xi_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="4">
        <location>
            <begin position="27"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="28"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="1">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>glutathione</name>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="122"/>
            <end position="125"/>
        </location>
        <ligand>
            <name>glutathione</name>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="140"/>
            <end position="141"/>
        </location>
        <ligand>
            <name>glutathione</name>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Cys" evidence="3">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <feature type="site" description="Lowers pKa of active site Cys" evidence="3">
        <location>
            <position position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR015753-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR015753-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR015753-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1742305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="355" mass="40222" checksum="00866429259CF9E6" modified="2024-05-29" version="1">MAQHHKQGARLHVSPEKDRYHLYVAHACPWAHRTLIARALKGLEDVISITVVMPIWQRTNPKDEHVGWMFADHSSSGNNVVTNSAGLGGPFPASYPSNEADPIFNARSVREIYEKVNDKDGKYTVPILFDKKLKTIVSNESSEIIQMLNSEFDEYASCAEVDLEPEDMKEAMAAVDSWIYPSLNNGVYKCGFAHTQEAYNAAIDELTAAFDRAEDILSTQRFIAGKRFTLSDIRLFVTLLRFDEVYVVYFKTNTRSVANSSVLLNYCRDIYQMDGVAETVDMHQIKEHYFCSHPDLNKFSIVPRGPDFERLLQAPHGRESFDVKRRRISKGQVSISDEDKSTLKSDVSVDSLEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DE39</accession>
    <name>A0AAD9DE39_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Mechanosensitive ion channel family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_005519</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DE39"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_beta-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30566:SF5">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30566">
        <property type="entry name" value="YNAI-RELATED MECHANOSENSITIVE ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Mechanosensitive ion channel MscS" evidence="5">
        <location>
            <begin position="271"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1743922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="445" mass="48868" checksum="D9CE84F8DD7079D3" modified="2024-05-29" version="1">MTLTSMLIDLRMRGGTSVYEGISTQKTRVTHLCNDPKDHDDRIFLNHLPGVGYATMQVIPLLLIAIVQAVSAFQYPCSNYVGHHHHHDVGRRHTTLQSIEDPTLIEELSISGTIGLLANSIVERTGMANDLVKDEPTMNDSSESTSSLLLYGIADSIDDTAWVYFFLTLVAAIDTQFDIHYVDSDILKAAIPTIANIIKYQAYTALATNFRKKLGRTRIYDQFIDFILTFCTCGVILSELQLDDNIGMGFQSLFAISGASAVFFSLVSKDLAEHIVGGLAVQVWDAFSVGETITLGNGLSGKVVSIGLVETEIESSNDVITKIPNSKIVNERVSNISRATKSQVVQTLRFSYGDIKLVPKVLADIQEEIEASCPKLDHGTAMLKSYEADHIQTEVNYHFDIPPANVVEYGSNREQVLLAIGRAIDKNNVTFAIPAINYVNTESAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEE7</accession>
    <name>A0AAD9DEE7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEE7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="480"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="324"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="483"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="807" mass="85841" checksum="C52F7D8D63FBB19B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEY1</accession>
    <name>A0AAD9DEY1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_004427</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 5"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEY1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43811">
        <property type="entry name" value="FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43811:SF26">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP16-1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042041019" description="peptidylprolyl isomerase" evidence="6">
        <location>
            <begin position="20"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="7">
        <location>
            <begin position="90"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1745136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="217" mass="23208" checksum="D89BFD59BA2A8186" modified="2024-05-29" version="1">MMLSAKALLATLLLSATSAWQAPQPVNHQVSDNARRSLLVNAPIFALSSFATVSNASTDTSNLKFTTSPTGLQYADVKEGPSSTPSPSDGQTVSIDYVMSTTGARYGSKIYSTVDAGAPYRWKLGDGSTIPGLEEAVKGMNPGGIRRVIIPSKLAYQSASTPISIIQECESGKGLGPIPPVETAVGEFQRFKNIYCNPDRQYQPDLVMDVKLYGKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFA0</accession>
    <name>A0AAD9DFA0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_005252</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFA0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042090708" description="Fe2OG dioxygenase domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="542"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1743655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="707" mass="76454" checksum="2274712ABE6DAAAC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFH3</accession>
    <name>A0AAD9DFH3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004787</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFH3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="257" mass="29363" checksum="DB4123A4A87414EA" modified="2024-05-29" version="1">MDLNARPTRNFWDIFHCCRNIGEGENDENPTKFSATNNYAFMKFLDTKGTDMMNTSAADSVNTPTTVATADSKLETITEDDNIFDDDLSEVAMEETEQQNSESEKEADFNEQDASFIYDKMTNLAEQQDDDMPDMDSYLNDDGNTKTTKDDTATQRCNQTAAGEVTFYHFFIFMILRHIFGPLLVGMSVKKKKNVSYWEKFLSFTNCSSIDKHDDEKPSKESVRTMKLRQLKLDEGKCEVYPSLSDVPPILEDEILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHP5</accession>
    <name>A0AAD9DHP5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pyridoxamine 5'-phosphate oxidase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_000135</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHP5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024624">
        <property type="entry name" value="Pyridox_Oxase_Alr4036_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28243">
        <property type="entry name" value="AGL049CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28243:SF1">
        <property type="entry name" value="PYRIDOXAMINE 5'-PHOSPHATE OXIDASE ALR4036 FAMILY FMN-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12766">
        <property type="entry name" value="Pyridox_oxase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042120804" evidence="2">
        <location>
            <begin position="19"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridoxamine 5'-phosphate oxidase Alr4036 family FMN-binding" evidence="3">
        <location>
            <begin position="76"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1748196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="324" mass="36767" checksum="C169E46908CE996B" modified="2024-05-29" version="1">MPLLLLSLRQLLPVSSFAAHQQAAAFSHLPRITNRQTSSTNFCASRKMTSNNNEQQQGLADIGDNNNSSSSNPDMKTWKERIDISIAKSRKVRGSNYVQISTIDYETMEPRCRTVVFRGFMKDLPFGAVEEVLLGDSAQEEDDSSLSSSGKYTDCVMKMITDLRSNKVSEVESFQTTGKKNGNTVEMVWWFPKSSEQYRIRGNLQFIGNGGPLTNTNDATSNHNDYFVGERKQQWGNLSDMAREQFYWDNPGIPYCSVKGHEQGVPPGGRDDEGKVLPVPDSFLLMLLYPTKIDYLKLGENYRQIDEWKWEGGESQWEQLRMNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJJ2</accession>
    <name>A0AAD9DJJ2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002013</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1748050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJJ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="196"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="229"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="283" mass="31833" checksum="26266EF262D21255" modified="2024-05-29" version="1">MSSHHHRSRLHFLLCLYYHSRDAITLATISAIVVRFTDLSGSLDTESVPWKFVLWLTGINPSTILRVWQVMIGMLPFPSSPRTRKGTGTGGELSSSSKKVDKQEEEGDMSRNQKRFICHELIHTITGFYHIIPLQGLVWMAMINFPLWFAHLDLCMSEKELLVGSLSSSTSPRKNMAKRSHQVVQNDHDPLVVFSIVIYVVGVFFRGQSFLLSGAGVVIMSLPFTRRKAAFSVAATVPPLVVLFALEHFTIMSEMETWHNAVHSLSHMALHVAVNSLFKHHVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJR7</accession>
    <name>A0AAD9DJR7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001981</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1748018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJR7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050656">
        <property type="entry name" value="PINX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23149">
        <property type="entry name" value="G PATCH DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23149:SF9">
        <property type="entry name" value="G PATCH DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="2">
        <location>
            <begin position="16"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="242" mass="26662" checksum="3FBAFF1ACD941CFE" modified="2024-05-29" version="1">MTIVATQDTRNSDWATSSFGRKMLEKMGWKGDGVGLGKNQQGTSTHLRAVKRAESLGIGAETDAFGDSGWQQTNAAFHGVLANLKKEHGNNSGSDDDDNKEARKKRKKEEKKRKKKEEKRRAKAAADGGGASSTDGGVSGIRLAQNKVQAGHARKMRDAKDIKNKSAADMAAIFGVKADFYKQPKEWVITTTTPAEVTDSSTEVKEAEKERKKAKKSSKEKKKRKHSPDDEDTKEKRKKSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DKA7</accession>
    <name>A0AAD9DKA7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_000844</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DKA7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1748905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="222" mass="25443" checksum="9AB21D0AAC669D99" modified="2024-05-29" version="1">MCIDLERDECCATDYDRHAMVLLLYRECLVKLGACMKKSDARRRAHIEEMGRIERRQDALVILSSIFDNYSSSERPVTTKCSSHSPKIHHYYHTVIHIELGLLIFLCVLCCNSQRLYTFAIIDPRLNKLISIGEITSIRGCCSSVAKKLASADDKADLAWWCSQQYSMGSSDQLKCLDLATQMLRSLLMKLNQWVTDLTRNALHWIEYNESILQEPACLTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DKH3</accession>
    <name>A0AAD9DKH3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Delta-4 fatty acid desaturase</fullName>
            <ecNumber evidence="3">1.14.19.31</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000647</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.31" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DKH3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016717">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042759">
        <property type="term" value="P:long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006636">
        <property type="term" value="P:unsaturated fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03506">
        <property type="entry name" value="Delta6-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353:SF19">
        <property type="entry name" value="DELTA(5) FATTY ACID DESATURASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353">
        <property type="entry name" value="FATTY ACID DESATURASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015921">
        <property type="entry name" value="FA_sphinglp_des"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="339"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="363"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="2">
        <location>
            <begin position="23"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="529" mass="59437" checksum="135C76EE201EC99A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2P4I1</accession>
    <name>A0A7S2P4I1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">poly(A)-specific ribonuclease</fullName>
            <ecNumber evidence="5">3.1.13.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">QTG54_004515</name>
        <name evidence="16" type="ORF">SMAR0320_LOCUS2795</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Exonucleolytic cleavage of poly(A) to 5'-AMP.</text>
            <dbReference type="EC" id="3.1.13.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CAF1 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.4" evidence="5"/>
    <dbReference type="EMBL" id="HBGZ01004101">
        <property type="protein sequence ID" value="CAD9578359.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S2P4I1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030014">
        <property type="term" value="C:CCR4-NOT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004535">
        <property type="term" value="F:poly(A)-specific ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000048">
        <property type="entry name" value="CCR4-associated factor 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039637">
        <property type="entry name" value="CNOT7/CNOT8/Pop2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006941">
        <property type="entry name" value="RNase_CAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10797">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04857">
        <property type="entry name" value="CAF1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="9 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="13" id="KW-0804">Transcription</keyword>
    <keyword evidence="12" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CAD9578359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1745224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="349" mass="38901" checksum="9D6D997396A58658" modified="2021-06-02" version="1">MASVLTMESPPFQPRSSGGSSAASSFASPHHHRIRSGASSPLSHGSSGGEAHSNAVRSYTFQTPSGEALEIRNVWEENVEEEMAIIRELIDTHPYVAMDTEFPGVVARPVSETYSPDFHYKSLKCNVDLLKIIQLGLTFADEDGNYAKGCPCWQFNFKFNLNDDMFAQDSIDLLVTSGISFEDHATRGIDPLHFGELLMVSGLVLDDRVKWVSFHSGYDYAYLLKVLTTQELPQDEKSFFDVLKLYFPTIYDIKYMTSLLDGHFGGLQRLADDLNCSRIGPEHQAGSDSLLTMVTYFALAKAKFSEKSTGKIMDKKYKNELYGYGSNHTVQRKGIRSSDSSNVLSNNSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1GY48</accession>
    <name>A0A8K1GY48_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Cytochrome b6-f complex subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">17 kDa polypeptide</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14 17" type="primary">petD</name>
        <name evidence="16" type="ORF">QTG54_017194</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="17"/>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2021" name="Front. Plant Sci." volume="0" first="0" last="0">
            <title>Chloroplast Genomes for Five Skeletonema Species: Comparative and Phylogenetic Analysis.</title>
            <authorList>
                <person name="Liu S."/>
                <person name="Xu Q."/>
                <person name="Liu K."/>
                <person name="Zhao Y."/>
                <person name="Chen N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CNS00100</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 14">Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12 14">The 4 large subunits of the cytochrome b6-f complex are cytochrome b6, subunit IV (17 kDa polypeptide, PetD), cytochrome f and the Rieske protein, while the 4 small subunits are PetG, PetL, PetM and PetN. The complex functions as a dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="14">Plastid</location>
            <location evidence="14">Chloroplast thylakoid membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Thylakoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the cytochrome b family. PetD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MW679506">
        <property type="protein sequence ID" value="UAM91396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_010200907.1">
        <property type="nucleotide sequence ID" value="NC_058701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1GY48"/>
    <dbReference type="GeneID" id="68637924"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008121">
        <property type="term" value="F:quinol-cytochrome-c reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009767">
        <property type="term" value="P:photosynthetic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00290">
        <property type="entry name" value="cytochrome_b_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.980:FF:000001">
        <property type="entry name" value="Cytochrome b6-f complex subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.510:FF:000002">
        <property type="entry name" value="Cytochrome b6-f complex subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.980">
        <property type="entry name" value="plastocyanin oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.510">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01344">
        <property type="entry name" value="Cytb6_f_subIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005798">
        <property type="entry name" value="Cyt_b/b6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036150">
        <property type="entry name" value="Cyt_b/b6_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005870">
        <property type="entry name" value="Cyt_b6/f_cplx_suIV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048260">
        <property type="entry name" value="Cytochrome_b_C_euk/bac"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01156">
        <property type="entry name" value="cytb6_f_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19271">
        <property type="entry name" value="CYTOCHROME B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19271:SF41">
        <property type="entry name" value="CYTOCHROME B_B6 C-TERMINAL REGION PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00032">
        <property type="entry name" value="Cytochrom_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000033">
        <property type="entry name" value="B6f_17K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81648">
        <property type="entry name" value="a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51003">
        <property type="entry name" value="CYTB_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 17" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="8 14" id="KW-0249">Electron transport</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 14" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="6 17" id="KW-0934">Plastid</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 14" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b/b6 C-terminal region profile" evidence="15">
        <location>
            <begin position="65"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00060385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1732151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UAM91396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="160" mass="17753" checksum="31EB006541DDAFC3" modified="2022-08-03" version="1">MSIIKKPDLTDPKLRAKLAKGMGHNYYGEPAWPNDLLYLFPVCILGTFACCIGLGVMAPTQMGEPADPFNTPLEILPEWYFFPTFNLLRILPNKLLGVLAMAAVPAGLITVPFIENVNKFQNPFRRPIASLVFIFGFIFAVWFGIGACVPIDKAVSLGYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRL0</accession>
    <name>A0AAD8XRL0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD and tetratricopeptide repeats protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_016903</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000067">
        <property type="protein sequence ID" value="KAK1732422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080008">
        <property type="term" value="C:Cul4-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045151">
        <property type="entry name" value="DCAF8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15574:SF21">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15574">
        <property type="entry name" value="WD REPEAT DOMAIN-CONTAINING FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1252"/>
            <end position="1285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="26"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="160"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="343"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="562"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1300"/>
            <end position="1324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="61"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="160"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="198"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="246"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="274"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="310"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="344"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="569"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1302"/>
            <end position="1316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1732422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1324" mass="146197" checksum="810BCFCB69A32473" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRR1</accession>
    <name>A0AAD8XRR1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_017023</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000076">
        <property type="protein sequence ID" value="KAK1732288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRR1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1732288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="324" mass="36527" checksum="590F7B133A6A3BD5" modified="2024-05-29" version="1">MDHADEGDDDIFVYTGGQVPEHLKLLITHARIDESVDAVDDFAFNNCHRLLSVEFHVGIERVGVRSFAFCVSLRRMRFPGVQRIACQAFTSCRGMTDVEFGAYLERIEAGAFHNCTSLRSIFIPSIQIIDRGAFIICEQLTEAVFGEELREIHSLAFFSCLSLRRIAIPLKNGMLNDQSERGHEYRAFKDCVNLTTVDLVGGVHKTISSLHMQSWRNEMKHLIGLINHVLPRTVALNKTDAIEEWIGIVLRRINFYKAEHHTLLREAMSLLELAVWKAKLGEVDEVGRAKGADTDISNARRKESRVKSGASVVVKNVFSFLVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRY4</accession>
    <name>A0AAD8XRY4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000065">
        <property type="protein sequence ID" value="KAK1732518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRY4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042173471" evidence="1">
        <location>
            <begin position="19"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="204" mass="21198" checksum="1F4038C7FCEA0211" modified="2024-05-29" version="1">MALCQLFVAIASFLAAVAVNSNAADVGNVLPTCESVNATDTNCKVYCRDNGYDTTLDGSVGGSVYDEYENSWTGVGSHSCLCKNMGSFDMTTVCQTIVSTASPTATPVPCNVSDFEAVRADDGSLPTCASMGITKITCHEACRACGDNGSTWSWGVSDSIGRCECGTFDSDIYWLCADQELPSGASASSGFMAISVTLFAAVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSS5</accession>
    <name>A0AAD8XSS5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000053">
        <property type="protein sequence ID" value="KAK1733176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSS5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="90" mass="10078" checksum="6AB36B21DB795D8C" modified="2024-05-29" version="1">MTTNSKGNASAAANCVNVPTKTHDGGAKAAANDSEPAAKRPRQQQPVHKHQDPFLYYSDQETRMNECILLALKEDWQEEDIRKELGGYKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSU7</accession>
    <name>A0AAD8XSU7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016554</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000058">
        <property type="protein sequence ID" value="KAK1732751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSU7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="153" mass="15966" checksum="F57BD577B3C43E7B" modified="2024-05-29" version="1">MQTQIPSGAHNDEEAFQPPEMNLANEADENNDEAEADVEPRYGYWSSNKNKCLAALILAATIICVLAAGGSIKTAYDSKRSNAVGLETAYGNYGPVAATSAKSSKTPTSSSKATKGKSSKAPKSKSSKAPKSKSSKAPTSAPVRAPVSRGRQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XT58</accession>
    <name>A0AAD8XT58_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015979</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000051">
        <property type="protein sequence ID" value="KAK1733262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XT58"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="1">
        <location>
            <begin position="67"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1036"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1036" mass="116546" checksum="0EBFEB265B18E526" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTI3</accession>
    <name>A0AAD8XTI3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015754</name>
        <name evidence="3" type="ORF">QTG54_015757</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000047">
        <property type="protein sequence ID" value="KAK1733581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000047">
        <property type="protein sequence ID" value="KAK1733584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTI3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="128" mass="14330" checksum="5B5CCC5CF3BB1041" modified="2024-05-29" version="1">MSSNYSSGLNIVKSSTDTHTNSYSECITNNDDNNEPEEYVTNFYRQKRLEKRELAAKTVARSNGGDPHLRSAADHSLDHYFDHHDAIARKSGHLDNNVNDGNSGSGDGDGKKRVFFRRNNISGQQLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTX9</accession>
    <name>A0AAD8XTX9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">AP2/ERF family transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_015959</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000050">
        <property type="protein sequence ID" value="KAK1733400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTX9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32467">
        <property type="entry name" value="AP2-LIKE ETHYLENE-RESPONSIVE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32467:SF90">
        <property type="entry name" value="AP2-LIKE ETHYLENE-RESPONSIVE TRANSCRIPTION FACTOR AIL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00380">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51032">
        <property type="entry name" value="AP2_ERF"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="164"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="249"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="330"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="585"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="700"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="429"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="657"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="24"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="438"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="657"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1733400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="752" mass="84963" checksum="C5124C58D0426640" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUY7</accession>
    <name>A0AAD8XUY7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Circumsporozoite protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_015435</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Essential sporozoite protein. In the mosquito vector, required for sporozoite development in the oocyst, migration through the vector hemolymph and entry into the vector salivary glands. In the vertebrate host, required for sporozoite migration through the host dermis and infection of host hepatocytes. Binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes.</text>
    </comment>
    <comment type="function">
        <text evidence="5">In the vertebrate host, binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes and is required for sporozoite invasion of the host hepatocytes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the plasmodium circumsporozoite protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUY7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051860">
        <property type="entry name" value="Plasmodium_CSP_Invasion"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44826">
        <property type="entry name" value="SPORE COAT PROTEIN SP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44826:SF3">
        <property type="entry name" value="SPORE COAT PROTEIN SP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0748">Sporozoite</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041978694" description="Circumsporozoite protein" evidence="9">
        <location>
            <begin position="23"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="39"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="183"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="44"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="71"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="200"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="222"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00033726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00045806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1733908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="238" mass="25795" checksum="825634401795C552" modified="2024-05-29" version="1">MMTPSLALVFIVCVVLPKAALGIPLPYYVYRAPPTSSPSALPSYQPSSRPSLQPTSNPSISPSHQPSLRQSSRPTSNPSFSPSNSYQPSAQPSLSAQPSLSVQPSTQPTSNQSSSSFLRTSNNWMKSDWMIISLIGILLCFVGIVFQLVRKKLQCLPCGAGGDDTSQNSLDMDDDYDTFDIHVSSNTARTRKPPPHRSRRNNDRNDIRRSSRSRRRDRCDDGGSVSGSSAASESSGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVI8</accession>
    <name>A0AAD8XVI8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015039</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000040">
        <property type="protein sequence ID" value="KAK1734272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVI8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="195" mass="22567" checksum="3BFF70DA71578473" modified="2024-05-29" version="1">MCVVVSPIPTRLYRRSASYPCNKRTATHSILQPPSAVQPPLKKKTTYHQQPAPPRQQRKQQRQHRVTFSTSSSLHIVTNLTFHYKHILWLTSEEIQRKKRKIELFTYLLKSKRIDKAEFDEVLLMGLEKHLHDDYDSSSNGSGSSRQELFAAVLNEQRRQGNFDIQDVEALAMISRGMSQRARDRARIIGVLQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVK9</accession>
    <name>A0AAD8XVK9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ZIP family metal transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_015067</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000040">
        <property type="protein sequence ID" value="KAK1734300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVK9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF140">
        <property type="entry name" value="ZRT (ZRT), IRT- (IRT-) LIKE PROTEIN TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1734300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="206" mass="22331" checksum="CCA6AEDE37CB0DFD" modified="2024-05-29" version="1">MNHSEPKRETEVSGEDQNSKKDGGDDEERDDQEQDDYVENEEHDHVHIIDAAKPLASILLTVALSIHSILEGIGIGATDNVSALQSEFVAVVFHKGFTAFALGNQLVSSGYWTDKSKRKYFYISIGTFIGVSLLGIGIGWAISYANSGLTAAIFVGITSGSFIFVSALEIIPGEARIIKGERLAILPVVFCFIAGYMLMAMLALWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWC7</accession>
    <name>A0AAD8XWC7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_014784</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000038">
        <property type="protein sequence ID" value="KAK1734536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWC7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="315"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1734536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="434" mass="49601" checksum="1D6BAA232B5A432D" modified="2024-05-29" version="1">MFGSISGSIDPFGRRNSSSDTWLPERRARYNAKRRQKDLELIFTIWNEALPNAGDAVIHIADAPASTVKKYKRAVNVHRKDLMRVDLQWQKEWNQYHEEGRTVFRADGSIVRTSCDKMVPHSFKMLRLLKERIPTHKSKVISDLPLNFRDSYDGWYDEGDKGVTTLHFWMNYRIGNSFLNDRNKDFESGLDYIDRALSLIPPLREGDIPHENEIMARIFRARALQNLGDISRALAEYRVCLAAIRLLDYHGKVDMNKSKDILISKTTNFTSIIIGLAIESKVQEGANRPYFSHDERLDLMKELGYGMYSDNSLKCGCCGKTDLELAKLKKKLVLCATCKGVWYCGRECQKEAWKKGGHGKICGKTPGVQTKQVSFASYAQLISGGLCFYRDKHDPSILVFFKDKSTDQTFDALTDQEYEIEVDDSRDTSTVAVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWG2</accession>
    <name>A0AAD8XWG2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Palmitoyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_014625</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11 7">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWG2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12246">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="8">
        <location>
            <begin position="200"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1734752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="394" mass="45482" checksum="B4A632E905C0C907" modified="2024-05-29" version="1">MRLLTPGSKLQRTWSDFIDALYAPVGQDFNALYWLYRLSSALLDTILPCRDDLRRIRINGFACRLRPLIPCAGITLTLLCVISYFTTFRDTAVIKKGKSETLHTSIVVWLAFNVLSHYLYCIYKSPGIVISPKSEMTANINASVAKRNDAVIKIGGCCFIQSRVNINNEKKRCNFYEHYCTTNVKIDESTQNAVHHPMPNDTFCHKCEINRNARSHHCRVCKVCVLEYDHHCPWINGCIGYNNYRNFVLLIFYIMLGCWYGACLLALDFYAMMREYFQDNGFKIMGPQYGTGILDLPPPWTLLKDYRNTGKIDDDVILRAVFPFLLFVSICMFVFLLDHLLSIAKGFTTLEKKTRPDRNDVVNPFDLGIRKNFERVFGKSLINIIIPFPTHKKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XX10</accession>
    <name>A0AAD8XX10_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aspartate--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_013649</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>tRNA(Asp) + L-aspartate + ATP = L-aspartyl-tRNA(Asp) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19649"/>
            <dbReference type="Rhea" id="RHEA-COMP:9660"/>
            <dbReference type="Rhea" id="RHEA-COMP:9678"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.12" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XX10"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017101">
        <property type="term" value="C:aminoacyl-tRNA synthetase multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017110">
        <property type="term" value="F:nucleoside diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04320">
        <property type="entry name" value="AspRS_cyto_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00776">
        <property type="entry name" value="AsxRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000013">
        <property type="entry name" value="Aspartate--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.100">
        <property type="entry name" value="Apyrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02075">
        <property type="entry name" value="Asp_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009283">
        <property type="entry name" value="Apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036258">
        <property type="entry name" value="Apyrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004523">
        <property type="entry name" value="Asp-tRNA_synthase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="uS15_NS1_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000738">
        <property type="entry name" value="WHEP-TRS_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00458">
        <property type="entry name" value="aspS_nondisc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003483">
        <property type="entry name" value="PRK05159.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450:SF1">
        <property type="entry name" value="ASPARTATE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450">
        <property type="entry name" value="ASPARTYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06079">
        <property type="entry name" value="Apyrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00458">
        <property type="entry name" value="WHEP-TRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00991">
        <property type="entry name" value="WHEP-TRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101887">
        <property type="entry name" value="Apyrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="S15/NS1 RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51185">
        <property type="entry name" value="WHEP_TRS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WHEP-TRS" evidence="14">
        <location>
            <begin position="321"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="13">
        <location>
            <begin position="622"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="368"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR609283-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1735486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="928" mass="104360" checksum="5FAA7856B0B64C28" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXI6</accession>
    <name>A0AAD8XXI6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Copper chaperone Cox17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_013864</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COX17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXI6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016531">
        <property type="term" value="F:copper chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1130">
        <property type="entry name" value="CytochromE C oxidase copper chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009069">
        <property type="entry name" value="Cys_alpha_HP_mot_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007745">
        <property type="entry name" value="Cyt_c_oxidase_Cu-chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16719">
        <property type="entry name" value="CYTOCHROME C OXIDASE COPPER CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16719:SF0">
        <property type="entry name" value="CYTOCHROME C OXIDASE COPPER CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05051">
        <property type="entry name" value="COX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47072">
        <property type="entry name" value="Cysteine alpha-hairpin motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4 8" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR607745-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1735250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="69" mass="7366" checksum="ED7FEF933C4ED770" modified="2024-05-29" version="1">MGNSASAPATPPATQKVGIKSGKKICCCCPETKQARDACVLANGEDDEDCKRLIELHKECLRGEGFDVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXU6</accession>
    <name>A0AAD8XXU6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXU6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042002017" evidence="2">
        <location>
            <begin position="18"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="125" mass="13554" checksum="0A8F541AC9D2D28B" modified="2024-05-29" version="1">MMKLLLLTLPFLPFLEAFAPCPSRSGVASFSPRSLGVDRHLQLQLPVLNMKIDEKRRKELGLPEDADEYDLDVALNNNTDAGITKIIAGSFILVMLALLVVGLVIPSITDYGDGVCSPIQNGGRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXY1</accession>
    <name>A0AAD8XXY1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXY1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="84"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="135" mass="15337" checksum="9B792A445F156A66" modified="2024-05-29" version="1">MAPEQIKEEANPISSVYAESHTEEETEWLSMGLSLGDALRQIVALTDERDSALAICQEKDDVATQAESLLVEVQVRLEAEMNRRAESDSKARKLLETMKAYEERLESYEKMEDELEAAQANLVTTVSEKSKLEWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XY63</accession>
    <name>A0AAD8XY63_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013629</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XY63"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032801">
        <property type="entry name" value="PXL2A/B/C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13911">
        <property type="entry name" value="AhpC-TSA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="233" mass="25803" checksum="5704E724238D81D8" modified="2024-05-29" version="1">MLVLGTYAADFNAVEYAQRLRYYMPELQKRGISKFGIVLNCEADAALKSVTLMIDPMGQAGRKFGVGTGWRSDDEEMSPYLKLFGMLFGLGAWATLPAVIGGYIGNPFTAQPWIEDAMAVGIRKKRWPDNGLELNDSGDVVVNKFQELPVVGEWKRRPLELATLRLQNMIDISIKNWKELAPKDDALKAGVLTQLGGCVVFDSTKDAVVFEWKDPGICAVANFENILEKVPVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYQ3</accession>
    <name>A0AAD8XYQ3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rad60/SUMO-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYQ3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01763">
        <property type="entry name" value="Ubl_SUMO_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022617">
        <property type="entry name" value="Rad60/SUMO-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11976">
        <property type="entry name" value="Rad60-SLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad60/SUMO-like" evidence="1">
        <location>
            <begin position="2"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="49" mass="5521" checksum="20ECD950647D0778" modified="2024-05-29" version="1">METLFQAFASKKDIDVSNLRFTLCGETIHPSASPESLDLYDMVEIEAAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZS9</accession>
    <name>A0AAD8XZS9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012386</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZS9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1736941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="202" mass="22107" checksum="339D8B52C4855541" modified="2024-05-29" version="1">MRLDVYVSMSRGDGGRWIFANPRLRPDGKGGFVGTMIPKAYNGGTGCRDTSRPVIELMGPNPKVFRVAKTSCLKGVVKGANDNADANARVDAILAEQRTTYEKDIKYMIVATSGAELCATSTRPNVRPMDCIRAKDHTYKGVVDLTARVSVGEPIHDGAPLRWKVPYNVMDDAGNKAKTVWRSIIVEEVGLDEFESSNEQPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y047</accession>
    <name>A0AAD8Y047_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidoligase enzyme-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013086</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y047"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022025">
        <property type="entry name" value="Amidoligase_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36847">
        <property type="entry name" value="AMIDOLIGASE ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36847:SF1">
        <property type="entry name" value="AMIDOLIGASE ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12224">
        <property type="entry name" value="Amidoligase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="496"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="496"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="513"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="537" mass="60882" checksum="F601D79A8FA92D44" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0A6</accession>
    <name>A0AAD8Y0A6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0A6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="430"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="510"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="534"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="589" mass="64915" checksum="6EAB22199213575B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0C9</accession>
    <name>A0AAD8Y0C9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_012643</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0C9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051637">
        <property type="entry name" value="Ank_repeat_dom-contain_49"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24180">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24180:SF45">
        <property type="entry name" value="POLY [ADP-RIBOSE] POLYMERASE TANKYRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="242"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="530"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="249"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="541"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="557"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="581"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1736621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1238" mass="138035" checksum="E3CAF252AC30885F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1G3</accession>
    <name>A0AAD8Y1G3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000024">
        <property type="protein sequence ID" value="KAK1737657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1G3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="297" mass="34156" checksum="C92B725B90A42640" modified="2024-05-29" version="1">MATLIDSVIGNDDISFHIASFLCPRRNPSTLTEFYSNECFVSKLWNNAFGLVRAQLRWDFLRKQLKQDEDNGWLYHKLVYIPKGSAIPDGGGKDKQIPHEGMIRIFRSHVNDTCFQSLKDFQSSRQNDPHGEHIRADSRPDYYYRTYKETAQYIDLIPPRALTWTYDTTIIIENDIEYDEKPRLVNEFIAFLDDVTGASGSLVQEKSSEGRWNLGYHEIVNVRDSTFSRIHPRPPHKGHGTETTNFLSVLKAKSSMLGPRRVKFAHLKGDDECRTFIRKHLLPIIGPRPSGTNGNNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1J5</accession>
    <name>A0AAD8Y1J5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heat shock factor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_012058</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1J5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000479">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF206">
        <property type="entry name" value="HSF-TYPE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="5">
        <location>
            <begin position="35"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1737191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="225" mass="25014" checksum="8BAF14F43C89732E" modified="2024-05-29" version="1">MSDAALLKIMTSQLPSQNILPPLSKGGKRGPRGGVYDPFPIKLHRMLDEVRAAGLESVVSWLEHGRAFRIHQPKVFAATIMCRFFNQSKYTSFQRQLNLYGFSRCVRGPDGGAYHHPSFLRGKAALALNIIRTKIKGNGHKTMAPLEEQPDFHKMVPLKNEAPPVCLPKTHPLMAAPVSPTPSSRSSFSSLDGTHLDEINKSIFMHELAMGCTILCKLRQDDRTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y278</accession>
    <name>A0AAD8Y278_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011664</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000024">
        <property type="protein sequence ID" value="KAK1737680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y278"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="50" mass="5552" checksum="EC088E09A5AD7BD6" modified="2024-05-29" version="1" fragment="single">SIHSHLLSSASLNSTNHTSIPRPLLSIRQVCHCIGIRRNKFTSGFSLIHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2A7</accession>
    <name>A0AAD8Y2A7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010993</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2A7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051144">
        <property type="entry name" value="Formin_homology_domain"/>
    </dbReference>
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        <property type="entry name" value="FORMIN-J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="279"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="328"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="418"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="453"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="506"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="534"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="196"/>
            <end position="225"/>
        </location>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="701"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="836"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="100"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="726"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="752"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="767"/>
            <end position="777"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="895" mass="100431" checksum="8060972787F678C7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4N4</accession>
    <name>A0AAD8Y4N4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4N4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="109"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="281" mass="30911" checksum="56C30723CA7057C7" modified="2024-05-29" version="1">MNDLLGHELRKALSDPSNYGSGSRKNEQAGAAAASTGDLFDDWVNEVEPHGMVSTKEAKKEYFLTADDLATLSYESYGGGIGCGPPTKCYVHKDLVKTSLRKHGRAGVVKKLEARHKREEKKRMKEEQAEQARKRLKTITNTSADGAAAATATTMKASAGDTQEVKRLREGLLKMVKQNMGFEMSGAPKNWRIEVPGTSKATFAALVGRHIDVDLDSFVKKGAYYTEQYEASKLLGTYEAQLIKDFNREGVRQEIGSTVTVRYKPSTMELSVSGHAELLGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4P6</accession>
    <name>A0AAD8Y4P6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MAP3K-like serine/threonine kinase</fullName>
            <ecNumber evidence="3">2.7.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009955</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4P6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050167">
        <property type="entry name" value="Ser_Thr_protein_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257">
        <property type="entry name" value="SERINE-THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="301"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
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        <location>
            <begin position="127"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="617" mass="69625" checksum="8B84DE6573CC517D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4S8</accession>
    <name>A0AAD8Y4S8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dienelactone hydrolase family protein</fullName>
            <ecNumber evidence="2">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4S8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630">
        <property type="entry name" value="DIENELACTONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630:SF44">
        <property type="entry name" value="PROTEIN AIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="53"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="289" mass="31585" checksum="A0B11E8D0BE23FAE" modified="2024-05-29" version="1">MTTSCCPDNSWGSPLHVSHGTKSLDGARGELCKIGPSKDLEMYVSRPPVGGASQKALCVLTDVYGLQSRLFAICDKLAADLQLTVVALDTFRGETKDMHLDDFKEWLGSHPFERDISESAKDDKSAVYPVKEDIESCFEFLLDTYNINSSDVGVAGFCWGVWAMTKACEMKLFRCAVGFHPSIKIESMVFGGDQEAITKKAADNAPILLCVAGNDLDNLKPSQGGALANIIAKSKTKDTGDNDKAAPRCVEFPEMMHGWVSRGDTSIEKVKEDAEAALNLSVDFLRRWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y510</accession>
    <name>A0AAD8Y510_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin-associated domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009351</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y510"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000058">
        <property type="term" value="P:regulation of ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039749">
        <property type="entry name" value="NUB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12948:SF3">
        <property type="entry name" value="NEDD8 ULTIMATE BUSTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12948">
        <property type="entry name" value="NEDD8 ULTIMATE BUSTER-1 BS4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBA" evidence="2">
        <location>
            <begin position="579"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="623"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="696" mass="76384" checksum="F6DDD23DBC75F65E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5H0</accession>
    <name>A0AAD8Y5H0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009026</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5H0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36970:SF1">
        <property type="entry name" value="BESTROPHIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36970">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="108"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="388"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="485" mass="53962" checksum="3F0A8F4E3C4685B4" modified="2024-05-29" version="1">MHASYGIRSAKIMSDGEHNSMKNVVFEEAASPASPPSSGADSSATSPLSTTTAISTSPYLHKVTTRRHEFLHESQTNNNLLESNALKISSHKSKVFVFLWDLYSAFRLFGVLLISMETFVGCALTIGATLLAYYMSPKVAVSEEQWDGTLPTILLSFATVTPLIQSISMAFNRREAALRGLASYRSAMYHIYMAQASWDWGECGKKGGRRSCVENTDDLKSVQEVEEVKEGGDGSEEDTTTLPPKPIDWINHADNLLCQLIHLSDSLSHYLALPTASRTHHRATKLGEREAKTLVFTGRKIFALNAAGRIFMISQLTEALKYRGLPGNEASRIRQWEQYLSVSMENMRLIKEYRTPQSLRLFGRVFTLLLPPLYATSFAQTAIDTESIVFGCIIGAVTSLALTSLFEAVRQLEDPFARGFTFDGIDVTEELQVLAYEELMVARSMVFPDAEEFVLKEDTKAKKAVGLDRKSRHYCEDCARIIKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5L3</accession>
    <name>A0AAD8Y5L3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009987</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5L3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1739444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="515" mass="58256" checksum="629684408A142AE6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5Y7</accession>
    <name>A0AAD8Y5Y7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009479</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5Y7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021466">
        <property type="entry name" value="Put_rhamnosyl_transferase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11316">
        <property type="entry name" value="Rhamno_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="189"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="385" mass="43295" checksum="E71413E355723097" modified="2024-05-29" version="1">MVAAASSPQRMAMAPPAASTRGRLHRQIYIVIACALGLFVTSTFILSTYIPSPTEFHSHDNNNAAFHSVAHIVHRHQLHGHHFVEPKGHLRRKNDMRYAREEIITTESSKSAHEDDNREEDDSNDDGDKSDNNDDNKEADDEAGDQEEVPHYIENDDMDRQGNSESESGDAEEGEGSSSDNDDNEGVENEMQGDGSSSDNDDNEQTENALQEGGSSSDKDVNERTENNELQEDESSSDKDDDDKTELQEEATSSDKDDNERIEISPRQKMQSQDEVQAEDEHQSQTITDTTDEKKEPPQIFHILETRFMQNQPDLVELAKARLQLFEAICLPTVLQQTAWGNFLWIIRTDPDLHVDIRRELVEMLNERGALTTKRNDTDGTGSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6R4</accession>
    <name>A0AAD8Y6R4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009158</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6R4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="188" mass="20950" checksum="BBAA0EF4F8109DEA" modified="2024-05-29" version="1">METSFETLRGEDIEESSGQSSKLADPNGVRAAELASNRDAGRKKEEELADSPHRHDPDGHLILSDIYKAAKKSRWEREEKSQISAPSRQVSAPTQTLNDKVAKDLRVHRAKMNSFLDEDTEPELGRGATSSSKIFNPLSLPQRQRIPRILEDDDSDVLKDFSFAHSVQDDDSRATSIKEEVCSPTSVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y768</accession>
    <name>A0AAD8Y768_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Drug/metabolite transporter (DMT) family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_008543</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y768"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051258">
        <property type="entry name" value="Diverse_Substrate_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42920:SF5">
        <property type="entry name" value="EAMA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42920">
        <property type="entry name" value="OS03G0707200 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042181793" evidence="6">
        <location>
            <begin position="26"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="7">
        <location>
            <begin position="159"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="7">
        <location>
            <begin position="395"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1740448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="488" mass="52728" checksum="60C77EAA5DCAE179" modified="2024-05-29" version="1">MAVQCSIKATIVGLLLLPITSLSFSRSPTASFVSIPRSSYLTTNTLAASREALQGDHFIARNGTSDVLTYQNVGSGLQTDDDDETTTFLERELLEGYMAHQQLLLDAEDDADADEESVTFYEEPQVLTTSSYTTTASVDSVRNNLPKSFILSDVWKARMLLLLSAALYGTNFSVVKQLDEIMPVGVSSTLRFGLAAFAMLPLLIAPLSEEFKNNVKNTASKTTYAFMEPSRLSVGLAGMEIGLWNSIGYISQAIGLRTTAASTSAFICSMAVVTVPMLDYIFGRPLLRRQIVGAALAAFGVYALEMGQDISSFTSDDMASLVQPIMFGLGFWRMEAAMEKFPTEAARLASGQLFMVFLVSLSYLVCWSPAGDDLMIQDACNVIPTMGDIAAWLSDPSILGMLIWTGLITTAFTIYMETLALKTLSAAETTLIFSTEPLFGAAFAAVVANECLSEGGYIGSALIIGGCVISGIDWSQHFRRHGDIQESN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7E1</accession>
    <name>A0AAD8Y7E1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009066</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33683">
        <property type="entry name" value="1, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33683:SF46">
        <property type="entry name" value="SUSHI DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="741"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="856"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1033"/>
            <end position="1429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="171"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="745"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="765"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="788"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="863"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="896"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="912"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="937"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="957"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="980"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1050"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1074"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1090"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1183"/>
            <end position="1203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1222"/>
            <end position="1234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1240"/>
            <end position="1251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1275"/>
            <end position="1295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1310"/>
            <end position="1326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1330"/>
            <end position="1350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1361"/>
            <end position="1378"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1429" mass="156320" checksum="459788A61FDE2A56" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7T1</accession>
    <name>A0AAD8Y7T1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008682</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7T1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032801">
        <property type="entry name" value="PXL2A/B/C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13911">
        <property type="entry name" value="AhpC-TSA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="152" mass="16871" checksum="B7CB3585BABBA4C1" modified="2024-05-29" version="1">MGIGGPIFVSIGDAVKLNTFLDANPWMPRSQMFVDDYSFDTYKAVGFGRFDEVDKESDAIKNFKMTAPELGFKEWMNYFGVVNKVSPIPKDMKFGEFPEGVLRTGGTFVVQGDDVVYQWTDTIPGNHPVIEDVVTIAKNAAKTPAGKKGSWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y813</accession>
    <name>A0AAD8Y813_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleotide exchange factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y813"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050693">
        <property type="entry name" value="Hsp70_NEF-Inhibitors"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19316:SF18">
        <property type="entry name" value="HSP70-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19316">
        <property type="entry name" value="PROTEIN FOLDING REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="627" mass="69149" checksum="46093AC3A0EEF050" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9C6</accession>
    <name>A0AAD8Y9C6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribosomal-protein-serine acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007845</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9C6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990189">
        <property type="term" value="F:protein N-terminal-serine acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008999">
        <property type="term" value="F:protein-N-terminal-alanine acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051908">
        <property type="entry name" value="Ribosomal_N-acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43441:SF2">
        <property type="entry name" value="FAMILY ACETYLTRANSFERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G00850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43441">
        <property type="entry name" value="RIBOSOMAL-PROTEIN-SERINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="430"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="464" mass="52266" checksum="92346C06218C9CA8" modified="2024-05-29" version="1">MASTTTIPSSELTDLQKLLNAFSHITSITSPTDILAAFGLLDMPAAQKYGIIFGCLTFTITVIAVISLLYLGGSFKRIEEQAKSGELVTAPDSVTQRRRRPLLLERLLEGREWMMQTNYGGQLNSSTKKDEYTNLTKMLMTTAPSDKSEMSKEYEENYIKAYKRCQDKPGGAILGGRPNHRFEAYARAFAGCGSRTSLNYRWSYARMYESMAGESHKSDERYESLYKERPHDIIGKTCRLEPLLASRHSKELWEITSGNACNEHKAYNPDEVWGFLDCGPFKNEQALKESDVFQLEHTAAGFAIVEFVTDRLVGVVHLSKDDPKNLSVQLDLPIVKPTSDGSIEQLEACFLLLDRLFAYGYRRIQICVDALDVRGKRLPQRLGFTQEGQIPKHMIVKDANRDSIIYGMLNSDWDKGARSFLLKKLHGAAFEKADAAIVAKEEAVEDQEQKLREKKEAEAKANTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9U9</accession>
    <name>A0AAD8Y9U9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Chloroplast protein import component Tic22 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_007282</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9U9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007378">
        <property type="entry name" value="Tic22-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33926">
        <property type="entry name" value="PROTEIN TIC 22, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33926:SF4">
        <property type="entry name" value="PROTEIN TIC 22, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041950899" evidence="5">
        <location>
            <begin position="20"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="324"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="328"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1741709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="382" mass="41729" checksum="74D4BD42B859F3C9" modified="2024-05-29" version="1">MLHRVILVSCILFVSSVVGSSSSSQLSAAIGSSSQAALFGVRGGAFFGFGRKQSNNGDGDDDDNNNNTPKRFPPMSQQEIEEKLNIPVFGLTDAQGNGVILSDNGNNIFHFFFSKHMADAALKAVTAANAEAPELRVSAFHLGKCWFKLIQGHKMFELRKYGKNKGDDTTTSTKPVQFRLVPNSKDLMGARILTGLKPGDVDELKEAIETPDAPKAVSIIQSAANDANGFTNAFNEIPCFAISQMRVRKKNEAGEPIGEPMLPFHLSTKTMGDTWSEFTRHAPQFEDAEATLQLVELHKMIEMMQNPSDFDFRNIVFIVPAYDQDLPNNDDTDDSDSDDDTGGGDNGMTADSGRSYNECEIEPYVSMEVFADAPGYNSLVQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9Y1</accession>
    <name>A0AAD8Y9Y1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-lactamase</fullName>
            <ecNumber evidence="4">3.5.2.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006797</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.6" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9Y1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008800">
        <property type="term" value="F:beta-lactamase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050789">
        <property type="entry name" value="Diverse_Enzym_Activities"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283:SF7">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041990855" evidence="2">
        <location>
            <begin position="24"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-related" evidence="3">
        <location>
            <begin position="65"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1742232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="410" mass="44703" checksum="ABBFBD439445518A" modified="2024-05-29" version="1">MISKTSASITALLLLQLPTSTLSSNTPRIIDLSQDIPQDKAAMTSSPGASAIQQAAAKDPLIRAAIVLEHGDIVASYHRDDVDLNETTFMVHSTTKSWTSLIMGMMVEDGLLSLDETLGDIFPNDEAWADVTDGSTEFRKNVTVEEMLTMTSGLITTLDSMWDPSWGGSSLEDSLSYPEIGVKGEFSYLVVSNIPSYIIKERSGINPRQYLAERVMDKLGIGEDEYDWQQNDDGVEFGYHGLLLTPNQMAKFGQLYLQGGRIDPSNDERLISQEWIDASFTQHATEDDFGLPYGYLFLGMGEAYCSLGLGGQDICVDRDLGRVVIQQRDLDYGAMDDMQGLEHLVVAPVALNGSNSFRAASDGVNDAVTSQPKEDGEQVASLSDTSGSVHLLATSMWISMMGLSVLVAMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAM5</accession>
    <name>A0AAD8YAM5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_007414</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAM5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1741841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="333" mass="36986" checksum="6F99FF58E065E125" modified="2024-05-29" version="1">MVGHSVLESVHALLPLSELQSSSNNAISNAFDTARCAFDDIECGDDCSGDGALMPLIDPSSDSGGWTGYHKASHLNGRYNQHRQGFVFSNGEFFNLHSNVDFESDMKQFFHFSHDVVASGVLKAIERRLELPDCYFDNELGPTDNSSQWHLKQYQVDELDEHSNDTPPLSQQHDQKVLLPMHTDPSLISVVIIDSPGVNKGGKGLEVFQANSSEDAVPNDCKTKHSRGIWKAIPHHGRDVAIIFVGSVLSYLTKGQVFSAMKHRVVDDCKDDINDRMAATLFVRPQPGAYMKTLPSKYIEHGGASSTKLPPTFRVWNARVAKNYMKKKKKQKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAN2</accession>
    <name>A0AAD8YAN2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Polysaccharide pyruvyl transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAN2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007345">
        <property type="entry name" value="Polysacch_pyruvyl_Trfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04230">
        <property type="entry name" value="PS_pyruv_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Polysaccharide pyruvyl transferase" evidence="1">
        <location>
            <begin position="108"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="394" mass="44048" checksum="1279B379C40A713A" modified="2024-05-29" version="1">MFEGGTVSVGIEVKIVERKSIAIQGWYQPSTHAVRLARSTDQNSGNFIWEFGATRLINPYTTKFLNPSDARKESVNVDALVMASANALHLPDLDSESFRVMKDHVNGLSSLVKEIDRPTIMLGIGIQAKFSDIKDTKHIALHEHQAHLMNEIAKRNTLEKSVSVRGEFTETACINAGVHNCLSMGCPSLSISRERNLGQLLGSKWSAVESKLAHDNSTLKIGIGLPALHDDNMKYPKVVDLLLAICENHDCHFIVQAPYDKNLLLKHAGDKVDVNNVHHFKGGVETWFQFMHQLDFVVSTRIHGGMAGIVNGIPTIIIPTDLRILELINAMKLPYLSFEDVMAKKFESLQAIMGAAKKDFIDFEQNRLNRLREYKRMLESVGLEMDPLLLDIIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAQ6</accession>
    <name>A0AAD8YAQ6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007693</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAQ6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="252"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="206"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="252"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="316" mass="35098" checksum="2F322CEA8825C0E6" modified="2024-05-29" version="1">MKYSTAAVILVTASSSPQLSDARAYIFAHMNKCVKEHSTRIDSSLYAGYCVGCSNWKNDLRSEPLNECEVNRRPSSAAHDMPIRRVIRQSPEPVDELPMQMTELEQYTSPTISLSDSTDITDELIRTVKDNMEDDSHDDEDHSFVRQLIACLLLFGVTATAYLSNNTEKRKTFNVRTPKEGLKIVISTDIPPSLAPASPLSMDDSLPESEAEISKLREENQILQDKLAATEQSFNQSMTSSEKDALHNIINATHNIGSPNPSDSKGKEQSLDDFPGSSTTNAASTIQTLHNQIEDLKEELKLTKECLHNAIKHCSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAX1</accession>
    <name>A0AAD8YAX1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ABC transporter, ABC-G family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_007690</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="554"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="581"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="623"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="663"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="698"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="769"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1182"/>
            <end position="1202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1214"/>
            <end position="1240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1271"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="192"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="833"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1742117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1327" mass="147106" checksum="7ED01FB59DA81369" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBH5</accession>
    <name>A0AAD8YBH5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006684</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1743087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBH5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="265"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="638"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1743087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="701" mass="77752" checksum="39D5D0226AB6688D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCU3</accession>
    <name>A0AAD8YCU3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MBL-fold metallo-hydrolase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005728</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCU3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42773:SF1">
        <property type="entry name" value="METALLO-BETA-LACTAMASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42773">
        <property type="entry name" value="METALLO-BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13370">
        <property type="entry name" value="Fer4_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042133663" evidence="1">
        <location>
            <begin position="29"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="2">
        <location>
            <begin position="169"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="407" mass="44886" checksum="5DEC0C3044D1D339" modified="2024-05-29" version="1">MKSSLFVLRSGAALHLVLLGSVTLPAASFSCISRIRTLSSAHSQPLRAAPQRLDENVQGILYVNDRCINCAACSNFAPNVFERGSKLKHIVYKQPTVQNKNELEEARAALAACPVAAIRVESKVTDSDAELKRALSIQPNGDALFPRQIISEIDLGVFYLGHHNEASFGAIPYLVRGKSPYGIDISVMVDVPRFSRSAVTAVKSLSPSGPDYLFLTHVDDTADHNKWVEEFPTMQRIFHAGDLGRHNWIGDTTLENVEILLKGKVEDGAKELMIWDINGNQMDEMQPLQEEEILILHTPGHSPGSISLLFRPKSDSVHNCNGILFTGDTYSWTTRDGGHMSGFPRYGNDLPEQAQTLKLLGELSHMWDIIAPGHGHLRSYTTLKGEENESKTKGDDIDIAVSELLSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD35</accession>
    <name>A0AAD8YD35_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Exonuclease mut-7 family protein</fullName>
            <ecNumber evidence="6">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_004782</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD35"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051132">
        <property type="entry name" value="3-5_Exonuclease_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620">
        <property type="entry name" value="3-5 EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620:SF104">
        <property type="entry name" value="EXONUCLEASE 3'-5' DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="62"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="99"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="3'-5' exonuclease" evidence="5">
        <location>
            <begin position="573"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="215"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="229"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="743"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1744249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="743" mass="83331" checksum="3991AF83562E5CC5" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD50</accession>
    <name>A0AAD8YD50_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004809</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD50"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37494">
        <property type="entry name" value="HEMAGGLUTININ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37494:SF1">
        <property type="entry name" value="STAPHYLOCOCCUS AUREUS SURFACE PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="724" mass="81900" checksum="47CFBC79D45683CD" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDX0</accession>
    <name>A0AAD8YDX0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_006067</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDX0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF3">
        <property type="entry name" value="HALOTOLERANCE PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="32"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="79"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="243"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="255"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1743446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="310" mass="34080" checksum="EB8EAED7CF8332B6" modified="2024-05-29" version="1">MSQGKSTIPDIHRGDGDGDGKNKSKDQTLCSSCDSCRAKKTKCDGKRPCEACMVSYVRRNKIGSADEVDVKKIKCVYSPAKRRGPPPKRTLEREMEERERERKQRREEEHPIAGLGRVPEEVVSSAANLNNLDTASILNLLSMLNPAASTLPPPMPPPIDPQQSLLSSLGNALAGIQGIGMPQGFGGGATASGGYNTMNNAPSAASQQLAYLQQLQQQLQLQQLQQHLQENLQQQLQQQQQPLTQQGQTIRGAESSMSSSLEDNRTQSLQNEVGRLRKRINELETENAELKQKVDALQEVVERATDEDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YED1</accession>
    <name>A0AAD8YED1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YED1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="entry name" value="GroES chaperonin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="78" mass="8749" checksum="F5567AF1A9627C69" modified="2024-05-29" version="1">MVLVERLQGKPATDSGLFVPRDNLPTLHLCKVISMGPGREEENGRIAPMPNIKKGDVVIAKNLGVLDRKMRRQLMERN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFB6</accession>
    <name>A0AAD8YFB6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aldehyde reductase</fullName>
            <ecNumber evidence="4">1.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_004574</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFB6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF831">
        <property type="entry name" value="NAD-DEPENDENT EPIMERASE_DEHYDRATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042156913" evidence="2">
        <location>
            <begin position="22"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="Thioester reductase (TE)" evidence="3">
        <location>
            <begin position="30"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1745283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="384" mass="41950" checksum="5431E4FF46690A90" modified="2024-05-29" version="1">MPPQLFSISLILLILSCCCSGLAIPSSSIVTGANGFVGRHIVHALLIQQRQCDDVIICLVRDGKVKCEQSYWDAYLSDLKESEQCLVKVLPYDMLDDGSTLRSALQAASTSSPSSKICVYHTASVFGPTEDPVQTANDNVKSAEVVVEAMQQFILPARLVLTSSMAAVRATNQTPLNNKYYTNKDWNTLSTLDPNNWGSCYQYSKAESERRASKLVAKCPNDLEFIALCPSFVFGPPPPLPKQLQSQSSLIKQWLSGASQVQSRLCVDVRDVAKAHIAAGQMDLGDSNDHKRYILSTEARLSSELTGEALKRAVEQHLRKSGSSSNIDTSKITCDTVFDGGAIKIGNKEVECTDILRDELGVTCRSVDETFYDMVVAMLAGESF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YH65</accession>
    <name>A0AAD8YH65_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_003073</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YH65"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd24163">
        <property type="entry name" value="RWDD2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017359">
        <property type="entry name" value="Phi-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059181">
        <property type="entry name" value="RWDD2A-B_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15955">
        <property type="entry name" value="RWD DOMAIN CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15955:SF8">
        <property type="entry name" value="RWD DOMAIN-CONTAINING PROTEIN 2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="113" mass="12712" checksum="4A32C8ED0C883CFD" modified="2024-05-29" version="1">MDITNNDRRKQIVIEANEGNLGGYLKPGYPGVVVIEGDAVACDDFVVWIKGNKSRPGGFGRNWGHHVRGEATAEQRQFPEAFEELEDDMGLLGSLCRESNVEDEFREFILQQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YI55</accession>
    <name>A0AAD8YI55_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YI55"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000093">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="1">
        <location>
            <begin position="88"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="345" mass="39198" checksum="F5429A01134B1A03" modified="2024-05-29" version="1" fragment="single">ENITARYFVYARYLYTSHQASHILILLDSFRPTQFAMRMRMRPKENLSRNTDAVADSLAAMIKRELTTYSCYGYDGYLNLSASDPTMVTAGDRKQLVDWCYSIVDQCKLSRETVASAMEMADRFLDMPSNSANAAQVSDEALRDVCKFQLLIIAALYASIKINEKVVISSDLFAEICSHVYTVKEIEDMELTLLNGLSWRCHAPTANQVGLSILSLLLPYVDIPEVTWGFLMDEMKYLTELAVRDYYFSTQRASTNALAAVFNVISDTSTSTKERKELLGAFLRLIVEYFDFDHPNQIAAATSRLKSLPKKSENLLREDNVDERSLDDSVKTCKVSNRSYSQKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIB5</accession>
    <name>A0AAD8YIB5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Phospholipase A-2-activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_003534</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIB5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010992">
        <property type="term" value="P:ubiquitin recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000250">
        <property type="entry name" value="Phospholipase A-2-activating protein isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.870">
        <property type="entry name" value="PFU (PLAA family ubiquitin binding), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015155">
        <property type="entry name" value="PFU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038122">
        <property type="entry name" value="PFU_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013535">
        <property type="entry name" value="PUL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849">
        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849:SF0">
        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09070">
        <property type="entry name" value="PFU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08324">
        <property type="entry name" value="PUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51394">
        <property type="entry name" value="PFU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51396">
        <property type="entry name" value="PUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="129"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="PFU" evidence="7">
        <location>
            <begin position="433"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="PUL" evidence="8">
        <location>
            <begin position="564"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="54"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1745610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="854" mass="90014" checksum="3D933C253B7F3299" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIC6</accession>
    <name>A0AAD8YIC6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mpv17/PMP22 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_003944</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1746020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIC6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF17">
        <property type="entry name" value="PROTEIN MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1746020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="216" mass="23702" checksum="597168B3F3DAFEDE" modified="2024-05-29" version="1">MPYKAGINELGEPALATEESPLILSKSNAAGLAPLFRDPTGAIPGFQAYSDALDKNPVAVKALTSLVGWLLGDLIAQVFISGGSIDYMRLVTLCSFGFVFHGPSGHYFYYYLDEIIPGTDAVHVCSKVVIDQLAWCPVFMSVFFLYLGLVNGDSFATIGNKIKNDLFNACLGSWKVWPIAHLINFKFIPNKWRIPYINAVQIAFNIFLSLLGNKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIF3</accession>
    <name>A0AAD8YIF3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Serine/threonine-protein kinase</fullName>
            <ecNumber evidence="10">2.7.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_002485</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="10"/>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIF3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345:SF91">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE PLK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="434"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="477"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="17"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="26"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1747141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="978" mass="109828" checksum="9678CC0BEA39DCAF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJU7</accession>
    <name>A0AAD8YJU7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001676</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJU7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039448">
        <property type="entry name" value="Beta_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13229">
        <property type="entry name" value="Beta_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="34"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="398" mass="43849" checksum="72ADD2D2B7969B80" modified="2024-05-29" version="1">METNSSIKFKSNDTPQCDDVSNIQNLNLLEARDKDRLSNLPEDVLFSVLLYIGPKDVDESVKLVNQSLHNATSLSLQLWREFCILTGKCLEKKYTNTNADKSTDTVGPGEENLFRSYYFRNPCVPLDFETIDAALAYCSRTPMKVLEDDSEYDYSATGTVCLMPGAYKERLSSRRSMGRRTSGSDLWGGNTAVVVDGARAQVVMNSCVVQSHSGRGIVVTNQAQIQISESTVCDCAATGFYLGDWGSRAHVTGCNIVRNGFGSRQKLTSDEGRQELDYVLTEWTRAMCWIEDTLIASNCLTGTSVVRNGFLSLSGCDITQNTGNGHPISIEDEHDVGNNRLQGARIRGGVIEGPSHNDYSNSQKYQEKLRCGASFAYDALVRAPMTEEELQTILDAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJY6</accession>
    <name>A0AAD8YJY6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">N-acetylglucosamine-6-sulfatase</fullName>
            <ecNumber evidence="6">3.1.6.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_001356</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.14" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJY6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008449">
        <property type="term" value="F:N-acetylglucosamine-6-sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43108">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43108:SF6">
        <property type="entry name" value="N-SULPHOGLUCOSAMINE SULPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase N-terminal" evidence="5">
        <location>
            <begin position="170"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="135"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="78"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1747393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="621" mass="71433" checksum="20D55D41131748DD" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLJ7</accession>
    <name>A0AAD8YLJ7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoglycerate mutase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001294</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLJ7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47821">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47821:SF2">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041977366" evidence="1">
        <location>
            <begin position="19"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="297" mass="32440" checksum="F9411AEBDF9651B5" modified="2024-05-29" version="1">MKSTVAVFLPVFIATASGFVSSPSTSCAKNHVYKPLFATGVNPQEPSVKVVGAMPDALPPLKNHYYLLRHGQSTANVEGIISSARSLAGSTKHGLTLLGIEQGRDSAPSLIDFIEQDLKDDDTTSTKEVYFYSSPFARAKETAEQCLAGMRANDEVAKRIEELGLKVKKEVMLDDGLMERYFGRLDGTELLTYAYVWPVDMFEPTHTAFDVESVAAVSTRIRSTILDIDSNHDEGGNHIVLTSHADVLQITQVYASGLDNVGKFSQYRFGNGEVRKMGRTVDTLPAPVPLQPPERGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YM20</accession>
    <name>A0AAD8YM20_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Rab family small GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_001030</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Endomembrane system</location>
            <topology evidence="12">Lipid-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SLC35F solute transporter family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YM20"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01868">
        <property type="entry name" value="Rab11_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000067">
        <property type="entry name" value="ras-related protein RABA1f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009262">
        <property type="entry name" value="SLC35_F1/F2/F6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06027">
        <property type="entry name" value="SLC35F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="9 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0636">Prenylation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="253"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="374"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="757"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="763"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="800"/>
            <end position="812"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1749091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="812" mass="90347" checksum="BEC18A2D2B031CC8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YM81</accession>
    <name>A0AAD8YM81_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TWIN LOV 1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_001669</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YM81"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14809">
        <property type="entry name" value="bZIP_AUREO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47429">
        <property type="entry name" value="PROTEIN TWIN LOV 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47429:SF2">
        <property type="entry name" value="PROTEIN TWIN LOV 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0157">Chromophore</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="7">
        <location>
            <begin position="232"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="354"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="404"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="168"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="168"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1747706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="463" mass="49852" checksum="286CDE467650E06D" modified="2024-05-29" version="1">MSPSASCIAIPQYTTAPSNKSTDADCFNTMDSALDFDLLAEYLLEDLGASGGFDFSPENPSVTPPNVTNVQYKLDPGVVTPHQSDPSFFADPLSDPNLLINGDMTNELSQVQQMIANQARAPPAPIQQPTVQPQLPQAPTNPAAVVAAPVMVKTEPIAPAAPTTVQQTLVRPLVPNTSQPNKRPRVDVPGVRGGQPAQQVAKTSFSLASASAAAAAATAAEQAEDASKPKSQAQIDRRRERNRILARRTRLRKKFFFESLQKDVSDLQRENAALKSIVRSRLKPDDAKALLSQCNANEKLPSIANSGEAGDENGAGTADGDGVVKQLDKEDFNLISSIQNSQQCFIITDPSLHDNPIVYASDDFLTLTGYSQDQVLGRNCRFLQGNETSQEKVDLIRKAVKVGEDVSVTFANYTSDGTPFWNNLFIAALRDADDNIVNFIGVIVKVDGPEQGDAEYGKVLSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YN29</accession>
    <name>A0AAD8YN29_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CBS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001011</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YN29"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050511">
        <property type="entry name" value="AMPK_gamma/SDS23_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780">
        <property type="entry name" value="AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780:SF36">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1749072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="260" mass="28311" checksum="5027C43649372187" modified="2024-05-29" version="1">MSNKSAATLLKVVESHDAGDVMNFTIRKKALDRVRKSVSRISVDSSENVERPAVTVIDSKMTPLEASTLLWECNHGRPCCNAESETYIGMFDARDILSCVIAAHKEFEALGGHHHNPGEDTHMVSDVEIHIDDHKTRRDLIAKALQHIKINSKPQSPGAVTVSYLAARNPMTPFMTKDSSLLEVCKVLACRQKHRVPITDSSSGKNSCIGIISQSGLVAFIASKCPPGSLDVKMVDAGLEYKKDVVKISDDASASTPLNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YP18</accession>
    <name>A0AAD8YP18_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000686</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YP18"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33683">
        <property type="entry name" value="1, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33683:SF46">
        <property type="entry name" value="SUSHI DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="433" mass="47591" checksum="B3F6480976EC544B" modified="2024-05-29" version="1">MLCCHELRPAAGAVGFTNDDDINWPGWQMTDEDSTIYEGTIFDYIETVAADLGIGLGDVATTGQSNVGRRELEYRYSSRELKGWHRSIVINNITQRMLPSGSSALDVSLVVTGDYRPPPFLDLDVIAEDSINRQGAKVVSTLRERGERAGREFFSRVEGIEAVAATDLTARPTRSPTGKPTPAPTGPPTAIPSSEPSSAPSSEPSSEPSRSLDQYIMTGSQQDLQLGGKTTSSYGFVFNIRTKPDAGVVLMTGFDFYTETTDDVTFELWTRTGSYVNHKGTFEGWDLIGSGTIKGRGIGRYTAIPPEMFTQVSIPGGGGDKGTRAFYLTLTTINLVYKLGTGGFAPDTKYHHDSPDIEIWEGEGVLFYPFPDPAEAYFYRSPRQYLGAVYYDILPCKPFSTYGPVMELPCPNVPTGSQLCRYRPSHLKRNDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3M6</accession>
    <name>A0AAD9D3M6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Dihydrolipoamide acetyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_016856</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.12" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000066">
        <property type="protein sequence ID" value="KAK1732462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3M6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004742">
        <property type="term" value="F:dihydrolipoyllysine-residue acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:pyruvate decarboxylation to acetyl-CoA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000010">
        <property type="entry name" value="Acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045257">
        <property type="entry name" value="E2/Pdx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151">
        <property type="entry name" value="DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151:SF90">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="4">
        <location>
            <begin position="90"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="4">
        <location>
            <begin position="211"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="45"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1732462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="401" mass="41277" checksum="228E0D9D8684E7E1" modified="2024-05-29" version="1">MISSSTRRLLISSSTRRSASRQRGVVVSCTTSKRCFVSLTQQSQPSSLSWSSNNQTHQEHPQSSLRLDRSSSLTTQQQRWMSSADDLPYHIVVGMPALSPTMTSGSISKWNVSVGDTFIAGDSLAVIETDKATMDFEAQDDGVVAKILVEEGGGEVECGLPIMVTVEEEEEVPAFANFVPDDAAGGAPAVAESAPAPAAAPATPAADLPYHIVVGMPALSPTMEAGTISKWNVAEGESFVAGDSLAVIETDKATMDFEAQDDGVVGKIMVEAGAGEVTVGVPIMVTVEEEEDVAAFKDFVAGSAPDTSATEASVAPVEEVKAPEPVVAAAAPTPAPAAPTPVAAEPAVAAAAPTPVQGAVSLGGSSWGQLAAESSPLARALASKQKEYIEKYGSTGHVPIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3T7</accession>
    <name>A0AAD9D3T7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein MAK16 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_016634</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the MAK16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000061">
        <property type="protein sequence ID" value="KAK1732657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3T7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000470">
        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.110:FF:000001">
        <property type="entry name" value="Protein MAK16 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006958">
        <property type="entry name" value="Mak16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029004">
        <property type="entry name" value="Ribosomal_eL28/Mak16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23405">
        <property type="entry name" value="MAINTENANCE OF KILLER 16 MAK16 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23405:SF4">
        <property type="entry name" value="PROTEIN MAK16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04874">
        <property type="entry name" value="Mak16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01778">
        <property type="entry name" value="Ribosomal_L28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003352">
        <property type="entry name" value="MAK16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal eL28/Mak16" evidence="5">
        <location>
            <begin position="6"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR003352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1732657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="239" mass="28307" checksum="F28B9E839E1563DC" modified="2024-05-29" version="1">MQHDEMIWQVINHQFCSYKSTITKSKGANKDKKQFCKHPYSTTGLCNRSSCPLANSKYATIREENGRMHLYIKTVERAHSPKNLWEKIYLSRNYAKALAQLDEHLQYFPKAQIHRNKQRLTKIHQYLLRMRKLKLRQINGTKSVKARVHRKVEVREERREKKALVAAKIENSIEKELVERLARGTYGDIYNFPEVPYQKALEEVEKQGEEELEVESEEELEVRFVASLCCFVAFMFDCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D462</accession>
    <name>A0AAD9D462_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000066">
        <property type="protein sequence ID" value="KAK1732433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D462"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="662"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="701"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="887"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="208"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="368"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="554"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="918" mass="99898" checksum="E1371BB59BFFAF39" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7Z4</accession>
    <name>A0AAD9D7Z4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_013214</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7Z4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051727">
        <property type="entry name" value="DnaJ_C3_Co-chaperones"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44140">
        <property type="entry name" value="LD25575P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44140:SF2">
        <property type="entry name" value="LD25575P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="J" evidence="5">
        <location>
            <begin position="506"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="92"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="349"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="92"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="116"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="138"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1736078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="571" mass="65412" checksum="758CC9699F3A3D95" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8N3</accession>
    <name>A0AAD9D8N3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UBA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8N3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09212">
        <property type="entry name" value="PUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000003">
        <property type="entry name" value="UV excision repair protein RAD23 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036339">
        <property type="entry name" value="PUB-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143503">
        <property type="entry name" value="PUG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBA" evidence="2">
        <location>
            <begin position="23"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="515" mass="57035" checksum="288A8E443DF7F6EE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8Y5</accession>
    <name>A0AAD9D8Y5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_012498</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1737053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8Y5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013714">
        <property type="entry name" value="Golgi_TVP15"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28128">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28128:SF1">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1737053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="230" mass="26114" checksum="DA74DE6A7F00A8DB" modified="2024-05-29" version="1">MDNPGWANSELAEEEGQPLSNKRPSMFSRVSAPTMPATNNNVMEAETDNNTQPSFQRTFSHKIFRLLKIITTLVAILLLIAQVISLVYLPFDGVELLLKIFLSSFCVMIILNELEWSGILRSSPLLWNWLPRGYIYAFIGLVSVEENNLKPSSGALNTLPIDYTAAVFIETASWMMFVMGILYISLSLCCCQLIQTKVRENYKERVAERKKIFEDGLTSLEFRQNDPTMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D902</accession>
    <name>A0AAD9D902_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glutamine-dependent NAD(+) synthetase</fullName>
            <ecNumber evidence="8">6.3.5.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">NAD(+) synthase [glutamine-hydrolyzing]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_012101</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>deamido-NAD(+) + L-glutamine + ATP + H2O = L-glutamate + AMP + diphosphate + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24384"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">In the C-terminal section; belongs to the NAD synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.1" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D902"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003952">
        <property type="term" value="F:NAD+ synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07570">
        <property type="entry name" value="GAT_Gln-NAD-synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00553">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000036">
        <property type="entry name" value="Glutamine-dependent NAD(+) synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.110.10:FF:000003">
        <property type="entry name" value="Glutamine-dependent NAD(+) synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02090">
        <property type="entry name" value="NadE_glutamine_dep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014445">
        <property type="entry name" value="Gln-dep_NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003694">
        <property type="entry name" value="NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090:SF9">
        <property type="entry name" value="GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090">
        <property type="entry name" value="NH 3 /GLUTAMINE-DEPENDENT NAD + SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006630">
        <property type="entry name" value="NADS_GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 8" id="KW-0520">NAD</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="10">
        <location>
            <begin position="69"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="12"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="13"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00052340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR006630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1737234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="797" mass="87869" checksum="A6FF5F4FFBDACDE8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D964</accession>
    <name>A0AAD9D964_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010197</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D964"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="146" mass="16460" checksum="944CBDDA222E1693" modified="2024-05-29" version="1">MHDQHSTLFRRLRFFAALILLAASVAVNLLLLPKFLSTTIASTTSSDKPPQAQGAATNLDDVRSDGNNDDDDDSIRIIALCGGSLYFDDAFRKMSEWLPILYAGMYQPPEDETIPQKVWCENEIEQWVSSELRRQQISTCPPQQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9F3</accession>
    <name>A0AAD9D9F3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_011487</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1210"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="3">
        <location>
            <begin position="395"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1737715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1358" mass="151537" checksum="5AFBA8328E36CB61" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9Z3</accession>
    <name>A0AAD9D9Z3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9Z3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00136">
        <property type="entry name" value="PDZ_canonical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="432"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="620"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="176"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="273"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="342"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="625"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="644"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="657"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="683" mass="72191" checksum="5A4F99D6DB7F20E9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAD7</accession>
    <name>A0AAD9DAD7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAD7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030132">
        <property type="term" value="C:clathrin coat of coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030130">
        <property type="term" value="C:clathrin coat of trans-Golgi network vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071439">
        <property type="term" value="C:clathrin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032051">
        <property type="term" value="F:clathrin light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006898">
        <property type="term" value="P:receptor-mediated endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.110">
        <property type="entry name" value="Clathrin heavy-chain terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016025">
        <property type="entry name" value="Clathrin_H-chain_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10292:SF1">
        <property type="entry name" value="CLATHRIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10292">
        <property type="entry name" value="CLATHRIN HEAVY CHAIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50989">
        <property type="entry name" value="Clathrin heavy-chain terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="114" mass="12336" checksum="62D7AD61797641D0" modified="2024-05-29" version="1">MAAGVPIAFQEVLNLQQLQVPETSIKHGLTTMESDKWIVSVEPNQVSLIDLQNQAQVTRRPIKAEAAVMNPSSNILALRSGKTIQMFNLDSKSKLKSHDVDSPSSFGSGPPPPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DB30</accession>
    <name>A0AAD9DB30_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Kinetochore protein SPC25</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_008927</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the NDC80 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
            <location evidence="1">Centromere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Chromosome</location>
            <location evidence="9">Centromere</location>
            <location evidence="9">Kinetochore</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SPC25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DB30"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031262">
        <property type="term" value="C:Ndc80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23784">
        <property type="entry name" value="RWD_Spc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.457.50">
        <property type="entry name" value="Chromosome segregation protein Spc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045143">
        <property type="entry name" value="Spc25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013255">
        <property type="entry name" value="Spc25_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14281:SF0">
        <property type="entry name" value="KINETOCHORE PROTEIN SPC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14281">
        <property type="entry name" value="KINETOCHORE PROTEIN SPC25-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08234">
        <property type="entry name" value="Spindle_Spc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="8 9" id="KW-0137">Centromere</keyword>
    <keyword evidence="3 9" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="5 9" id="KW-0498">Mitosis</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromosome segregation protein Spc25 C-terminal" evidence="11">
        <location>
            <begin position="180"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="55"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1740832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="257" mass="29217" checksum="A8ADE53D775C2628" modified="2024-05-29" version="1">MPTTSTMTTATITNYTGFTSTFVDRIATSRRRLDQYVETNKQKADALVAELKTCEANEQSKIDSLLRQLKSLQYERGVAKDANKAAAAGTDGVTGVAEQRKKLEHKQAKLQQEVEMLQSKNRMEQSHLEEVLVKEKKARQQAQEVRAKKMEIEAQRGMTMEDLTKGLLNYKYTGLAFQKGDNGALNFKFTKIDHDHPDKPFTFALILDPDTDLYQLTDCNPRLDQKDIDEVLNVLNADKHGFNGLVVRMRKLFKETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DB68</accession>
    <name>A0AAD9DB68_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008338</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DB68"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="120" mass="12038" checksum="DAEB2ED06A994FFD" modified="2024-05-29" version="1">MGLFSGLTKSDGGEYQNVGSATTSCGGEPPLVTATPISSSTAAAASSSLPTVAEAINISKLAAAGASTSTAAVGAATHNSYSTSSQQQRQSDNGSLGRFPTSIDTCPHCSVQLVMWLHIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCA5</accession>
    <name>A0AAD9DCA5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EGF-like domain-containing protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006851</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCA5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="158"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="244"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="692" mass="78142" checksum="C7C689673CAFF63A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCJ2</accession>
    <name>A0AAD9DCJ2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase</fullName>
            <ecNumber evidence="3">2.5.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007136</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCJ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00299">
        <property type="entry name" value="GST_C_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00570">
        <property type="entry name" value="GST_N_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050983">
        <property type="entry name" value="GST_Omega/HSP26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43968">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43968:SF6">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE OMEGA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13410">
        <property type="entry name" value="GST_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041966533" evidence="1">
        <location>
            <begin position="20"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="20"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="248" mass="28040" checksum="558767466E5D39FE" modified="2024-05-29" version="1">MMATTYIFFFLLSLAVLLPSRPWIALLEKGVEFEHKLIDLSNKPHDFLEKYQDASGRAYGAGLVPLLEHDGNLVIESDVVAKYVSQHIEGVNGRGEDMYPTNNEADEELIKLFVNSWEQVTDTYYSVLTATSEKEVKTHKTSFIQSLGVINNLLKQRNSGAFLLGSTFSYAECISAPWIQRFYVTLPYFRGIDFEEDLLNSFDLLPIWMGEVCDRPSCVESKCPEQEMIAACKRYYVSFVSPGAKGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCT4</accession>
    <name>A0AAD9DCT4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCT4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="122" mass="13827" checksum="BBF2470FA12BEEE0" modified="2024-05-29" version="1">METQSHVVGSLISSLILLTIYMSTALAEGSVAALPWYFFALFLLTPFICLLINEKILKNSDRLIDRRNEMMRRLQLKQTSASGWNQTLTEQPSPCTGMWSPKESQHVNIQQTNMQPDDSPIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DD83</accession>
    <name>A0AAD9DD83_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006634</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1743037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DD83"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="115" mass="12408" checksum="B92226D8BF7FB4C1" modified="2024-05-29" version="1">MWTFPINTSSSSSTTDSPSPPSITIAKEVEPTACETECVDQQKSLVACVESIRAAKLQQAERSSDGSDDDGDTTSTDTPECLPMAVAAWTKCCEEANLRQHEAQKDHEEVVEGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDX4</accession>
    <name>A0AAD9DDX4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_005638</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDX4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF137">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="168"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="3">
        <location>
            <begin position="304"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="653"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="144"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="662"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="687"/>
            <end position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1744041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="702" mass="79360" checksum="DC475C9384AF3797" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDZ7</accession>
    <name>A0AAD9DDZ7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nucleoside deaminase</fullName>
            <ecNumber evidence="4">3.5.4.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_007139</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDZ7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047974">
        <property type="term" value="F:guanosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006152">
        <property type="term" value="P:purine nucleoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01285">
        <property type="entry name" value="nucleoside_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079:SF161">
        <property type="entry name" value="CMP_DCMP-TYPE DEAMINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079">
        <property type="entry name" value="CYTOSINE DEAMINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042103221" evidence="2">
        <location>
            <begin position="18"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="3">
        <location>
            <begin position="106"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1742574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="296" mass="32288" checksum="63D4923AE93AAA91" modified="2024-05-29" version="1">MLLQTIILTVVFATAYAAASNSTSSTMLETIVTTVASIIGAAVVVGLINQQQSISDSSSSSSRQRKSKRDDSSSSDTDISVEGSVMVTLPAWALASWEDYFTRKYTTDEEMMSLAIHLSDRNITEGTGGPFGAAIFERHADNHATLVSIGMNRVVPLGNSTLHGETVAIQLAQRRLGSFTLMLDENKEDGLFYDESHDDDEKESSTPRKRQFELFTSCEPCAMCLGATLWSGVSRIVCAATKDDAQSIGFDEGPVFEQSYEHLEKAGIQVTRNILREDAAKVLQRYGTSGRIYNRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFH7</accession>
    <name>A0AAD9DFH7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ShKT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_004802</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutathione peroxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFH7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000889">
        <property type="entry name" value="Glutathione_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003582">
        <property type="entry name" value="ShKT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592:SF78">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00255">
        <property type="entry name" value="GSHPx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01549">
        <property type="entry name" value="ShK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51355">
        <property type="entry name" value="GLUTATHIONE_PEROXID_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51670">
        <property type="entry name" value="SHKT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042249249" description="ShKT domain-containing protein" evidence="4">
        <location>
            <begin position="26"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="ShKT" evidence="5">
        <location>
            <begin position="25"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1744269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="231" mass="26277" checksum="FDF971E02743C4C0" modified="2024-05-29" version="1">MMMINRLCSTVVAIICCLLASRVAASPSDKFPECEEWASRGDCKPNGRPYFMQQNCPLACHKATYRPPETSTNHDIDDFYQLSATDANGKVVSMENFEGYVTVIVNVARLCDYTELFYNTLEHMQGIYPWAVQIIAFPFDSPDASIDACIKQIEADEKDEQHKIRIMKPMDGPDSHPVFDFLKEAFNVEALDSGFASYFFINPDGNFIEMHYGASYNALKRFVDYHVKEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGR8</accession>
    <name>A0AAD9DGR8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002520</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGR8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="327" mass="37232" checksum="78920ACBC8E38D69" modified="2024-05-29" version="1">MEKLITEKYWKHPIFVEALQLERCCEKLEIDMSQMLLPLANLAREIMDEWKGRLRALAVVRDGDSGKKLLQPCLHWNQLPGWRELLRRLKSILCRKPGHGESTGIRPFLLDLQGVPRNNKDAVDKSIEVYLYPPLKNSNNPYAHLEEFVGDVQVLQKVLNIPGMPVLAEERLSGSKSDKATMLDLVTKFNEVWDEEMFVAQYKDWYDLVKRQQELNVGTVSEDGEQQPSLSELAEAIRETEIELSIAMASKDQLDMVRKRLEDLRSSKAKRHAVLASIVQDVGMRELDEIIIVSPPEENATAEFPKLSELGLFGDQLTMSGEVLPLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGT4</accession>
    <name>A0AAD9DGT4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2Fe-2S ferredoxin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004384</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGT4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="2">
        <location>
            <begin position="61"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="202" mass="22093" checksum="FB6B5172020FD05C" modified="2024-05-29" version="1">MSTEEKQKTGKKEGYVPKWKKKATLAEITGTAELSPEEKGLVGAVPITFQQGTGEDATLIKTSAMPGQPLKLVASQAGQYIKYGCGKGECGTCDSLCNGKYLRPCVDVVPTDLTPDPETGEYANLVIQVKGTKAKVVSSGKFFSVKSFFMGFWNNLLGMGGFVRDRRKAKKNYQERISQEEEILRRTAEKKRKKAAEAAGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DH04</accession>
    <name>A0AAD9DH04_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PUB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001424</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DH04"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09212">
        <property type="entry name" value="PUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036339">
        <property type="entry name" value="PUB-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018997">
        <property type="entry name" value="PUB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09409">
        <property type="entry name" value="PUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143503">
        <property type="entry name" value="PUG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PUB" evidence="2">
        <location>
            <begin position="99"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="220" mass="24256" checksum="3A747F6633410C4D" modified="2024-05-29" version="1">MFGNDRTKDLGENSNDECCMCGEEWHEGKKGWVLCDTTECENTVCQNCTTLLSLSVSELFYCPLCAGSGNSAAATAGATFVSAVKACSELEKLPLSFKATQKILSNLLKSPEDPKYRKLRITENKKVKELLDFAPVLNILASIGFARKHCPRESKSENETGSTMPTEEVLILEGEVPTSQIRDFVYILEGLTPQTPTDQVSECKRKADDETADDAKKQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DH58</accession>
    <name>A0AAD9DH58_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_003604</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DH58"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288">
        <property type="entry name" value="4-NITROPHENYLPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288:SF90">
        <property type="entry name" value="OS08G0542600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13242">
        <property type="entry name" value="Hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1745680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="158" mass="17505" checksum="14784D4261CBDB18" modified="2024-05-29" version="1">MEYWRVMEQSMMVAAEKKLPMLVSNPDKVRPDEGLPPMPGAIGDTYERFVWTTHCAPVGDMTEEKARIGKPFQEVFDIALQDSDPSRAIMIGDALETDVTGATNAGVGSLWVVQDGIHAEDVTKTSAEGVIAGFNGNEFTYAYGKKVMPNYVTEHFRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHB1</accession>
    <name>A0AAD9DHB1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Patched family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_002506</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the patched family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHB1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1640.10">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053958">
        <property type="entry name" value="HMGCR/SNAP/NPC1-like_SSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051697">
        <property type="entry name" value="Patched_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10796">
        <property type="entry name" value="PATCHED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10796:SF92">
        <property type="entry name" value="PATCHED-RELATED, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12349">
        <property type="entry name" value="Sterol-sensing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82866">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="290"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="315"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="392"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="417"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="483"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="714"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="805"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="838"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="4">
        <location>
            <begin position="310"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="19"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="875"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="43"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="875"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="902"/>
            <end position="913"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1747162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="913" mass="98791" checksum="245E4A5784EC47CA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHH5</accession>
    <name>A0AAD9DHH5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHH5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="405" mass="45984" checksum="08F7C45ABAB7EF94" modified="2024-05-29" version="1">MKAGKMALDGCDHKTAYSYLGVALSLLPNDHWSSHYDLSLRLYFLKSSAANSICQYYEAELFLRMTLEKARCLDDQLPSYLLLSQILQAQGNVNDVYDSCSTVLTELGESIPVTYTLSESSEMLEETLKMYEEVGDKWLKGEKTVDKTLQTTLQFYNVIVLASYFCKSYSMVAYFTCKAMQLSLQRGLCDHTPLALIQFTTVLNKDENAMLCYRIAKDAMSLRERFDVAAQIPELYFNFYGRIAWRFEPFQAGIDKLRQGFEAGLSSGHADMGLHCAIQVIKTTILSGANLSSILKEIDYYLHLLKTKSEVTRNFLRVFRKTVSLLIDNGEATSTAADPCIGVGDLNDQNRKLRDAVLQHSVIRCYWSGHNERCRNFGEKCKHLFGQGRQSTSYIAQFFFGKLQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHJ9</accession>
    <name>A0AAD9DHJ9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">2OG-Fe(II) oxygenase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_002024</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1748061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHJ9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24014">
        <property type="entry name" value="2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24014:SF4">
        <property type="entry name" value="2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0847">Vitamin C</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042184064" evidence="8">
        <location>
            <begin position="21"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="9">
        <location>
            <begin position="326"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="24"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="30"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1748061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="459" mass="51866" checksum="2606F57EB57228BE" modified="2024-05-29" version="1">MRFCGLLLSVLLIILSKSESRRSRGVTYPSSMHRSNNMDSSNNSSEQLGGGAINEKQRTLGNSANSVHEKEESWDPSNKLSHILHSIVGLDRYPNYLSRYDESDIAAIEHALEQTLNDVRQQRKQVLQRRNGIRELVEKYNNALANPSAIYDDSQASSDSNDVLQISSLLQPKSWSQLKDVLSDEAFEIIYASIISLSKSTQQTLPSVEDVIRGKFAVQLDPALLEDWMSQECFDVYSFQLLSKDFCSRLRHTITDLSKLGESSEFCSLLLGRRPIDFDTVGLNWISDMLLHMFILPISRHLFATTEKLLSSEDASNDNNNNTKDFLNWRQGYVAGYSANPQSDRAVTRHRLVPHSDDSEVTLNCCLGEEDFEGDNVQFYGLRGTPNEGKLLGEVERPDVGRAVIHAGRHLHAVSEVTAGNRYALIVWTRSWGMRRLTCPCCHLNRRMDASCICDSRWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHR2</accession>
    <name>A0AAD9DHR2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_000195</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHR2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="235"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1748256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="295" mass="34310" checksum="8A68E669B4778DF8" modified="2024-05-29" version="1">MDRLLLTDELTGEDVRIVDWDFRNINASDFKKNFKEMIQNPLKRLLNDFNRDPHVQMPETLKESMLGLIRDLINYYYYMASQPSNQKQWNLLEMVGNQTNPKVAWIHFPSVTKAFKTCLSIIDAKNRPSMPFVFMIRSVGEVRDVFSKDASFLSQMMRVHGGARPGYFPLVISWKLQELVPTTLPDTFMETKVVSLFSEEEIKGTTFTPDVSKESFLLESLLADKSLQVYTDGDCAFCKKSGVHRLDRCSRCRVARYCGRVCQTEHWKIEHKHHCKRLLQLRLEANRKAEEEEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DI96</accession>
    <name>A0AAD9DI96_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DI96"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="17"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="75"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="202" mass="23678" checksum="1EFE7B1FB2B247FA" modified="2024-05-29" version="1">MDMIRKKKMREIASMQAARLKKQQQQLDEINDDKIKDKERARKESRDKASAQVNKGMEHLDKLESDRTNLEGIVLAGWKEKIVEFEQHMSELQKKELDALKLEHEGVIEKMMNDIREENNADRLKLTEALNEVGNEKKRKLDDSEDGTAEEKEMQSVVKQKELKTIMEEMNDLNKTKGQMVWLLKQVITAELMKKKKKSKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DII0</accession>
    <name>A0AAD9DII0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DII0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051057">
        <property type="entry name" value="PI-PLC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593:SF113">
        <property type="entry name" value="SI:DKEY-266F7.9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="347" mass="38727" checksum="59C96C63E75C1D4A" modified="2024-05-29" version="1">MNYNNYYDGQDQGSTWNKVSTGLLALYGKTQVGSVYQQLNDGARALDLRPKIYNNGTIGFHHGSLINIPLTSITLGGLLDDAKQWCNDNPKELVILFHHELTHEAGYNALSSEVYTEIDDFYVADDDGVSTNDDEESSNDNGYNDDEQKSSYSYYYSGIAKLKQVYRDHGIPYYPCDMLSGVTVGEAMGLADLSKLGGKGYLLAVDRHDMYASFCGKANWASDELVTCHSKNEERDETSQYQMCTDRKNTGMNKLSALQEYVLASANNDATDNAYELGPPADESYYPFNQIQGFWQVDSTSVTIGVTHAASTLLDDNRRSNVNAEMVQLAYDRNSRRSTYLPWTTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJ19</accession>
    <name>A0AAD9DJ19_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 4C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_001306</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the eIF-1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJ19"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05793">
        <property type="entry name" value="S1_IF1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00216">
        <property type="entry name" value="aIF_1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001253">
        <property type="entry name" value="TIF_eIF-1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018104">
        <property type="entry name" value="TIF_eIF-1A_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00523">
        <property type="entry name" value="eIF-1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21668">
        <property type="entry name" value="EIF-1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00652">
        <property type="entry name" value="eIF1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01262">
        <property type="entry name" value="IF1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50832">
        <property type="entry name" value="S1_IF1_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1-like" evidence="9">
        <location>
            <begin position="22"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1747343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="140" mass="15766" checksum="24AAE65628B5E412" modified="2024-05-29" version="1">MPKPKGKGGKNRRRGKGDGEEAKRELEFKEEGQEYAQVVRMLGNGRCECFCYDGVTRLGHIRGKMRKKVWVTAGDIVLVGKRDFQDEKVDILHKYSADEARNLKQYGELPETARINETAVDQAMAGDGDDDDIGIDFDDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJ85</accession>
    <name>A0AAD9DJ85_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_001486</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJ85"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511">
        <property type="entry name" value="SYNAPTIC VESICLE GLYCOPROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511:SF34">
        <property type="entry name" value="SYNAPTIC VESICLE GLYCOPROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="85"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1747523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="310" mass="33349" checksum="94C8790513F41E87" modified="2024-05-29" version="1" fragment="single">FFKNPAAGPSTRSGSPKPISTVLFALEQKRQQTSSLHISSMMSESQPLNATQRLPPPGSPRSIDDVLEHAYSSTTIKNLWRFYIIFFALGLANSGDSAEMGCMGSVMASSQFQHDILQGSLYSEADFAKRGAAIAGAHMAGMLISGLLAGVLADVWGRRKTLLLGLACNSFVGIASAMTRTATQLFILRFVCGLGLGLVISGVVTLSAEIAPPSKRGRFMAIVGSCYTLGYLYISFWAVTIFQSSGSGNWRVFMVVNAIPTLLSLSIAYAHVPESPRFYLSRGMLKEAAHATNSIASKLGYVDHYLTERN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DL00</accession>
    <name>A0AAD9DL00_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001172</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DL00"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1749233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="282" mass="31229" checksum="1EF65075A996936B" modified="2024-05-29" version="1">MTKPTEEAVIFKSHKQEKAKQAATSRSSQHEPIKEVKEQDDVKGRVRSINRIFSRISIVPSAKSGLPAQVSVDTKRHLTLTPRPRTANSLVSKVFSPESANGVVITSTRTMEDKNFDQSTTVFRLQSEEGVVITSTRKVDELREDAFAKSNSTLMTVSSHEDSNYCGAKNRSQLQNDALLLASAKQAVGPARAKDKDYARNTSTPNTFIVADDKKTSGTNKESDLIDEEDREASIFRRIGGAVDACSMRLCFERDEEQFIVIVPEGYFVDDDVSSLSGLSRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2LBW7</accession>
    <name>A0A7S2LBW7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NTF2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_012701</name>
        <name evidence="3" type="ORF">SMAR0320_LOCUS10561</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="HBGZ01014785">
        <property type="protein sequence ID" value="CAD9601681.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S2LBW7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002075">
        <property type="entry name" value="NTF2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02136">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTF2" evidence="2">
        <location>
            <begin position="286"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="428"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="244"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="440"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CAD9601681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1736679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="450" mass="47956" checksum="89B7D07C160DE44A" modified="2021-06-02" version="1">MEDRHSVSNPRPFPGGGSDGVKVIPTWEVDIIRDGSVIVDTFVLNNEVLPPRKNKKGKVLWCLPKDLNKTPSFGVHENSRILDIFKDRKKKRKKQLKESGGKASESPKKRESLADSGEEGGGKLDRRDSKGNGNAKSKKSGKENGKSDENNVSVTAKEKDVRAGKHPQLQAARMRLGGIGQRQNKKQHQSDILDGDPISPSSMQMEASGSLITLETEAPDTVDLSRLSLDDAAPTKQQSPNETSRPAAKAPSSAAPSPDALFIVIPRNELPNPLPGERELSLAVPAARHFVNTYYQHFSAAQINDLGRYYTAKGQKSVSIGGAHSVVTGRNDIATQILSLAGTVFSVRGVVSQDTVDGQGAHILVTGSAVTGSGGVSANFAHSVSLTRVKPELQVESTCPALTAAFEAGIPFQIHNDALALLSGEAAPMNQPQFTSPAPAHHPPPPPGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2M6T5</accession>
    <name>A0A7S2M6T5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Programmed cell death protein 5-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_015516</name>
        <name evidence="3" type="ORF">SMAR0320_LOCUS20961</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PDCD5 family.</text>
    </comment>
    <dbReference type="EMBL" id="HBGZ01029474">
        <property type="protein sequence ID" value="CAD9626768.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000044">
        <property type="protein sequence ID" value="KAK1733819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S2M6T5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.140">
        <property type="entry name" value="PDCD5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002836">
        <property type="entry name" value="PDCD5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036883">
        <property type="entry name" value="PDCD5-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10840">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10840:SF0">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01984">
        <property type="entry name" value="dsDNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46950">
        <property type="entry name" value="Double-stranded DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="116"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CAD9626768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1733819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="147" mass="15538" checksum="04E92EF6314AB1EE" modified="2021-06-02" version="1">MSGMLPNNISSSGVSASEIPDGFSLAGPNSGGGGGGGPSDSAAEQAKQRQAQREAILEQAMTPDALARLRRVKLVKKDRASAVEGMIANMAMQGKLDSKISEGKLIEMLEGIVGAQQKKEGDKGKISIQRKRYNFDSDDDDDDDDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1GXK6</accession>
    <name>A0A8K1GXK6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Large ribosomal subunit protein bL36c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rpl36</name>
        <name evidence="6" type="ORF">QTG54_017152</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="7"/>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2021" name="Front. Plant Sci." volume="0" first="0" last="0">
            <title>Chloroplast Genomes for Five Skeletonema Species: Comparative and Phylogenetic Analysis.</title>
            <authorList>
                <person name="Liu S."/>
                <person name="Xu Q."/>
                <person name="Liu K."/>
                <person name="Zhao Y."/>
                <person name="Chen N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CNS00100</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Plastid</location>
            <location evidence="5">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL36 family.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MW679506">
        <property type="protein sequence ID" value="UAM91360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_010200865.1">
        <property type="nucleotide sequence ID" value="NC_058701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1GXK6"/>
    <dbReference type="GeneID" id="68637984"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00251">
        <property type="entry name" value="Ribosomal_bL36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000473">
        <property type="entry name" value="Ribosomal_bL36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035977">
        <property type="entry name" value="Ribosomal_bL36_sp"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01022">
        <property type="entry name" value="rpmJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42888">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L36, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42888:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL36C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00444">
        <property type="entry name" value="Ribosomal_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57840">
        <property type="entry name" value="Ribosomal protein L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00828">
        <property type="entry name" value="RIBOSOMAL_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 7" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1732109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UAM91360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="37" mass="4390" checksum="E66B87479C4AEDE3" modified="2022-08-03" version="1">MKVRPSVKKMCDKCRVIKRHGKIMVICQNPKHKQRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XS01</accession>
    <name>A0AAD8XS01_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DnaJ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_016562</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000058">
        <property type="protein sequence ID" value="KAK1732759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XS01"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45188:SF2">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45188">
        <property type="entry name" value="DNAJ PROTEIN P58IPK HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13176">
        <property type="entry name" value="TPR_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042295645" evidence="4">
        <location>
            <begin position="38"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="56"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="244"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="361"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="5">
        <location>
            <begin position="417"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1732759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="524" mass="59847" checksum="C0E8FDE83A008D72" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSH8</accession>
    <name>A0AAD8XSH8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WRKY19-like zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016642</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000061">
        <property type="protein sequence ID" value="KAK1732665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSH8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056866">
        <property type="entry name" value="Znf_WRKY19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24906">
        <property type="entry name" value="Zf_WRKY19"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="395" mass="42839" checksum="86B297BBBB007B70" modified="2024-05-29" version="1">MKSDPSYTKGTIAIASTTTRRPTDTDSTNSISRGSGGNNTTNTGSLPAHYLLSPWYHYQLTTNSLPNHYLLTTTTYHHRGNTINTLRPGHYSLFRPGFACLCAAQSKPPCLCAAQSKPPTDLAISNHLASPFDTIHPFCSTALLPPPPPFSVPKSKARQVTMSTKQRAEAATATKVVEEDDIGALIYRESQLRKREAAAAKKNERNSSASKHRATSTHKDSAAAIRGDSSFATPESRQLIEKRKRHLPTDVDEGKEPAKKVARKKKYRYECSADGCTNNVVKGGVCWRHGAKDKAKVKQCSFIGCINIVQQGGVCIKHGATVKRCSKEGCTNAVKQGGVCIKHGAKVKRCSSEGCPNKAFIGGVCIRHGAKSKRCSSDGCTNQAQRRGLCKRHCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSN6</accession>
    <name>A0AAD8XSN6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016323</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000055">
        <property type="protein sequence ID" value="KAK1732992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="743"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="914"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="993"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1370"/>
            <end position="1405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1418"/>
            <end position="1476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1498"/>
            <end position="1525"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="546"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="38"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="86"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="217"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="296"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="753"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="800"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="827"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="856"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="928"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="947"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1002"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1370"/>
            <end position="1389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1390"/>
            <end position="1402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1420"/>
            <end position="1438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1450"/>
            <end position="1476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1498"/>
            <end position="1515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1569" mass="178098" checksum="26006CEEF5C2EF8D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTL7</accession>
    <name>A0AAD8XTL7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000053">
        <property type="protein sequence ID" value="KAK1733180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTL7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013584">
        <property type="entry name" value="RAP"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51286">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RAP" evidence="1">
        <location>
            <begin position="53"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="111" mass="12623" checksum="C9444BB0FA50D0F7" modified="2024-05-29" version="1">MLQRFHLQEPTLSKRQDDVVAQLSYIGLDPKEEVIMESGYRIDALVEVNGKQVCIEVDGLSHLIGKNRSPLGITILKRRQVPSIDGIELVSVPHWDWQKIVNDKKKKQGAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XU02</accession>
    <name>A0AAD8XU02_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015552</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000045">
        <property type="protein sequence ID" value="KAK1733697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XU02"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="279" mass="31674" checksum="203ED5334B2AEB05" modified="2024-05-29" version="1">MGVQEHAFVHSNFILIALTNHVIRLCTDFGCYYHECFLRGHPRLTVLMRRASSGQGKVTPNMHSEPDFYLIAQQYSLETPADVPDRDDKRVVSKVAKASVSGRQKSQCPGDSDVGDEASGYKEDDDPLMTRKAAEPGMDGMSNQHQWDPFDQEIDSAHLHHQEAAPRAGINQFFSMRSQSHSFASGGAKESESNAQAAMNYDPFPYQQQSGSGSYRDRGYSDPSPMPNHRWVHKEDKDWLKLKVTLKRQQVLILQHNRTPQLKEIVIETLLILFRFSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUW1</accession>
    <name>A0AAD8XUW1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="578"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="372"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="423"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="474"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="496"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="547"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="611"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="626"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="685"/>
            <end position="694"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1419" mass="161324" checksum="CFB65526BCAF8F2E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV82</accession>
    <name>A0AAD8XV82_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000040">
        <property type="protein sequence ID" value="KAK1734224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV82"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="323" mass="36695" checksum="86A512D17633DEA9" modified="2024-05-29" version="1">MANKAVVGAQDGNEIFVYMGGDQVVPRNVIRVRIDKSVKIIPQSAFYNRRRLIYVEFHDGIEIVEKHAFNCCTSLRGSIKLLGVKIIGNGAFYNCRDLTDVEFGDKLETIGRSAFSTCNSLRSVTMPSIRIIEEFAFMLCDKLTDLEFGEELETIEESAFKCCDRLRRIAMPLKDDMIGDRVFSFCPNLATVHLVGGFHRTVASLHLESWKNEMNEEINRVNQVLPGTHEQEKTPVVQDWMRSVIHRIDHFKAEHKALLKEATTLLELALWKANLDDNEGGVLEKEGARTTRGRRKRARKEICVTSGASIVIKNVLPFFTLFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVF5</accession>
    <name>A0AAD8XVF5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">RNA methyltransferase, RsmB/NOP family</fullName>
            <ecNumber evidence="9">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_014939</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVF5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001510">
        <property type="term" value="P:RNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054728">
        <property type="entry name" value="RsmB-like_ferredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018314">
        <property type="entry name" value="RsmB/NOL1/NOP2-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807:SF53">
        <property type="entry name" value="RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22458">
        <property type="entry name" value="RsmF-B_ferredox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01153">
        <property type="entry name" value="NOL1_NOP2_SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6 9" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042297508" evidence="7">
        <location>
            <begin position="24"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="8">
        <location>
            <begin position="144"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="371"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1734432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="436" mass="48656" checksum="4041C46AE93F1B64" modified="2024-05-29" version="1">MHITSILTSVALLLALPTKTAVSFSPGVANRAIHILEEASSQNIPVDAALRRYAKYQERSYVKSEEYKSISDILRNISISQYRIDWQLREAGVECSPENRVAFLKKGDPLECRGMDLQTTLECPDWAWTGLKEAFPDEEDLSKELRALMQPAPLDLRVNTLKCEERIDALREIINAGYDATSTPWSPIGIRLEERTALGRIPGLLDGIVEPQDEGSQLVASLLEAQPGETVADYCAGSGGKTLQIAASMKNKGRLYSMDVSEDRLERGKPRCKKAGVSNVQRQVVQEDMTRKDKWLKRRKGTFDRVLVDAPCSGVGSWRRKPDARRTWATFDDGFDGGIDRLANLLPLQQQILQRASRLVKVGGRLVYVTCSLLPQENEKQIIQFLESDVGAEWKVESPPSDFAIPFEVVDGQFLRLTPAQHNTDGFFAAVLTKHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVS1</accession>
    <name>A0AAD8XVS1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014742</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000038">
        <property type="protein sequence ID" value="KAK1734494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVS1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="106" mass="12128" checksum="7A0FD02A1CD965C0" modified="2024-05-29" version="1" fragment="single">HFHPFSPFNLLPIALSYFSVESRASPNKNLKSKKDGTHRRPRNRHDLHNQRSHRRHPRHLRQGMVQITHSSTTHYCIFVGDWRAGSLFAVGDCSVEEGVGDADESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWA5</accession>
    <name>A0AAD8XWA5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rubredoxin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_014563</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWA5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024934">
        <property type="entry name" value="Rubredoxin-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48136">
        <property type="entry name" value="RUBREDOXIN-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48136:SF1">
        <property type="entry name" value="RUBREDOXIN-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57802">
        <property type="entry name" value="Rubredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50903">
        <property type="entry name" value="RUBREDOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042123996" description="Rubredoxin-like domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Rubredoxin-like" evidence="3">
        <location>
            <begin position="65"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1734690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="147" mass="15846" checksum="4992EF5F6A2C22D5" modified="2024-05-29" version="1">MKSIIAIISAICLLASSAFAFAPATPRTLVAPRSAVAPTSLNVFGKRKTEAQKAEEAERAAQFWQGEWVCKDCGYIYNRGECAGMYFEEQGAGFRCPQCSGPRRRYAKKVGDRIGTTLDGGDAPILLFSFGGLIATIAFGVWAVQNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWB7</accession>
    <name>A0AAD8XWB7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD-dependent oxidoreductase</fullName>
            <ecNumber evidence="8">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_014769</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000038">
        <property type="protein sequence ID" value="KAK1734521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWB7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041957635" evidence="6">
        <location>
            <begin position="26"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="7">
        <location>
            <begin position="139"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1734521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="437" mass="47813" checksum="32A10606E798ABDA" modified="2024-05-29" version="1" fragment="single">SFSDAAHFLLLTVLGIAGNPSTADAASASPVSGWRSDLDWAALTSKLSSSASLIDTSLDDYTDECMPEFSEPSPTTHALIDQPSGMCLPHLLLGWEMSWPRPSENHHMDQPYVQAYFDLFGLDPTADFESWMSDPTNPSLNLPYKVLFPVVASDVVAAVNFAKENRLEISVKNSGHSYQGASSKKDTLLLNMNRYTHYAPTGITDCDASTLDTTVAEDMSDQPCLLSLAKNKSSTIRVGGGENFDKAYRAVVAANEGGGYKYHLVGGAAGTVSPMGWSFQGGLPGTMAGRLYGLGVDQFVQIEMVLPNGVHVKFGPTEWEDASAEGFIVPKTKVVTGVCRSNPDEHDEEKWIWERCPEDFDIDFNDLWFAVRGGGGGTWGVITSVLLQLHDYLPYTPYLFNRPPTDECSPITTQFSEFKFQYMNTPSLLNVTKEHSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWR4</accession>
    <name>A0AAD8XWR4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_014164</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWR4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041984537" evidence="3">
        <location>
            <begin position="19"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1735098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="379" mass="41028" checksum="40D5BF2822644F81" modified="2024-05-29" version="1">MKLVSTILLASVLGMAMAADSANLRVGDESRQLADADYSSSSSSSSSTSLSGGTWMWYLMLNGLALGVDVTGHGCNGGCQMPSCGKDHRKLNWWGGDDWTGDEWTDDAWEGDSYEGGGGGGGGDGSSDGGGNGGGGNEEHHCPARCCAPHVPAVHIPHKTSAKNTHHSSSSSSSTNTDDKVIHWGDDGHWANDGHSVWSDDGNYWYDDGAWYDDNWGGDGGADGGWDDDGHWANDGYYYWDDDAHNSEAHWLSNNNSEKQSWKSKIFYPLLVVGLVVVALAVALVTRRNKRRREEEEYYASQQAGYVAPPPEKKKKWYQKFRRNKKKSEASAAAPVQEASYDNSMGGDFSQMQDEDDRSTGNGSTGGWSARSFGTRSYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWW7</accession>
    <name>A0AAD8XWW7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_014071</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWW7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050502">
        <property type="entry name" value="Euk_RNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025">
        <property type="entry name" value="OS02G0815200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025:SF1">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="150"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="100"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1735005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="271" mass="30179" checksum="B4D5A20F2AAD8C30" modified="2024-05-29" version="1">MGNSNSMKQQLCDMNDTTAYQYEDAAAANFPRADSPPATFASTSTLISWAYQSTLPPVVVPHQHGRAPSPTSVASTSTSMAMMQQPAFVWATYSEPHPHYAPSTEAAPEPYSYTPKAHQFQPPSPPDADSDDHDYDIPLLEYSVKSRRGKELFVAHIPFDMTEAELLALCSQYGDVISASIMRHDLGVSKCFAYVKFKLQSTADNALLRLNRYEVDGKFLFVDYAYAMRLAQERSLSVMMMENIKPIASWSVELHLLLSREPSGKVELFSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXD1</accession>
    <name>A0AAD8XXD1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein archease-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_013772</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the archease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXD1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072669">
        <property type="term" value="C:tRNA-splicing ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006388">
        <property type="term" value="P:tRNA splicing, via endonucleolytic cleavage and ligation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.55.10.10:FF:000002">
        <property type="entry name" value="Archease, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.10.10">
        <property type="entry name" value="Archease domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002804">
        <property type="entry name" value="Archease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023572">
        <property type="entry name" value="Archease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036820">
        <property type="entry name" value="Archease_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12682">
        <property type="entry name" value="ARCHEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12682:SF11">
        <property type="entry name" value="PROTEIN ARCHEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01951">
        <property type="entry name" value="Archease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69819">
        <property type="entry name" value="MTH1598-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Archease" evidence="7">
        <location>
            <begin position="48"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00071898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1735609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="190" mass="21284" checksum="820E117DDE1D3109" modified="2024-05-29" version="1">MEPSSDKQQQRQITDEATPTQTTTNATTKINKQIQQSNPGVPPQGAQFEYLNHPADIILHSWGTDLPSSLCNIALCMFGYITSLESISTNEAESNEHGSHMVAEGHDMRSLVYSFLDEWLYNFHAFDFVANAITIEEINLDKWTVVSSGKGEVMDISRHPQGMEVKAITYSGMRIDEKEGRVDIYVVVDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XY85</accession>
    <name>A0AAD8XY85_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphatase 2A (PP2A) regulatory subunit-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_013225</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XY85"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000318">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A regulatory subunit A gamma isoform"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000357">
        <property type="entry name" value="HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051023">
        <property type="entry name" value="PP2A_Regulatory_Subunit_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648:SF4">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2 (FORMERLY 2A), REGULATORY SUBUNIT A, BETA ISOFORM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02985">
        <property type="entry name" value="HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="HEAT" evidence="2">
        <location>
            <begin position="368"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1736089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="680" mass="73712" checksum="3E00F6E80AA1ED0F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYH2</accession>
    <name>A0AAD8XYH2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UvrD-like helicase ATP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_013511</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039904">
        <property type="entry name" value="TRANK1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21529">
        <property type="entry name" value="MAMMARY TURMOR VIRUS RECEPTOR HOMOLOG 1, 2 MTVR1, 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21529:SF4">
        <property type="entry name" value="TPR AND ANKYRIN REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="7">
        <location>
            <begin position="645"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="283"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="341"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="554"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="37"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="286"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="666"/>
            <end position="673"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1735805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1488" mass="169823" checksum="2A9E1D9605044281" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYQ6</accession>
    <name>A0AAD8XYQ6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peroxisome biogenesis factor 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013323</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYQ6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045046">
        <property type="term" value="P:protein import into peroxisome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006966">
        <property type="entry name" value="Peroxin-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28080">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28080:SF1">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04882">
        <property type="entry name" value="Peroxin-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="534" mass="60137" checksum="406E0EDDC10772B8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y121</accession>
    <name>A0AAD8Y121_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_012507</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1737062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y121"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051022">
        <property type="entry name" value="Notch_Cell-Fate_Det"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24049">
        <property type="entry name" value="CRUMBS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="6">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="330"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="375"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="375"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="407"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS01186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1737062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="427" mass="47272" checksum="25747F325C4FDC80" modified="2024-05-29" version="1">MIFYIPQKSKKLCGDTFACKNGSVCKAGEGNEIDHRHKHLDLLSSITSDADGSNYYCECPSGFIGHDCSVEVKECTSHREDLVHSCYFGSECIEADNEYGLLDKFCDCSRAHTEGGFVAGLMCQYTSTTICVDDDKAFASTNDAFCTNGGTCQRIVGSDEDFPGCQCEEGKWDGKHCEYANGVLKDDALDLFSFRKTEILFEENLHGLGGSDAGAESENFSFTSFGVGFGVVVGVGISLLMMLVVRRVRNDKRQLLHEDDYKCFSYDGQAPPPMFSSSRKKEAEVGDDDESTMVFGTEHDVKNEDNVEMLDEATSRILESQFRMTDVRGGAHSVQEDLGGQSEDFTSPYYDDKDEALDRRDFRRISINSGRFPLSSEQHTVSSVMSLDGGDDMDDYEHSNIMSLDGSDSEDDDDDASASNYRIINYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3X7</accession>
    <name>A0AAD8Y3X7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Voltage-gated potassium channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_010338</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3X7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042391">
        <property type="term" value="P:regulation of membrane potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003938">
        <property type="entry name" value="K_chnl_volt-dep_EAG/ELK/ERG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050818">
        <property type="entry name" value="KCNH_animal-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10217:SF435">
        <property type="entry name" value="POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN EAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10217">
        <property type="entry name" value="VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01463">
        <property type="entry name" value="EAGCHANLFMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="36"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="295"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="538"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="569"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="613"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="691"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="752"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="784"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="6">
        <location>
            <begin position="38"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="6">
        <location>
            <begin position="534"/>
            <end position="802"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1739022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1049" mass="120401" checksum="9AF7400EB67B6AAB" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4P9</accession>
    <name>A0AAD8Y4P9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SDR family NAD(P)-dependent oxidoreductase</fullName>
            <ecNumber evidence="2">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009388</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4P9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020">
        <property type="entry name" value="FLAVIN REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020:SF11">
        <property type="entry name" value="OS06G0360300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="1">
        <location>
            <begin position="11"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="256" mass="28464" checksum="A4944043B94EAC7C" modified="2024-05-29" version="1">MAAITTTLVVGATGATGKHVVLQLLQRKQHVKAVVRSKQRLLDSLDEVAPNASTEFSSSLEIQEASLLDLSDDDLMELTSQCDATVSCLGHNISIQGMFGHPRRLVTDATKRLYNAIEANQSKEAEPKKAKFILIGTVAVPNPNGEDDKRTFGERFVQFLLRYMLPPHRDNETAAAYIQGKTDNPNLEWTVVRPTELTDGSASKYEMFSKPIDSLFGGDRSVTRANVAQSMVDMLLTKSLWDEWKFKMPTVYDDLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5C1</accession>
    <name>A0AAD8Y5C1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009870</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5C1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="72"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="202"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="322"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="570" mass="65657" checksum="065B8540F9E97B12" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5C6</accession>
    <name>A0AAD8Y5C6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Proteasome subunit alpha type-6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_010001</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5C6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03754">
        <property type="entry name" value="proteasome_alpha_type_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000055">
        <property type="entry name" value="Proteasome subunit alpha type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034642">
        <property type="entry name" value="Proteasome_subunit_alpha6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 8 10" id="KW-0647">Proteasome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="9">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1739458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="247" mass="27010" checksum="3E6372D3B4EF075F" modified="2024-05-29" version="1">MSRDSNYDHHISIFSPQGRLYQMEYAFKAASSASGLTGIALRGSDTAVVVTQRKVPDRLIVPDSVSHVFNITPKIGVLATGMIADCHSAVQRMRYEAADFEFKYGYAIPPAVLAKRMADLAQVNTQSASMRPLACVLMIVGVDEETGPTVLKVDPAGHYLPFKGTASGAKEQEATNFLEKRVERIENYTFEETVRTAIVCLGSVLGSDFRGNEIEVACVQGKEGRFRCLTEEEIEEHLNAIADDADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6E5</accession>
    <name>A0AAD8Y6E5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008681</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6E5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47443">
        <property type="entry name" value="ACYL-COA N-ACYLTRANSFERASES (NAT) SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47443:SF3">
        <property type="entry name" value="GCN5-RELATED N-ACETYLTRANSFERASE 4, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042019576" description="N-acetyltransferase domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="212"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="394" mass="43967" checksum="3F8B941307C0F4B6" modified="2024-05-29" version="1">MKRWTVLTAATSCAIITSSSSCCCHAFAPPIHLDGSTFRSSSAAATTTTRVFLFDLKQRLNNQQRSLQQQQSRSRIPEEELYYLSRGFGFSSEEEEDFNDPLQLPYTIDLTASRSTRISDTNTENQAATSRLLLRHLEAEDIKSVLPEVVREFGAYEAPTSTGSKLGDEVATWIENFLFSFTVLVGLDQRVERRKKGYSANVPPDHNVVCLVEVTPVTNNNSDDAATTVSYTEQIVGIAELSWQPPDPTRNAPPFVLPYFAKDIISRFIPSNGGATNDKEDERKVPKGYVSNVLTWKSRRGLGYSRVLMAALEGIARRWGCDDIRLHVDADEVSGKVARGLYWSLGYEAVPDRGNNRVGYEWMGPSMANRGLYLVEGVPLLYLRKSLNEDVGMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6N7</accession>
    <name>A0AAD8Y6N7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_008982</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6N7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="37"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="83"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="98"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1740032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="142" mass="16181" checksum="FE6E070A32D2590C" modified="2024-05-29" version="1">MSKMRLFDCEESGCRCIRCMTKERMSSKVEDDTLFKCDECRTAKIKCHNPGCNNRFKFTCTRCGKANYCSKECQVAAWSLHKPECQKKKKSSKASASGEKKQKGSTRTDKVSAKMKRDEAKEMVGDLKNAHATYGHDKEEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6R7</accession>
    <name>A0AAD8Y6R7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alcohol dehydrogenase class-3</fullName>
            <ecNumber evidence="8">1.1.1.284</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_008647</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.284" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6R7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051903">
        <property type="term" value="F:S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046294">
        <property type="term" value="P:formaldehyde catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08300">
        <property type="entry name" value="alcohol_DH_class_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.180.10:FF:000067">
        <property type="entry name" value="alcohol dehydrogenase 1-like isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000003">
        <property type="entry name" value="S-(hydroxymethyl)glutathione dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014183">
        <property type="entry name" value="ADH_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02818">
        <property type="entry name" value="adh_III_F_hyde"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43880">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43880:SF12">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE CLASS-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="7">
        <location>
            <begin position="107"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="6">
        <location>
            <begin position="280"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1740552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="453" mass="48535" checksum="24AB53AC3964D78E" modified="2024-05-29" version="1">MTTFCQEGNSFLKFVEAAKKVGQKVTLNMRDGYDHSYYFIASFIGDHIAFHAKRLRSKYAEILALESSSSLDFSVTTGKTITCQAMVARAPKQPLTLETITVDVPQKGEVRVKVMANALCHTDVYTLDGHDPEGLFPSILGHEAGCIVESVGEGVTSVKPGDHVIPCYTPQCAAPACIFCQSPKTNLCPVIRGTQGKGLMPDGTSRFKDKDGNPIYHFMGCSTMAEYTVLAEISCAKISKELPLQKACLFGCGVSTGLGAVWNTCKVEPNSSVAVFGLGAVGLAVIQGAKMAGAGRIIAVDINPDKFPAAAGLGATDCVDSSKLDKPVQNHIVDMTQWGVDYTFDCTGNTNVMRSALECAHRGWGTSCVIGVAASGHEISTRPFQLVTGRTWKGTAFGGFKSRRDVPLLVQRCVDGSLEVDHFITHTFDGVDKTNDAIETLHGGNCLRAVVRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6W8</accession>
    <name>A0AAD8Y6W8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009248</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6W8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="175" mass="19433" checksum="27AE45DB61452B73" modified="2024-05-29" version="1">MSSSASSTRHLAEIVITAAESESNQKINEHSANIAQLRISNMQLHGRDDDIKLLRRKLRELAKKKEDDDEDTAKNHVSEMMMMTSSNEPDPNKQSNISNLILVSGTSGTGKSALIHKGLGDHAAKRGYTFASGKFDEKLLRPLSAFSDAMSCLSKYITEEHNKMGCYGRDRLLQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6X1</accession>
    <name>A0AAD8Y6X1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_009084</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6X1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051826">
        <property type="entry name" value="E3_ubiquitin-ligase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765:SF434">
        <property type="entry name" value="GB|AAD18119.1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765">
        <property type="entry name" value="RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="214"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="180"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="302"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="43"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="82"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="182"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="302"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1740134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="347" mass="37304" checksum="128F4212799AF2D5" modified="2024-05-29" version="1" fragment="single">FVNSSEGGEGGDIELGNIHTVQNETDGVDNKAGEDYDDEALKSISNQDATVNEGSQVMKSDIDAESPPPMNGGNEEESCQQTTADETSDEATTANNAPDSTITTLESTMSTALQPTDHQAVDAINTQSSLLPSAAADNTATTSNNNILSLYQTDDLYDDDDDDDNKYGALCLPCSSTHKDATTTPPLSVAQSAPPPQSAIGNTEPSTRLVPSTCAICLLSYSPGCYVTWSSNPECIHVFHRDCILVWLLKKEEPLCPCCRREFVSTSALNAETTTAAAAAEPDNEDSRLEQYRRSIMLLERSQSMASRRRTSSSSGRSARFARMSLQEPGATSPQWDSVGLGRVRHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y769</accession>
    <name>A0AAD8Y769_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y769"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="224"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="316" mass="34371" checksum="1BDD59850CE4F9A5" modified="2024-05-29" version="1">MGRKKKPRVEQQAPAVAEDNSTPMSMMIPKKERALPSSSTTAAPPPASVLMPPPRTGAIPSFPPPPASLPPPPSNTVNTETTANSSNNNNNMVESDPTNTSSSNNNQSSKIKSATLQTKSQEIIDEADLGTKPSSQYGLHSHSGDLIEEDIYVSDGSLSSQDDNEEEDQEEDNGADNEADKKDGNKQPELVITTSKMGLMRRGGISSLLNTQVNRTWVRDDKTTTNTSTTDDNNNETTNNEQPPEEEITDPAQLLLLQQQKIEAAKQSARILESSENAGRDPCLFSKRTAFDIRMDQIEDKPWTTGGDFTIISIMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7H8</accession>
    <name>A0AAD8Y7H8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Chlorophyll a-b binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_008245</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the fucoxanthin chlorophyll protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7H8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030076">
        <property type="term" value="C:light-harvesting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5" id="KW-0437">Light-harvesting polypeptide</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1740993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="118" mass="12366" checksum="5AA24FE50F2A476D" modified="2024-05-29" version="1">MMPTKSVSTVSLRRAQARRISQLAFLGQITTRAGVRLPGDIDYSGTSFADIGEGWSGSLQVPVAGALQILAFVGALELGVMKDVTGENEFVGDFRNGALTSAGTPLMKRPSSPSVPLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7N8</accession>
    <name>A0AAD8Y7N8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_007787</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 5"/>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7N8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43811:SF19">
        <property type="entry name" value="39 KDA FK506-BINDING NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43811">
        <property type="entry name" value="FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042216332" description="peptidylprolyl isomerase" evidence="6">
        <location>
            <begin position="19"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="7">
        <location>
            <begin position="78"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1741309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="203" mass="22114" checksum="88FF6EAA8E511D4F" modified="2024-05-29" version="1">MKQPIFLLPLLLLSSATGFVTPSATSSTRQHHLIVPQIISSSSLKLGSFDEYSQTDPDQDLAYEDTLVGTTDGVAMEGKFVTVAYKGQLMSNKKVFDEGQISFRLGDNKVIKGWDRGLIGMKVGGKRVLKIPPQLAYGDRGAGDVIPGGAHLQFDCELKGIASNAMEEKMAEASSMNPSKVFFYVFVAGSIIYDVLKYQMHVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y870</accession>
    <name>A0AAD8Y870_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione S-transferase family protein</fullName>
            <ecNumber evidence="4">2.5.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_008862</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y870"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00299">
        <property type="entry name" value="GST_C_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43969">
        <property type="entry name" value="GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43969:SF9">
        <property type="entry name" value="GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="37"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="126"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1740767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="261" mass="28967" checksum="DC21C07EF37D213A" modified="2024-05-29" version="1" fragment="single">LLEDPTVGITYYSSILILILPPILFETMSCCSADGTQKMKLHVLPVSANSHGVLAIVKALGLEDKGLEIVDAMGKTRTEEFIAMNPCHCCPTLEFGGDKGAIWESCACMRTICQLFEGGEKYYPKDPIMRGKIDLVCDWKNTSLYPPFYHIAYVMFGVAVDEAKAKEDFKKLCDEHFPVLLDTFLKDTKFCYSDTPTIADLGVAPLFTLIKCRPKFWAAVPEGVKEYHARVIEAFPEADEYFKMLDGFAAGFKGDGADAEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y896</accession>
    <name>A0AAD8Y896_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y896"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="403" mass="43604" checksum="312BBE6BC41F1CCD" modified="2024-05-29" version="1">MASANDSSKRRRLLGGASPDAGCLSELPNGVLTNVANYLDAPSRLFFAAALTNQNAVASDERNTAIVGNEWTTLDFGDIEKDLAVKLSDGDINAVLMCIDAVNRVKKLKLTNCINITGAGLEPLRRSTIIEQIDLSLVGKHQSPRLGTRPPISCKLVLPILDSIIEREGCSLRHLQFPSVHITMAAANVSNKRKRFEGDASLDANCLSDLPSGILTHVANYLAPPSRALFAAALANQNSAASDERNSAIVGNEWTTLDFGDIEKDLAVKLIDAVISAVLMCINAVNRLKRLKLTNCINITGAGLEPLRGSTIIEQIDLSLVGEHQNPNIYPEPPISCKLVLPILDSIIEAEGCSLRHLQFPSVWSAWGMVDYEQILRRYNEMLRMGAGVVAAMEVKSTRAMNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8Y5</accession>
    <name>A0AAD8Y8Y5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_007280</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8Y5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044624">
        <property type="entry name" value="Mbb1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44917">
        <property type="entry name" value="PROTEIN HIGH CHLOROPHYLL FLUORESCENT 107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44917:SF1">
        <property type="entry name" value="PROTEIN HIGH CHLOROPHYLL FLUORESCENT 107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="SAP" evidence="3">
        <location>
            <begin position="177"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="406"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="13"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="134"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="579"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1741707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="907" mass="102154" checksum="B8F146BA2F1D5697" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9Y9</accession>
    <name>A0AAD8Y9Y9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mannosyltransferase</fullName>
            <ecNumber evidence="8">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_007240</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Endoplasmic reticulum membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the glycosyltransferase 22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9Y9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000026">
        <property type="term" value="F:alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005599">
        <property type="entry name" value="GPI_mannosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760:SF4">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03901">
        <property type="entry name" value="Glyco_transf_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="2 8 9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="301"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="367"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="395"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="435"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="458"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="489"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1741667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="696" mass="78959" checksum="44E095670BC75072" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAA6</accession>
    <name>A0AAD8YAA6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007088</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAA6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="378" mass="43127" checksum="7B86321D5C97CEE8" modified="2024-05-29" version="1">MEIGNLNKNGSTNDDTLEDDEYEPIISTPSVRSKGEKLGVRVSVNQHKIEALKWISSVLATAVLLCSAKDMFGVRMNREETVAVQDLEGGVVSSIKQQQIAIKQQQIANYIKGTAIIRNIHITHHAGTSLCGQMSKVSNEHTPGFACMKKGRNNDTYWPEEAIKASPFDGKHQVGKEVSYNETKEWVSFWRQYYHFVSGEYPDWDKTLHQTNWEYENLVSMIVMRNPLERFLAGGKCGGFQTKIPDDPSNETQDTYWEYANSECADNYALRVLTREPCVQGANTSSECLQGAKDLLNRITFILDQSCLNESVEAFGSALHLNFTKDGFESRLHHWHANLSVRDRFGNDTLYEYVQTRFRRDIELYEWSKNRSIVLCNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAG4</accession>
    <name>A0AAD8YAG4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_006433</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAG4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1742836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="338" mass="37872" checksum="357A6A195984DCBF" modified="2024-05-29" version="1">MSSENKGAAATPAAVNEGDIRDDYLNNFHRTCSPSKDNDHRSLKAQLQGMNINDNDNCSTRNIADVPIEAMKHVASFLAVPSRALFAVALDKNLSRRECQAIAGNQWTTLDFGTVEKSLAEKLTDDHISAVLLCIDSVRTIKTLRLANCINITGVGLAPLRGSRVVEHIDLSLVPDHTSPLLDPAPPISQELVLPILNTIMGRGRLKVIDHARELELLQRHDEHHPFNQFLDLYMLSMNHGRGFRCKECEDEVGPNFSGEAQGTQCFVCYNCHDNYCEECIETTDLSMFCDKCERHYCDKCMESTWCECCNSSYCEKCEPLIYCRECDAQICSDCIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAS1</accession>
    <name>A0AAD8YAS1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methyl-CpG-binding domain protein 4-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006586</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAS1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045138">
        <property type="entry name" value="MeCP2/MBD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15074:SF0">
        <property type="entry name" value="METHYL-CPG-BINDING DOMAIN PROTEIN 4-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15074">
        <property type="entry name" value="METHYL-CPG-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="233"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="240"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1742989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="272" mass="30998" checksum="00142AF7D25CC364" modified="2024-05-29" version="1">MSLDLVDSDSLIHIIQYCQAEEAARVGLCNEKWNDKIFQGGKLWKTFATTRWGDGVSLVDSDEEQSTTSYSWYEYYRHRCSWMSLPGQKSKLDLIQEDYGHDPYKLLSACILCSRTSGSQTVKDVVKAFFDKYKTPSDILSGDIATIEKELKPLGLNRENTMKKFAQGFLRPWTQVSELHGCGAFASSSFDIFCRGDFKKVLREKKCDKNVRAYASYLQRVVDQTDEEVDVADNSNAAGKVKRKAKQKKTQPRKRVTLSTRKGPRRKSPRGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAX3</accession>
    <name>A0AAD8YAX3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006384</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAX3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33683">
        <property type="entry name" value="1, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33683:SF46">
        <property type="entry name" value="SUSHI DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042080894" evidence="2">
        <location>
            <begin position="27"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="211"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="269"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="336"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="434" mass="44611" checksum="167AD8ADF6C4339F" modified="2024-05-29" version="1" fragment="single">MRKNLLKDLAIFAFLALANGPSACEATASLSTNFAGTSIMEGDIWTITTGADGVSIEQLAIHMDSNTINIEVYSRPGEAHTEYEASYQKVLDEMVTGQGQGVATLLSPFGSPIDIPPNSSHTFYTTGTDDPLSIYYTDGSSVLSTFASDPYIDVKEGYSVRFPFNVPRSPTQWNGVVYYSVAAPAPSPSPPSLPPTLSPIAAPPSPPPTLSPIAATYPPTASPTNESSSSPSVSAEPSSVPSLSPSKSSEPSLEPSMNPSLSDKPSFEPSMSPSLSGAPSESSAPPTASPTNESSSSPSVSAEPSSVPSLSPSESSEPSLEPSMNPSLSDKPSFEPSMSPSLSGAPSESSAPPTASPTNESSSSPSLVPSMSSSSPSLVPSMSSSPSSEASLTPSQNPTNTSMKPSMHPSLEPSSLPTKILPQPTSIPSSQVSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAZ6</accession>
    <name>A0AAD8YAZ6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zeaxanthin epoxidase</fullName>
            <ecNumber evidence="8">1.14.15.21</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_007328</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.15.21" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAZ6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052662">
        <property type="term" value="F:zeaxanthin epoxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46496">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46496:SF1">
        <property type="entry name" value="ZEAXANTHIN EPOXIDASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042082278" evidence="6">
        <location>
            <begin position="24"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="154"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="500"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="88"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1741755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="617" mass="66106" checksum="D24B2FD2ED90962D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YB04</accession>
    <name>A0AAD8YB04_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NADPH oxidase</fullName>
            <ecNumber evidence="6">1.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_006993</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.3.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YB04"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000001">
        <property type="entry name" value="Calmodulin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF153">
        <property type="entry name" value="SUPEROXIDE-GENERATING NADPH OXIDASE HEAVY CHAIN SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="279"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="4"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="24"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="60"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="96"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="5">
        <location>
            <begin position="359"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1742428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="541" mass="61007" checksum="76E40F9136873A24" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YB53</accession>
    <name>A0AAD8YB53_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Ion channel Pollux-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_006570</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the castor/pollux (TC 1.A.1.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YB53"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044849">
        <property type="entry name" value="CASTOR/POLLUX/SYM8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010420">
        <property type="entry name" value="CASTOR/POLLUX/SYM8_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31563">
        <property type="entry name" value="ION CHANNEL POLLUX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31563:SF10">
        <property type="entry name" value="ION CHANNEL POLLUX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06241">
        <property type="entry name" value="Castor_Poll_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22614">
        <property type="entry name" value="Slo-like_RCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="TrkA C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="253"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="10">
        <location>
            <begin position="346"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="CASTOR/POLLUX/SYM8 ion channel conserved" evidence="9">
        <location>
            <begin position="448"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF06241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF22614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1742973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="845" mass="93678" checksum="A1F375E48C4A0D0E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YB62</accession>
    <name>A0AAD8YB62_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_006817</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YB62"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06171">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.601.10">
        <property type="entry name" value="RNA Polymerase Primary Sigma Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050239">
        <property type="entry name" value="Sigma-70_RNA_pol_init_factors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30603">
        <property type="entry name" value="RNA POLYMERASE SIGMA FACTOR RPO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30603:SF47">
        <property type="entry name" value="RNA POLYMERASE SIGMA FACTOR SIGD, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="Sigma2 domain of RNA polymerase sigma factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="Sigma3 and sigma4 domains of RNA polymerase sigma factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA polymerase sigma-70 region 2" evidence="8">
        <location>
            <begin position="447"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase sigma-70 region 3" evidence="7">
        <location>
            <begin position="537"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase sigma-70 region 4" evidence="9">
        <location>
            <begin position="639"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="158"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="215"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="586"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="133"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="307"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="319"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1742252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="705" mass="77988" checksum="FB09A50F6919E06D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBT3</accession>
    <name>A0AAD8YBT3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phospholipase/carboxylesterase family protein</fullName>
            <ecNumber evidence="4">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_005873</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBT3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008474">
        <property type="term" value="F:palmitoyl-(protein) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050565">
        <property type="entry name" value="LYPA1-2/EST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655:SF17">
        <property type="entry name" value="LYSOPHOSPHOLIPASE-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655">
        <property type="entry name" value="LYSOPHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
        <property type="entry name" value="Abhydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phospholipase/carboxylesterase/thioesterase" evidence="3">
        <location>
            <begin position="39"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1743252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="256" mass="27632" checksum="220FA5C7D60C8631" modified="2024-05-29" version="1">MLVRPLLFSSAAIAGRSLPLTTAMSMSSTTSGDQQCGGKSAVVFLHGLGDSPAGWSSLEHQLPSLKPSLGQDVHYVFPPAPTIGITINGGYEMPGWFDLFDWPIGISAKDDKTGKNKAAQQIEEAVEKLEKDMGIPPNRVVVGGFSQGGAVALLTAYHRRKEGKVPFAGCVCLSGWLTMKDDLEITDEVIKSTPLFWGHGQADDKVLYEQQPHGVQILRELGVDVSDAAYPMGHSSHPKEIEAMAEFLERVLKKDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YC60</accession>
    <name>A0AAD8YC60_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">glycerol-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="6">1.1.5.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">QTG54_006461</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Polyol metabolism; glycerol degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the centrin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.5.3" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YC60"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004368">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000178">
        <property type="entry name" value="Calmodulin-2 A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.870:FF:000001">
        <property type="entry name" value="Glycerol-3-phosphate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.870">
        <property type="entry name" value="Alpha-glycerophosphate oxidase, cap domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031656">
        <property type="entry name" value="DAO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038299">
        <property type="entry name" value="DAO_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000447">
        <property type="entry name" value="G3P_DH_FAD-dep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985:SF15">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16901">
        <property type="entry name" value="DAO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01001">
        <property type="entry name" value="FADG3PDH"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0106">Calcium</keyword>
    <keyword evidence="10" id="KW-0274">FAD</keyword>
    <keyword evidence="7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="12" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="EF-hand" evidence="16">
        <location>
            <begin position="715"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="16">
        <location>
            <begin position="751"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="16">
        <location>
            <begin position="800"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="16">
        <location>
            <begin position="828"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="92"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1742864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="906" mass="100846" checksum="7041408F948AA55D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YC91</accession>
    <name>A0AAD8YC91_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MAP3K-like serine/threonine kinase</fullName>
            <ecNumber evidence="7">2.7.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_006404</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YC91"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF288">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="115"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1742807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="509" mass="57209" checksum="E1275EAF0B96C07F" modified="2024-05-29" version="1">MKPGRRKTVEELKDVLSPTTHKPSSVEEEMNATSATHRVLTPLEALEREEEPEESPPAVNPAAAASNGPELDISLRIHEKVASVASKAYRKASAKSGVLSSNKVAGVGLVKFSHIEVGQLLGKGSFSNVYEITKICSTLPGATSDEDDCPEELRNVTYTDKDADNGDPRDHLEKNYERRSSRTFRYAIKFLKDDILSNPNSYAVGTVDLVIEGMFLASLTHPNIIKVRGLPEGGVNSLLQPNAKGYFLVLDRLFDTLEKRIYESWQEEHRVEDTGGGGGCFCFGNKNKQAIEDEKKYLGERLKVAFDISAALKFLHNKNIIYRDLKPENLGFDVRGDIKLFDLGLVKELDPKKMKKDGNYKLSMAGTPRYMAPECGKRKRYNLSADVYSFTMLLWEIITMRQPLEDFTYSRLQAEVFEDGHRPNIKLITNKHMRELVRLGWHQDSSERPSIDTVYEELKLEIMVLQGKKATDKALSHDRRRSTHVPGRLSTVDVSALLRSSCADLTNED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDA0</accession>
    <name>A0AAD8YDA0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDA0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF150">
        <property type="entry name" value="OXIDOREDUCTASE TDA3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="1">
        <location>
            <begin position="56"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="157" mass="17188" checksum="64FDCEABB4B69777" modified="2024-05-29" version="1">MQRRLRQDIHNLLNQPIKIDDMYCSSVGANMARIAGFGELVGYRDKATNVPSLAPKVLTRYGKTLFPESNIKEANALQCFRPLSPDDLPIVGAVRSVPGVFVHSGHGTLGWTLCLATSECLAAALTDEIIGIDTQKIFHLPGDVSVERARLSPDRFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDC1</accession>
    <name>A0AAD8YDC1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005998</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDC1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="56" mass="6299" checksum="2C0C2E4223A40EEB" modified="2024-05-29" version="1">MRPTIFDGGQIPKTGERLKRSGVTGFLWKMSRIGERLSPYVGVSCAIMAIHILFFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDC6</accession>
    <name>A0AAD8YDC6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histone deacetylase</fullName>
            <ecNumber evidence="3">3.5.1.98</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_005812</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histone deacetylase family. HD type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDC6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000118">
        <property type="term" value="C:histone deacetylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141221">
        <property type="term" value="F:histone deacetylase activity, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040029">
        <property type="term" value="P:epigenetic regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF5">
        <property type="entry name" value="HISTONE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="SANT" evidence="13">
        <location>
            <begin position="111"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="14">
        <location>
            <begin position="114"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="12">
        <location>
            <begin position="114"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="10">
        <location>
            <begin position="560"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="10">
        <location>
            <begin position="604"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="10">
        <location>
            <begin position="637"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="78"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="207"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="394"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1027"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="88"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="222"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="410"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1048"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1060"/>
            <end position="1086"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1743191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1239" mass="132352" checksum="9AE392B9C060EC46" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDV8</accession>
    <name>A0AAD8YDV8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005244</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDV8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1743647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="207" mass="22571" checksum="0D2D72D9D86AB404" modified="2024-05-29" version="1">MLATKLSSALVAPSKVANTLDWRKAFGAVMGIDVTRDRIGLAIVEHPEHICESVPLKSIPLHDTADMKKAGWVRTVEGTTCTRSVINRSNSIISRKRPFTLWGSSANGSFASFPTDSWGRSVEFARAPAYTPGMSFSSKSVSRQEPSYDPSLVAASVLDEWVEKHWQIDSKLGIATAPKLTSKNLFFDPSSVHEYNSESASLQAALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEC5</accession>
    <name>A0AAD8YEC5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005165</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEC5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="84" mass="9333" checksum="44D7A57E606F7B8E" modified="2024-05-29" version="1" fragment="single">MSGGIFLSGKFDQLQQGKPFSALASAFNGYCGMLMQSSELQTRREVVASKLRSSLGREVYYLTKIIPCLNHILGSEQSDDTFYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEM9</accession>
    <name>A0AAD8YEM9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006206</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEM9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052592">
        <property type="entry name" value="LRR-RLK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48054:SF94">
        <property type="entry name" value="LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN FASCIATED EAR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48054">
        <property type="entry name" value="RECEPTOR KINASE-LIKE PROTEIN XA21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="361" mass="39697" checksum="F33EAE16A8C54C1E" modified="2024-05-29" version="1" fragment="single">DNPPWFLPLLVLVLVACVILAIVLPPSLRGELGNAAQDMSSPLSDAVCLPGEVEARLELAKSILSSITPPDLLEDGSTPQGKAIRWIVCDDSISVQLLENQEHATGNLSKQKHGFRFGGDAGEAQVTRRYILAAFFYSTSQSSPWKDSLNFLSPDLHECNWHKNFTKQNNFPFGDFDPVGVFCIIDKGELSSPISITEEFLLNDDDYPLRYLELHFRIENNLNGPLPPEIGYLIDCKGVGFENNIRLTGSLPQTMGNMTSLFSVSLLLNGPNFGGELPSSLFQLKNLIYITIMSNLGKDWSLPTNAQVGDDTQLEQIVLVRNNFSGAIPSWIAKLEKLQTLDLSMNNFQGAIPEAIGDLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEY0</accession>
    <name>A0AAD8YEY0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004852</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEY0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032299">
        <property type="term" value="C:ribonuclease H2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.680">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013924">
        <property type="entry name" value="RNase_H2_suC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47204">
        <property type="entry name" value="OS02G0168900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47204:SF1">
        <property type="entry name" value="RIBONUCLEASE H2 SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08615">
        <property type="entry name" value="RNase_H2_suC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="225" mass="24298" checksum="D4C2F8F6902E2CD3" modified="2024-05-29" version="1">MSSAQTRASGGGTICHILPCSIDEDITAPVAQYFHPTPLTTTHNNPADGDSKDSSTSDVTIMAAQFRGRGLLCATDAKHESSSNDIATGKVYVDLTNEGQSTADGEAANTDDPSSTSLSPLKQSYKRPLSKLPPTMAGVVFNHTQTSTNNQHNNHNNNNNKDPPMQPLTTIETFSHIYNWRHEHDETKVMRESTFGSSDKEGLNAVLGWCDVAHAVHDAVPLPQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFF8</accession>
    <name>A0AAD8YFF8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_004634</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFF8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051012">
        <property type="entry name" value="CellSynth/LPSAsmb/PSIAsmb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45586:SF1">
        <property type="entry name" value="LIPOPOLYSACCHARIDE ASSEMBLY PROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45586">
        <property type="entry name" value="TPR REPEAT-CONTAINING PROTEIN PA4667"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="577"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="744"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="148"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="428"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="843"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="154"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="179"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="862"/>
            <end position="883"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1745343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="920" mass="100301" checksum="1927A2793593D93C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFL6</accession>
    <name>A0AAD8YFL6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L32</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_004849</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFL6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00513">
        <property type="entry name" value="Ribosomal_L32_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001515">
        <property type="entry name" value="Ribosomal_eL32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018263">
        <property type="entry name" value="Ribosomal_eL32_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036351">
        <property type="entry name" value="Ribosomal_eL32_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23413">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L32 AND DNA-DIRECTED RNA POLYMERASE II, SUBUNIT N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23413:SF1">
        <property type="entry name" value="RIBOSOMAL PROTEIN L32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01655">
        <property type="entry name" value="Ribosomal_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01393">
        <property type="entry name" value="Ribosomal_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52042">
        <property type="entry name" value="Ribosomal protein L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00580">
        <property type="entry name" value="RIBOSOMAL_L32E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1744316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="136" mass="15471" checksum="59661F163B71A338" modified="2024-05-29" version="1">MAGVQPLMKKTIVKKRTKKFARHQSDLFMRIQRSSWRKPKGIDGRVRRRFKGALPMPSIGYGSDKKTRNTLPCGFKSVLVSNVSDLEMLMMHNRTYAATVAHSVSSRGRREIIERAEQLAIRVTNAAAKLRDEEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YG53</accession>
    <name>A0AAD8YG53_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004123</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YG53"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="125" mass="14353" checksum="AD95CBD0476D0332" modified="2024-05-29" version="1">MIDLPVSELRLSSTDDTKPHKISEEELATLARRCLIDVRRLSPDRRDQLRVDIAGIMRCASVMLDSKKLGIDGDNNDASLDNTLTDQEVYDDPRGLGRMPLRRNSLETEQRDEWKLNGSKNPRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGD0</accession>
    <name>A0AAD8YGD0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Mitochondrial carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_004345</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGD0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="83"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1745054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="200" mass="21847" checksum="3A018CD57A8BA028" modified="2024-05-29" version="1">MGAATFCHPLDVIRVQMQTDGVAYKNTFDAATKIYHELVLLKGVSAAYLRQWMYGSFRIGIYAYLLEQTQLQNVANGKNKNDISFGQKLAMGCCSGGIGSFIGTPSELALVRMSGDNKLPPAERRNYSNVIDCIARIGKEEGITKLWRGATPTVLRATLLSSAQLGVTSEIKGHLAKADGLAKRRLLLWLANDVLLDVVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGV4</accession>
    <name>A0AAD8YGV4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycosyltransferase (Family 92)</fullName>
            <ecNumber evidence="6">2.4.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_004378</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 92 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGV4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008166">
        <property type="entry name" value="Glyco_transf_92"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01697">
        <property type="entry name" value="Glyco_transf_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1745087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="314" mass="36526" checksum="B3345C0ED9A1B0B4" modified="2024-05-29" version="1">MKGDKSYHEHYYERGEKYTSPFSTNGDRFRTLLILCEELRYDRSLSRHPPLTLSSDDGTFHLRIGSSFARPVAQTRKSDWSAKASGQYTTRITYEHAKWAAQTDCALRSRGLYDYALFSDIDEVAMGGNEGLAPALEMCEQAHTDRGVIGCSFNSNTVSSVFTKLTDEEEMKMKDKLLLERYSNVEAKPFCPSNCKCLGRNCKEMTRKYHYGRQKYMLNMHDLTIPPRPLWTHAIARDYNEMDRIMEQLPDDVFHIRHYQGHWLKNNNLLDTMEEKNAPLPKEFIDLLRETIFENSLHCEEGMQKHKKIPFLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YH27</accession>
    <name>A0AAD8YH27_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YH27"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042226621" evidence="1">
        <location>
            <begin position="20"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="181" mass="19300" checksum="6105D959DEC626F0" modified="2024-05-29" version="1">MKVLLLLLLASSVLTCTLAFAPSPMSKILQPSADAETTVLFMLSSDTDDEGVCHRRDLLLRTGSFVVASMFGLDGVEPAEAIPEQKVYSSNAKNFQRLGEGDSSGGSVYDNNPTSPKARARRAMVGCKNNSARSLAGESIGNTRLSEKDCNQLVMKGDGGFMLEALTKLDCPSCPYGIGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YH56</accession>
    <name>A0AAD8YH56_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002634</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YH56"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="203" mass="23660" checksum="602AA53BDA819782" modified="2024-05-29" version="1">MKWCRLNCLYCRTLPALSRPLANILHHKTKGNPLFVKQVMLELYKQRLLYPSLSRRRWRWRWVWEADKILDMKIPENVATFITNSFDRLPFEVVSALVILSCFGASADISLMEVLEREIAPLDEAVAHSVLGKRNGEFYFMHDKLQEAAYSKMKPEERCLHHNRYGLALGFVAARERDDRVLLTAVSQINHGDRTQSLMKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHU6</accession>
    <name>A0AAD8YHU6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHU6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="119" mass="13164" checksum="81B83ED4AD058B98" modified="2024-05-29" version="1">MSASELLAKQGWSSKQQFAAPTNDETATLSSYDMKYSSISPPEQRCPSARTITNQCFTTLDESVDEASLSSESFRIKEEMNTVYDSSPMAPSYIKSPSKHSSMDEVIVSTKTHQSHLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YI83</accession>
    <name>A0AAD8YI83_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_003489</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YI83"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000007">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001148">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15/PRP43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1080:FF:000003">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF109">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="64"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="241"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1745565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="719" mass="80399" checksum="8C0C4DF717D733FC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIB9</accession>
    <name>A0AAD8YIB9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Vesicle-fusing ATPase</fullName>
            <ecNumber evidence="7">3.6.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_003746</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.6" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIB9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005795">
        <property type="term" value="C:Golgi stack"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035494">
        <property type="term" value="P:SNARE complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000154">
        <property type="entry name" value="Vesicle-fusing ATPase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039812">
        <property type="entry name" value="Vesicle-fus_ATPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23078:SF3">
        <property type="entry name" value="VESICLE-FUSING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23078">
        <property type="entry name" value="VESICULAR-FUSION PROTEIN NSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="165"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="343"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="353"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1745822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="445" mass="48399" checksum="5FE5488E093B2867" modified="2024-05-29" version="1">MGPAMIIEWTLMPKISGLQVDESVSGAKRKGDMILRKFAWKPQNMFNFIDDDIEQPETKAKEQEANFAGAISLSGSDRNEAFTSGFQQRVGGLGKQIDAIVRRVLDGRVIRPAEMDENGNLLSYKEAKQHTGAEGDELGYLDNASKQLSLAALEAEELSLLGLTPVRGLLLYGPPGCGKTALAREIAIALCARAPKIVSAPELLDRWVGGSEKLVRELFADAEAELAACGGDSTRSALHVIVVDEIDAVFRKRTSAEDSGEATRSSTVNQILAKLDGVEAIPNVLLIGMTNRRELLDDALLRPGRLEVQIEIPLPDKLARREILRIHFGALRERGRLSQPLCHAIDGPATRSRNSDEIDSSEKRGKKRRKLKNATYNIIDYLSSASTKNVDLADETHGFSGADIEGLVRCAGSIALSRARRDGGGVESLLITLDDVQQALLEVKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIE6</accession>
    <name>A0AAD8YIE6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003264</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIE6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="251"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="367" mass="40676" checksum="93EC3B66A04A29CF" modified="2024-05-29" version="1">MVVGSSNPPLQVVLGSRASSDSSATQCAAESSAIRSNSTAYILGTSASRLGSGLKLKIDGRVPMEDRKAPLSQFRLKSLLLSTFRVVAINISSTLSTYFSDQLTSEQDNEKLVDDGEITPYEADEMNEEWESREWQKRMDILPKKIGYALLRFHACTALMRFYELIIGRYILCVDGNARLESGSIPGRDNSTYEHSVDVMDKLTRDPFQASLRTSQILHNQEHSPGKVLSSDGKETSTSSELYKQMYTTCFWANIIPFLAELTVQHGVLLYGYGVYYMEKKRRRKEREMSSSDDDEQCKDEQDETEPVDETAYALSILFRSSHLTFSRGVSLIAASVGGAVGSVIYPGWGAIFGIQIGDTSVGALLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJ21</accession>
    <name>A0AAD8YJ21_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TWIN LOV 1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_002562</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJ21"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14809">
        <property type="entry name" value="bZIP_AUREO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.20:FF:000135">
        <property type="entry name" value="Ptaureo1a lov2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47429:SF8">
        <property type="entry name" value="PHOTOTROPIN-1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47429">
        <property type="entry name" value="PROTEIN TWIN LOV 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0157">Chromophore</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="6">
        <location>
            <begin position="143"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="262"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="95"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="120"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1747218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="376" mass="39945" checksum="7CFD944B848A83A1" modified="2024-05-29" version="1">MSEATSSATKPQPGAGLVGAACAAAQPVVPVPVPSNNTSAMQFFAPDPSDERDSMQQALDLDELFHDCYFDDLTLPAPVTSTSAPIAAEPTITSAAPAPASAAPVKRSAAEAGLADKPQEVTSGGDSGSEKGTSSKPAASLTESQKIERRERNREHAKRSRLRKKFLLESLQEQIEGLQGEIQSLKDIIKRELPAKAEALLKDIDGGDNSNAAGPKKGDYTPLPMPSGFGPVKTLMEPDYRLMSALSGSQQNFAISDPSLPDNPIVYVSQGFLDLTGYTLDQVLGRNCRFLQGPGTDQAAVDVIRRGVREGTDTSVCLLNYKADGTPFWNQFFVAALRDAENNVVNFVGVQCEVSKAVVDKHIAEGKTPALESGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJA0</accession>
    <name>A0AAD8YJA0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rhodanese-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002682</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJA0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate-cyanide sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44086">
        <property type="entry name" value="THIOSULFATE SULFURTRANSFERASE RDL2, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44086:SF10">
        <property type="entry name" value="THIOSULFATE SULFURTRANSFERASE_RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="111"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="208" mass="23110" checksum="C4CEF9BCAB053256" modified="2024-05-29" version="1">MMMWRRVVVLTAASSSRTVGASSLRSSSALAFCPSNNHQSKNQHQKRRQEVTPPTTTSFLHYKQNIHERLLSTTTTARQMSFFGGSSEGIPRINKEAMTEIIDDVSSTSREESNYVIIDVRGQDEIAYTGKLNDCVETLPLPYIAQGALAMEDEDFKAEFGFDKPALDETLVFTCKAGIRSQQAGQLAKMAGYTDILDYMGGSNEWFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJB7</accession>
    <name>A0AAD8YJB7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002466</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJB7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052841">
        <property type="entry name" value="PMP_oxidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28040">
        <property type="entry name" value="PYRIDOXAMINE 5'-PHOSPHATE OXIDASE YLR456W HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28040:SF1">
        <property type="entry name" value="PYRIDOXAMINE 5'-PHOSPHATE OXIDASE YLR456W HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="121" mass="13649" checksum="A9D521012FC383EC" modified="2024-05-29" version="1">MRFTYLPEEETIVMSTNVKTKKYDMLEKQNGVALLIHDFGEGDNLTGEYSITLNGTVCVEMPTSAVVMAEKYRSAHLKNNPEYPQFIVGKDIAMLRVDVATARICNINDEVLKWNVMSGNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJK6</accession>
    <name>A0AAD8YJK6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sulfotransferase family protein</fullName>
            <ecNumber evidence="5">2.8.2.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_002616</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfotransferase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.2.-" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJK6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11783">
        <property type="entry name" value="SULFOTRANSFERASE SULT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sulfotransferase" evidence="4">
        <location>
            <begin position="28"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfotransferase" evidence="4">
        <location>
            <begin position="172"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="137"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1747272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="249" mass="28105" checksum="45490E5DD9E0BBDB" modified="2024-05-29" version="1">MMTFPPMPLLPITSQSTISACRELPLRPSDIFVCSYPKSGTTWTQHIVLTLLLADRKKLPCGNSDAGNTGDDLAYNHVSDYAPFFEIDAHWQSSPSNDGTKVLLANSVRENHDRLGRRMFNTHLRWDMLPKRCEVDGCTPQNDDKKGNDDVNTGPSDDNDSHVHKQRPQCGKFIYVTRNQIDVVASFYHHLSNQIEGTYTGTFETFLRDWMDGKIPFGSSLHHLIRFAGGFADNLYDTSCGHDDILRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJV0</accession>
    <name>A0AAD8YJV0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003027</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJV0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052591">
        <property type="entry name" value="CML21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23064">
        <property type="entry name" value="TROPONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13833">
        <property type="entry name" value="EF-hand_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="160"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="240"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="328"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="372"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="557"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="630" mass="72139" checksum="A68001553776CA0E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YK26</accession>
    <name>A0AAD8YK26_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Kinesin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_001796</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YK26"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24115:SF1008">
        <property type="entry name" value="KINESIN-LIKE PROTEIN SUBITO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24115">
        <property type="entry name" value="KINESIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0493">Microtubule</keyword>
    <keyword evidence="4 5" id="KW-0505">Motor protein</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="8">
        <location>
            <begin position="16"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="73"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="323"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="507"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="739"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="795"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="574"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="328"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="339"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="507"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="517"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="739"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="149"/>
            <end position="156"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1747833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="818" mass="91045" checksum="77BB7F0CADCF1A2E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YK40</accession>
    <name>A0AAD8YK40_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YK40"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="59" mass="6623" checksum="921E723B044EC137" modified="2024-05-29" version="1">MGNIVYERKTNGIRTELKEELLKAKEAQFALQNMLESTANKSDTPVEQDENTVDVILVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLB0</accession>
    <name>A0AAD8YLB0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_000658</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLB0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051809">
        <property type="entry name" value="Plant_receptor-like_S/T_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR27008">
        <property type="entry name" value="OS04G0122200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR27008:SF497">
        <property type="entry name" value="OS11G0695000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="123"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="55"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="135"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1748719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="711" mass="78628" checksum="8015BDD96F927534" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLK6</accession>
    <name>A0AAD8YLK6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peroxin-14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_000808</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLK6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09212">
        <property type="entry name" value="PUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006785">
        <property type="entry name" value="Pex14_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036339">
        <property type="entry name" value="PUB-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018997">
        <property type="entry name" value="PUB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23153:SF38">
        <property type="entry name" value="UBX DOMAIN-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23153">
        <property type="entry name" value="UBX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04695">
        <property type="entry name" value="Pex14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09409">
        <property type="entry name" value="PUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143503">
        <property type="entry name" value="PUG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peroxisome membrane anchor protein Pex14p N-terminal" evidence="2">
        <location>
            <begin position="59"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="PUB" evidence="3">
        <location>
            <begin position="516"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="382"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="604"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="448"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1748869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="629" mass="69097" checksum="163AEB4F748618B5" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLT8</accession>
    <name>A0AAD8YLT8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Multidrug and toxic compound extrusion (MATE) family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_000895</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLT8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044644">
        <property type="entry name" value="DinF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42893">
        <property type="entry name" value="PROTEIN DETOXIFICATION 44, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42893:SF9">
        <property type="entry name" value="PROTEIN DETOXIFICATION 46, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="295"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1748956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="332" mass="35223" checksum="352F02FF4B4694A2" modified="2024-05-29" version="1">MYAFRTPALLQLLNVDPLLRTSATSYIHWRGATAWAAMAQNVCLSLFVVTRDVITPLKIISCAAVANVVGDALFCVWPIRGGCGGAAAATTCATLISSFWMVAALRKKQLLPCLRIPKKSELASLGEFTGPLLAITLTRMAGFLNMQRRAMTLGVTALAGYQLSMNLLIFFILFGEPLSQLGQTKLPGLIEDGNAKEAMATLKSILLLSVFAAVGVGAAACLTAFLGPGLFSSDLGVQAVAKGAAPMLFLAVAMTIMGIAIDGAMMASRDFGFMLGTGIVSFFVQAKLLKYCGSVQAILATFAVRLGSYTLFSIIRAFATNLRIRKTAKQTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMN8</accession>
    <name>A0AAD8YMN8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Rhodanese-related sulfurtransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_002020</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1748057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMN8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluA-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022111">
        <property type="entry name" value="Rhodanese_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020936">
        <property type="entry name" value="TrhO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040503">
        <property type="entry name" value="TRHO_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43268">
        <property type="entry name" value="THIOSULFATE SULFURTRANSFERASE/RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43268:SF6">
        <property type="entry name" value="THIOSULFATE SULFURTRANSFERASE_RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12368">
        <property type="entry name" value="Rhodanese_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17773">
        <property type="entry name" value="UPF0176_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="279"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="115"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1748057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="981" mass="108117" checksum="07AD1236272E2801" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4E6</accession>
    <name>A0AAD9D4E6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Sensitive to high expression protein 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_016704</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Required for the maintenance of the structure of the mitochondrial inner membrane. Involved in mitochondrial morphology. Causes growth arrest when highly overexpressed.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SHE9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000062">
        <property type="protein sequence ID" value="KAK1732643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4E6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008839">
        <property type="entry name" value="MDM33_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31961">
        <property type="entry name" value="SENSITIVE TO HIGH EXPRESSION PROTEIN 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31961:SF3">
        <property type="entry name" value="SENSITIVE TO HIGH EXPRESSION PROTEIN 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05546">
        <property type="entry name" value="She9_MDM33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="265"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="151"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="305"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="350"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1732643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="434" mass="48384" checksum="1E8EC6947206E88B" modified="2024-05-29" version="1">MIRRHAAASKIVSRCILLPSSAINDGNDVLWASVACNHRCSYFSSSAPSTAGGTTTKSAPPAAINSSSSKLDHWLEAWNEHSGTHEISKLKELVHNSSLKFDKQQRLVADARKAVDHALSAWEDSQIKHAQLMQVREKWTPAQALEFAKLLEKEVQVRSNLEQAKKDLAEKETHQSKLQIDYMNNLRKRYHEEQIWTDKWRILSTYGTWGLIALNSVVFLISQYLFRVRERSRMKDFEALLKETLSSNTSTMLAIREHQNDIAEQRNESQNINEPSRQSKNGSSNEQSITVKKEEGGTVLLNTSRGEESKQQHDVCKEESADKDDSDKQEPSDSSGSENKREPSSPSSSQGKQPAPMSTLQSKLVKLDRDKKMARILKHASDVLALSWSSLQTRATAAKIDCANKVDLPSAALGACVTSVAWLVAISFSKKGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4P2</accession>
    <name>A0AAD9D4P2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Esterase</fullName>
            <ecNumber evidence="2">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4P2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050583">
        <property type="entry name" value="Mycobacterial_A85_antigen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48098">
        <property type="entry name" value="ENTEROCHELIN ESTERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48098:SF6">
        <property type="entry name" value="FERRI-BACILLIBACTIN ESTERASE BESA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041977135" evidence="1">
        <location>
            <begin position="25"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="349" mass="39738" checksum="B29AC6CB9474FCA9" modified="2024-05-29" version="1">MCIMMNLIGIISWFSCVLIWRAEAYTDSRPLLPPFPNGVCSGSVVTLPQDELYSTKSSPFNLFSSIENIMLPPRDVKVWMPAEYHKPEFRTHRFPVLYCHDGQNAMEDADSWTGSSWRLVGALTRLYERDLLRIEAPPIVVLVPCGDSFQRRHSEYGDLPHPVSQAHGDFMATKLHPYIMNRFRVKEGPEHCAALGSSLGGQASLQLLLRYPKIFGAAACLSPCFQAGTIAAVVSKSISPSEREDLRSKTIYIDNGGDVDDTRVPVIDVMDHFTMNDRWWNPGYWWLDTTLQPMIDAVRFALDQAGVQYRYEKFPGGRHNERGWAQRIHRPLLHLYGKENENESVNMFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D537</accession>
    <name>A0AAD9D537_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutaredoxin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000051">
        <property type="protein sequence ID" value="KAK1733273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D537"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008554">
        <property type="entry name" value="Glutaredoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052565">
        <property type="entry name" value="Glutaredoxin-like_YDR286C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33558">
        <property type="entry name" value="GLUTAREDOXIN-LIKE PROTEIN C5ORF63 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33558:SF1">
        <property type="entry name" value="GLUTAREDOXIN-LIKE PROTEIN C5ORF63 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05768">
        <property type="entry name" value="Glrx-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="207" mass="23425" checksum="F79175374B07C212" modified="2024-05-29" version="1">MIFSTMVSNTTTRGSRRALMSSHHHLLLLSGVASLMPAVTNAFIATNQHHHCNHHQLTTLIHRRSVHLPKRNSFQLHSSSSSSDEDQSTNSVTGPIYEMTNDNAPPPKIKLFTKEGCTLCDKVKDILSEIRTDYPHSLYAVDITDDDKQVWFDKYKYDIPVLHMEDVYWTKHRLTKEEAIQGIEEAVGGGGEFECRKGEPDAGRLEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5G8</accession>
    <name>A0AAD9D5G8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000046">
        <property type="protein sequence ID" value="KAK1733648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5G8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="275" mass="30741" checksum="45B56B24D2BD9812" modified="2024-05-29" version="1">MLMLGVKNVEYSAFYACFGLSSVEFGRDLETIGESAFDQCNSLRNIKMPNVLRIGLRAFQDCAVTELDLPLGLEVVEGQAFGGCQSLTRVSMPLKGGMIQGGAFVGCNRLVRIDLIGGIHDFVSSLHLEEWRNTMKAEISRINEDLPLINVGEVDKTRVIQEWMQSVLDRAEHYKGEHYALLKEGMTILELAVWGAKIVEAEKERDDNGDDKSTAATSSVSLEENLSEKLKIDNDGDNDGDDEWRFRQQQRGKSLANVVIHNVLPYLMCTKLDHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7E5</accession>
    <name>A0AAD9D7E5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphoglycerate mutase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_012391</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7E5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004331">
        <property type="term" value="F:fructose-2,6-bisphosphate 2-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045820">
        <property type="term" value="P:negative regulation of glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043456">
        <property type="term" value="P:regulation of pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051695">
        <property type="entry name" value="Phosphoglycerate_Mutase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46517">
        <property type="entry name" value="FRUCTOSE-2,6-BISPHOSPHATASE TIGAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46517:SF1">
        <property type="entry name" value="FRUCTOSE-2,6-BISPHOSPHATASE TIGAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042223893" evidence="3">
        <location>
            <begin position="34"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="82"/>
            <end position="89"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1736946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="184" mass="20324" checksum="1E3396D04BE150E1" modified="2024-05-29" version="1">MVVMISSTRSFLSIKGIPLFLLTFRSLVMPAASQKFIDTSAATSTVSDFGKTQAANQNKLKEDDDDSSLQFTPFTIRLHLIRHGETLANERNIVLGQGDSPLTDKGVALAGISAQSRYINGRTEAIRYWRTYTSDLYRAHRTAKIVLGLEDIHGNTKMMASSNKQHQMKEAMIPPTTSTTISIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAB6</accession>
    <name>A0AAD9DAB6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mpv17/PMP22 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_010764</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAB6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF17">
        <property type="entry name" value="PROTEIN MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042255230" evidence="8">
        <location>
            <begin position="28"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="307"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="90"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1738734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="359" mass="38459" checksum="B015003E1EF38D6B" modified="2024-05-29" version="1">MAASTTATSSSAVAFLLLFISLSPVSAGAFSCSSPSALAINKHPSRVPTVRYTGSSGGLFTTSASARIMRESPRSVLCLSELALIRGGDQNDVESESSGDTTDADINMKRVYGTNNNDNNVIDEESPSATVEMTAKSTTSLKSKKSDLTSDDVTILSSSRMALSTVLSPISSILAAFATFYTGQLTARPIITKALTAGIIFMASDYCAQLIERGGDEEEKAPLVWSRMLTNFLVGLLVFGPAANAWYSMVFKMLPSTSLFSTLQKAALGQIIFGPAFTSVFFGAGMIQAGSFSIGAWIQKVKNDLPAVWASGLGFWPFVDFISYKVIPVQWIPLFVNFCSFVWTIYLSMVSNRSRGEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAC6</accession>
    <name>A0AAD9DAC6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010794</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAC6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42044:SF2">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42044">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="428" mass="48146" checksum="72D91BAD9BF66158" modified="2024-05-29" version="1">MLLTLRTRLLSLVTTAISLGIVVAGIATQPVMSLFCGSISSTSAWILSLGAFYYGYGVGLGGYLIGGALACVVCGLAGSPLNLIKLLLGPKQPEPQVKMVKVKEASVKPKKGLVATTLWAITRRFFRLIFLVLGILDTIIHTSFLEKEKRGATKEDRNWFWNQLYEKDEDYYDYEQVYGGEVQNDHPEELWIFCNGIMNELDDAKRVCKKITELFGRPCKLLHNPTDGIILDLLECLMGKTGLFKLGCTGPRRLLRKKLGMEMEKDCYKKIVLVAHSQGTIISGNVIADFNDRIEDKEKYTEEEREVMKMNMSKLEVYIFAGAAHYMSGKYVSHLECLSNRGDVIAVCGHVFPKILKFLWRNTRGNGIIYDDHCKDHVETSNWGHLLIPHYLASLENGCFSGSKLATEYWLKNPQKKNESETSPLIPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAN4</accession>
    <name>A0AAD9DAN4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Transmembrane protein 43 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_009302</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TMEM43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAN4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005637">
        <property type="term" value="C:nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071763">
        <property type="term" value="P:nuclear membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012430">
        <property type="entry name" value="TMEM43_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13416">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13416:SF2">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07787">
        <property type="entry name" value="TMEM43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="348"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="381"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="417"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="264"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="264"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1740352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="528" mass="57007" checksum="71D31227A4EDCDCF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBW7</accession>
    <name>A0AAD9DBW7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007409</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBW7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="753" mass="85090" checksum="6AC5C25164F81FA1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCE2</accession>
    <name>A0AAD9DCE2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006956</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCE2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="108" mass="11636" checksum="6722B9FAB435961A" modified="2024-05-29" version="1">MRFRFMNQMSKSFRLSGGQSSSVGARQSTNQMTQMPSFQATVQRTLQTKSTGKVALQRRLLSGNVIQTSRAALVVEGASIVLATLEGISDPNLPRGWDAGVMDDDDGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCI8</accession>
    <name>A0AAD9DCI8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CEMIP beta-helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006957</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCI8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055401">
        <property type="entry name" value="CEMIP_beta-hel_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052387">
        <property type="entry name" value="Fibrocystin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46769:SF2">
        <property type="entry name" value="FIBROCYSTIN-L ISOFORM 2 PRECURSOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46769">
        <property type="entry name" value="POLYCYSTIC KIDNEY AND HEPATIC DISEASE 1 (AUTOSOMAL RECESSIVE)-LIKE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24606">
        <property type="entry name" value="CEMIP_beta-hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="CEMIP beta-helix" evidence="2">
        <location>
            <begin position="187"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="567" mass="62117" checksum="D043EEF80316664E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCQ2</accession>
    <name>A0AAD9DCQ2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_007167</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCQ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1742602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="551" mass="59276" checksum="F227FCD15CECD53D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCX9</accession>
    <name>A0AAD9DCX9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">methionine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Methionyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_006319</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCX9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006431">
        <property type="term" value="P:methionyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00814">
        <property type="entry name" value="MetRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.220.10:FF:000002">
        <property type="entry name" value="Methionine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014758">
        <property type="entry name" value="Met-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023457">
        <property type="entry name" value="Met-tRNA_synth_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00398">
        <property type="entry name" value="metG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43326:SF2">
        <property type="entry name" value="METHIONINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43326">
        <property type="entry name" value="METHIONYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methionyl/Leucyl tRNA synthetase" evidence="9">
        <location>
            <begin position="55"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1742722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="422" mass="47119" checksum="3931B49E768A8B93" modified="2024-05-29" version="1">MTSESKPAYDRWSLCDPSTLAYGYYSGTSNNSGVSNESPTPATIDGSAATDKKGVYITTAINYTNGPAHMGHAYEAATTDAIARFARLNSIGGNSPSSAYFVTGADEHGEKIAKTAEREDKQPIDICNTYVTGFQCLNQRILVSNDDYIRTTSDRHKRTAQALWNKCAANDDIYLDAYSGWYNVKEETFVTDSEAELCNYCDPASGQPLQRVQEASYFFKMSEYHDRLVEHITANPDFIRPEQHRNAILARLTGDRLRDLSISRTTFTHGIPVPEGFEANHVMYVWFDALTNYLTGVDVLGVCDPEKGQDEELAKLWPADVHIIGKDILWFHTVIWPCILMSAGLPLPKSVFAHGFVNDKDGKKMSKSIGNVVDPHDMLDKFDVDSFRWYLCKEAPYGGELSFSEDNMRDMHNADLCDTLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DD33</accession>
    <name>A0AAD9DD33_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DnaJ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_006484</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DD33"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051339">
        <property type="entry name" value="DnaJ_subfamily_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078:SF553">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042085672" evidence="3">
        <location>
            <begin position="20"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="4">
        <location>
            <begin position="30"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="425"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="425"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="458"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1742887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="736" mass="81638" checksum="80DDFBD59A127C54" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDF1</accession>
    <name>A0AAD9DDF1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_007532</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDF1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016817">
        <property type="entry name" value="MannP-dilichol_defect-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12226">
        <property type="entry name" value="MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 LEC35 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12226:SF2">
        <property type="entry name" value="MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042213094" evidence="4">
        <location>
            <begin position="21"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="225"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1741959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="348" mass="37745" checksum="651D8272319175BD" modified="2024-05-29" version="1">MISLFYTLTLVVATASLCHAFVTPSSLSVRHNHHQDFAFAFASKIQPATVNYLSPIPLIDESSSLILCSDGSEINPIAQTVGYLVGVGSFLLYTPIAVRLLRTKSAEGLTISTWWMKVTAFTCLDTYNIKNGFPLAAWSESLVNTVESGFVLCLVAYFQKQLNLTTFLLATTYITASSWALFAPASFGPSPEVISLAQVFSIVLNTSALLPQLKQNFERQSSGDYSTITALVACAICGTRIYTTIELANGDPLLLLNYGVLFLLNVGLLAQVLYYGTQVEGKALASLFLADIKSDDSSIEDLAKDVTMIEDADKIGSVTSNPIVAFFDKPIIKVVENAEERVSTVSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDG8</accession>
    <name>A0AAD9DDG8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Splicing factor U2AF large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_005913</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDG8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12232">
        <property type="entry name" value="RRM3_U2AF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000097">
        <property type="entry name" value="U2 snRNP auxiliary factor large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23139">
        <property type="entry name" value="RNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="91"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="213"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="27"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="62"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1743292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="455" mass="49515" checksum="EF0123E847C38C20" modified="2024-05-29" version="1">MSDYYDRDDRRRGSHRRDRDDRDYYRSSRRRSRSRSRSRSRSPSNRYSSSSGIPSAGMIPSAASQPPLSNTGGLPLDGYSTTLSAQDKINRELFVGNTPPGTSEALLMQFLSGAMRKTNLCPPDATPILACRTNQKFAFIECASVDTANKALNLNGVPFLGASLRVSRPSKYAGPHIPSLTWQQLTGQPLAPGMTPVQENGMGGGSAEEKLNRELFIGNTTPEMTEAMLRDFLGRAMEQVGLTRMPGNPIVSCRVSGKFAFVELRTKEEAENALNLNNIPYLGASLRVGRPSKYTGPHTPHGNWEDILAKFMSGELQLNNAASAPAPPAAIAAPPMAQIPAAPAMMMAPAALPAAVVPTRVVELKQMLTQQDLEDDEEYNDILEDTRDECSSFGTLKNIVIPRTGPGATKIFLEYLSVEDAGKAIAGLKGRTFDGRQVGATYFDEIKFANEDYSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDP2</accession>
    <name>A0AAD9DDP2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytosolic carboxypeptidase</fullName>
            <ecNumber evidence="5">3.4.17.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_005428</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the peptidase M14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.17.-" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDP2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06234">
        <property type="entry name" value="M14_PaCCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050821">
        <property type="entry name" value="Cytosolic_carboxypeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040626">
        <property type="entry name" value="Pepdidase_M14_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12756">
        <property type="entry name" value="CYTOSOLIC CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12756:SF11">
        <property type="entry name" value="CYTOSOLIC CARBOXYPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18027">
        <property type="entry name" value="Pepdidase_M14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M14" evidence="4">
        <location>
            <begin position="117"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1743831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="806" mass="87861" checksum="72420C728E8286B2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGI2</accession>
    <name>A0AAD9DGI2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Dynein light chain roadblock</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_002974</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Cytoplasm</location>
            <location evidence="1 10">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the GAMAD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGI2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.30:FF:000011">
        <property type="entry name" value="Dynein light chain roadblock"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016561">
        <property type="entry name" value="DYNLRB1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004942">
        <property type="entry name" value="Roadblock/LAMTOR2_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10779">
        <property type="entry name" value="DYNEIN LIGHT CHAIN ROADBLOCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03259">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009998">
        <property type="entry name" value="DLC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00960">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103196">
        <property type="entry name" value="Roadblock/LC7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6 10" id="KW-0243">Dynein</keyword>
    <keyword evidence="5 10" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 10" id="KW-0505">Motor protein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Roadblock/LAMTOR2" evidence="11">
        <location>
            <begin position="15"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR009998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1746367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="112" mass="12538" checksum="8A1D95A57B4A52E6" modified="2024-05-29" version="1">MSNQETTANFTTAEMEETIARISSHKGVEGVMIMNREACRCHHSIDLDEDKAKTHSAALSELTAKASHIVGLLNRDDELTFLRIRSKQREIMVSPDKGFILVVLQNPNVSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGI9</accession>
    <name>A0AAD9DGI9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004326</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGI9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042193632" evidence="1">
        <location>
            <begin position="20"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="149" mass="16300" checksum="63EFE184C9CDE1AE" modified="2024-05-29" version="1">MKTSVASLLFATVATRTSAFAPASRNAFSRNMSANSVPLANGAMSFDRVCREWRCKYEGDKATSESLEAISKLVDEYLPEVKKASSDVTVNRLICGGCLDFKLMTTVPLDDFGPWEESGFAPEAEFLEKLKAIEGVSQVETQTITNMII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DH07</accession>
    <name>A0AAD9DH07_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATP-dependent Clp protease adaptor protein ClpS1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_004594</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DH07"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022935">
        <property type="entry name" value="ClpS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003769">
        <property type="entry name" value="ClpS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_bL12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33473">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ADAPTER PROTEIN CLPS1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33473:SF17">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ADAPTER PROTEIN CLPS1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02617">
        <property type="entry name" value="ClpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="ClpS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042208252" evidence="2">
        <location>
            <begin position="21"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Adaptor protein ClpS core" evidence="3">
        <location>
            <begin position="83"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1745303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="177" mass="19064" checksum="DBD702DCF321991C" modified="2024-05-29" version="1">MQMIQSLLFAVAMCLSQVAAFSPAANRPAVQITSRTFSTPTILRMSDSGGGGGGMEKAKDKKKGLSTIVIDKTDTQMEEEDTPEEMWRVVLHNDEVHTFNYVIRSLQKVMGTLDKKKAFDICTVTHGQGQATVDECWKAQAMKYCLGLQRQGLTASIAPSNKFEGGGNDAGGGPESG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHX6</accession>
    <name>A0AAD9DHX6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">VWA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_002855</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHX6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039891">
        <property type="entry name" value="VWA8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21610">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21610:SF9">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase dynein-related AAA" evidence="3">
        <location>
            <begin position="99"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase dynein-related AAA" evidence="3">
        <location>
            <begin position="338"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase dynein-related AAA" evidence="3">
        <location>
            <begin position="631"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="860"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="917"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="880"/>
            <end position="895"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1746248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1192" mass="132924" checksum="B4FFCE0F8FDFAB65" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIC4</accession>
    <name>A0AAD9DIC4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ACB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_000870</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIC4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1748931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="116" mass="13360" checksum="EB22C231A41D98E5" modified="2024-05-29" version="1">MRNDDRDRLIVSCFETVSDLIRNSKPTDEEKAYVTDSFRLKLYVGRAKYDAWVECESLCGGDRVAAMKNYLELASSVTQTGVGRQCRDIYDDAIKQIEQTQPISPTQKKSQVMWRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DK84</accession>
    <name>A0AAD9DK84_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">KRI1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_000362</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KRI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DK84"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018034">
        <property type="entry name" value="Kri1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024626">
        <property type="entry name" value="Kri1-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14490:SF5">
        <property type="entry name" value="PROTEIN KRI1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14490">
        <property type="entry name" value="ZINC FINGER, ZZ TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05178">
        <property type="entry name" value="Kri1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12936">
        <property type="entry name" value="Kri1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kri1-like C-terminal" evidence="3">
        <location>
            <begin position="478"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="80"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="290"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="407"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="535"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="308"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="407"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="422"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="549"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="578"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="601"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="639"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="650"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="662"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="695"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="745"/>
            <end position="762"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1748423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="828" mass="94463" checksum="48C6701A3CDF2AC3" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRK7</accession>
    <name>A0AAD8XRK7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_016990</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 5"/>
    <dbReference type="EMBL" id="JATAAI010000073">
        <property type="protein sequence ID" value="KAK1732323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRK7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000025">
        <property type="entry name" value="Peptidylprolyl isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050689">
        <property type="entry name" value="FKBP-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516:SF443">
        <property type="entry name" value="FK506-BINDING PROTEIN 59-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="7">
        <location>
            <begin position="20"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1732323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="129" mass="13597" checksum="BB3D05CF5CABA67C" modified="2024-05-29" version="1">MGVTKTTISAGDGSNFPTPGDKLTMHYHGTLASNGQKFDASKDRGRPFQFTIGIGQVIKGWDEGVMQMSLGEKAMLQITSDYGYGARGAGGVIPPNADLNFEVELLAINGKNAPQYAGESSSSSYCSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XT69</accession>
    <name>A0AAD8XT69_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Calmodulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_016369</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000055">
        <property type="protein sequence ID" value="KAK1733038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XT69"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042106938" description="Calmodulin" evidence="3">
        <location>
            <begin position="27"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="414"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="362"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1733038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="517" mass="55098" checksum="16960714FEC57685" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTJ2</accession>
    <name>A0AAD8XTJ2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016109</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000052">
        <property type="protein sequence ID" value="KAK1733252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTJ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="883"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1146"/>
            <end position="1197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="928"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1146"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1158"/>
            <end position="1181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1197" mass="130858" checksum="9BDD05F70AE1C5C3" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTU1</accession>
    <name>A0AAD8XTU1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fidgetin-like protein 1</fullName>
            <ecNumber evidence="6">3.6.4.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_015811</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000048">
        <property type="protein sequence ID" value="KAK1733523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTU1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050304">
        <property type="entry name" value="MT-severing_AAA_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074:SF17">
        <property type="entry name" value="FIDGETIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="922"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="566"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="456"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="70"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="487"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1733523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="962" mass="107010" checksum="FAEEB7EA6A557AC8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XU59</accession>
    <name>A0AAD8XU59_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UAS domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015823</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000048">
        <property type="protein sequence ID" value="KAK1733535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XU59"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02958">
        <property type="entry name" value="UAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006577">
        <property type="entry name" value="UAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050730">
        <property type="entry name" value="UBX_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322">
        <property type="entry name" value="FAS-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322:SF6">
        <property type="entry name" value="UBX DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13899">
        <property type="entry name" value="Thioredoxin_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00594">
        <property type="entry name" value="UAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UAS" evidence="2">
        <location>
            <begin position="102"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="358" mass="40826" checksum="793E3114E99AC382" modified="2024-05-29" version="1">MNENETKKPPAASRCVEPLLGRARPCGMAGAEVERGREYNMNENKTKKPPDASRRIPPADNTTQLHDCSHNGCSMMARSNGFCDDHHDTALMAWSPSNDGKQQPSILSNTFGPPIDLIYSGGFYNAKYDARTKQRWLLVNIQNKDVFACHNLNRDVWQNEGVQNLIQASFIFWQTLRTSVEGERYCQQYKVKGYPHISIINPFDESVRFRKEEWTQTKPLTAQTLEDIVSKFVNEDPIESKHQPIKSCITNGGNNVLIHRKREVLFHRKREGEEEHPDIQAAIHSSLQDGKSCVTTVRIPPRMATRSSMKKKTAAPTVSIIIPRRMATRSSTKEKMKNVSFLDDCTTEGITKRRKRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XU96</accession>
    <name>A0AAD8XU96_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Inositol-1-monophosphatase</fullName>
            <ecNumber evidence="8">3.1.3.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_015277</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>a myo-inositol phosphate + H2O = myo-inositol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:24056"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:84139"/>
            <dbReference type="EC" id="3.1.3.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 7 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="8">Polyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.25" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1734019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XU96"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008934">
        <property type="term" value="F:inositol monophosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006020">
        <property type="term" value="P:inositol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01639">
        <property type="entry name" value="IMPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.540.10:FF:000069">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033942">
        <property type="entry name" value="IMPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20854">
        <property type="entry name" value="INOSITOL MONOPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20854:SF4">
        <property type="entry name" value="INOSITOL-1-MONOPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041916795" description="Inositol-1-monophosphatase" evidence="9">
        <location>
            <begin position="27"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600760-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1734019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="341" mass="36353" checksum="022EE10EA0EE242F" modified="2024-05-29" version="1">MVTPNHSYPLLLLLLGSLAVVSVVDSFTTPKTYNFNLKSSRSKSTAMMTSAGNIELPSQETLDSLLSVAITASKQAGEIILGNAGGADVLKSKANSRDLLTLIDPLCEKTIRETVLASFPTHAFLGEEDVPPGKEASAAAIEAKLQQLNDADDNDNYLWIVDPIDGTSNFVHGMPLCMPSVAVAYKGEVVVGVIHDPHRMETFSAVRGRGAQMNGEPISVGQQSDIGDAIVAMGSPPAEESMKMSLAALPVLMPKVRTIRMIGSAALMLAWVANGRLTAYWEYDLSSWDVAAGSILIEEAGGSMTDLNDERWNLRTRKICGSNGGNVHKQILEALGEANVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUT7</accession>
    <name>A0AAD8XUT7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_015257</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1733999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUT7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1733999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="412" mass="46186" checksum="70AA89403B5295B9" modified="2024-05-29" version="1" fragment="single">MDVAIDRQRAMEGRDFDYYEERAQDVVLEDITSCEGNAEILQRLRRQDTSLKNLTISDDADADNYIVGEGDDFGWLGYFIGNSKYLHDLDVYSLGEGQNIEALIDGINRNRLIGSIHIRTDLGDVNFRNLTPFFRNSHRLAQLELNFEVGLECAQSIAFALGTSQCQSLESLRFQDCNLSDEGFAVIANALRTYSQLEELYLEKNNIGLMGCIALGDSMRGWGASNLTILDLDDNAIEDQGLEALAAGMTNTKLEELYLSRNLITGAGLRSMSEYFQSESCCLETLNLYRNVFGDEGAVALADGLMGNKSLTSLRFIPDESGITDVGWAAFSRLLCDPSSINSTYHSNHNIERIGGPEMLSTPLDITQYFELNVRPHPAIHKILKSHPDLEMEPFFQWKLKLLPVVINWFQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVN1</accession>
    <name>A0AAD8XVN1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVN1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="264"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="292"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="391"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="477"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="548" mass="58929" checksum="7A1F47300C07D01C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW27</accession>
    <name>A0AAD8XW27_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014532</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XW27"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041976067" description="Transmembrane protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="506" mass="56114" checksum="4DA1494F48575516" modified="2024-05-29" version="1">MKTILRTMLLFSIVFLVLVAVGASAFQTTASSNAKHQTTAPVLFSSKRDGDDGYTTKEKMKRRRRQRNLDFWGVDMHSKSDAAPQFPSTFEGVAEQAFEAIAGTICGLQRPDPNVASNAMHSSVLDYRPTHSPYASIKRWGNGDERPISKKDMEAPARIGIEIDGASFLLLKEHLQSDIKGTAEGRAMIIFSLELAQRLVASPWNGFEEASSGLRPCAVFYNTMDQALMASRELSRLKEEVRTNKDILDQIHISSLGQGSLPTHMEKKRKKQPTNGIVLVVKPTDYDIDSPIPNIGRPTVYADCLEKLQRILFQASASSLPAIVISPRLTELAPLVQPPTTHTYKTGPWGYEQSNYQRSATYGGIEPPVGPTSWLLRDLIPPVYVWIGCSLDIAGANTVRKRKLLAKPSLRSIAESYRNQQRIDKGEDHAGSVDDATEYSFYSRLAMTQSSMETGHAWNIFAVKENASNEDWQSSHQFIGSSMASRGRPSSGIMKDVFVEWISHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW75</accession>
    <name>A0AAD8XW75_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycosyltransferase (Family 2)</fullName>
            <ecNumber evidence="8">2.4.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_014518</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 92 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.-.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XW75"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008166">
        <property type="entry name" value="Glyco_transf_92"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21461">
        <property type="entry name" value="GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21461:SF69">
        <property type="entry name" value="GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01697">
        <property type="entry name" value="Glyco_transf_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1734645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="640" mass="72097" checksum="96CC0254B5020732" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWR7</accession>
    <name>A0AAD8XWR7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014464</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1735004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWR7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1735004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="99" mass="11175" checksum="36B70B97A9CCE52C" modified="2024-05-29" version="1">MPSPAADEAQITLAAEDLIQASRACYRIIFLLAAVRLGTTLIDDNIWSKLFDPNQPNLGWEDCVDLFDSTTWLVSGLSMWHCATLQERNKTIEKMKCKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXI1</accession>
    <name>A0AAD8XXI1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nuclear pore complex protein Nup85</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_013906</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Functions as a component of the nuclear pore complex (NPC).</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the nuclear pore complex (NPC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
            <location evidence="1 9">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the nucleoporin Nup85 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXI1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011502">
        <property type="entry name" value="Nucleoporin_Nup85"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13373">
        <property type="entry name" value="FROUNT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13373:SF21">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07575">
        <property type="entry name" value="Nucleopor_Nup85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 9" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7 9" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1735292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="546" mass="59146" checksum="2AE7AA1A1293BAAA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZP1</accession>
    <name>A0AAD8XZP1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 15">Pyruvate kinase</fullName>
            <ecNumber evidence="5 15">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">QTG54_012740</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>pyruvate + ATP = phosphoenolpyruvate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 15">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the pyruvate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="5 15"/>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZP1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.33.10:FF:000001">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.60:FF:000001">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="entry name" value="Pyruvate kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004491">
        <property type="entry name" value="PRK05826.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004978">
        <property type="entry name" value="PRK06354.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PYRUVATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="PK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12 15" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 15 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13 18" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15 18" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate kinase barrel" evidence="16">
        <location>
            <begin position="30"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate kinase C-terminal" evidence="17">
        <location>
            <begin position="394"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1736718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="509" mass="54773" checksum="181FC2621CD279AA" modified="2024-05-29" version="1">MQSQSASGPELRGSNITLDRVKSATDVTTRKTKIICTLGPACWEVSQLEQLIEAGMNVARFNFSHGDHEGHKACLDRLRQASKNKNKHVGVLLDTKGPEIRSGFFANDAKKINLAKGANITLTADYNFKGDSKKLACSYPQLATSVKPGQPILCADGSLVLTVLSCHPAEGEVICRIENDCGIGERKNMNLPGVIVELPTLTDKDIDDIVNWGIKNEVDYIAASFVRKASDVHQIREILGDMDGKIKIYCKIENQEGMENYSDILAATDGIMVARGDLGMEIPPEKVFLAQKMMIREANIAGKPVITATQMLESMITNPRPTRAECSDVANAVLDGTDCVMLSGETANGEHPVAAVSIMARTCVEAESAVNFDSLYQAVRNSTLKKYGTLSTSESIASSAVKTAIDINAKAIIVMSESGNTARQVAKFRPGMPVKVICTSEQVANQCYGTLKGCSAHTVENMDMEDAMVNEVMEELKASGKANAGDSVVIVHGTVAKSGATNTMKIEYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZZ8</accession>
    <name>A0AAD8XZZ8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Triacylglycerol lipase</fullName>
            <ecNumber evidence="6">3.1.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_013000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.3" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZZ8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021771">
        <property type="entry name" value="Triacylglycerol_lipase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF10">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11815">
        <property type="entry name" value="DUF3336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3 4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="5">
        <location>
            <begin position="232"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="4">
        <location>
            <begin position="263"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1736400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="727" mass="82690" checksum="95FE9123C878819C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y046</accession>
    <name>A0AAD8Y046_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012622</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y046"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="127" mass="14725" checksum="DE78C138C4FA0CDC" modified="2024-05-29" version="1">MTDECNDLSPYEMARLERIKRNESRLRELGLVKPKPKPKPKPKPAAIVRKRKQPSSAPTRSSRRLRELKEGKEQLVEEDDDSTNNVDAADTTLIDQITVDYERMPDEPERLDDEEFQVYVSLLATRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0K1</accession>
    <name>A0AAD8Y0K1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylglyoxal synthase</fullName>
            <ecNumber evidence="2">4.2.3.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012252</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.3" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0K1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008929">
        <property type="term" value="F:methylglyoxal synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019242">
        <property type="term" value="P:methylglyoxal biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="entry name" value="Methylglyoxal synthase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004363">
        <property type="entry name" value="Methylgl_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018148">
        <property type="entry name" value="Methylglyoxal_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003559">
        <property type="entry name" value="PRK05234.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30492">
        <property type="entry name" value="METHYLGLYOXAL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30492:SF0">
        <property type="entry name" value="METHYLGLYOXAL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="Methylglyoxal synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01335">
        <property type="entry name" value="METHYLGLYOXAL_SYNTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="225"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="358" mass="38667" checksum="3B52831C34EF2B9F" modified="2024-05-29" version="1">MSRRESFAVQLDNHRRTSQRRGSTYAQRLSLADAVGTATDEVTAPFTSTFAPGEMRQLALVAHNHMKPAMKQFIETYSEILKKFRITGTQTTMKMCKSMWGEDDPSIHYGLTCTSGPLGGDAQIAALMCVEDLGGIIFFVDPLSAHPHQADIDSLLRLANCGNIIVCPNPASASSMMHTLRCALLKGDSARGMIPSFFETLESPAVEEYKHQQAVALANVIKGNSPSAPAPQAAEPPKEVGKSVSFGTEKSVSFGEPAPVEEEKKKKEVAAISQTTIDRALMGQSMMFSDERLQALLAVESDDDSDDDEEEGSSVADAPTAKVSKGLFGIKTSSTKKSRGRMGLKKLGKSVRNMMISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0X2</accession>
    <name>A0AAD8Y0X2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012432</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0X2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1736987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="171" mass="18605" checksum="19C52B5354B2F45A" modified="2024-05-29" version="1">MSVAQLTKASFTISRLGLAEYMPKEALDYLEYLKGPLTTGRAGMITCEVSTGQFSKTRAAIKAWRPYKMTEGWHYLTFTDCNDDGWVGFGQDETVDVDIKYKGKLGYASPSQSSRGGSKFMSMVSTSYNIGNVGEQATNACCSPEPGVARDCSAVHAMIVSFDLSSVEKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1I5</accession>
    <name>A0AAD8Y1I5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012043</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1I5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042179783" evidence="2">
        <location>
            <begin position="24"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="438"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="466"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="643" mass="68178" checksum="E38963025757F63D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y221</accession>
    <name>A0AAD8Y221_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclin-H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y221"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="1">
        <location>
            <begin position="123"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="401" mass="44917" checksum="1BCD694C793A55ED" modified="2024-05-29" version="1">MLYEESSQAFKWQLSSLVELNSLRERANRRARDVLSREDAAPLEVYGFADTRGDRPKPTTDDQVVQLMSEDDLNYGPTKTSKARGSNALLTPSDETLLLSFYCSKIPLLIGPHATLPRCKRDAKVAATASLLFRRFYLSNSVMIHDPKTMLAAAAFLAAKVEDCMLDVRYLEMGTKEMNAPVPLTDILDAEIRLMKGIDFDLLVFSPYKTIVPIVEDLRTFLKSERGKGLVKWKEGEERQLEREDLRPVHDMAMKIVDDVIVSDIPLMYAPGEVGTAALVVANEDVCNNQRKGNDEDGGGVEGDKVESPEIDIVGYVRSRFEDTDESGVVVDTAAIDALVERVSRLAQLIRELREGKHGCGNYNADMNELKGVNKKLKKCRAWGSSDKKDKKKRKRKQAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y359</accession>
    <name>A0AAD8Y359_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6824 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010844</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y359"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049227">
        <property type="entry name" value="DUF6824"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20710">
        <property type="entry name" value="DUF6824"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6824" evidence="1">
        <location>
            <begin position="2"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="118" mass="13415" checksum="966C76C744A9BB68" modified="2024-05-29" version="1">MKAEYLSDTTRKNQKTQIAANIVWTIRNSKLPGRFLKQDPETNMWYEIGDKAAFRKTGQALRENSADFLRSREKKVAASHETGLAVSLASYHYCFPPQQTYMKPQLSNLSGIDAVHAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y367</accession>
    <name>A0AAD8Y367_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Adenosine deaminase</fullName>
            <ecNumber evidence="9">3.5.4.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_010859</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; purine nucleoside salvage.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.4" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y367"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000034">
        <property type="term" value="F:adenine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006146">
        <property type="term" value="P:adenine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043103">
        <property type="term" value="P:hypoxanthine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01430">
        <property type="entry name" value="aden_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43114">
        <property type="entry name" value="ADENINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43114:SF6">
        <property type="entry name" value="ADENINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Adenosine deaminase" evidence="8">
        <location>
            <begin position="36"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1738190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="281" mass="32239" checksum="5C693AA872C173E5" modified="2024-05-29" version="1">MCRGRQQRQQKQKTANYSDVNSQSSAMLKRFVTTMPKVELHVHLEGTLEPELVLTLAERNNIDLSSYFKDVNDLRSKYESIKCLNSFLQVYHRCASVLRTERDFYDATMAYLSRAKKDNVVYAELFFDPQCHKQTGVSFETMADGILAAVDDANHQLDIKCKLIPCFMRHLSEASAMSMWSEIFKYFQQHPKARDKIIGIGLDSDEQDNPPSKFHGVFWKIRHASKSVVGDMHIVAHAGEEGPSNYISQALNLLRSERIDHGVQCLSDDKLVQRLRDEHIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y393</accession>
    <name>A0AAD8Y393_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin), chloroplastic</fullName>
            <ecNumber evidence="11">1.17.7.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">QTG54_011062</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + 2 reduced [2Fe-2S]-[ferredoxin] + H(+)</text>
            <dbReference type="Rhea" id="RHEA:26119"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:58483"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="EC" id="1.17.7.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="9">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 5/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the IspG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.7.1" evidence="11"/>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y393"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046429">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity (ferredoxin)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.20:FF:000005">
        <property type="entry name" value="4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.413.10:FF:000006">
        <property type="entry name" value="4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="entry name" value="Dihydropteroate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="entry name" value="Sulfite Reductase Hemoprotein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00159">
        <property type="entry name" value="IspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017178">
        <property type="entry name" value="IspG_atypical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004588">
        <property type="entry name" value="IspG_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058579">
        <property type="entry name" value="IspG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058578">
        <property type="entry name" value="IspG_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00612">
        <property type="entry name" value="ispG_gcpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30454">
        <property type="entry name" value="4-HYDROXY-3-METHYLBUT-2-EN-1-YL DIPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30454:SF0">
        <property type="entry name" value="4-HYDROXY-3-METHYLBUT-2-EN-1-YL DIPHOSPHATE SYNTHASE (FERREDOXIN), CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04551">
        <property type="entry name" value="GcpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26540">
        <property type="entry name" value="GcpE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037336">
        <property type="entry name" value="IspG_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="Nitrite and sulphite reductase 4Fe-4S domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041901994" description="4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin), chloroplastic" evidence="14">
        <location>
            <begin position="22"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="domain" description="IspG TIM-barrel" evidence="15">
        <location>
            <begin position="79"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="IspG C-terminal" evidence="16">
        <location>
            <begin position="641"/>
            <end position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00051119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00060620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00061554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00067018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00072132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00083306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF26540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1738393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="750" mass="82013" checksum="564ED1A617850508" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3C5</accession>
    <name>A0AAD8Y3C5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010931</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3C5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051218">
        <property type="entry name" value="Sec_MonoDiacylglyc_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856:SF11">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="Fungal lipase-type" evidence="2">
        <location>
            <begin position="23"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="264" mass="30157" checksum="4496C08519939627" modified="2024-05-29" version="1">MSLISEIREKVVIIGQELANGTNAGYHLSVVGHSRGGGYATVLGYYLASDMYLEVASAVRVFTFASSPVGCADFQKGFKHLEEEGRLVHARFANSNDLFTSLPLRGYSEENKSKVKYHHVGMQVRLHKANEAGRRRIKQSLDVSYDAKEPLLMEIARVARNVLSLIKALICFVYTKNYCISQYHLRMHFAREYRLALGDGALRFDRKRKCLKSLNEYYVMKCRRVHNYTGFKEKPALLPTWAVIMLVTSILYVQIDIFLKFAGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3S9</accession>
    <name>A0AAD8Y3S9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MAP3K-like serine/threonine kinase</fullName>
            <ecNumber evidence="7">2.7.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_010435</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3S9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF288">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="200"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="70"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="79"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="122"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1739119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="598" mass="66182" checksum="3B3EEACEC39A7AE9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y425</accession>
    <name>A0AAD8Y425_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010129</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y425"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042085642" evidence="2">
        <location>
            <begin position="29"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="273" mass="30156" checksum="D48CCB8236BFAB63" modified="2024-05-29" version="1">MKSHLHLLVSANLMLALLRLSTLPGALSAEAEAEESKLQGAVAVNSLEDQISNFYFSEEEDAKIKENIERSRYGRMSGKSGKSIPSCTKRLLNDCYHVGRQVRRGYSLPSSVSVRSRGDSGFFREICRDVCDVRIPSEKYRGSSSKSNTSSDIIVRKSDKSDSDFSNVEGASEMEPSKAWDDDYDEDMMDIDTFGGNEDGDGDLLASIITVKGDSAGMTSIRAARLANRLIPLRCRERATVHLSSTVLFDAALHVGVQKFWLHSRIIPHCTPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4Q1</accession>
    <name>A0AAD8Y4Q1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4Q1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43096">
        <property type="entry name" value="DNAJ HOMOLOG 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43096:SF52">
        <property type="entry name" value="DNAJ HOMOLOG 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="3"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="188" mass="21142" checksum="3B98306E69A7DB78" modified="2024-05-29" version="1">MPTHYDTLGVSKSASTDEIKKAYRKLCMQYHPDVASSSSSKSTAQSKNADKFKRISEAYSILGNENKRRRYNFDISESGIQELRKKAAKARGTAGGGGNSFAATLPRNVLIGGILGIAGVTIIRSIMPEKENDDTHHEHTGKKRLVEAWLNPKTKRWEKPRPWDEEYQRLQPVLQFVPRDQVDDGGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y579</accession>
    <name>A0AAD8Y579_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sorting nexin 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010191</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y579"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555:SF170">
        <property type="entry name" value="FI18122P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="2">
        <location>
            <begin position="22"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="182"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="387" mass="43125" checksum="705D2488D705A6C8" modified="2024-05-29" version="1">MMSTIDPNAELFDDGRGGGGGGTLHLSVTDPQQIGEGRNAHTFYRIDVRPNQYADTIASVRRRYSDFRWLFQRLHEERPGAIIPIIPHTKAFQIEKRLSEELIEERRVSLFEQAKKDHPETEGFISEDGTTSSAKEKAKVARGVDLEETPDAAQVDEVEQYLSALETHTYDPDTTTPDDNDSSSSSNNSNAKSKNPSLKTISNIFASLSAINKVKYDDNYAKVSKPIIDIQDNIKAARLALKRRKDHAITYNTFLQQIKNRQAALEKLNHKNATSPQATTENQIVSTQQLLDESNKSSKVALAALEKVTQRVFREMDRFKHSVDAQLRLLYVNHARVQVDYSRQLDVEWNKLLPNGNAGSGGAVNGRVGGSGADDGVLSKEAEMLMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y650</accession>
    <name>A0AAD8Y650_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009328</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y650"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="298"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="861" mass="91654" checksum="18828652847FCBD3" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y685</accession>
    <name>A0AAD8Y685_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="1">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_008594</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y685"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049163">
        <property type="entry name" value="Pif1-like_2B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492:SF57">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21530">
        <property type="entry name" value="Pif1_2B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 5" id="KW-0347">Helicase</keyword>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="3">
        <location>
            <begin position="34"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="3">
        <location>
            <begin position="104"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="DNA helicase Pif1-like 2B" evidence="4">
        <location>
            <begin position="316"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF21530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1740499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="462" mass="52503" checksum="A8C8A216EBFA48DC" modified="2024-05-29" version="1">MPEENEANDNPNEVPPEEVDHNAEEYVASNQDLLTDEQQYVCDRIKQSIESNQPGLFRLDSPGGTGKTFTSNYLLASVRMTGHIAIATALSGIAATLLTQLQSIDAEIIRQAELIIIDEVSMMSFKLLDVLDRLLQELMENNETMGGKKVLLMYDFRQLLPVVPGRGRADVVSETVLNSSIWRQFEELSLTNNMRVQRMIDEYPEREAELRQHEQWLLDIGTGEAQTAYDNIIEIPNRMVCTTQHELEEKVYDNFKDNYNDTTYLRNRAIMSTTNNVIQQCNFDMINQIPGELVVSTSIDKCVEDNDTTMYDEAVLNKVNVSGIPPHRLALKVGACIILIKNLNVRQQHCNGTRYIIQSMTNRLIAAKRLTDDELILIPRIPMVSQDSNFPVPFKRLQFPVLGAYYLTINRAQGQTLHKSGLYLERSVFTHGAFYVSMSRGEHHGENISMQIKRNSLILTSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6G8</accession>
    <name>A0AAD8Y6G8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008940</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1739990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6G8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1739990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="65" mass="6796" checksum="EB471C80E6050BBB" modified="2024-05-29" version="1">MKHFIVSANMGHNKSLDSLKNGFMAGVVSKDEFAAALRGHQAAIDATKSPQRDVASAALKKAAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7K1</accession>
    <name>A0AAD8Y7K1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Reverse transcriptase Ty1/copia-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008224</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7K1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09272">
        <property type="entry name" value="RNase_HI_RT_Ty1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="782" mass="87584" checksum="D985E30947C89316" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8T4</accession>
    <name>A0AAD8Y8T4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">MIP/aquaporin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_008376</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8T4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034294">
        <property type="entry name" value="Aquaporin_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139">
        <property type="entry name" value="AQUAPORIN TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139:SF199">
        <property type="entry name" value="MIP17260P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="256"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1741124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="281" mass="29580" checksum="F6542D41E2BDD2A8" modified="2024-05-29" version="1">MDGEGAIFDAGALTAISIAFGLTISVLAYGIGHISGGHINPAVTLSFMVLRLKSITAGLLYMLAQFAGATLGAFILWGCTASLTEHCDDERDSDGNLPGDINGVCSSSAKADGSGYGPPFSLGVNMVAPRVSTGSAFLIEMMGTFLLVFTVLQVAVHNKSTAGNVAPIAIGWAVLVAHLVLIPFTGCGINPARSFGPMIVDTIGGMDVWVRGCWVFYTAPFIGSTVAALTYKFIFCEEEDVKDAVEEAAMKKNDDLEKVNRPEIDDLELQPNGTGETEDME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9H2</accession>
    <name>A0AAD8Y9H2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_007580</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9H2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23767">
        <property type="entry name" value="IQCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052267">
        <property type="entry name" value="N-DRC_Component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14690">
        <property type="entry name" value="IQ MOTIF CONTAINING WITH AAA DOMAIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14690:SF0">
        <property type="entry name" value="IQ MOTIF CONTAINING WITH AAA DOMAIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase AAA-type core" evidence="3">
        <location>
            <begin position="514"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="141"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="398"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="232"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="404"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1742007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="765" mass="85845" checksum="A908D86E958D67DE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9S1</accession>
    <name>A0AAD8Y9S1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PUB domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_007213</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9S1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012506">
        <property type="term" value="C:vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09212">
        <property type="entry name" value="PUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036339">
        <property type="entry name" value="PUB-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018997">
        <property type="entry name" value="PUB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46467">
        <property type="entry name" value="TETHER CONTAINING UBX DOMAIN FOR GLUT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46467:SF1">
        <property type="entry name" value="TETHER CONTAINING UBX DOMAIN FOR GLUT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09409">
        <property type="entry name" value="PUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00580">
        <property type="entry name" value="PUG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143503">
        <property type="entry name" value="PUG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBX" evidence="3">
        <location>
            <begin position="491"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="322"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="424"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="613"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="391"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="332"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="428"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="443"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1741640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="666" mass="71119" checksum="BF34ED623642DC40" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAB3</accession>
    <name>A0AAD8YAB3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Retinol dehydrogenase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006977</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAB3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF148">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1742412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="187" mass="20409" checksum="31382B0C1790BFD6" modified="2024-05-29" version="1" fragment="single">IAIITGSNTGVGFETAQGLAQRGYHVILACRNRQKGLDAREEDESKVVGKASFLQPLDLASFASIRSFCNSFSEKYDSLNILVNNAGINSQGDVTEDGLEMCFQSNFVGHFLLTKLLIPSLLNAENTYKNNKYKDEAGRIVNLSSVTHHFAPSNERIHPNDGSSDLSENNGIHDKTFGLGLNAWSIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAT9</accession>
    <name>A0AAD8YAT9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">pyruvate, water dikinase</fullName>
            <ecNumber evidence="5">2.7.9.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Pyruvate, water dikinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">QTG54_006730</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>pyruvate + ATP + H2O = phosphoenolpyruvate + AMP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:11364"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.9.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.9.2" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAT9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008986">
        <property type="term" value="F:pyruvate, water dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006319">
        <property type="entry name" value="PEP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43030">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43030:SF1">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042146067" description="pyruvate, water dikinase" evidence="14">
        <location>
            <begin position="20"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate phosphate dikinase AMP/ATP-binding" evidence="15">
        <location>
            <begin position="67"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1742165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="129" mass="14273" checksum="E7DDD0E991ABD79F" modified="2024-05-29" version="1">MMLLKTAILLSWAANECTAFVPSTSILVPRRDLFQPHLSNHSEVSTKNEVKVKHCIPLQEIGLDDLPRVGGKTASLGEMIQNLAPLDVSVPGGFGVSSSAYDAVLDRFKLRERLDLLLLLKDVDVKMWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YB35</accession>
    <name>A0AAD8YB35_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fidgetin-like protein</fullName>
            <ecNumber evidence="6">3.6.4.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_005817</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YB35"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000022">
        <property type="entry name" value="Fidgetin like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000093">
        <property type="entry name" value="Fidgetin-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050304">
        <property type="entry name" value="MT-severing_AAA_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015415">
        <property type="entry name" value="Spast_Vps4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074:SF17">
        <property type="entry name" value="FIDGETIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09336">
        <property type="entry name" value="Vps4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="509"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="162"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="302"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="398"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="746"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="173"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="211"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="244"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="302"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="375"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="418"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="753"/>
            <end position="768"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1743196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="768" mass="85587" checksum="26F47CD4140F3682" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YB68</accession>
    <name>A0AAD8YB68_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ubiquitin-conjugating enzyme E2</fullName>
            <ecNumber evidence="4">2.3.2.23</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_005850</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YB68"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23799">
        <property type="entry name" value="UBCc_UBE2J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000086">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 J1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="357"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="UBC core" evidence="3">
        <location>
            <begin position="5"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="312"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1743229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="391" mass="42341" checksum="CE71BC0A6F2854D5" modified="2024-05-29" version="1">MSKSPSLRRIKADIRELSIDPSDQYYAAPLETDMFEWHFTIRGPADSEFAGGVYHGKILLPPEYPFKPPNIVFCTPSGRFETNVKVCLSFSAHHPELWQPAWGIRLILEAIISFLPTPADGAIGALDWTKEERAKLAKESVKFHCPVCCAVGQSCAELLPDIPPAADEKSEDNGNNDKKKKTSKFQEEIEKLKMLQGMHHAKEEEEDDDVADSGGESKEEAKETEQGGSTSIDETSQLLPSVTEDGADTCASESQETKPKPIEEANDNAKPAPLPDQNPPDQSSSEPSDMNPALEQSTPDNATESPTTTNVTSAAGAGAETSAGNQTSDAVAPPAINNQGNIPAASPQHSILVTEPFLNGMILAFSVTVMYLLTQAYYLLEELNVLNTVNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YC92</accession>
    <name>A0AAD8YC92_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sepiapterin reductase</fullName>
            <ecNumber evidence="5">1.1.1.153</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_005393</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.153" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YC92"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004757">
        <property type="term" value="F:sepiapterin reductase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051721">
        <property type="entry name" value="Biopterin_syn/organic_redct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44085">
        <property type="entry name" value="SEPIAPTERIN REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44085:SF2">
        <property type="entry name" value="SEPIAPTERIN REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1743796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="215" mass="23513" checksum="1622E0ED209A6667" modified="2024-05-29" version="1">MDLANIDNLPQNVEKILEPLANENYNSCLLINNAGSLGPLGKVTSICDEESPTEALRRWKDTIDFNVTSSLWLTSQFAKATSHVPHVRVINISSLCAIDPFPTMSLYCAGKAARDMFHAVLAKEHTQQTDGEGTTPSTSNPAQFKVLNYAPGACSTEMTDILADSADLDGGLQQFFSTSRDKKQLVRPDDTAAKLVGLLMKDEFESGSHVDYWDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCI5</accession>
    <name>A0AAD8YCI5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005239</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCI5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041968364" evidence="2">
        <location>
            <begin position="16"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="152" mass="16596" checksum="20AD02614E014B2F" modified="2024-05-29" version="1">MRVLLFALSASSVAAFAPSAVVRRTLNQSTSLNVDLEYGLKNGYVPASAGDGGQGEFGAQSPNDWRYPEPPPSVKPHTVVPLMVEKSLGSLRPSPLSVLTWRRQMRLLRLSPRMLPHSRLRNSAPPAHTNSPPLRPPLKNLLASLDTQNSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCY5</accession>
    <name>A0AAD8YCY5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nucleoside-diphosphate kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004704</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCY5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="entry name" value="Nucleoside diphosphate kinase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="Nucleoside diphosphate kinase, NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="209" mass="22773" checksum="B75D8AA244E6BA7A" modified="2024-05-29" version="1">MQACEKFGCNAAELDAAWQEAKVVKFGGGFYCGLVSVKDQSPLYVFNAFFMVMRSKFVGDGVSIHCYEVQWEPTKLSWENFRGQLLGPTDPKECPEGSIRRTILDQYESLGIKECPNKGDNGVHASASPFEGLAEKCNWLGASVDTDGFAKALLDAGLSKKTIAEWSVDPRVTQPGGDKGSVFDALEDMDVEECLAKLVELNGLNADTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD02</accession>
    <name>A0AAD8YD02_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutaredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_005935</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD02"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015038">
        <property type="term" value="F:glutathione disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03419">
        <property type="entry name" value="GRX_GRXh_1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011767">
        <property type="entry name" value="GLR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014025">
        <property type="entry name" value="Glutaredoxin_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694">
        <property type="entry name" value="GLUTAREDOXIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694:SF18">
        <property type="entry name" value="GLUTAREDOXIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00160">
        <property type="entry name" value="GLUTAREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00195">
        <property type="entry name" value="GLUTAREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="3">
        <location>
            <begin position="121"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1743314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="213" mass="22530" checksum="23AC49E50A66CFE5" modified="2024-05-29" version="1">MAGTRNPTDANTMRKFIATLQLQRTKHNFTTPLITMKINTLTVVSSLVVLQNATAFAVPPLGQNVVARSSTTTALAMGNPIDGLFAFLKEGKVGLVKSLAGDYDAAAVQSKMDKLISDNNVLMFSFTTCPFCIKAKETLDEKGAKYTVVELDQVSDGKAIRAVMGESLGRTSVPAIWIKGTFIGGCNDGPLGGINTLNSNNQLDGMLKAAGAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD32</accession>
    <name>A0AAD8YD32_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Coproporphyrinogen III oxidase</fullName>
            <ecNumber evidence="3">1.3.3.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004779</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.3" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD32"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1500.10">
        <property type="entry name" value="Coproporphyrinogen III oxidase, aerobic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001260">
        <property type="entry name" value="Coprogen_oxidase_aer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036406">
        <property type="entry name" value="Coprogen_oxidase_aer_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755">
        <property type="entry name" value="COPROPORPHYRINOGEN III OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755:SF3">
        <property type="entry name" value="COPROPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01218">
        <property type="entry name" value="Coprogen_oxidas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000166">
        <property type="entry name" value="Coproporphyri_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00073">
        <property type="entry name" value="COPRGNOXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102886">
        <property type="entry name" value="Coproporphyrinogen III oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041909881" evidence="2">
        <location>
            <begin position="27"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="380" mass="42111" checksum="27C6E87C3C38CF90" modified="2024-05-29" version="1">MMFLSLPKLSSVAICFLVAATTKVDAFAAPKSMPVSKAVGGSINDASSTPQDIFEEFTKFLINHQTDMISKIEQADGSENAFSRDGWGAFANDNDSSDEQQTKSGGITRVIQGGNVVEKGACSLTIIRNGVLTADRAATIQGRQQQQEGDLVVQEGDIYSAAALSVVLHTRNPFVPTFRSDVRIFLVKSASDDSAVAWFGGGSDLTPYYLIDEDISKFHKDLKQMCDSHFPEGNEYNLSHAQMKQFCDEYFYLPARSEHRGTGGIFFDDLSATKATLSFVEDVATGWMPSWLPIVEKNGSKEFTEEQKHWQCLRRGRYLEFNLLYDRGVKFGLANANPRVEGVMVSAPPKIAFDYNHVPAEGSEEERLLKILKEPKDWTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDI4</accession>
    <name>A0AAD8YDI4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004730</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDI4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="50"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="160" mass="18333" checksum="A1827101EFA53283" modified="2024-05-29" version="1">MGNRSSTPSSEEEGSSSGMYLTPELQGKINTDFEEKIIQTQWNSYRKGHIERYQQREAQNAQRHHELQQKQQQLNQQAKLVHDELDRMVDGAKSKLSDIEVALEYDMKRLSEKFQDSEVSGGEKCVDVRAELSRCYNTLDSGECQVFAKKLEKCVTEALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDQ3</accession>
    <name>A0AAD8YDQ3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_004835</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 5"/>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDQ3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000006">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044609">
        <property type="entry name" value="FKBP2/11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45779">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45779:SF7">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042196149" description="peptidylprolyl isomerase" evidence="6">
        <location>
            <begin position="20"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="7">
        <location>
            <begin position="71"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1744302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="178" mass="19616" checksum="F17BDFE91D250EBA" modified="2024-05-29" version="1">MKIAIALLLALAAIDSLSALSWRRKKQKKRAKEGWRRTKKGWERLNLPPDSKLQVGVTYRPKHCSAKSQKGDFISIHYNGTLFTNGNVFDSSILREYPFVFQLGKRSTHDGFEKGLLGMCVGEKRKLVVASGMAYGEVGGFGSEGAAKIKPNATLVYGVELLEILSEEAAAPDMVWGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YE56</accession>
    <name>A0AAD8YE56_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YE56"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="267"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="209"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="331"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="819" mass="90554" checksum="0DA7C344993F73E3" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFC8</accession>
    <name>A0AAD8YFC8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HAD superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004589</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFC8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01427">
        <property type="entry name" value="HAD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43885">
        <property type="entry name" value="HALOACID DEHALOGENASE-LIKE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43885:SF1">
        <property type="entry name" value="SUPERFAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G13290)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042090016" evidence="1">
        <location>
            <begin position="19"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="346" mass="37640" checksum="6377D4B99B891C49" modified="2024-05-29" version="1">MFLSPAAAVLLLLPTVLCFTSSPTSRNSVGNTVGLDNYSVNENASSTSSLIPELNDASRSISSNEQLLPSSPFGVIFDMDGTLIKHSINFAEMRQRIYEVVDADPIGKDLEKDCVLEMPQRLTEEGQRKCHEVFVDIEQRAVDNMQLQDGGAELVQFLIESGLKTAVLTRNMEKNVAHMMELYKNEMSINDDVTIFEPIVARNTKANPDDDEPLKSKPNPDGILHICKLWGCEPSEVIFVGDSANDDMSAANRAGCGGAVLLQPGGCQLDTDSGYAVGDTEAEIMERTPSLCVESLSDLKLCIESVLDEQEKNDVVQSEVSGEEDNYVYSSDSFSVTIPSIGVKGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFK9</accession>
    <name>A0AAD8YFK9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Calmodulin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_004254</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFK9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000003">
        <property type="entry name" value="Calmodulin A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050145">
        <property type="entry name" value="Centrin_CML-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23050">
        <property type="entry name" value="CALCIUM BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042083401" evidence="4">
        <location>
            <begin position="20"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="5">
        <location>
            <begin position="322"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="510"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="546"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="643"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="689"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="729"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="304"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="463"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="468"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="478"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1744963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="772" mass="85536" checksum="9309ECA5D7ACE41E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGA3</accession>
    <name>A0AAD8YGA3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004198</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGA3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="352" mass="39338" checksum="C4851AF6BF681E98" modified="2024-05-29" version="1">MDANRAGESSLPAAGISSVNVSFASPQSSIVSSLSATRVVNILIQNGFSSSSLLVDGDGNLDLTRLKLKQLKAVSKSLNTAEEDFNMPKSGATKIEWVNAIADFFRLSLDNGVRTSNSSNHNLGEAIPVNPNPRIESPPEKFGDDLETDQAFKAACGRVDDKTLWVVHLLAGYSHAEKITAQPYAFTSEKLVTQLISAPTSRFIQFLGEYVVHHCVNIWHTRKVNLVVFFICGEINEGYAWNQMFYNLGSFVRRHGKRTAASLLRRKQFAKCKDALDISQATKLAMEWALDIVRNINNRVSKYVFHGGKSLLHCVLENTQFEYIDRKETAFLIAYTLYNNLVLMRNLQNRNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGC7</accession>
    <name>A0AAD8YGC7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_003337</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGC7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="206"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1745413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="271" mass="30966" checksum="9F36CE7DB53F799D" modified="2024-05-29" version="1">MPSRKRAQGKARMKAKAMAKTKTAVAEAATNQQQELSSLMQQIYMCNHGHVPWQVDICAKFASELLNEYNATINRGDSPSPSPRTHTIKSLQAMNSKEEYSEVWNDAGKMKLLVAYFLSLGTKHATEENMWAARVYAHYACFFEEYIASELNNTQASMNRAKMVELLCASDDHTLISYLKHRIPCTCLNEMYKQVKSTKKMGLCFNEHCSHPDRMVDRDTMLNCTRCRSANYCSRECQVADWTRHKKMLCDEVAKAIASFNFKQNSKLSQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGX9</accession>
    <name>A0AAD8YGX9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cleavage stimulation factor subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_002938</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGX9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025742">
        <property type="entry name" value="CSTF2_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45735">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45735:SF2">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14327">
        <property type="entry name" value="CSTF2_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="60"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="74"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1746331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="264" mass="28327" checksum="48D9F6F65FFE43FC" modified="2024-05-29" version="1">MVSDQETGKPRGFAFIEFEDPQAALSAIRNMNEYEINGRKIRVNFSNSSHLETLAGQMGMDLSNVTGPKKDDNTTNQAQGGDGTQSSAEVAGSRAVASALKSMNKGEMYDVIAKLKEISDSNPEEARKILTQHPQLPEAILYCMSELDMIKTPVATSVLVCPFLLLELHHLSPPIRGHVQLLPNQCNYPIHEHDPPILVLPPGIPVPRGGSTQLSSPSYICCATTVHAASANATTASWSGWVRSQFGAASDAVDTSSDLAVASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHD3</accession>
    <name>A0AAD8YHD3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="5">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">QTG54_004507</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 23">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the pex2/pex10/pex12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHD3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16527">
        <property type="entry name" value="RING-HC_PEX10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025654">
        <property type="entry name" value="PEX2/10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23350">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23350:SF0">
        <property type="entry name" value="PEROXISOME BIOGENESIS FACTOR 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="7" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="14" id="KW-0653">Protein transport</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <keyword evidence="12" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <keyword evidence="11 18" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="20">
        <location>
            <begin position="502"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="227"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="270"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="477"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="227"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="272"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="292"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAK1745216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="557" mass="62346" checksum="0F078010EBD1F331" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YI67</accession>
    <name>A0AAD8YI67_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Calmodulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_002353</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YI67"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042239237" description="Calmodulin" evidence="3">
        <location>
            <begin position="20"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="235"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1747009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="305" mass="32852" checksum="0FD9261B16A9BCBC" modified="2024-05-29" version="1">MMNYLTFLLALTIFGGADAKNLRVSNAASKSSSEDIPVISSSRRKLQSSSEDIPTISSSRKLQSSSSEDIPTISSSRMLLTQAEIDSCYAIMDSTAVDDAINKDGYVEFLNLLAFGYLTENGITSFDDLSQSLKFAWNTLTCQCVQMGGADDCCAAGRANLFVEGADGEPVSEEQTNFLNDICSTAMTTLGSEGWENPPPGEMPKPTDDDTEEIEQELPAQPTNPAPETLTPGQIVGMSVGIPLLFILLLLGTLYFCRDKEYKPEEGEEEDDELADLDKEVMNDEDSAVGTVLTAEASTVVGSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2024-10-02" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIW7</accession>
    <name>A0AAD8YIW7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="1">
        <location>
            <begin position="56"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="1">
        <location>
            <begin position="825"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="1">
        <location>
            <begin position="1220"/>
            <end position="1365"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1375" mass="154108" checksum="F18B718CBCFB17BA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJN9</accession>
    <name>A0AAD8YJN9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phospholipase B-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJN9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042148848" description="Phospholipase B-like" evidence="1">
        <location>
            <begin position="17"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="308" mass="35048" checksum="38A338AF299FEB33" modified="2024-05-29" version="1">MTIDALLLILIVSATAVLFVDPFATSSTPADDELFFPPLADSSDISYFFGNYDLDGLHWALTNIFARSARNPNVSKELPQELVARGGGVTYTSEYKLKHDLAQAQYLLKYFKSKDPERAVYFESKVIPIYEKVLANIPPLDKLEKTKGLYAFTKEDYSLGIADVYNKGLFMTTADELDPNWRQHELLNEQLDFDAIQKEWFGDNAAGYSNEEMSTAASSPIPGVVVIDNLLDQRTLSLIRELLLKNTWWYQTKTPLEFGKYVGSYIDDGMHDPVLLELAKELHTKMPRIMNGHHLKYMWAYKYDSEVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJS1</accession>
    <name>A0AAD8YJS1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_001842</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJS1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02980">
        <property type="entry name" value="TRX_Fd_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47682">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT (TPR)-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47682:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT (TPR)-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="321" mass="34129" checksum="435311EBBE3C6611" modified="2024-05-29" version="1">MIKLSSSSAYCAAAAALLLYSVAGLLVNAFVVATIPSASSSSHIVLNAKVIRVCQSPGCRDDGAQSTLDSLTALAAPGCQVMKGGCVSGCGAGPVVEILPDGEDVMTISSIKRKKVKGDALISLLDELSDEETDISSSMRQRLIMGYEQALEAKAAYEAKDYQSAIQSYEDAIQIARNPAMALEEARASIGGDNYDSVKGVNWLVDSFRNSCRARLAMKDIDGARRDAFAATVFSQNTDADALMCLAEVCQASKDTMGELQATKAAIAQYQRLEDEYSKPMPGKDAVARAEAAKIKSNASTVKRELGFRIVKLERELKASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YK14</accession>
    <name>A0AAD8YK14_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L39</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_003132</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YK14"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1620.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein-like L39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1620.10">
        <property type="entry name" value="Ribosomal protein L39e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00629">
        <property type="entry name" value="Ribosomal_eL39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000077">
        <property type="entry name" value="Ribosomal_eL39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020083">
        <property type="entry name" value="Ribosomal_eL39_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023626">
        <property type="entry name" value="Ribosomal_eL39_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19970:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19970">
        <property type="entry name" value="RIBOSOMAL PROTEIN L39E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00832">
        <property type="entry name" value="Ribosomal_L39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48662">
        <property type="entry name" value="Ribosomal protein L39e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00051">
        <property type="entry name" value="RIBOSOMAL_L39E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1746525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="73" mass="8686" checksum="B03076E1D5878AF5" modified="2024-05-29" version="1">MCTSIGLHRQPEVNACFLSSHVEPSQKTFRTKVKLAKAMKQNRPLPQWIRLRTDNTVKYNARRRHWRRTKLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKS3</accession>
    <name>A0AAD8YKS3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001910</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKS3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615:SF80">
        <property type="entry name" value="GRIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615">
        <property type="entry name" value="MYOSIN HEAVY CHAIN, NON-MUSCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1081"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="840"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="922"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1081"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1104"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1120"/>
            <end position="1139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1139" mass="127467" checksum="C1B34911B210D41B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YL43</accession>
    <name>A0AAD8YL43_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YL43"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="121" mass="13909" checksum="FBA9CA408F77F621" modified="2024-05-29" version="1">MIHELKGSLERKCLFCRHPDPETQTQEEAARCARFAKMKRIEANDPTAMCDMGRSCYHEGDYKREGVEKDEKQLRHHLEQAAIGGHPDARYNLGIMEKEIERTKEQSIIGSSPPILDMMAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YL76</accession>
    <name>A0AAD8YL76_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002495</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YL76"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="212"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="212"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="324" mass="35777" checksum="6139BD314E3E0982" modified="2024-05-29" version="1">MPLSELRCAYMTCCGKFLCHGCTSAAVGSKAAFTSMGVRCALCREKTIVSDDEILQRVKKRMAANDGDAYFFLGCNYFDGTLGLRKNLAKAVELWLIGASLGSGTSQERLSVVYSEGWIVKKDEEKAVHYERLAAMKGHVISRWNLGNHEKDKGITKVNVSNAVKHWKIAAMAGWDHAMDHIEDMLSSGYPRLGVTVEIYEETLTAYLVSQNERKSDQREKDRGTRDCSVSDQEIARKKRTGSEASPLQQVQHLLALYAGRKSLKRHSYDAFAAMLIHTLSAQGIVDATTGNATNARIASWCELRKGCQGNSQLGAKEAQTSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMK8</accession>
    <name>A0AAD8YMK8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001077</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="515"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="815"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="515"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="826"/>
            <end position="836"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1749138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1349" mass="152985" checksum="869FC9D3A9A5F437" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMY6</accession>
    <name>A0AAD8YMY6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Monooxygenase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_000353</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMY6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF309">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="4">
        <location>
            <begin position="222"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="164"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="164"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1748414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="417" mass="46414" checksum="174B369A73EAD4A6" modified="2024-05-29" version="1">MTMMFCCMLHPTYVLVLITISNNVSQTKMNSEASDDATEYHPLVIVGGGIGGLVLALCLDQQYNQNSKNSSSKPLLPIHVYESTSAYTANAGGAIGLYPNGLRVLQNLNDTAPKLLSQVREAGCDYIYRRWMRHDGLEVAVAREDELLPDLVDEAGDDDVETAAATTTTSTAADSSTTANADRRPRRGSFGMLANRLSGRSLSSTTTSSSPRVETELQSLGIRRWKYQQVLYEACIEAGIKIHFGKRLQNAITTNDSKTVLHFKDGSKVMTSLLIGADGINSKVRNYVVNPTSDEEKQKSLEEFMPEYTGVTCLMGCANVPFMRGICFPSSATSKCHACYYPTKVPKDEVKEEEEDNATKTSMKWCFKSTFHHQLNVPIPGEHSHPMRQKLNVKNWQRNYVKMDGMNNFLHRWKVNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YNK7</accession>
    <name>A0AAD8YNK7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_000584</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YNK7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008964">
        <property type="term" value="F:phosphoenolpyruvate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021135">
        <property type="entry name" value="PEP_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30523">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30523:SF6">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00311">
        <property type="entry name" value="PEPcase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1748645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="87" mass="10310" checksum="92BB21FD66BB2FB5" modified="2024-05-29" version="1">MTLVPLDIREESTRHTLALDAITRELGIGSYKEWDEEARLNWLHQELNSRRPLFRIRDIEQNNLNLDPDTRKTLMVYKVISELDSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPQ5</accession>
    <name>A0AAD8YPQ5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">START domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_000969</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPQ5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1749030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="201" mass="22555" checksum="81BAEB6F423E512C" modified="2024-05-29" version="1">MKGPCHGMAFADFIMNTDKRQMWDPQIESVCELYPIFDLDAANIAMGFGKFGDCKKLGVGYTKTKAHPIGISPREQLTLCGIQEMHDGSALIWGTELEDWHDHLMPAGERHARARSHLFSIALVPTGEDSFDAEYSLQLDFGGNLPHWMTAPLVLDSVKSMFGVAQPFFETDGSEEVQKRIMEEKIQGEKFVDRNSILFTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D346</accession>
    <name>A0AAD9D346_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Thiamine biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_017129</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="1"/>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D346"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00565">
        <property type="entry name" value="Ubl_ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010035">
        <property type="entry name" value="Thi_S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01683">
        <property type="entry name" value="thiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34472">
        <property type="entry name" value="SULFUR CARRIER PROTEIN THIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34472:SF1">
        <property type="entry name" value="SULFUR CARRIER PROTEIN THIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="MoaD/ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="1" id="KW-0934">Plastid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1732086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="70" mass="8119" checksum="002868DCA6431467" modified="2024-05-29" version="1">MKETKTFFLNGEEYFSDKIINLLDIITYFNYNSSLLVLEYNNFICPKKDWDTISITDKDNIEIVTIVGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3M8</accession>
    <name>A0AAD9D3M8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Polyamine aminopropyltransferase</fullName>
            <ecNumber evidence="15">2.5.1.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_016615</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.16" evidence="15"/>
    <dbReference type="EMBL" id="JATAAI010000060">
        <property type="protein sequence ID" value="KAK1732716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3M8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004014">
        <property type="term" value="F:adenosylmethionine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004766">
        <property type="term" value="F:spermidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.90.10:FF:000025">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.90.10">
        <property type="entry name" value="S-adenosylmethionine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00198">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003826">
        <property type="entry name" value="AdoMetDC_fam_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030373">
        <property type="entry name" value="PABS_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016067">
        <property type="entry name" value="S-AdoMet_deCO2ase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001045">
        <property type="entry name" value="Spermi_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558:SF11">
        <property type="entry name" value="SPERMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558">
        <property type="entry name" value="SPERMIDINE/SPERMINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02675">
        <property type="entry name" value="AdoMet_dc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01564">
        <property type="entry name" value="Spermine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56276">
        <property type="entry name" value="S-adenosylmethionine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01330">
        <property type="entry name" value="PABS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="4" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 11" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0704">Schiff base</keyword>
    <keyword evidence="3 11 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0865">Zymogen</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="80"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="PABS" evidence="14">
        <location>
            <begin position="342"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1732716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="745" mass="84153" checksum="B0039714F261D73F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3V6</accession>
    <name>A0AAD9D3V6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Uncharacterized protein ycf33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_017207</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="6"/>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ycf33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3V6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008470">
        <property type="entry name" value="Uncharacterised_Ycf33"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05421">
        <property type="entry name" value="DUF751"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0934">Plastid</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1732164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="64" mass="7686" checksum="DD68B6B8FDE96624" modified="2024-05-29" version="1">MNNFWTNITRYPRFFISSMIGLVLIILTPFRNLFKTPKLRWILILFSLVFVLSLYFIIRSMVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D424</accession>
    <name>A0AAD9D424_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HTTM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_017193</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="3"/>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D424"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031383">
        <property type="entry name" value="Ycf90"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17088">
        <property type="entry name" value="YCF90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042090706" description="HTTM domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="294"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="473" mass="56406" checksum="EB42F3AEBA6B2A93" modified="2024-05-29" version="1">MFINNLHFWLSSVLSLLINIDQETILDFLGIDGTFNTEDYSYLFETTQVSTPVSFQTFKLIIQSIWDHYQHGLGFVDIENIALFILVLRFIFLSKKYNIKTGFFITCIGLGAGYLWYMHLRDLAYYYMRTLWMCPLTHNLAYDFSEIYYQQRSEFSKAGTRFDSNSFYGPAVRGFTELTSNDNYRYDPISMIWSYLPTDVKFLSDKLYYFITLKAIPQTYRFIDTQITNLSGMLWYTFIVRINKRYCPYLLRWHWTFLIGLEFIERPFIFVQDRLIYYLNSILIPNSYFREAELVTNLLITLVAAQYIFIILGMLHALCGQYFYFPFLTENTELHIGLRPKDSIYSGGHTIWQNKRAYMISRQASSKLKKYRFGTIRSAYSKLPRLWYGWLGRGTLDDLTTEDYEQYLKNKDNKDSIQKAKRRDSKIRSTYRQERLKNRFIQLLAKFGIKINTVNKNDEGDDLYEEFKKFSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4A1</accession>
    <name>A0AAD9D4A1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_016901</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000067">
        <property type="protein sequence ID" value="KAK1732420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4A1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042179821" evidence="3">
        <location>
            <begin position="28"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="285"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="315"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1732420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="394" mass="42499" checksum="7C3A22081E974AF4" modified="2024-05-29" version="1">MTASSKPSASAALLLSASALLINSSCGFTLPTHKTSVTASSSLARHNNNNNMALFAAADDNDKSGGTLFFASVAEEETTGESKPTKETKEPSPSASTNDDKSDTTEQQPSVKLFDTSTLQEANDALTSVGWAGVAPMQGEGEMTSEDPFVKQIDESIMEEMGVGLDQLLNPAKVVNLERDLYNLRNELATLTGATIDSDSNNTPLTTTQADAGGGGEDAEAIRTKITKKEKDLAMERRSVFRGWLKNVFLGQAVLSMALSFVMATHPDVLFGSFDWFNNVSNMDTSIKVLGFWWWWLFIVPSLRSRRPTGMEKKALDIAFLGTPLISLLSPVVTKDTGLIWVANFMVVAGAYGFAFAVGEDEDGGEDGGKDPAWLKFIYKSLDFGSGRERGARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4N7</accession>
    <name>A0AAD9D4N7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_016522</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000057">
        <property type="protein sequence ID" value="KAK1732810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4N7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.3310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003369">
        <property type="entry name" value="TatA/B/E"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33162">
        <property type="entry name" value="SEC-INDEPENDENT PROTEIN TRANSLOCASE PROTEIN TATA, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33162:SF1">
        <property type="entry name" value="SEC-INDEPENDENT PROTEIN TRANSLOCASE PROTEIN TATA, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02416">
        <property type="entry name" value="TatA_B_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="405"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="352"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="63"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="416"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1732810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="448" mass="49303" checksum="F41AFFC556257F37" modified="2024-05-29" version="1">MNNTKTMIRITAATMKRIGTLLLLAVGLLSTSTTYGFTNPVGVQRHAAARPLMPTTCNPHLVSSPPQRPSRSSTGSSTSLNVLGGDGGILGVGAPEIATILVVGYFVLGPSELYKLVKEIGKFVQNFRSLSTEASKQFESTMENQLELTELRKAQTELNNAFSFRRSINTDEAVDAFTENELFTEKAAAAAAATASGAAAVAEGEAEGATAVKKKKRLVRRKKKKVVVEEEPAPVEEELSNLEREIAMEYPDLDMLDEETPSADVQSKINEEDKIRAERMERLSGGGSSSSATTQEPDWFTASEEEIASEVLNTTPKDPALEAYEKNRFQSQLTAEDWNAQIMANEDKLSPLAMVMQRLAILEEEKNAADRRLEEEYERRMDNEDKFYLEKRRVLEEAIEDIQRDAFSDMTGGGGVEKKEEEGSVEGEKKKQDVESETVVNIGPKFSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D542</accession>
    <name>A0AAD9D542_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_016005</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000051">
        <property type="protein sequence ID" value="KAK1733288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D542"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015217">
        <property type="term" value="F:ADP transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080122">
        <property type="term" value="F:AMP transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005347">
        <property type="term" value="F:ATP transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015228">
        <property type="term" value="F:coenzyme A transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015230">
        <property type="term" value="F:FAD transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044610">
        <property type="term" value="F:FMN transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051724">
        <property type="term" value="F:NAD transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052217">
        <property type="entry name" value="Mito/Peroxisomal_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45939:SF5">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PMP34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45939">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PMP34-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="87"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="198"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="335"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1733288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="440" mass="49777" checksum="6DBBD0EAE1DA0F31" modified="2024-05-29" version="1">MKSIFIKQRTTLCLHAGKTMSSPSSKTAAGDNGGSSSIWLSIRRNQILRHVLIASIACSLYYLKIYHTNDLAKKAEQQQQQHQSNNNNNVIHALSGSLGSALSITIFYPLETVRTRLQVSDPNVTPSRWSFSLVYNIYQQEGLKGLYRGWWSLLVALMSLNFCYFYCFHSLRLWLLTFQNDDDISTYFQLLLYKLNGHKMMVDLIAGYLSGCVAVIVTGPLWLVNTRLKLQGVSSVDKGGNDSKNCQYDGMFHGLYTIYKQEGLSTLWKGTFTSIILSLNPAIQLAAYEMLKRHHLIVRNGSRVVWWIVSTIIYHARGSTGSSQENDAVVNSTDGSVMEHFINALLSKFVATLITYPIQLIQTRQRWSKTPDNNTNKPKPTRWVGAATMHDLTEIIQQQGLLGLYRGLESKLMQTCLNSALMFVAYEELVELLTKLLRHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5G9</accession>
    <name>A0AAD9D5G9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RCC1 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_015564</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000045">
        <property type="protein sequence ID" value="KAK1733709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5G9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="entry name" value="Integrin alpha, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051553">
        <property type="entry name" value="Ran_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982:SF8">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HERC2-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14312">
        <property type="entry name" value="FG-GAP_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041989817" evidence="6">
        <location>
            <begin position="22"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="4">
        <location>
            <begin position="348"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="RCC1-like" evidence="7">
        <location>
            <begin position="352"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="4">
        <location>
            <begin position="462"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="4">
        <location>
            <begin position="516"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="4">
        <location>
            <begin position="675"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="83"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="177"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="275"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="727"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="90"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="137"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="188"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="280"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="303"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="329"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="728"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="766"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="777"/>
            <end position="790"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF25390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1733709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1194" mass="127937" checksum="01DC6B22F0D7FAE7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5T8</accession>
    <name>A0AAD9D5T8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_015253</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1733995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052201">
        <property type="entry name" value="LRR-containing_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24111:SF0">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24111">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="107"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="377"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1324"/>
            <end position="1345"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="319"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="389"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1733995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1345" mass="150062" checksum="AA0CE9315C38B704" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6Q9</accession>
    <name>A0AAD9D6Q9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013123</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1735987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6Q9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008557">
        <property type="entry name" value="PhoX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35399:SF2">
        <property type="entry name" value="DUF839 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35399">
        <property type="entry name" value="SLR8030 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05787">
        <property type="entry name" value="PhoX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="350" mass="37635" checksum="3D1D1A80C4BC44CC" modified="2024-05-29" version="1">MTSKTLIRHHCHVQILQAGQICSVIPASGTNRRMSLAVCVCALWGVEEHCCYCKSNSTNETTNESTLMPSTSEYEEGTTFPTHVPVIAPSGNPIEIQVPTQTPTILTSTERPSDVPISLTPTPSTSSLSLTTTAPTTGQPTTAQPVSEVPSDYPTLLTRTPTLHPSVAQSDSPTEQFLPGELLLSNKELGIELSSGLEAKLIASTGKKLELVDGKKSSLSFHSRMDGAGIIDLGDRGYVYVSNSEESAGGVYGLQFNLAGEIVDYTNLLSNTKRNCGGGLTPWNTWVSCEEWKRGQCWQVSADPNSQNYLMAQKTMIGGSQGGRFESVATDNRIEQSPVFFATEDSKLVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6W2</accession>
    <name>A0AAD9D6W2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Succinate dehydrogenase assembly factor 1, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013303</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6W2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034553">
        <property type="term" value="P:mitochondrial respiratory chain complex II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20268">
        <property type="entry name" value="Complex1_LYR_SDHAF1_LYRM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045295">
        <property type="entry name" value="Complex1_LYR_SDHAF1_LYRM8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675">
        <property type="entry name" value="LYR MOTIF-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675:SF1">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="101" mass="11371" checksum="EFF9F921B89CC1DF" modified="2024-05-29" version="1">MAPSARLSGLQKDVLALYRSILRETIRKDRKPAALDSHHVPLNQLLHSNSNSSTSFARDKFRKEASLVKRSDFKTIEYKIRKGQKQLKLLQMPGVNLVGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7U8</accession>
    <name>A0AAD9D7U8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcription activator GCR1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012099</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7U8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022210">
        <property type="entry name" value="TF_GCR1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12550">
        <property type="entry name" value="GCR1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription activator GCR1-like" evidence="2">
        <location>
            <begin position="643"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="747" mass="85461" checksum="2F1ED2783298CEDA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D836</accession>
    <name>A0AAD9D836_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012889</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D836"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1736289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="346" mass="38409" checksum="3C4AD749063C4108" modified="2024-05-29" version="1">MMAPFFSIDDTRKIVYDVVSLAIIDQSSQQASTVSDSDKDDHLCLDVLLLHGMAPVGRKCWGLKDHTSNNSLMKNGKLASDNVNTFIEAIRQHSNNKISHARLIMPDRPGYCDSDAAPAVKEQGCDDGANKGYSYAQFATDMLRVVAHATAGDDDDDGELDSARKRSLIVLGTSSGGPCSLAIRNRILSETSSLPNHIFLGTIICSSDCPYSHPHCPQAVTSEDTKDLNGRSIQQYVQDESLKRFRRNSKHGFVTDYLLERTDWGFDLAAPSHVSCDDRANHRCNRVHMYVGGEDDYKSIRLGAQFLRELIGDDARLQILEEEDHFYASRKPQLLAKLLATMTSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D912</accession>
    <name>A0AAD9D912_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D912"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="129" mass="13800" checksum="45B3FCBBEA71E9CE" modified="2024-05-29" version="1">MNSPELSLDMNLDSPSASDVVADESGSGDGMNCGENNASTVGITHDTHYQQHEKYHDSSNHGHNGADASNYSSFGSGGGTDIGDTFSSDKIDCDKMTKLIEEWKDELSMMRVKNAILLDDLVKVGANNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9D3</accession>
    <name>A0AAD9D9D3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000024">
        <property type="protein sequence ID" value="KAK1737655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9D3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000093">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="1">
        <location>
            <begin position="56"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="317" mass="36005" checksum="88F4A98CD11B79FE" modified="2024-05-29" version="1">MYHIFYSNKEGGLNMQSSTRGAMEELDCLLVKEQSSQYQISPTLLWNLNGKNKKCSSPLRWRHAICDWYYDFVDHFHFDREVVGVAVNYFDRYTSINAVSLDDNENALSTYHTVAVTALFLAIKLHATSCEVDDLQELRNRALSKILYDTPQPKNILDMEMNMLKALEWSVNPPTLHQFAFLFNKFHPSREICTGSGSYIYEATRYQVELAIFVPQLLAKFKPSIIAFAAMKNTEEKIAAGNPVPTTDMKLSYEALTSHSGVVVDSTAVAQCQMLLKRVCPELPDLEHFHEAATHGTIIDMQVDRNFANSPTIVVDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9Z8</accession>
    <name>A0AAD9D9Z8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9Z8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="435"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="478"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="522"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="544" mass="57864" checksum="72EC7AB471501336" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DB17</accession>
    <name>A0AAD9DB17_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_009818</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DB17"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050502">
        <property type="entry name" value="Euk_RNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025">
        <property type="entry name" value="OS02G0815200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025:SF1">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="266"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="155"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="235"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="349"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="171"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="184"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="352"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="367"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1739275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="384" mass="41297" checksum="CAAF661BEB4E02AE" modified="2024-05-29" version="1">MASTQLNSSQPTTEMEATEGTSARKPSPPATKWHESSQNAIVSSNGFATDFITHSMYNARAQAQVAQVYPNAQVQMGCPPFVEGGGGGGGSGAYNPWPNHQHQQGTVFAGHYGPPQLQPMPQPLLPAMMGPLGLGHSNSNGVSIVDTITVKLRPGGDALTPPPVLQRALSDPSQLNLNQQPARSPSPSPPHPHPPYGENIPLLINVHKLRYDKRLKALIDKKDLMLNYNYTDNQMSGPAITPNQSPPPPGAGQGGEEEDFPGSPKKDLFVFHLPNGMTEGQLHDLFSQVGKLHRARIQFHTEEGKRATKGYGFVTFKRFSDAVVAVHSLNGFSVGGKVLAVTYCRDTPRPISANNSVSTNNGTNSARNRKARRGQRQRRASASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DB77</accession>
    <name>A0AAD9DB77_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008368</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DB77"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="286" mass="30825" checksum="BF2D0E303CB74D95" modified="2024-05-29" version="1">MAALGLGPKKVTQPAMRGANFSSVASRPTSTPIFTASYSSSIPTTRAPDMNRNNFPSLGGGPKPFVPTSYGGASSSRASPNLAGVTFHLWGVQEELNFPAPPAAAKKKGSVSSAFAPKKPLQWTTYYNFLRPQLQKDLLISRGPEHSFASGSKEPERYVDEAVSLFDRGVTDKAFWEHVPCLIESCPNKSGVNRAMNHLESLRMANQMQEMEFGGGGGSAPKKPINYVLPAKKKTNSWGGQTAKASASNTPVASLEAKPKHLHQITRPKLVEVTAKRAKTRRKTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCE4</accession>
    <name>A0AAD9DCE4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006837</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCE4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050745">
        <property type="entry name" value="Multifunctional_regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189">
        <property type="entry name" value="MYOTROPHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="45"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1742272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="505" mass="56934" checksum="EA6CB9D28902959A" modified="2024-05-29" version="1">MEETKKNNERRAIAQQLHNAAQVGNIQEIQAIFEKHQLPIDSHRRGNTALHSALYHNQDGLLLDYLLEQGANVNSPNSKGYTPLDLSIIYCKRGKAAEKLIGAGAQWKEKYDEESSNGMPFKMPLTFAGLTPLEVARKYKNEEVVELLTAKLHHDETNYCQAISSDADVSTTNDAPPMKKWHSICPICKDTVRFPTSMSRILIDQAILEERLQNVNGVLLDSKEKSGKNRKKYVARKYLDQFVSHANGKAYEKLCGIKYHAVQNMRLRKEISESMGVLSAVQQCCYDLKGGKDGGNAKEEDTFHLENVFLIDLCSGRGLTTALGGALHDDDDNDDGNGNSSNNFFLSIDRMLPHTVPHFLQDGENRKYLSRDVMSETLFAELQEIVSEQLDLGRTPILVGMHLCGVLSERAVEFFERIPSIKGIVLSPCCLPKRHEQKKGITKFAKGQVDYEFLGSNEESGELYNYFKWNHYLKEMMSKSTPHVNSFTDDEMHTEKNAVVVGIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCW0</accession>
    <name>A0AAD9DCW0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008342</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCW0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1741090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="145" mass="16398" checksum="C3730CF75ECB9F6F" modified="2024-05-29" version="1">MMDRTHLLEQLLAMNKFGSLQSSLVEFAADFARRSANFYRNDVKATLEGERKDMFIQAAAFLIEFGTQNDFDRFGKLSIKSVDLFSVFINAVLDTSGQELLRDILNKCLLQYSITDVDTLISSWTVRNQTSQTFSNSISSCQEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCX8</accession>
    <name>A0AAD9DCX8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Exocyst complex component Sec6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_006618</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEC6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1743021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051601">
        <property type="term" value="P:exocyst localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.70">
        <property type="entry name" value="Exocyst complex component Sec6, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010326">
        <property type="entry name" value="EXOC3/Sec6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042532">
        <property type="entry name" value="EXOC3/Sec6_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21292:SF1">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21292">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT SEC6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06046">
        <property type="entry name" value="Sec6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="405"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="500"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="22"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="77"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="130"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="175"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="239"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="257"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="312"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="349"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="428"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="449"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="503"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="539"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1743021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1474" mass="162407" checksum="FECB936B3969F233" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDA9</accession>
    <name>A0AAD9DDA9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">tRNA-splicing endonuclease subunit SEN54</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007382</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDA9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000214">
        <property type="term" value="C:tRNA-intron endonuclease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000379">
        <property type="term" value="P:tRNA-type intron splice site recognition and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024337">
        <property type="entry name" value="tRNA_splic_suSen54"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21027">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21027:SF1">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="401" mass="43971" checksum="670853208EFF32FE" modified="2024-05-29" version="1">MSGSSKGDETLPLGVYVPPPTTTADGSDGSPEKQQHDGYVRIPDAKGRNTCGFSRPIGTVMETITVASKKRSHSLISKDLECTKDHDITIDHDATAESETNTKSETMQQKRTITEERLHPEEALFLHMRGLLRIEYNHETMSTQDLFCSMLPECKISLPAYLAYAHLRAQGYILIRYSAERIKLLLARSLNAREKDSSNIAEGGERSNDNNEVSESTQNTDIDNSSSSNIAEGGENSNDNKLEVSESTKNADIHNSSNNSWRQAKQKLSDDVATASPPCVVLFDEWNSNCSHDLNTRLAYFAYNPNSNFRRSNPGLPDFGVAIMPFQSSGVSVPSFDTISALVALCENRRNDGGDETEDSITAASNEIPLRIATVADCGAVIVYGVTRGDVPVIDKKKNDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDI5</accession>
    <name>A0AAD9DDI5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Derlin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_007261</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the derlin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDI5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007599">
        <property type="entry name" value="DER1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11009">
        <property type="entry name" value="DER1-LIKE PROTEIN, DERLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04511">
        <property type="entry name" value="DER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="247"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="271"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1741688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="281" mass="31156" checksum="D593EC0C5A608D91" modified="2024-05-29" version="1">MPPPRHGGQGNVRQMDDTGGPQAWFESLPVITRYWFGGALAVTVMCNFGFLPIMKMVWTWDRVWENFEIWRFLTPFLFVGKFDFNTLMALYMLQSYSNRYEMEPYNTGGGGGTADYAFALMFGAISIVVTYPIMGMLLPAPPVFARTLMMFVLYVWSKRHPTAPTSIWGVQFQAIYLPFAQIGLSIAMGGMFSDMVHGIICGHLFYFLVDVVPIVYQKDVLHTPQFLIDQIGIGAYVPPANNTAAGNNVWSPPGRVNPPSDAAGPSRGHSWGSSGQRLGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEK0</accession>
    <name>A0AAD9DEK0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mannuronan C5-epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEK0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024535">
        <property type="entry name" value="RHGA/B-epi-like_pectate_lyase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12708">
        <property type="entry name" value="Pect-lyase_RHGA_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhamnogalacturonase A/B/Epimerase-like pectate lyase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="291" mass="31321" checksum="D521E836FE62A467" modified="2024-05-29" version="1" fragment="single">YQAQDFGAVADPTVDNRAAIQDAIDAAHAAGGGMVVLQSGTFGISKQPGDNGAILMKDNVFLKGNGIGKTVLRVVGPTCCRLTGIIRSPWGEATKNYGIADLTLDGNRENTKGLIDGFYNGGRPGGTITDEDVWIVRVEARYCSGYGFEPNERNERLTITESISHHNGRDGFVAVYIIDGVYKNNIAYENDRHGFNVITSSYDLLLSNNIARDNGGGGIVVQRGSLDTPVPHNIMVAGGESSRNGKEGVLLLMCYNVEIKGVDILENGSYGVRIHDPRLKSCECVEQSDHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFA5</accession>
    <name>A0AAD9DFA5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytoplasmic dynein intermediate chain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_006154</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFA5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045503">
        <property type="term" value="F:dynein light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010970">
        <property type="term" value="P:transport along microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050687">
        <property type="entry name" value="Dynein_IC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442:SF22">
        <property type="entry name" value="CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442">
        <property type="entry name" value="DYNEIN INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="646"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="105"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="259"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1743533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="767" mass="81117" checksum="0F0EBBDB98C183A0" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFC1</accession>
    <name>A0AAD9DFC1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Tripeptidyl-peptidase 2</fullName>
            <ecNumber evidence="15">3.4.14.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_005686</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides.</text>
            <dbReference type="EC" id="3.4.21.62"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal tripeptide from a polypeptide.</text>
            <dbReference type="EC" id="3.4.14.10"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.14.10" evidence="15"/>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008240">
        <property type="term" value="F:tripeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048384">
        <property type="entry name" value="TPPII_GBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048383">
        <property type="entry name" value="TPPII_Ig-like-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022229">
        <property type="entry name" value="TPPII_Ig-like-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046940">
        <property type="entry name" value="TPPII_Ig-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF14">
        <property type="entry name" value="TRIPEPTIDYL-PEPTIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12580">
        <property type="entry name" value="TPPII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21316">
        <property type="entry name" value="TPPII_GBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21223">
        <property type="entry name" value="TPPII_Ig-like-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 8 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="11">
        <location>
            <begin position="34"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="Tripeptidyl-peptidase II first Ig-like" evidence="13">
        <location>
            <begin position="557"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="domain" description="Tripeptidyl-peptidase II galactose-binding" evidence="14">
        <location>
            <begin position="724"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="domain" description="Tripeptidyl peptidase II second Ig-like" evidence="12">
        <location>
            <begin position="855"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="882"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1697"/>
            <end position="1781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="2365"/>
            <end position="2391"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1206"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1697"/>
            <end position="1706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1709"/>
            <end position="1722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1751"/>
            <end position="1761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="2382"/>
            <end position="2391"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="281"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF21223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF21316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1744089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2391" mass="265640" checksum="8F5F4C52E0045141" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFS9</accession>
    <name>A0AAD9DFS9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004773</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFS9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017956">
        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00929">
        <property type="entry name" value="ATHOOK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00384">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="158" mass="16878" checksum="F7DA73DBB1F694A9" modified="2024-05-29" version="1">MPTPAKTADSGKKRGRSPKSASPEKKTSSSPIKKRGRPPKPLPNSSLPSPIKRPRGRPPKKEKANSSIKAPVSLFDPRLPPPPPPPPPVNNPFYQKFVMEYWQNNYFYNQQVTGASAVMNIPGIIGSPMPSVAAANLDGKGPAALKSDAGDEVESTSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFX9</accession>
    <name>A0AAD9DFX9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Chloroplast protein import component Tic22 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_004666</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFX9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007378">
        <property type="entry name" value="Tic22-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33926">
        <property type="entry name" value="PROTEIN TIC 22, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33926:SF4">
        <property type="entry name" value="PROTEIN TIC 22, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04278">
        <property type="entry name" value="Tic22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041978742" evidence="4">
        <location>
            <begin position="26"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1744133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="341" mass="37480" checksum="EABFDA4491ECFF65" modified="2024-05-29" version="1">MMLSLFSSYFATALLLSSSLLSANAFSTPTAPRGLMARGLSMQKSSDIDNGVQNVDTKEYYNSDDKTRRQILINTAVAVLAASSSSPSLAEEMKDSNKSGVVSTGKLASLLKSTPTFAIVDARGVPYFVVGEDAKLTSYFFLSYTEAKRILDVAISSSDQAIKETKKEIKQKKGTVTKEDEVEIGINPWKQARITSVPLDLAVSLCSKGKLAGAYFRLAPAESDIEDALQIDGSDDLPEGKVPLFYVEDFTIADQEPLYFQKEQLITDWKREQKSGDKTAEPVVKVSELFATITEMVRPDGKDEELKSIVFVAPLESEKRAKQCLKGEKEPFRLGERNIVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGH5</accession>
    <name>A0AAD9DGH5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004281</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGH5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042054446" evidence="2">
        <location>
            <begin position="22"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="300" mass="33102" checksum="649893944B98DB04" modified="2024-05-29" version="1">MKISALIICAIGATAVAPSSAFLSLINKANPSLSKYAEAQEDAMLKIHLDIGQVEMKDGKPLITGNRLGIDNLLLQLRGKESASPKHASLPGADGPNPQLSSGPKSLVVVNQGSYVDLAGTTRQFGRWCLGDGVEEQCKGRSPHCSLPPSRRSQEKRCCNPQGRFFLTFPLWTSESLQDLRDRKAKAEEKATEAIERHASEVRMMQETNNPLMKALHFRNACKAHEDLDYSGYRSYQKVPLERDMIHLEGNLHLCSLGTIWTKKEGWFADHELLGSARAFQDDLAKVTGVADKKISNLHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGW6</accession>
    <name>A0AAD9DGW6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001304</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGW6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.780">
        <property type="entry name" value="von Hippel-Lindau disease tumour suppressor, beta domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037140">
        <property type="entry name" value="VHL_beta_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036208">
        <property type="entry name" value="VHL_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49468">
        <property type="entry name" value="VHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041923582" description="Fe2OG dioxygenase domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="506" mass="57055" checksum="DE4B7D4F599DE4E0" modified="2024-05-29" version="1">MMRLLNYLTFASIFCSAGALESNVVSNLSDLPFDENDHLNAHILAFPASGPCGALMKAQIEATFLYGHVPVAVEGDAAEKLFGSNIPIKPSAVTDCPAVCLDRGVDSSLVAYPLPEKYYNPENETHQSLEQFVASKSCGRVEFGFINYSGKDLALYWVNGDAETYMYPFLQKERNTRFVTTFIGHTFRAKDPETGEVLLEHTVDFNGVMGVSNHINYHRKRDIREEVKRTMAGEWTKHLQVKRTFSALGFDKGHLPNDVFGSMRAFYYNNRAPPNRLMEEWDSKGLYVNFWETDCNFIQIPWELKFIWQERLKDVVQEWVGETEIEQTDLYGMRQYETGARLLTHVDRITTHAVSLIVNVAQGNLTEPWTVEVYDHANRLHEVVMEPGTIVYYESAKALHGRNSPLAGGFYANLFTHYRPIGDPNWYMKDNPEGTPAPLLDVGKCELVGKPNEYSQGAVKCENDAIGPHLSPKMITATSGDDLYDLWLSVGPSFEDDENAVASDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DH14</accession>
    <name>A0AAD9DH14_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_001454</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DH14"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="141" mass="15638" checksum="BC946F339F62298D" modified="2024-05-29" version="1">MTPTERRDYVQNLVEIMLAANCQPLQQKTGARTGLSLLSTDSTTVNPSSLLGANTGEGRVYINRHISVPIVPLVAEESSLQTHETELHPYHTLLFPKLTPSEILQDLQNEHVESAISINPNSLSIIRILRQVLPITHPEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DH76</accession>
    <name>A0AAD9DH76_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RAP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003392</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DH76"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="183" mass="18629" checksum="8B7C581CB802EF77" modified="2024-05-29" version="1" fragment="single">CLVVNILLVGFLMGDLRLLSDGEFLRLHPNHRLHAAGTETTEIAAKNRIITVALLLLTIFIATALCRAVAIVAIIQEEGAALEGEGEVIVIGVLLAFLVAVAAPAVAVAIGADRSVAVAVVADRAEAEGEEAGAHGRAGEGKGAGAHGRAGEGIGIGEDDAIDVIRARMNATLHVLSFSSCVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHD9</accession>
    <name>A0AAD9DHD9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_001844</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHD9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="130" mass="14543" checksum="D3F55F1A6067237B" modified="2024-05-29" version="1" fragment="single">HLFAILSTHPSPRRRPTIKNTVATSKRTDTFGNMTTAASNTIAELQSRLSDLELSKTHNDVSGIIQKERTEMLLSLRKIMEAMKTDAAGGASSKELEKLRAENEELKKINAKQNYRIEHLVNNLRGVADK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DI63</accession>
    <name>A0AAD9DI63_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DI63"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="108" mass="11312" checksum="80B71E36E3BA0EFF" modified="2024-05-29" version="1">MLGRIRSARRAASSLHLTPGRSSNSRSTISAAAVHRQLLQHRPTVAAALPSSSSHFFSTTSAPLSSAFLKSYDEHVAERAAMANGKLGGIAPKPLDDGKESCRAKGAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIV6</accession>
    <name>A0AAD9DIV6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002522</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIV6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="168" mass="18087" checksum="C1B2BDF433CB9572" modified="2024-05-29" version="1">MKGGGGGGPSSKKSSSNNPPKQPSSSTTNTTESTTTEEEQSSSWWEDQSYYTTLTTLLDTGLYKAYQAELVPTVSAASQLLQLYIEMKESAALVLRECRWSVGVPLSGGLVVTTATTNNGSGGGGSRLRKMIMGKDDNDGYKIAIGGGSQNVFLVEELWWMKWGRIFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DK02</accession>
    <name>A0AAD9DK02_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CBS domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000948</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DK02"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="51"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1749009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="159" mass="18356" checksum="4BA7F298AFE4452A" modified="2024-05-29" version="1">MVSKQVGAVVIVSTHKDDTEKSIPERIITKTDILQAYRRRVDIDESCEHIIRKNSLVTCNPDDDRDTVASILEREKMHHVIVVHEEHFVGIVSSWDIAAECAKDNRAWPYLRSEDGSLPQFPRFEEEVLPPAYNPQKAVSILNHEHDFFMDDLDLESFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-12-02" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6U3XS79</accession>
    <name>A0A6U3XS79_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tetrapyrrole-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_006934</name>
        <name evidence="4" type="ORF">SMAR0320_LOCUS17324</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="HBGZ01024416">
        <property type="protein sequence ID" value="CAD9619683.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6U3XS79"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046906">
        <property type="term" value="F:tetrapyrrole binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16383">
        <property type="entry name" value="GUN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1770">
        <property type="entry name" value="Gun4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008629">
        <property type="entry name" value="GUN4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037215">
        <property type="entry name" value="GUN4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34800">
        <property type="entry name" value="TETRAPYRROLE-BINDING PROTEIN, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34800:SF1">
        <property type="entry name" value="TETRAPYRROLE-BINDING PROTEIN, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05419">
        <property type="entry name" value="GUN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140869">
        <property type="entry name" value="GUN4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042404967" evidence="2">
        <location>
            <begin position="19"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="GUN4-like" evidence="3">
        <location>
            <begin position="76"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CAD9619683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1742369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="233" mass="25903" checksum="8654B76279162231" modified="2020-12-02" version="1">MRFLLSATAILLAGSASAFAPAPICRHNNVVASSPLFMSEAATAESTSMADAGKPPAESEADSNVSDDLIPTKLPSDVGMDYVPLATMLATGQWAEADQFTRDALIVLAGSKEKGRTFVYWTEVKRIPSTDLATIERLWNKFSKGKFGYSVQKKKWRQSKNDFEAWCKKIGWTTTDGDVERKKRWFGASEFIYDLKKAPEGHLPLTSALRGTSLIKELLNHPVWENDDWKKEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2Q3N5</accession>
    <name>A0A7S2Q3N5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_004691</name>
        <name evidence="8" type="ORF">SMAR0320_LOCUS23612</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="HBGZ01032992">
        <property type="protein sequence ID" value="CAD9631845.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S2Q3N5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101031">
        <property type="term" value="C:protein folding chaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051966">
        <property type="entry name" value="RPAP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46423">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46423:SF1">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="7">
        <location>
            <begin position="524"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CAD9631845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1744158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="584" mass="65263" checksum="F166E8D3802A547F" modified="2021-06-02" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1LVR4</accession>
    <name>A0A8K1LVR4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 13">Cytochrome b559 subunit beta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">PSII reaction center subunit VI</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12 16" type="primary">psbF</name>
        <name evidence="15" type="ORF">QTG54_017190</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="16"/>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2021" name="Front. Plant Sci." volume="0" first="0" last="0">
            <title>Chloroplast Genomes for Five Skeletonema Species: Comparative and Phylogenetic Analysis.</title>
            <authorList>
                <person name="Liu S."/>
                <person name="Xu Q."/>
                <person name="Liu K."/>
                <person name="Zhao Y."/>
                <person name="Chen N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CNS00100</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="12">With its partner (PsbE) binds heme. PSII binds additional chlorophylls, carotenoids and specific lipids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterodimer of an alpha subunit and a beta subunit. PSII is composed of 1 copy each of membrane proteins PsbA, PsbB, PsbC, PsbD, PsbE, PsbF, PsbH, PsbI, PsbJ, PsbK, PsbL, PsbM, PsbT, PsbX, PsbY, PsbZ, Psb30/Ycf12, at least 3 peripheral proteins of the oxygen-evolving complex and a large number of cofactors. It forms dimeric complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12 13">Plastid</location>
            <location evidence="12 13">Chloroplast thylakoid membrane</location>
            <topology evidence="12 13">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12 13">Belongs to the PsbE/PsbF family.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MW679506">
        <property type="protein sequence ID" value="UAM91393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_010200903.1">
        <property type="nucleotide sequence ID" value="NC_058701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1LVR4"/>
    <dbReference type="GeneID" id="68638031"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009539">
        <property type="term" value="C:photosystem II reaction center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009767">
        <property type="term" value="P:photosynthetic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00643">
        <property type="entry name" value="PSII_PsbF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006241">
        <property type="entry name" value="PSII_cyt_b559_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006216">
        <property type="entry name" value="PSII_cyt_b559_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013081">
        <property type="entry name" value="PSII_cyt_b559_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01333">
        <property type="entry name" value="cyt_b559_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00283">
        <property type="entry name" value="Cytochrom_B559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000037">
        <property type="entry name" value="PsbF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161045">
        <property type="entry name" value="Cytochrome b559 subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00537">
        <property type="entry name" value="CYTOCHROME_B559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 16" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="7 12 13" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4 12 13" id="KW-0349">Heme</keyword>
    <keyword evidence="9 12 13" id="KW-0408">Iron</keyword>
    <keyword evidence="10 12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 12 13" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="11 12 13" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="16" id="KW-0934">Plastid</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="5 12 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 12 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="Photosystem II cytochrome b559 N-terminal" evidence="14">
        <location>
            <begin position="6"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <note>ligand shared with alpha subunit</note>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1732147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="UAM91393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="43" mass="4880" checksum="3AD2A737552B1B6E" modified="2022-08-03" version="1">MAKNINQPVAYPIFTFRWLAVHGLAIPTVFFLGGITAMQFIQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XR23</accession>
    <name>A0AAD8XR23_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_017074</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000078">
        <property type="protein sequence ID" value="KAK1732249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XR23"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1732249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="192" mass="22014" checksum="66C92D824F16DD46" modified="2024-05-29" version="1">MYKDQTSNQFCLRLLATFGSPKFDSKEPLHILSADSRFPDVDPRCALRDGNHFLAMFPVDRMRACLRDCYVNGGSIERTMSERNQRVRGGGSTAVGTDDGVEMEVDGISDDAAAGLSWLFHGEWYDDLPCDIPVRCDLDNEEEGGKRSWFDLRKRRKLQNKKEDELAVYRPKSMTRLIGYWINVFVRILAYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSS7</accession>
    <name>A0AAD8XSS7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000054">
        <property type="protein sequence ID" value="KAK1733052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSS7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="826" mass="93404" checksum="630EB5EE0FA165DA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTT2</accession>
    <name>A0AAD8XTT2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015796</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000048">
        <property type="protein sequence ID" value="KAK1733508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTT2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="215" mass="23738" checksum="CAB99368CC3B3464" modified="2024-05-29" version="1">MRGGVCRRHGAYSIVSHNSTTHRYQARKSDQQSQTSKSLTLPNIVLCMKDKDYAKVMNEFIKILDGMEYNATVEEMGGEILLALKQKFHIADENGDSIDDKAALQKLVQCLNNQCSRIQTMPKLGIGSPNASIYPKMRPEPPEPVSYTKYFEDEDEDEDVSSTAAVNEADDDANEEKKRSATEDDNPGATKKSKADGEGEQILAAPPGCKTLFSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XU63</accession>
    <name>A0AAD8XU63_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000048">
        <property type="protein sequence ID" value="KAK1733503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XU63"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="748" mass="84290" checksum="ECA53EE0B2A1F215" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV12</accession>
    <name>A0AAD8XV12_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015258</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1734000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV12"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05271">
        <property type="entry name" value="NDUFA9_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051207">
        <property type="entry name" value="ComplexI_NDUFA9_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126:SF11">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="51"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="390" mass="43702" checksum="E4A48F36B0CE1CFB" modified="2024-05-29" version="1">MALRTAALKPLRKSLLLTRAFSTELPRITERRPNETGHGGRASDAGVKVALFGATGFLGRYVSSGLGSNGTLTYIGTRGDEFAYRHLRPHHELGRAKFSYYSSRDKQSMADIIADADIVINLIGKYYDTKALENTDSFPFLNYKVSTSVWEANVEVPKMIAELCTEMQVDNLIHVSSAAAGNVDSASEWARSKAEGEKEVLKAYPWATIVRPTQMFGHEDKLLNLFAKMAERFPVIPLVDGGHALTQPVYVDDVARTINRIVDDPEMFEGRRVDCFGPQDYSYAELAKFVYDITEQEPTLSDVPAEVVKYGANVLQYEGNPMLTPDMVDLWTEDYLPEMTAEKYAAQKQLGKVFTMKDLGVEATPIEKMAFKYLYRFRKGGHFILAEGYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVE1</accession>
    <name>A0AAD8XVE1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mitochondrial carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_015198</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVE1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041979939" evidence="10">
        <location>
            <begin position="23"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="5"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="105"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="211"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1734195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="302" mass="31773" checksum="4B63D53BDEBEE1C2" modified="2024-05-29" version="1">MTAAGALIIKMVIAAFSGMGAATVCHPLDVIRVQMQTSGSTYNSAGEAARGIYKNDGLKDGLYAGVSAAYLRQWLYGSCRIGIYAYLLENAQNANIAAGLEKNAIPLSSKMLMGLTSGGIGSFIGTPSELALVRMSNDKKLPVDQRRNYNGVGNCIARIAKEEGAPALFTGAPATVLRACLLSACAMGITSEIKMRLSKSGHFGEGGKAFGGVPMLFCATLVSSFCANTVANPFDVVKSRMQSSAAEYGSMVDCFVKTVADEGVLKLWSGFVPAFLKLAPYTVISLLLTDYITKIITGKEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVZ7</accession>
    <name>A0AAD8XVZ7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014566</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVZ7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033579">
        <property type="entry name" value="TMEM128"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20479">
        <property type="entry name" value="TMEM128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="113"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="146" mass="16526" checksum="912CC2B5517664FF" modified="2024-05-29" version="1">MNLDLEQSAPLRRRGPRPEGNDDAMPMIPPPPPGLPPRHPLQLMKRTAIMGGTLYAMHELYQGKKNKKKVEYENFRAATHASIVLILIAWISFHKSLSPLYGGFKTMLIMIGFGFGVLLQAALMIPVWGQNFLSFVILTFFLQQYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWK5</accession>
    <name>A0AAD8XWK5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014453</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWK5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="147" mass="17149" checksum="B6C0904E0C6816E0" modified="2024-05-29" version="1">MLQQMICRGCDYANKVREIEARLQQTCPFCRHPTPTTRRSQQERNEKSRKNDPVAIREIGMKHCSNGTAAGLGMRVRIIYLHFCIGRGKVLRRTRKRNYSIWKRLQLRPSQARYDLACHEGEMKGTIEQSNISSLLPTSDVIIQYKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XX98</accession>
    <name>A0AAD8XX98_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XX98"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="117" mass="12813" checksum="A01A3CE532382AE1" modified="2024-05-29" version="1">MATKRQTTDSYANAVAAIAMYGWLTNLAWSKSEQYVGRFLSTILSIVFGLSCLLQIFGLIAEFMDIEAQPRTGDNQRIAALHAAVLGAFYKRNKGGVIISCGDNFMLAIEFDGPLQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXB2</accession>
    <name>A0AAD8XXB2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Histone H1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_013874</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the histone H1/H5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXB2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031492">
        <property type="term" value="F:nucleosomal DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030261">
        <property type="term" value="P:chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045910">
        <property type="term" value="P:negative regulation of DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00073">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005819">
        <property type="entry name" value="H1/H5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005818">
        <property type="entry name" value="Histone_H1/H5_H15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11467:SF36">
        <property type="entry name" value="HISTONE 24-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11467">
        <property type="entry name" value="HISTONE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00538">
        <property type="entry name" value="Linker_histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00624">
        <property type="entry name" value="HISTONEH5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00526">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51504">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="H15" evidence="8">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="68"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="73"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1735260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="146" mass="15675" checksum="9286CD6E11D6B0F2" modified="2024-05-29" version="1">MSYKAGIVAAITELKDRTGSSTIAIKKHMQENMAADKKWLNGMFLKALKDGVAAGDFVKVKASYKLSPAAKAAAKKKAAPKKKPAPKKKAAPKKKAAPKKKAAPKKKTAPKKTTTKKPATKKTTTKTTTKKKSAPKKKTTKKTTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYJ8</accession>
    <name>A0AAD8XYJ8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_013446</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYJ8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1735740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="91" mass="9483" checksum="FE4E89A657BEBF1C" modified="2024-05-29" version="1">MNPTIKTAILILTGILVAIIGTGSGFTNIAAVPHQLPSSSKRVTSEMKLAAVSFEFELDNPLIETDEGIVPARKCAVCIGSGFPWCPVGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYK8</accession>
    <name>A0AAD8XYK8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_013534</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYK8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01763">
        <property type="entry name" value="Ubl_SUMO_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000684">
        <property type="entry name" value="RNA_pol_II_repeat_euk"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00115">
        <property type="entry name" value="RNA_POL_II_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="129"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="163"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="181"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="215"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="258"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="284"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="309"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="352"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1735828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="447" mass="48014" checksum="65664F68E2932B2E" modified="2024-05-29" version="1">MAKKKNRNKNNTNKSGASPPTQNNGCNKNDGASPPSTKTTSTSNNEERIQLKLINHSTKFTHIVRVRPTTPFERVADNFLQKYNNSNSTVKKEELQYQYNGKVILPSDTPTTLGLLQRGGEVEISVVHTPLKGGGRRRRVDSSSDDSDSSVSYNPDSPPYSPTSPAWTPDSSSSDDDSDDGPPPLSSRGGGPPPPLAARGGNNKNDEPPPLSKRDAKKKKKKKKKGSNKERRSKDDDDDDSSGDGASIPPLAERDDSTSSSKSSDSSSDSSSASSYLEARRNDFNANRNSSRGKSVTPPKEISVRSDSTSDDDVSSSGSDDDDEDDVDYEFGGDDDRSTGSGTSDDMPNLVGRDESSHSSHSSDDSSRNSMPALLAKRVPKEQAARKKKNSATAAAAALAEKAAAADQNTFVLTCIGVPVISNRRVWGDLEAKIRTSLLIFVELFLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYS0</accession>
    <name>A0AAD8XYS0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cohesin subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_013551</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008278">
        <property type="term" value="C:cohesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007062">
        <property type="term" value="P:sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039662">
        <property type="entry name" value="Cohesin_Scc3/SA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056396">
        <property type="entry name" value="HEAT_SCC3-SA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020839">
        <property type="entry name" value="SCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11199:SF0">
        <property type="entry name" value="LD34181P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11199">
        <property type="entry name" value="STROMAL ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24571">
        <property type="entry name" value="HEAT_SCC3-SA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21581">
        <property type="entry name" value="SCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51425">
        <property type="entry name" value="SCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCD" evidence="3">
        <location>
            <begin position="494"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="249"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="935"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1448"/>
            <end position="1573"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1277"/>
            <end position="1331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="35"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="53"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="143"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="249"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="267"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="940"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="963"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1448"/>
            <end position="1457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1458"/>
            <end position="1470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1480"/>
            <end position="1503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1527"/>
            <end position="1542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1545"/>
            <end position="1555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1735845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1573" mass="173811" checksum="48611650BD22E433" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYV6</accession>
    <name>A0AAD8XYV6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycosyl hydrolase family 18 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_013596</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYV6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00035">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018371">
        <property type="entry name" value="Chitin-binding_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00187">
        <property type="entry name" value="Chitin_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00026">
        <property type="entry name" value="CHIT_BIND_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chitin-binding type-1" evidence="7">
        <location>
            <begin position="309"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="351"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="709"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="351"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="716"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="783"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="814"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="825"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="318"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="323"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="341"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1735890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="994" mass="106608" checksum="A2610CAF4497841D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y006</accession>
    <name>A0AAD8Y006_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="5">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_012645</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="5">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y006"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="214"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1736623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="432" mass="46840" checksum="18352F23C2A68B6F" modified="2024-05-29" version="1">MFHVGRFDPTAKPKAAPASASSAGGAKKRRTGDGSKGKSKKSKKDDDVIADAGAREAVVIDDAPTQLKNDDDKGNHSDSSSSVPSSSESDDSSVESAQDNVHKSTLKVIAPSQPISGDSRKANRKRREQDDEAIDDFDADFDIVENSAAKDDTIITAATLRQNEHTPFTATIEEAAKTWNLPQFLVNNLKADSYENFFPIQCMVIPDVIESERNAHLRGARDVCVHAPTGSGKTLAFVLPLLTALHNQSPTSTGGARGLRRLRALVVLPGRDLAKQVYDVFVRYAKGSDIKIGLAVGGGNKKGDLANERRSLVVETYNDTIREIRTDDGALLRRKVGGLYESASARLRHSFEPTSLGKALDAYDGTLKSDSGPQVFPKVGGRSAVDILVCTPGRLMDHLETPGFTLQHLKYLVVDEADRLVNQPYQNWVGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0K4</accession>
    <name>A0AAD8Y0K4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_012763</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0K4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000299">
        <property type="entry name" value="ABC transporter ATP-binding protein/permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013897">
        <property type="entry name" value="Duc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF1">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08588">
        <property type="entry name" value="Duc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="259"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="86"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="440"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="31"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="182"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1736741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1172" mass="127012" checksum="4DAC0F593DA698A4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1E0</accession>
    <name>A0AAD8Y1E0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HU family DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_011705</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1E0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13831">
        <property type="entry name" value="HU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="entry name" value="IHF-like DNA-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020816">
        <property type="entry name" value="Histone-like_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="DNA-BINDING PROTEIN HU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175:SF3">
        <property type="entry name" value="DNA-BINDING PROTEIN HU-BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="IHF-like DNA-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00045">
        <property type="entry name" value="HISTONE_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042035940" evidence="4">
        <location>
            <begin position="24"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="20"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="76"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1737419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="196" mass="20767" checksum="25FB683D01D64C32" modified="2024-05-29" version="1">MTRTLLSVILALFVATSSSSVDAFTPPSSIGERGITSSSSSSSSSIAPLKLKGASNTNSISSRGHTARPATAMYAAKKKSSTTKSTKKKSSTKSGDSEAPVNFKKAEFVSAIAQKTGLTKSESEHALSSILSIITEELSVGRKRISLPGFGTFKLTYRAARKGRNPKTGEEIDIKESYSPSFTASKTFKDLCNPDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1S0</accession>
    <name>A0AAD8Y1S0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Chitinase</fullName>
            <ecNumber evidence="13">3.2.1.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_011899</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="13"/>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055372">
        <property type="entry name" value="CBM96"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF033679">
        <property type="entry name" value="DNRLRE_dom"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF333">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24517">
        <property type="entry name" value="CBM96"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8 9 13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 9 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="GH18" evidence="12">
        <location>
            <begin position="184"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="11">
        <location>
            <begin position="563"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="11">
        <location>
            <begin position="620"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="907"/>
            <end position="926"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1737613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1388" mass="152477" checksum="5CFBF9289CA19F82" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2M4</accession>
    <name>A0AAD8Y2M4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011166</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2M4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="256" mass="28608" checksum="DA7682D494FFCBF1" modified="2024-05-29" version="1">MWLFRTAIDARKAGHFEGGFGFEQNILLRVEEVRAEANYMECILRGRMPFGYAHIVQVLVDVSFWSGFDPIRVDTLIAETNSGSLRWMYGLEDMPIPLKIIEEGGSNLDLFVLPDEGISVEEVAQMEAMEEAEKASSSLGGIFSEQIVGVGPRTSIIVEGDTVEDEQQTYQEEFEETQAIMSAPPGSVFVPGIDDVDEEGCTTGSDDDEDDCEPKPNEGEDFGEMAYDQYLETLNEEYEVTMRKYEVDAFIKDTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2U9</accession>
    <name>A0AAD8Y2U9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_010654</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2U9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="51"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1738624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="226" mass="25765" checksum="D9A239F2DA5BCBE5" modified="2024-05-29" version="1">MVDYTLLNKFARKRASLGRDLTDDENEAITAEFMKESGIHINSKICIMDGQSMCPRSGRKLRCPCNEVTYCSEACQRHHWTIHKMTCKALAKKKKKKKKPTQATSAQPAHGLTEEELEYIRIEAFMAENKGVKHAIEECAWQLGEHPLVIGGGQIRYGPNGEEFKKGDVGKIYREEIGVEWDGDKRFGLGPYVQQKTQFDWIAKAKGGKSLKKDNLEELMKELWQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y368</accession>
    <name>A0AAD8Y368_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Battenin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_011235</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the battenin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y368"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051453">
        <property type="term" value="P:regulation of intracellular pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003492">
        <property type="entry name" value="Battenin_disease_Cln3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10981">
        <property type="entry name" value="BATTENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10981:SF0">
        <property type="entry name" value="BATTENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02487">
        <property type="entry name" value="CLN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01315">
        <property type="entry name" value="BATTENIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="437"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="463"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="102"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1737941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="543" mass="59577" checksum="41ECEDFCE453E260" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y474</accession>
    <name>A0AAD8Y474_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_010151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y474"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1738835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="198" mass="22888" checksum="B28B3D2A2F31B283" modified="2024-05-29" version="1">MSQWCVNNGITIICLELAKILPRDQRYNADALMNRVLSLSHQELRRLCSENEHFFRQEGPYIRSYKQFVEMKRGDIVALHTKGGMSGGRGPPQTLSFGVIQDDSLAVMSREEAMQKQCPWDLNPRIGFMVKKVKWLRQGELKAVRGPNQVNWLAEFSPLWLMQVGERQGKFLTDAIRKMGSEQFMRNTHSIDNQWTMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4E5</accession>
    <name>A0AAD8Y4E5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010309</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4E5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="406"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="425" mass="45418" checksum="7A626CCC92B7C578" modified="2024-05-29" version="1">MPSRLEENNLCLHSKTQTDPFVAMSSKQSEQLQTAAAPPQTSILLHPNEFAYDEEKRLGRANGNTYQRRPGIDNVHDGQIMVRLKKKRYIIIDYGYIPKPEDYAISNASAHISIPEGAGQQRCATKDCPRVGVPVMLYDSEPSEAMSLYLRGGLCFSCQRAVNEKRRTKRKRKPEEGLPFDQVNLGASGDVRSLGSSGSRFKVNNEVVELNSDAIIINGAVAGTRSRGPGYQHPEIGADLLQIMSELSNDTMSLVSNLSTVGISSPAAANMLYQKAFLSASKATYLLTQWKASYDEHSYAAAAAAAGAVPVPPPGHGYNPYDPNAVDHAVAATEAALGSNNNTNGGAPHHHLYSMNHAMMNNAAATSLYGMGAMHHPAAANSNNHNGMIGVPTLAHVPAGAASMANIKSSNPQAPSKNGNRSAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4P1</accession>
    <name>A0AAD8Y4P1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010391</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4P1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041944375" evidence="2">
        <location>
            <begin position="31"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="128" mass="14230" checksum="2F7E3E6B2EDB64FC" modified="2024-05-29" version="1">MISASPNHLFRNAIFLLLTLTILTTRQTAASATGQQSASTHPSKPAQAEPQRQHHHHLHSNIIPVKHLNFHGPAVPTDGTAKNEFDRLNNRRYYGGRVTRAQVHEAVVKTARHSRTNEIYVMGVASLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4U6</accession>
    <name>A0AAD8Y4U6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009357</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4U6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="268" mass="29732" checksum="E2BAF3EC9B652E95" modified="2024-05-29" version="1">MLAADKLQLQSTLKQQATALKEKEFNLHHNNFMTVGTQAAVLAGLDVTMFIEFQPPANEEWPFVIIPRVLKFVYYVCITSAFCANMLVVSQTTILSVLGASLALRGPDGSMMTATDGLYLERAMVFRSFGMGLILTIASVVSVVWLHLHWEASLTCCILALGTLMKMRQTYLRIVKKFDFDESLTVDFQDIFDGPAAIQAIPVRRIISQGLRGMGVSSGSDSSGDGDKKRRISTKGSHDADMELNDEEIALVRRQRMLNGQQSRFQTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4W7</accession>
    <name>A0AAD8Y4W7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Growth-arrest specific micro-tubule binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010496</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4W7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031514">
        <property type="term" value="C:motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048870">
        <property type="term" value="P:cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039308">
        <property type="entry name" value="GAS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025593">
        <property type="entry name" value="GAS8_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31543">
        <property type="entry name" value="DYNEIN REGULATORY COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31543:SF1">
        <property type="entry name" value="HECT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13851">
        <property type="entry name" value="GAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Growth arrest-specific protein 8" evidence="2">
        <location>
            <begin position="217"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="290"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="442" mass="52036" checksum="34D8EBD03A353951" modified="2024-05-29" version="1">MTKKSKSKKKAKEVDPKEKERLDLLERAVTLRGETEKENALETQFQAQSESLKQFWEIEKKLREDRRQKLREKEHRLQQTKDEHIVNLGEYKRTIKQLLFSNQDELSQNAIQSLLDYQSQSKEYLREMNALFDELGIATRNMEQTISWHQNLKNSLHHDCSEEITAVREDASRVIARLATYTGNQLKMTHAEFEMKLKKEIQQLEIQNEVEIKATIDKNRESMQNMRQESNATINSNLDTITALTKELIMLREQYRKDVHVLRELQAENEGIMSPLETNSNDLQRLGSDLDAFYMQKRDLETRRKQLKQAEKELNDIKWDHEVLFQHHERLEQECKECKLKYQEAVYSAQQKSNMQNMKLERKLDQVKMEGEKSSAVLSQILIKADVDLDSVDQSIVVDVVADKNNKVKMLNDELSRIKDAHATMRKRYSCLVDKHLEGNKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5V9</accession>
    <name>A0AAD8Y5V9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009239</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5V9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1720.10">
        <property type="entry name" value="endopeptidase domain like (from Nostoc punctiforme)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="325" mass="36570" checksum="1DE0BC23E719C0D6" modified="2024-05-29" version="1">MKKMASQRRFFQQFITNLSKRRTKLALQLSASAAVASMPIMYWSHNARKERAEREHEVATRIRIPSVQTIDDLMVEKCQPGDVILFDRRSECCAAGFSAALGCLLGKTILCDEEDGTRSVERGSYEHCGVVVPGLSDAQGAQHDSSNLCLLEATSGNGIVCRPLLTRLEMSRSRSVMLLPLSCPGEHRLQDVITGLEDESELSEKTKFLKKTMNDELIKFRDKWLTDSQSQGYENQHSYLSIMGAFLYLTNLYPTFPIPVSPSAWLVVSALQECGAAMKLNEKQAQQTRVEDFTRDGRFFEKNSVRLRPGWKFLSPVAMRETSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6B9</accession>
    <name>A0AAD8Y6B9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Arylsulfatase family protein</fullName>
            <ecNumber evidence="7">3.1.6.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_010044</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.-" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6B9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16025">
        <property type="entry name" value="PAS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.720.10:FF:000047">
        <property type="entry name" value="Arylsulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050738">
        <property type="entry name" value="Sulfatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42693:SF33">
        <property type="entry name" value="ARYLSULFATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42693">
        <property type="entry name" value="ARYLSULFATASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00149">
        <property type="entry name" value="SULFATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase N-terminal" evidence="6">
        <location>
            <begin position="7"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="675"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="714"/>
            <end position="724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1739501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="906" mass="100786" checksum="E8A0F3A7C4EA9419" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6P2</accession>
    <name>A0AAD8Y6P2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008964</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6P2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="178"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="237"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="370" mass="39765" checksum="3DB2EDE3150D1B03" modified="2024-05-29" version="1">MKLPLFSSQKVCNDDENNDISRERQYEDSMAASPVRQQAQCTWAAPHHAKNTTFNYGGGMRRVQSANASRPRGAVGAASGMNNPLGMAHKSRSHSQESRSSRNAVPSEQLPIPQCKNTLLEIARTKSDQTDLRRMYDYATWNMYDRIVSARNKKRISEADNTDDLDALINGEGEKESSSSSKNNDKPSSIVTTTATTSCNSSFASSPNQAAIACKGSGIIKTSGNNIKTTATIKKVQASTSSNTTNTTTSASATSTSSTQAMSTTSSTYQQQASRTTSTTTTTNTTNATQSSLHHKLRSINKAFSSHDTDSSQGGTAATESTSTESEDSFGNSRSGCNSPATFPGFMVGRSHRTMSQGSEDDHFIFQLDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y744</accession>
    <name>A0AAD8Y744_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidylinositol-4-phosphate 5-kinase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009594</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y744"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.110.10:FF:000002">
        <property type="entry name" value="Phosphatidylinositol 4-phosphate 5-kinase 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215:SF14">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="196"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="240" mass="26496" checksum="72C3F127E77444F4" modified="2024-05-29" version="1">MDINKCHGTVKLTYDDGRIYEGEFVNGKPHGQGKMTIAGTGAVYEGEFSNGKLNGKGTCTYDDGHNYIGEFKDGHMHGEGTFTLATGLVYEGEFKNDRPNGKGMMKRRDGSIEYDGDFKDSQQHGEGTAYLRNGNVLYKGGWKADEPHGMGIMNYANGNIYDGEFDDGNKHGQGKMTYANKEVYNGEWMNDKRHGKGTITFPNGDVFSGEWTSQQKRDANTQDVDETGSVAKRPKVEVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7M1</accession>
    <name>A0AAD8Y7M1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">D-2-hydroxyglutarate dehydrogenase</fullName>
            <ecNumber evidence="6">1.1.99.39</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_008254</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.99.39" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7M1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051990">
        <property type="term" value="F:(R)-2-hydroxyglutarate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2190:FF:000001">
        <property type="entry name" value="D-2-hydroxyglutarate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-bd_oxidored_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051264">
        <property type="entry name" value="FAD-oxidored/transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43716">
        <property type="entry name" value="D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43716:SF1">
        <property type="entry name" value="D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1741002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="393" mass="43190" checksum="F3982BA3242AFAE9" modified="2024-05-29" version="1">MEYMNRIYKLDEYSGVLTCDAGCILQSLHDYAEEKGYLFPLDIGSKGTCQIGGNVSTNAGGHHFFRFGGLHGTVVGMEVVLADGRVLRMNVDVSDDDNNDDCTHRFQQSSASLRKDNTGYDLKQLFIGGEGTLGIVTKVAVACPALPTSKNVALLVCNSYSDVLQILKTSKEELGEILSAIELIDSNTMKFVQKYGSGIGDHLISELLSPEAEAADKQPLFILVESQGCDQESDSSKMDAFLTSLYESSTIENGFLAQDSKHIEEIWGIRESCNPSVARAGYVHKFDVSIRIEAYMEVAEEVSDALENANLSDLTVCVWGHVADGNAHINIVSGQCDKDAVVQKQLKICILFSYEEKWLDFCGTRHWTIEAQVHVTNQGWSCLGAHVTDEEFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7M4</accession>
    <name>A0AAD8Y7M4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_009186</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7M4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051063">
        <property type="entry name" value="PDI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45672">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45672:SF3">
        <property type="entry name" value="THIOREDOXIN DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="48"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1740236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="142" mass="16431" checksum="BA6085F8B09D4A22" modified="2024-05-29" version="1" fragment="single">RPTRNTPLHRNPPHHQNLRLIGNNRQRQHTLAPQILRPLVRPLCRPLPILDQAASHLAGKLSIGKIDCTIEKKICKGKFDVRGYPTLKYYRDGEFSDYPLGRDLDSIVSFGEKMSQSAVKVVKDVGRFMRCWWGVRMGLWRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y821</accession>
    <name>A0AAD8Y821_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008012</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y821"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042259427" evidence="2">
        <location>
            <begin position="19"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="257" mass="27354" checksum="520DF952E50E6230" modified="2024-05-29" version="1">MKSTTVATLFAIIGTTTSFNAQPSYGRHSHPNTASYNSLRDMASYPETFENGFGHRQGQGGGGHQQGGGFDDGNWRTNAGYSQGPGGYRDMETNPYYDEGWSQSARPSRGGPMGGESFGGRRGGGPMGGGPHRSADGFDPFGAYSPAMGMSRSDRRMDQGDLFMNSDAMGMRSDRTMRGFTYDGRNRDGMYERREYGMDPGMMFEDPEFGPPGMMGGMDGMQGGMQGGMQDMGMMGGGGGMQGMGGGMQQGMGRMGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8B6</accession>
    <name>A0AAD8Y8B6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PS II complex 12 kDa extrinsic protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8B6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36327:SF1">
        <property type="entry name" value="OS03G0731100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36327">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042047820" description="PS II complex 12 kDa extrinsic protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="202" mass="22004" checksum="1051E0C7ADBA48E2" modified="2024-05-29" version="1">MQQLIALGLILLVSSASAFQIQSSMTQQQHRSHHTQQPLAATPTNNNNDSDDVSNTNNNPLHSRRNMLLGLSATNLAFLSSYASSANADVLRSAGCANGEGEACADLAEGNEFIQNLQKKSAQNKEANQREALNAYYMKNYPDVFAVSDKKMVKKLDGSYALFSAKEVDNLNKAGKIRIEYPTSKGGRIADLTQKPILVLNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8Q0</accession>
    <name>A0AAD8Y8Q0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Histone-like transcription factor-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_008665</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8Q0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22929">
        <property type="entry name" value="HFD_POLE4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050568">
        <property type="entry name" value="Transcr_DNA_Rep_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252:SF54">
        <property type="entry name" value="CHROMATIN ACCESSIBILITY COMPLEX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252">
        <property type="entry name" value="HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="142"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="142"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="321"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="42"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="59"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="95"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="321"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="336"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1740570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="366" mass="39854" checksum="B9B9EB52BAC04F03" modified="2024-05-29" version="1">MAKSSTKDDTDAVNDAHINDDTSMKEMSAAEEANIVGATADDTNDTDVPIEEDENDTNNEDKVEEADRANDDEHDDDAASKSSEKDEENEDNDKDEANKPNSKDNNDGTPSKKRPAPSDAPSNAPPPTSNEEDNTPLPTLPLKKGRTAYFIFANDKREELKQKYQGEGVAALSKATGELWKQLQPAEKEVYETQAAQEREKYRVDKQRLIDAGVWPESGGGSGGGGANDAGEYDEDGILFPIGRIRKICKLDGDVKGMSKEATLLVAKATELFASKLGSEVVTMAQMSNRRKLLPDDVVEVCSMKERFMFLKDDLQDLIHEQKEVQKEKENEKASSGGGSKSDKSGGGGKPTSASLLSYFGKVHND</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8V1</accession>
    <name>A0AAD8Y8V1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_007376</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the beta-catenin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8V1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043495">
        <property type="term" value="F:protein-membrane adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071562">
        <property type="term" value="P:nucleus-vacuole junction assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045156">
        <property type="entry name" value="Vac8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47249">
        <property type="entry name" value="VACUOLAR PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47249:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="68"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="216"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1741803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="727" mass="80535" checksum="3226617D00253AA4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y910</accession>
    <name>A0AAD8Y910_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">JmjC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_008439</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y910"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041070">
        <property type="entry name" value="JHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050690">
        <property type="entry name" value="JHDM1_Histone_Demethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002653">
        <property type="entry name" value="Znf_A20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23123">
        <property type="entry name" value="PHD/F-BOX CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17811">
        <property type="entry name" value="JHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51036">
        <property type="entry name" value="ZF_A20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="JmjC" evidence="14">
        <location>
            <begin position="332"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="A20-type" evidence="13">
        <location>
            <begin position="703"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="307"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="620"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="623"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1741187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="747" mass="83626" checksum="B3CD444488083C3D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9M6</accession>
    <name>A0AAD8Y9M6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9M6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="234" mass="26529" checksum="D3F640DCF049C078" modified="2024-05-29" version="1">MINCNIQSKPELNGQSGIIRKATVKDHENSDRIPVLVHGMAKPISLKLSCIRLPPQKQYNTPEELMKLNSIETPEDVPEPSQLSKRERQQLKNKLNSNDPAIAKVLQAIQSGDAGFTRMADPEYKRGVKEFTQPPLNAMLPAEYKKMFKNCYELSNHPKAMDAIKIMNMRKAAKQRLMTIHPECVHPNGAIAVPLDSEFMRLQENIENKIRGDEGLAFVFKRLDELGLYVNPIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YA14</accession>
    <name>A0AAD8YA14_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ubiquitin-conjugating enzyme E2</fullName>
            <ecNumber evidence="5">2.3.2.23</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_007270</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YA14"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23810">
        <property type="entry name" value="UBCc_BIRC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46116">
        <property type="entry name" value="(E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46116:SF39">
        <property type="entry name" value="BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="4">
        <location>
            <begin position="303"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="531"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="95"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="565"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="582"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1741697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="592" mass="65972" checksum="9F75D333CEE92F12" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAR5</accession>
    <name>A0AAD8YAR5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_006598</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 5"/>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1743001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAR5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43811:SF19">
        <property type="entry name" value="39 KDA FK506-BINDING NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43811">
        <property type="entry name" value="FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="7">
        <location>
            <begin position="386"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="234"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="234"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="252"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="267"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="285"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1743001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="475" mass="52367" checksum="14765BD97CE1FD17" modified="2024-05-29" version="1">MWPSKEEVFRLVSSCILGIITRESQVVPPSNYNNTMARKSQRKKKVDYKKLTLDELSDLHDADDEEIEEDEAFNSDDEKEFGQYFDNQGREVVNKSYLGLTVPLSGDEGSVVHTEIKKGHKMTLSSVCLDVPSGDFRQIKLMVRCIYLGGTDEPWLCLGNFLGQKNGGMAVSPSIPINLEAVGPCKVEWKVEGKIPSVFASNGINIFGKIVPIMQEVFSDDDLSVDYAGAFMSEDEECEDDEDEEEEEVVISTANGSDAVHSQDNTNTDKKDDVAKPKKRKLSDAEDGAGEEEGETAEKSTNNKLTKKQRKQLAKEKAQQLEDTLSASRNDEDESKTSKKKKKKKKNGTETEELSRPTSLTRERRLPSGVTVRDVLVGTGAPVKSGKKLSLHYTGSLLSTGKVFDKNHSKQHPLVFRQGTGEVIRGLERGLEGMKVGGERVISIPSKLGYGKKGAGVDIPPDSDLSFEVKLLKVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YB90</accession>
    <name>A0AAD8YB90_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">T-complex protein 1 subunit zeta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_006630</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1743033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YB90"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03342">
        <property type="entry name" value="TCP1_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000038">
        <property type="entry name" value="Chaperonin containing TCP1 subunit 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000058">
        <property type="entry name" value="T-complex protein 1 subunit zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.260.10:FF:000017">
        <property type="entry name" value="T-complex protein 1 subunit zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000004">
        <property type="entry name" value="T-complex protein 1 subunit zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012722">
        <property type="entry name" value="Chap_CCT_zeta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="143"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="149"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1743033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="575" mass="62444" checksum="74F7B4101ADC8A65" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCF5</accession>
    <name>A0AAD8YCF5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Zinc finger CCHC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_006353</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCF5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025829">
        <property type="entry name" value="Zn_knuckle_CX2CX3GHX4C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13696">
        <property type="entry name" value="zf-CCHC_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="5">
        <location>
            <begin position="542"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="5">
        <location>
            <begin position="614"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="5">
        <location>
            <begin position="729"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="263"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="332"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="502"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="557"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="655"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="15"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="126"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="137"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="269"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="287"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="338"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="348"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="388"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="453"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="559"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="569"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="655"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="670"/>
            <end position="687"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1742756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="853" mass="93355" checksum="F3FBA1AD6F0F2ED1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCX9</accession>
    <name>A0AAD8YCX9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004689</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCX9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="391" mass="44204" checksum="7205B44B00122736" modified="2024-05-29" version="1">MTEVEERTPLEAAQKAREIWLNAKKQSDLDEVERLYRWALSSKKNLETDDDGGSGRPKKKAKQGHCGLDRSDYINASKERLASIGFTCRLAKRVLDYPDESKESDDSSPNADHKQQKAPPCTIVDNFLSQAELERLQSVFQSTTANYWTSHDYAVEPPSPYFSYVLSLEQIETNGFGFIGELIQKVLHCPQLAEKFPKLPNTRYVEMWAHNRPHASGHQLHFDSDDEGRGGVRNPIISTILYIADGDDDIAGGPSMVTNQKLSDEKLATKGWMSSPKPYRLVAFDGRYLHGVVPGKGTQEGRRVTLMFAFWDEIKIRRGLGPGSARPFPKNILPPWASQLAKPMETAENENQYDNCKTAEPIKLDRVYETLDGKAWNKQEMPAYDEVFQGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDS6</accession>
    <name>A0AAD8YDS6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">N-acetylneuraminate 9-O-acetyltransferase</fullName>
            <ecNumber evidence="11">2.3.1.45</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_005786</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PC-esterase family. CASD1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.45" evidence="11"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDS6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047186">
        <property type="term" value="F:N-acetylneuraminate 9-O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00229">
        <property type="entry name" value="SGNH_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012419">
        <property type="entry name" value="Cas1_AcylTrans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13533">
        <property type="entry name" value="N-ACETYLNEURAMINATE 9-O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13533:SF1">
        <property type="entry name" value="N-ACETYLNEURAMINATE 9-O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07779">
        <property type="entry name" value="Cas1_AcylT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="145"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="231"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="284"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="404"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="498"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="536"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="564"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="633"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="970"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="domain" description="Cas1p 10 TM acyl transferase" evidence="10">
        <location>
            <begin position="192"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="172"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1013"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1038"/>
            <end position="1051"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1743165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1051" mass="119274" checksum="7BCBE2EF0360083B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEZ1</accession>
    <name>A0AAD8YEZ1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Signal peptide peptidase</fullName>
            <ecNumber evidence="10">3.4.23.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_004735</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase A22B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.-" evidence="10"/>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEZ1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098554">
        <property type="term" value="C:cytoplasmic side of endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098553">
        <property type="term" value="C:lumenal side of endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043527">
        <property type="term" value="C:tRNA methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042500">
        <property type="term" value="F:aspartic endopeptidase activity, intramembrane cleaving"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033619">
        <property type="term" value="P:membrane protein proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007369">
        <property type="entry name" value="Peptidase_A22B_SPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006639">
        <property type="entry name" value="Preselin/SPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000241">
        <property type="entry name" value="RlmKL-like_Mtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174:SF23">
        <property type="entry name" value="MINOR HISTOCOMPATIBILITY ANTIGEN H13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174">
        <property type="entry name" value="SIGNAL PEPTIDE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04258">
        <property type="entry name" value="Peptidase_A22B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01170">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00730">
        <property type="entry name" value="PSN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="449"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="476"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="526"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="577"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="629"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA large subunit methyltransferase K/L-like methyltransferase" evidence="9">
        <location>
            <begin position="203"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1744202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="687" mass="76054" checksum="885E200AF2BB089B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFZ2</accession>
    <name>A0AAD8YFZ2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Electron transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_004883</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFZ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052378">
        <property type="entry name" value="NosR_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30224">
        <property type="entry name" value="ELECTRON TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30224:SF4">
        <property type="entry name" value="ELECTRON TRANSPORT PROTEIN YCCM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13405">
        <property type="entry name" value="EF-hand_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12801">
        <property type="entry name" value="Fer4_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042156024" evidence="6">
        <location>
            <begin position="24"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="334"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="449"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="596"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="643"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="866"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="922"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="696"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="788"/>
            <end position="823"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1744350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="985" mass="109671" checksum="9A1811BC88576950" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YG85</accession>
    <name>A0AAD8YG85_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tic22-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_003471</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YG85"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007378">
        <property type="entry name" value="Tic22-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33926">
        <property type="entry name" value="PROTEIN TIC 22, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33926:SF4">
        <property type="entry name" value="PROTEIN TIC 22, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042068154" evidence="4">
        <location>
            <begin position="30"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1745547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="437" mass="48814" checksum="D8551685E42F4F78" modified="2024-05-29" version="1">MRASSPQQLLLLSLASAALLLSTATSAAAHTINLSNLLGSSTTIPAYERILSQPVFQVTTPWGSPYMLFEKYKDEEKAIEMESGNSGSDDTADMDKFSRVQQKDDMQDTRPISLYFMDEHDARALADEMKQMKHMKDSDLRVTCSSLGKAVRSASNLGRGLPTGQGIDDKTGKLLTMDDGGSLRHKVVPSKRELFYAARCAGRERVGCFGDSPNEDADLLLQPQDVIEANKMQARRASKKNTARRIQKARQLEKEGLMESPTDRLRREYAHMEGQVGLPVFYSEGLLKKPPALRRIFQGAKSAWATSSLTPLYFSYEDLMKDWSIMRERSNNKNKIPEKPPQVEVFNMLDVVTSIDKDQWRAERRSELVRDQKGLVGKIPILHNLINTGKKSASKKSGLEKVVFVPSSLGIQAKERISAAGSMKTRLRPMRAWGKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHB4</accession>
    <name>A0AAD8YHB4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phytanoyl-CoA dioxygenase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHB4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051961">
        <property type="entry name" value="Fungal_Metabolite_Diox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37563">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G03330)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37563:SF2">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G03330)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="804" mass="89925" checksum="ADAD6AD005B447CC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHG0</accession>
    <name>A0AAD8YHG0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mpv17/PMP22 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_003241</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHG0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF121">
        <property type="entry name" value="OS09G0315000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1746634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="486" mass="54411" checksum="2EC6933514D1EE29" modified="2024-05-29" version="1">MTTQRYHRPAAVTRAAFAGLITAWMIASSFAFTLQSLVSTTHVPHPFTLVSRRHQFQPQRIRKNRAAGSSTFLRVSVEPLPPVLPESQEVHDDLIISVSEQNNSNNFTQNANGMVEVQTLPAGETDEQHMERARMGDDVEELTHLLAHDEIDLQRLVSPSVPVSYDENGMVYADAFVGIATTDNSMSVAIEEQDYPTFIKFLFRKDDNGQTLASKLFNFTLLAVSFGFVFFSVFNIDKGMTRGWSPSEIGMRIPLDTWASYENSLSEKPVATKTIINVVIYLLGDWLSQTLFQKNNVLDFDAARTIKNGIVGMCFGPAVHEYYEFSDWILPVDGVTIGITNRAFKILMDQTIYLSVKCSIYIIAIGLLNGESLGTGSENVKNRIKPIMFAAWKFWPLVHCVTYGLIPARHRILWVNSVDLVWNAILASKARDDDPSGDDYEGENGIENLETKVGDSNLSWQDRFNNSILADSVEVEEFDVVKDAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHP8</accession>
    <name>A0AAD8YHP8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Threonine synthase</fullName>
            <ecNumber evidence="5">4.2.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_002113</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.1" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHP8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004795">
        <property type="term" value="F:threonine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004450">
        <property type="entry name" value="Thr_synthase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051166">
        <property type="entry name" value="Threonine_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00260">
        <property type="entry name" value="thrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42690">
        <property type="entry name" value="THREONINE SYNTHASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42690:SF1">
        <property type="entry name" value="THREONINE SYNTHASE-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="4">
        <location>
            <begin position="16"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1746769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="256" mass="28451" checksum="EACB1B69FADE7E9D" modified="2024-05-29" version="1">MLGNFFEYFLSTGSNDGRLAVLGATSGDTGSAAIYGLRGKKGVDCIILYPNGRVSEIQERQMTTVPDDNIHCVSVEGTFDDCQDIVKASFANQEFRDRVKLGAVNSINWCRVLAQTTYYFWSYFRVTDAEKDVKEVNFSVPTGNFGDILAGYYSKRMGLPVGDLIVATNENDILHRFFTQGEYHREDIQATISPSMDICVSSNFERYLFHLAGDDSTTLANWMSAFESTGKLTISGKMLDKARADFKSPGLILMPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHV2</accession>
    <name>A0AAD8YHV2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA (guanine(46)-N(7))-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_003743</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42708"/>
            <dbReference type="Rhea" id="RHEA-COMP:10188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10189"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.33"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.33" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHV2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008176">
        <property type="term" value="F:tRNA (guanine(46)-N7)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003358">
        <property type="entry name" value="tRNA_(Gua-N-7)_MeTrfase_Trmb"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51625">
        <property type="entry name" value="SAM_MT_TRMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042118612" description="tRNA (guanine(46)-N(7))-methyltransferase" evidence="8">
        <location>
            <begin position="20"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="218"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="231"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1745819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="442" mass="50384" checksum="508438272638EFE1" modified="2024-05-29" version="1">MIAFLCAITVLLLIHSACGAAGSSQFGHRIHFLHHSNFNTYHMHTMMRARRLPTTMAFQRLATSSYTGRRFQQHITTDIANLATPTRRRRRRNNFKLVMSMDNSDATATTRVTQYTINDSVCPPTDPDTLTKIVQKHIHALPRYWFSRPVANHTAEAFQEAMDFVNEYREKKQFPDASKVNVILDSGCGTGKSSVILGEMYPNCVVIGVDQSIARLSRNKSYQQSDDSEETDSKKDTSVHTDVQENNINNQDTNQNDNVLLLRAELSDFWKCCLSSTQWQERASIYKHYLLYPNPYPKKSRLKSRFYAHPAFPLLMMTIMMDGDTSDGDVLSAEEDKLVVRSNWEGYLNEFKSAVGIWQDCGGTFSEWKKTYLASDIPDPADGWHPTNESPVKFESSGPNRMDTIIKDDPSMLPMTNFENKYLECGESIYELTARVVRSTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIV1</accession>
    <name>A0AAD8YIV1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002442</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIV1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="391" mass="43777" checksum="F834E4F1AF9E7AE3" modified="2024-05-29" version="1">MHALWSIIAVLSKLIDRSYNPSFAKMILQSRLLIATLFAPLALAMTPLPIHQSGSRTKLSSFTDHINIHSRRHSLKSSNHCEEIFTTLRGGSDNGGNYNTNPVNSQQPQPPAAQQATTNTAGGGEYADVMAANNDPMYGYRETVEDRIDAWRKQQQHMQQNQSAAEAASAVDEQGRFKLFTTVSKVSVSFFFFILMWRTVHHYELADATFGPTGRRTSKGGFKAFFVRTIVTSPLVVLFLGEMMGAILGISGGGAGQSHSTKKRLKGILNLHKGVELVSMVYNIARLALFPSKYTIREVYIGRTISNFFFLLQCNLYTKLSWDDVSKNTAGDGYVYESYYDDYTPEMENEYASSWQGENDDGYAATAQQSEYYQQNEAADGQQNQQYYPQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJ91</accession>
    <name>A0AAD8YJ91_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002909</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJ91"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="69" mass="8131" checksum="BC275680530EC363" modified="2024-05-29" version="1">MDRVKITDKHDGKVLMKMSVQQMRTQLFDDKDSELAKRLFDILRLENDKIAKIQRADRIKLSKARKGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJY4</accession>
    <name>A0AAD8YJY4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MalT-like TPR region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001944</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJY4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45641:SF19">
        <property type="entry name" value="NEPHROCYSTIN-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45641">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="721" mass="80849" checksum="364F096907262285" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKH7</accession>
    <name>A0AAD8YKH7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002543</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKH7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="319" mass="36822" checksum="665528FED53BA0D9" modified="2024-05-29" version="1">MNCRWRQKQRVSLEYEFYFTPSTLTQTFLCPPSIFLHHVAPAATNLGYTQELWDSNQESSCCKEEWDELNNVQQDAATLLGYNQKKWDNMTMYRLNLRFSVLCFLLGSIFYFKLSFLDLVWMKYVRDYVPESLADEEDDEIWSQWAAEHNAADMLEVRDDYYEQYGLFHMLGVTAFAVMGFSEVYRECSRANLILLAAGLAAMAGAFSSTDQIAAYWSCASVHFFLMSCYNLDSKLFKAGCILECMLSYFLLAGYTGLWIAYADMIASLLWLYCALQEVSAVCEFRSSFGKNGSSTHLEIFIEMMYSLINVPTFKMKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLE8</accession>
    <name>A0AAD8YLE8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000111</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLE8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="123"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="382"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="519"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="661"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="829"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="870"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="527"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="684"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="743"/>
            <end position="761"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="936" mass="102703" checksum="F12B32DD02A9A928" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMD0</accession>
    <name>A0AAD8YMD0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]</fullName>
            <ecNumber evidence="9">1.3.1.88</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_001853</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>5,6-dihydrouridine(16) in tRNA + NAD(+) = uridine(16) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53380"/>
            <dbReference type="Rhea" id="RHEA-COMP:13543"/>
            <dbReference type="Rhea" id="RHEA-COMP:13544"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="12">
            <dbReference type="Rhea" id="RHEA:53382"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>5,6-dihydrouridine(16) in tRNA + NADP(+) = uridine(16) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53376"/>
            <dbReference type="Rhea" id="RHEA-COMP:13543"/>
            <dbReference type="Rhea" id="RHEA-COMP:13544"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:53378"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5,6-dihydrouridine(17) in tRNA + NAD(+) = uridine(17) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53372"/>
            <dbReference type="Rhea" id="RHEA-COMP:13541"/>
            <dbReference type="Rhea" id="RHEA-COMP:13542"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="10">
            <dbReference type="Rhea" id="RHEA:53374"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>5,6-dihydrouridine(17) in tRNA + NADP(+) = uridine(17) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53368"/>
            <dbReference type="Rhea" id="RHEA-COMP:13541"/>
            <dbReference type="Rhea" id="RHEA-COMP:13542"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="13">
            <dbReference type="Rhea" id="RHEA:53370"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the Dus family. Dus1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.88" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMD0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082">
        <property type="entry name" value="TRNA-DIHYDROURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082:SF5">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(16_17) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="14">
        <location>
            <begin position="106"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="DUS-like FMN-binding" evidence="14">
        <location>
            <begin position="202"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1747890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="569" mass="64396" checksum="1156EB8D84A5C431" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMP6</accession>
    <name>A0AAD8YMP6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cleavage and polyadenylation specificity factor subunit 3</fullName>
            <ecNumber evidence="9">3.1.27.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_001137</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.27.-" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMP6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006398">
        <property type="term" value="P:mRNA 3'-end processing by stem-loop binding and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16292">
        <property type="entry name" value="CPSF3-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10890:FF:000001">
        <property type="entry name" value="Cleavage and polyadenylation specificity factor subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021718">
        <property type="entry name" value="CPSF73-100_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050698">
        <property type="entry name" value="MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11203">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11203:SF11">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10996">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11718">
        <property type="entry name" value="CPSF73-100_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16661">
        <property type="entry name" value="Lactamase_B_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01027">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01098">
        <property type="entry name" value="CPSF73-100_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="6">
        <location>
            <begin position="17"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-Casp" evidence="7">
        <location>
            <begin position="253"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term" evidence="8">
        <location>
            <begin position="505"/>
            <end position="751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1749198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="754" mass="83398" checksum="78B60A708699A00F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMV7</accession>
    <name>A0AAD8YMV7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001242</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMV7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45288">
        <property type="entry name" value="THIOREDOXIN FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45288:SF1">
        <property type="entry name" value="THIOREDOXIN FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="105"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1749303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="182" mass="20480" checksum="937E5688781CD48A" modified="2024-05-29" version="1">MLNLLDITFEVRPCFEDTETDYPVPFLVDPNADSTIVGDDDIIGHLLEKYGPSPDLFDRKALWPIEFRAFALATAEIAAELRGNPGRTQQSNARPDNAAMKPIELWGYECSPFVRPVKEKLAELGLPHKVVSCSRGSKNRDAMVERTGRFQVPFIIDENTGIEMFEGPEIVDYLEAVYTTKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YP46</accession>
    <name>A0AAD8YP46_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000746</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YP46"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="161" mass="17010" checksum="57F2D0DEAC23ECA1" modified="2024-05-29" version="1">MSRQQNPYYSDDRSHRSRNSHDPGTSSVVSGTYISGAYDPSMGYGGQQLAVIGDQGSVPPPPPRFNNGQVWAGDDVSELGGRTFESRARSIAGSQMLVPKAKYSWASESVGAQSTVMSRRSLATASMPEPEPTRSAGSATEGRCGHLLPGYSPSLSPTSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPH6</accession>
    <name>A0AAD8YPH6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptide chain release factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_001073</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPH6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003747">
        <property type="term" value="F:translation release factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.20:FF:000004">
        <property type="entry name" value="Peptide chain release factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1660">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050057">
        <property type="entry name" value="Prokaryotic/Mito_RF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43804">
        <property type="entry name" value="LD18447P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43804:SF7">
        <property type="entry name" value="LD18447P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="Release factor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0488">Methylation</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prokaryotic-type class I peptide chain release factors" evidence="6">
        <location>
            <begin position="350"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="405"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="124"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="405"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1749134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="497" mass="54364" checksum="95BF512F85B92FB1" modified="2024-05-29" version="1">MASILSACTAAAFRLASKSCTGRRRTIQQAVTKHPYFLQTCVAPLHHRLAFSTHASIDNDDDEQIYDDGLDQLTDLSLATQNRIRSMKARHDEVLRLLHEGGDPTSLGKEMSTLREMSAYCEKVAEINAERLSLQELLEETEASGDEDSKDMIDEIKDELEQLKVQLQPLSQRMHKSLIPVLNPDDVEDLTSSDVVIDIRAGTGGDEACLFAAEIMAGYEAIAKSGGDGGKSWDIEILSCSTTDLGGVKEASLAVSSRGGGGGGGYGYESFDVASDDAPEDEDMAQKLLQQLGPYGFFQYESGVHRVQRVPVNDNKLQTSAVAVGVLPAIPEGALGNALPPTELKIDVMRASGAGGQHVNTTESAVRITHIPTGIMAYMQEERSQHKNKSKAMRLVAARVHSLRKQQALQERSNARSSLMGGGDRSERVRTYNFPQDRITDHRCKVSVQGVQSWLSDGSMVGKFAPHLYKMERDDRTAALEEELDDSGKNGKKRRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3N5</accession>
    <name>A0AAD9D3N5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/beta hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_016886</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000066">
        <property type="protein sequence ID" value="KAK1732492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3N5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="167"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="62"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1732492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="427" mass="47733" checksum="62E517BD9604C79A" modified="2024-05-29" version="1">MTMSARCRPRHRSLGIFLFMKPASSSLQLLFSSRRRISMKMMSSTSNSRQGRIWTHRPFQVTPSSTTTTTNPSISNCPLPTKTPTPPFENRIHVVYQSAGPVALEQLCQSKQEFYKTQFSSRVVTEDVDRIRKRKLASSSSSSREVNVTIYLPKSDPNNTKLNGICLHVHGGGWIWGDSQYQVAHRCLEMTESMNVAVVSVEYSLASTVCNDNGQIFDPVNEVVTALDWIENIGADELNTKPVYVASGESSGAQLLLLSMLKRRDRADGMPSLTSTWKCLNLVYGFYDISGTPSMREDGNDSSPICGNELICMADMYCDKILHGGNHDEQCKKKIDRQHPSISPMYANLSNLPPALISVGTADPLLDDSLFLASRYSICGNDVETVLYEGGEHGIGHFGLQEEDEMGRRAREYTLQFMKRYLEEHIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4Q6</accession>
    <name>A0AAD9D4Q6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016467</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4Q6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="252" mass="27604" checksum="0C88D615A4BEBFF6" modified="2024-05-29" version="1">MVDSYQTMKASSQVTFPEDDEVGKLVRTLRWEDTFFDEEEGLVAVFDFDYEQIASFRKSAAFAAMLFPPIFILSTLLCAPCLYQQQINWDVYSQHVAITRDGIKFVKDRRKTGCGLSCTDAGKSSKTVPFDKLTDCDITEPAGATCCCIENVLSVVTVDTASSGGGGGDVGPTHELSLAGLKEPQKFKQLVWAMKRAASAKGPMPASAPLSFAPPLQSAMDRGFSNEETNAILRDIRSELIELNANFKNMNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4R7</accession>
    <name>A0AAD9D4R7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015577</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000045">
        <property type="protein sequence ID" value="KAK1733722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4R7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="206"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="225" mass="25843" checksum="182B7A2836DEFFC2" modified="2024-05-29" version="1">MHHIEDLLKKFNINLSKEAHVDNMKADSIESEPNPRPRVRVSFSETSTLNVYENYRDDLHRSNIAYSIQDRDLFNTEATQEADRIKVLIITAPQESRAESIKYLLKNNIVAKEELVGIEHLALDNSNRSEIRKRHSMAVLKKQQEQQQQQQQNQQYPSLRDPTMALGNFARKNSLESRNRARARAALCCEPRRSDTKESAAGNYQSGEYSSSSYGEEITTDQEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D513</accession>
    <name>A0AAD9D513_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_016101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000052">
        <property type="protein sequence ID" value="KAK1733244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D513"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="117" mass="13556" checksum="CBCDA6427880E54F" modified="2024-05-29" version="1">MSRAVICFLLAKHGKRSKDHNDTIADEVASYVFAFFEFYFQFTQDYFRASFHLNVILAPAQSLGGDRLDLDDGLDRVYGQQQRIREVYPFNLKALSTLDKVDDFLAHETQSILTTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5D1</accession>
    <name>A0AAD9D5D1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Vacuolar-sorting receptor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_014934</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endomembrane system</location>
            <topology evidence="10">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5D1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.30.30:FF:000032">
        <property type="entry name" value="Vacuolar-sorting receptor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056858">
        <property type="entry name" value="VSR_TRX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22702">
        <property type="entry name" value="PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22702:SF1">
        <property type="entry name" value="PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25011">
        <property type="entry name" value="VSR_TRX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-0675">Receptor</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0732">Signal</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042045015" evidence="12">
        <location>
            <begin position="22"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="452"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="13">
        <location>
            <begin position="66"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar sorting receptor thioredoxin-like" evidence="14">
        <location>
            <begin position="206"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF25011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1734427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="517" mass="56134" checksum="EB544A28A19C7844" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5Q2</accession>
    <name>A0AAD9D5Q2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase (Family 61)</fullName>
            <ecNumber evidence="2">2.4.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015222</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.-.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1733964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5Q2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007657">
        <property type="entry name" value="Glycosyltransferase_61"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961:SF140">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="428"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="817" mass="93376" checksum="DEB5DC7DA6F67EF5" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6K3</accession>
    <name>A0AAD9D6K3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">UAA transporter family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_014647</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6K3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005459">
        <property type="term" value="F:UDP-galactose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005460">
        <property type="term" value="F:UDP-glucose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778:SF18">
        <property type="entry name" value="SUGAR PHOSPHATE TRANSPORTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08449">
        <property type="entry name" value="UAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1734774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="395" mass="41849" checksum="8ADF85698B944CDC" modified="2024-05-29" version="1">MTQSTEDNAMSFELSARDGASATSEADKAPLLPIHDVPADAASPASSLNVGSSAATNNDTKSRAMQLLFGAGGIYASFLYYGSLQEDVFRYESEDGTKFTHAWYLQVLESLANVIFGTIALIVMGASSNSKNSVGLWWGGTPNLPKKPFVSSGFSQVCSKAFTSLALANGLSFPVATLAKSGKMAPVMLGSLILGGATYGLREYLQVLAIIGGTAILSMSKKKASTSESTPLGAVFILLALVMDGVTGGVQKRLLADMKRVQVTPQPYDLMTYTNLFMMLFALLISFVLGEFTQGIAYCASNPKVFSLIWKFSMCSAIGQSFIFYTVARFDPLVCSTVTTTRKILSVLYSILFKGHSIAGQGWLGLLLAIGGIASEVVHKAMGAGKKKLKSLGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6U0</accession>
    <name>A0AAD9D6U0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014383</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6U0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="47"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="665"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="681"/>
            <end position="704"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="704" mass="79780" checksum="9136F3E46349CB14" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7N1</accession>
    <name>A0AAD9D7N1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Voltage-dependent calcium channel-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_013606</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7N1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005891">
        <property type="term" value="C:voltage-gated calcium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005245">
        <property type="term" value="F:voltage-gated calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051173">
        <property type="entry name" value="Ca_channel_alpha-2/delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10166:SF37">
        <property type="entry name" value="STOLID, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10166">
        <property type="entry name" value="VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042014552" evidence="2">
        <location>
            <begin position="21"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="3">
        <location>
            <begin position="211"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="630"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="632"/>
            <end position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1735900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="715" mass="77816" checksum="9198E881FD09648D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8L2</accession>
    <name>A0AAD9D8L2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dienelactone hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.45</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.45" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8L2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008806">
        <property type="term" value="F:carboxymethylenebutenolidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050261">
        <property type="entry name" value="FrsA_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22946:SF0">
        <property type="entry name" value="DIENELACTONE HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22946">
        <property type="entry name" value="DIENELACTONE HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041980371" evidence="1">
        <location>
            <begin position="25"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="domain" description="Dienelactone hydrolase" evidence="2">
        <location>
            <begin position="69"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="577" mass="62022" checksum="5F623B9A34EC8184" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8Z0</accession>
    <name>A0AAD9D8Z0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Platelet-activating factor acetylhydrolase-like protein</fullName>
            <ecNumber evidence="3">3.1.1.47</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011935</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.47" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8Z0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003847">
        <property type="term" value="F:1-alkyl-2-acetylglycerophosphocholine esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051532">
        <property type="entry name" value="Ester_Hydrolysis_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383:SF32">
        <property type="entry name" value="SGNH-HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383">
        <property type="entry name" value="THIOESTERASE 1/PROTEASE 1/LYSOPHOSPHOLIPASE L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="2">
        <location>
            <begin position="264"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="500" mass="56020" checksum="73F405A7C66672CD" modified="2024-05-29" version="1">MSKWSAVDQEYGDDDAEAVDDLVSSKASSSTLDMDDGNDDEDFPSYYPQPKPQRTCLFYGATVLSFIIIYRTEICLGAALAFCVSIAIKDFSSTKGGRRSKNAFKNAHVFHDYSNINSKYDLTLGSIDHWCLIGDDNNCQCEDPLVPMGKHSSRKWIAQHKENMKVATEAVMKLIDVSNTKEWNDFEGYVPGLDDGWIDGADDDWIYAKGARFGDDYSYLGEDDVFGNDFDPDADYAASYDTGANAGDETGERKMESTGLDVVFIGDSITEQRQGTAHGEHVDDYVSIKEVFDKTFTKDKGGDFDGIAMGIAGDTSPNVLWRLLNGESPFGLEPKVWWVHVGINDLSVKGCSEEVTLLGILRVVEEIQNKCPDAKIVINSILPVRRNEEGLLEHIGKNHEDQALRKKELNMMDSSLSPKRMHADLWPSIVSINEELSKFASKHKGIKFFNADEVFVEEREDAKYLKVDLMDDAVHPNFSGHKKWNNAIKKRLHEILNDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D975</accession>
    <name>A0AAD9D975_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D975"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="60" mass="7013" checksum="395107BD38B4D568" modified="2024-05-29" version="1">MTASSSAQRRHEWPLCWQQLAQQGKRVLMVEAHSIPGGYTTNFYRKGFRFEISTHVMNGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9N0</accession>
    <name>A0AAD9D9N0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_011590</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9N0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="248"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1737818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="356" mass="39461" checksum="1FCB864A1CFCFBC4" modified="2024-05-29" version="1">MTFISGRLVHEDINKLTKKNVISVGCSVHAKENLDILAAVLTTTATKLETLQLDDTATALQNDNFLTALTKNDTIRFLNLRSSGCDDDGAIALATVLRKNSTLQTISLNDNNISDVGAKALAEALKENTAVQKLYLNDNIISEEGAKALADARRGIDGKLQIIVSLRRNKLTDEAFADALKESPTICQRRHVDSNDGREEELAEKSPTTISSPIISEKESAASNKISNVGAGVTAKDTNTWDRLQMNIDNYLAERKLMKQQLDNLSTARHEARDELAAKDAMLRKKDDELLTQRKQSDQYERRVDTLTAEQERMIQQLEDKLSADNALAAGEAAAKDAELKINYEEMLNLRKQNRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9V5</accession>
    <name>A0AAD9D9V5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9V5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19671">
        <property type="entry name" value="UBR-box_UBR4_5_6_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="564"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="669" mass="74175" checksum="EAFE502815E44FF6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DA84</accession>
    <name>A0AAD9DA84_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011059</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DA84"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02257">
        <property type="entry name" value="Peptidase_C19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C19 ubiquitin carboxyl-terminal hydrolase" evidence="2">
        <location>
            <begin position="433"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="566"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="586"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="706" mass="79671" checksum="85F6490118998287" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DA89</accession>
    <name>A0AAD9DA89_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)</fullName>
            <ecNumber evidence="4">5.4.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_011074</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23536"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="5.4.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.2" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DA89"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004614">
        <property type="term" value="F:phosphoglucomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.50:FF:000002">
        <property type="entry name" value="Phosphoglucomutase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000004">
        <property type="entry name" value="Phosphoglucomutase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.120.10">
        <property type="entry name" value="Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.50">
        <property type="entry name" value="Alpha-D-phosphohexomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045244">
        <property type="entry name" value="PGM"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005737">
        <property type="entry name" value="PRK07564.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22573:SF2">
        <property type="entry name" value="PHOSPHOGLUCOMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22573">
        <property type="entry name" value="PHOSPHOHEXOMUTASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24947">
        <property type="entry name" value="PGM1_C_vert_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="Phosphoglucomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="Phosphoglucomutase, first 3 domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041999903" description="phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)" evidence="9">
        <location>
            <begin position="24"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="10">
        <location>
            <begin position="57"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="11">
        <location>
            <begin position="245"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="12">
        <location>
            <begin position="368"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1738405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="643" mass="68513" checksum="48ED76D33B09F0A6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DA95</accession>
    <name>A0AAD9DA95_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_009676</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DA95"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019614">
        <property type="entry name" value="SAM-dep_methyl-trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43042:SF3">
        <property type="entry name" value="RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE YWBD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43042">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10672">
        <property type="entry name" value="Methyltrans_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S-adenosylmethionine-dependent methyltransferase" evidence="4">
        <location>
            <begin position="83"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1739917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="395" mass="43848" checksum="70FAF7A2B3CF40C1" modified="2024-05-29" version="1" fragment="single">HHHHHQTNQVSQGGAISSSTIEHQSSLHHRVAQHNSIHMRLLLLLLSFLLQPQSSNSLGHPALLNSIKSFHQPPSSSVADACRIFHGRGGLHPGADHLTLDYYAPVFLLTSFGVELEENELDSYCSALCETLDANEDDDDISQQHELTIVYQCRGANTTAETRLLCGTIPDPHIVTENNGQDQYLAHLLRGQNHGLFLDMSNGRTWLRNKCQTKDVSSVLNLFSYTCAFSVAALNGGADKVVNIDMSRGALKVGQRNHELNGVSNKASFLSHDIFKTWGKMKRAGPFDCIVVDPPSYQKGSFVAKKDYGKVIRRLPSLLNKDGYALLCLNAPEMNSEFLLEKVKEECGTEMVFVERLENPSTFESAFPERALKVLLFQYQPSDDVSSVATEDFTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAL8</accession>
    <name>A0AAD9DAL8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Holocytochrome c-type synthase</fullName>
            <ecNumber evidence="10">4.4.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_008536</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>holo-[cytochrome c] = apo-[cytochrome c] + heme b</text>
            <dbReference type="Rhea" id="RHEA:22648"/>
            <dbReference type="Rhea" id="RHEA-COMP:10725"/>
            <dbReference type="Rhea" id="RHEA-COMP:10726"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="ChEBI" id="CHEBI:83739"/>
            <dbReference type="EC" id="4.4.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the cytochrome c-type heme lyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.17" evidence="10"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAL8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004408">
        <property type="term" value="F:holocytochrome-c synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000511">
        <property type="entry name" value="Holocyt_c/c1_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12743">
        <property type="entry name" value="CYTOCHROME C1 HEME LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12743:SF8">
        <property type="entry name" value="PROTEIN HRI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01265">
        <property type="entry name" value="Cyto_heme_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00821">
        <property type="entry name" value="CYTO_HEME_LYASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00822">
        <property type="entry name" value="CYTO_HEME_LYASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0349">Heme</keyword>
    <keyword evidence="6 10" id="KW-0408">Iron</keyword>
    <keyword evidence="9 10 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="90"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="447"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1740441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="609" mass="66217" checksum="F6C28037B4EA6C2A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBI6</accession>
    <name>A0AAD9DBI6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fucosyltransferase</fullName>
            <ecNumber evidence="5">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_007730</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Golgi apparatus</location>
            <location evidence="5">Golgi stack membrane</location>
            <topology evidence="5">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the glycosyltransferase 10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBI6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032580">
        <property type="term" value="C:Golgi cisterna membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046920">
        <property type="term" value="F:alpha-(1-&gt;3)-fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11660">
        <property type="entry name" value="Glycosyl transferase family 10, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055270">
        <property type="entry name" value="Glyco_tran_10_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001503">
        <property type="entry name" value="Glyco_trans_10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038577">
        <property type="entry name" value="GT10-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11929">
        <property type="entry name" value="ALPHA- 1,3 -FUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11929:SF194">
        <property type="entry name" value="ALPHA-(1,3)-FUCOSYLTRANSFERASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00852">
        <property type="entry name" value="Glyco_transf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4 5 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042158285" description="Fucosyltransferase" evidence="7">
        <location>
            <begin position="23"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="domain" description="Fucosyltransferase C-terminal" evidence="8">
        <location>
            <begin position="913"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="304"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="935"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="312"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1741252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1106" mass="125622" checksum="B2D6C0159AFC9413" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCD8</accession>
    <name>A0AAD9DCD8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008690</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCD8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011735">
        <property type="entry name" value="WlaTC/HtrL_glycosyltransf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09612">
        <property type="entry name" value="HtrL_YibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="282" mass="32511" checksum="930393F5BD440251" modified="2024-05-29" version="1">MTRKNGVCHADTVSGEFNELSNGRVSGDDADLLALMRVGYKETDSQGYDRIWKYMGSRPAPSFDSVSVVPGQNQSVHKHKQVDQSSPATIVTAYFKIKSKHTRTEYNQWMGNTMSLHDPMVIYTSPDLVPAIKRLRSHALEHTMVIPMELHEMRMPTQYGIQPFWEKQHAMDPEKTIHKSYHLYWIWNEKLEFLRRTIAENPFQSNFFAWVDIGYFRTPKYNHQVMLKQIPSTLEQDQILGLDVRGFGEGEHMGGGFIGGYAAGLMRFHSIFYALLEAHKHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCK7</accession>
    <name>A0AAD9DCK7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008898</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCK7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="234" mass="26131" checksum="B1108A868B7B179C" modified="2024-05-29" version="1" fragment="single">SQSTQQHRNQNQPPAQPNLYAPANTATEEPIEPQLHHHLLIITMPPKVRVKIPIHVLVYSVGFFPAAAYAYHWYKNAPTDEEFEQQLSKNYSQNIQTSREKHVQMTQFLQNIKDPNNTEQQQRMQEVLLGGRGQQKRHYAVDDSIYGTEEGAKLQMEAVDGSGKIIKKRKKKKKRKDKNDKGGSEDAEGATLANDNVTNDDSNVRLKQSVAGVVVAGTLAAGISMFLGGGKRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDI6</accession>
    <name>A0AAD9DDI6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007383</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDI6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56796">
        <property type="entry name" value="Dehydroquinate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="491" mass="51920" checksum="F3AAF81634F93460" modified="2024-05-29" version="1">MASATALQPLRNYIRQNIGHLRATPCLLISSSPPPSISTAIAGTKNPDGLSKDEKQQQQHKQQLKFQQQQNDPKTHAFVQRNIQSIQLEFNLRTVPCTISSAFPTTGSVNEAVSLAKRFGLKEGQFGSGDGLIIGIGSGAAMDLAKAVADSLFGNISSCKDGNNQQEGGSLVLAPSTLGGFMAASSNTPSLLLDTKEEMILPHLTSSWTAALDGHCRQGTVVTMDQQLSLPPLYYPLQPPKRSESLPGPSMAHYAAAMLSILIDVARALDESNTQQPIDAVLLEDIKAVASASASVLKLAAKEANESNSTVQEGDSYATAQQHFLSAIPRLSAVVDQSSHLTHGSSVPQSLANALLPQYFPSCHLVTYLACILPGLCESLATQPASNVEGKVSVVEELTKSIFSCIDDGGKTDDKVQVASLLSWASQITEETAIPTMASLAFGTPDINTLTGSLDSYDALVGSMTGANAGIRASSDDFALMEDVLHRSLNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDP9</accession>
    <name>A0AAD9DDP9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007578</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDP9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="214"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="250"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="426" mass="48850" checksum="4EC98534DA9FBF30" modified="2024-05-29" version="1" fragment="single">MPSARTPKRYAKIPAGSNPASPIDEKSEHDYDIEHDFQAPFCSDECIDTKTSVSAFDGLSIDGKRATYISERTSSKEIKYLHNERFIEDASSVEPSQSNPYHHYIPPLIRLICTTNLVNDQTILRIYRRLCRVDHDSKVDDGGTTLVKLIKLWLVIIGGILITHPFARWMKWEIDDTYSIADFFLYDFTTVLFDMLFFFVVGRMYNSEVDIDKLFPWGIFIALGCIYPSIANDFAFLRHSLSMYEMMCNWPMILFAYVATLLVLAVLLVGGLLRSHYRRMVLISRCIESVVLAVMFILPFASNNNFHLHHWFGMWFLGMQSNAPEWWSRAFQAYCLGSYINGIAVYGRDPILGCNMAFYRSTNANCQYMSCYEAGGGNGTHHYKPFVAPDWRTCNATGVHSNTTETLQLRSLEGHQTSLKFLLQYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DE27</accession>
    <name>A0AAD9DE27_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">50S ribosomal protein L19, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_005489</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial ribosomal protein bL19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DE27"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001857">
        <property type="entry name" value="Ribosomal_bL19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038657">
        <property type="entry name" value="Ribosomal_bL19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15680:SF9">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL19M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15680">
        <property type="entry name" value="RIBOSOMAL PROTEIN L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01245">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00061">
        <property type="entry name" value="RIBOSOMALL19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="16"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="44"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1743892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="262" mass="29802" checksum="6EB11F5D2DA85773" modified="2024-05-29" version="1">MFPSLRIAAQRMNSLSIRSTSTIPSMPSHKKAASPSQIEKAKQLLTSPSLPRSQMNKSRLFPSYRGLPTNEKYDPRQPTTTPEGKTLYPSKARYDTGVAPADMPYLHHIGHDEKPKPKFKNPRKRASKLFNELKLEAVADSKSSKPEVWEVPFKVGDAVELEVLDSGGVQNPQNKRYDKIRGVVLGRENKGLDTGIYLKDVLFGEHVERKVKLHSPMVKSLKVLEEGFVNRGKKKGRRVKRAKLYYLRDRKPEETRVTKIQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFV0</accession>
    <name>A0AAD9DFV0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">General transcription factor IIH subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_003950</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TFB2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFV0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000439">
        <property type="term" value="C:transcription factor TFIIH core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040662">
        <property type="entry name" value="Tfb2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004598">
        <property type="entry name" value="TFIIH_p52/Tfb2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13152:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13152">
        <property type="entry name" value="TFIIH, POLYPEPTIDE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03849">
        <property type="entry name" value="Tfb2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18307">
        <property type="entry name" value="Tfb2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription factor Tfb2 C-terminal" evidence="10">
        <location>
            <begin position="547"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="26"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="40"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF18307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1744659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="622" mass="69034" checksum="0CED0D0874FBEECF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFY4</accession>
    <name>A0AAD9DFY4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFY4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="208"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="239"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="367" mass="40381" checksum="A839AB5EE2509F84" modified="2024-05-29" version="1">MDLFAPPQPVRTRSRQSSVQTVNPLATESSPSTAEVVAGGRSSQRNKKAQDPPSSSPPSSNSKGKSRSSPKTPLDPKAGADAADRKAMSTTNKKYGSSATLVHVPHPSQGSNFDPFATYHKSPTWEMDGLQKSIESAPARMPIARHAMPESNSPQVNEISYTNINASDEEMHAALQLSFEESPEGKVSGYRRTLHGKKPRSLMSSHPQQQQQHQQQQQAGHPFYHHQGHPMMSAPSNQSYMYPPAAMSPPSQQQGYLPPGYPVQWGGSPAAGGYYSMFPNSEDRDHLRMLPPNSVSRTPAKRKAAHQQEEDVNVTTETMDTTCDESFAGPFSPPSAFKRQRMRLKHTKLGLRLLVRRSGLVLPRHEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG72</accession>
    <name>A0AAD9DG72_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Subtilisin inhibitor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_003916</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protease inhibitor I13 (potato type I serine protease inhibitor) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DG72"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009611">
        <property type="term" value="P:response to wounding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.10.10">
        <property type="entry name" value="Trypsin Inhibitor V, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000864">
        <property type="entry name" value="Prot_inh_pot1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036354">
        <property type="entry name" value="Prot_inh_pot1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33091">
        <property type="entry name" value="PROTEIN, PUTATIVE, EXPRESSED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33091:SF29">
        <property type="entry name" value="SUBTILISIN INHIBITOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00280">
        <property type="entry name" value="potato_inhibit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54654">
        <property type="entry name" value="CI-2 family of serine protease inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0722">Serine protease inhibitor</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1745992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="71" mass="7957" checksum="666E45565B859F93" modified="2024-05-29" version="1">MSNTATTSTWPDKILKGMSGEEAQKEIKNVDPSLETHVLPEDAIVTEDYRLDRVRIFVDTQGKVVNQPQKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGX8</accession>
    <name>A0AAD9DGX8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003588</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGX8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="321" mass="33071" checksum="528F0CAA05BB4583" modified="2024-05-29" version="1">MEGGDLPYGSDVSSADKYADRNSDPGVHCSERELLPVLPGGQYTMEGGLYDDGAAAMGAGSGGELGGGPTNAAGGVAAPGMTTGGGGGAGGGGAPTGNESVSLGTATQTHEVRMPMLLSTFKPATGCTNASDFIVRCFVARLRSGITVVKHGRSRWCKSRLRVLHVHSDGRSLSWKPALGEPSSGKRPPKLDLTTCREVRHAWSPDPDNPMFTGTPILRQKCEAANAHKSFALIFPKRTVDITAVTADQCKVLMEGFSALCFRLHVAQKVAGGDGKSGSNGGGVGESGNNNEEQSRATASITASNKSDKGLVPSLGRSEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DH17</accession>
    <name>A0AAD9DH17_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003723</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DH17"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042092105" evidence="2">
        <location>
            <begin position="20"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="199"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="333" mass="34631" checksum="A15B66E2CF5DA416" modified="2024-05-29" version="1">MKSTTTIIPLMSLLMAASARKQLSASRLRRRQLHEALLVDIADPDDKADRALQDETVISMMSEPCLQYSFEGSVELDDPCSPTYAPAASKAPSASPTTSTVPSKAPSTSPTKAPSKAPSASLTTKSPTDVPTDAPSKSPTKEPTPLPTTALVEVVQTPGPTSQPTESPTTTSPTKSPTDAPVDAPSKSPTKEPTPLPTTPLVETAETPGPTPQPTTNPTIRTKQAGDMPIPVPDADCCPGCSCYGFTEIVESSYSSGSGGSGSKSSKGSKSSKSSSGSKSSKSTIKYNEYGSDTGTLRVSEMLAFKDAQNSAHHSRHLSSFFITVAVAINALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHF1</accession>
    <name>A0AAD9DHF1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallophosphoesterase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002626</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHF1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051158">
        <property type="entry name" value="Metallophosphoesterase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31302:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN WITH METALLOPHOSPHOESTERASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31302">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN WITH METALLOPHOSPHOESTERASE DOMAIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="236"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="495" mass="56379" checksum="55587C904FCAE3F6" modified="2024-05-29" version="1">MGNNNIRGGFLRKSHPIVYEILYAACVAIANLIVLFIIYDGRHHLELPRSPIQTLSIVIIAMMAFVSIWRNYIYNRMHHHEYEDRHERKEHGRVTFMQQLFPYWYRISCGLMFFGNCMLPMQILFSSTLLDPKTGDPYQFNIICALCFGFVFTMIGLNILSDTTIFIAQKVVGWTTLYQQLHVLLSSRRWCHFRAPLVFLLSAKIVLGGALIAKEDPIVVQVTVPISHLPDSLENFRIIQLSDVHIGVTIGRTRVKKVVDIVNDLCSGSDDNCNLIALTGDIVDGEPHGLMKAIEPLGNLCPGRDVPKLFVPGNHEHIHFIADQVVTVLSEIGIDSLVNDNIRLHRDETRENQLVVVGFDDLSSRRYRGKEQHAFDGIDAEKDTTILLAHQPNHLKVAERYGVDLMLSVIPRGQFYPGNILAWLFNSRFSGYYPSRGKTAVYVSAGTLFWGHPFGSVLDIMKLQTFVWLGRNRNGVLCNMITFTCYYHFYVYSNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DI83</accession>
    <name>A0AAD9DI83_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome b-c1 complex subunit 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_002074</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UQCRH/QCR6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DI83"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.20:FF:000001">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.20">
        <property type="entry name" value="Ubiquinol-cytochrome C reductase hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003422">
        <property type="entry name" value="Cyt_b-c1_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023184">
        <property type="entry name" value="Ubol_cytC_Rdtase_hinge_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036811">
        <property type="entry name" value="Ubol_cytC_Rdtase_hinge_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15336:SF0">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15336">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 7.8 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02320">
        <property type="entry name" value="UCR_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81531">
        <property type="entry name" value="Non-heme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Ubiquinol-cytochrome C reductase hinge" evidence="10">
        <location>
            <begin position="25"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1746730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="84" mass="9314" checksum="51A7D83311BDEB27" modified="2024-05-29" version="1">MLFDSVGFLRGGEGRAFASEEEIVDHLPALKEACAKHCPAQNKAYEDCKGRIAKLGEGDCEAWYFDVLHCVDHCVAPQAFKKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DI91</accession>
    <name>A0AAD9DI91_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="7">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_000765</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DI91"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF758">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="65"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="427"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="431"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="498"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1748826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="547" mass="61748" checksum="19C167935F7E1F81" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIK0</accession>
    <name>A0AAD9DIK0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000466</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIK0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042145023" evidence="2">
        <location>
            <begin position="26"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="262" mass="30553" checksum="BA4170E94B9FAA84" modified="2024-05-29" version="1">MMIVCIRIWLMWICSLWLCSKPSHSSFLPLLSTNRELKISKTNNNLLRQKMIRSTSNGGIMKNVSSEETSSDMMLRQGGMVAYLPFLSSSILNFITQRTALVALSYILVANTIYLQRRAHLRKMTKRKLLQIRTTREEGVNLGLHVTNIFAWQVFVTSVFPILEPLSRLCGFVSFYYFYPNANGCGIIFEPVSVQHLPIKKRQRSQLRLDWHKFSFNVGQIGRDGYRHPPSIERNLPHLDVPRLQLKHWPWRRKHNKADVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIQ9</accession>
    <name>A0AAD9DIQ9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Zinc ribbon domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_002494</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIQ9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006386">
        <property type="term" value="P:termination of RNA polymerase III transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10509">
        <property type="entry name" value="Zn-ribbon_RPC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012164">
        <property type="entry name" value="Rpa12/Rpb9/Rpc10/TFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034014">
        <property type="entry name" value="Zn_ribbon_RPC11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239:SF12">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00466">
        <property type="entry name" value="ZF_TFIIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS-type" evidence="8">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1747150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="42" mass="4903" checksum="0A2BE436450BF327" modified="2024-05-29" version="1">MAVCPQCSFGEAYFMQMQIRSADEPMSVFYKCVKCSNQWNDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJ56</accession>
    <name>A0AAD9DJ56_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">N-acetylneuraminate 9-O-acetyltransferase</fullName>
            <ecNumber evidence="11">2.3.1.45</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_001396</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PC-esterase family. CASD1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.45" evidence="11"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJ56"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047186">
        <property type="term" value="F:N-acetylneuraminate 9-O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012419">
        <property type="entry name" value="Cas1_AcylTrans_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13533">
        <property type="entry name" value="N-ACETYLNEURAMINATE 9-O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13533:SF1">
        <property type="entry name" value="N-ACETYLNEURAMINATE 9-O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07779">
        <property type="entry name" value="Cas1_AcylT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="274"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="Cas1p 10 TM acyl transferase" evidence="10">
        <location>
            <begin position="72"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="455"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="487"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1747433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="496" mass="57009" checksum="A66BB1F33D3BEB02" modified="2024-05-29" version="1">MKGKAADDGNSKERRRFNPAITIISTMKSIKAWAAQDKNGLKDFMKAQLKVAIILFIANAGNKFEPAYPRNDNHAPTMFWIVNALLAIGTFFTWKWEASKVGRSGSGNPRIICLGREQTEEWKGWMQWAFIFYHYYRVYYVYNEIRVFVSAYVWMTGFGNFLYFDKKADFSIERFVSMIIRINYFPLLLSFFLTVPLELYYVVPLHTTGFVVTMITCWIGYKFETACGMGYWKSRTMAVALSLFAHIIFYETPAVNFLLLFSKEYHFRFQADKYSAWLGMASGLLWGKLGDYMQWAHGYENDQRRRIVSIVQFCGGFGLIAFWYGLFGSIQDKYTYNPVHPYVFIFAVVGWLMIRNCTRYLTECHSTLLEFLGRHTLETYVLQFHLFMTHNVQYIPAVIPGSGADGSAVLKFLNMLLCGSVFLTTAVFARRVTVATQVSVVDLVKNITGTMDTSMTQVVPQQSTERKDSEHEAEETIELTKAESGENGFNSTKVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJ74</accession>
    <name>A0AAD9DJ74_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA-binding protein NOB1</fullName>
            <ecNumber evidence="8">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_001653</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NOB1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJ74"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031981">
        <property type="term" value="C:nuclear lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09876">
        <property type="entry name" value="PIN_Nob1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1010:FF:000020">
        <property type="entry name" value="20S-pre-rRNA D-site endonuclease NOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.210.10">
        <property type="entry name" value="Nin one binding (NOB1), Zn-ribbon-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039907">
        <property type="entry name" value="NOB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036283">
        <property type="entry name" value="NOB1_Zf-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014881">
        <property type="entry name" value="NOB1_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033411">
        <property type="entry name" value="Ribonuclease_PIN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12814">
        <property type="entry name" value="RNA-BINDING PROTEIN NOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12814:SF2">
        <property type="entry name" value="RNA-BINDING PROTEIN NOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17146">
        <property type="entry name" value="PIN_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08772">
        <property type="entry name" value="Zn_ribbon_NOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144206">
        <property type="entry name" value="NOB1 zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribonuclease PIN" evidence="7">
        <location>
            <begin position="17"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Nin one binding (NOB1) Zn-ribbon-like" evidence="6">
        <location>
            <begin position="571"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="149"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="265"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="375"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="443"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="705"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="159"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="381"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="449"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="462"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="722"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="735"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1747690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="735" mass="80413" checksum="5E4F03B14BE6F5FE" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2020-12-02" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6U3T8E5</accession>
    <name>A0A6U3T8E5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_001562</name>
        <name evidence="5" type="ORF">SMAR0320_LOCUS2723</name>
        <name evidence="6" type="ORF">SMAR0320_LOCUS2724</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="HBGZ01003995">
        <property type="protein sequence ID" value="CAD9578087.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="HBGZ01003996">
        <property type="protein sequence ID" value="CAD9578089.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6U3T8E5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140647">
        <property type="term" value="P:P450-containing electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001055">
        <property type="entry name" value="Adrenodoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23426:SF67">
        <property type="entry name" value="2FE-2S FERREDOXIN-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23426">
        <property type="entry name" value="FERREDOXIN/ADRENODOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CAD9578087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CAD9578089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1747599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="184" mass="19555" checksum="676DC80E9F08E965" modified="2020-12-02" version="1">MLSSCFVRVARRSAASAPAATMAARRSMAAAAAPSTVVSSSFNDGPPSVFDKIVKVTIIDPSGARRIIPAMVGQTLYAACDLNGVDLGPSSSGPPQEKVRSTTWTEPLYGEGAASGFDHVLLQGGNEGVEIAEPAHDNEKKMIEEYWDADEIFPESRLASQVEINAKMDGMVVYVPDRIVDDIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2Q2E9</accession>
    <name>A0A7S2Q2E9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phosphoserine transaminase</fullName>
            <ecNumber evidence="4">2.6.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_002825</name>
        <name evidence="11" type="ORF">SMAR0320_LOCUS23025</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.52" evidence="4"/>
    <dbReference type="EMBL" id="HBGZ01032228">
        <property type="protein sequence ID" value="CAD9630746.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S2Q2E9"/>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00197"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004648">
        <property type="term" value="F:O-phospho-L-serine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01494">
        <property type="entry name" value="AAT_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022278">
        <property type="entry name" value="Pser_aminoTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006271">
        <property type="entry name" value="Pser_aminoTfrase_methanosarc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002841">
        <property type="entry name" value="PRK03080.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01365">
        <property type="entry name" value="serC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21152:SF40">
        <property type="entry name" value="ALANINE--GLYOXYLATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21152">
        <property type="entry name" value="AMINOTRANSFERASE CLASS V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000525">
        <property type="entry name" value="SerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 12" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0718">Serine biosynthesis</keyword>
    <keyword evidence="8 12" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CAD9630746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1746218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="415" mass="45046" checksum="A5A06ACCDC9B1D9B" modified="2021-06-02" version="1">MLRFAPRVATRAAAAFQSSHVAAGSAATQALTARWMSAAAPGPKPANPEFSSGPCKKHPGYNISNLPTAVLGRSHRSKLGKERLALAINETKRMLGIPEDYLVGIVPASDTGAYEMAMWNMLGAKDIDICHWESFGKGWFADAVSHLKLRDTVEVTEHTAGYGELPDLTATSKDRDICFTFNGTTSGVRVPDGCDWIADDRTGLTLCDATSAVFAMNMPWEKLDVTTYSWQKVLGGEGAHGMLILSPRAVERLETYTPENRPLPKIFRLAKKGKIEAGIFKGATINTPSMMAVEDYIDALAWAESVGGNDGLIKISNNNLAVVEKFVAENDWIDFLAKDPAVRSNTSVCLTLDLSPEQIKALVALLEKENVALDIGGYRDAPPSIRIWCGATVETADVEALMPWLKWAFDEVKGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRM4</accession>
    <name>A0AAD8XRM4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Hemerythrin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016986</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000073">
        <property type="protein sequence ID" value="KAK1732319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRM4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.520">
        <property type="entry name" value="nmb1532 protein domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="252" mass="28761" checksum="ED7991DC5B4ECFE1" modified="2024-05-29" version="1">MTIEPKEHAVDTETHPADKASKWDIPLESDQWILSHNALRCEINSMIQALGTFICKVDDDNVPQWAINNIKEWWISHVTHVTDHCKSEETVYKPMFSERFKWPAQIDELHDALDSVKDKVQTAIDRLNAEKSNLVAVRDALSTYEATMLKHFEVEETTALPLMRAYFTPEEISPVQRKILEDAPENAMGALIFAMSPDGAKFRSDFMTVRSIPSFVWYLAFKGRLASYKKDVVAKVEAIESGKEPAKKSGWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XS31</accession>
    <name>A0AAD8XS31_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016516</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000057">
        <property type="protein sequence ID" value="KAK1732804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XS31"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="160" mass="17576" checksum="A0EAA71295F3626E" modified="2024-05-29" version="1">MLDRDHVMMRAEFLMVEFVKAVKAPILEMTVVVAESLVIITKVILVMRVALIILRATKTQVILKMEAVKVADHVSIILARLKEVAATATERVTKQLAQKARIAAMGNSLVVDLLAMYILTLATVTLHAATQPILGVTVLEQASLVYHPSLLSLSPKKREI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XS71</accession>
    <name>A0AAD8XS71_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016399</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XS71"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042238760" evidence="2">
        <location>
            <begin position="20"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="270" mass="28627" checksum="55F0675CEE1C784A" modified="2024-05-29" version="1">MHHHAALVGVALLNNLASGFSISPTSISLPTQMTAFPRVGDSSVNNNVLFQNKQQQMFASPLAVRGGALGASTAIGSSSDNGDSVEKDLNLSVGNVLASLWGASGVAYILIKAIVRVLPIALEPFSKADGVVALTNFQLSSYILTCLFFAYAEGYKGFQLKFSPLVVARSFTLQPKSSPIHHLLLAPLYSMGLFHATKKRMIVSWCVTIGVATIVAAVKRMPYPWRNIVDAGVVVGLSWGTISILGGYIISLLTGIAPIGVDPAMPEKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XU69</accession>
    <name>A0AAD8XU69_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Chlorophyll a-b binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_015723</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated. Energy is transferred from the carotenoid and chlorophyll C (or B) to chlorophyll A and the photosynthetic reaction centers where it is used to synthesize ATP and reducing power.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fucoxanthin chlorophyll protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000047">
        <property type="protein sequence ID" value="KAK1733550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XU69"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030076">
        <property type="term" value="C:light-harvesting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="8" id="KW-0157">Chromophore</keyword>
    <keyword evidence="7" id="KW-0437">Light-harvesting polypeptide</keyword>
    <keyword evidence="5" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>4</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1733550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="248" mass="26804" checksum="E43BC7CC12639B75" modified="2024-05-29" version="1">MLHANPPSSSTCCPIPLDRPKDLFNYSTTMMKCTAILALAGSAAAFAPAQQAARMSTAMDATAAQKDFFGLKENVDFSKELGVQAPLGLWDPLGLLKESEDYESFNDLREKEIKHGRVAMLAVVGYLTTAAGIRFPGAEDIPAGMASWGALLETKDGMNVLYQMGAFFVAAEIANREAPWTGVTAEFPGDYRNGKLDFGWDKFSDETKMKKRAIELNNGRAAMMGIWGLVIHEMMGVSILPGGLLPGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUC0</accession>
    <name>A0AAD8XUC0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">NAD-dependent protein lipoamidase sirtuin-4</fullName>
            <ecNumber evidence="12">2.3.1.286</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_015668</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.286" evidence="12"/>
    <dbReference type="EMBL" id="JATAAI010000046">
        <property type="protein sequence ID" value="KAK1733625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUC0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017136">
        <property type="term" value="F:histone deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF10">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="10">
        <location>
            <begin position="64"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="11">
        <location>
            <begin position="393"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="458"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="10">
        <location>
            <begin position="729"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="858"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="941"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="270"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="952"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="974"/>
            <end position="984"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1733625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="984" mass="109206" checksum="77AAD7F6B22D6ACA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUL7</accession>
    <name>A0AAD8XUL7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015694</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000046">
        <property type="protein sequence ID" value="KAK1733651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUL7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="116" mass="13058" checksum="D9551C0400B3A0CE" modified="2024-05-29" version="1">MIPTMEGGLIQRTLTASCHGRMEGLILFFHETAGMECLKNTAFCPTAHNHKASHLRLDLHLVIYHQTKAARQLSSRSPPLKDDDDDDDVKKNDSRFEVDIRCAGNGYDDDTEDERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUR8</accession>
    <name>A0AAD8XUR8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">subtilisin</fullName>
            <ecNumber evidence="6">3.4.21.62</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_015345</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides.</text>
            <dbReference type="EC" id="3.4.21.62"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.62" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1734087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUR8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04842">
        <property type="entry name" value="Peptidases_S8_Kp43_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051048">
        <property type="entry name" value="Peptidase_S8/S53_subtilisin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034058">
        <property type="entry name" value="TagA/B/C/D_pept_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399:SF4">
        <property type="entry name" value="CELL WALL-ASSOCIATED PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399">
        <property type="entry name" value="SUBTILISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="8">
        <location>
            <begin position="152"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="8">
        <location>
            <begin position="273"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1734087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="539" mass="57046" checksum="148D53E5DA66919A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVU1</accession>
    <name>A0AAD8XVU1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014772</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000038">
        <property type="protein sequence ID" value="KAK1734524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVU1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="253" mass="28895" checksum="901135D1F92DD7B7" modified="2024-05-29" version="1">MTLASIAASVAKRAPRYGYHRSSVGTKKKLLNGAHYNPKMNGERTHIGPRGVPPISICVKDMDDNTLLTFGALNDHSAREEILKRHIMDTDDCSYETACDMFNTIAARNMKGYYMVTLPYKIGISSAIFAGVVAFPLVFHLPTIEWFNEWAVTCDIPEARELETPLEVSIWAWNWMEPPLGTISFALLCSQYARSQMNNLGVRPYTRWIKSRRGHALAEAFPMYDEKILAAYSETADLQDWQIKWLEKRRNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVX6</accession>
    <name>A0AAD8XVX6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_014319</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVX6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="3">
        <location>
            <begin position="93"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="912"/>
            <end position="939"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1734859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1156" mass="128651" checksum="CD828F5925F19D8B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW74</accession>
    <name>A0AAD8XW74_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014968</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XW74"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="270" mass="30322" checksum="0D70DBB1DE25F2F7" modified="2024-05-29" version="1" fragment="single">MSGGVFLAGKFDQLQQGKPFSALAAAFNGYCGMLMQSSELQKRREVVASKLRSSLGREVYYLTKIIPYLNDVLGSEQSDDTFYDDNCVDAQRRLRYLLCQFVEVLSSSYDAPVTLFLDDLQWADSASIAAVTQLLCSSGSSTKQKQFFFVGCHREGIIDSAHPVWELVCNAELLGVPFTSLKLDSMAEETLNAMVSETLCALPRLTRTLSNIIYRKTKGNPLFVSQLMLSLNKKNLLFPSLSRRQWEWDNEKIMSQKLPDDVAAFFTQSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XX14</accession>
    <name>A0AAD8XX14_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014146</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XX14"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00136">
        <property type="entry name" value="PDZ_canonical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="236"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="416"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="471" mass="53439" checksum="F40D91EF84D3C0C2" modified="2024-05-29" version="1">MPKVHCIKRRWLEQHKLVACLRQAERIKNGSDQNNDVDDVIMTANIPPSRRGNSSPKDIDRSLAASPGFVRFDDNIDHSSPLLDKTDGIAAITSGSSVVSDNIMPSPIPFNTSTKSAFTRKVSTDTQVMQYHQQERNKLMWKGEEKEMGELLQHAFMHSGQGQISTTNRWSALKLHAIELKSSFIECSEFSKWWADVESYPHQLPRESVSVMKSYCMHQQEMQRYRQSLTVLVPDGTLGISLSSNNDETIVKEVRKSSVLATKVCPGDKIMSIDGEDVSQMDETEISTMLALWHSGCDRKLEIQPSLASCMPFTNPSKNCSQLHSNFKTQLIYEGVKAYITTNRMPFNEVRVLLRQPVSLLSNRVGVKLVEIQEEEANLIWSEAKEHIATWFTSILDRKCQPSYDALPACNAVQPPRNRRRRWGQPNHDILAGGDDQPTRKRRCRWGPPIHTSTKPTELYTHYALTSRKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XY79</accession>
    <name>A0AAD8XY79_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Digeranylgeranylglyceryl phosphate synthase</fullName>
            <ecNumber evidence="6">2.5.1.42</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_013818</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.42" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XY79"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047295">
        <property type="term" value="F:geranylgeranylglycerol-phosphate geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050475">
        <property type="entry name" value="Prenyltransferase_related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42723">
        <property type="entry name" value="CHLOROPHYLL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42723:SF1">
        <property type="entry name" value="CHLOROPHYLL SYNTHASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="301"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="330"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1735655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="377" mass="41308" checksum="E6DED9970B1E4C7B" modified="2024-05-29" version="1">MSIFRYYYIIVALVTLRVEGSFSFNLQYNRISHHTHSSTTASGRVVTSLRRRKRTSLDHQDGRRHVINNNLSIAENCFGQTAKSYIRMMRPVTIIQAVGAFLVGRLVILTSSAASSSLIIKEVPDILTASISIYLSYGAGMAMNDCADVAIDSVHEDKQHRSVASETVSMRNASLFCVALSILSLIFSFCASCTGCNGFPLWSFFNLTVMALYALGLQRIFLVKNLMCGYLAIAPLIGASLLGGGASNLGGDVAGKLYKLALIGFPLQVAREILKDIEDVKVDEGTKKTLPLVIGERKSKWIAYSLVAVVNGTMLLSPYFWTMFKSTPNVYALSVVIGTPMYIWASVLPLSEGQKMLKKSIYVLLLGMITALLNQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYG3</accession>
    <name>A0AAD8XYG3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013396</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000031">
        <property type="protein sequence ID" value="KAK1735949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYG3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="168" mass="18010" checksum="704C52E002F95D68" modified="2024-05-29" version="1">MMASATANNNPLDYPLRLCESVAFILHGILGLCEPFTGCLRSAFQDNGAMPTWFWPLAGSILICVAIINFRGNDVVILMNQAYIAAFHMGGVLYHNSLGHHPASGVGPGMFVFLAFAVACMRAPIWMAFGGLMVCYVFAVGLAKVLVKPKAASDAGRSDESARLLRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZ24</accession>
    <name>A0AAD8XZ24_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1735995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZ24"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="177" mass="19990" checksum="523E216345A70EC0" modified="2024-05-29" version="1">MVQYACCSFMFWCDIVGTLTFIYDLSYINVLRAIPMSIGLEVKDGISILVVIGRTARLARPIRSHVLVEGMHFYVTRNAKLLYLNPSFWLRKLASLQNYRSKSSRNETSLAHASERVLVGSAATNTGNMFSLGDTMRGSDLRNSMVRVTEEQDSEYQPRGRKSAFVSHARKISSLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZ48</accession>
    <name>A0AAD8XZ48_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013264</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZ48"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="371" mass="42327" checksum="C75BE711ECDA5717" modified="2024-05-29" version="1">MEIGNLNKNGSTNDDTLEDDEYEPIISTPSVRSKGEKLGVRVSVNQHKIEALKWISSVLATAVLLCSAKDMFGVRMNREETVAVQDLEGGVVSSIKQQQIANYIKGTAIIRNIHITHHAGTSLCGQMSKVPNEHTPGFACMKKGRNNDTYWPEEAIKASPFDGKHQVGKEVSYNETKEWVSFWRQYYHFVSGEYPDWDKTLHQTNWEYENLVSMIVMRNPLERFLAGGKCGGFQTKIPDDPSNETQDTYWEYANSECADNYALRVLTREPCVQGANTSSECLQGAKDLLNRITFILDQSCLNESVEAFGSALHLNFTKDGFESRLHHWHANLSVRDRFGNDTLYEYVQTRFRRDIELYEWSKNRSIVLCNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZF7</accession>
    <name>A0AAD8XZF7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012867</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZF7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1736267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="111" mass="13002" checksum="E29B8DA0A5353BB3" modified="2024-05-29" version="1">MTRSRLDRLITKYSSPSWNTQANANRLVELLVEHRGLIQIEYNDVTSGLRRLEERDFLGPDERSRIYNTEGRRLDEGNQATDLEYFMALEQKMADMKRSEWQALYSAKGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZT5</accession>
    <name>A0AAD8XZT5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SYO1-like TPR repeats domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_012940</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZT5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052616">
        <property type="entry name" value="SYO1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057990">
        <property type="entry name" value="TPR_SYO1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13347">
        <property type="entry name" value="HEAT REPEAT-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13347:SF1">
        <property type="entry name" value="HEAT REPEAT-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25567">
        <property type="entry name" value="TPR_SYO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SYO1-like TPR repeats" evidence="3">
        <location>
            <begin position="556"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="390"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1736340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="800" mass="87821" checksum="51E032FA9796969E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZU7</accession>
    <name>A0AAD8XZU7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_012268</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZU7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="304"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1736823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="349" mass="39046" checksum="BC4E8597E2A823FB" modified="2024-05-29" version="1">MADVKEQQLREKIASQKASIVNLPTLTSIVDETGLSSPETKARAQLIKELSDNEEQLELLIESERVAAVVRLQDELHPPEDSEDCPICLETIKHVNNATTIRFYCCGGFTCTKCSDERMAKYRAEGFDEMYRGKCPLSCVCKGETLERDESKYVHYLKEAADLGHPRAQRLLALTYERQDNEKMLLHYITLAASQGDSIACCLLGGYFTNADCGLPKSLILAKHYSEKSLEVDSFDSISAYNFSLASLHLGLERYEGVLNIPGHSPIPTILFWARKAQEGESLPIKGGATKLISIIEAKVKGHCANCRKEAECSSFKRCVRCLGAWYCGKECQVQHWRAGHKVDCIKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0N6</accession>
    <name>A0AAD8Y0N6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0N6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005839">
        <property type="term" value="C:proteasome core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="458" mass="50068" checksum="590C05DE186B5001" modified="2024-05-29" version="1">MMPLSICSNRQRRRRRHYDHRLICCCSVALFFLSSITSVCVAKIQIDIPHRRPSVSPLSLSTASLVSLRGGSSSTNNNQQKKQSLSKNSNNEKSPFEYIPITALNNYGQSTQLRHAMEAASRYGTPIIACLCCADEEDSVSNNSDDDGDNSNNEKQRNENCIVICSLQRPRLGIVAPSIPTGASSTNIRRYSTSNTSSKVHPSIQGLVKILATRDDVDNIDATTQSNDNVPTHTLHTAIVSTGIQSDATFLLNQLQRHFSKFWFRYNTLPTNTLAVVKMIQEVLLDCMGYDWSEEVGSAKVSGGVGSAAPSYNENEDESNGSSAAGRPLGLSSFLLSLANDDDSTTFSSPASRPTITLIEANGSSEQYVARAMGVGKQNANGLLAQKWERGMSREQVKDMMQEILQQVAIEHGWLQGDDQDGSSGSATHTDLTITCETLTSRGIDIEFMPLQRVKSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0Z9</accession>
    <name>A0AAD8Y0Z9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Spermidine synthase</fullName>
            <ecNumber evidence="6">2.5.1.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_012396</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.16" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0Z9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004766">
        <property type="term" value="F:spermidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.140.10">
        <property type="entry name" value="Spermidine synthase, tetramerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00198">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001045">
        <property type="entry name" value="Spermi_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035246">
        <property type="entry name" value="Spermidine_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037163">
        <property type="entry name" value="Spermidine_synt_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558:SF11">
        <property type="entry name" value="SPERMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558">
        <property type="entry name" value="SPERMIDINE/SPERMINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17284">
        <property type="entry name" value="Spermine_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01564">
        <property type="entry name" value="Spermine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="2 3 6" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042021057" evidence="4">
        <location>
            <begin position="25"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="PABS" evidence="5">
        <location>
            <begin position="44"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1736951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="366" mass="41464" checksum="AF6A94090A50BBE1" modified="2024-05-29" version="1">MMSMSGKFKLWVIHALLGLECIHAAEPHHDATDSGDTGAQKMKRVIEEEHEIGFIQTLLVHPTPISVQQSDYQTIEVYESDHFGKVFLLDEALQLTERDAPHYNEMLAHVPMMEYLAVQQPDEGGTINALVIGGGDGYVTSELLKYPNVVIDHVDLDKEVINVSKEHFEWSSAWEDERVNLIVGDGAAFVREQVEKKKKYHVIVQDASDPFWYDENGEKIILPSHVLYDMKHFDGIYALLEDSNGVFMFQAETYNIPSNLEEIQTWKKSLEEIGFDGVRYGSIAIPTYSTGQIGFFVAHVSNKDMVCKSDGGVCTMDLSAGLIDWTVVSSQFEKITGTTKYYHPRIHRSAFDLPFWVEEAIYDSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y105</accession>
    <name>A0AAD8Y105_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y105"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="496" mass="56512" checksum="774A157A1D20A902" modified="2024-05-29" version="1">MPAAAAAMNNRSRNNNHHQWTLIAFVAISFCLVIPSFVILGILTNSPANEDKLFDPSTDVHFLIDQPRTEENPDTSRNNKHPTDNALSNNFNTSTNKKRIKRTYNQTSFPGFSKTITTVRCGGHSAPTCTECPNGNGAAWCNGECEWDYKTHECGRSSKLAHIHPDYFRIIQRYAFQPVVTNNGEYVNVVLVRAPFRDGGDEDLYHYYKEEILFLGISSFESFPLRSPNPYSAKYESSYYLNMFPGFLHMMHQPSEHFPPNVKTLLMSQSDFNLEEPYFFGRQQQAQKEEILYDFVYSGGDQDVETDCVGWASYNKNFSFVREALEVMCSDEFNVTGVLVANKNKANTKACTIPSSCDDKIVQTTFLDQRQFFTYLSQARWAFLPQICDASPRVSTQALSMNKPLLMNRNIMGGWKYLLPGVTGEEFNDIHDFRAQLRKILDNTRGKNNPYEPIEFVRENYGNPVAGVRLLEYVKSHWGHRVDLPDGTKFLVPTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1I2</accession>
    <name>A0AAD8Y1I2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011749</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1I2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="248"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="274" mass="31272" checksum="45C4FA92682063D0" modified="2024-05-29" version="1">MISRVNNQRSSSYSNNIMSSCTENVDEGSGEQDNNDAKKQGVLERMKRIRSAPSKIVADTRDDVEFHYTYSVDPLDQHLPDSADDLADQNKSLQASKQSSQRSQQRHRYFIEDEIKRFEVFRTVIQHEDDLLNQRVSWIILAQSFLMAAVFTSEKGDVGEESNGLKYITAGLGITTILITMPSIVAAGRNIELQQRVYFQGISSEERCYELHGHGRDQKMTQDELDNRWKYGHVFPNMAFRGRAALPILNVVIMLAFAQISGWILFLLAIIYGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1N6</accession>
    <name>A0AAD8Y1N6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011839</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1N6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35213:SF5">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35213">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="632"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="223"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="665" mass="69028" checksum="54C2E801A54DB12A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1Z3</accession>
    <name>A0AAD8Y1Z3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rolling stone-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011347</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1Z3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12242:SF48">
        <property type="entry name" value="FAR-17A_AIG1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12242">
        <property type="entry name" value="OS02G0130600 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="291" mass="33088" checksum="D0E9387342746E3D" modified="2024-05-29" version="1">MGCFATIKHELFHASMYDLSVPTDSSEITAVAATNKMMNIDETFAPRPHLFFVGVKLVLAVWLLVTMVISILENEPYYGFWFAYLSSWVMIFTVMYAICSFISAALLAYRRPLERRKTELTGKIGMLLKITWTLFAVTFPAALVVTLLFWFLVFDGTLKYTSFMLHGISWIIVGIDGILINRIPLRIKQFIFLETFSILYLVWSILHSALNVGNPWNNNEGENQPIYDTVDWENGTGFAIGLAVVLLFAGLPIIFMLCRALSLSLPMRCRNNDVCEAFNDEESLEMPTRES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y318</accession>
    <name>A0AAD8Y318_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010759</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y318"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="118" mass="13602" checksum="8C5DFB82ABE1DD1F" modified="2024-05-29" version="1">MKNKQQKGKEWPEKSTEPSLPSHHHRNVHSVPPSIHRSRSLPPRFVCNKWGSEETRKSYKCLCSLANNTECKRCISSSTLNALDRYSIGKMRNPKWRDWWGNFLELSSDGDASATDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y445</accession>
    <name>A0AAD8Y445_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Kringle domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_010739</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y445"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004175">
        <property type="term" value="F:endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005102">
        <property type="term" value="F:signaling receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00016">
        <property type="entry name" value="ALP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00108">
        <property type="entry name" value="KR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.20.10">
        <property type="entry name" value="Plasminogen Kringle 4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000001">
        <property type="entry name" value="Kringle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013806">
        <property type="entry name" value="Kringle-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018056">
        <property type="entry name" value="Kringle_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038178">
        <property type="entry name" value="Kringle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050759">
        <property type="entry name" value="Serine_protease_kringle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24261:SF7">
        <property type="entry name" value="KRINGLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24261">
        <property type="entry name" value="PLASMINOGEN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00051">
        <property type="entry name" value="Kringle"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00018">
        <property type="entry name" value="KRINGLE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00130">
        <property type="entry name" value="KR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57440">
        <property type="entry name" value="Kringle-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00021">
        <property type="entry name" value="KRINGLE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50070">
        <property type="entry name" value="KRINGLE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0420">Kringle</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041974139" evidence="4">
        <location>
            <begin position="21"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="Kringle" evidence="5">
        <location>
            <begin position="42"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Kringle" evidence="5">
        <location>
            <begin position="451"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="128"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1738709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="532" mass="57394" checksum="61E3862E6ED25EFF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4G7</accession>
    <name>A0AAD8Y4G7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010022</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4G7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="421" mass="46544" checksum="161DE5106723D0CF" modified="2024-05-29" version="1">MRFLLKSTTTASRAAASAARDANKLLSKNNAHNAITERATNNITGKAWGQHCSPDCGCVLRFEMQLSNDRVSPALSTTETVAAATYHAKRVMVTKAKHSSDNDENRSSSSSSPSSTNLKPLFTSELSSKSQRPILTSCTCTTLHELAQQVVNHLPGRTLQQLRNDTELGVVGARSSMAFRHTVLRENVLPALAEKEAQSWKKFGEMSSKEQQQQQNEDGKNSSGGGIHEMNSTQQHGHCFDLVEDSFLSMIHEREMSPRKDDKVHAFSPTMGGYFRMYSPSGRQQKQRHLPTQHSLDEDDIAAEYATMRRNDSLASQSGGDWLQKSPSSYFLFGDESSNSKSSYSDGILSLFIDYAKESIFGRDGNATAATSATVENGARPSNYLQLLDMYGDTHSDHGEKEEEPYDDWLDYVDTQSQGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4J2</accession>
    <name>A0AAD8Y4J2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxalate:formate antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4J2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF317">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="390"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="428"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="460"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="497"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="536"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="620"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="662" mass="69564" checksum="692109C8BC21F0EB" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y649</accession>
    <name>A0AAD8Y649_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF285 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009506</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y649"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005046">
        <property type="entry name" value="DUF285"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011889">
        <property type="entry name" value="Liste_lipo_26"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02167">
        <property type="entry name" value="Liste_lipo_26"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03382">
        <property type="entry name" value="DUF285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042054396" evidence="2">
        <location>
            <begin position="29"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="687"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="369"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="692"/>
            <end position="704"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="768" mass="82946" checksum="8BB31DF83802CEF3" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y662</accession>
    <name>A0AAD8Y662_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008488</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y662"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042160659" evidence="1">
        <location>
            <begin position="23"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="281" mass="31097" checksum="BEACE1BE2CE9FD11" modified="2024-05-29" version="1">MLVSKPALAFTILTAVAKTVVSFVPSPSQPPAPATATTTLSAVPEGWKGGFKDTHPDFCYQVVQPDLSDLPIMGNLENIGKNHPHAEDLLAPVLLADISRIGYDDDGRIWSIICPQRGRFIPGLGTVFIEVTVNGVRGWVDEPTHSGYADLGVVGKLWIEADENPVVEFISNILDDMHFPFSKEHSAKVRAFQVGKPYEEFWPMTNGTDPAFYHPQFAQHWEEAFSVYNLEVEVGKQIMTGEKLVDDFNAMIIELFNSLSGNTFAPGQRFDGFDVSAARWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6A0</accession>
    <name>A0AAD8Y6A0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein YIPF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_010014</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Golgi apparatus membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the YIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6A0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048280">
        <property type="term" value="P:vesicle fusion with Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045231">
        <property type="entry name" value="Yip1/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006977">
        <property type="entry name" value="Yip1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21236">
        <property type="entry name" value="GOLGI MEMBRANE PROTEIN YIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21236:SF2">
        <property type="entry name" value="PROTEIN YIPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04893">
        <property type="entry name" value="Yip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="300"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Yip1" evidence="8">
        <location>
            <begin position="179"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="90"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="112"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1739471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="318" mass="33581" checksum="1CE3620C0CAC12E5" modified="2024-05-29" version="1">MGTTTSSTANAGYYGNTSNATTASSTMSGGGGMPMMTSGGSINTNTTNPMMMGNQSTQPAAAASTSYNNDGNMMMMSGAMGSGPIGGGTAPTTTTTSSTPAPHIFDPNAAKQQQQQQQQQENNNNNNMTSIDNNNDEDYENEPPLLEELGVNFPHIYSKSRAVLFPIGKHAKSLEAGLIEDDADLAGPLAFALGLGGELVLVGKMHFGYVYGFGLSGCLAMTLLLNLLNPNGAVSMWTVVSILGYALLPVNLLAGINILYRVHKMNVVGMALAVLIILWCTAASTRLFERGCQMRDQRFLVAYPAALLYSAFVMITIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7H9</accession>
    <name>A0AAD8Y7H9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_008468</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
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            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
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        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
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                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
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        </citation>
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        <source>
            <strain evidence="4">R05AC</strain>
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    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="AlphaFoldDB" id="A0AAD8Y7H9"/>
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        <property type="entry name" value="FORMIN-J"/>
        <property type="match status" value="1"/>
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    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
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    <feature type="region of interest" description="Disordered" evidence="2">
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        <source>
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        <source>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
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                <person name="Topel M."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
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        <property type="entry name" value="Neuro_actylchol_rec"/>
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        <property type="entry name" value="Neurotrans-gated_channel_TM"/>
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    </dbReference>
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        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
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            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
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        <source>
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        <source>
            <dbReference type="Pfam" id="PF02931"/>
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    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF02932"/>
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        <source>
            <dbReference type="EMBL" id="KAK1741908.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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    </dbReference>
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    <dbReference type="PANTHER" id="PTHR45011:SF1">
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    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="4"/>
    </dbReference>
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        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="15"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1741573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="454" mass="51061" checksum="6BD821291D710B07" modified="2024-05-29" version="1">MSKDFESAAADMMCCAACGIKANDDIKLKKCTACHLVKYCGVNCQREHRPQHKRACKKRVAELQDEILFRQPESTHKGDCPICCLPIPINSTNRAENASVMSCCCKMICNGCACADQRRKGKLSECVCPFCRKPMTFKYEEIEMEYERRAEANDPVAMRQLGIRRLEKGDYKSAFDYWTKGAELGDAASHYELSVMYNRGEGVEKDLKKEARHLKEAAIAGNPSARHNLGCAECENVRFDRAVKHWIIAANLGYDKSMMMREIEQSLQQRCPFCRHPAPKTEAEIDKIMMKRVEANDPAAICAVGMNRYHGGESKSALEYWGKAAKLGDAQAHYQLSTTYWEGKGVEKDTKKAIYHSEEAAIGGHLFARHNLGCIEDNNGRKDRAVKHYIIAASLGFDASLEALMKHYKRGRVTKENFAAVLRAHQAAADATKSPQREIGEACVRRLRRENACK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9N3</accession>
    <name>A0AAD8Y9N3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_007809</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9N3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02257">
        <property type="entry name" value="Peptidase_C19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF687">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="8">
        <location>
            <begin position="721"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="54"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="130"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="312"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="576"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="844"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="167"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="182"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="344"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="358"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="388"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="447"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="482"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="517"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1741331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1081" mass="121564" checksum="36BBAEFE87FB3906" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2024-10-02" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9Q5</accession>
    <name>A0AAD8Y9Q5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_007700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1742127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="8" mass="934" checksum="ECBDC2C721FB5446" modified="2024-05-29" version="1">MNYHLVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9T4</accession>
    <name>A0AAD8Y9T4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_006984</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. BUD32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9T4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000408">
        <property type="term" value="C:EKC/KEOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070525">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12209:SF0">
        <property type="entry name" value="EKC_KEOPS COMPLEX SUBUNIT TP53RK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12209">
        <property type="entry name" value="NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="29"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="56"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="207"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="325"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="91"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="325"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1742419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="406" mass="43948" checksum="B1A0BF9161DF5A23" modified="2024-05-29" version="1">MVMSSSSTTITEPTAWYGPPPPPELTDNAASLELLSQGAEARVWLATIDISGAISKADGSTKSSSGGSKRSVHVGSGINVPQLSSLAQHPSPLSDESSSSSSSSQSVKVIVKERFPKKYRHPALDMSLTKSRTKGEARSLIRCKRAEVACPKVLAIANWSNLKDNDGNVHKKSETTKAGNVCTTSSCLFIEHVQGCTVRQYFEQRLESTATQDSPSSKRQRLEEEGDDSNLLEFKQQQDRVTTVIDSHTLCVAYNIGTLVGKMHAAGVVHGDLTTSNIMIQNPPPSTKDITNQETEERSWEADLVLIDFGLATSTNSTIVTTAAAASSNDASNNSKKPHKQQHSAEEKAVDLYVLERAFLSTHPESEPLVEEVLKGYREFFEGMGSNNDGCTEGRMGMLPRQFSIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YB48</accession>
    <name>A0AAD8YB48_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Methionine-tRNA ligase</fullName>
            <ecNumber evidence="6">6.1.1.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_006904</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YB48"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02799">
        <property type="entry name" value="tRNA_bind_EMAP-II_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000225">
        <property type="entry name" value="tyrosine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051270">
        <property type="entry name" value="Tyrosine-tRNA_ligase_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586:SF33">
        <property type="entry name" value="AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586">
        <property type="entry name" value="TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="5">
        <location>
            <begin position="314"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="251"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="251"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="274"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1742339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="478" mass="49338" checksum="8327DACC4CEAF1AE" modified="2024-05-29" version="1">MEAQSALVTLTVSAPILASDPLLALVASIAPPYQTKVAIIKKGSDLSLSIGADSSASVITHRNAILRSLCGLGLHNALDTIGSSPLCFLGGHSATSFAGASPTSAIAMAGISSWMSVADSTRQGTADDASVLIGQLNDYLSSRSFLVPSSTPTVADFDLYLAIVGKLSGEALETSVNGYNNTRRWLEQCGATLDELKIVAAKNAAYSKVPAATIPKGLNPKPRPLPLFFYGEEDESVVAAAAAATSAATKAGGAKPGKAAAATSNDGGGGGLTDEEKKAAADKKAAKNAAKAAKKKDNPKKGGGGGAAAAAELNISALDIRVGKIIKAWEHETADKLYCEEIDVGEDKPRQIASGLRPFYKLDEMQNRDVLVLCNLKPMNLVGFPSHGMVLCASNADHTAVEFAVPPEGAKIGERVTFEGFDGEPEAQNKVAKKKIFQALAPDLKTDENGMVNWKGAKSVTSAGQCKAVNGMANAQVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YB86</accession>
    <name>A0AAD8YB86_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosome-associated GTPase, OBG family</fullName>
            <ecNumber evidence="6">3.6.5.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_005880</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YB86"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01898">
        <property type="entry name" value="Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.210.12">
        <property type="entry name" value="GTP1/OBG domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006074">
        <property type="entry name" value="GTP1-OBG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006169">
        <property type="entry name" value="GTP1_OBG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036726">
        <property type="entry name" value="GTP1_OBG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045086">
        <property type="entry name" value="OBG_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702">
        <property type="entry name" value="DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702:SF31">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01018">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82051">
        <property type="entry name" value="Obg GTP-binding protein N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00905">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51883">
        <property type="entry name" value="OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Obg" evidence="5">
        <location>
            <begin position="95"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="OBG-type G" evidence="4">
        <location>
            <begin position="418"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="200"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="200"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="230"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1743259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="631" mass="70098" checksum="1525E7FF0C5B72CA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBJ7</accession>
    <name>A0AAD8YBJ7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein arginine N-methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.319</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006856</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.319" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBJ7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035242">
        <property type="term" value="F:protein-arginine omega-N asymmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035075">
        <property type="entry name" value="PRMT5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006:SF53">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05185">
        <property type="entry name" value="PRMT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041977118" evidence="2">
        <location>
            <begin position="26"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="PRMT5 arginine-N-methyltransferase" evidence="3">
        <location>
            <begin position="97"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1742291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="425" mass="46288" checksum="E69C37C1E30B96E7" modified="2024-05-29" version="1">MMMSTSRALLISFLAYASIYSCSHGFSLEKPTSRRAALETLTITPFVTTFLPSPQDVAHAADDIDSSSSLPKTTPISAQWNAIDGLNSEDKKIVSFDKSAYQAMMRDQSRTPLFEQAIVNRLKAAEPDSQIVLDLGTGPFALFAVIAAKNGAKHVYAIEASKEAAATARETIEKLGYGDKITILEGFSTDITLPEKADFAVAEIVGSVASEEGAYATIYDAHKRLLKSPNEASSWIPSRIQTYAAPASYTLQNLFLPPAFDWTKLQGEPVRFNCRDEGLQLVSNPVLIEDISFADIITKGGSQQKQVTFTVDGERVEKNKAAFLEEFKRGNPREAEGLSVTTANSISGIALWPRLLLDDNVEVNSRHFPDGGHQKSHWQTVLPIMSEIPVPVKGGDEVSVTFDFTVPTEVTTPSSYKISGSVVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YC49</accession>
    <name>A0AAD8YC49_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_006149</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17744">
        <property type="entry name" value="BRCT_MDC1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051579">
        <property type="entry name" value="DDR_Transcriptional_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23196">
        <property type="entry name" value="PAX TRANSCRIPTION ACTIVATION DOMAIN INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23196:SF1">
        <property type="entry name" value="PAX-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16770">
        <property type="entry name" value="RTT107_BRCT_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="6">
        <location>
            <begin position="666"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="79"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="160"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="310"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="883"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="968"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1394"/>
            <end position="1421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="327"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="378"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="393"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="438"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="456"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="481"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="497"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="520"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="588"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="968"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1743528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1431" mass="158644" checksum="1C6683AF60AB2B07" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCB0</accession>
    <name>A0AAD8YCB0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCB0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="158" mass="16298" checksum="7BC83CFAD5B9C5EC" modified="2024-05-29" version="1">MDGKRTADSNERPTAGDESNEETPWQTGIRRRRHNSRSSNSEEQRQQHSTNTTPPPRRHNGVNNNSHGGHGNLNNSGFGIGGGGGAAIGVGGPCGGGGVAIGNQSSAAFGIGGGAPSTPYKAPSSAGKDLVPVPLISCNSRDRWEHVIYTIAIIESSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCI9</accession>
    <name>A0AAD8YCI9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005513</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCI9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="538" mass="60310" checksum="859AE2A135D978F6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCL0</accession>
    <name>A0AAD8YCL0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3172 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCL0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021511">
        <property type="entry name" value="DUF3172"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11371">
        <property type="entry name" value="DUF3172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="339" mass="37831" checksum="CA666420CD12F776" modified="2024-05-29" version="1">MTSLRRSSHQRRIGIVASLFTSCGFIVLCNSATPCLGFSATSTFSSCRNVHLHYAKRSQHKLATTKLSVRRRRDDYDDEDDWDDYFDEDDDDYDDYDDSPPPRRRRRPNNIDNLGTPPLTGSSNDDTSLDIPSSFGRGDTGWRMPSSVSAALLAGVFVLGIGTGVTVDSQINTNPKDLASRDAVDKNAPNPTLCTTYGASAMAFDQRVFVSFNPFNVYVAQADVKPACVLRQSNVVPVLKERKLLNDNEIRGCKMNMNTWAFVGDLNDQPQLSCVYKSEDAQNEFLEDPKRGIGEDYLDDDVSKMRKETKKMVKDNLTESQKKKIMESQMGEKSASGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD41</accession>
    <name>A0AAD8YD41_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">SET domain-containing protein</fullName>
            <ecNumber evidence="10">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_006683</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="10"/>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1743086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD41"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050777">
        <property type="entry name" value="SET2_Histone-Lys_MeTrsfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22884">
        <property type="entry name" value="SET DOMAIN PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="9">
        <location>
            <begin position="705"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="240"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="251"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="273"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="287"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="353"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1743086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="862" mass="95146" checksum="02D653E9B2ABE2F3" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDS7</accession>
    <name>A0AAD8YDS7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">NFX1-type zinc finger-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_005525</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031380">
        <property type="term" value="C:nuclear RNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002376">
        <property type="term" value="P:immune system process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031048">
        <property type="term" value="P:regulatory ncRNA-mediated heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17936">
        <property type="entry name" value="EEXXEc_NFX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06008">
        <property type="entry name" value="NF-X1-zinc-finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046439">
        <property type="entry name" value="ZF_RZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000967">
        <property type="entry name" value="Znf_NFX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF341">
        <property type="entry name" value="NFX1-TYPE ZINC FINGER-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20173">
        <property type="entry name" value="ZnF_RZ-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00438">
        <property type="entry name" value="ZnF_NFX"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51981">
        <property type="entry name" value="ZF_RZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0391">Immunity</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RZ-type" evidence="8">
        <location>
            <begin position="1559"/>
            <end position="1640"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1743928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1640" mass="184961" checksum="64D62F88EF48B283" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFK8</accession>
    <name>A0AAD8YFK8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cGMP-dependent protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">QTG54_003553</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.12"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.12" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFK8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030553">
        <property type="term" value="F:cGMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004692">
        <property type="term" value="F:cGMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000048">
        <property type="entry name" value="Protein kinase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF143">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00103">
        <property type="entry name" value="CAMPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0140">cGMP</keyword>
    <keyword evidence="10" id="KW-0142">cGMP-binding</keyword>
    <keyword evidence="8 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="15">
        <location>
            <begin position="138"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="15">
        <location>
            <begin position="256"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="515"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="16">
        <location>
            <begin position="776"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="544"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1745629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="834" mass="93344" checksum="0889EA20B11A1444" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YG18</accession>
    <name>A0AAD8YG18_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004928</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YG18"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="22"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="95"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="22"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="38"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="66"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="151" mass="16820" checksum="BAE113E5214491CC" modified="2024-05-29" version="1">MTYKPPSDPDKAAKKLAAIEARIQKKNDKKKAKEEKKAKKNSGKKDGIKKKNILKKPSMPSLKKKVSPDGAKKESKKDKPNDGEPKGLKKIDLFGKDAKAKNAVLEEEKAQLEQKTSTLEQKTSALERQLGSMSMKSQQAKQMIQQAMMVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHS6</accession>
    <name>A0AAD8YHS6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003629</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHS6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="101" mass="11170" checksum="C687F9FA4F42579C" modified="2024-05-29" version="1">MIVWLGVWRAATKYRPKKNKSSFTLDQALLRTDDAFKKNNFGILDALHSSIGEGEGVYPCAALLNHSCAPNAILRYKLDSGDNGGKEERSTIQLPSTLFAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHZ4</accession>
    <name>A0AAD8YHZ4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002233</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHZ4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="64" mass="7171" checksum="05814BA76E93BE47" modified="2024-05-29" version="1">MESEEKDTEESNNESGKVAVVLGAGNQSMLTIIDVLDNVLRHRRPVIVKHHPLRPGWLLPMLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIF1</accession>
    <name>A0AAD8YIF1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003594</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIF1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="373"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="413" mass="46684" checksum="192989BFC7816172" modified="2024-05-29" version="1">MVSIRHHRITPPASFRKSGWKGQPTAVSKTIISRIKASLPFDSILDELCEEDRAEAETKGKNRALKVFVGDGRERIFRNCLLTKQIKQYYDSRQCEVLDFVDIPLSLASRLSDDDLGAILVCIDAKHKLKQLKLTHCTNVVGHGLEPLRGSTVVEKLDLGLVRQFEAPYLRRAPGGSIYEFLFDDAKLSEGPVCAIIDSIYRRETDSLDRLQYPHKWSVNLSEPDVLVPIYDNNVLRSERVKQLVDEHNIIVNKFACCLYFGYEDEKDLCSSLEDDESLGSALVDVCISCKDASFTVCSNCNDIVCYECCDADKCDDCDIIHCPRCRDHSLEKVTWCEAAGYGSDCSPRCSSCRLKSCRNGTNACTECRSEVFDELRDECDTKQVQIDSQNDEMERLRSIIEELTIQANRVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIL8</accession>
    <name>A0AAD8YIL8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_003280</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIL8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050547">
        <property type="entry name" value="DEAD_box_RNA_helicases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47963:SF8">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47963">
        <property type="entry name" value="DEAD-BOX ATP-DEPENDENT RNA HELICASE 47, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042031573" description="RNA helicase" evidence="7">
        <location>
            <begin position="22"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="domain" description="SAP" evidence="8">
        <location>
            <begin position="62"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="168"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="430"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="228"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1746673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="775" mass="85638" checksum="880F5A1EE0C9AE96" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIT6</accession>
    <name>A0AAD8YIT6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">2OG-Fe(II) oxygenase superfamily protein</fullName>
            <ecNumber evidence="6">1.14.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_001332</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIT6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031543">
        <property type="term" value="F:peptidyl-proline dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071456">
        <property type="term" value="P:cellular response to hypoxia"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051559">
        <property type="entry name" value="HIF_prolyl_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12907">
        <property type="entry name" value="EGL NINE HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12907:SF26">
        <property type="entry name" value="HIF PROLYL HYDROXYLASE, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0847">Vitamin C</keyword>
    <feature type="domain" description="Prolyl 4-hydroxylase alpha subunit" evidence="5">
        <location>
            <begin position="10"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1747369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="231" mass="25339" checksum="7C446418A11A09AD" modified="2024-05-29" version="1">MRAEALSLMPQMVPSQSTRWDEETQSVIPYEKKGVLSMQIEGGTAGYAASPRLVEYIVSLTNNLSRKLNQVLPDAYHLATEEQTNKLAVCLGDGSYYDKHIDNLGGSSDAGDQRKLTALIYLQPPNSHDGQPPYPNEKVEDDPRGGYFRAYDVPEVGDVTCIAPSGDRLVVFWSDSLVHDVSPSFAPSEDDKRFALTTWLVADKKTGEIKGTDLEVSARHFDSGENSIGKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIW1</accession>
    <name>A0AAD8YIW1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002912</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIW1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041951383" evidence="1">
        <location>
            <begin position="26"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="370" mass="41568" checksum="36C512C3F90D4D0B" modified="2024-05-29" version="1">MAKPLLLSLALTTLQLHVFVTNGFSASTIQKRSGRNSFLQKHEQPHSYKRTPKHNILSPDELHNLAISLSKRKPGSNGFNRGWIQYRTAALDSIRYHLYTNGLPHPAEKAKFEELFFNLGVAADRGKMPSFANAGARSAYAVEFFCRAKNLADLFADTFNSHYEFPEYWLEGLRGSPILGSSDGGAYSVVSLGGGPGFDYVSSAVATSFCSYMESLRDQEETGSLSSSSLKLHATILDYEEGWGDLVHAMVHSTQTILERSTPTLSCDWGGTLFVLSEVHPRLWPEFYELLQDENCNMEEVGFNKRGRQMLLRKSSSDVITTSQSTKNSPALSEKDRKLLEKFIELRKFHERKIDAGWQRQEPKIRGAKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJ28</accession>
    <name>A0AAD8YJ28_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002577</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJ28"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="168" mass="18675" checksum="AB67E001C3476632" modified="2024-05-29" version="1">MRMTIGQQTKTLSSGEDEHKERLEGKMSTKFSAAAGRLFDYPAILCSSTFSEEDTRSYDPLAAAPRLHQQQQVHTGLDGSRKRSNPPNTAAGCSILDHIEMGNYAHGHVTATSTDEKRDDDNICEDDEGICDEKYVYEEEQNTMSGCCGGSELDSFGSVFKFMQFHEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YK67</accession>
    <name>A0AAD8YK67_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cytochrome-b5 reductase</fullName>
            <ecNumber evidence="2">1.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_001476</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.2.2" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YK67"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090524">
        <property type="term" value="F:cytochrome-b5 reductase activity, acting on NADH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF171">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavoprotein pyridine nucleotide cytochrome reductase-like FAD-binding" evidence="8">
        <location>
            <begin position="109"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Oxidoreductase FAD/NAD(P)-binding" evidence="7">
        <location>
            <begin position="177"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601834-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1747513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="329" mass="36145" checksum="98059AEF44A6EF01" modified="2024-05-29" version="1">MLFSSRLSNHQARKKYIFFFLQLGGVHQAVARSSTASSCQTTKMGVSSYPLLEKWQQSHDSWLLRFGLPTDQKFLGTDPRLPTCISVHHDSSLLDKDKDKDNNKVGLLKKSYSPISHPATERTFDLLVKAYTPVPGGGVGDAICNLRVGQSLVGKLKAERLVHGSPLIGKRWNRIGLVAGGTGIAPLIQLARIILDDPADDTKVYLLSINRNEHDILMRKEIDQLAKDHPNRLYVSYSLTGKNIRSDWEGYIGRGSVDMAKNALPPPSSSDGKTTMIFVCGTDGFRDMWAGPIARAPPLPDGSKGPKIQGDLLGVLKEAGYEASDVFKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YK69</accession>
    <name>A0AAD8YK69_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_002363</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YK69"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="469"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1747019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="705" mass="80199" checksum="502AD0823A23C636" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YL85</accession>
    <name>A0AAD8YL85_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sel1-like repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_000007</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YL85"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="7">
        <location>
            <begin position="18"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="83"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="363"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="435"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1748068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="584" mass="66031" checksum="4549F47D8BC58E5E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLI5</accession>
    <name>A0AAD8YLI5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Tocopherol polyprenyltransferase</fullName>
            <ecNumber evidence="8">2.5.1.115</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_000778</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UbiA prenyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.115" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLI5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010176">
        <property type="term" value="F:homogentisate phytyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43009:SF7">
        <property type="entry name" value="HOMOGENTISATE GERANYLGERANYLTRANSFERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43009">
        <property type="entry name" value="HOMOGENTISATE SOLANESYLTRANSFERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="138"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1748839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="235" mass="25317" checksum="369FF1108CD386A1" modified="2024-05-29" version="1">MNLYITGLNQITDVEIDKINKPYLPIAKGDLKKSTAIGVVLAAVVVSLIMSVCNPVLSTSGLQVALWGSFVLGTVYSLPPFRLKRHPLLAAFCIVAVRGTIINAGFYSHALSAAFSSTKEAAAGFGVLHCLLNDWKCAFSSLFFGVFGIVIALMKDVPDADGDRIFDIKSFTVRIGQKRVFRTMKNLLVALFGVSGGALMKWATMSPTLGATTRRGLTGLGACWLDTLHTKKQKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLZ2</accession>
    <name>A0AAD8YLZ2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RMD1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_001912</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RMD1/sif2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLZ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003734">
        <property type="entry name" value="DUF155"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051624">
        <property type="entry name" value="RMD1/Sad1-interacting"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255:SF6">
        <property type="entry name" value="PROTEIN RETARDED ROOT GROWTH-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255">
        <property type="entry name" value="REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02582">
        <property type="entry name" value="DUF155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF155" evidence="3">
        <location>
            <begin position="413"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="158"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1747949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="628" mass="70732" checksum="E922DCA450434AC7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YM67</accession>
    <name>A0AAD8YM67_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000882</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YM67"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042233930" evidence="1">
        <location>
            <begin position="26"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="336" mass="37167" checksum="DDC93142FF2B93F2" modified="2024-05-29" version="1">MTYRFTLVVLFVLLATLSANNVVNGFRVGSDGNQDLMKKAVEDALLNTAKQPPIAKDDAPPLRNQLLNTEIPCLYEYWSRPDIHTFGNMGLGGSIHAAMAPFATKMIDMKAYGGQDVRKLISEELRIKLDVDGARVCDLCCGVGISTRALGKAFHDAELIVGVDTSPEMISMAKAISSHEQGVRSALARHNQGLKNLLGQKHKAITEAMTVIDTDPYPDRRHFDATYELANAENTELPNDTFNLVTIMYAFHEVPKEARSRIIQEAKRLLKVGGTLAVVDISPTYTPSKYMLAGEPFVIEYQQNIDKQLGSVPGFMFSKRKEIVPGHVNMWLLTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YM72</accession>
    <name>A0AAD8YM72_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2OG-Fe(II) oxygenase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001123</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YM72"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA alkylation repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.590:FF:000052">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.30">
        <property type="entry name" value="Impact, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032854">
        <property type="entry name" value="ALKBH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036956">
        <property type="entry name" value="Impact_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31212">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31212:SF4">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="1">
        <location>
            <begin position="360"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1749184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="601" mass="66084" checksum="30DC3D928E7BD4CF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YNE1</accession>
    <name>A0AAD8YNE1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000414</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YNE1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="331"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="395"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="493" mass="54601" checksum="33EA6F6A53A1AE87" modified="2024-05-29" version="1">MPESETVRRRKIFPHLSSDEAAAKESDEKKQGENDEAYDNAKSNKPTAAAAANNNNVVRNTESSVHHLLPLPLVIITLLCSGLFWVMSFRDAFATGQPLLLNLSSAPSLAQAELSLLDHTKSQKWYHDDDSSKAYWKSARGGLGSIRPYTSDDNDMGGLFVRKVTGVAAMGYHSTKLWSIVFQSAPVPSLLDGQIKMKGASWSIGHYDPILTLGMLGNCCIAAFYMMRIEELRNAGAEPLVAMLVMASLIEALVFGAYLMSRRMSMKKTKKVIVGNKQQQPQKQPKRPAQKKKGSKDKDASSPSSSLPATQEYNPQEDPNSIPSRIALRTVLIVSSIISLISVRDLFFPGTIISFIPRDDIYLEWTGAFFHSPPPDTVESDEYGLESPLYAGDKFMGQLLGLYLVLGCVWKFASVCAWSKGNKAMEFKSPENVDRHGVVSSKMIWKAQAFGDMLLLFMLRMFAPAAKSASLDLRWHLMTVAYEMIILGLYGFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3X3</accession>
    <name>A0AAD9D3X3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Photosystem I P700 chlorophyll a apoprotein A2</fullName>
            <ecNumber evidence="20">1.97.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="20">PSI-B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="20">PsaB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="primary">psaB</name>
        <name evidence="22" type="ORF">QTG54_017252</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="22"/>
    <reference evidence="22" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="20">PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19 20">
            <text>reduced [plastocyanin] + hnu + oxidized [2Fe-2S]-[ferredoxin] = oxidized [plastocyanin] + reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:30407"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10039"/>
            <dbReference type="Rhea" id="RHEA-COMP:10040"/>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
            <dbReference type="ChEBI" id="CHEBI:30212"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:49552"/>
            <dbReference type="EC" id="1.97.1.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="18 20">The PsaA/B heterodimer binds the P700 chlorophyll special pair and subsequent electron acceptors. PSI consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The eukaryotic PSI reaction center is composed of at least 11 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 20">Plastid</location>
            <location evidence="1 20">Chloroplast thylakoid membrane</location>
            <topology evidence="1 20">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 20">Belongs to the PsaA/PsaB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.97.1.12" evidence="20"/>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3X3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1130.10:FF:000001">
        <property type="entry name" value="Photosystem I P700 chlorophyll a apoprotein A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1130.10">
        <property type="entry name" value="Photosystem I PsaA/PsaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00482">
        <property type="entry name" value="PSI_PsaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001280">
        <property type="entry name" value="PSI_PsaA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020586">
        <property type="entry name" value="PSI_PsaA/B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036408">
        <property type="entry name" value="PSI_PsaA/B_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006244">
        <property type="entry name" value="PSI_PsaB"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01336">
        <property type="entry name" value="psaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30128">
        <property type="entry name" value="OUTER MEMBRANE PROTEIN, OMPA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30128:SF19">
        <property type="entry name" value="PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00223">
        <property type="entry name" value="PsaA_PsaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002905">
        <property type="entry name" value="PSI_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00257">
        <property type="entry name" value="PHOTSYSPSAAB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81558">
        <property type="entry name" value="Photosystem I subunits PsaA/PsaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00419">
        <property type="entry name" value="PHOTOSYSTEM_I_PSAAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 20" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5 20" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="22" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="13 20" id="KW-0157">Chromophore</keyword>
    <keyword evidence="11 20" id="KW-0249">Electron transport</keyword>
    <keyword evidence="15 20" id="KW-0408">Iron</keyword>
    <keyword evidence="16 20" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10 20" id="KW-0460">Magnesium</keyword>
    <keyword evidence="17 20 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 20" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14 20" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 20" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="9 20" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="22" id="KW-0934">Plastid</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="20" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="7 20 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 20 21" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 20" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="272"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="374"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="416"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="517"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="574"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="644"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="706"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="558"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="567"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="20">
        <location>
            <position position="653"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>B1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="20">
        <location>
            <position position="661"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>B3</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="669"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>B3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="670"/>
        </location>
        <ligand>
            <name>phylloquinone</name>
            <dbReference type="ChEBI" id="CHEBI:18067"/>
            <label>B</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00026002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00048912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAK1732209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="733" mass="81992" checksum="58646AE6A7F39EE4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D460</accession>
    <name>A0AAD9D460_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000070">
        <property type="protein sequence ID" value="KAK1732359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D460"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="200" mass="23182" checksum="D66621FBEF3F07A8" modified="2024-05-29" version="1">MAVPPEDDLNVVLIRHHIHWMKEEWLLWRFKSKKEIIVGVIGEMIRLIFIVGWFLSLIKDEGCSFNHGCDYYSADNDASAGLNWRRLMRKCFVCFSDFKLRLVPILLFHLLLTAIVRRRRVDCVRILWVVLSMYIERIPGLQWKVDLFFSRSLVSFWGAIIMNLFRSFYYGVEGSNGAEGINGEEGTSSQQYIGAPSIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4H7</accession>
    <name>A0AAD9D4H7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_015966</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000050">
        <property type="protein sequence ID" value="KAK1733407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4H7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16454">
        <property type="entry name" value="RING-H2_PA-TM-RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051826">
        <property type="entry name" value="E3_ubiquitin-ligase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765:SF411">
        <property type="entry name" value="OS02G0248440 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765">
        <property type="entry name" value="RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042196458" description="RING-type domain-containing protein" evidence="3">
        <location>
            <begin position="20"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="425"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="81"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="285"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="477"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="285"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="329"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="550"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1733407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="582" mass="63948" checksum="D40004AA10EA8353" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D593</accession>
    <name>A0AAD9D593_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sodium/calcium exchanger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_015089</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000040">
        <property type="protein sequence ID" value="KAK1734322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D593"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051359">
        <property type="entry name" value="CaCA_antiporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12266:SF0">
        <property type="entry name" value="MITOCHONDRIAL SODIUM_CALCIUM EXCHANGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12266">
        <property type="entry name" value="NA+/CA2+ K+ INDEPENDENT EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="308"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="379"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="476"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="827"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="860"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="889"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="919"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="960"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1005"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1030"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="8">
        <location>
            <begin position="316"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="8">
        <location>
            <begin position="897"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="106"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="174"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="278"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="565"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="645"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="121"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="174"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="185"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="647"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="672"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="713"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1734322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1049" mass="114201" checksum="885AFB13532A8C6A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5G3</accession>
    <name>A0AAD9D5G3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NAD-dependent protein lipoamidase sirtuin-4</fullName>
            <ecNumber evidence="6">2.3.1.286</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_015676</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.286" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000046">
        <property type="protein sequence ID" value="KAK1733633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5G3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017136">
        <property type="term" value="F:histone deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF10">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="5">
        <location>
            <begin position="64"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="270"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="322"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="282"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="327"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="339"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1733633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="455" mass="50263" checksum="E681619C70905605" modified="2024-05-29" version="1">MLAITTTRPALSFAWQVNAITRRQMISSSSSSSQRTRSLQMIYSSQRILPLHRPPDPSSFTNNTTDNESNYIQSQSTRLQNWLHTKKSILVITGAGMSTESGIPDYRGSNGSYFKGHKPIIHHDFMSNESSRKRYWARSLVGYSPFSTAQPNGGHEALARMEELGLIGVDLEGVVGEEVLECLGESCYGSMSINDNDDGDNTQQQQLLPRRLAIITQNVDILHSKGGSKHVLHLHGRGDIVRCMNCGVTRDRKEYHDHLSESNREWMEAAAATTATKSGMESGKKVRDNDGKKKKAASLRPDGDADWYQESYDGMSLPPCPHCGTVHDNNNINHQNGEQQQQQQQQQQQQQSFYKTDVVFFGDSVPRHRFDIAYAAVDAADGILCIGTSLAVHSAYRLAKRALDKGTEVAILNVGETRIESEGLDSSTGLVTKIESPIGDTLAEVVKSYTAAAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5V8</accession>
    <name>A0AAD9D5V8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_015313</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1734055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5V8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0085020">
        <property type="term" value="P:protein K6-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF8">
        <property type="entry name" value="BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="43"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="76"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="165"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="165"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="184"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="212"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="237"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1734055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="285" mass="31223" checksum="0A7AF853D6B3225C" modified="2024-05-29" version="1">MATAGDRYEERTGNIWSYSHRGDMSGLRAALSRGVCPNMSNTVGWTPSHAAAAGGHTKALRLLAKSGADFTIADRGGNLPAHQAAKNGHVHALRVLSEHGADITKVRLSQAKGKAARDFVIDAYKKAGVDADDEDEEEDAPVGYSRKQVISTAFWGPRRTPISTKIKKKIIKEKRLKKKEKAQNNDNNKNNDTSSDTDCNNEEPSYVETVRQMKRNKKQRQKQKQGRKETAHQTVFEDQDSNTIDDDQASATFSSDDSTEDSMGVNGFAALLLGDDSDSEKEAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5Z9</accession>
    <name>A0AAD9D5Z9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_015016</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000040">
        <property type="protein sequence ID" value="KAK1734249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5Z9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="225"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1734249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="274" mass="31183" checksum="7C2E783866C94096" modified="2024-05-29" version="1">MGRKRNQGKARKAAKAKAEDAEGVKKLQQLGLSHAKMLQDGTVFICLHGAGPLCFEGICHEFVTAFREEFYAEAFRKEFFYAANHIGDSLSSCLIAADDATVDEFAEMWNDSAKMEIAKSCFLSEGAQHILEGEYNHARENAVFARYLEQTIAIDLLKTQATMNWPKINELSRFVLDPTIRGDVHTLVKFFRKRIPCSCLDKKYEEVKSITKMGMCYNPDCPIPCAYVERSKTMYCSRCRSVTYCSRECQKAHWKLHKLHCEKCAALIAKFEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6B9</accession>
    <name>A0AAD9D6B9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_014783</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000038">
        <property type="protein sequence ID" value="KAK1734535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6B9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052420">
        <property type="entry name" value="Espin/Espin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153">
        <property type="entry name" value="ESPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153:SF8">
        <property type="entry name" value="FORKED, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="85"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1734535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="516" mass="57990" checksum="A7256C7C72B0A629" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6I3</accession>
    <name>A0AAD9D6I3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Formamidopyrimidine-DNA glycosylase H2TH DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014556</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6I3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003906">
        <property type="term" value="F:DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016799">
        <property type="term" value="F:hydrolase activity, hydrolyzing N-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015886">
        <property type="entry name" value="H2TH_FPG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_uS13-like_H2TH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06831">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="S13-like H2TH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Formamidopyrimidine-DNA glycosylase H2TH DNA-binding" evidence="1">
        <location>
            <begin position="50"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="127" mass="13988" checksum="090316DAE36032E4" modified="2024-05-29" version="1">MLCVVLEKKSKSTAAEEDVISVITEEADITGKEATILISLHMGMTDSNSGIVNKIANQKKVIKAILLDQRQVISGVGNWVADEVLYLECLNDGEEQLPEQWLFHRRWRGGGSKGTNSKDFNGKQSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6J8</accession>
    <name>A0AAD9D6J8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013468</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6J8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052420">
        <property type="entry name" value="Espin/Espin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153">
        <property type="entry name" value="ESPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153:SF8">
        <property type="entry name" value="FORKED, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="182" mass="19324" checksum="4F16A6591F9B60E2" modified="2024-05-29" version="1">MIEICPDLLSARDCLGRTPLHVAAGSAADPRLIKILAHVCLAACDVQDQDVDGKTPLHFACDSSSVLFEDVHNNESATPRPPCHDAICALLSESLAAATIEDADEMNPLKHTIMSNASLKSVKLLQSAAAKHLQGASMSTSLGPTTISLRRVSIHGRRGVMLSVCVCVLVKMLAGCIRRALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7X3</accession>
    <name>A0AAD9D7X3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Translation elongation factor 1-alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_013230</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat SWD2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7X3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016070">
        <property type="term" value="P:RNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037867">
        <property type="entry name" value="Swd2/WDR82"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19861:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 82"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19861">
        <property type="entry name" value="WD40 REPEAT PROTEIN SWD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Tr-type G" evidence="8">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="341"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="546"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1736094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="577" mass="62568" checksum="9768C97F3DA5B9A6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8H4</accession>
    <name>A0AAD9D8H4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012746</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8H4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1736724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="246" mass="26201" checksum="9F21970B0FA09608" modified="2024-05-29" version="1">MEHTVSDDSLPSFLAAKCSSKLVIEWRLFPTFIPSIKRCSAATMCSASCKQAEKVSTLPHNTPSLSPKIISPGFTVTPAHCTELTSTPSPTCCTVPAYGVILVEYAKHSNSATSRMGPSTTIPLTPLLVASVVNRLPATALVDPPVLTTRTSPAESSVNAERTARKSFGRGNCTVLATPIMTPPDCFGACRNFITSVSIKFSPLYFFKSGSSLVDEVSLWPLSASQSGPVPNFCSRLMMSLTSPFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D976</accession>
    <name>A0AAD9D976_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_010227</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D976"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1738911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="223" mass="26155" checksum="D234DEE43C678EFF" modified="2024-05-29" version="1">MQCQQMQMAASTSKNTKNNLECKSTSYIDVHDGREDKSIIQHASQQRQPLKVHDNNDDMPEILMGYDILTNLLNGHSNLWIVPTLRKLTFGNKLHEETQRYINIIQLAASERKRELRHLRQLEPRMTDHYQDEKPNQMADEIVKNVAWKVASNLSNRSDQFDVDFAFVQITSCTLVSSTALAVLKFETNRERIKWLKEVSVQYKLIRDEMRDTMLDYIRRGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9J1</accession>
    <name>A0AAD9D9J1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_011607</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9J1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008494">
        <property type="term" value="F:translation activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070935">
        <property type="term" value="P:3'-UTR-mediated mRNA stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045948">
        <property type="term" value="P:positive regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11176">
        <property type="entry name" value="BOULE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11176:SF57">
        <property type="entry name" value="PROTEIN BOULE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="40"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="102"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="133"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1737835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="569" mass="63124" checksum="42D1E2B36E65785D" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9K8</accession>
    <name>A0AAD9D9K8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_011500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9K8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007498">
        <property type="entry name" value="PqiA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34730:SF1">
        <property type="entry name" value="PARAQUAT-INDUCIBLE PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34730">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04403">
        <property type="entry name" value="PqiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042168492" evidence="3">
        <location>
            <begin position="18"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="373"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="419"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="511"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="576"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="616"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="664"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1737728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="705" mass="77153" checksum="4735308F333E9B53" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DA96</accession>
    <name>A0AAD9DA96_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Prolyl endopeptidase</fullName>
            <ecNumber evidence="6">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_010689</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Serine peptidase whose precise substrate specificity remains unclear. Does not cleave peptides after a arginine or lysine residue. Regulates trans-Golgi network morphology and sorting by regulating the membrane binding of the AP-1 complex. May play a role in the regulation of synaptic vesicle exocytosis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S9A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DA96"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.120">
        <property type="entry name" value="Prolyl oligopeptidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023302">
        <property type="entry name" value="Pept_S9A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002470">
        <property type="entry name" value="Peptidase_S9A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051543">
        <property type="entry name" value="Serine_Peptidase_S9A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11757:SF19">
        <property type="entry name" value="PROLYL ENDOPEPTIDASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11757">
        <property type="entry name" value="PROTEASE FAMILY S9A OLIGOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02897">
        <property type="entry name" value="Peptidase_S9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00862">
        <property type="entry name" value="PROLIGOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50993">
        <property type="entry name" value="Peptidase/esterase 'gauge' domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S9A N-terminal" evidence="8">
        <location>
            <begin position="87"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="7">
        <location>
            <begin position="572"/>
            <end position="790"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00045448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1738659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="793" mass="89876" checksum="6072BD87DEE5B10C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DA99</accession>
    <name>A0AAD9DA99_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">NADH dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_011104</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="9">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 24 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DA99"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902494">
        <property type="term" value="C:catalytic complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098796">
        <property type="term" value="C:membrane protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03064">
        <property type="entry name" value="TRX_Fd_NuoE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000022">
        <property type="entry name" value="NADH dehydrogenase flavoprotein 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1590:FF:000001">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1590">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002023">
        <property type="entry name" value="NuoE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042128">
        <property type="entry name" value="NuoE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041921">
        <property type="entry name" value="NuoE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01958">
        <property type="entry name" value="nuoE_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005725">
        <property type="entry name" value="PRK07539.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10371:SF3">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10371">
        <property type="entry name" value="NADH DEHYDROGENASE UBIQUINONE FLAVOPROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01257">
        <property type="entry name" value="2Fe-2S_thioredx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000216">
        <property type="entry name" value="NADH_DH_24kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01099">
        <property type="entry name" value="COMPLEX1_24K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="5 9" id="KW-0408">Iron</keyword>
    <keyword evidence="6 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000216-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1738435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="264" mass="29112" checksum="A484DB3B317A619F" modified="2024-05-29" version="1">MMSAARLLARRLPSAANRANAAGQLRSMGHAQSFHINTPDNTPETYFDFTEENYQYVNKVLSKYPANYKQSAIIPLLDLAQRQHGGWLPVAAMDKVASIVEAAPSRVYEVASFYTMFNRTKVGKYFIQLCGTTPCMICGSEDIKKTIEKHLGIKNGETTKDGMFTLLEVECLGACANAPMVQLNDDYYECLTPKTMVELLEACKEGKPPAMGKWGSLPMNGQVSCEGPLGKTSLWEVPEPPKVNVERFKDGAVDPASVKAHMSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DB21</accession>
    <name>A0AAD9DB21_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009833</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="647"/>
            <end position="679"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1287" mass="145222" checksum="B4F1DDA929CEBA91" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBF4</accession>
    <name>A0AAD9DBF4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Zn-dependent oligopeptidase (Family M3)</fullName>
            <ecNumber evidence="9">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_008414</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase M3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBF4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006518">
        <property type="term" value="P:peptide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06455">
        <property type="entry name" value="M3A_TOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.40">
        <property type="entry name" value="Endopeptidase. Chain P, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.10">
        <property type="entry name" value="Neurolysin, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024077">
        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024080">
        <property type="entry name" value="Neurolysin/TOP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804:SF84">
        <property type="entry name" value="SACCHAROLYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M3A/M3B catalytic" evidence="8">
        <location>
            <begin position="286"/>
            <end position="733"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1741162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="736" mass="82166" checksum="E4949F11E9B321DC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBI8</accession>
    <name>A0AAD9DBI8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009499</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBI8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="151" mass="17194" checksum="17DFE19AC81D2E41" modified="2024-05-29" version="1">MMTSHARAVTPLIEDKQGQGALRAQNQNSRKNVNNDSSDSDDKPNKRRKTNNKQAVLLNEFNQEFGDVESFFRSGGAQATRGQQEPISKVRSGLDSLFLPYHEARRLRIPEVLWIYSNPGFNDCPLDIPDHEDDEIELLPTRPSGRRFLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCB3</accession>
    <name>A0AAD9DCB3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008628</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCB3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="69"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="205"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="562"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="683"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="259"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="804"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="910"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1068"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="81"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="220"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="569"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1189" mass="136377" checksum="6DBE3F58B9BCBF0A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCV2</accession>
    <name>A0AAD9DCV2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_008312</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCV2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="43"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1741060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="171" mass="19274" checksum="936DA7E9D9914595" modified="2024-05-29" version="1">MSRQCPSFIQRDWSSNGQSDIMNTVMFSVFHKVKEVASQSGMDNRSASLCSGLVSGFATACVSTPFDWFKIQAQLSLTQNQESSSGSLHTKTNARRTDVLSICRHLWHDTNQQMTKVIQTIYRGHIPNLAREGVFTMVYLGTYDLISSAVKEKQYQRQISSSSIFLCRMLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DD46</accession>
    <name>A0AAD9DD46_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine aminopeptidase (Family S33)</fullName>
            <ecNumber evidence="3">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007851</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DD46"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051044">
        <property type="entry name" value="MAG_DAG_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11614">
        <property type="entry name" value="PHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="2">
        <location>
            <begin position="52"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="317" mass="33895" checksum="7265A05A44721C4A" modified="2024-05-29" version="1">MTSAEEPPRRASLSDDHPVLAAKSQTLTTRGIECALYKWTPPQNNNANGKNNIRGVAVVYHGFGAHSLYPTVRYASCLLAENGFIVYGLDFPGHGASPGKKGLLSGAEDLIQDGIAVAKVAQKEASSGEHGVNLPLYFVGSSMGGAIALAVADSLTEGSVNGVIMLAPMLSLKVGGTARSALGTLSSLPFLSTLPLIPHSATDSSKQYRDPERRAECDRNTMTNKSGLRPISAFTCVEITETIQKKFSQIKVPFLCMVAEEDVVVDNSKTEELMKLSPSKDKTLKSYPALHGLLCEPAPLLGIIEDDLIQWLVKRCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDJ1</accession>
    <name>A0AAD9DDJ1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-hydroxyacyl-[acyl-carrier-protein] dehydratase</fullName>
            <ecNumber evidence="2">4.2.1.59</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_007398</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.59" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDJ1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019171">
        <property type="term" value="F:(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01288">
        <property type="entry name" value="FabZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.129.10:FF:000001">
        <property type="entry name" value="3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00406">
        <property type="entry name" value="FabZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013114">
        <property type="entry name" value="FabA_FabZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010084">
        <property type="entry name" value="FabZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01750">
        <property type="entry name" value="fabZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000582">
        <property type="entry name" value="PRK00006.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30272">
        <property type="entry name" value="3-HYDROXYACYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30272:SF1">
        <property type="entry name" value="3-HYDROXYACYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07977">
        <property type="entry name" value="FabA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1741825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="222" mass="24081" checksum="49B6F267B43F78D4" modified="2024-05-29" version="1">MKQSQTQIQRNQSNKMKLALLATLATAATAFVAPSAPLTTRSPTQIFAEDEAEAAEVEEPAPRSAAEISALTSSVKTIFSLEDINGILPHRYPFLLVDKVVEYEQGKRAVGIKSVTLNEPHFTGHFPNRPIMPGVLQVEALAQLAGIICLQMEGAEPGAVFFFAGVDGVKWKKPVVPGDTLVMEVEIKKWNKRFGIASATGRAYVDGELAVELDEMKFALAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DE96</accession>
    <name>A0AAD9DE96_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lysine methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005594</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DE96"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF109">
        <property type="entry name" value="RIBOSOMAL LYSINE N-METHYLTRANSFERASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="451" mass="50247" checksum="11E48C0266B9F2CB" modified="2024-05-29" version="1" fragment="single">MLATTITDPLLSSPTQVQRHDDDMAVTFPPSLLDHDSQLLDSLTYSSTSCSSEQNDHHHHHHDEEEVIIEQAPTDDIEELEQEDDDEEEDETPFEQLMNRGNYLRQLRALALQDEMERRASTLFEEEKKEEDNLDSGSDIRNCNDEFGPHHGRFVVSPNVSCVVVSVSSDYLMSCLNDDEEEEELCDHVYTISPTSAVNNGEKVKVLEYNSYLAHQRYYDDLKHVDITYMDYGVIPHRPSTNNTNEQSALEGEGGSNESDGGRVVIEQRKRLGKGGFCWDAAFVLGEHVIANEADWNVDTGRKGGASVLELGAGTGLCGIMVGKATKSQVTITDLPELEELMGDNVRRNFGPSEDNDAAADNLSKEERSLITHLDGGKAKGTVTSRVLRWGVEEDYFLNNEDKQEEQTYDVIIGADIVASLYDPVALAQTLHALCGPTTKIYISSKSRLDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFV9</accession>
    <name>A0AAD9DFV9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002808</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFV9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="293" mass="33695" checksum="D02277B50710E192" modified="2024-05-29" version="1">MDKCIDSDDIVYALAAFLSPKDLVYLALTCKSFGAASGKTPWSRMEELARRQVSAAKDDVSFKWRHSDLLTIDGQESWINVYNRLHLLRTSIIFHTLINNDISYVDRNITHIRAKKSRSRGAVVSSDYSYAICQQSMDFQKNSGRHFVQYRVTGQSSTIKLGIMRPIHSRRKRKMKIPEYCEFCNSQEDPAFTGLKHHCLFGDLISNGDDVYGLLIDLGSSHICVYQNYKLVNINYMRFANLEGQFCWAVGMKKDQHRVSVRIENNWQDTCGASGPTPKENWELWHNLYNSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG89</accession>
    <name>A0AAD9DG89_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004041</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DG89"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050994">
        <property type="entry name" value="At_inactive_RLKs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48010:SF55">
        <property type="entry name" value="OS01G0607900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48010">
        <property type="entry name" value="OS05G0588300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="374" mass="41745" checksum="E5544A546CC7E722" modified="2024-05-29" version="1">MQSLNIEPERPKNPYGPGGRHSQDTSFISAKMYFVICLALFTMMGIIKMAMPVDDINDEWAKKGGASGGWGAEHNHPVIDNGSGGSVNPPKQNSPPAQTYYPLKSQSSNIDQGLNDKEFRSDDLMNALAPIVALPAQPRSEYKMYQEAANFVPEDLLYDTNTPHGKAFDFILNRDKRKLSGDDKHLFQRFVLTLIFYAWGELMRMIQKNITLLRMPEVGGRLHECHWVKKSLEDHFWGILSIESESDQRVGVTKCNNDMEVIELRLADLNLVGPVPSALGDLDELRYLSLDGNNFSGSIPDVFTGLTNLERVYLNFNEFNGVMPSSLCFLREEGVLEDLWSDCGGYPITCTCCTVCCDMVAECDEMASQQGGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGB5</accession>
    <name>A0AAD9DGB5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3082 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004116</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGB5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021434">
        <property type="entry name" value="DUF3082"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11282">
        <property type="entry name" value="DUF3082"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="166" mass="18488" checksum="EDF75D6ADC978FEC" modified="2024-05-29" version="1">MTEIQASVDKEKYGSGKTREYFKEFRSQKSEEERQRSIEEARDLNGVNPLVCIGGAAFAWACAGALWFFTTYLGALFVSHPLETDVYFIQRLTQVFRNMVMGLSSLASGFFGVVGIGIFLLGVRVGYGVMTGELDPTPIKKSKSDEIVLPDVWALMTGQTNRRGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGF3</accession>
    <name>A0AAD9DGF3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zinc-dependent peptidase, M16 (Insulinase) family</fullName>
            <ecNumber evidence="4">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_002869</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGF3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050626">
        <property type="entry name" value="Peptidase_M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032632">
        <property type="entry name" value="Peptidase_M16_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054734">
        <property type="entry name" value="PqqF-like_C_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43690:SF18">
        <property type="entry name" value="INSULIN-DEGRADING ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43690">
        <property type="entry name" value="NARDILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16187">
        <property type="entry name" value="Peptidase_M16_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22456">
        <property type="entry name" value="PqqF-like_C_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M16 middle/third" evidence="2">
        <location>
            <begin position="8"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Coenzyme PQQ synthesis protein F-like C-terminal lobe" evidence="3">
        <location>
            <begin position="257"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1746262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="401" mass="45464" checksum="FAAAA072627C2E3A" modified="2024-05-29" version="1">MKVINLDTIPNSLQSEFLKSIFADALAIETYDAYLAGLGWSLSKSSAGFTLTCHGYSDRLPDLALKLLKELTSPSFLEERHFETAKDKTIRGLSSFFESRRADSLAIYYRNLLLNYKGNGVEENLEIARAITLRDIEKHHAMIWADNDLSLEVLYTGNVSEKQARSFFSDATDVIDSTRALVTQKEAVEDNIADSWASGPLERRLPAGEDIELHFESKNPKEENGAVVVTYQSQHEGFKGKSLSSKETLERSACVRLISKIIREPCFNELRTKQQLGYIVSSFYDMSYSTNETPLTTSIDSLTVYVLSRKVEPKDVAARIDDFLLNFRSKLEDMPSKEIQDYAESLAKELTKPIRKLGTEASNQFGKIRRYAPETLYADNDSSLEDILLIMLRWWLQHCTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGY8</accession>
    <name>A0AAD9DGY8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Selenocysteine insertion sequence-binding protein 2-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_002161</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGY8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035368">
        <property type="term" value="F:selenocysteine insertion sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040051">
        <property type="entry name" value="SECISBP2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13284:SF4">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13284">
        <property type="entry name" value="GH01354P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="153"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="324"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="120"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="508"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="85"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="508"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1746817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="697" mass="75838" checksum="57A424908F24D081" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHB8</accession>
    <name>A0AAD9DHB8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cadmium-specific carbonic anhydrase</fullName>
            <ecNumber evidence="1">4.2.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_003799</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHB8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040931">
        <property type="entry name" value="CDCA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18484">
        <property type="entry name" value="CDCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159779">
        <property type="entry name" value="CdCA1 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1745875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="210" mass="22610" checksum="3CF6C18CFBEEB874" modified="2024-05-29" version="1">MPLTPEDIVGVLEGRGWEAEIVKAADMEGMIDICPKGILKCVDGRGSDNEAMAGPKMAGGIYAIAHNRHTTSIEGLKAITKEVAAKGHVPSVHGDHSKDMMGCGFFKLWLTGRFDDMGYPRPEFDADQGAQAVKEAGGFIEMHHGSHEEKVVLINLVENKTLEPQEDDQRFIVDGWAAGKFDLDVPNFLVAAAATVEMLGGPKKAKIIVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DI16</accession>
    <name>A0AAD9DI16_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DI16"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="313" mass="35867" checksum="7EB32C2ACCE975B0" modified="2024-05-29" version="1">MMLGAMASTGSKQLLLQLGRNISYFGGRSSALYRCPMQPSQHTPIKNTFFSSTAAAIDVEVEVEVEEPVKNTTYSDLIRNRNKPSEEPDKKSVEKEKKPPFTYGHIRGINREKGYAIIRDEVSNEQIHLKFTNIDISESAQHNAKFVNPVFSSGARVRFQVMPNPINSGAMSAYDVQRWNGNKIPLLHYKDALKIALRSRAWLGHRCYEILDEEQDAAAMSEQIRQAYEDSNKSTEWARSQLTDSNKIIRECKAELGNEVFDILENIYQIDDVQRKVEEAFLRCERTLKELELLGIREEEEEPRQKRNPVVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJ84</accession>
    <name>A0AAD9DJ84_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Origin recognition complex, subunit 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001698</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJ84"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020796">
        <property type="entry name" value="ORC5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047088">
        <property type="entry name" value="ORC5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12705">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12705:SF0">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14630">
        <property type="entry name" value="ORC5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="266"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="955" mass="106388" checksum="3CDC35DE1D6769F4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DK49</accession>
    <name>A0AAD9DK49_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001098</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DK49"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="8"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1749159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="74" mass="8349" checksum="51A7161577CD9409" modified="2024-05-29" version="1">MVKLRKYLSRTMRWSSKQSSHSNENRRDSVKTQLHLNLPDVHVCNSLSCNACSSAHSINFIRVATTNTSESSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DK52</accession>
    <name>A0AAD9DK52_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_000287</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DK52"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1748348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="324" mass="36705" checksum="8606E40725EBC28B" modified="2024-05-29" version="1">MIDPISTMRHNGNMNHSQLPAVGSSRRIPSYYCPTTWQILLLLALYSALSSVFLMERTVGGEETNKNHGNDGQAPTQGAFESALNEVTQLITDERTKSNINAEITRRDFNLTMWDKKTTGGLKDLDRIKLAAIYRNATSVFEWGLGESSFIAAEVGVPRYTGIDSDPTWIKAARDSSPDHFRFHLGDIGPTGHWGRPDRSRLKKSYLNYQFEPLVSEKAFDVYYVDGRMRPACALVAFLHASTRGDTEEEKSPIVIIHDYYHDKMSQNCSECRKFRWQYPYHRIEEVADLVDHSGAMLAVFKRKKGVTDGEIKALWQEMGLGDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-12-02" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6T7K2R8</accession>
    <name>A0A6T7K2R8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Aspartate-ammonia ligase</fullName>
            <ecNumber evidence="9">6.3.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_015271</name>
        <name evidence="8" type="ORF">SMAR0320_LOCUS14919</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.3.1.1" evidence="9"/>
    <dbReference type="EMBL" id="HBGZ01020754">
        <property type="protein sequence ID" value="CAD9614259.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1734013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6T7K2R8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004071">
        <property type="term" value="F:aspartate-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004618">
        <property type="entry name" value="AsnA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00669">
        <property type="entry name" value="asnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30073">
        <property type="entry name" value="ASPARTATE--AMMONIA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30073:SF5">
        <property type="entry name" value="ASPARTATE--AMMONIA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03590">
        <property type="entry name" value="AsnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001555">
        <property type="entry name" value="Asp_ammon_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="7">
        <location>
            <begin position="49"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CAD9614259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1734013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="374" mass="42139" checksum="245125A85F9DB11A" modified="2020-12-02" version="1">MACTLNRDDPLGGLPPKHCLNGGYKPVFTNRLQLEEALSFCKTTLENNLKENVNLVRVSAPLFVTRASGFNDNLNGVERPATFEPRDFPGTHLEVPFSLAKWKRWALHYYGVEAGKGIVTDFRGLRCDDDVDFTHSLYVDQFDWEKHIAAEDRNIDYLKATVKAIYKALYDTEQAVCKKYGIDAYLPEELTFATSDDMIKEHPTATPKERENILCEKHKAVFFIGIGGMKPDGQLRHDGRAPDYDDWITERPDGGHGLNGDLLLWNPVLKQSFEISSMGIRVNPEVLLKQLDLCGVNERKEFVWHKMLLDGTLPQTIGGGIGQSRTCQYLLRACHIGEVQHGWYNPKEVEILKKDGIQLLGLGEFDADPSAKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-12-02" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6U3X2W6</accession>
    <name>A0A6U3X2W6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Farnesyl pyrophosphate synthase</fullName>
            <ecNumber evidence="9">2.5.1.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_016247</name>
        <name evidence="7" type="ORF">SMAR0320_LOCUS15004</name>
        <name evidence="8" type="ORF">SMAR0320_LOCUS15006</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Pheromone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.10" evidence="9"/>
    <dbReference type="EMBL" id="HBGZ01020868">
        <property type="protein sequence ID" value="CAD9614497.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="HBGZ01020870">
        <property type="protein sequence ID" value="CAD9614504.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000054">
        <property type="protein sequence ID" value="KAK1733109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6U3X2W6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004337">
        <property type="term" value="F:(2E,6E)-farnesyl diphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004161">
        <property type="term" value="F:dimethylallyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045337">
        <property type="term" value="P:farnesyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042811">
        <property type="term" value="P:pheromone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.600.10:FF:000021">
        <property type="entry name" value="Farnesyl pyrophosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039702">
        <property type="entry name" value="FPS1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11525:SF0">
        <property type="entry name" value="FARNESYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11525">
        <property type="entry name" value="FARNESYL-PYROPHOSPHATE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01017">
        <property type="entry name" value="Polyprenyl_Transferase_Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 9" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00033740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CAD9614497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CAD9614504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1733109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="360" mass="41480" checksum="7025E4399D87C246" modified="2020-12-02" version="1">MTSTDKDAFLAIYKEIETDLIADIQNLPALSDSVKQQLIDYYSVCIPYTVPGGKMTRGLTVIKGVEVLKQRKLTDKEYKDAAILGWQVEWLQAFFLVADDIMDASITRRGSPCWYKKPNVTQDNAINDALILENMIYQTLRRHFKKHPSYVQILELFIDTTFQTEVGQHIDTNGTPYADGKRAPLDLSRFTLDRYQGCVRYKTCYYSFYLSCALALAYCGYDPDTTEGKALYQNAEDICMILGEYFQIQDDVLDAFAPPEVLGKIGTDIEDAKCSWLVCKALELVSEEQKEILMANYGKHDAEGVKKVKELYRELKLEELFQTYEEEQKKMCDDLIAKIEPQNFQDLFKFLLAKIYKRQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2LD81</accession>
    <name>A0A7S2LD81_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009018</name>
        <name evidence="1" type="ORF">SMAR0320_LOCUS10473</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="HBGZ01014636">
        <property type="protein sequence ID" value="CAD9601422.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S2LD81"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CAD9601422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="109" mass="12394" checksum="047A778F65B93803" modified="2021-06-02" version="1">MVSQAEVAEINTYFQNRMAESKKIWATRGKDARIAAAAAKANQPPTWRQLKGVPLMLHEIKHVGNRPFMVGFGLVSLGALYLQTKFTDEMKKDSLYWSTYHLKENKSAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSQ4</accession>
    <name>A0AAD8XSQ4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016476</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSQ4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="636" mass="72644" checksum="D0822A32C91EFF9E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XU20</accession>
    <name>A0AAD8XU20_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Bestrophin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_015858</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000049">
        <property type="protein sequence ID" value="KAK1733443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XU20"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044669">
        <property type="entry name" value="YneE/VCCN1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281">
        <property type="entry name" value="UPF0187 PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281:SF19">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION CHANNEL-FORMING PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25539">
        <property type="entry name" value="Bestrophin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042245620" evidence="8">
        <location>
            <begin position="36"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1733443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="422" mass="47427" checksum="C94DDB4622FB95AE" modified="2024-05-29" version="1">MIFCRSLHNFLNKTPKMKFLSALLLLALSPTQTTAFAPANNHAVVAAAPFATSLQMSPPAPESLLTETYGEGGRKYRRTVYTHNEWIKHRSSDRFIRNISSMINSGVYKSLGREVVATTAIATFLVVFNALTGGYTDFDGVQHEAIISSLPQLTLPLTPFTLLSPSLGLLLVFRTNSSYGRWDEARKFWGLNINHTRDLNRMATAWYGHDGIPVDPTLRAEHLRQVSLMTWAFVRSMKRHLSPPAEDEEAYVAELNARLSPEQAQAIIAAAHRPNRALYDLSVAIDRLPMHFMRKNEINKNLSIFEDTLGGSERLLSSPVPLFYSRHTARFLSTWLLLLPFAMYEPFKGSWNHVMEIPAIALASLFLFGIEELATQLEEPFTILPMQGFCDKIGANCDEIVGWRGQGLDEYVNEMYDGSPTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XU95</accession>
    <name>A0AAD8XU95_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015783</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000048">
        <property type="protein sequence ID" value="KAK1733495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XU95"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="91" mass="9400" checksum="968BFE69FA2D795D" modified="2024-05-29" version="1">MFTTTAQGAENAAAVMDSTTSGEASEGMNSTPMGDCLGRHQQEEICSGNELHPDGGLFGTTPTGGNLFGEGGFNQANLNTTPGTREILPFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUA3</accession>
    <name>A0AAD8XUA3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015798</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000048">
        <property type="protein sequence ID" value="KAK1733510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUA3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="250" mass="27804" checksum="D1B258F9A8CD1AE6" modified="2024-05-29" version="1">MAKGVKRKKSNTAGAAPAADARAIETEKDQTTADGINDVNAKNKKVVCIVYLMERNTCDDLDHAAQIILSEISSLKTKAKTKKLSTVYRRVEIKPCWTANLAHFRLLLHEVAYEEERNQEIYLIQPLQNASVKLTPNNIMDTITSFENSLYQGNLHFLVLHDAVESGSRPWKLTTFDDESLSLTISSLTEIACDGINNSDKIEEEDYQAAIEASLFTVNARQTQAAVEASLFTVNEADDDANEEKKPAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUJ6</accession>
    <name>A0AAD8XUJ6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_015391</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUJ6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052514">
        <property type="entry name" value="SAM-dependent_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34203">
        <property type="entry name" value="METHYLTRANSFERASE, FKBM FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34203:SF15">
        <property type="entry name" value="SLL1173 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase FkbM" evidence="4">
        <location>
            <begin position="434"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="62"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="167"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="77"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1733864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="603" mass="66978" checksum="613817F29BF80CF8" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVQ2</accession>
    <name>A0AAD8XVQ2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014806</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000038">
        <property type="protein sequence ID" value="KAK1734558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVQ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="123" mass="14841" checksum="CC4B8241E01EF586" modified="2024-05-29" version="1">MNAVYQCMRRNRDRKLFSGWCWYLSRESPDWYDGYHDLNCPDHPFTVDFVRARSRLGWRWRNEDGDSCEINWLDPEPDRICDADTSSTRSLQSIQEEIGFYKGHYHPPTAEEYNRLCDEYSED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW81</accession>
    <name>A0AAD8XW81_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tyrosine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Tyrosyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_014451</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>tRNA(Tyr) + L-tyrosine + ATP = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10220"/>
            <dbReference type="Rhea" id="RHEA-COMP:9706"/>
            <dbReference type="Rhea" id="RHEA-COMP:9707"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78536"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.1" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XW81"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004831">
        <property type="term" value="F:tyrosine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006437">
        <property type="term" value="P:tyrosyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000085">
        <property type="entry name" value="Tyrosine--tRNA ligase 1 cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.240.10">
        <property type="entry name" value="Tyrosyl-Transfer RNA Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050489">
        <property type="entry name" value="Tyr-tRNA_synthase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006330">
        <property type="entry name" value="PRK08560.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46264:SF4">
        <property type="entry name" value="TYROSINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46264">
        <property type="entry name" value="TYROSINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="276"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="710"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="285"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1734991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="798" mass="87244" checksum="D2D321690BB87C5B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW93</accession>
    <name>A0AAD8XW93_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XW93"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="84" mass="8774" checksum="A9622151B5C81D48" modified="2024-05-29" version="1">MLQAVLRHQPPAGRSFTCWLSTSTTMQALCLIILATIGVAKGGYAPKESPKLPDGFCPKETGTATATTGVAKTASALRSHNMRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWE8</accession>
    <name>A0AAD8XWE8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TMEM222 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWE8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008496">
        <property type="entry name" value="TMEM222/RTE1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20921">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 222"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20921:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 222"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05608">
        <property type="entry name" value="RTE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="181" mass="20230" checksum="FDFD6F6C766B5ADE" modified="2024-05-29" version="1">MASSNHDDTCIGINNHHHQQQQLHPLAFSILWSPLPPITWFLPFIGHMGITTSHGTACDFQGPYSVGDRGKMAFGTATRALQIDITSLPAGGAEQWDKAIAEANAEYRTRMHNICCDNCHSHVAWALNDMEITAFGIRQWDMVKLCFLVFFKGRFLSLGGFVTQFLPFGPFLLIVILVRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXQ4</accession>
    <name>A0AAD8XXQ4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_013522</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXQ4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1735816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="35" mass="4239" checksum="F2CF74E54AC9F891" modified="2024-05-29" version="1">MMIWELYCYALMRRIIWNGCILPTVSMLLAMDSYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXS2</accession>
    <name>A0AAD8XXS2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013552</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXS2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="72" mass="7413" checksum="8B6C1F703DCFBA25" modified="2024-05-29" version="1">MGGCGSKATHLDHVDDSVHVMLKHDRKKRKDIGASSGGYKPRTANPALDKLKAAEGAKPEGGDGATGITATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXX5</accession>
    <name>A0AAD8XXX5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_013434</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXX5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
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        <source>
            <dbReference type="EMBL" id="KAK1735728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="63" mass="6942" checksum="823C8A34CFEF1309" modified="2024-05-29" version="1">MDYHSFMNDGVKATTNCGCIAGKDCMVDKYAQRVIWKGEEINCSYAVTIAIVMRAGKSLVCCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXY8</accession>
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        <submittedName>
            <fullName evidence="6">Glutaredoxin family protein</fullName>
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        <name evidence="6" type="ORF">QTG54_013960</name>
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        <name type="scientific">Skeletonema marinoi</name>
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            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
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        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
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                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="GRX_PICOT_like"/>
        <property type="match status" value="1"/>
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    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033658">
        <property type="entry name" value="GRX_PICOT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="GLUTAREDOXIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293:SF73">
        <property type="entry name" value="GLUTAREDOXIN-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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            <begin position="165"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
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            <begin position="121"/>
            <end position="150"/>
        </location>
    </feature>
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        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="141"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1735346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="234" mass="25531" checksum="566FD582F3B7A38A" modified="2024-05-29" version="1">MSSSIVDIKNDTEAKAASLLDASALSGQKNVLFFYAEWHVPSAAGGPFDMVVKALAGQSGTDGVNIYRVLAEEAPTLSQKYNVTTVPTFIFLNSDGAAIERIDGGEDVARVTQCYSRLASSASTTTSSSSTQPSPTQQPEEQSEEKEEEQTLNNRLQSLITSSPIMLFLKGTPNAPKCGFSRQAIEMLTESNLTFGYFNILEDDEVRQGLKSYSDWPTFPQFYVKGELVGDWIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XY30</accession>
    <name>A0AAD8XY30_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013755</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1603"/>
            <end position="1678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="11"/>
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        </location>
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    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="1138"/>
            <end position="1187"/>
        </location>
    </feature>
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            <end position="1530"/>
        </location>
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            <begin position="1543"/>
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        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="91"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
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        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="166"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
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            <end position="348"/>
        </location>
    </feature>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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        </location>
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        </location>
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    </feature>
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        <location>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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        </location>
    </feature>
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        <location>
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        <location>
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    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
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    </feature>
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    </feature>
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    </feature>
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    </feature>
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        </location>
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    </feature>
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        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
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            <end position="1226"/>
        </location>
    </feature>
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        <location>
            <begin position="1240"/>
            <end position="1249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1964" mass="217506" checksum="9FE3F31E5417BB92" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYA4</accession>
    <name>A0AAD8XYA4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cryptochrome/deoxyribodipyrimidine photolyase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_013255</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="4">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA photolyase class-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYA4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003904">
        <property type="term" value="F:deoxyribodipyrimidine photo-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032922">
        <property type="term" value="P:circadian regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043153">
        <property type="term" value="P:entrainment of circadian clock by photoperiod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.579.10">
        <property type="entry name" value="DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="CRYPTOCHROME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455:SF18">
        <property type="entry name" value="SI:CH1073-390K14.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="Cryptochrome/photolyase FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="Cryptochrome/photolyase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0274">FAD</keyword>
    <keyword evidence="2 4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="6">
        <location>
            <begin position="12"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="545"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="545"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="597"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602081-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1736119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="703" mass="79377" checksum="A085D72A8ADB0622" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZF6</accession>
    <name>A0AAD8XZF6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_012786</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZF6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012094">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033">
        <property type="entry name" value="TRNA(ILE)-LYSIDINE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033:SF1">
        <property type="entry name" value="TRNA(ILE)-LYSIDINE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal" evidence="5">
        <location>
            <begin position="13"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1736764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="412" mass="48252" checksum="A614ED84DA6BDF0A" modified="2024-05-29" version="1">MFDLDNDGTDGSKEVKCELHVAHFNHEQRGDNSDGDEAFVQRLRRILFSKVERNDENAIRGNSFTQDIARKWRRRKLRDLLSDLVLQTNNNTMCDTNRWGAILTAHHGDDSDETILLKLLEEHICQIYGNGSKNNGFFLVFFHLCRILCKTYVTTSQKRHHKFLESNALEWREDESNATNKYKRNKVRNELIPLMRELAGGEQALQKRFNNIDQQSRAISKDLKERATSYLASMPSQSEFWLPGDEVDILCEEAFYIWASKVTDRKLQLSYDQINRIKFQVENYPGKLQWTIDVGDLWRVQRNGNVLTLVHETESISDSLPWYIVETNHVLFDVNDQLESDTELIIKLPPKMESSSLSMKRVKDVGNMRFLPQWRKGRSPIKIKELLRGQKIHCIFETKHRSYVSLMDLKTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZI5</accession>
    <name>A0AAD8XZI5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Importin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_012635</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZI5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057672">
        <property type="entry name" value="TPR_IPO4/5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25780">
        <property type="entry name" value="TPR_IPO5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="IPO4/5-like TPR repeats" evidence="9">
        <location>
            <begin position="76"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="8">
        <location>
            <begin position="388"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF25780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1736613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="972" mass="104077" checksum="9B69BDB447E7C6D7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZN5</accession>
    <name>A0AAD8XZN5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZN5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="817" mass="91721" checksum="79772257667D1CBD" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0I2</accession>
    <name>A0AAD8Y0I2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012216</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0I2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="100" mass="11424" checksum="2C6BE1A204D198BC" modified="2024-05-29" version="1">MIGNLVARSGLRAATQTVARTQRRKMGDGPFTDAMHVKKNKYVEEWNGRREITEKAFEVGPDNLPAIFLCVFVFPFTVYTFTRRELIIKGDPRYKKSGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y166</accession>
    <name>A0AAD8Y166_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1737026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y166"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041920541" evidence="1">
        <location>
            <begin position="21"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="277" mass="30833" checksum="423EC42F275EA8F0" modified="2024-05-29" version="1">MYYNANVFVTTLSLMIFVTAQQNINALMLLSDVPTPSFIIDMQALRRIAEPPLNDNGDIPSIRCPKNNLLLQPISNTKRNNRVMDCQFPTVEGQQAIGYLHTTVTRGRDDAIPDEDEPISTFLAEVDLDPTLCRNDAHLVLGLNNHHVGSYYWARSAGAGSSMEAPGVGYGSSKSNSKGVLRWLDEGGPTACNSNDGKRSEWVNFLRRHDTVQLLPNDGQDTLLEFYKRQSLSRIDEDRKGEENTSTRIFGISNEGRPMGSEPAVVCEWRCILEEGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1Y0</accession>
    <name>A0AAD8Y1Y0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UVR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011831</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1Y0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042167386" description="UVR domain-containing protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="182"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="309"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="377" mass="42662" checksum="434C9D58E6DE60B5" modified="2024-05-29" version="1">MKHIITISIIFLGTLCLRSSAFARMPKPFLCMRATFKLDDKVSSNAAGDDSLFDSEDAAAIDAHDLSDSGLEAAAMERAVMLAEEYKEQQLKKKEMDRRNEPCVGGAALINSLEEQHAEVRKTAFTDDDESLLEAEDAAAIDAHDLSDSGLEAAAMERAVMLAEEYKEEQIKKNNKERTDRIKSIEEHYKQINKDIEAIERLIKEADDADHASGHLLERTFSDNDAADLALMMMEKSVVAATDRLEMRLEKVKQTEQEVRTALEKKYTSKALAESIERERHAAEMRFLSNKYRNDDVSFSAVHDNDKVLHDAHRQEHDAELRLEKAIEEDIATKKDLEQMIENKAALKEVLHELQEIIHEHAALAMEKENARKSPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y238</accession>
    <name>A0AAD8Y238_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GDP-fucose protein O-fucosyltransferase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y238"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042004837" description="GDP-fucose protein O-fucosyltransferase 1" evidence="1">
        <location>
            <begin position="25"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="464" mass="53088" checksum="59B2CDBF11DC64FE" modified="2024-05-29" version="1">MTTLRTVIPFCLVIVLFNLRLDLSRFIPEGETAPQSAVSPKNHSALSNDEYLKWLQEARHRSLNLSSTEEPIRIMYRAMNGLGHQLTRLSAAYHFAMLYQIPRVWPTHNPYCRGNSTIFTIYDYLIGEGQLMVDIPFFGDNNLYRNPNLFPRPNITLDHQDQQRVIHFSNEVQGYGHARAGKLWSIEYLKKGNALGKEVTDYQLYHQLMLLFEHKHKARIQKVLEATRFNEHTVFGLHIRTGNGETGDFTFKGRGMNDLDGWVARVVLLLCDYEQKHSHYFTKKPLMVYVGTDTGSVMQKLRAASNKTCEIPFVSSDQTFVEEGKSVTWNLGYDDLDKCLTGWEDMFLDMYLFTRCNSVMAGTYSSFTQSAPLSFMMHKAKRQQLQQQGEGDEQHPHYFCDVGVDGNRMDCASTLIGWLNQTTSMTWGVLNATKQRMKHEIMFPVLEGGGAIAQAFGRAGIKMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2I3</accession>
    <name>A0AAD8Y2I3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Prolyl 4-hydroxylase alpha subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011007</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2I3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="302" mass="34238" checksum="F6A7C0DE97F7754A" modified="2024-05-29" version="1">MADTSKNNCSTIASQECIDKIRAKLNAKQAQHVIQTRSMTVKSRSTKKSSKQKVAPIAAHQAKSPPSIKGKVPTSTTDSTNVEVLTVLGKTVHMVDPDRKVFVIDLLSPETCDEIRMMADNHTLNAKKDAEVWRTLYTYTKMDLPVVEVKDMVSKYTDNILHDVKKIVGVIFGMRREAMRLRPRSWKEPHLLLYQALDGKTHHTGIEMHYDGCDVTWQAMLTRQDEYEGGGTYFRSLRKTIRLKQGQVLVHPGELYHKGIDITYGVRCLLICFTDGMNPKILDDSRQEDDDPKYETNVLVCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3D4</accession>
    <name>A0AAD8Y3D4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Heme-dependent peroxidase</fullName>
            <ecNumber evidence="10">1.11.1.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_010237</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the peroxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.7" evidence="10"/>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3D4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140825">
        <property type="term" value="F:lactoperoxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00314">
        <property type="entry name" value="plant_peroxidase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF36">
        <property type="entry name" value="L-ASCORBATE PEROXIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 10" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042217675" evidence="8">
        <location>
            <begin position="29"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="9">
        <location>
            <begin position="179"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="468"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="469"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="500"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="523"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1738921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="557" mass="62281" checksum="EFEA035C4B789C1D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3T2</accession>
    <name>A0AAD8Y3T2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nascent polypeptide-associated complex subunit alpha-like UBA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_010359</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3T2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1310.10">
        <property type="entry name" value="Nucleoid-associated protein YbaB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036894">
        <property type="entry name" value="YbaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004401">
        <property type="entry name" value="YbaB/EbfC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33449">
        <property type="entry name" value="NUCLEOID-ASSOCIATED PROTEIN YBAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33449:SF1">
        <property type="entry name" value="NUCLEOID-ASSOCIATED PROTEIN YBAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82607">
        <property type="entry name" value="YbaB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041932687" description="Nascent polypeptide-associated complex subunit alpha-like UBA domain-containing protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1739043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="175" mass="18505" checksum="1150A968F8CB2D2E" modified="2024-05-29" version="1">MKTATIATLLLTASSATAFSTTRISNVVATHQSSSTSLNLFGSKPKDPNAPEGAPGQPGMMDQLAMFKKAQEIASKKKRLDDELANETITGSAADGNIEITVKYIPPQLPTNPTPGYEAAEVTINEEYLEGVSSEDLSVALVEAIRDGEAKATARVGEKYKELEEDMKGIMGGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4M2</accession>
    <name>A0AAD8Y4M2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Gamma-glutamyltranspeptidase</fullName>
            <ecNumber evidence="3">3.4.19.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009343</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.13" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4M2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036374">
        <property type="term" value="F:glutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052896">
        <property type="entry name" value="GGT-like_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043138">
        <property type="entry name" value="GGT_lsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043137">
        <property type="entry name" value="GGT_ssub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43881">
        <property type="entry name" value="GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43881:SF1">
        <property type="entry name" value="GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01019">
        <property type="entry name" value="G_glu_transpept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01210">
        <property type="entry name" value="GGTRANSPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAP" evidence="2">
        <location>
            <begin position="1065"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1238" mass="135139" checksum="A69B54575A637E95" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4X9</accession>
    <name>A0AAD8Y4X9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF1279 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010511</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4X9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045866">
        <property type="entry name" value="FAM210A/B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009688">
        <property type="entry name" value="FAM210A/B-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21377:SF18">
        <property type="entry name" value="DUF1279 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21377">
        <property type="entry name" value="PROTEIN FAM210B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06916">
        <property type="entry name" value="FAM210A-B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1279" evidence="2">
        <location>
            <begin position="123"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="279" mass="30878" checksum="CA194F859E2D83E1" modified="2024-05-29" version="1">MSKMNSVVRLPSSNLFKQFISSGPLSSPISGAYRASNGTKNLLLCNYWRGIHLDFFACYNQQRPYHRQSNPNPCKTASVGVAPNFIESSWMRFNRRYSSTMPHNSSSSSNNEVGKEPKKGESKARILFNKYGYVFVGTYLSIYVLTLISFFFGLDSGLLDPGTLAQVFKVSKNLACETADVIGPTGTGASMNEAANAYADEVSAEVKEDGRTLVEIVKSHMRRFEWTSGYAQKLEENPHLANLGVAWFIVKLTEPIRLAAAVIVTPKVAKMLGRKVPKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y593</accession>
    <name>A0AAD8Y593_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009703</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y593"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1739944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="146" mass="15432" checksum="667BB795F5232E82" modified="2024-05-29" version="1">MSIVNVDGKEWTMSYNGHNKATERIFFLVLPPGSYTGVFYDENDEVVSPEWVNVAAHAKPKCLDYVSADDFTFTTTGVATDYCHKAVSSGDICCSSQCGGKCGGSNCCNHGSGGCGGCCAGAIGRSGRICEHFYDTSCVIPPEESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5W4</accession>
    <name>A0AAD8Y5W4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009547</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5W4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042120774" evidence="1">
        <location>
            <begin position="18"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="139" mass="15249" checksum="D4ECCDFC2E207170" modified="2024-05-29" version="1">MCKLMALLVLLITIILSLQDFEVEGFKCDATTNHVGVDISSLPRGGAAAAALNPFPSGYNPFGYGLTDLGKEYLSYDGSLDSDVGRFLSSLKSGKRKSAPVMKEQWLEVVRVSKQGQSMRIYRKLDEMISFCLKAGFID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y899</accession>
    <name>A0AAD8Y899_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Divalent cation transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_008270</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC41A transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y899"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.20">
        <property type="entry name" value="SLC41 divalent cation transporters, integral membrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006667">
        <property type="entry name" value="SLC41_membr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036739">
        <property type="entry name" value="SLC41_membr_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41394">
        <property type="entry name" value="MAGNESIUM TRANSPORTER MGTE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41394:SF5">
        <property type="entry name" value="SLC41A_MGTE INTEGRAL MEMBRANE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01769">
        <property type="entry name" value="MgtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161093">
        <property type="entry name" value="MgtE membrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042050317" evidence="10">
        <location>
            <begin position="30"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="254"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="283"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="401"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="SLC41A/MgtE integral membrane" evidence="11">
        <location>
            <begin position="289"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="28"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="75"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="87"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="192"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1741018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="432" mass="46716" checksum="764F7D6302454560" modified="2024-05-29" version="1">MVTTSSLATAASIASLVICCSHIAPSAEAFSSPSSTSNLFRPPPYSSSSRSSSVQPSKNNNKRISIFQSIIGTTNTQRRRQLHSSSEDASSSSDSTTTTATNGQDDLTKLKAENRLLQERLKLLQIQNDELLKQQQQGEKPIEQRLILEDFEGWPTDVARGSSTIVDGWNKREKRYTDELLTEGSAIDGSVGDSTTTTNDNGVEDDDELGLVSSGLDEDELCEYDDQSNKWTSGIGECPLEPNITFLDAMKSRAYWLVGLLALQSCSGFILSRNELLLQDHPVIIYFLTMLVGAGGNAGNQASVRVIRGLALGTLNPTTQSQFLSRELRMAFALSAILSIAGFTRAIIFQTPFPETMAVTIALSMIVFSSICLGAVLPLVLQKMGVDPAHSSTTIQVIMDILGVVLTVFVSTAVLDSVWGKTFVKTMGHMGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y979</accession>
    <name>A0AAD8Y979_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pentatricopeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_008021</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y979"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051222">
        <property type="entry name" value="PPR/CCM1_RNA-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47942:SF63">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47942">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT (TPR)-LIKE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042204939" evidence="3">
        <location>
            <begin position="30"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="410"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1741543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="591" mass="65240" checksum="A698A01A88C97A92" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9R1</accession>
    <name>A0AAD8Y9R1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Coatomer subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">QTG54_007198</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22948">
        <property type="entry name" value="Coatomer_WDAD_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.470:FF:000002">
        <property type="entry name" value="Coatomer subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000010">
        <property type="entry name" value="Coatomer subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006692">
        <property type="entry name" value="Beta-prop_COPA/B_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047312">
        <property type="entry name" value="Coatomer_alpha_WD-assoc_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016391">
        <property type="entry name" value="Coatomer_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010714">
        <property type="entry name" value="Coatomer_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050844">
        <property type="entry name" value="Coatomer_complex_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056176">
        <property type="entry name" value="TPR_COPA_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876">
        <property type="entry name" value="COATOMER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876:SF1">
        <property type="entry name" value="COATOMER SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04053">
        <property type="entry name" value="B-prop_COPA_B_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06957">
        <property type="entry name" value="COPI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23953">
        <property type="entry name" value="TPR_COPA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003354">
        <property type="entry name" value="Coatomer_alpha_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="12" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="5 11" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="65"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="107"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="152"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="241"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="285"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B second beta-propeller" evidence="14">
        <location>
            <begin position="419"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B TPR" evidence="16">
        <location>
            <begin position="689"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer alpha subunit C-terminal" evidence="15">
        <location>
            <begin position="917"/>
            <end position="1265"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="12">
        <location>
            <begin position="1094"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="905"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="915"/>
            <end position="926"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF06957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF23953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1741625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1285" mass="141270" checksum="BFC5A7FE638F8D87" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9Z0</accession>
    <name>A0AAD8Y9Z0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007342</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9Z0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="173" mass="19005" checksum="93FB52E7E6965BA0" modified="2024-05-29" version="1">MNTTHLFTEERPEIVVMHEIICASADPDVRGGAVGITSKESLQYKTPTIIHPRNVSSEESSSDTTCLSSSLIMQLAGINITEEKKSSTTPTTPSKRGSLPFTFSKPLQNRIKMAKRASAPPICLTSKKRVHSRRRNRVVILNNKIMTKTQGSRGSIDSSLNFASISLDFMVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YA98</accession>
    <name>A0AAD8YA98_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">AP-2 complex subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_007843</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Subunit of clathrin-associated adaptor protein complex that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Adaptor protein complexes are heterotetramers composed of two large adaptins (beta-type subunit and alpha-type or delta-type or epsilon-type or gamma-type subunit), a medium adaptin (mu-type subunit) and a small adaptin (sigma-type subunit).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Clathrin-coated vesicle membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
            <location evidence="2">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YA98"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030665">
        <property type="term" value="C:clathrin-coated vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000002">
        <property type="entry name" value="AP complex subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.10:FF:000012">
        <property type="entry name" value="Beta-adaptin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1150:FF:000002">
        <property type="entry name" value="Beta-adaptin-like protein C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026739">
        <property type="entry name" value="AP_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015151">
        <property type="entry name" value="B-adaptin_app_sub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013041">
        <property type="entry name" value="Clathrin_app_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013037">
        <property type="entry name" value="Clathrin_b-adaptin_app_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009028">
        <property type="entry name" value="Coatomer/calthrin_app_sub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11134">
        <property type="entry name" value="ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09066">
        <property type="entry name" value="B2-adapt-app_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01020">
        <property type="entry name" value="B2-adapt-app_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49348">
        <property type="entry name" value="Clathrin adaptor appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55711">
        <property type="entry name" value="Subdomain of clathrin and coatomer appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Beta-adaptin appendage C-terminal subdomain" evidence="12">
        <location>
            <begin position="799"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="600"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="605"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00056315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00065056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1741365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="917" mass="100587" checksum="EA765C29C6D030A6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAP2</accession>
    <name>A0AAD8YAP2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chlorophyllase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007702</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAP2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041957638" description="Chlorophyllase" evidence="1">
        <location>
            <begin position="21"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="233" mass="26389" checksum="3B562769DEDA7676" modified="2024-05-29" version="1">MMIDLIYYLLVLLFIPQKYTINALLCGQQEPRRLHIMSSSKNDDYYSVKQAGDLDKPVVDRRQIIIQSSTAVAAIFQQFTSPVISYADEESTQISRGTIFEIQDPNSYSAVVYIPKATDGKEQAKQTSLPLLVVLHGAGVNEHSALYEFTNPGGDHTNLPPYLLSTQQAPPSLSENFVVVAPYVGQGKRSLYDEPRSKMLSFIKWFNTYMSLRHSMMERTSQSTDRKCLYLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAV3</accession>
    <name>A0AAD8YAV3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007253</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAV3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="162" mass="18710" checksum="7425A7E1CE6F7F1B" modified="2024-05-29" version="1">MFSKQRWCICPPSRDSLEKEQQLKPKYVQETKTFGKVSGNQWHLRCARQEDSVDDDGDISISEASSSENEEEDGDDDDISITDQIPPPVLVQEDEERGGALSPWGNKCKAKQNVWRELDNKESSIHLMTVEQIHQRWAQKYPLTRFKNTFEAMKTQKRVLPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YC07</accession>
    <name>A0AAD8YC07_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF285 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_006371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YC07"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1742774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="258" mass="29395" checksum="61C2113C68B7FD8B" modified="2024-05-29" version="1">MPSCSPSSAPTEAPSKPTGVNLFYAIWVEGNEGCRNDGDEPDYMAVNPTEWLSSTMEACCKKYFVGYLYDACMGRYPPDHDDCNVMLFYPDWDGSNKNCLDDGKEPYYMLSNHQYFLSNTREECCEKFYYWDFYTCSGTTPELTHGEFYPDWSGGGSTCLADGNKIPDYMIGNQKWFLSTTLEKCCERHFYWDINDCLGTTAVGTDKWYASYEDQKCVQDCSGAPPCGGVAEPWDQKYTSKEQCCKGQLSWVAKCRFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YC73</accession>
    <name>A0AAD8YC73_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">BUD31 (G10) family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_005366</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BUD31 (G10) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YC73"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001748">
        <property type="entry name" value="BUD31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19411:SF0">
        <property type="entry name" value="PROTEIN BUD31 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19411">
        <property type="entry name" value="PROTEIN BUD31-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01125">
        <property type="entry name" value="BUD31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00322">
        <property type="entry name" value="G10"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="176"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="176"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="188"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="203"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="227"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1743769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="257" mass="28775" checksum="D63533000EA80771" modified="2024-05-29" version="1">MSANRWDPKAKKPPKGFNYLVPVLSALENELRDKVRESNAGKRNTESMWPVHQINWQRSRYVYDMYYTHGKITKKVYDYCIKNKLVDAALIAKWKKPGYERLCSTYVINPNNYKFGTTSICRVPLKDRSPEAKTAQDPTTGCRDVLGSGAASEYFWNKYGQNLAAVQVAREKRMEEMEQKRLREEEANSTAAAASAAAGGGDSETDDDSDDDDDYGPTPAAWASEGGKLEAESERLAEGGDDTDDYKQPAKKLKSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCC2</accession>
    <name>A0AAD8YCC2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCC2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="511"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="587"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="712"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="326"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="511"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="538"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="723"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="847" mass="92651" checksum="54EDB81CF05D05E1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCG5</accession>
    <name>A0AAD8YCG5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">WRKY19-like zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005209</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCG5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056866">
        <property type="entry name" value="Znf_WRKY19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24906">
        <property type="entry name" value="Zf_WRKY19"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="1">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="1">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="289" mass="30551" checksum="A6C9FE744D622002" modified="2024-05-29" version="1">MRLLSGKSLPKKQPRTRSCIVEGCTTQIVKGKACAAHQCNKEDCTNKATEEGGTCLKHGGKRKYKYKQCSSEGCTNQAKNGGVCVKHGAKQDRCCHEGCNNVIKEQGVCIKHGAQVKQCSKDGCTNQAQKGGVCMKHGAQVKQCSKEGCTNNAVKGGVCKKHGAQVKQCSKEGCTNQAKKGGVCMKHGAQVKRCSTDGCTKYAVKGGVCVKHGAQVKQCSKEGCTNDARNGGVCMKHGAQVKQCSKEGCTNQAKKGGVCMKHGAQVKRCSTDGCTKYAQKGGVCIKHGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDZ2</accession>
    <name>A0AAD8YDZ2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_005876</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDZ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:RNA nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24141">
        <property type="entry name" value="2-5A-DEPENDENT RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24141:SF1">
        <property type="entry name" value="2-5A-DEPENDENT RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="243"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="276"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1743255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="391" mass="42710" checksum="2BDDB0BC9DA8E3A5" modified="2024-05-29" version="1">MPPYPLVPINEEGSWTQLKDDKNSSCNNSVATSSSGILDDPDFNFDPEAVDFEPLLVSGTGKILSYHSEDHIKYYHSSGSYDDDDEDESTVCDASTVVTSASLETHVISNSGGRRRSSRSRRRENNATWNLPVIIRVTGTLALATFMSMRMLSRPQILPRNGSSYQVQTTVAKPEPTYASASVVVTDISTSEVAAGSSYAANQPLFDAVKTNNIELTRLLLDGVSKTAKETNNNYDINCEDPQGMTPLIEATLVGNVDLVKLLLSHGARAQPLPGFLHTPLRAACLTANLDLIRLLLDEGADPNARSDGGRTPLMGACYLRPQFDALPNREELSFAAVQLMLSDPRTSIEDRNSFGESALDLCRSRNYDKSSNLLRSVISQRRSESKQKVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YE85</accession>
    <name>A0AAD8YE85_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_006011</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YE85"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066">
        <property type="entry name" value="RHOMBOID-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066:SF21">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="227"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1743390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="277" mass="31354" checksum="643A30B339924B76" modified="2024-05-29" version="1">MSSSQLSNPKAVWFLGAPVSKAIVITAVVTYIGAEMNKLHQALIFDTTKIFEHAQFYRIFVCNLTFGSMGELIFGLLALCPLLRRFEREMGSRKFGAFIVYTSILSTVIELLFFNIFFDIERYSGPYPQLGAVLGLFHKFTPRMHPKFFGVLGYDFSEKSITYGLCAQVILSGGFSTITPTFFGFVSGLLAVKWSETELPDFVYTIAGLIGKVITDEAPAVMMSRSVQRGGANRTRRAPTGEQEQQHHHRHNLHDHLRRLQRKQLHNLLQWDLIESP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YED8</accession>
    <name>A0AAD8YED8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005517</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YED8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="192" mass="20739" checksum="AF648A86C00F510F" modified="2024-05-29" version="1">MVPFKKKSDSIAKSSNAKSPTSNATTNTTPTSNNNNCTTTSPPSDDFSARRSARVAVGEYAADNDTWVEALAVCELPRKAGGGGTNNSGNASTILYATAEARKMAQAQLEEMRNTYANAAVRRRLEREELSKVKEEKKLLQRQSNGGGKSGGGRLSRLFKKTGLVSEERKSSNTISENDDENDQHGDDDALY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YES3</accession>
    <name>A0AAD8YES3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Polyamine aminopropyltransferase</fullName>
            <ecNumber evidence="16">2.5.1.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">QTG54_005046</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.16" evidence="16"/>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004014">
        <property type="term" value="F:adenosylmethionine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004766">
        <property type="term" value="F:spermidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.90.10">
        <property type="entry name" value="S-adenosylmethionine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00198">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003826">
        <property type="entry name" value="AdoMetDC_fam_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030373">
        <property type="entry name" value="PABS_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016067">
        <property type="entry name" value="S-AdoMet_deCO2ase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001045">
        <property type="entry name" value="Spermi_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558:SF11">
        <property type="entry name" value="SPERMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558">
        <property type="entry name" value="SPERMIDINE/SPERMINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02675">
        <property type="entry name" value="AdoMet_dc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01564">
        <property type="entry name" value="Spermine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56276">
        <property type="entry name" value="S-adenosylmethionine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01330">
        <property type="entry name" value="PABS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="5" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0704">Schiff base</keyword>
    <keyword evidence="4 12 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0865">Zymogen</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="127"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="302"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="434"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="471"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="505"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="531"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1367"/>
            <end position="1384"/>
        </location>
    </feature>
    <feature type="domain" description="PABS" evidence="15">
        <location>
            <begin position="741"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="569"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="592"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="603"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="634"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="962"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1744513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1387" mass="153581" checksum="7D3943DD354D4D75" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YF60</accession>
    <name>A0AAD8YF60_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Lactoylglutathione lyase</fullName>
            <ecNumber evidence="3 9">4.4.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glyoxalase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_003298</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(R)-S-lactoylglutathione = methylglyoxal + glutathione</text>
            <dbReference type="Rhea" id="RHEA:19069"/>
            <dbReference type="ChEBI" id="CHEBI:17158"/>
            <dbReference type="ChEBI" id="CHEBI:57474"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="EC" id="4.4.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glyoxalase I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.5" evidence="3 9"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YF60"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004462">
        <property type="term" value="F:lactoylglutathione lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07233">
        <property type="entry name" value="GlxI_Zn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004361">
        <property type="entry name" value="Glyoxalase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018146">
        <property type="entry name" value="Glyoxalase_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00068">
        <property type="entry name" value="glyox_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10374:SF30">
        <property type="entry name" value="LACTOYLGLUTATHIONE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10374">
        <property type="entry name" value="LACTOYLGLUTATHIONE LYASE GLYOXALASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00934">
        <property type="entry name" value="GLYOXALASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00935">
        <property type="entry name" value="GLYOXALASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="5 8 9" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042176031" description="Lactoylglutathione lyase" evidence="10">
        <location>
            <begin position="21"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="11">
        <location>
            <begin position="106"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR604361-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR604361-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1745374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="290" mass="31854" checksum="D2925A0AD3855914" modified="2024-05-29" version="1">MRFASTLAAAVALTSSTVSAFVAPSTSISTTATTTDLKMSEVEQPDVSAYMTGARPPLETIREMPLLVAKIVYYVKCTFSSRKSSKLTHHLHSSKPLQQEGTENYIMQQTMVRVKDPKASLDFYCNVLGFKLLMYREFPQWEFNVYFVAPIADASTIPEDEDGRWAMCMNTPGCLELTWNYGSEKEDAKYVYNTGNGDSTGTSDGQKIKGGFGHIGITVPNVYRACERFKEMGCEFHKSPNGGGMKGLAFIKDPDGYLVEILPQGKMVPEAIDCMGVAADGGEGYKDNSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFU2</accession>
    <name>A0AAD8YFU2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heat shock factor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_004778</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFU2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000479">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF206">
        <property type="entry name" value="HSF-TYPE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="6">
        <location>
            <begin position="319"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="273"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="590"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="113"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1744245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="611" mass="65343" checksum="7FA3C401EA767603" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFX9</accession>
    <name>A0AAD8YFX9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Trehalose-6-phosphate synthase</fullName>
            <ecNumber evidence="2">2.4.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004018</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.15" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFX9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003825">
        <property type="term" value="F:alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004805">
        <property type="term" value="F:trehalose-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1020">
        <property type="entry name" value="Trehalose-6-phosphate phosphatase related protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003337">
        <property type="entry name" value="Trehalose_PPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00685">
        <property type="entry name" value="T6PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788:SF109">
        <property type="entry name" value="CBM20 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="TREHALOSE-6-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00982">
        <property type="entry name" value="Glyco_transf_20"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02358">
        <property type="entry name" value="Trehalose_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1268" mass="139915" checksum="CA4160FB3094D2F8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFY7</accession>
    <name>A0AAD8YFY7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transmembrane amino acid transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_004509</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFY7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF349">
        <property type="entry name" value="AMINO ACID TRANSPORTER TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="308"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="394"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="416"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="448"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="7">
        <location>
            <begin position="94"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1745218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="490" mass="53292" checksum="179BC48A825ECA48" modified="2024-05-29" version="1">MTDQDAEANGSPSRERANLLADGSGSGGGLVEMFVPTSPGRGLHHDDDLNEDKHMLSDHFELEDGDSFYSDDGSDLSLEIDGGGDPHGMAVGSATPTQVAINIFISFVGAGLLGLPYAFSRSGWLLGSLSLCAVSSTNVYAMLLLVKCRKRLERQGITGIKGYGDVGREVMGPWGEVLVNVCLVISQAGFATAYLIFIGANIQKVTNGMASRALIIYACVPLLSLLVQFRNMKTLSPFSLIADVANVLGFSCVLFQDFEYYTHDDNIEAVDFRGLIYVTSVCIYSLEGVGLILPLESSCADREGFPRLLKQTITGITILMAVFGTCGYVAFGNQTISPISLNLKGESAAFVQVALCLALYLTYPIMMFPVSDVLENLFLSDSSKPPRRYCPSRTVRVMIVLVTATIAYSLPNFGKFLELVGASICTLLGFILPCYFHLRVFGRKEMKMWELLFNIFIIVVAVFFAFVGTIDAIMKLLEDDDEVIEGNLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFZ6</accession>
    <name>A0AAD8YFZ6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">diphthine methyl ester synthase</fullName>
            <ecNumber evidence="4">2.1.1.314</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_004180</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 4 S-adenosyl-L-methionine = diphthine methyl ester-[translation elongation factor 2] + 4 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:42652"/>
            <dbReference type="Rhea" id="RHEA-COMP:9749"/>
            <dbReference type="Rhea" id="RHEA-COMP:10173"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73995"/>
            <dbReference type="ChEBI" id="CHEBI:79005"/>
            <dbReference type="EC" id="2.1.1.314"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the diphthine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.314" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFZ6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141133">
        <property type="term" value="F:diphthine methyl ester synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="entry name" value="Methyltransferase, Cobalt-precorrin-4 Transmethylase, Domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004551">
        <property type="entry name" value="Dphthn_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10882:SF0">
        <property type="entry name" value="DIPHTHINE METHYL ESTER SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10882">
        <property type="entry name" value="DIPHTHINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="Tetrapyrrole methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Tetrapyrrole methylase" evidence="6">
        <location>
            <begin position="88"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1744889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="257" mass="28989" checksum="C4B67E9A783883B0" modified="2024-05-29" version="1" fragment="single">TIHYRPGPIRRKRCHRPWPRTHQIIGQNLSRSLHISFKRGKERLEAFTVVMISLLPIATLWNATLKISMSQPKRECFISRSWRSSMRDTHSDIMLRAREEGVKVEVVHNASAMGAVGCCGLQLYNFGQTVSILTLTMKRGKIVYLPPRFMTVNEASDQLIESEEDLKKGAYLPDKTLCVGLARLGQVDQCIIAGTLEELKEADFGAPLHCLIICGEVHDLELESLRPFLVPNSAFQIDAEGTLFKREDAAEENDAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGE9</accession>
    <name>A0AAD8YGE9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004276</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGE9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="793"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="805"/>
            <end position="814"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="857" mass="96986" checksum="1EDF44AD984F947F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGP0</accession>
    <name>A0AAD8YGP0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004495</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGP0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050769">
        <property type="entry name" value="NAT_camello-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947">
        <property type="entry name" value="GNAT FAMILY N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947:SF37">
        <property type="entry name" value="LD18367P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="306"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="453" mass="51141" checksum="A06940FBF0CBE246" modified="2024-05-29" version="1">MASSKEKYVRRSISVHLIRHGESKNNQVYRDAQRLFKGGTPDFDLKSWTKYVAEHRVADPGLSDVGQEQASRLSHYLEPHLANQAGEVRFVISPMRRTIETMLPTLTAMNRNSNENPHVKTVINGFYFESEGCHTREKVEPGMNAEQIAECLSPAGVQDASYVGFQNGPENGWYAYGKVLKLVTSLSNVLHDFTCGDGFLDEQLMEAERSEVEDIFDAGVTLPGEENDKCHNRFEPRARGEELPSLWTRRFHVLGITELEYFGKGRFLLMSSNQRRMLHNWWSLKDGWSYLMPSDKILLDSEVAFAFSDDVQPHIAEQTEALRSLYLTKSGSSLSQDELDTTHHKSNALTVVVKRGLQVVGCASLDERTGRLSDVVVRPSARRSQVGRSLIDAVKNHAIQSQKFDKIIVEPYTSESKAFFEKMGFELTEDSTGESTPMRLFTWSASYNSIILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YH16</accession>
    <name>A0AAD8YH16_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Hook C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YH16"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="230" mass="26022" checksum="362A99AE8FD96433" modified="2024-05-29" version="1">MDGLENQTQNYADQIMKLERENASIPALEKTLEESQTLAKKLEARNNEAEDALRARNAEISNLKNDLVTSDKSKNMYEDELNELRATQEGAEAAALALSPQADNDKLKRLEVDNSNLKAKVEQLESGASEGGRAAELEKELADKNTEVSKLQNDKEKLEAYTKKTLQKFQEKYLVALQDCKAKLKEKHDKIEALEMRSANEKMAQKREERLLSSAIYELGLGIMQNRLKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHA6</accession>
    <name>A0AAD8YHA6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NFACT protein RNA binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003166</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHA6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990112">
        <property type="term" value="C:RQC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
        <property type="term" value="P:rescue of stalled ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059101">
        <property type="entry name" value="NFACT-R_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051608">
        <property type="entry name" value="RQC_Subunit_NEMF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15239">
        <property type="entry name" value="NUCLEAR EXPORT MEDIATOR FACTOR NEMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15239:SF6">
        <property type="entry name" value="RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18297">
        <property type="entry name" value="NFACT-R_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05833">
        <property type="entry name" value="NFACT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NFACT protein RNA binding" evidence="2">
        <location>
            <begin position="149"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="329" mass="37120" checksum="31A51A4980EF724A" modified="2024-05-29" version="1">MNRANLIVSNLYRLPPGTTELEVEDWENDGNIVKLVLNTKDYTNFQEESDALFAAARKMKRGSAVVEELLAKTLEGEEALNDAQMDLQSMESSVLDEGTMILIQERLERTAKKTGWKPPKIEQSEEQSKPRRNETKKSQGNKARKPNPRELTSPSGHKVLVGRNRRDNEAICFALSKPTDIWMHARGCPGAHVLLCSRRGSPKVTDDDLQFAADLAAFYSDARTERRAEITTAEPKHITKPRGAPPGAVTLRQEGKTLLGKPDDVAEELKEARELSGANWSELGYRKGGKRANNKKKTAAVEKETAKKRREEARENNKRRKRKEESDWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YI04</accession>
    <name>A0AAD8YI04_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002245</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YI04"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31469">
        <property type="entry name" value="OS07G0633600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31469:SF8">
        <property type="entry name" value="OS07G0641000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="184" mass="20377" checksum="4035D47B06A00045" modified="2024-05-29" version="1">MTMGQPKARRASPSTNASSQIIYVLFVGTCLFFTLTGIVLHHWLADPHNVHKHAMQQFEMNHLGGHAKVDEQKKKRSVKLQSAVLDSGEKPPPPVHHDLAGLSCTDHGGPSDEIAKEMIYWSDIPSDDKFVSPIGANSIKRKYLTFDPDGGGFNNIRMSIETMIVMVMAHAMSRTLVMPPSQQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YI28</accession>
    <name>A0AAD8YI28_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003611</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YI28"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042007366" description="Transmembrane protein" evidence="2">
        <location>
            <begin position="29"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="333" mass="34192" checksum="B67E00E55CD24073" modified="2024-05-29" version="1">MMKRSSPTRRTATISAALLLLYSSGVLCFTVPHSSSRRCDTQQLSIPRGCHNSCTKLFVGTNLDNNNNNEDDTPSLGEMQTMITDVGVKIVAVALFGFILINTLSFATSVTTTVFSALFDEIGREATQLFSILSSIFFSIMSGIFGFVQVAAPAIGKGAVAAGKAAAPVIGSTAKSFGEAAAPVLESTAKSIGEAAGPIVQDVTDQISQTAAPYVQPVMESVDSSVKGAVDSISNSVDANLMSPLRDAATSVTDSVNTAVDSSIREATRAVDDSIVAPINAAKESVTSAVDSTIKGATDSAIGAMDGAMKGAVDAVSNSFYSSGLSGTDTTLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIJ2</accession>
    <name>A0AAD8YIJ2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_002076</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIJ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000362">
        <property type="entry name" value="GBP2p Poly(A+) RNA-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF3">
        <property type="entry name" value="FI21236P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="101"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="175"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="201"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1746732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="244" mass="25976" checksum="C74FA1EF1B1D6D28" modified="2024-05-29" version="1">MRDAGEVQFAEVMMMNDGRSKGCGIVEFADEEGAQNAIDTLNDTELCGRQIFVREDREQKVSGGGHHGQHGHGGQHGGGLNRVGGGAGGGGGRYNNQLGNVNVYVGNLAYETTWQELKDHMRRVGNIDKADILQGNDGRSKGCGIVIYQSPKEAQRAIRELQNSELNGRPIFVREDRESSSGGGGGGGFGNNNRGGGSGGRNDNNNFGYRNNNNSRTSGNLMPGAPSEQGCNVCRQSLLGYRMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIK3</accession>
    <name>A0AAD8YIK3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIK3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="276"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="461" mass="51189" checksum="88F9991773FE5424" modified="2024-05-29" version="1">MYRCDNDLRRTALRSEELLTGANSAAQVRSPEPARADYTDSSFAVRKRKFLPFSLHTAVHKTTMMATSTFSNEDDGSRSSSDTSYDMNMTEDEAMAIWLQRNEEIGERVREREAAEAAQQRASSSSPHHSSREGSSSPGGSSDDCDESLHSHRSDSVESGDTNSGFQHAAAVTHSDAWNRAISHNVMGEYDPYNTDPAYQNAYHAYQRFVDMNQPGVADNFVASTPGLAALMEQRRHLMARQRHLDFQLQQMDHQMHTSPMISSCHDTNYDALLSSQSSAAPPSQDHQGGHHSRTNNTPLSPSRMHDEIVKSEEGLFSITRVAPHPTFRSSSSTAAVENNNPTHHVSAATSAQILEYKRLQQAHSSQLLKSGDNSSKGTTSTNTQPSYFYAFAYRTQYTSRAVTCSCCQSRMYTDPLAEYMFCQSCAQISKVEGGAVGEDTVESRWEGKMQEAEDMMDMGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIV9</accession>
    <name>A0AAD8YIV9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Calmodulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003935</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1746011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIV9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2130">
        <property type="entry name" value="F-spondin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009465">
        <property type="entry name" value="Spondin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038678">
        <property type="entry name" value="Spondin_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF038123">
        <property type="entry name" value="NF038123_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041901996" description="Calmodulin" evidence="2">
        <location>
            <begin position="21"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="523" mass="58963" checksum="D5FAEC7AB4BE9CA5" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKA5</accession>
    <name>A0AAD8YKA5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PSME3-interacting protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_002186</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKA5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039845">
        <property type="entry name" value="FAM192A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019331">
        <property type="entry name" value="FAM192A/Fyv6_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13495">
        <property type="entry name" value="NEFA-INTERACTING NUCLEAR PROTEIN NIP30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13495:SF0">
        <property type="entry name" value="PSME3-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10187">
        <property type="entry name" value="FAM192A_Fyv6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAM192A/Fyv6 N-terminal" evidence="4">
        <location>
            <begin position="5"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="111"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="122"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="175"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1746842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="233" mass="25410" checksum="5347B65D7E43AD75" modified="2024-05-29" version="1">MSLSFVKSAVLSSTDGISHNEETTINTSETASIRASSTNSASHKPLFEQLRANKEIQDAKDDEFQKSIRGMQALDDEDVAHLDAIEEQKREVEYKVKSGIEREVALFHAAREDRGLVQTVVEDQEGGDDGDGSNKNDDEDKKSPGGDDTAKISAVPAAKKQIVPKFTIKKKRKRVDPESKDDAAQKKISGSTELKKSNNNDGEKKQAEEEKPKNNNVAALLGLGCYGSDSDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKP3</accession>
    <name>A0AAD8YKP3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sirohydrochlorin ferrochelatase</fullName>
            <ecNumber evidence="2">4.99.1.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002459</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.99.1.4" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKP3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051266">
        <property type="term" value="F:sirohydrochlorin ferrochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1400">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050963">
        <property type="entry name" value="Sirohydro_Cobaltochel/CbiX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33542">
        <property type="entry name" value="SIROHYDROCHLORIN FERROCHELATASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33542:SF3">
        <property type="entry name" value="SIROHYDROCHLORIN FERROCHELATASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53800">
        <property type="entry name" value="Chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="374"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="560" mass="63923" checksum="17FE68091774049A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKR5</accession>
    <name>A0AAD8YKR5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Flavin-containing monooxygenase</fullName>
            <ecNumber evidence="6">1.14.13.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_002504</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FMO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKR5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="5">
        <location>
            <begin position="47"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1747160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="516" mass="57822" checksum="9E0D8E2A9165B37C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YL07</accession>
    <name>A0AAD8YL07_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Polyamine aminopropyltransferase</fullName>
            <ecNumber evidence="18">2.5.1.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">QTG54_000267</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.16" evidence="18"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004014">
        <property type="term" value="F:adenosylmethionine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004766">
        <property type="term" value="F:spermidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.90.10:FF:000025">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.90.10">
        <property type="entry name" value="S-adenosylmethionine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00198">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003826">
        <property type="entry name" value="AdoMetDC_fam_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030373">
        <property type="entry name" value="PABS_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016067">
        <property type="entry name" value="S-AdoMet_deCO2ase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001045">
        <property type="entry name" value="Spermi_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558:SF11">
        <property type="entry name" value="SPERMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558">
        <property type="entry name" value="SPERMIDINE/SPERMINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02675">
        <property type="entry name" value="AdoMet_dc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01564">
        <property type="entry name" value="Spermine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56276">
        <property type="entry name" value="S-adenosylmethionine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01330">
        <property type="entry name" value="PABS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="4" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 11" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0704">Schiff base</keyword>
    <keyword evidence="3 11 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0865">Zymogen</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="PABS" evidence="15">
        <location>
            <begin position="354"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="16">
        <location>
            <begin position="1954"/>
            <end position="2005"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="17">
        <location>
            <begin position="2155"/>
            <end position="2209"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="14">
        <location>
            <begin position="2155"/>
            <end position="2205"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="16">
        <location>
            <begin position="2158"/>
            <end position="2209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="136"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="837"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1077"/>
            <end position="1510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1569"/>
            <end position="1610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1859"/>
            <end position="1882"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="2113"/>
            <end position="2164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="2211"/>
            <end position="2289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="2444"/>
            <end position="2477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="197"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="838"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="891"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="907"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="929"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="1122"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1190"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="1239"/>
            <end position="1248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="1277"/>
            <end position="1292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1373"/>
            <end position="1385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1462"/>
            <end position="1476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1488"/>
            <end position="1506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1577"/>
            <end position="1610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="2136"/>
            <end position="2145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="2211"/>
            <end position="2226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="2227"/>
            <end position="2237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="2240"/>
            <end position="2251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="2263"/>
            <end position="2276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="2445"/>
            <end position="2477"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1748328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2477" mass="275104" checksum="1BB96DBF1E260BE1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YL11</accession>
    <name>A0AAD8YL11_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_002409</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YL11"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16574">
        <property type="entry name" value="RING-HC_Topors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058746">
        <property type="entry name" value="Znf_RING-type_Topors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46563">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46563:SF1">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="147"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="78"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="199"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="372"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="237"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="372"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="406"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="418"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1747065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="457" mass="47990" checksum="771E6F86C89F0E1F" modified="2024-05-29" version="1">MPRVTRNSAARLANANNNGSTTATTTELTAPSSVRTTRSQTTANNDNEEEEDAAPIVIRRSTRRAAIDAKARIAEETKARIERKRRSRRNVDNMEDGVAQQQHSPLANSLDLKPAALSSGAKKLAAQSFKSEENADDDLSQLEEFTCAICLDKPDTLVDLATISGCTHKFCFDCIDKWAETENKCPCCKQRFNRIDRVKKLPPATPPTTSRRGKRKRSDNTNNSGSNTRRRTGEATGGAASAASAAAAASAPRVNSRTVEDRNQQHMPAGLSFALLESIFNSAFMGPGGLGSMQAGGERGRTTFRFPVPPSMAGDGDLDDMAGMLRMILQDATIGGPSARFTVQVRRTTGPANAGGGGAGAAASAAAPPAAARASGGAASRASSSPRSSRGSSRASSNGESRASRQQRSTLFSYFGNSPSSRRSRSSASGAARSSSAARPASRRDSGVIDLAGSDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLM5</accession>
    <name>A0AAD8YLM5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001573</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLM5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="205" mass="22762" checksum="0D20F367893DB75D" modified="2024-05-29" version="1">MSVCDDGCFDFVDEEATLEEIEAAKGRWDSDIPFCGKYINSFPACVPSSSTLRIVPEWMSSDANEDLNAIREKDRRLQQETDAKIAERISLGRNTTDTFETRIAKMPTQRTHFQETLPLCQSACENMFRVCGFEQDVWICGKTSLMEMTNGPRGPFFLVSHFVFDCGGEPKAVCTPSIRGPASTFGVSLVINAGVASLVLLFLVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLU9</accession>
    <name>A0AAD8YLU9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Zeta toxin domain-containing protein</fullName>
            <ecNumber evidence="5">2.7.1.176</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_000306</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.176" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLU9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010488">
        <property type="entry name" value="Zeta_toxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06414">
        <property type="entry name" value="Zeta_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="Zeta toxin" evidence="4">
        <location>
            <begin position="208"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1748367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="418" mass="46804" checksum="CFF88B57D55D9625" modified="2024-05-29" version="1" fragment="single">RTNKLNLSSPSSPLCIALKNCLNRQQDDDDRTIMIHWLRQSTPLVGLIRIFASSAFAGICLFVLYNLTSSSSFQSVFPISPHHFNSRDILSFTSQYNSANDNNMGEAASPNSDEIDTVKMDGPVYKRASLLLNPTYPIPPSFSSDKSTEENYAADNMEFFGPFKSIRASLDYSYHGNYTQSRQLFQDRIVEKLLDGTIIEDSNGRGVCKTPNEPWIVFTAGVMGAGKSHTIKQLASRGLFPLQSYVVIDPDDIRQHFPEYVLYAMQSPEHAGELTHKEAGYVTEIVTAAALQRGHNVLVDGSLWDADWYKGYFEQLKKSYGNLRIAILHVTAPREAVFARAKHRAKVTGRVVPIETLELSLKHVPQSIKLLAPMVDYFCELDNSPDSEEIVLKTEGVTCDSFRDAWAQTCPFPQKGKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YN42</accession>
    <name>A0AAD8YN42_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Geranylgeranyl pyrophosphate synthase</fullName>
            <ecNumber evidence="9">2.5.1.29</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_000221</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.29" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YN42"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004311">
        <property type="term" value="F:geranylgeranyl diphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.600.10:FF:000001">
        <property type="entry name" value="Geranylgeranyl diphosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053378">
        <property type="entry name" value="Prenyl_diphosphate_synthase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF045485">
        <property type="entry name" value="FPPsyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43281">
        <property type="entry name" value="FARNESYL DIPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43281:SF1">
        <property type="entry name" value="FARNESYL DIPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01017">
        <property type="entry name" value="Polyprenyl_Transferase_Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7 9" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041948471" evidence="8">
        <location>
            <begin position="21"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1748282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="337" mass="35702" checksum="96E085C8D4378E94" modified="2024-05-29" version="1">MARFTYRAALLAVLLQSAAAFAPVKLPVSPPASTALNVASTAISLDEYLQSKIGPIEAALEASVKSRIPQTDKICESMAYSLMAGGKRIRPVLCIAACEMFGGSQETAMPTAVALEMIHTMSLIHDDLPSMDNDDMRRGKPTNHVIYGEDVAILAGDSLLSTSFEHVARHTKGVSADKIVDVIARLGASVGAEGLAGGQVMDLECEAKPGTTLDDLKWIHIHKTATLLQVAVASGAVLGGATPEEVEACEKFAMDIGLAFQVADDILDVTASTEDLGKTAGKDEATDKTTYVKLLGLEESKKYARELIDEAKECLAPFGDRAAPLLAIADFIVDRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPJ3</accession>
    <name>A0AAD8YPJ3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Prefoldin subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_001229</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPJ3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23163">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.370:FF:000002">
        <property type="entry name" value="Prefoldin subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027235">
        <property type="entry name" value="PFD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002777">
        <property type="entry name" value="PFD_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13303">
        <property type="entry name" value="PREFOLDIN SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01920">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="17"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1749290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="123" mass="14438" checksum="4F797F6E0D8B8CBA" modified="2024-05-29" version="1">MASTEPPISQQEIISTYRQMNSEMQSLIQQLTKAEMERNEHRLVEETLEPLDPDRRAFRLVGGVLVERTVKEVLPSVKENRVNLDTLTKHIEVKLEEKRKETFAWKAKYNIKTQEEMEAAQKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D497</accession>
    <name>A0AAD9D497_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015965</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000050">
        <property type="protein sequence ID" value="KAK1733406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D497"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="574" mass="63495" checksum="46AB79E0C39C1751" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5S6</accession>
    <name>A0AAD9D5S6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase</fullName>
            <ecNumber evidence="3">2.4.2.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">N(1)-alpha-phosphoribosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_015475</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>5,6-dimethylbenzimidazole + nicotinate beta-D-ribonucleotide = alpha-ribazole 5'-phosphate + nicotinate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11196"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15890"/>
            <dbReference type="ChEBI" id="CHEBI:32544"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:57918"/>
            <dbReference type="EC" id="2.4.2.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nucleoside biosynthesis; alpha-ribazole biosynthesis; alpha-ribazole from 5,6-dimethylbenzimidazole: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CobT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.21" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5S6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008939">
        <property type="term" value="F:nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02439">
        <property type="entry name" value="DMB-PRT_CobT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1610.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003200">
        <property type="entry name" value="Nict_dMeBzImd_PRibTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023195">
        <property type="entry name" value="Nict_dMeBzImd_PRibTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036087">
        <property type="entry name" value="Nict_dMeBzImd_PRibTrfase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43463">
        <property type="entry name" value="NICOTINATE-NUCLEOTIDE--DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43463:SF1">
        <property type="entry name" value="NICOTINATE-NUCLEOTIDE--DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02277">
        <property type="entry name" value="DBI_PRT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52733">
        <property type="entry name" value="Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="6 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="9"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1733948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="400" mass="41267" checksum="2363730386AE13CF" modified="2024-05-29" version="1">MSPNPSSPPEGAAAEPTPLATTLSDSKQSFTAKYEAARLYIDSLAKPVGSLGTLEDWGARMAALQQTTTPNADSAACLIFAADHGVAKDTSEGGRKCSAYPQIVSRKVLEALDHGIAGASVLSKCNNVELRVIDVGIADGPVSYEWSGNTVRLATSRIQGGTKNFCTGNALTEEQVKMCIDVGREETTKLMDEMGGANVIMFGEVGIGNTTTAAALIAALTGVDVATVCGSGASVTRDGINEAIVARKIDIVKEALDFHSNASSLNGNPMQALGAVGGAEICSMVGGMLEASKHDVAILVDGFIVTTAAMIACMIDPTVSRLLLFSTKSTEKGQVIAITTITEIATSNSIPVQTKPALDMGLRMGEASGCITSVPLLRSACATIASLATLNDVMCLEMGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D690</accession>
    <name>A0AAD9D690_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">26S proteasome AAA-ATPase subunit RPT1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_014001</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D690"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19502">
        <property type="entry name" value="RecA-like_PAN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000005">
        <property type="entry name" value="26S protease regulatory subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000440">
        <property type="entry name" value="26S protease regulatory subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000027">
        <property type="entry name" value="26S protease regulatory subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048723">
        <property type="entry name" value="OB_PRS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21236">
        <property type="entry name" value="OB_PRS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0647">Proteasome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="229"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1735387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="455" mass="49638" checksum="5A6ADF063DDAD612" modified="2024-05-29" version="1">MSSGECQTRNVAQDDDDQSAAPPPLDSEDIALLKSYGLGPYSVPIKEIEEEIKKHQQTVKDLIGIKESDTGLSQPSQWDLVGDKQMMQEEAPLQVARCTKIIAGEEEGAAANAGAAAAGGNDMSAQLAGNKYVINVKQIAKFVVGLGEKVAPTDIEEGMRVGVDRAKYSIQIPLPPKIDPTVSLMTVEDKPDVTYEDVGGAKDAMEKLREVLETPLLHPERFVALGIEPPKGVLLYGPPGTGKTLTARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFTMARSKRACIIFFDEIDAIGGARGGGEDNGSDNEVQRTMLQIVTELDGFDARGNIKVLMATNRPDTLDPALLRPGRLDRKVEFGLPDLEGRGHILKIHSKRMSCDRDIRFELIARLCPNTTGAELHSVCTEAGMFSIRARRKSVSEKDFLDSVNKVVKGYKKFSSTPKYMVYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6N6</accession>
    <name>A0AAD9D6N6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chloroplast stem-loop binding protein of 41 kDa a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_014676</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6N6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008743">
        <property type="term" value="F:L-threonine 3-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051225">
        <property type="entry name" value="NAD(P)_epim/dehydratase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42687">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42687:SF1">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042143137" evidence="2">
        <location>
            <begin position="21"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="36"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1734803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="349" mass="38190" checksum="E352AC67F1E98EDB" modified="2024-05-29" version="1">MVSFQKVIVVLPLIAGGASAFSLSMSSALIVQNKGGGHGELGFQLAKNLQSNPKITSITILQDSACNDAKEPFVSYASDIPNVNIIKADLADESMTAADMQSLLKQPFDYVWDNSSKGAVGAGKAVIDSAKEWNSKLLTYVSSAGIYQPNDVFPMPETTPIKESAGQVQYEKYAIESGLPFVSFRPQYIYGEKSNKWDYIDWYFDRLVRGETLPIPAPGTQKVSLTNSADVASLLASVLNDEAAAVEQTFFNCGTDELCDYDEVAKLCAEVAGTELNIQHYDVSLGKAKFPFRMTDFYVSPDLAKSKLGWEGAKNSLKDDLKWYFESYKARGGMTKDISFDQDKEVLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6R7</accession>
    <name>A0AAD9D6R7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo-keto reductase family protein</fullName>
            <ecNumber evidence="3">1.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013153</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6R7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041910102" evidence="2">
        <location>
            <begin position="25"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="257" mass="28552" checksum="967D3805402FD25A" modified="2024-05-29" version="1">MKIVATAMLGTILCTASLPKPSAAVSSRTIASFVASSIGRSTSSSPTTTSRNMMSTQTPEQKQSLIDCPTIPLRDGTSHPAIGFGTYKLWRQGTTDEPQRTAEDCVTDALNSGYRFLSAQSFMAMNKRSEKQSKQVVCLGRICSYAARFGLRQSRRVMMLFEHSWRRLSLILEQITLIFILSIGQCPGSMWMPTNGARSEEGGQGEKCWRIKYAVEDYKELLSAGITSEDKPVVNQIEINPFLYRKNTIDISKVKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7W8</accession>
    <name>A0AAD9D7W8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">subtilisin</fullName>
            <ecNumber evidence="7">3.4.21.62</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_012159</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides.</text>
            <dbReference type="EC" id="3.4.21.62"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.62" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7W8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07477">
        <property type="entry name" value="Peptidases_S8_Subtilisin_subset"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034202">
        <property type="entry name" value="Subtilisin_Carlsberg-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 8" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0720">Serine protease</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042118981" description="subtilisin" evidence="10">
        <location>
            <begin position="25"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="11">
        <location>
            <begin position="181"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="474"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="474"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="486"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="532"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="582"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="740"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="761"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1737292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="772" mass="80764" checksum="38DB33F63F2429AF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8C4</accession>
    <name>A0AAD9D8C4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sialate O-acetylesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011559</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8C4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005181">
        <property type="entry name" value="SASA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03629">
        <property type="entry name" value="SASA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sialate O-acetylesterase" evidence="2">
        <location>
            <begin position="101"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="308" mass="34417" checksum="86D1368FD402B780" modified="2024-05-29" version="1">MVGHTTSSESMTGSADYWNTIKSILDSYSAAASGGSGNLTSMEEQLYNAIYEANDNNGEANEYNDQVATTLTNGVMDLYKSGLLNDLDTPLQFGKDFELHKVARGGSGLYEHWYPNHGMHWNLLQSAIEERKGQQGEWKGFIWHQGSQAVWSAQQYGEDRSLTYYGNLTGLVSEVRELMFQNSITWRCKEEIPVVIVQVGFWPGYKDAANRTRDAQAKFCNQDPRAVLVKTDDLSRYYHYDAASFLISGNRIARAYQEALGGVVECPDDWVPSSSPSEKSMEPSMSLEPTVLRLETDLPSSINTTELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8H6</accession>
    <name>A0AAD9D8H6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Atlastin</fullName>
            <ecNumber evidence="8">3.6.5.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_012761</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8H6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.420">
        <property type="entry name" value="AHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030386">
        <property type="entry name" value="G_GB1_RHD3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036543">
        <property type="entry name" value="Guanylate-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015894">
        <property type="entry name" value="Guanylate-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10751">
        <property type="entry name" value="GUANYLATE BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02263">
        <property type="entry name" value="GBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48340">
        <property type="entry name" value="Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51715">
        <property type="entry name" value="G_GB1_RHD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="550"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="587"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="domain" description="GB1/RHD3-type G" evidence="7">
        <location>
            <begin position="109"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="15"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1736739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="633" mass="70521" checksum="96C7BE6B2349B6A3" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9K5</accession>
    <name>A0AAD9D9K5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Carbohydrate sulfotransferase</fullName>
            <ecNumber evidence="9">2.8.2.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_011621</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sulfotransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.2.-" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9K5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016051">
        <property type="term" value="P:carbohydrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018011">
        <property type="entry name" value="Carb_sulfotrans_8-10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005331">
        <property type="entry name" value="Sulfotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12137">
        <property type="entry name" value="CARBOHYDRATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12137:SF54">
        <property type="entry name" value="CARBOHYDRATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03567">
        <property type="entry name" value="Sulfotransfer_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1737849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="559" mass="63662" checksum="0AADD7F6BE9D4D76" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAJ0</accession>
    <name>A0AAD9DAJ0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">V-type proton ATPase subunit G</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_010688</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the V-ATPase G subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAJ0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.2950:FF:000001">
        <property type="entry name" value="V-type proton ATPase subunit G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005124">
        <property type="entry name" value="V-ATPase_G"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01147">
        <property type="entry name" value="V_ATP_synt_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12713:SF11">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12713">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03179">
        <property type="entry name" value="V-ATPase_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1738658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="123" mass="13300" checksum="9B3BAB6176ABEFE8" modified="2024-05-29" version="1">MNSGTGIQELMAAETRASQIVAEARIARGDRMKQAQVDADELIAAYRLEQQDAFDKKANADGGSGNNASAKLQAETNAEVQDMQGQFHQNAQKAVDVLLSKCCEVSLEVPSARIRSTQKIYGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBR7</accession>
    <name>A0AAD9DBR7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ubiquitin-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009737</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBR7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1739978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="228" mass="25390" checksum="12F2E36C107B78BA" modified="2024-05-29" version="1">MGGGGFSTFRYLESPDILHESQLQLLCEWIDFMWEKTALLTENADRVDMRLTLSEEQLHTIMSALDSSLEDKYKFSNVSEKFESLFHQVSHLPRSRGIGYKVALRATRGPTNSCIDFHCDGGYATSTSQIPLNSPAEYKGGQICFFVNDHLHFVPRPLGSLVQHPPNVLHGVTQVTEGTRKSLFIVDQYNGLGENGVVELTSDDVASYVAHRALVAGMKRTPVVDLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DC34</accession>
    <name>A0AAD9DC34_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DC34"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="26"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="188" mass="21490" checksum="AF223C3226196146" modified="2024-05-29" version="1">MVSNIALKPLRDMEMAEKLNAMNLDMEDAEAQREIDQRMRNLQEQQELEEMMRIKKEAEESCLVATKDHLLEFLRDHPDASYNEWIEDLHPENAHAGTLLEGLSKTIDHRFYVDESDHRRLWNDNLHTYSDPNSKGRAFVAARAKQMKDNGDYVDAEDLLSGGGDNFASGAAETNEGNTDGFDLINFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCB7</accession>
    <name>A0AAD9DCB7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Protein N-terminal glutamine amidohydrolase</fullName>
            <ecNumber evidence="3 8">3.5.1.122</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 8">Protein NH2-terminal glutamine deamidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_008824</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>N-terminal L-glutaminyl-[protein] + H2O = N-terminal L-glutamyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:50680"/>
            <dbReference type="Rhea" id="RHEA-COMP:12668"/>
            <dbReference type="Rhea" id="RHEA-COMP:12777"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:64721"/>
            <dbReference type="ChEBI" id="CHEBI:64722"/>
            <dbReference type="EC" id="3.5.1.122"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2 8">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the NTAQ1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.122" evidence="3 8"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCB7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008418">
        <property type="term" value="F:protein-N-terminal asparagine amidohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070773">
        <property type="term" value="F:protein-N-terminal glutamine amidohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.620.10">
        <property type="entry name" value="Protein N-terminal glutamine amidohydrolase, alpha beta roll"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037132">
        <property type="entry name" value="N_Gln_amidohydro_ab_roll_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039733">
        <property type="entry name" value="NTAQ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023128">
        <property type="entry name" value="Prot_N_Gln_amidohydro_ab_roll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13035">
        <property type="entry name" value="PROTEIN N-TERMINAL GLUTAMINE AMIDOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13035:SF0">
        <property type="entry name" value="PROTEIN N-TERMINAL GLUTAMINE AMIDOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09764">
        <property type="entry name" value="Nt_Gln_amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein N-terminal glutamine amidohydrolase alpha beta roll" evidence="9">
        <location>
            <begin position="29"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1740729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="246" mass="28339" checksum="FD4A25AD0DE9FB34" modified="2024-05-29" version="1">MNEQRPTGRASLSAESTALQSPSDHDLRVACYCEENAWRVAYRHLYTDASNSCSGNNKDWKYYIVFISNNHKACPMFMQRAIPKDDPREYVCWDYHVIVMRSAVQNNIGGTIVSEILDVDTWVTPYPTPLSKYLDESFPHATDPNLNKQYLPLFNVVRAEDFIRDFYSDRMHMFKSGKWNSPPPEYPPIMNGLKMDGNDSQERNELTGSNLDSYISMSGEGKCVFTLAEMYERSTDSNKKEWTECS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCM2</accession>
    <name>A0AAD9DCM2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCM2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="305" mass="34984" checksum="50560371986BD1D3" modified="2024-05-29" version="1">MELQEQLASKYATPPPTTWYESLDQLKSLSTTEDSCDQGKLWRLILDHPMTSYVPVQCQSCGHVVPDQYPTQQTDAEVGLREIAPTGDELELRAGWFRGPRQAVVFELTCKGCNAVSKWYRSGHPQILLNPNKWGRLCGDQEDLRLTLAKYLNIPVRLAVPLDWDHVWSEYSSGSSTWQVQDNSARNFCCRLDEGIGSWTRVWAIHSNPEWCKDVTRDYLTIQQNGGRADNNIDDKRMKRYEKITKDARMDKSGDLTQAKTVNGYVLLRANLSHGSITEELQRAVRDFGTKKWWELSYDDKSGIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCW7</accession>
    <name>A0AAD9DCW7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008372</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCW7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1741120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="77" mass="8970" checksum="B496A03C19B0D5DE" modified="2024-05-29" version="1">MTKYEDEDWKDLPEDVKAAAKKLGYTKKMWNGDKEPDCCDEYWDDLDEDQRQAATVLGYDKESWDKGGILDKCCVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DD69</accession>
    <name>A0AAD9DD69_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GPI inositol-deacylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005912</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DD69"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042171763" description="GPI inositol-deacylase" evidence="1">
        <location>
            <begin position="24"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="311" mass="34698" checksum="BA5A81D13EAAE7DE" modified="2024-05-29" version="1">MRALVRFYILVASALWTAHSCYGKLLPRRTKLTWVNGIAHMPEHMSDPTFVISTIFGGVKVDYCHNPSSMTSESDYLGFVKDGIQASTHVMMGRLTPEVDSLVEHLRDALKQVGRNGRVIHIAHSQGSVITWLAAQRLKPEECKRIEIISFGGAATICTSEFPFARCINYYSVNDPILNVVPSAVKALKSGFSFGDGMQQEIIFLASRTGDPATDHGLLNPTYLEALVWEGQRYQSLFLSPLGQMAGAAFVGPLSSTVTWFPNFAYEMTRRAFIAMARIFTLLWELVHVTITRLLGKGERYDPILLKIHDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDD3</accession>
    <name>A0AAD9DDD3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_007472</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDD3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041956780" description="SAP domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="domain" description="SAP" evidence="3">
        <location>
            <begin position="65"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1741899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="652" mass="73014" checksum="11CDA9434077FA82" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDG1</accession>
    <name>A0AAD9DDG1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">RUS1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_007562</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RUS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDG1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006968">
        <property type="entry name" value="RUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055412">
        <property type="entry name" value="UVB_sens_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054549">
        <property type="entry name" value="UVB_sens_RUS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12770:SF31">
        <property type="entry name" value="RUS FAMILY MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12770">
        <property type="entry name" value="RUS1 FAMILY PROTEIN C16ORF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24160">
        <property type="entry name" value="UVB_sens_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04884">
        <property type="entry name" value="UVB_sens_prot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="281"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="Protein root UVB sensitive/RUS" evidence="8">
        <location>
            <begin position="57"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Root UVB sensitive protein C-terminal" evidence="9">
        <location>
            <begin position="424"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1741989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="531" mass="59192" checksum="3ADBB5677726559E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DE15</accession>
    <name>A0AAD9DE15_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_006838</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DE15"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="81"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1742273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="310" mass="34589" checksum="F36139430A71F937" modified="2024-05-29" version="1">MSSDNDEIDDAKMMSCASCGIVECDEIKLKNCTDCDLVRYCGDECQENHAIQHEEAYKNRATELRDEFLFRQPESSYLGDCPICMLPMQLDLSKATVTACCSKLFCNGCAHAHANYLREGEGGFKYTCPFCREVSPTTKEESDKQRMKRIEANDPVAMRQEGIDQGKKGDYISAFEYCSKAAELGDAKAHYRVALMYWKGCGVEKDRGKEMYHTEEATIGGHPSARCYLGCVEWNNDNTERAVKHWIIAATQGHDDSIDLLMNAFKKGMVSKEDLAAALRAHQAAVDATKSPQREAAEEYCRSLASVVGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DE45</accession>
    <name>A0AAD9DE45_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004814</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DE45"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="233" mass="26819" checksum="DCF93FE828AC6E73" modified="2024-05-29" version="1">MKSESAYKHIDDDVIQKDIGFLHNFLIMVMTQSTSDSDVESVFRQITYNMSSIASYFEPLKGMHFSEMAEAFIEINRSHAGLQVQKALSLLNVLVVTHVLFEGKVPHSYAELRRFRQMQSKKTNITMNTDVRGEYVQIGKDRHVNSFLKACGLVTSMKEDDLLYITQTMDKDPGAFFNELCGEIKQAFNDRKNPNRKGAWCKWKRILEEVAADNKIHQKIINKWMGGISWKEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DER7</accession>
    <name>A0AAD9DER7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">YDG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_006605</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1743008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DER7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.280.10">
        <property type="entry name" value="SRA-YDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008676">
        <property type="entry name" value="MRG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053820">
        <property type="entry name" value="MSL3_chromo-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036987">
        <property type="entry name" value="SRA-YDG_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003105">
        <property type="entry name" value="SRA_YDG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10880:SF48">
        <property type="entry name" value="MORTALITY FACTOR 4 LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10880">
        <property type="entry name" value="MORTALITY FACTOR 4-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22732">
        <property type="entry name" value="MSL3_chromo-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02182">
        <property type="entry name" value="SAD_SRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00466">
        <property type="entry name" value="SRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51015">
        <property type="entry name" value="YDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YDG" evidence="4">
        <location>
            <begin position="495"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1012"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1020"/>
            <end position="1036"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1743008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1171" mass="132183" checksum="BF31E7CFACA97536" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DF01</accession>
    <name>A0AAD9DF01_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_005946</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DF01"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056149">
        <property type="entry name" value="PRP5/DDX46/KHDC4_KH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23469">
        <property type="entry name" value="KH_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="10">
        <location>
            <begin position="170"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="201"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="391"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="17"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="611"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="6">
        <location>
            <begin position="170"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="17"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="40"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="611"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="631"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1743325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="789" mass="86443" checksum="B434D39F2434B4AD" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGW1</accession>
    <name>A0AAD9DGW1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004459</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGW1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042039655" evidence="1">
        <location>
            <begin position="22"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="141" mass="16505" checksum="EBC8D978BE2B22AB" modified="2024-05-29" version="1">MMSRFLLQTFILAVLVSVASAFVAPSSQGNKSTQLMEKKWDADEERTQQQQFSFPNPLTEFADMWQNFDDIIDDFFNKRMGNGEVFYGQRKYKPSGKVTTEYNGYGFIDFKKIEAAREFREERARMKEEKLAAAQKEKNLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DH01</accession>
    <name>A0AAD9DH01_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Rhodanese-related sulfurtransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_004579</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DH01"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022111">
        <property type="entry name" value="Rhodanese_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020936">
        <property type="entry name" value="TrhO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040503">
        <property type="entry name" value="TRHO_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43268:SF7">
        <property type="entry name" value="RHODANESE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43268">
        <property type="entry name" value="THIOSULFATE SULFURTRANSFERASE/RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12368">
        <property type="entry name" value="Rhodanese_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17773">
        <property type="entry name" value="UPF0176_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="202"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="2">
        <location>
            <begin position="448"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1745288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="561" mass="62568" checksum="5326004D8624661F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DH40</accession>
    <name>A0AAD9DH40_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003544</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DH40"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="86" mass="9998" checksum="57E81D688644CE08" modified="2024-05-29" version="1">MGYSHHSSSSTSLPLFLTCAMCLSIVLVTQNKRRMRRRGRWQPTKRFLPVLVFNWIFGLFLGNRDADFCSQKPLTRSSSYSRQHST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHD2</accession>
    <name>A0AAD9DHD2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glutaredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_001829</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHD2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015038">
        <property type="term" value="F:glutathione disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03419">
        <property type="entry name" value="GRX_GRXh_1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000026">
        <property type="entry name" value="Glutaredoxin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011767">
        <property type="entry name" value="GLR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011899">
        <property type="entry name" value="Glutaredoxin_euk/vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014025">
        <property type="entry name" value="Glutaredoxin_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02180">
        <property type="entry name" value="GRX_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694">
        <property type="entry name" value="GLUTAREDOXIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694:SF18">
        <property type="entry name" value="GLUTAREDOXIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00160">
        <property type="entry name" value="GLUTAREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00195">
        <property type="entry name" value="GLUTAREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="334"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="Glutaredoxin" evidence="7">
        <location>
            <begin position="493"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="766"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="272"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="787"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1747866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="787" mass="84527" checksum="2D2FAE1B6C7BCF5E" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DI88</accession>
    <name>A0AAD9DI88_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002089</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DI88"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="69" mass="7498" checksum="3B8005FD252616C0" modified="2024-05-29" version="1">MMSLYQNHQESIATKKFSKFFPGKLRNMLDSVQGLGLAHGISWVSPASKPEPEEGAFGSTRISSGPSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJS3</accession>
    <name>A0AAD9DJS3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA topoisomerase (ATP-hydrolyzing)</fullName>
            <ecNumber evidence="3">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_001996</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterotetramer composed of ParC and ParE.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the type II topoisomerase GyrA/ParC subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1748033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJS3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009330">
        <property type="term" value="C:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00187">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.268.10:FF:000001">
        <property type="entry name" value="DNA gyrase subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.40:FF:000002">
        <property type="entry name" value="DNA gyrase subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.120.10.90:FF:000005">
        <property type="entry name" value="DNA topoisomerase 4 subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.90">
        <property type="entry name" value="DNA gyrase/topoisomerase IV, subunit A, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="entry name" value="Topoisomerase II, domain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="entry name" value="Topoisomerase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006691">
        <property type="entry name" value="GyrA/parC_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035516">
        <property type="entry name" value="Gyrase/topoIV_suA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050220">
        <property type="entry name" value="Type_II_DNA_Topoisomerases"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01063">
        <property type="entry name" value="gyrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004043">
        <property type="entry name" value="PRK05560.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004044">
        <property type="entry name" value="PRK05561.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43493:SF5">
        <property type="entry name" value="DNA GYRASE SUBUNIT A, CHLOROPLASTIC_MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43493">
        <property type="entry name" value="DNA GYRASE/TOPOISOMERASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03989">
        <property type="entry name" value="DNA_gyraseA_C"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101904">
        <property type="entry name" value="GyrA/ParC C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="Type II DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52040">
        <property type="entry name" value="TOPO_IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Topo IIA-type catalytic" evidence="9">
        <location>
            <begin position="127"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="8">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00063644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1748033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="929" mass="102301" checksum="2E610D74CC2B0C32" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DKC1</accession>
    <name>A0AAD9DKC1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ankyrin repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000889</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DKC1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24183">
        <property type="entry name" value="FIBRONECTIN TYPE 3 AND ANKYRIN REPEAT DOMAINS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24183:SF1">
        <property type="entry name" value="FIBRONECTIN TYPE 3 AND ANKYRIN REPEAT DOMAINS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="776"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="809"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="23"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="124"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="606"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="609"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="634"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="854" mass="95964" checksum="A5B1DD688623FF61" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DKK9</accession>
    <name>A0AAD9DKK9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA replication complex GINS protein SLD5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_001159</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GINS4/SLD5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DKK9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000811">
        <property type="term" value="C:GINS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11711">
        <property type="entry name" value="GINS_A_Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021151">
        <property type="entry name" value="GINS_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008591">
        <property type="entry name" value="GINS_Sld5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031633">
        <property type="entry name" value="SLD5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038749">
        <property type="entry name" value="Sld5_GINS_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21206:SF0">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN SLD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21206">
        <property type="entry name" value="SLD5 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05916">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16922">
        <property type="entry name" value="SLD5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160059">
        <property type="entry name" value="PriA/YqbF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GINS subunit" evidence="7">
        <location>
            <begin position="150"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="DNA replication complex GINS protein SLD5 C-terminal" evidence="8">
        <location>
            <begin position="229"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="60"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="256"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1749220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="300" mass="34138" checksum="8CDCE0E82501669F" modified="2024-05-29" version="1">MADLGNLLEEINNDDENIGNNEDQTYDCEDDLDNFDNQRSSSVPSALTAAVAQRRKLEDEKDETTGEDADGEGGRILDPDYEQLKSLWTNETASPELMPNDNEIVSIHVDVLEGQEETVDDLFQRSKQQRQSRDGGASGELASLVAQITKMDLDRTRFMLVDLARTRMAKIENHALHNRTMVDRMTEEEVAYLRQYGELIEKHYQRTVLNHMPAEGWKKLDDPEMIDSPDLEQFVFCRTLEPIEIDVSGEPNVLNEGEEEEDDDDDYGDNLQAHPAGAFLIVMYKKVRELIAEGKVQLLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-12-02" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6U3TB80</accession>
    <name>A0A6U3TB80_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Chlorophyll a-b binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_016457</name>
        <name evidence="10" type="ORF">SMAR0320_LOCUS3009</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated. Energy is transferred from the carotenoid and chlorophyll C (or B) to chlorophyll A and the photosynthetic reaction centers where it is used to synthesize ATP and reducing power.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fucoxanthin chlorophyll protein family.</text>
    </comment>
    <dbReference type="EMBL" id="HBGZ01004440">
        <property type="protein sequence ID" value="CAD9579161.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6U3TB80"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030076">
        <property type="term" value="C:light-harvesting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="8" id="KW-0157">Chromophore</keyword>
    <keyword evidence="7" id="KW-0437">Light-harvesting polypeptide</keyword>
    <keyword evidence="5" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042404957" evidence="9">
        <location>
            <begin position="17"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>3</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CAD9579161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1732919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="204" mass="21559" checksum="D6AA4E6498EF4881" modified="2020-12-02" version="1">MKVAATLVALAGVANAFAPAQNVNKGTALSAVEDMAGSTMPFKAFDPLGLATLGSDSTLAWFRAAELKHSRVAMLATSGYLVQAAGFHFPGMLSSDVSFETLSAMKPLDAWDAVPDLGKAQIYFTIFFAEVVSEAKGTHYTKGGDYPTIVFPNINFASSDPEKLKVQQSRELNNGRLAMIAIMSFVSAANIEGSVPALIGNPMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S1CU39</accession>
    <name>A0A7S1CU39_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PS II complex 12 kDa extrinsic protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_005749</name>
        <name evidence="3" type="ORF">SMAR1040_LOCUS141</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">FE60</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="HBFU01000206">
        <property type="protein sequence ID" value="CAD8926194.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S1CU39"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042409304" description="PS II complex 12 kDa extrinsic protein" evidence="2">
        <location>
            <begin position="26"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CAD8926194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1743128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="148" mass="16804" checksum="FD120896A88A6C0C" modified="2021-06-02" version="1">MMSNLSTLALLTATILAACLHETAAFSTCNSRISTANTQLHNSYDDEYEQPKEKKGFFANFFEELDAFVDDATSRRLGNGAQYYGKRKSSFYGKDDSNKKKDSTVFDPSEDYRGPSNAGYFQWLQDPETGEMKPVTRMKNKVVEKKMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XR82</accession>
    <name>A0AAD8XR82_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016966</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000072">
        <property type="protein sequence ID" value="KAK1732336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XR82"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="287"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="528" mass="56763" checksum="B27171DD0098EC41" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRJ2</accession>
    <name>A0AAD8XRJ2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Selenoprotein F/M domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_016787</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the selenoprotein M/F family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000065">
        <property type="protein sequence ID" value="KAK1732504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRJ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.50">
        <property type="entry name" value="Sep15/SelM thioredoxin-like domain, active-site redox motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038219">
        <property type="entry name" value="Sep15/SelM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014912">
        <property type="entry name" value="Sep15_SelM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08806">
        <property type="entry name" value="Sep15_SelM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Selenoprotein F/M" evidence="3">
        <location>
            <begin position="2"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="83"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="89"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="131"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="154"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="171"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1732504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="181" mass="20487" checksum="ED9C20AFF455FD78" modified="2024-05-29" version="1">MPILKSFLKDGEAESYQNVQVKFVPGRKAIMTIYESGDDDDEGEEESWVEKEQIVLSDYKTKDEMHALMVEKGFQLKSPEEVEAIQQQYKDEAEAERTKAEERREEMRIRREEMQRQREEKMMEDARAEVEGGGDGSSGGVSMGGLNRDGGVIVDDDDSSDDSSSDDSEDNEAKTDAKEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XS96</accession>
    <name>A0AAD8XS96_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016757</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000064">
        <property type="protein sequence ID" value="KAK1732545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XS96"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="207"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="540"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="612"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="704"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="17"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="91"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="832" mass="92990" checksum="499BC27FDB829F23" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSF1</accession>
    <name>A0AAD8XSF1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_016777</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000064">
        <property type="protein sequence ID" value="KAK1732565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSF1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1732565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="130" mass="15076" checksum="B2131BB80931245C" modified="2024-05-29" version="1">MYSSSEDEGSDDEASSVYPETMLDKIKRNAPGTTTLSWGFFLRNMNMTDDGWEELGRDVSHNTHLKNVYLNEASPSHVLCKQNQRQQNWFINETTTKNNNILYYDRLEWRSMSMSKSKARSNEQGIVAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSX7</accession>
    <name>A0AAD8XSX7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016428</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSX7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="849" mass="90716" checksum="28D5331E471E79A7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV90</accession>
    <name>A0AAD8XV90_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014744</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000038">
        <property type="protein sequence ID" value="KAK1734496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV90"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="124" mass="13855" checksum="930BA7582510AC52" modified="2024-05-29" version="1">MPHVEIPQAEFKTNSPPSSSSLILRNPNFVTKSIPVTSSNIPTKIQIWDVAGPTSTSTNSKSTNNSKSSVKGAHTAAKCYYSTSSAILLGYDVTSRSSYEEMRLWLNELRTSVHFMWWLWQLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVD7</accession>
    <name>A0AAD8XVD7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015066</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000040">
        <property type="protein sequence ID" value="KAK1734299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVD7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029455">
        <property type="entry name" value="GHL15"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45706">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45706:SF4">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14885">
        <property type="entry name" value="GHL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042051320" evidence="2">
        <location>
            <begin position="18"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="297"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="321"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="916" mass="98840" checksum="0264CA45B6BCAFB9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVY4</accession>
    <name>A0AAD8XVY4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014743</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000038">
        <property type="protein sequence ID" value="KAK1734495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVY4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="136"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="252" mass="26875" checksum="0C6E8F0802812A25" modified="2024-05-29" version="1" fragment="single">MVTIIIGNNEYNSNTSEAVPEYEVEQLAQALNVMYIPTSSKLDVNVTSLFQRVAEEVLVRRKRGVVAGAGDYGYSNGRQVKNGGLGGGLGGRYHSSGNGSGGGNNDTTRPSSPVSSKDLYGNNTSSSMMLPNDIMNGNNSSTHNNNDNDAMSTPSDKKKSNHKRRRSSNKPQNNKESSTSTSSTTTAEGCAGSVGAMISACTDADLKDENGEHKYDITMGDDEEDDVVHKNGEEDGENNGSFFMMCGPTTWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW02</accession>
    <name>A0AAD8XW02_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_014605</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XW02"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16448">
        <property type="entry name" value="RING-H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045191">
        <property type="entry name" value="MBR1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22937:SF65">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE ARK2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22937">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF165"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="804"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="109"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="210"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="332"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="334"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="367"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1734732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="858" mass="97090" checksum="4A166AC372521500" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW22</accession>
    <name>A0AAD8XW22_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_014803</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000038">
        <property type="protein sequence ID" value="KAK1734555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XW22"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045899">
        <property type="entry name" value="ATL71-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46719:SF7">
        <property type="entry name" value="RING-H2 FINGER PROTEIN ATL71-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46719">
        <property type="entry name" value="TRANSCRIPTION FACTOR C2H2 FAMILY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="202"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="156"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1734555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="255" mass="28245" checksum="4BBF7F95AF2A2306" modified="2024-05-29" version="1">MVACDNTSSISGCSYSGTSNSTLVGIIVGCIVGVLLLLLLIFCCRRERVLKVKTEDEETNLRRDSIAKIKESVDAVRDSTALNDMSNVTKGVLKRQIIDQLVIKKVQDDGSTGGTKKESFLQSLSKSNRAYSSFAAALSASSSSKVQFVDNDDNDVEKGDTTDMKNEEETEEPVVVDRRKSNAMARSLSVMLSSKKEDTSKCYLCLMDYATGDEVAFSKNEKCTHRYHKDCIVEWCMKRTACPCCREEFIESNTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXA7</accession>
    <name>A0AAD8XXA7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyltransferase (Family 32)</fullName>
            <ecNumber evidence="4">2.4.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_013757</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXA7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000030">
        <property type="term" value="F:mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051999">
        <property type="term" value="P:mannosyl-inositol phosphorylceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049625">
        <property type="entry name" value="Glyco_transf_61_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051706">
        <property type="entry name" value="Glycosyltransferase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007577">
        <property type="entry name" value="GlycoTrfase_DXD_sugar-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32385:SF15">
        <property type="entry name" value="INOSITOL PHOSPHOCERAMIDE MANNOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32385">
        <property type="entry name" value="MANNOSYL PHOSPHORYLINOSITOL CERAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04488">
        <property type="entry name" value="Gly_transf_sug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 61 catalytic" evidence="3">
        <location>
            <begin position="211"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1735594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="774" mass="88651" checksum="CA8B13015968F6C7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXR6</accession>
    <name>A0AAD8XXR6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding protein 42</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_014307</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXR6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12383">
        <property type="entry name" value="RRM_RBM42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050825">
        <property type="entry name" value="RBM42_RBP45_47-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034215">
        <property type="entry name" value="RBM42_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47640:SF11">
        <property type="entry name" value="RNA-BINDING PROTEIN 42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47640">
        <property type="entry name" value="TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="174"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="18"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="106"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="31"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="110"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="122"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="135"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="261"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1735241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="276" mass="30265" checksum="FA5EF66C8CC7D547" modified="2024-05-29" version="1">MDDDLDAFFDDVENAVKEVQEEEEATKSNNDSEPSSSAAAKDSSSSDNQTKIQQQQVGKEAADEQRPAKRVKVVAASSGAVKNIVASSAVSIAAPAVVQTAAPSMAVAAQPPPPPPPPPPSINNHDNNSQYYSGATNNNTTAQTTTTTQKSHIRAAAGQTWTDPTLTQWPENDFRLFVGNLAKDLKDHDLSQAFSKYPSFAMAKIMYNKTDGKSRGYGFVSVLDPKDCARAIREMNQSWLGSRPIQVKRSEWKDREWKEVQKRKRKDGRGKKHFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXT6</accession>
    <name>A0AAD8XXT6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GTPase HflX family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_013885</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXT6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01878">
        <property type="entry name" value="HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11060">
        <property type="entry name" value="GTPase HflX, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00900">
        <property type="entry name" value="GTPase_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030394">
        <property type="entry name" value="G_HFLX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032305">
        <property type="entry name" value="GTP-bd_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016496">
        <property type="entry name" value="GTPase_HflX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025121">
        <property type="entry name" value="GTPase_HflX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042108">
        <property type="entry name" value="GTPase_HflX_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03156">
        <property type="entry name" value="GTP_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10229:SF0">
        <property type="entry name" value="GTP-BINDING PROTEIN 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10229">
        <property type="entry name" value="GTP-BINDING PROTEIN HFLX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16360">
        <property type="entry name" value="GTP-bdg_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13167">
        <property type="entry name" value="GTP-bdg_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51705">
        <property type="entry name" value="G_HFLX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042050029" evidence="5">
        <location>
            <begin position="26"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="domain" description="Hflx-type G" evidence="6">
        <location>
            <begin position="415"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1735271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="673" mass="74640" checksum="F29D680E451D5580" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXV2</accession>
    <name>A0AAD8XXV2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GRIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_013597</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.60">
        <property type="entry name" value="GRIP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000237">
        <property type="entry name" value="GRIP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18870">
        <property type="entry name" value="PROTEIN TAG-278-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18870:SF9">
        <property type="entry name" value="PROTEIN TAG-278-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01465">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00755">
        <property type="entry name" value="Grip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50913">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GRIP" evidence="4">
        <location>
            <begin position="2198"/>
            <end position="2249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="678"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="757"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="816"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1542"/>
            <end position="1565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1898"/>
            <end position="1917"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="2268"/>
            <end position="2312"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="276"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="422"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="573"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="974"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1079"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1184"/>
            <end position="1211"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1285"/>
            <end position="1430"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1601"/>
            <end position="1780"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1815"/>
            <end position="1849"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="2004"/>
            <end position="2109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="117"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="690"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="717"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="758"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="773"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="822"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1542"/>
            <end position="1554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1556"/>
            <end position="1565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1906"/>
            <end position="1917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="2290"/>
            <end position="2312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1735891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2312" mass="257975" checksum="6563CEDA9B50BAC6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XY55</accession>
    <name>A0AAD8XY55_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013773</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XY55"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="141"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="229" mass="25323" checksum="AB960DFCCEF20794" modified="2024-05-29" version="1">MNHEPIIVRQSHQSMECTADGKGADFIATTILVMTADGVGKNDIHTVHDDDDEEFSTVVRGNCSSSSEMDMSRLPTWSSTAVMTASPPQFNGVVHLPTPIVDDLPGMIRSVSAGATSCDDDDTDTTDGDDTMDTETDDDQSSSSSSTVSSKVKGVSFNESVRVLPIPPLSHYTLEQRRNMYTNRFEVRENKLRNKKEYAFDNYDWKNCTEENSMLICPMSGNLLHPAHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYZ9</accession>
    <name>A0AAD8XYZ9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ASPIC/UnbV domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_012913</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYZ9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027039">
        <property type="entry name" value="Crtac1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011519">
        <property type="entry name" value="UnbV_ASPIC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16026">
        <property type="entry name" value="CARTILAGE ACIDIC PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16026:SF0">
        <property type="entry name" value="CARTILAGE ACIDIC PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07593">
        <property type="entry name" value="UnbV_ASPIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="Integrin alpha N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="ASPIC/UnbV" evidence="3">
        <location>
            <begin position="643"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1736313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="792" mass="87627" checksum="CFEACDB360941EB2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZ68</accession>
    <name>A0AAD8XZ68_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_013012</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZ68"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50031">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EH" evidence="3">
        <location>
            <begin position="137"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="291"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="523"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="346"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="14"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="59"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="291"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="574"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="622"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1736412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="631" mass="69387" checksum="A114FDD204C12AA2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0G1</accession>
    <name>A0AAD8Y0G1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0G1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31535">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31535:SF3">
        <property type="entry name" value="REGULATORY PROTEIN ZESTE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="427"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="597"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="346"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="597"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="631"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="666"/>
            <end position="690"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="708" mass="75446" checksum="32E3A718DF0F943E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y136</accession>
    <name>A0AAD8Y136_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012325</name>
        <name evidence="3" type="ORF">QTG54_012326</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y136"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="100" mass="11052" checksum="069264A77A6AB6A2" modified="2024-05-29" version="1">MMMMVRACLQSPTTSPHCPTRTHLNSSHRTLPGKPRNALKPLLQSNKKEGDVTRASMLAFNFAESSIADKTTKVVTTIMCKKKSITRSDLICLSLAVDYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1E2</accession>
    <name>A0AAD8Y1E2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_011983</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1E2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042105092" evidence="3">
        <location>
            <begin position="18"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1737116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="297" mass="32578" checksum="39D8104C7607C18E" modified="2024-05-29" version="1">MRTKSLEILAALPFALAFSPTAVRRSSPCSIIRHNLADVSVISNIHGRSASLTVSMASDDEAASSQSSAPKKKRKRKDGQNFSPPPASDVADDSSVEEAADEVIAAAAEPEEPKKTSVVMKVRDIRDIVSGAPEPAEVEEEEEVYVDDDKEDDELGDDEEWEYYDVDEDGNEIIVSNDDKTSDRTGDDSLEQLLADARSMRASTDRDAQQTEEETPIKDKIFDVISTIVTIDFFVVIGLLAWFLLGIFCSSVLKDDTVQILFNNNFERVTQPALGLLMIGSVAGSFGNKDEEEESYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y236</accession>
    <name>A0AAD8Y236_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cadmium/zinc-transporting ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_011903</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y236"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02079">
        <property type="entry name" value="P-type_ATPase_HM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000002">
        <property type="entry name" value="Copper-transporting ATPase 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051014">
        <property type="entry name" value="Cation_Transport_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48085">
        <property type="entry name" value="CADMIUM/ZINC-TRANSPORTING ATPASE HMA2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48085:SF5">
        <property type="entry name" value="CADMIUM_ZINC-TRANSPORTING ATPASE HMA4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="455"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="478"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="683"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="713"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1042"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="13">
        <location>
            <begin position="232"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="120"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="608"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="655"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="120"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1737617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1128" mass="122086" checksum="900E693CD717CC58" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y317</accession>
    <name>A0AAD8Y317_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_010557</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y317"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1738527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="587" mass="68340" checksum="1C05176E96CA7295" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y330</accession>
    <name>A0AAD8Y330_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ADP-ribosylation factor GTPase-activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_010972</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y330"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030100">
        <property type="term" value="P:regulation of endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08830">
        <property type="entry name" value="ArfGap_ArfGap1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46395">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46395:SF1">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="7">
        <location>
            <begin position="11"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="120"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="328"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="431"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="328"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="431"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="456"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1738303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="519" mass="52662" checksum="17D33DBEA1ACBD6F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3J7</accession>
    <name>A0AAD8Y3J7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010128</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3J7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="459"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="469" mass="52345" checksum="4FD0BB26670A7BC2" modified="2024-05-29" version="1">MPSQSNDAHSNTASPRRGYRVTGRAAHLRVARLFEALCDDHTTHDEQTRWIDTSPYANTAATPINNTNDTTDNNEPEISFLWENAPRYETKSIRDAVQVYSHLPNGINVLDDKWALARLMPSNCNDNDEALVTLESHCFRGSEGFVTFAKQYAWPPTLYKQRKCHVRVYGLLTSDGRAYVHKRAFLHVANEIFEYDSSSLLRVMVSRLKNTIEPIRGACCVGRKSAAYVQGGQANNGFEYLGLDFVLSSVPEEGDGHSTRRKPVAYLLEVNAPPSQDTATGLPHAEELHDEVISDLLRLWVLPNLGIKSVSKNGWECVYSPPISLDNGSSVDVEEPSNLIVPSKAAILNKIRWAMFERRTSKMYESSWRKEEAGVACSESDHPKSHKCESINGWNIFLESGGGAQVPRVVINAMTTSLMNRDRSIVGAKYLSEARKSIASLLAGSRSEKKARRKRRSDSYNGSECNVPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3T7</accession>
    <name>A0AAD8Y3T7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MAP3K-like serine/threonine kinase</fullName>
            <ecNumber evidence="7">2.7.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_011449</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3T7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF288">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="536"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="349"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="478"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="35"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="62"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="156"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="194"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="216"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="490"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1738155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="826" mass="91546" checksum="F4E4F4F70FEBEBA8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4A3</accession>
    <name>A0AAD8Y4A3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_010196</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RAMP4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4A3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010580">
        <property type="entry name" value="ER_stress-assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06624">
        <property type="entry name" value="RAMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1738880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="88" mass="9559" checksum="B70F242E953AB95C" modified="2024-05-29" version="1">MGKAAEHTDDPAISKGLIAFFMFVVIGSSIVQILRMFQTSVPNLRCLVLPPREQEEGSGGATSLEYIFFILSCSHNNHNSGRMSGGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4H5</accession>
    <name>A0AAD8Y4H5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010037</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4H5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="426"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="504"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="652"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="268"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="531"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="554"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="694" mass="73641" checksum="C9EBEC5B44ACBD1B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4U9</accession>
    <name>A0AAD8Y4U9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4U9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31424">
        <property type="entry name" value="PROTEIN CBG23806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31424:SF3">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="119"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="202"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="391" mass="43942" checksum="226A2F3597E7054B" modified="2024-05-29" version="1">MLDTAKEVEDSHDNKPKYGVKSKLWWDFIPIKNYVVPLLHTLIGIGNDLLDSLRDSVDNQIERISPAESRARSSLTTVEGTINETVAKRDAFDASADGKKLKSLKAKIRVRKQALKKLGSLQEEQQDTQQQADEANIPIDDYLDDVDTFVTDADNGDEITSEEEDNDDTDDNTDNNAAATDEESNTAPPVDDANTAAVTQQIQGKRAELAQFTTEAKALQAKRDKITKRLNQARQYVSRLKEKLSAWRSERKKKDGIESKMDKVLKEVGVEIQRYHGGSLTGKDILRVVANATEIFDAFAKIFKEHKRNGCVLDDDQIDNLCAGYKLTFLLWDGAFSHARKVNPSDHDRNMYTRYVKAAVHCHVAMGCSVTPKVHLMFRHVLHQMKNIEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y528</accession>
    <name>A0AAD8Y528_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y528"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010865">
        <property type="entry name" value="DUF1499"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34801">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34801:SF6">
        <property type="entry name" value="SLL1620 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07386">
        <property type="entry name" value="DUF1499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1739622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="194" mass="20363" checksum="ECEB670DE8EB4266" modified="2024-05-29" version="1">MKIVQTTALMATIATCQGFVAPQQSAAAQTALEMTSRRDALATSFATILAISVPSAANAIDACPKGSKNCLRQTWNPPSSTSAADAASQLRDVLNAYPQEGQEDGKVDGGGYTIISDSDGSFKLEYRSSGKGFFAKSFNAGKPFVDDLVIEPNGSSFEFRSASRQGDSDFGVNGKRLSYIGGLLKDKGWTGVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5A9</accession>
    <name>A0AAD8Y5A9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009627</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5A9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042018583" evidence="1">
        <location>
            <begin position="22"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="158" mass="17140" checksum="517ECDEED533F36B" modified="2024-05-29" version="1">MMNFQQLIVAALLLDFSTASAVETAVDSTHDGAASSATVPVRKRTHLRHLSSEEQNEMYDPFIGIPRELQADRLMRPHRVMSMPSASAMSIEQAAPSYTSSCPLDCGEEICAFSSPDSEPFCYPKCLPSFPVFSAAMESAEQAMSVSTALSPADHTMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y615</accession>
    <name>A0AAD8Y615_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_009329</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y615"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045103">
        <property type="entry name" value="RNF5/RNF185-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12313">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="518"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="14">
        <location>
            <begin position="124"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="246"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="307"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="452"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="11"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="105"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="308"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="321"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="365"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="452"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="464"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="485"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1740379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="537" mass="58139" checksum="F08F69C6EC2D1D65" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6C5</accession>
    <name>A0AAD8Y6C5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008578</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6C5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042056255" evidence="2">
        <location>
            <begin position="19"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="332" mass="37065" checksum="5693565CBFED7F7E" modified="2024-05-29" version="1">MKSKAIAILATLVIRSLAQDDVRELYRGGGGGGRGGGRGGRGGGGKGKDRVERLFKANCYWGEDESTPLISRINEKCDGYDCMGFTECLEWETIEDDILIEGCDDDMSKEYASDLKDTINTALQVKREKFKEMSIEDRANYRQQKEDMQQRNAENVMNCGCCADNPDFQLGELVDKIEGAVAKTLGFDTPKGDSVTCVGRLQAMVDAKCPDFISSCPDEAIDIGRECILEKPERPNVDWAGISLQDTIEWKEQRNEFKTQVLKCSCCTGIPVAVLFGDTSAESEEETEVEANELLGIITEDEDRPSSSKIQLTIPLPNRPYRPHRRRQQFQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6T2</accession>
    <name>A0AAD8Y6T2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Nucleolar GTP-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_008788</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6T2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01897">
        <property type="entry name" value="NOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1190:FF:000001">
        <property type="entry name" value="Nucleolar GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000496">
        <property type="entry name" value="Nucleolar GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024926">
        <property type="entry name" value="NOG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041623">
        <property type="entry name" value="NOG1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010674">
        <property type="entry name" value="NOG1_Rossman_fold_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012973">
        <property type="entry name" value="NOG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45759">
        <property type="entry name" value="NUCLEOLAR GTP-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06858">
        <property type="entry name" value="NOG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17835">
        <property type="entry name" value="NOG1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08155">
        <property type="entry name" value="NOGCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038919">
        <property type="entry name" value="NOG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="OBG-type G" evidence="7">
        <location>
            <begin position="169"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="386"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="508"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="521"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="552"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="591"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="632"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1740693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="721" mass="82409" checksum="246DA4178CD59638" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7D7</accession>
    <name>A0AAD8Y7D7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nuclear pore complex NUP2/50/61 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008633</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7D7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015007">
        <property type="entry name" value="NUP2/50/61"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08911">
        <property type="entry name" value="NUP50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nuclear pore complex NUP2/50/61" evidence="2">
        <location>
            <begin position="5"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="204"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="390" mass="41680" checksum="1D1A7A9AB678EE86" modified="2024-05-29" version="1">MPKLKRTSENQITKDTYDRGEDESRFPEEPDPGFGMTRADPDVIKRRKIRKASRKFAAPSSSAPPKAPAATNAFASTKLVANDAPSPSSNPFAKVQLNSGTTAPPSFSFGAAPKAEPKPFSFGPSTSQQQSSSKKSSLPSSKPTVKNTAEIEKINKNFFQMIRDHVDKGQICTNLSSLMDQYTNVAEQLEDDGGDGGNDDDDNNNGGSAFSGGSSNNDENNNSQPSSTSFSGFSFASSPHLLSSGATTFSFTGGSAPAPAATTMSNSSFSFGAQPATTSGGSSSNPIASEDDPTSNPDDGKLDIGQEENKDEETPYQVQARLVKLEGSGNTQAWKKLGTGVLRLYRNTITDKKRWCYEMELAKSCLTSELAKECHSKRSHGKQKRGKYGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7X4</accession>
    <name>A0AAD8Y7X4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7X4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="367" mass="41260" checksum="5AAD2AB4691788EF" modified="2024-05-29" version="1">MLTSPKVFNYPIPGNPTGGILHIYGEAAAAQDVILYCGGFPDGLEPISNLAERLATTRDGQARGCYFGVTCFPGFDNKTFNEQKFTGYKKSGFTFDEVTCCVRDAADLLFKEHAKSVSSSTDECKTAFTLMTHDWGVVIGHLFINRAIEERRFTQHKPDRLVMLDVLLLPHPKSNYKEMLRGKEIQKPTARDNLLSLSYRIAFAMSFAVLQFSEAVGLIVLAVLTTIVFSILKLNPLQDVDKLLGRTKDLKHFLYMTYPYYHMFKEVLKGSETVFDVATLPLDLKETPVLYMYGAKKNVMFHDNRSVALLEREEKEGLSESRVVRLEESGHWMYCQEPEVCENEIRKFLKGGGGGGEASSGDTQSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7Z3</accession>
    <name>A0AAD8Y7Z3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mpv17/PMP22 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_009190</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7Z3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF104">
        <property type="entry name" value="MPV17-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1740240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="255" mass="28587" checksum="0B1C9D97CE8FDEDA" modified="2024-05-29" version="1">MALYQRVGKSLLLSPRSASSSPIVTATSLARRARFLSTEAAATPASTTAKRKGFVEWYEGHLNARPVLTKAITGACLWGLGDVVAQVVPTLIQDEDGDGDTTKKEFKYDIPRTARAVTFGFVIHAPLSHLHFNLLEWMTVKGGFTGLSIPIFKTVMEQFVYWSWFSNSLYHGAMGAMQGKNLDEIQNRIKDVLWGTQLAQWKFWIPVQLLNFQFVPVRHQLNVVLLTSVVWTALLSAWYPPEEEAEGEVSEEKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y956</accession>
    <name>A0AAD8Y956_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y956"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="869"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="950"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="950"/>
            <end position="971"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1142" mass="129128" checksum="1F43ED1D211E948D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y996</accession>
    <name>A0AAD8Y996_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y996"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042143410" evidence="1">
        <location>
            <begin position="21"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="243" mass="26409" checksum="CCE044D2C03F2F36" modified="2024-05-29" version="1">MTSTPFFPILLLAVLGACECFTGIGTPLSAAKRRSCIFAALLEEDAYTKSFLTIDKCAFAGVPSDDLYDAVRYVDRNASKLYPDESAKGDMWKRACGSWKLQLATGPPARGGTTPFKTVPIFAYAMIDENNFGNGVGINQDTIILSLLGPHYFNTKRRVMGIGIEDMFLFSNKVTQFLPEFISGGMGLKKKPTDFSNKKGSRMPAFTIIGSSEKSLIARGGSGGIAIWTRLDKDIRPAAYGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YA06</accession>
    <name>A0AAD8YA06_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GPI inositol-deacylase</fullName>
            <ecNumber evidence="1">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006938</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GPI inositol-deacylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YA06"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012908">
        <property type="entry name" value="PGAP1-ab_dom-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47909">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47909:SF2">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07819">
        <property type="entry name" value="PGAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0653">Protein transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="GPI inositol-deacylase PGAP1-like alpha/beta" evidence="2">
        <location>
            <begin position="251"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU365011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="462" mass="50145" checksum="A1F40BD1FC606B92" modified="2024-05-29" version="1">MHDTLIQAHDAIVKGSGYAGGLHLTQQYCDEVDAYIDSMEREKAVAKQNNQIEEKDADPIGIDLYEQISKWTPIEDGSTRGNVWAISMTQWNCMADPALVIVTFMRTEQSGLSYTCDYCYNSSASCTIGYVEGLTLNTFRGNNLHPLALSAKIEASPTIRINGALESEQNCNQSTKKKVAVLLCPAQFCVPVDYAELLDTIQSELTNVDVVATKVAPLPRTEWIKVAKQLPTKNFIDANLSVKVTLDWYFDAIESALTELFAEGGDDTEICIIGHSIGGWVARAYLGGLSGSSTSVYRLGREQIKSLVTIGTPHISPESALVDQTRGLLREIATSDECSSQALSERGVTITCVGSSSLAGKLITTDVEELIAATSYLPLVGKLGDDVKGDGIVPTELAFMESPARRVEIEKCSLSGSAVRHAHVLPTPWNLVDGNAASIKLPEDIVWYGSPGVLSQWLKYIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YA41</accession>
    <name>A0AAD8YA41_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YA41"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="172" mass="18807" checksum="1D79B81D13BA35BB" modified="2024-05-29" version="1">MSTNTKKRGLSPAAPNVDPTAAAAAAAAAAAIDKPAKKPRKKAVTAKSLGLTKDEFESIKAAPIKRTLKDIVKKLAEQVDEDWHDGYEDQAETKGEWFEAIQEPLQAVLDIGVGKKTAFLQCNEVLKIVSDSFYDLLACPCRCDTKDELDEMDRSFELQLPWGETDYMATSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAI6</accession>
    <name>A0AAD8YAI6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007627</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAI6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="46" mass="4941" checksum="B87739692FB00687" modified="2024-05-29" version="1" fragment="single">MAKYVGESAAEVAAASNTSTSTKKPTDPTQFYSSQIPCDHLFCLWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAJ9</accession>
    <name>A0AAD8YAJ9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006493</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAJ9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="159" mass="17902" checksum="09F34B1557CD3561" modified="2024-05-29" version="1">MSSSLRKNNATNTTTFTPAPTPAGTSKPPNSTGQPTTTKIHTHEPTKKYIPPPDDNDDNTDNNKSDEKNKRKNTGVTIFWTLSCLAIAVFFLFYFRNSIAFFLGNLWTNTQRYGCKGFMHSLFPCFYRGLSGGHQPLDQIIFETDESSHTRSNLREGLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YB31</accession>
    <name>A0AAD8YB31_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006772</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YB31"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009858">
        <property type="entry name" value="DUF1415"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07209">
        <property type="entry name" value="DUF1415"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="260"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="334" mass="37322" checksum="7E86D3C3304A6D65" modified="2024-05-29" version="1">MKHAEEESGCHSSSSSSSDESSSSSNYALHDTSTDDDDGSPEQRQVKKWTLQIPIGLGLCPWAAKSHNQGNLRYVTYTSETPHDVAVCVQREIQRLVVKNHNHHYDSITPPWSTTLVICPYVKEWNESFPTFDRFVSHDIWDQFEQDDNDESNTSISDDITLVAFHPNFLRWHGLPDNIKEGSVVQSHYGIIGKKSVETATATVIETCNKAFGMRKVKVRFHNEETNESAACNARRQEQYVPTDWISLHASNIREGIEGGNNSESNSGSASSAPSQQGTALADNAMHQAPYPTIHIINNADLASLSIRDISRVKRKNAHRMMKLGWDGVEEKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBK0</accession>
    <name>A0AAD8YBK0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_006997</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBK0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1742432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="188" mass="21096" checksum="D701A118ECB4B828" modified="2024-05-29" version="1">MICPSSLPPSHHFPTRYPLPLELAHQSYLNWQPPSLQSHEVAKDCVPAEVLAAYLDGSNQKKWNEDKVLDINISRTGSGLYRQDMVLKPQRVLTGKTTIMRYTQKICVDKIGNSNYNAFVELDTKSKSNTKLRPFHILKVNVGIEQVGNDVHIYAAGIMKVNRKIVPNLVIFARAAGRKVARALGVYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBV2</accession>
    <name>A0AAD8YBV2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005903</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBV2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1743282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="312" mass="35055" checksum="3ABCF1533F6EC2D1" modified="2024-05-29" version="1">MEPSFFSMEHETSTRKLTTEEHAMWPRSNFEDTSPIFLKSPLTLSNLLTQTSVSQSRTTSKEEGAFNRSLPRVEHGRTIPDIASSTSGRQYSLEKVFEVDGRQGIATNGTHYFVSSSTALFMYDLEGNLLHRNDNPFDALPLPAKIILETSAILKGNFTRELSGLMQDVVKIFKLPYYSRSVAWNADSGQVECSAIAIDVDNELVWMSDWVNSNYVYKATPEWTQGLAFYKGDLFITADDGDADRKEPDNLWFVPKETLLNNATYIGLEKAFDVPPFLDHGEIEDDSACKQGNAYCTWNAPGLLSRIYKGDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCH5</accession>
    <name>A0AAD8YCH5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005224</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCH5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1743627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="69" mass="7677" checksum="9DBFC85F2273416F" modified="2024-05-29" version="1">MILSIASTTVVAAATFAWLFPYHGWSKETHDLMQTLNDEDTDHTHITAGKLKEAVAKLPNVVQKWINAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCS3</accession>
    <name>A0AAD8YCS3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_005455</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCS3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="478"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1743858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="526" mass="59067" checksum="86806C8D9F65A1AD" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD67</accession>
    <name>A0AAD8YD67_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD67"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02980">
        <property type="entry name" value="TRX_Fd_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01257">
        <property type="entry name" value="2Fe-2S_thioredx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042178813" evidence="2">
        <location>
            <begin position="18"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="216" mass="23005" checksum="B9418C63E9C7DD8C" modified="2024-05-29" version="1">MTKSILVMLASAQVVSGFSLTTTQLRTPTQIHSTITSTTSEEVVVKTQVPVSRISVCAGELCQCQGEEYEYTGGASDAAVKELRQLDFKFPIDEVGCLGACGMGTMIAIDYENGDSIMTDGLESTYTELGISASTQSQSSVDGSEQSNDIVEATSSAVVSDATTPTATKKKPSAKELVDVRERMRQESADVEVENPWLKMGGYLAKKATSKLFGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YE22</accession>
    <name>A0AAD8YE22_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YE22"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="194" mass="22244" checksum="E588D5B67EB3E7C6" modified="2024-05-29" version="1">MTLQYSNLPQEQPPMPAAQSESLLEDWPRRASSTDHEQAAVSQSQSRVSFSEFSSLCVYENVEDLYLKKKAYSQKDREVFSARAMMEAIRIKNLIFNSPPVSVKDSIKYLLKNNIISRDELIGIDHLIAGRRTDALHVRRDHMAAVLRKQQEQRRHQPQLEEDSLIIELGRFSEQSSLRSTHYAIARATLSCSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YF80</accession>
    <name>A0AAD8YF80_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YF80"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051044">
        <property type="entry name" value="MAG_DAG_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11614">
        <property type="entry name" value="PHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="1">
        <location>
            <begin position="89"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="373" mass="40635" checksum="1F55D444DEADA171" modified="2024-05-29" version="1">MTKTPTMLDNSPNESPCSQLAFGGNGGSVLRLISASSQCPFKTSDGVLLNVECFGPNYGGGGIDNIHASTADHSMHKRSMHNSDEWPLLLYVHGVCESAETWGVQTLVQYCAKHCWRLIVLELAGHGLSENKAGLGRATCPNFDDLVNHVVEFAEQMSGKFSRSRGFAMCGCSLGGALVSFAVRGILATRRDKTEQHEHPDFYGIALLAPSLGVNPGAIPPSPVVTALKALSFFLPSHGVLTPIEHPTYACPPNSRRNFSGRWPLSTSSMLLDLTSNRVPNDVVSGNVQQTMEGLPSLYVLMGDKDEIVPLQSVLDWFDAVPLSSDNGEKMLTVLKGAGHGFFHERLKENKKKKTAFDHLFEYLNRCAKKDFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFP1</accession>
    <name>A0AAD8YFP1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Iron/ascorbate-dependent oxidoreductase family protein</fullName>
            <ecNumber evidence="2">1.14.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005113</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.-.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFP1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="1">
        <location>
            <begin position="352"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="510" mass="56443" checksum="C863914DD3F5D4DC" modified="2024-05-29" version="1">MAPIAFDNIDEAPSSPRTAALYYWGGGGYNDDDAAADCNVNNHVQSQQKSDVSTLREYTTSGGGRHHHQRHHRRPVIKFHLEMDDDCNHWMFLRRPAPAQVSSSAAADTNSVQANSLQEDNNNSELLQSQNLVKQVPAAAETAEVDINSDGDFNTIPIINLDQPLEKYAKQIGDACRDIGFFYIVNHGIEECIMSDVMDASKRLFDLDLESKLALNAGNDGKEKKGYRGYFGIGAEDLDNKDGTRDLASEEQNGLNKMLKSKGDFKEGFDVGLEKQDMNVEGGDNACHAFFGRNVWPNEHKHESVIGFRQSLLRYQNELLKLADKLMIAFAMSLQIDDGAAGLPMDYFLTRTRNPMCTLRLLHYPPSLDMANSGCGAHTDYGLFTILQQDSIGGLQVRNHAKKWIQAKPLRGSFVINVGDMLSHWTSGVYASTVHRVVSPSSSSGYHRYSVPFFFNPDHDAVVEPILNDESGDGDDCGGDGGICSCKKRRNSSALEILQARYNGTFQSDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YH08</accession>
    <name>A0AAD8YH08_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ZIP family metal transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_004576</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YH08"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16950">
        <property type="entry name" value="ZINC TRANSPORTER SLC39A7 HISTIDINE-RICH MEMBRANE PROTEIN KE4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16950:SF16">
        <property type="entry name" value="ZINC TRANSPORTER ZIP13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="203"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="400"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="444"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="473"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="509"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="89"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="238"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="90"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="238"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1745285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="532" mass="56997" checksum="DC67C52CC3444DE7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YH17</accession>
    <name>A0AAD8YH17_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_003046</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YH17"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="161" mass="18127" checksum="EDEE1B3B187408E7" modified="2024-05-29" version="1">MKLDQIYYTKATPSKRFVAIPNSVNYHLMKKYYPFSLASNERKRPRTDPGLTYGTQLSSLVTSFRPHTPGLLAEPHYEHVQPTASMRLQPTKRGEACSLLSSLRLANRIAPPPPNNDVRHDINIIADNSTEIDLQWSDSSETMQLYSTNESSPDESTGQSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YH57</accession>
    <name>A0AAD8YH57_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_003058</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YH57"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040053">
        <property type="entry name" value="JOSD1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006155">
        <property type="entry name" value="Josephin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13291">
        <property type="entry name" value="JOSEPHIN 1, 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13291:SF0">
        <property type="entry name" value="JOSEPHIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02099">
        <property type="entry name" value="Josephin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01246">
        <property type="entry name" value="Josephin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Josephin" evidence="7">
        <location>
            <begin position="5"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1746451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="305" mass="34984" checksum="3E1DC9EA671C245B" modified="2024-05-29" version="1">MIHEKQERQFCAIHAVNNLLQLPKDSYYVESEGVGPSYESSHHQHVINEWRCHGRLIFRQQRLRGNQSPAINSDQNNASGSSEKMNLSVVATQSEFNDIAEEITNRELRLMEGNDPMIADSNDCTTEKQSASTLSTFQKFRSKHFTPNFGNYSYEVLETALSRRGVTLEYYRVAADTSESIPDTLLDKKQNIIGFIVHEEETSADSLSYLRRLGSHVPIIRNICKGGRHWWTITGVKRSCYLSDSSNNKTRVRVKEQKEDSKKWYLIDSNLDYIQTLSSDDDLMSTLRDMQSRGALIFCCHVTQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHK1</accession>
    <name>A0AAD8YHK1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHK1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026893">
        <property type="entry name" value="Tyr/Ser_Pase_IphP-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13350">
        <property type="entry name" value="Y_phosphatase3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042044985" description="Rhodanese domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="305" mass="34111" checksum="F0741621A6FB3E4F" modified="2024-05-29" version="1">MVAKISSLVLLTISTSSALVSRPSFKIPKSYHGLCTPPMASSTRLSVNTDDIDVSTVTIPTKTAEEEEFDAHNAALCKERNLPLEKVKNARDLASTENSPIKPGRVYRIGRVSDATEQDLEILYGQIGVKTLVDLRSPTELRDDPTLEREEVFAGFTDMVFYENGNKVKELGPEEKRMQKISKRDKLKKAVSGAKKNTKEVVVGFVDNFFGGDEFDGEEKEEECIDCMEASKLLEESSRRKDRKERHFVSIMNELKYVRGTLSKLRKRDIAGTILKAPSTIVSKSARENIKNLSSKRLMEGVCPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHZ6</accession>
    <name>A0AAD8YHZ6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003749</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHZ6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="387" mass="45758" checksum="3905B4DC8C38645C" modified="2024-05-29" version="1">MFLNLIHADMKNESDRDNGHRHRKRSSKRHRKHSNHRRQHEEHGIIRFCINYVCCQTKKRSSQILIAAFYLWLMAQFYYFFFYDLKDYLAANTKELYDEFFAPTDDRRYSGTSGYITNDYFHDYSNQYTKKMTPEEMTRLRKERIKEARKALGSAAIVEDEEDDDGFDKEGYMKDSGGKRQQNNRSRRNRKKKSRDEEGFTKKESLKEGCSPLKWHSYHFPNCNEVHEIDLRAVVRHPRENFIRQTTAAAASDDTPANASASFPWGFVSNGLWRDVFSCDPREEVTSSFESPISPMPPAVLKIMKREHEYDQRNFQRHRRDALVMERLSSSHHLVPIYGYCANTVLTQAISHTLDDVIYARENEQKKKWNPERLPNQASVRIMDGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJT9</accession>
    <name>A0AAD8YJT9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA-directed RNA polymerase III subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_001661</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPC7 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJT9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006383">
        <property type="term" value="P:transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024661">
        <property type="entry name" value="RNA_pol_III_Rpc31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15367">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15367:SF2">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="202"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="87"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="202"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1747698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="261" mass="28156" checksum="309B3D066928CC8C" modified="2024-05-29" version="1">MSGRGRGRGRGGGGGPRSASQQYLLSSAQEAGFDVRNLRTSSTGMFSDFELHSSGERRLHQHETKVGQQMADVGAVISAGVKQEPGSAAAPSSSVAAASTEQPRSPETIYLISKTRELHHKFQSSVFYVRSAKLETMPDVVRYSDRLRPPSNVDAGAVLSHCLGGRKRTLGDHGGVFVPEELCGGQRRVRVDEADAKKLKGIDLDDLDDKNQKDGDDDEEKDEDEDGFHEDDGEESEGADYVANYYDSADESGGSDGEPTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YK43</accession>
    <name>A0AAD8YK43_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Retinol dehydrogenase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_002174</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YK43"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF148">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041994885" evidence="3">
        <location>
            <begin position="27"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1746830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="427" mass="47650" checksum="86D68DB4F8169EE3" modified="2024-05-29" version="1">MMRRRMFCVIILEVLLLISSLPKSAAFGLGNAPPGLSHVDIVQLLKRNPYSHGSNNNNGCDINPLKGSTAVVTGAAGGIGGEIAKIIHRLGGTVVALDRDVAGLEKLKDTLDDEERSREGLISNESRVWVLPTQHQDLDSVSHSANQIIDRFDRIDFLVNNAGLTYRDDFICGDERMKATSGQDLLFTVNYLSHFLLTEKLLPNLSRAKGRVVHLTSTYHWKVDGSEIIPGDAKCPQAYEFDPSSQSTKHIERSYGNSKLAQIFHSRSIHMHAPDCDSVCACPTWAATGIGGEDARDFLSMMAFPIEGSNEGETATTKIEEIRYGPGITSAINAMFRPREELGDALNCGRSFVANSRTLEFFVFRNSLLRWPIWRDGLTDLLGFLLLLGQRITYEDFIIQETSPESQDEEKRSQLYNWSRKEVQEWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKT9</accession>
    <name>A0AAD8YKT9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000373</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKT9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="258" mass="29432" checksum="C76957E96432C061" modified="2024-05-29" version="1">MKNAPIPAKKAQPMVDPQRQEELKKLIVKCLLRNELLPENTGISSSGRDKVLTLQREDPSLASVGEQQQEQQLPITRDPPEESYCTVRQPESQDVRTVQYPRDVLSQPPRPEPPQSSEPPQSYYPVRQPESQDVRTVQYPRDVLSKPPRPEPPQSHYSARQPGMVQYPRDVLRQPPRPEQVRYQIYSPNPQPPTSVCTAPVQNDLYSSQKSACANMSCRSIQSQNHIIGESGLSSHAMDRRRYYKEMLLQQQLTQAQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKU0</accession>
    <name>A0AAD8YKU0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyl hydrolase (Family 16)</fullName>
            <ecNumber evidence="4">3.2.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_002534</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.-.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKU0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF24">
        <property type="entry name" value="GLYCOSIDASE C21B10.07-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26113">
        <property type="entry name" value="GH16_XgeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="301"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="3">
        <location>
            <begin position="502"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="427"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="466"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="491"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1747190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="830" mass="92814" checksum="87CF71C29599C7ED" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKZ8</accession>
    <name>A0AAD8YKZ8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tc1-like transposase DDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002360</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKZ8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="238" mass="27403" checksum="14012A5FD8866C44" modified="2024-05-29" version="1">MTRKKGSTTAYQAFTPRNEYLYDCFISYNFPAGIRNVPRRFLMDGDECSFQVGDIGQSYGHAVKGLRVRKMGNYGRGASKIVVIMFIEPGDPSLDPTELGSIARPRIWYRVSKDKGTSSDAYESFLDNYVLNKMRPNEPMRYLMHDNLPSHKTDAVFARIHNAGHEVICRPPYRPHIAPIEFAFNMLACSLRDRWEQIKNEEQLIKAIHEIIDNRIGMGGFDELFQRCGYRYDSEEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YL64</accession>
    <name>A0AAD8YL64_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cell division protein FtsZ-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_002480</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FtsZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YL64"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048285">
        <property type="term" value="P:organelle fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02201">
        <property type="entry name" value="FtsZ_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000001">
        <property type="entry name" value="Cell division protein FtsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00909">
        <property type="entry name" value="FtsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000158">
        <property type="entry name" value="Cell_div_FtsZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020805">
        <property type="entry name" value="Cell_div_FtsZ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024757">
        <property type="entry name" value="FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00065">
        <property type="entry name" value="ftsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="CELL DIVISION PROTEIN FTSZ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314:SF3">
        <property type="entry name" value="MITOCHONDRIAL DIVISION PROTEIN FSZA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12327">
        <property type="entry name" value="FtsZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00423">
        <property type="entry name" value="CELLDVISFTSZ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01135">
        <property type="entry name" value="FTSZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042227135" evidence="5">
        <location>
            <begin position="20"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="6">
        <location>
            <begin position="107"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="7">
        <location>
            <begin position="303"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="427"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="441"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1747136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="470" mass="48853" checksum="C744EB50EDCE8F7D" modified="2024-05-29" version="1">MAAMAILASCFTATTTTCAFAPSTSLLQKQSIIITPASSLRAFSDNNIEGEEDISFVSAVASGWQPERGSFAGITRRNTKTSSTALGMLDDYDAYAVIPDGGLSPCVIKVVGVGGGGCNAVDRMLDTRVSGVDFWAINTDAQALGRSKAKGARVLNIGTAATRGLGAGGNPEVGQLAAEESRAEIAAMVEGTDLCFVTSGMGGGTGSGAAPVVAEVSKEAGALTIGIVTKPFRFEGKRRMRQAVAAIERLKENVDTVIVVSNDRLLDIIPENTPMNRAFAVADDILRQGVVGISEIIVKPGLINVDFADVRSVMSDAGTALMGIGIGSGKTGAEDAATAAISSPLLDSSIDNAKGVVFNISGGEGLSLTDVNRAAKLIYDSVEEDANVIFGALIDDSLEDSISITVLATGFADNTKQNLGLLNDVVSRPSAKSTPPPPVYVEEEEDEPEEEQDDGDGRVPSFLRTLKRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLA2</accession>
    <name>A0AAD8YLA2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000610</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLA2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="496"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="584"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="550"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="662" mass="75504" checksum="232C9177B87EB195" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLD5</accession>
    <name>A0AAD8YLD5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sulfotransferase family protein</fullName>
            <ecNumber evidence="5">2.8.2.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_002585</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfotransferase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.2.-" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLD5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11783">
        <property type="entry name" value="SULFOTRANSFERASE SULT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sulfotransferase" evidence="4">
        <location>
            <begin position="22"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfotransferase" evidence="4">
        <location>
            <begin position="167"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfotransferase" evidence="4">
        <location>
            <begin position="250"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="126"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1747241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="391" mass="44321" checksum="D82DFC50C8580553" modified="2024-05-29" version="1">MPLLPISSPSTISACRELPLRPSDIFICSYPKSGTTWTQHIVLTLLLADRKYKIAASTPCDSDAGKDDLAYNHVSDYAPFFEIDAHWQSSPSTNSTKVLADSVRENHDRLGRRVFNTHLRWDMLPKRREVDGSTPQNDDKEGNDDVNTGPSDDNDSYIHKERPQCGKFIYVTRNQIDVVASFYHHLSNQIEGTYTDTFETFLRDWMDGKIPFGSSLHHLIGFAGGFADNLYDTSRGHDDIGDDESTGVTDQPLLLLSYEKMKSNLRTEVLRIISFLNLTHIPSHVLEEEILPSFGFSSMKNNIEKFQPKSVGWLNGFQFLRKGVTGDGRRLLLNRSTNNSGGGKEEGESSELMVAYNDWVEREEYRSKISNVLRGDCYEDCREVFLSVVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLS0</accession>
    <name>A0AAD8YLS0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ankyrin repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000865</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLS0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24121:SF32">
        <property type="entry name" value="DEATH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24121">
        <property type="entry name" value="NO MECHANORECEPTOR POTENTIAL C, ISOFORM D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="792"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="29"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="371"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="539"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="146"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="193"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="376"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="543"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="570"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="605"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1274" mass="143150" checksum="471D297DD77F1081" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YM59</accession>
    <name>A0AAD8YM59_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Kringle domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_001090</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YM59"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004175">
        <property type="term" value="F:endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005102">
        <property type="term" value="F:signaling receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00108">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.20.10">
        <property type="entry name" value="Plasminogen Kringle 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000001">
        <property type="entry name" value="Kringle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013806">
        <property type="entry name" value="Kringle-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018056">
        <property type="entry name" value="Kringle_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038178">
        <property type="entry name" value="Kringle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050759">
        <property type="entry name" value="Serine_protease_kringle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24261:SF7">
        <property type="entry name" value="KRINGLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24261">
        <property type="entry name" value="PLASMINOGEN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00051">
        <property type="entry name" value="Kringle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00018">
        <property type="entry name" value="KRINGLE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00130">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57440">
        <property type="entry name" value="Kringle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00021">
        <property type="entry name" value="KRINGLE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50070">
        <property type="entry name" value="KRINGLE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0420">Kringle</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042107850" evidence="4">
        <location>
            <begin position="27"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="domain" description="Kringle" evidence="5">
        <location>
            <begin position="214"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="28"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="182"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="298"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="31"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="299"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="319"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="336"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1749151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="658" mass="73928" checksum="69D0A4CB0E79927A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMK9</accession>
    <name>A0AAD8YMK9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000712</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMK9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="353"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="684" mass="74001" checksum="C938657D16B16747" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YN35</accession>
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    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000284</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
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            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="522"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
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            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="525"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="553"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="579"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
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            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="659"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="689"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="714"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="767"/>
            <end position="776"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2121" mass="238183" checksum="4A2EA9A0385E4093" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YNF9</accession>
    <name>A0AAD8YNF9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein bL17c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">50S ribosomal protein L17, chloroplastic</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">CL17</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_000245</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial ribosomal protein bL17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YNF9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1030.10:FF:000001">
        <property type="entry name" value="50S ribosomal protein L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.10">
        <property type="entry name" value="Ribosomal protein L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01368">
        <property type="entry name" value="Ribosomal_bL17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000456">
        <property type="entry name" value="Ribosomal_bL17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036373">
        <property type="entry name" value="Ribosomal_bL17_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00059">
        <property type="entry name" value="L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413:SF16">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL17M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413">
        <property type="entry name" value="RIBOSOMAL PROTEIN L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01196">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64263">
        <property type="entry name" value="Prokaryotic ribosomal protein L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 7 8" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00072708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00077677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00082728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1748306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="158" mass="18315" checksum="D728EA295409EB04" modified="2024-05-29" version="1">MRKRLAQFRKLGRTPDHKWAMLRNMVTSLIKHERIVTTLPKAKELRHLADKVVGYAKKGDVHAKQLALRVVREKPMVTKLFEVMGPRYEDRDGGYTRVMKLSRPRRGDNAPMAVIEYVDRPGEIRAARVPEKRKQKYFNNLGEVLEHAGIKSIESQQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YNI2</accession>
    <name>A0AAD8YNI2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cullin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_000539</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the cullin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YNI2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031461">
        <property type="term" value="C:cullin-RING ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000050">
        <property type="entry name" value="Cullin 4B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1310.10">
        <property type="entry name" value="Cullin Repeats"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.130">
        <property type="entry name" value="Cullin, Chain C, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045093">
        <property type="entry name" value="Cullin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059120">
        <property type="entry name" value="Cullin-like_AB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016157">
        <property type="entry name" value="Cullin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016158">
        <property type="entry name" value="Cullin_homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036317">
        <property type="entry name" value="Cullin_homology_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001373">
        <property type="entry name" value="Cullin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019559">
        <property type="entry name" value="Cullin_neddylation_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11932">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00888">
        <property type="entry name" value="Cullin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26557">
        <property type="entry name" value="Cullin_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10557">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00182">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00884">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75632">
        <property type="entry name" value="Cullin homology domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01256">
        <property type="entry name" value="CULLIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50069">
        <property type="entry name" value="CULLIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Cullin family profile" evidence="4">
        <location>
            <begin position="317"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1748600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="662" mass="75317" checksum="EB06B4ED0773562A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YNM7</accession>
    <name>A0AAD8YNM7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_000743</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YNM7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1748804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="134" mass="14699" checksum="A75CA423E6C8C598" modified="2024-05-29" version="1">MRSEPRSDDDAQNIQGSLDNLASDSGLLKMLIWLLAPVAMELSKYPQLMSSDPCEAQGFVNRLSDQARNNMQYASALLDALPENEEQTNDYLRWALAEADLLLRNNKNIVDALSKALAGGAATVGDCVAILEEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3N1</accession>
    <name>A0AAD9D3N1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016578</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000059">
        <property type="protein sequence ID" value="KAK1732731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="2">
        <location>
            <begin position="396"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1403" mass="157597" checksum="C153D11233596819" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4C2</accession>
    <name>A0AAD9D4C2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016724</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000063">
        <property type="protein sequence ID" value="KAK1732583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4C2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="85" mass="8946" checksum="7EE281005193FA62" modified="2024-05-29" version="1">MTADQDSTFELVPSDHPPIVEAVPTTNDRLHASGNEDENENPSDTDIIVGCGVAGLIVGGPFLALITALGGNWGTKPRMRNSSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D576</accession>
    <name>A0AAD9D576_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Leucine-rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015909</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000050">
        <property type="protein sequence ID" value="KAK1733350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D576"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="311" mass="35279" checksum="A6EC0EA99EF3A40B" modified="2024-05-29" version="1">MMAANGWYIYNGLEAVPPGVTRVRIHESVTVIPARAFEGNCNIEELECHDLVKTVERSAFYNCTSLRKVIMPVVEVVEDCAFGDCKALTVVECDKLERIGGGAFSWCKSLTSINLPSAKIVEYIAFCDCHALAKVKFGDKLERIIRGAFRNCTSLEQITIPLKDGMNIADNTFQRCENLKHVDLVEGAVLRDTVDALLLDEWRNDMTDKLDVINQSLPTTPAGDHFYDEGEKARAIRMWISSVLFKIIHYKAQHRSLLNEVATLQQDFPQDIMLKNILPFLKLPSHSFEGENNEGGGERQSHQRFIRRRFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5F4</accession>
    <name>A0AAD9D5F4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000046">
        <property type="protein sequence ID" value="KAK1733603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5F4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="282"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="435" mass="48659" checksum="1B468D613950B7E9" modified="2024-05-29" version="1">MEYSTVEVEAFATGLLCDNVKDGYVCDSLIKLVDSSHMTIKYRYSPLEVNETMKHRLAKSVSALLQNRDADGKTLLHYITAYNVVQTNNLDEPGKMMLILHSVKEKYIEEGRTFPFNYFSWDSFNGDETLGNEMFILEKNRRRQTQEKVGEIARWILKKEPTLTESVDNEGLNPFHFQYAVSVGKKWSEGLDVVAGLVPGWTQAHGKVGLSPFAIAGYACDDIDTLFELLRFDSSVLSGYDVDGDTAKRDEDSSEVKDDESVKQMINEVLRPLAAIIEANDPVAIRQKGSEYFGQGDYGAAVELFKKAAKLGDGEANYQLAGCYGLGLGVERKPKMEIFYWEEAAIGGHPKARYNIGVTEKRNGRFDRAQRHWIIAASQGHTNSVKALVENHKRGLVKKEVADDALRAYKAAVDATKSPQREAAEAVNQNVNSYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D795</accession>
    <name>A0AAD9D795_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">gamma-glutamylcyclotransferase</fullName>
            <ecNumber evidence="1">4.3.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_013642</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.9" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D795"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003839">
        <property type="term" value="F:gamma-glutamylcyclotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06661">
        <property type="entry name" value="GGCT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.10">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009288">
        <property type="entry name" value="AIG2-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017939">
        <property type="entry name" value="G-Glutamylcylcotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013024">
        <property type="entry name" value="GGCT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036568">
        <property type="entry name" value="GGCT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12935">
        <property type="entry name" value="GAMMA-GLUTAMYLCYCLOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12935:SF0">
        <property type="entry name" value="GAMMA-GLUTAMYLCYCLOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06094">
        <property type="entry name" value="GGACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110857">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma-glutamylcyclotransferase AIG2-like" evidence="5">
        <location>
            <begin position="20"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR617939-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR617939-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1735479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="289" mass="32856" checksum="CF3FFC59F397B6C0" modified="2024-05-29" version="1">MTLEALSSSSASDAGNAYYFAIGAMMNPNSIKNRNIYPIRSFPAELFDFELKFNGTLGFADAIPSKGSSFHGVLHLVDAETMSRLDALEISYKRVDGQARLYDGTMVTATVYTKDSFVSTQKDNPPQQRYLDLLIEGAKHFQLHEKQIKFLESHECVPRPQPHEFKSFGPAAEDAPLMSYENDICPFNGRDTPNLRLAVNGKVLEIFVKNVEGTLFRNSMNFYRQFGQRVELTLSRILYDPKYGCPESLEECTREQSAYIEHILYQGSEVNTSIDHWKDIGCIRQEYKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D822</accession>
    <name>A0AAD9D822_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidylinositol-4-phosphate 5-kinase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011483</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D822"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215:SF14">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="285"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="313" mass="35608" checksum="E935480DD2EDD379" modified="2024-05-29" version="1">MMKHSGEGKIKYDNGNIYKGSFRDAAPHGLGKMSYKDGRVCDGIWKNGEIEYEGELANGMPHGKGKKIYSDGSYEGEWKDGLKYGNGIYKWTDGSLYEGQYKDGKKHGKGKFKWSDGSSYDGEWKVDERYGKGTQKRADGSVEYYGEWKRDLPDGVGIQNFEDGDVYAGEWRADYMNGKGVMTYANQDIYDGEWKRGRKDGQGIMKYHNGDVYEGRFSKGNMHGKGIFEYAGGDILKSIGEWKDGKKCGLFEDIVRKRVYYDNDVKANSIVKRERNTIAKSIVKREKVSDEDTVTDDAPPRKRRRRNVYNGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D831</accession>
    <name>A0AAD9D831_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Tubulin beta chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_011788</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D831"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02187">
        <property type="entry name" value="beta_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000002">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000002">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000006">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013838">
        <property type="entry name" value="Beta-tubulin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002453">
        <property type="entry name" value="Beta_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01163">
        <property type="entry name" value="BETATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00228">
        <property type="entry name" value="TUBULIN_B_AUTOREG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="10">
        <location>
            <begin position="47"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="11">
        <location>
            <begin position="233"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="409"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="417"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1737502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="430" mass="47979" checksum="B9A7BFB0FA8C1695" modified="2024-05-29" version="1">MREIVHMQAGQCGNQIGSKFWEVMSQEHGITPAGNYEGDNDNQLKRINVYFHEGQGGRYVPRAVLTDLEPGTMDAIRASPAGGMFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAIMDVTRKEAEACDMLQGFQITHSMGGGTGRYGNSSCFQGSVVPSPKVSDTVVEPYNATLSIHQLVENADQCFALDNEALYDICFRTLKLANPSYSDLNHLIAAAITGTTCSLRFPGQLNCDLRKLSVNMVPFPRLHFFLVGFAPLTSHKSQDFRVLSVPELTQQAFDAKNMMCACDPRHGRYLTCAMMFRGAMSSKEVDDEMLKMVSKNSGYFVEWIPNNLKASICDVPPSGMKMSSVFIGNSTCIQEAWKRVAEQFTVMFRRKAFLHWYTGEGMDEMEFTEAESNLNDLVSEYQQYQDATTGDDEENDPENWEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8K0</accession>
    <name>A0AAD9D8K0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoglycerate mutase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8K0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47580">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47580:SF1">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1736799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="546" mass="59159" checksum="81C1D95730D9B036" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D979</accession>
    <name>A0AAD9D979_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Ubiquinol oxidase 4</fullName>
            <ecNumber evidence="14">1.10.3.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_010777</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the alternative oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.10.3.11" evidence="14"/>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D979"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009916">
        <property type="term" value="F:alternative oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102721">
        <property type="term" value="F:ubiquinol:oxygen oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010230">
        <property type="term" value="P:alternative respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01053">
        <property type="entry name" value="AOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.140">
        <property type="entry name" value="Alternative oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002680">
        <property type="entry name" value="AOX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038659">
        <property type="entry name" value="AOX_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31803">
        <property type="entry name" value="ALTERNATIVE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31803:SF10">
        <property type="entry name" value="UBIQUINOL OXIDASE 4, CHLOROPLASTIC_CHROMOPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01786">
        <property type="entry name" value="AOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042249851" evidence="13">
        <location>
            <begin position="20"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1738747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="290" mass="33213" checksum="73CA1F9F9190D1F3" modified="2024-05-29" version="1">MNRPLLISCLLASAGSISAFAPPQSSAVNYAIGRRRSTTPLFSAIVPPPEERSDANPSTKFGSPLSDGLKEANRWSIGFLKGTIFDTFFAGEDRAYARFYALETIARVPYFSYLSVLHLYETLGRWRRAKYLKLHFAESWNELHHLLIMEELGGNDRFLDRFLAQHIAFGYYGVVILSYLINPIFAYNLNQDVEEHAFSTYDEYLRENEEMLKGQPAPQAAIDYYIDGDMYMFDEFQTTCEMRRPKIENLYDVFVAIRDDEAAHVETMKALQTELDVASIHDGECEVDIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAF1</accession>
    <name>A0AAD9DAF1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009032</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAF1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="340" mass="38483" checksum="D8F8D2DA18A9591D" modified="2024-05-29" version="1">MDPFSICPNCKQYYQNDVHKALAKACVEFVEFVEKGFKDKKNFLAHCNLYAHALMNQVAMLDGENEGEITGGEEIIAKFFSVMEEVKSQLEQLEQLESLDRGTCLRLCDVFIDVEASGNANIGHFYRSMNSREGQVKAKEHFEKARDLSKTMRLKEAEISVSEMNQIISELESELSGNVVHDEELDVIYLQRDYHKCLERYGGQSSCITIHTGVALSRALITEYRTIEAEILLSKLVDVSLRTHGHDNRASKDAMSGLTLARERKVVVRFEDVSGWFQALRYENEGEDCVVQGPIADPRNVDEDEQRSYESTRIIPFPGTPVICHGLQKAVHLNGKIGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAP6</accession>
    <name>A0AAD9DAP6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptidase S49 family protein</fullName>
            <ecNumber evidence="7">3.4.21.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_010440</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S49 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAP6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07023">
        <property type="entry name" value="S49_Sppa_N_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002142">
        <property type="entry name" value="Peptidase_S49"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047272">
        <property type="entry name" value="S49_SppA_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42987">
        <property type="entry name" value="PEPTIDASE S49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42987:SF4">
        <property type="entry name" value="PROTEASE SOHB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01343">
        <property type="entry name" value="Peptidase_S49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S49" evidence="6">
        <location>
            <begin position="577"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="81"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="434"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="513"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="105"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="446"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="521"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1739124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="817" mass="90711" checksum="C9B7A32484C95663" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAT5</accession>
    <name>A0AAD9DAT5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009772</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAT5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="270" mass="29522" checksum="E8A465907B294302" modified="2024-05-29" version="1">MSRAFTPPDTLSQDDIRTVADVRRAVWINGLFGLGAGSAIGMIGHLALQTLQRRHVPKVASTAEKSTEKTSATTLSKKQTTSSILYKLLKPLPPLTKNTFLLSFLGGGALGSFVLSSTAGKNAVHLLHPIFNVGRDEYAGMSPYQIEAKKAEMTLQQQQSGAVEDGALTAAAAINQDDQLDIQHHKQRTLHRKASIKERLESGHSLSDTHSTEAHYHPSDEEEIVRDKAMHRAEVWERRQTERRRWVKDKIESGGSLSDSHVTGGGGSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DB73</accession>
    <name>A0AAD9DB73_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008353</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DB73"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08161">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042069285" description="SET domain-containing protein" evidence="1">
        <location>
            <begin position="31"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="299"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="643" mass="71469" checksum="F91D6FC80A6C426B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DC62</accession>
    <name>A0AAD9DC62_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DC62"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="573"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="121"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="169"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="210"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="230"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="362"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="672" mass="70602" checksum="2957A38960F02643" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCK9</accession>
    <name>A0AAD9DCK9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008236</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCK9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="141" mass="16129" checksum="34D830486BF285AE" modified="2024-05-29" version="1">MKKTTTTTTLTFILELMYNEDFRGEFPLLSQYAIPLFDMEADDNPARMKKQSTRDGLLREIVQLKQSYGEPLKFESQNSVQKTELMPVGNDGVSGPLDTVFEKLGEEMAIESILKYLTERHQAKLLAELTKLKLIPKLLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFH0</accession>
    <name>A0AAD9DFH0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heat shock protein 70 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_004548</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000029">
        <property type="entry name" value="Heat shock protein 110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639:SF4">
        <property type="entry name" value="HSC70CB, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639">
        <property type="entry name" value="HSC70CB, ISOFORM G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="939"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1004"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1056"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel" evidence="5">
        <location>
            <begin position="1014"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="407"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="660"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="731"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1105"/>
            <end position="1147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="432"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="673"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="731"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="781"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="818"/>
            <end position="856"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1745257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1392" mass="153720" checksum="573FC499D217B913" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFR5</accession>
    <name>A0AAD9DFR5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFR5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1743938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="140" mass="16130" checksum="D95FFB139BF81C6D" modified="2024-05-29" version="1">MLTVGRAFINGLDEPGKIHVILSALKEEYERREWAFPFTFADRWWRDSRQRNDHLAKTTPKQTQEKIGEIAAWKLKEDPTLADYVDSDGLNPFQYAVSVGKKWIDDLDVGTKLGPGWTHVGVRLQSQDTPMMIWIHCLSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGA3</accession>
    <name>A0AAD9DGA3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA repair protein RAD51 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_003258</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the RecA family. RAD51 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGA3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000794">
        <property type="term" value="C:condensed nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070192">
        <property type="term" value="P:chromosome organization involved in meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000730">
        <property type="term" value="P:DNA recombinase assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042148">
        <property type="term" value="P:DNA strand invasion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990426">
        <property type="term" value="P:mitotic recombination-dependent replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19513">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000092">
        <property type="entry name" value="DNA repair protein Rad51 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011941">
        <property type="entry name" value="DNA_recomb/repair_Rad51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016467">
        <property type="entry name" value="DNA_recomb/repair_RecA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010995">
        <property type="entry name" value="DNA_repair_Rad51/TF_NusA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003301">
        <property type="entry name" value="PRK04301.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02239">
        <property type="entry name" value="recomb_RAD51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942:SF39">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942">
        <property type="entry name" value="RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005856">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47794">
        <property type="entry name" value="Rad51 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecA family profile 1" evidence="8">
        <location>
            <begin position="104"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="RecA family profile 2" evidence="9">
        <location>
            <begin position="281"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1746651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="344" mass="37491" checksum="52C9E35B712BB9C3" modified="2024-05-29" version="1">MAAVAQQYYEEAAQNEQMGEEDGTYIAYQPLDGLQEHGVAVNDIQKLNDAGFHTVESVAHATVRKLSEVRGLSEAKVLKIKEIVKGMVVMEFKTAADALEDRKSLVTLTTGSTELDKLLEGGIETGSITEVFGEFRTGKTQLCHTLCVTCQMPVTDGGAEGKAIYIDTEGTFRPQRLQAIAERFGMDPSVALENVAYARAHNSEHQTELLKMAAAIMSQDRYALIVVDSATALYRTDYSGRGELSERQMQLAQFLRQLTRLAEEYGVAVFITNQVVANPDGMSFAKDSTKPIGGNIIAHASTTRLRLRKGRGENRICTVFDSPTLPEADASFAVGPQGICDAQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGG1</accession>
    <name>A0AAD9DGG1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002899</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGG1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="189" mass="21428" checksum="5D96EB7159FAA758" modified="2024-05-29" version="1">MSDDLWETIDWGDDADDSTHPSQATVMSPTFFHRKETTATARLSGSSAGSESDKPSDPSTTVICPERKQHARNKRSSWFDADLTKLVPLEDEQGGYRTSGRPQLKGSNTRVENETRRRLRRRQSDYAIEKRRASEKHASLDERRPVSRSLTKRLLSSVGLRRDSEAASVSDDEELDVPFPTNTRRQSCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGI5</accession>
    <name>A0AAD9DGI5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGI5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="183" mass="21033" checksum="B3CB699F207F5241" modified="2024-05-29" version="1">MESTGKRTRRQPNRYADEAAKITERSMKTKQKKAAASSKKTASTTTSATNASRGKLLKKELAKYNLTRRKDSKLCDAFVKGTTNKSVEEVADVMCRMKYLYGGYCKEFNKEIREVEDEIDREVDDIAEQYKGYNSDPFSEFEGYYRGIRGDACSEVTGYYSFADYKLDVANAWTAFPEQWPWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGK6</accession>
    <name>A0AAD9DGK6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGK6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="257" mass="27709" checksum="05EB9EE6E886A12F" modified="2024-05-29" version="1">MVCGTFYRTALGIIGTYKSAACNEHECEAQPQPQPHNKPWIAAPSISGNTVIIIPSSSIGPRSLGAPSFQSSSAPSQSAAPPSLPSSLDRGKSMTKKNNDATTAPIPLPNHHIHRTHSEVQLAQDQLVADYQDGKMYERILIGIMRRCDELGSCHPKTSSSLENIVNTKMQDFRSLSERGTTDAKEDWVVGDDDEPSYSIGEERTASFISTSLTSSENIGSGRRNSSLSSLSCLTSHMDGTADATHDIESGIFELEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGR2</accession>
    <name>A0AAD9DGR2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004324</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGR2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="153"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="276" mass="31765" checksum="8A9D7F1AA985B540" modified="2024-05-29" version="1">MEQSNMERNVVQTEMGGKVLTEEKKRRKRRDKLLDSIPSEVLDSEAFDQMSQNEVMEAIITYMNANERRLESRKRKKVEKRKHREVTREWKRSVKEQALTSLDAKDARAQVFRTETQSSSSPLSFTPSVKIMQKLRAKRSEQSKKAFKTRLMNSNSSQTSSSNEMTRLRRRYKKDFDDDSDDISPVQAILRIDMALDHKKLPSSSDVEIMLKPGRLGRRRAVLKRILNDCFDLRGKCVPPSDGIDNGGSLLFVTKCTIDELGSFVLAKMSERVSNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHL4</accession>
    <name>A0AAD9DHL4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHL4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39290">
        <property type="entry name" value="C3H1-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39290:SF6">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="636" mass="70176" checksum="A74EEE5F9B17D3D2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHM8</accession>
    <name>A0AAD9DHM8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Casein kinase I</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_003842</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHM8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14125">
        <property type="entry name" value="STKc_CK1_delta_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000159">
        <property type="entry name" value="Casein kinase I hhp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000538">
        <property type="entry name" value="Putative Casein kinase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050235">
        <property type="entry name" value="CK1_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11909">
        <property type="entry name" value="CASEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="9"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="303"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="330"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1745918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="396" mass="44946" checksum="88DC1E3F20D8392F" modified="2024-05-29" version="1">MELRVGKKYRLGRKIGSGSFGDIYLGTNMTTGEEVAIKLESVKTKHPQLLYESKIYRILHGGLGIPNVRWYGIEGDYNVMVLDLLGPSLEDLFNYCGRRFQLKTVLMLADQLLGRLEYVHTKSFIHRDVKPDNFLIGLGKRQSVIHIIDFGLAKKYRDPRSHQHIPYRENKNLTGTARYASINTHIGIEQSRRDDLESLGYVLMYFIRGSLPWQGLKANTKKQKYERIMDRKMSTSTEQLCKGYATEFRSYFEYCRSLRFEDRPDYAYLKRLFKELFYRKGFQYDNMFDWTVLNLQQERAKLPPERPLLGGGKGGDADAAAQGGNGQSSGERKQPPENERERSRSANDGIPNNGTSQRSGSRGGRQQGGVAVAAEPSESQNFAAAAAAEDDLKVGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DI46</accession>
    <name>A0AAD9DI46_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA2/NAM7 helicase helicase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002283</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DI46"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="1">
        <location>
            <begin position="30"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="195" mass="21921" checksum="283BA6568D92C42E" modified="2024-05-29" version="1">MNHYFGEVKKLAESFDAVVGKRATLSLSGAAKKRPRILVCAPSNAAVDNVIMKIMEDGFVDGNGCRYNPSIVRVGVGQSASVRDVCLGEKVDNYMTEAMDVTKLDNTIEGYKSECRRIHSDIVKLRERMTAMKKATPYPLAKEWEVRIDENVCRVFYVNHKTNKIDSSIFKDKRTTFECPPPPEEDNAISRHCNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIJ4</accession>
    <name>A0AAD9DIJ4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA topoisomerase 2</fullName>
            <ecNumber evidence="12">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">QTG54_001095</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="12">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Plastid</location>
            <location evidence="3">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the type II topoisomerase GyrB family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the type II topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="12"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIJ4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00822">
        <property type="entry name" value="TopoII_Trans_DNA_gyrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.670:FF:000002">
        <property type="entry name" value="DNA gyrase subunit B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.670">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002288">
        <property type="entry name" value="DNA_gyrase_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001241">
        <property type="entry name" value="Topo_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000565">
        <property type="entry name" value="Topo_IIA_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013759">
        <property type="entry name" value="Topo_IIA_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013506">
        <property type="entry name" value="Topo_IIA_bsu_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018522">
        <property type="entry name" value="TopoIIA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45866:SF1">
        <property type="entry name" value="DNA GYRASE SUBUNIT B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45866">
        <property type="entry name" value="DNA GYRASE/TOPOISOMERASE SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00204">
        <property type="entry name" value="DNA_gyraseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00986">
        <property type="entry name" value="DNA_gyraseB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01159">
        <property type="entry name" value="DNAGYRASEB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00418">
        <property type="entry name" value="TPI2FAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00433">
        <property type="entry name" value="TOP2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="Type II DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00177">
        <property type="entry name" value="TOPOISOMERASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11 12 16" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <keyword evidence="9 12" id="KW-0799">Topoisomerase</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041981284" description="DNA topoisomerase 2" evidence="14">
        <location>
            <begin position="30"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="domain" description="Toprim" evidence="15">
        <location>
            <begin position="641"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="270"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="289"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1749156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="876" mass="94525" checksum="6B27D2D270558EE5" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJ78</accession>
    <name>A0AAD9DJ78_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">5'-AMP-activated protein kinase subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_001668</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-AMP-activated protein kinase beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJ78"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031588">
        <property type="term" value="C:nucleotide-activated protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02859">
        <property type="entry name" value="E_set_AMPKbeta_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:003294">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.250.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032640">
        <property type="entry name" value="AMPK1_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006828">
        <property type="entry name" value="ASC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037256">
        <property type="entry name" value="ASC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050827">
        <property type="entry name" value="CRP1_MDG1_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10343">
        <property type="entry name" value="5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10343:SF84">
        <property type="entry name" value="5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16561">
        <property type="entry name" value="AMPK1_CBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04739">
        <property type="entry name" value="AMPKBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01010">
        <property type="entry name" value="AMPKBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160219">
        <property type="entry name" value="AMPKBI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Association with the SNF1 complex (ASC)" evidence="3">
        <location>
            <begin position="234"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="213"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1747705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="321" mass="34718" checksum="F9F27C8E383B934E" modified="2024-05-29" version="1">MGNQPSGTGSMSGSRHQSGQGSSYGGQQQQASKPPGGAAPVGYMSAHAQQYGVSNDGGGGGRPVKRSASDTSMTDMMAMGPGGNTGGANIPLDLASISAAEEDTVPTVFRWEHGGRNVYITGTFNGWSRQIPMHRSGNDFTYIHNLKRGKHAFKFIVDDEWRFAPDQPTVADIEGRINNFIDVTDFKAYTGDKEFENERHADHCAVFHAQQTYAGDDSTGGDSTGDKKGSQGRADPDGEIYGHAMPDLDEYTKEPPPLPPHLRHIILNKPPQLQDTAALPVPQHVALNHLYCTAIKDNMMVLGITQRYKTKSCTTVYYSPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XR89</accession>
    <name>A0AAD8XR89_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Cytochrome c oxidase subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_017091</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="mitochondrion" evidence="11"/>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome c oxidase subunit 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000083">
        <property type="protein sequence ID" value="KAK1732050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XR89"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031967">
        <property type="term" value="C:organelle envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031090">
        <property type="term" value="C:organelle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01665">
        <property type="entry name" value="Cyt_c_Oxidase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.70:FF:000082">
        <property type="entry name" value="Cytochrome c oxidase subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.80:FF:000002">
        <property type="entry name" value="Cytochrome c oxidase subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.80">
        <property type="entry name" value="Cytochrome c oxidase, subunit III, four-helix bundle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024791">
        <property type="entry name" value="Cyt_c/ubiquinol_Oxase_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033945">
        <property type="entry name" value="Cyt_c_oxase_su3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000298">
        <property type="entry name" value="Cyt_c_oxidase-like_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035973">
        <property type="entry name" value="Cyt_c_oxidase_su3-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013833">
        <property type="entry name" value="Cyt_c_oxidase_su3_a-hlx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11403:SF7">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11403">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00510">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81452">
        <property type="entry name" value="Cytochrome c oxidase subunit III-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50253">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="170"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="207"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Heme-copper oxidase subunit III family profile" evidence="10">
        <location>
            <begin position="12"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1732050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="273" mass="31443" checksum="9D393E460BEF2C5D" modified="2024-05-29" version="1">MKNKIRFKYLKTKHSWHLVDPSPWPLLASLGAFFMTSGTVLYMNKFLGGGQLALIGFFVLLYVMYTWWRDIIREATFEEQHTVSVQRGLRLGMILFIVSEVMFFFAFFWAFFHSSLSPTYNLGGVWPPEAIQTIQTSGIPLTNTFFLLSSGATVTWAHHAIIVRAKKQAIVGLLFTIFLATIFTLLQGMEYVEAPFNINDSVFGSCFYMATGFHGFHVFVGTCCLIVSLLRIVYNHFTSTHHFGFESAAWYWHFVDVVWLFLFITVYWWGGIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRB5</accession>
    <name>A0AAD8XRB5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Small ribosomal subunit protein uS3c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rps3</name>
        <name evidence="12" type="ORF">QTG54_017140</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="12"/>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7 10">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 10">Plastid</location>
            <location evidence="7 10">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 9">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRB5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02412">
        <property type="entry name" value="KH-II_30S_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.20:FF:000001">
        <property type="entry name" value="30S ribosomal protein S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="entry name" value="Ribosomal protein S3, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01309_B">
        <property type="entry name" value="Ribosomal_uS3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057258">
        <property type="entry name" value="Ribosomal_uS3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005704">
        <property type="entry name" value="Ribosomal_uS3_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_uS3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018280">
        <property type="entry name" value="Ribosomal_uS3_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01009">
        <property type="entry name" value="rpsC_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11760">
        <property type="entry name" value="30S/40S RIBOSOMAL PROTEIN S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11760:SF19">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="Prokaryotic type KH domain (KH-domain type II)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="Ribosomal protein S3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00548">
        <property type="entry name" value="RIBOSOMAL_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="10 12" id="KW-0934">Plastid</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KH type-2" evidence="11">
        <location>
            <begin position="39"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1732097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="217" mass="24379" checksum="AAF459BD7393E534" modified="2024-05-29" version="1">MGQKTHPLGFRLGITQEHRAAWYADFKQYSNLLEEDDKIRTYLNKLAKLASISNIHINRNGLGDQIELNIETGRPGVLVGDNGSKIKTLAANIKKFIPNDRQITINVIEVENANSNASLIADLVVQQLEDRVAFRRAIREGLKCSQDNAVNGIKIQVSGRLNGAEMARSEWIREGRVPLQTLRADIDYATKEANTIYGVLGVKVWLFKNEIIKNIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRZ0</accession>
    <name>A0AAD8XRZ0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Plastid lipid-associated protein/fibrillin conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_016588</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000059">
        <property type="protein sequence ID" value="KAK1732741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRZ0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039633">
        <property type="entry name" value="PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006843">
        <property type="entry name" value="PAP/fibrillin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31906">
        <property type="entry name" value="PLASTID-LIPID-ASSOCIATED PROTEIN 4, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04755">
        <property type="entry name" value="PAP_fibrillin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0934">Plastid</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastid lipid-associated protein/fibrillin conserved" evidence="3">
        <location>
            <begin position="81"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1732741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="299" mass="32278" checksum="5764EFEFF1A32E1E" modified="2024-05-29" version="1">MNTSTMARFAGSAAAPSAYLLTLSIIIIVAALSISPSAAFTSSSSSCRRCVVKTNARASSISVATAALPKLDQDTTSAIENAKQQINQAISTTDKGRSSNLSSTQRSQIASQLAHLESLCPLSEPARNPLMEGPWIVLYTDAPPPSNGQLGPFKGVAKQVIDLQKGTYKNELYVGGSGTDEDENAWLGAVLEATWKEWDGVYLDNDQDASVTTLATTTSSDSSNSNNNIDHGATTWRVDFLSLTLSIFQLPIFTQKFKEGTARTWKMTYLDGDTRIVRAGKTGRGEDDWIFYMRRGVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XS83</accession>
    <name>A0AAD8XS83_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SET domain-containing protein</fullName>
            <ecNumber evidence="4">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_016417</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XS83"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF137">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042072736" evidence="2">
        <location>
            <begin position="23"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="3">
        <location>
            <begin position="116"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1732879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="443" mass="48254" checksum="4EC654D6C92F070E" modified="2024-05-29" version="1">MMNKNMNSIAVLLMALCPSANAFVSPSATSCSLPSSFRMPSTSTQALFMAKSKTKKKKPAASSGGLKGFGGSSKSSTKATAAAGSIDRSKAALKFYNYLERNGAEANLKRVGLGYFPLQIGPSEKDVIQLRGVIALRDIPKGEPIIEIPYEMAIDLGRESSDPTLPATSFLQKYCVWKCDSDGPPSDKERGDYFAMLPEYLSSDCLGSTDFFSDEALEMLQSPLIKEETLSRKDLVHLRYERDVETMAEMSSNLYRWSGEEVATESHLQWASWIITSRVLTVQGPPESGIANRLLIPLIDMCNHDRDSPHILTGRAMTGATLKVVAGVDVKAGDAINISYGGSVEGNDRFIQDYGFLDGGGSKERGKSEVAEAYKIVARKLTGRNRALTKLTVDDQERALEALKATTLEEDEEMLNSGKITNNDERAAIEFRIGMKKALAGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XS93</accession>
    <name>A0AAD8XS93_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycosyl transferase CAP10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_016432</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XS93"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF35">
        <property type="entry name" value="PROTEIN O-GLUCOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
        <property type="entry name" value="Glyco_transf_90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00672">
        <property type="entry name" value="CAP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="3">
        <location>
            <begin position="299"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1732894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="583" mass="67353" checksum="25516E3EF81DF061" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSG5</accession>
    <name>A0AAD8XSG5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_016557</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000058">
        <property type="protein sequence ID" value="KAK1732754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSG5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042014008" evidence="3">
        <location>
            <begin position="26"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1732754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="397" mass="42126" checksum="E52C7C560083DAB4" modified="2024-05-29" version="1">MYIMVPLSVTSTVAILLTFNQSVIASSGLNLRRASSANVGARSLRGDVDLTQCYQDIVSVADEQNILTKDAYLLLADIMSNQWFSDNGIDSYTELPYDMKFAFVTLACECRNMGGAENCCQNHRASLNVDGADGQDVSQAQTDYLNDICSLTYSTIGSDRINPKPGEMPTTAQPTPPAPTQPPAPTPSPTKKVDPIITPPTPPPRPDYPSGGMGAGGIAGVSLAAAAVLTLIVFLIGGRKEEEQNEEEKLEDIEADDMLKVDANADVGDDAPDSDGSPDGTKSMTTVFSEQSTIATGVNVAAVAVANTNMLPGIEDSENETDDEENIDQPHEIPGDLSSLSSCSQGDFYANNESYESPALPPAKQDDDINDALDYAIENGNWEQVAASAAALVEKEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSI0</accession>
    <name>A0AAD8XSI0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000055">
        <property type="protein sequence ID" value="KAK1733029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSI0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="717" mass="78068" checksum="90E4BB48BCB94935" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSJ2</accession>
    <name>A0AAD8XSJ2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Trypsin-like serine protease</fullName>
            <ecNumber evidence="7">3.4.21.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_016686</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000062">
        <property type="protein sequence ID" value="KAK1732625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSJ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000002">
        <property type="entry name" value="Transmembrane protease serine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF91">
        <property type="entry name" value="AT26814P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041943107" evidence="5">
        <location>
            <begin position="18"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="6">
        <location>
            <begin position="58"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="412"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="425"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="438"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1732625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="452" mass="48321" checksum="254A7B3CDD6E0A57" modified="2024-05-29" version="1">MMLLFIFLLSSIAASSADDIVGVNMKPENPNKNGVIMPVGLSISTASVADGHAPPQQIVGGTETGGPVGFMVGLRKNAKGAASDTNAPFCGGSLIAPRIVLTAANCMSNFDLYEVIVNMYDVTNKTGVESIALNRGVLGEDIIIHPDYDEDTLENDVALMILPHEVTGITYAKLNEDARQVGDVLRVIGWGRTSLGGEKSDILLEAEVDFVTNKQCNEPYEGFVTDGMLCAARDGTGPCQGDSGGPMMLASDEGDPIQVGITSWGYGGYECANPNYPGVYTRVSYYADWIKKTACAFTGEFCPTCGVSQSLMKVIVHTDNYPVETSWKVTNKCGSSSDPIMWGGDYPKDSKYTTEVTLDCVSEGEYEFTIEDSYGDGTCCGFGYGYYSFQYGDEEAIGGEFGYFETKSLGSCTTSSPTEAPTPQPTQVSPTPLPTQVHLPTNAPTPSQNLRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTA7</accession>
    <name>A0AAD8XTA7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">START domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016346</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000055">
        <property type="protein sequence ID" value="KAK1733015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTA7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34060">
        <property type="entry name" value="POLYKETIDE CYCLASE / DEHYDRASE AND LIPID TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34060:SF1">
        <property type="entry name" value="POLYKETIDE CYCLASE _ DEHYDRASE AND LIPID TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="121"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="233" mass="25685" checksum="98B7783239329E65" modified="2024-05-29" version="1">MSSFTSSSTAAVDEGTSKQCVIDFKCVDSQFFSEFDGSWIVEEYKDDDGVSPPSDGAPITMVRYVVDVRPKGPVPVAALEWRIKEDVPVNILAVSKAATAAMARQQTEQQQQQSVVANVVPQVPLSTQTPSTPLSSPRRRRSPRQATLQPLQRLTNQAANNFKRTAKSVLPSPLYSSAKQIFNNLPRPRRNDAPTMSLQTGSDTFKTETTLASSASKDMDVDWYDDETMAMYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTU2</accession>
    <name>A0AAD8XTU2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_015650</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000046">
        <property type="protein sequence ID" value="KAK1733607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTU2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="7">
        <location>
            <begin position="12"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1733607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="299" mass="33587" checksum="1C6A74E335A7146A" modified="2024-05-29" version="1">MNEDYNMGKTVCASCGSAEVDGIKLKECNACKSVRYCSDACQKNHHKSQHKEACKKRAAELHDEILFKQPESRHDGDCPICCLPMPLDKQKSFMMACCSKTICKGCFHANQKREAKASLNSSCSFCRQPVPKKDELGKQRMKRIEANDPVVLCEEGIELYNKGDHQSALEYYTRATGLGNVEAHYQLAYMNRDGHGVEKDWRKYLRHLVVAAIGGHPTARYNLGCIEWHNGNNERAAKHFIIAAKLGDDDSIKSLMDAYRGGFVSKDDLATTLRAHQAADDATKSPQREAAEEYYQNKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUX5</accession>
    <name>A0AAD8XUX5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cyclin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015317</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1734059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUX5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000093">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="2">
        <location>
            <begin position="39"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="345" mass="39046" checksum="B4B07825E3EFEF6F" modified="2024-05-29" version="1">MKMTMKPTENLSRDTEAVADSLSAMMKREFTSYSCYDGYLNPSDPTMVTADDRKKLVDWCYGVVDHCQLSRETVASAMEMVDRFLSMPSNSADAARVCNEALRDQSKFQLLTIAALYSSIKVNERVALSSELFSEICLRSYTAEEIEAMERTLLNGLSWRCNAPTAHQVGLSILSLILPYVDIPEVTWGFLMDETKYLTELAVQDYYFSTQRMSTTALAAVFNVVNDTSTKVRRQTIGAFLRVIMECFDFDDSEQINAARRRLNFLAKPDTQEDEMMDDEISLESLEESVETIKASNSSSSHPKRGHEGHFWHEKDELGHEQVVSPSSSLRDISSEKQDSSLHFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV09</accession>
    <name>A0AAD8XV09_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_014886</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV09"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32083">
        <property type="entry name" value="CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32083:SF48">
        <property type="entry name" value="TRANS-GOLGI NETWORK-LOCALIZED SYP41-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="184"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="351"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="27"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1734379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="645" mass="72481" checksum="87FA1C1B7C8E1D1D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVB0</accession>
    <name>A0AAD8XVB0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NAD(P)/FAD-dependent oxidoreductase</fullName>
            <ecNumber evidence="6">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_014774</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000038">
        <property type="protein sequence ID" value="KAK1734526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVB0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF309">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="4">
        <location>
            <begin position="7"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="798"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="389"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="394"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1734526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="888" mass="97102" checksum="ABDD1C00D57DA1EE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWG1</accession>
    <name>A0AAD8XWG1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014378</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWG1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="172" mass="19399" checksum="2CDCA5C51D16B36B" modified="2024-05-29" version="1">MTAVTKTSLTTASSSTTSSGSSNVGSRHNDSYPDEILARNTIITFEKKSNKDVKCPSIPFFDYLEEQVSKLIEKNESAPKCYVATILPRRNSITHHPELSPISSQSVAVAEAKNIRRLRREVLGLYRTLDTLKKDSREWMLLKSKLDAAREELDAVLEDQQLVRSIETVKTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWI6</accession>
    <name>A0AAD8XWI6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014423</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWI6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="37" mass="4281" checksum="5884D800447C1A97" modified="2024-05-29" version="1">MTPAEHKERGVLYVTQALNMSRNMEPFSNVKGSSWRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWV1</accession>
    <name>A0AAD8XWV1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWV1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010736">
        <property type="entry name" value="SHIPPO-rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40429">
        <property type="entry name" value="FLAGELLAR ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40429:SF1">
        <property type="entry name" value="FLAGELLAR ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07004">
        <property type="entry name" value="SHIPPO-rpt"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="311" mass="33624" checksum="EEEE3749639EE3F9" modified="2024-05-29" version="1">MDLGLSHNQREASFKDGCLSLRQAALEKQSSRLTPGPVYNPNVSCSSTTKNKLRNITFGSGPARFDSVPDVKNRPSTPGPHEYCPKKILAAKGSPSRPISFGSATRACNADNPSSKLSPGPSEYDPESIRRGWSFTRRGSSNVKFGTAKSLSDKKSCSQPGVGPQTYDPDAIRRGIMFTRRSNIQSVTFGRPSSARPSSRQSSGRPSSARPSSARPSSRRGSKSSTVSFCDEQPGPQQYDTEAIRQGVYSLSTKRRPSGIVFTTGPRTYNDAEERERASKPGPCTYQAPSSLGKQANSRHKNQPALSFGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XX46</accession>
    <name>A0AAD8XX46_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF2997 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013697</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XX46"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021375">
        <property type="entry name" value="DUF2997"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11211">
        <property type="entry name" value="DUF2997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042218116" description="DUF2997 domain-containing protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="124" mass="13562" checksum="AD52B1DFD43DA1F1" modified="2024-05-29" version="1">MFRITASIMLAAYAAFVAPPATNAFVTPNLQSSRCSSNTNKSQLYSDSGSMEEIEFRIYPDGRVTEVVRGVKGENCEKITEAINNQLGNVVASQPTEEMYEQEVVIESTIQEKADGGWDGASSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYU3</accession>
    <name>A0AAD8XYU3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF3067 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYU3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.40">
        <property type="entry name" value="Protein of unknown function DUF3067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021420">
        <property type="entry name" value="DUF3067"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35126:SF1">
        <property type="entry name" value="DUF3067 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35126">
        <property type="entry name" value="SLR0598 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11267">
        <property type="entry name" value="DUF3067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042163687" evidence="2">
        <location>
            <begin position="20"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="223" mass="25785" checksum="3BCEA380BA498AE9" modified="2024-05-29" version="1">MILCKMKIIYATIFLPAAAAFVATSTPRRIPATFLQSSPFDEFLGNIFGKDEDKDKSRNKDSDIINDEEINISSFQQELTKRQQQQPHQELETDIDNAITDANKEEEEEEEFDGYMMRDAIYNKFGECFDVDFNKVDSYGFRSVYLNIMPFRLGGKRFRHETELDYLCHLQAVVEILQKYDQLDYVLAQLDETTKKPRAGTSPLIAVPLRLDLTEEQVNQIMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZ58</accession>
    <name>A0AAD8XZ58_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_013176</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZ58"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1230.10">
        <property type="entry name" value="MTH938-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036748">
        <property type="entry name" value="MTH938-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007523">
        <property type="entry name" value="NDUFAF3/AAMDC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21192:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21192">
        <property type="entry name" value="NUCLEAR PROTEIN E3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04430">
        <property type="entry name" value="DUF498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64076">
        <property type="entry name" value="MTH938-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1736040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="161" mass="17852" checksum="F41E43EA197B86C0" modified="2024-05-29" version="1">MSSEITRGTDLLADSLAHGPRRKIVLESYAPSGVDVKGFIQVGEQPDDDDNAPGEDKVVHMNGSIVAFPDACFLMNIHTPEEVTLECLSVVKLYQPTVEYLFIGCEHPVPPSEMNKIKAEFRKKDVVVEQMDIMNCIGTFNILNGEDRRVACVLVVDETEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZV4</accession>
    <name>A0AAD8XZV4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Multidrug and toxic compound extrusion (MATE) family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_012419</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZV4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13136">
        <property type="entry name" value="MATE_DinF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044644">
        <property type="entry name" value="DinF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42893:SF46">
        <property type="entry name" value="PROTEIN DETOXIFICATION 44, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42893">
        <property type="entry name" value="PROTEIN DETOXIFICATION 44, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="470"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1736974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="612" mass="64448" checksum="D25B6C42647D0C23" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y011</accession>
    <name>A0AAD8Y011_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Large ribosomal subunit protein uL3m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_013026</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Plastid</location>
            <location evidence="3">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y011"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000004">
        <property type="entry name" value="50S ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01325_B">
        <property type="entry name" value="Ribosomal_uL3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_uL3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019927">
        <property type="entry name" value="Ribosomal_uL3_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_uL3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03625">
        <property type="entry name" value="L3_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229:SF8">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL3M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 10 12" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="274"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00035209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1736426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="407" mass="45229" checksum="B3A23843B2B03282" modified="2024-05-29" version="1">MAFRRILTASSRTPLSSVRRVSSHPTQSSLCRSLSSLMERSLSITQTPAVSPLNNNSCTRLYSTTPPTHKVFSLNSDLSDKEIQAIIDKELNLMEEEKLEKEYRNWKPGQRKRPLVMSRRLEDFEEEASGATKWTLRDKRCGALGIKLGMMPVWDEWGERHPCTVLYLDNNVVIRNKSSDSIDAYDSVQIGAGERKAKNVNKPLMCNYAKYGVNEKPPYVVREFRVTTSEAMPPPGTQIHARHFVPGQNVDIAGTSKGKGFQGGMKRHGFKGMPATHGTSKSHRAIGSTGMCQDPGKVFKGKKMPGRMGGVRVTKQNLRIVKIDRGRNLIYVKGAVPGNKGEFVEIRDAVKKPLFGTEKCEGGEASAFPPLPTFEYEDGIDGCGEAGHEIMMPMQEQDPLEIVEEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0Q1</accession>
    <name>A0AAD8Y0Q1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Guanine nucleotide exchange factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011755</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00171">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032691">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HUS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF388">
        <property type="entry name" value="GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12783">
        <property type="entry name" value="Sec7-like_HUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEC7" evidence="2">
        <location>
            <begin position="897"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="826"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1029"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="512"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="826"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1047"/>
            <end position="1057"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1898" mass="209239" checksum="6D3E7ED99EC28E02" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1M7</accession>
    <name>A0AAD8Y1M7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Sodium/potassium-transporting ATPase subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_011824</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1M7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005391">
        <property type="term" value="F:P-type sodium:potassium-exchanging transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006883">
        <property type="term" value="P:intracellular sodium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000083">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000095">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050510">
        <property type="entry name" value="Cation_transp_ATPase_P-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294:SF21">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294">
        <property type="entry name" value="SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08282">
        <property type="entry name" value="Hydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00121">
        <property type="entry name" value="NAKATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="431"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="484"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="861"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="893"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="922"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase C-terminal" evidence="12">
        <location>
            <begin position="440"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase C-terminal" evidence="12">
        <location>
            <begin position="850"/>
            <end position="947"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1737538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="977" mass="108438" checksum="C766D0A6C8158335" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1P9</accession>
    <name>A0AAD8Y1P9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012077</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1P9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="135" mass="15299" checksum="AD7596285A8EBEAF" modified="2024-05-29" version="1">MTGEINGKHFDNREQSDTYKMTRIDVFYGRTDNTPGYKEYTCVVVKTAESGNLRYYDDLYEPAQGCNYQILYEVPMSNLPSLCAKAGVDRPNSTQWVRSPLKDLILQEWRSQATSGGGGQHSISNPMFVGFRHGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1X2</accession>
    <name>A0AAD8Y1X2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Coenzyme Q-binding protein COQ10 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_011393</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with coenzyme Q.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the COQ10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1X2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048039">
        <property type="term" value="F:ubiquinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045333">
        <property type="term" value="P:cellular respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07813">
        <property type="entry name" value="COQ10p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044996">
        <property type="entry name" value="COQ10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005031">
        <property type="entry name" value="COQ10_START"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12901:SF10">
        <property type="entry name" value="COENZYME Q-BINDING PROTEIN COQ10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12901">
        <property type="entry name" value="SPERM PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03364">
        <property type="entry name" value="Polyketide_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Coenzyme Q-binding protein COQ10 START" evidence="4">
        <location>
            <begin position="64"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1738099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="231" mass="26178" checksum="28532F97698638B0" modified="2024-05-29" version="1">MMIEAIRSASSSIMRMRYCCKSSTTKQHCNSSIFRHQNRSIGAARYRSATTHSHVHQSVLTNIHPQHLYNIVNNVDNYKDFLPYCHESKILQTASCGTMMDAVLRIGLPGLSLSLGSNSLLEERYVSRVRMIPASETTPLWTIEAKSIQSNLFDSLKSRWQLSLIDDYANVNGQQQQTGPFCNVNFEVEIQLSNPLISFTLDRVLKDVAKAQVEAFEKRCRAVPFDNESKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1Z5</accession>
    <name>A0AAD8Y1Z5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_011221</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1Z5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="265"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1737927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="370" mass="41834" checksum="B6B31A2C18498FA8" modified="2024-05-29" version="1">MTAKKRARNKTKKAAAATAAATVAAAQPAVEPGRPNAATAPRSQSKSEPQHDLESQIQRQADDSLPRKDDIKEDVDICVHGLDLQYSNERLKETISVCDDVVSKDIAVIHEVFSGKMPQLESIFGGRESLQNVIDEKLNDLFNGDKAANVDAGIVCTLLAKHPEVCDNPIHFKWVISHFLSEGTQCLLQGDTQAARGNAYFASCFSQIMDLMIKGKMMNIPKMMRLYSADEHTLCSFYRNRIPCSCLRKRYKEVKSVEKTDMCWNIACSKPDRFKVDSRSMMCCSRCRQAYYCCSECQEIDWPRHKNLCGWAKDVREVFGAKHIIELKKNEVWNRTFAPLFSKEIQHLKKIGINENDNPLTVRPPIAEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y289</accession>
    <name>A0AAD8Y289_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mitochondrial-processing peptidase</fullName>
            <ecNumber evidence="9">3.4.24.64</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_011625</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.64" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y289"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050361">
        <property type="entry name" value="MPP/UQCRC_Complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851:SF149">
        <property type="entry name" value="GH01077P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851">
        <property type="entry name" value="METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="8">
        <location>
            <begin position="182"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1737853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="436" mass="45074" checksum="C2FDFA6274540F93" modified="2024-05-29" version="1">MTMLLVRPVVRTSARRMSTVAASTVSSDVQSYISEAPAATVSTLGNGVTVASLYNADGSGSGYTTVRLSGVGSRFDTVGGEAAILASSMGGVVGREHISLSSISSLSADAATSNLDALKGNLSCKLAGLSYESQMMDHLHSTAYQNGPTGNSLGNALEGSAESVASVSADDVASLLGGVNGTNVVVVGTGNGSHEKLVAEAEKAYGSLSGASGSKAVGSVADKSAFIGSDVRIRYDSHNTATIALGFEGASWTDPKAMPLALMSTLLGSFSKSDGLGKNVAAAMCQEVADHELASSISVFNLSYSDTGLFGMVATAPDNKLDDLLWYVMPNFVRLAHGVSDEEFTRAKVTLKTQILASFDGDVAAGEQMAQQIGTVGRVVSLTEMMAKVDALTMDDVKAAAGDVINDQDHALAAIGGIHELPDYNWIRRHSYMLRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2G5</accession>
    <name>A0AAD8Y2G5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011252</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2G5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="104" mass="11337" checksum="905B67D7F76EC65A" modified="2024-05-29" version="1">MNLKLLSTSAALALSSIVKTGGAESKAVLADKIAASYEKHLDTHDRYPRKRILDHARNLQAHLRKDADDPAAGRATESQLQTLSRVRQLRASVQMLASSASIMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3H3</accession>
    <name>A0AAD8Y3H3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_010297</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3H3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1738981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="59" mass="6841" checksum="B93F3279EB7FCE6B" modified="2024-05-29" version="1">MSVQVDATIMGKDMGHRNFEMVYLLGRCHLATDYTVLWHKSKMQKYPSIHKLGKPSFTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4I6</accession>
    <name>A0AAD8Y4I6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_010706</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4I6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1738676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="487" mass="54777" checksum="133DEDB1F1ECFD85" modified="2024-05-29" version="1">MTPLSDKEYINILAFIKMVVLNRHAKVEEEYCGLLGGGNASMNGATKSASMRHTAPAIARDSRFSTAILVCGVFLLGVLYGSHSSSNSSNNAVTTFPFNVAATLKSTTPRDVHVGSMCRCGSQKVPMPDVNKELISKYHQVPKNPLDMSIGGQDTRVIQPTSKATGSDPKRFLHHPVEGCQCFDGDGRIMPEPTSDQFMSKLSRDYFLRPNNQCQESEAESQFNWDQMPDFGVEDLPIFVGVLSFKSPLSLNNTLHNWLKHDLFHRIAAQDVMVQLNHRSQEDDEIMYDFQKKLNNRHPMTILGDEEENLHPGLAISNFCRRAEQHPSSHPNGENLVLFLEKDWIIPDGSGKLFYLESIFRSAIALSQRGVPYVSLRSSQVDGSKSWRCPAEGIGWRCTTAHQHRWTNHPVLISCNWFLRYLEPFVLLNDPIMYCGSSSVHRKRNGYCDWEEALQDGRVAWTNSQWVMAHLGNTGGGPLFVHHEVDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4W0</accession>
    <name>A0AAD8Y4W0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009520</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4W0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1739761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="786" mass="85042" checksum="8176A2E66322EAC0" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y598</accession>
    <name>A0AAD8Y598_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Trypsin-like serine protease</fullName>
            <ecNumber evidence="7">3.4.21.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_009730</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y598"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000002">
        <property type="entry name" value="Transmembrane protease serine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF91">
        <property type="entry name" value="AT26814P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="Peptidase S1" evidence="6">
        <location>
            <begin position="40"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1739971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="314" mass="34074" checksum="7777F2D6F03F6E50" modified="2024-05-29" version="1">MRPHDEQPQGAAPQPQQLRGSVDTPSQTQPPPFRPQQTRIVNGDIVAGKNSGYPFQVQVGGWLCGGSLIAPDVVLTAAHCIIGGSPSRVNIWDASRGRMTPRTVQSAVMHPRYKSDGLSDDIALIKLSEPALAVTADWDLVSNYDWGNHPPMIRLQRYQTPSGCTSLSQDQAGDITTMTVIGHGTVAYGGQMSGQLLEADVHYVQNSVCQKQYKNEDITDDMLCASDTQEGQDACSGDSGGPLFTRLPADGGHDLFTLVGTVSWGYGCAMKEYPGVYSRVAAKQIGLMKRYVEVSAQRVVMQMMERYEITPSSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5R2</accession>
    <name>A0AAD8Y5R2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5R2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="320" mass="34781" checksum="B844A79D899A9D15" modified="2024-05-29" version="1">MPRKSARKINPDGVADPLATQDEDQAALDAGEEATAAAMEAAAAAEAAEAAVDSLGLDGVGVDVHAADHGDDEMALAAAAAAAAVQAADGMAVVVDQALLATAAAAAASQVAASMPEQDETPTDFPQEVGDVSVPALPAPKLMDMDMDMDDDMYDPDAPEDERHDSLLAARRMKDRRRYATMSPTQRAAYNAHRRDLYHKQGETARHRRRERERQRYHSLEGEDQKARNARRAKLERDRYQKLSKDELGDRNRRRRERAKSRKTNAKRTESTQQMPVTAVMETQVPTLPATGLGMSAVAAEVAEQVIVNVMNDDDLQVQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6X4</accession>
    <name>A0AAD8Y6X4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6X4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="162"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="192" mass="21529" checksum="F5D83C8CA6753C26" modified="2024-05-29" version="1">MLSYCSLCERRLCVDCQKKKWCNGCEGDICMDCTDFTDCSGCGAGLCKDCIGNEGIESKCCKCEGHFCEDCNNQIYDRCNNCKMHICRDCDEEYNWLCCNFCQKCFCNECNEEKGTKAIQICDGCDTSSCCGDCRVLVLCQVYGETKDCTGCIHLAGPLLLEEVKKVKKEHAEEQIKELEEKMKQLLSGEGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y767</accession>
    <name>A0AAD8Y767_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial import inner membrane translocase subunit TIM22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y767"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041924313" description="Mitochondrial import inner membrane translocase subunit TIM22" evidence="1">
        <location>
            <begin position="24"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="175" mass="19124" checksum="C07B0949416456C9" modified="2024-05-29" version="1">MPPLRSFLLLLTLITLSIVPAHSQQRNYNHDGGLWGEVKRAADTIATPVEKVAHERYDKLSDRGKFVAGAAFGFGASRFAVCSTVNTVKTVGAAYIAFEALEYAGILKEARSTKEGDAIMAKTRDYLLRTADGIRCDIRTNLNPNAVKERIDRNMKRDKPGTTGFGTGAFLGFVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7F5</accession>
    <name>A0AAD8Y7F5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="6">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_008965</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="6">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7F5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="298"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="676"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="163"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="456"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="564"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="616"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="63"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="177"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="194"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="204"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="224"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="463"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="567"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="631"/>
            <end position="646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1740015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="979" mass="107932" checksum="8F414078466C00D3" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7R0</accession>
    <name>A0AAD8Y7R0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008813</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7R0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="184" mass="19667" checksum="55BB3D6143B79BD7" modified="2024-05-29" version="1">MPFFWFGGETTSSTAADGQAKSSSVAISSHHARKSSLSLSASSGQNARLAEVRSEATASYLQHQSIDMGGNHRRTQSGDISRRSRTSTGSGHGRKRGGVVAIEDDDDSKHKGRIDQGLIDACNEAKVSPTKASWWTSFSVTAITPSSFPDDTTSNVTASKLAPPNINEAALKHRRTVSKTTYRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7R9</accession>
    <name>A0AAD8Y7R9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TWIN LOV 1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_008649</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7R9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14809">
        <property type="entry name" value="bZIP_AUREO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47429">
        <property type="entry name" value="PROTEIN TWIN LOV 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47429:SF2">
        <property type="entry name" value="PROTEIN TWIN LOV 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0157">Chromophore</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="6">
        <location>
            <begin position="310"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="434"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="94"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="112"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1740554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="552" mass="60030" checksum="BA944593F4C26322" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y874</accession>
    <name>A0AAD8Y874_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Integrase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="785"/>
            <end position="842"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1393" mass="157188" checksum="83E69E1D718FA355" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8L9</accession>
    <name>A0AAD8Y8L9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007407</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8L9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010865">
        <property type="entry name" value="DUF1499"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07386">
        <property type="entry name" value="DUF1499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042165074" evidence="1">
        <location>
            <begin position="23"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="208" mass="22226" checksum="2DC2B1F8A86C5949" modified="2024-05-29" version="1">MMTSRSIVATVVAVFLCISANALVPNAHTNVPTRRDVLGQAASSFLAPLVIGTLPANALEGCGRASHNCIRTAWVAPASITTPEGVAQTIRDVLNTYPQKGQAGVDCNGWKIVNDALESDAAIITLEFKSCVGPAALAINLGQPFIDDLKLEIGKDASDKFKVNVLSKSRMGSTDVSVNRKRLIYLGNQLKEKGWSVPDPKYPYEMSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8M8</accession>
    <name>A0AAD8Y8M8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008886</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8M8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026913">
        <property type="entry name" value="METTL24"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32026:SF27">
        <property type="entry name" value="METHYLTRANSFERASE FKBM DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32026">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase FkbM" evidence="2">
        <location>
            <begin position="310"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="427" mass="48769" checksum="FF11E127E02F4FD8" modified="2024-05-29" version="1">MLLLLVDTSHDNVDFGCAGVANKVQSLCLWCKFFRREEGLYLYEGIYATRIRSRMKEDPPIAPAAAAHPQQEEPVPPVRLNRRWQLIINGGVSTVKICPSALKIFANKTELELAIQKNVHFHQHGGNLHSIEQYLNSHMQSTLDRLGVEFSPKDDLNKPVPNAIEHLNEYYKKNQIFRSALFEQRWINVIEPSTSQRFFAGIGPVGPNCSEPVSFSKGTYEEKSLCVEKKSKTHDNGGGERNDNDDDVDNKECHIVSIGSNDQWGFEEEVMKTPQLRGCVTHTFDCTLQNNKPKRKPQNDNVKFYPYCIGSEGQQPPYVPFDQMWNLTKTKQAPKFLKMDVEGFEYDVVINSILSSDSSIWPEQIMMEIHWATRMVDLVWMPRTRTAAELALFFGVLFNRGGYILQQVKYVRGCETCLEVLLVRAVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8T8</accession>
    <name>A0AAD8Y8T8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008397</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8T8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1741145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="106" mass="12304" checksum="90586A8FBD23AEDD" modified="2024-05-29" version="1">MDFRINCYFMKDSSQLLGYQSDLPPILSYKNIKPRAINICDDVHANVRRLLVDHGTDAAIWIKEYLMENPTVEIASPEYLCVCWIAGVLILVQLHREMVTFIYLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y945</accession>
    <name>A0AAD8Y945_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GTP-binding protein, GNL3/Grn1 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_007511</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y945"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050793">
        <property type="term" value="P:regulation of developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051239">
        <property type="term" value="P:regulation of multicellular organismal process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04178">
        <property type="entry name" value="Nucleostemin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1580.10:FF:000002">
        <property type="entry name" value="Guanine nucleotide-binding protein-like 3 (nucleolar)-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000571">
        <property type="entry name" value="Guanine nucleotide-binding protein-like NSN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014813">
        <property type="entry name" value="Gnl3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050755">
        <property type="entry name" value="TRAFAC_YlqF/YawG_RiboMat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089">
        <property type="entry name" value="GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089:SF30">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08701">
        <property type="entry name" value="GN3L_Grn1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CP-type G" evidence="7">
        <location>
            <begin position="142"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="22"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="503"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="73"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="219"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="507"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1741938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="537" mass="59113" checksum="2398C15F1B45C1DD" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9P4</accession>
    <name>A0AAD8Y9P4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_006951</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9P4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF10">
        <property type="entry name" value="SLC (SOLUTE CARRIER) HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="43"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="48"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1742386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="187" mass="19650" checksum="7F9B2713002CB4FD" modified="2024-05-29" version="1">MMIGQALIKSVAFSANALALESLTDFDWDSLGLGQVIGTPEQHAVISSSFLTLILAASFAGFVTSFLVTPVERVKVMMQAQSTNDGAYANELECIKAVLDNEGFLGLFSRGLVYGLLIHTSIAENNLGATAPLVCGAMSGCACWIPVYPIDVIKTLVQNTEGGDSSSAIDIAVQLYKDEGPGHSSTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9R5</accession>
    <name>A0AAD8Y9R5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9R5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="398" mass="45173" checksum="D210ECAF2169A193" modified="2024-05-29" version="1">MDPPAADKYLSRSTSSSRLWRSSKNAPVTGIVKGERQRLNYRRYCSQNGQNKMFLHRLCLCVILSALAPFVCFQFYFLYKLTNGKEDATERIAYQLGTRGDAIPEPEISPLDHFVPLPLPAEVPDWIPPNFHEWNYTNSTPPSVWFDALDTYGRRGYVADPTLLRKSVLQWHKDHPGATYWDRLKGYQSHLLKKIDDYLFMEKTCALIPGVSVFGQGGLTMLVERIKLDEVPTLRMGGKDCLKQEETPDADDGNNNTTKKKKLKLFCGVYSYDGQRDSTRLAALSYGIKCDGFLAFSTATIPSLGMVALMHRGNETYQNMFQKTRSILSYVATHYLDDYDYFHLGGDDMHVIVENMRSLMLVLEYEREGYSGNKEGRMFGQLAIKPRAGNLIFTGGPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YA04</accession>
    <name>A0AAD8YA04_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3067 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007104</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YA04"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.40">
        <property type="entry name" value="Protein of unknown function DUF3067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021420">
        <property type="entry name" value="DUF3067"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35126:SF1">
        <property type="entry name" value="DUF3067 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35126">
        <property type="entry name" value="SLR0598 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11267">
        <property type="entry name" value="DUF3067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042140827" evidence="1">
        <location>
            <begin position="16"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="224" mass="25748" checksum="0548AB14DFD7AA80" modified="2024-05-29" version="1">MKIIYATIFLPAAAAFVATSTPRRIQATFLQSSPFDEFLGNIFGKDEDKDKSRNKDSDIINDEEINISSFQQELTKRQQQQPQQELETDIDNAITDANKEEEEEEFDGYKMRDAIYNKFGECFDVDFNKVDAYGFRSVYLNIMPFRLGGKRFRHETELDYLCHLQAVVSTYLGGVEILQKYDQLDYVLAQLDETTKKPRAGTSPLIAVPLRLDLTEEQVNQIMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAS9</accession>
    <name>A0AAD8YAS9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosylphosphatidylinositol anchor attachment 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007489</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAS9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042765">
        <property type="term" value="C:GPI-anchor transamidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016255">
        <property type="term" value="P:attachment of GPI anchor to protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007246">
        <property type="entry name" value="Gaa1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13304">
        <property type="entry name" value="GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR ATTACHMENT 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13304:SF0">
        <property type="entry name" value="GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR ATTACHMENT 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04114">
        <property type="entry name" value="Gaa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="514"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="580"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="608"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="633"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="681" mass="74560" checksum="4B19237B5B49FCBD" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBS1</accession>
    <name>A0AAD8YBS1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006740</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBS1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1742175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="159" mass="17341" checksum="36DF9CB5722DAF9E" modified="2024-05-29" version="1">MKPRITANTAAPPSASSAVPLPPIVHAIGGSIGSALAILTFYPLERIRVEIQSQQQQKKPQKSTYRSAHRIWMLSETGDPLWEVLADQQQKQSNCATKISTGQNKTTTTLIVGNQLGYSADDEKLLIGSPSVREVSLGSLSLLTSQCISITHHYLDRIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YC25</accession>
    <name>A0AAD8YC25_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YC25"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="1">
        <location>
            <begin position="2"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="130" mass="14597" checksum="605A2E577769CC82" modified="2024-05-29" version="1">MKCCVDLGVGPSATQKEIKSAYREKAKLFHPDKPGGSAEMFRKIKDAQDELLASKRFKSCGRPQAFDGVLNGLGEHLRALSKQFMQEQRYDMAESLLFQLPALKELDNLVQPKLKSKEVQASVREIIKGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDP6</accession>
    <name>A0AAD8YDP6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_004886</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDP6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="262"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="267"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="271"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1744353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="303" mass="33748" checksum="2F513065F0C813D7" modified="2024-05-29" version="1">MSTQKAVKVIVFSGDKEHFPSWRLQFKAVAHLRGYNDILSGTRAVPTTSELANAPTAEVVQAGKDATAAYCDLLLSFPTTTKKGEVAFRIVVGAVNADHPEGNAKIAWDRLTEKYSPTNARSLIDLKSKWDKCYLDNRDPEEWITELCYIQTEMGKISITGATRVSDTDLILHILSRLPESYDTVTPLLHKDLDAGTLTIEGVRITLCERFKRIEDLEDSKVYSGTEQEEALVTLLKNATVEELKAALSASSGDAFKFKGTCYHCGKRGHRASDCNEKKNDTDDTVDDTENENSDEEVNYWLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDR5</accession>
    <name>A0AAD8YDR5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC1 kinase family protein</fullName>
            <ecNumber evidence="3">2.7.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004916</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.-.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDR5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05121">
        <property type="entry name" value="ABC1_ADCK3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051130">
        <property type="entry name" value="Mito_struct-func_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173">
        <property type="entry name" value="ABC1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173:SF12">
        <property type="entry name" value="PROTEIN KINASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041944641" evidence="1">
        <location>
            <begin position="21"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="2">
        <location>
            <begin position="143"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="2">
        <location>
            <begin position="253"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="489" mass="54503" checksum="E2DAF46AF696B314" modified="2024-05-29" version="1">MLQIIPPLALTALTLQLTTTYEQRYQCYTKAVANGERIIRAATFSLTIASIIRSYKRKSIELFFRNVVCCANKLTEEEEKLAWNEQHAQGADTLTKTITSMQGFYVKAAQIVASRPDSIPQEYADALSVFTDDNDPLPKELLDQRGEQFDDVFEEFDEAPLGSASIAQVHRAVLSKKYGHREVAVKVQRPSIEEKLMGDIANLKQVAKVFRGADLPVDYYAQESARHGLLEGVPLSRASDMMKSKGIAPDGVEAKLFARKLLKSLTTAFGWSILESGFFHADAHPGNIFVLDDGRIGLIDFGQVKQVDGTTRKSDDNDDDLHRIGNSTEGLDIELKDDAPAHGHAAIAMWLFDGSVETFPDGYDENEMSPNSPVKAMKEFPSDLVLLARSTVLVKGLARRFGVRWSLSQEWAPIARRVLNKGTDVTTKDTEEQKGQCKPHRAKQQLKAWSEQKAKTIVTHLPPPMKKKALSAVLKHQQKRDAKKQKVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDR6</accession>
    <name>A0AAD8YDR6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDR6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="200" mass="22216" checksum="3409DD9AD7C291F9" modified="2024-05-29" version="1">MLSVDEDPAVAEAAERNHEAEIFAGFSLQSNGIRFRAPTRGKTVQVFEERFNTQLVLEEVQVSDNDGKSGMTLRETVQVSPGLTVLRSIYSVMAVFMGGFLFILGFDILLFLFIHLVSVFNENQGIGIADFVASFFSVPVFVYSLAFAMTLVTSFVVDTFYGNPFIRSFGLGVVFTEWMAFIFYLGVPLLTFIATLFMGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFV9</accession>
    <name>A0AAD8YFV9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Sodium/hydrogen exchanger family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_003991</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFV9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43562">
        <property type="entry name" value="NAPA-TYPE SODIUM/HYDROGEN ANTIPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43562:SF3">
        <property type="entry name" value="SODIUM ION_PROTON EXCHANGER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0050">Antiport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0915">Sodium</keyword>
    <keyword evidence="9" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="162"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="331"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="447"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="479"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="12">
        <location>
            <begin position="127"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="720"/>
            <end position="781"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1744700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="862" mass="94349" checksum="3BC50108411E8CA5" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YG98</accession>
    <name>A0AAD8YG98_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_003642</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YG98"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="155"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="260"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="290"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="354"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="494"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="606"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="606"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1745718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="629" mass="69999" checksum="9B552153A7D98C19" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHH4</accession>
    <name>A0AAD8YHH4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine--tRNA ligase, cytoplasmic</fullName>
            <ecNumber evidence="2">6.1.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_004567</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>tRNA(His) + L-histidine + ATP = L-histidyl-tRNA(His) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17313"/>
            <dbReference type="Rhea" id="RHEA-COMP:9665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9689"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78527"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.21" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHH4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004821">
        <property type="term" value="F:histidine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006427">
        <property type="term" value="P:histidyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00773">
        <property type="entry name" value="HisRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000061">
        <property type="entry name" value="Histidine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000012">
        <property type="entry name" value="Histidine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015807">
        <property type="entry name" value="His-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004516">
        <property type="entry name" value="HisRS/HisZ"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00442">
        <property type="entry name" value="hisS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11476:SF7">
        <property type="entry name" value="HISTIDINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11476">
        <property type="entry name" value="HISTIDYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001549">
        <property type="entry name" value="His-tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="10">
        <location>
            <begin position="1"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="61"/>
            <end position="63"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="262"/>
            <end position="263"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001549-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1745276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="446" mass="49905" checksum="0D657B161251F7C9" modified="2024-05-29" version="1">MAIRDKAFTIIRRVFKRHGAVEIDTPVFELKETLTGKYGEDSKLIYDLADQGGELLALRYDLTVPFARFLAVNAVGNIKRFHIGKVYRRDQPQLSKGRYREFYQCDFDIAGVYGRMVPDSECLAVACEILDSLPIGDFGIKLNHRRLLDAILDLCGVPADKFRTICSAVDKLDKEPWSEVRREMVEEKGLSGDVADKIGEFVVLKGKPWDLYNSLMESKSFGNHKGASEAMEDLRILFEYLEAMGKLKFISFDLSLARGLDYYTGVIYEAVCMNGNTQVGSIGGGGRYDTLVSMFQEAGKVTPCVGVSVGIERVFTLMEERLRQEQGGSIKQPNVTVLVASAGDNMLRERMKLTNVLWDANISAEFSQQENPKLKFEIANALDRQIPFMVIVGEEETKQGKCKVKDLNARTEDTVDVSDLVKTLRSKGVVPVGCEFAMEMLNSESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHI9</accession>
    <name>A0AAD8YHI9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Deoxyribodipyrimidine photo-lyase</fullName>
            <ecNumber evidence="2">4.1.99.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.3" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHI9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003904">
        <property type="term" value="F:deoxyribodipyrimidine photo-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052219">
        <property type="entry name" value="Photolyase_Class-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10211:SF0">
        <property type="entry name" value="DEOXYRIBODIPYRIMIDINE PHOTO-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10211">
        <property type="entry name" value="DEOXYRIBODIPYRIMIDINE PHOTOLYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="Cryptochrome/photolyase FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="Cryptochrome/photolyase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="1">
        <location>
            <begin position="37"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="447" mass="49138" checksum="D5A0E71AF9D56823" modified="2024-05-29" version="1">MTVLSQLQLSSCLRSRINHDTAAAVSAAEVADDPSTGFVLYLPTVNLRLEHNPAFAVACHAANHLKLPLVVLAVVCDDASHHSNSPLGNGGVVMTSRRLAFTLQALSHACNQWSRHGAAVGVRVHGPNGARVPDHLTLASNASFVVTDESFVSPYTTITRRVKEACRKSKVQCISVDGSTTVPPIQVLKRNRNQDAHLKAAMQGEFCAPELRIKLEDEDLFHPILDNGVSSSPTLAEKLAHLFPRRWKPTSLAYSDNQLHSLPSCPDVRPFTSAELNSLFRNDDHYKNNEATTVAAAAAAAYQSQLKSEDSSVPFFNFSMQWNGADHTVPPCEHTIGTSPCGMSRWNAFVQKGGLLRYGKERNNAKLVHSVSRMSAYLNLGIVSIFRLVSEVKRAQRQAQGNMSHKSCIDKFLQEIVKFERYPTLMHFLVGRTTMALEAFLDGVCRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHR9</accession>
    <name>A0AAD8YHR9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF1295 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHR9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010721">
        <property type="entry name" value="UstE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251:SF15">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE (DUF1295)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06966">
        <property type="entry name" value="DUF1295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="254" mass="28343" checksum="42F6248A7DA3AEF6" modified="2024-05-29" version="1">MAGQGFVYGIAAAITCVIQLTGYAVAYSLKTETFYDILGGVNYLALALWSAIAGSIDAPLNWVDDPRKILVTILFMCSRGWLLIFLAWRAHERKGDSRFDEVLGKGGGQPQPFGFFVFWMAQAFWVFLISLPMLFVNSSQVNKPGFSAFDIAFAILFCAGVLIEILADIQKALWVKRGRKGDFCTDGVWAVSRHPNYFGEIFQWWCLFAFSYSSSSNNGYADPLWWVGILSPLFTMQILLTMEPTGLCNAEGRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJ35</accession>
    <name>A0AAD8YJ35_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sulfotransferase family protein</fullName>
            <ecNumber evidence="6">2.8.2.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_001482</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.2.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJ35"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037359">
        <property type="entry name" value="NST/OST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10605:SF56">
        <property type="entry name" value="BIFUNCTIONAL HEPARAN SULFATE N-DEACETYLASE_N-SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10605">
        <property type="entry name" value="HEPARAN SULFATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sulfotransferase" evidence="5">
        <location>
            <begin position="30"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="236"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="238"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>3'-phosphoadenylyl sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>3'-phosphoadenylyl sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR637359-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1747519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="303" mass="34983" checksum="F29B4950669E3899" modified="2024-05-29" version="1">MHSNKRKNADFELTFLGIGAQKAVYDISLPQEQKEVHFWDWHYRKGFEWYIRQFGYHSQKASSASAPHYGEITPCYVVLPEATIAELYKCFPNLKIIFVARDLVDRAWSAMIMELRDQTMGLSAGEFANGVTGTDKNNNSNHANKRTKLSAAQQRRFYFMDRLRNATHDSRSNYAKHLSNWYKHFPSSSILLIDYREIESNPRDVLLKVAMHIGVEEEQAKQFVTSLNDKEVGQRVNAATSSGSGASTVSSSTSSHQLLTQRPMLKKQMERYLQPYARDFNDMLKTKGYDWRLDDFSLKKEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJ94</accession>
    <name>A0AAD8YJ94_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 7">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="1 7">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_001569</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="1 7"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004435">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate phospholipase C activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051209">
        <property type="term" value="P:release of sequestered calcium ion into cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00275">
        <property type="entry name" value="C2_PLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08558">
        <property type="entry name" value="PI-PLCc_eukaryota"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF36">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00387">
        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="2 7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="5 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="701"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="domain" description="PI-PLC Y-box" evidence="10">
        <location>
            <begin position="1052"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="9">
        <location>
            <begin position="1153"/>
            <end position="1280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="340"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="15"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1747606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1307" mass="146645" checksum="0A508CCA4BFC87AD" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJF0</accession>
    <name>A0AAD8YJF0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002452</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJF0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="424" mass="46587" checksum="8C89A0D8811DA71A" modified="2024-05-29" version="1">MVVKLPDHWINEEYIDSPRRTVTTPRSGGGGFGSGGITTPRGGNTPNRFTPNRSQLPPLAWGTPRSGNSRVGSRTGSPEHHGHYGSMSGTPRVRASPLPKQLNRVVSDTQLNKTAGDDDGTTPQEERVEEQFLVAAARSIPNEYGTPLASYFVRRPHVTDDSLEKNETDELAKLAIDLWGNKCTHLSSSDDYKKYASVFKPESLEIVACIEADGSVFTLSGECNARHGKVSTMSSNNGSFDEDDSNIVDKEYDWSVFDNVEEMDRALGRVSYIDEEGNEREYWLDSIYEEALTTRESYCTSMISAAFTLKEVRGPLAQKREQPASWNQTMQSQPAPTQTFQSFAPPKSTVEGSVNMSHPPMNQQNVPQSNANAPQTQSQRSEPVSKVEMPSNPARKEPLSAAAATKAIAPKKRQTEAITTTRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJK0</accession>
    <name>A0AAD8YJK0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002862</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJK0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="176" mass="19868" checksum="F59404C661D2E908" modified="2024-05-29" version="1">MSAITNNSNSSAKPTTTTKRTTFKQKIRQYAALFDGSNKDFSDIESAFDDLYHDDFLGTESNGEEVNKETKKQLDEKRLAAGAKVTHVAYTRTDWNKALVKYHLEIDGKSIISKYLVTIKDKKVIEAQYVNGFAGMVKAAWVSDFHLIRRVQSYQHVDKVVFEGYVSPFADLTAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKK3</accession>
    <name>A0AAD8YKK3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKK3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36971:SF1">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36971">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="186" mass="21130" checksum="66D17140038B3A44" modified="2024-05-29" version="1">MRQSKSPRHLRCFLDGEACVEFMNAASEEDVHRADEWYQHQLTRAKEISWTSRGLTQHEDGSSYHEEEATNNDETKSSETIDTCTESEISSAQEARNVLQKSHLIVGLHCDQAAGEIVDFASAKNIPWCVVPCCTYSEMFSCRKLADGTRVTSYDHLVQWLQERDPRAKVATLDMEGKNKVVYTLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKS4</accession>
    <name>A0AAD8YKS4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001806</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKS4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="90"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="303" mass="34193" checksum="7981325692323A98" modified="2024-05-29" version="1">MLYFRLNANYLAAAFVALYFLSRFFFKPSINTVKTHNAPSSSTIYKGTTWWSDRTVAVRTVAETSFARCDIHTVVSEDGQKVFNDWIFLEEVNAVNIVVQTAEGKFVVFKQYKYAVPGETFSPVGGFVDDGEHPWTSAKREVLEELGLGSSATLERVNTNFGNRDDRFRNDPKRMRNVVIDIIQHDAIQPTFDEFDIPEGHIPTSDDPDWVFLGRYRTAVNRGGGFTYLYLLKNAVPLLPNGGSELYAGTGDDEQQSIMHLSVHEVFDFLSQAKFQEVKWTATFALSLLHINNGMPSCCGEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YL24</accession>
    <name>A0AAD8YL24_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YL24"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="106" mass="11319" checksum="B4F713900AD21A07" modified="2024-05-29" version="1">MCSDIGTTSRVCAMYSFTGIIFTLYVGVLLQTQPFFITGIDDISTAKSNAFGAMGMFIATFGISLFGIMRTSDDKSDDLEGEGFQLGTVTSVSSRSAGDYAASRYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLN8</accession>
    <name>A0AAD8YLN8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000612</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLN8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="40"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="253" mass="28214" checksum="5AC1C3065A8C7E3E" modified="2024-05-29" version="1">MMVQFEKRNNSAAELRGGPQDEAAARISALSGFEALCYTDADLQERLNEALDENKKNEATIMKLREQIHRHQAQERSMAAQIIQLSMDLAMAKAEADRQQLKLSPLEQQPQECILHTALKSAPKESNQIAPLDRVPCRTRSRHLRSQSLTISSNFVAHMVDMDVDTEDTVSNNNMGSNSNLFLSMGRRIGNLDSSFRSLRQSVLMGSMHSESSSEKIKSLSGSMNKSLHSIATDGPFDCDNNSSIDWPDEVPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLP7</accession>
    <name>A0AAD8YLP7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional dTDP-4-dehydrorhamnose 3,5-epimerase/dTDP-4-dehydrorhamnose reductase</fullName>
            <ecNumber evidence="2">5.1.3.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000232</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.13" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLP7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048269">
        <property type="term" value="C:methionine adenosyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008830">
        <property type="term" value="F:dTDP-4-dehydrorhamnose 3,5-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048270">
        <property type="term" value="F:methionine adenosyltransferase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006556">
        <property type="term" value="P:S-adenosylmethionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005913">
        <property type="entry name" value="dTDP_dehydrorham_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491">
        <property type="entry name" value="DTDP-4-DEHYDRORHAMNOSE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491:SF4">
        <property type="entry name" value="METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RmlD-like substrate binding" evidence="1">
        <location>
            <begin position="30"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="332" mass="37518" checksum="2FF4B8B72D5B07C7" modified="2024-05-29" version="1" fragment="single">HSASLVRFDLTMTDRNKSNIKMSAPITKALIYGGKTGWIGGKVAVMLKEQGAEVVLAEARCENRADVAKELDEVKPSHVFMAAGITGRPNIDWCEDHKPDTIRTNVIGTLNLADLTNERNIHCTVYATGCIFKYDDAHALGSGIGFTEEDTPNFDESFYSQTKGYMEPMLKCYPNCMILRVRMPISDDLIHRNFITKIVKYERVVNIPNSMTVLYEMLPASLAMAKKGLTGVYNFCNPGVISHNQCLDLYKKYIDPTYTYKNFTIEEQSKVLKAGRSNNELDSTKLMRDMPEDIKINDILTAVELCMQRMQKNLTEEFGPLPDSLPKEFRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLX5</accession>
    <name>A0AAD8YLX5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Adenosine 3'-phospho 5'-phosphosulfate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000955</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLX5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="22"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1749016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="142" mass="16171" checksum="467C4B0874F57B11" modified="2024-05-29" version="1">MENRPLLSPTAEAALLELSTNFLLYCAMVLITTMVAKIYFPSWLEPREAPTPQLSHNYMDVIRDSYKSDLSDEDEDEDEEELMGGLLNRTEEGEHNNPESSDEGATSLRRASSSSHIFDYDQSSESKQEYTQTWQFVQSCST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YM27</accession>
    <name>A0AAD8YM27_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Digalactosyldiacylglycerol synthase</fullName>
            <ecNumber evidence="8">2.4.1.241</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_001673</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.241" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YM27"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046481">
        <property type="term" value="F:digalactosyldiacylglycerol synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01635">
        <property type="entry name" value="Glycosyltransferase_GTB-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044525">
        <property type="entry name" value="DGDG1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46132">
        <property type="entry name" value="DIGALACTOSYLDIACYLGLYCEROL SYNTHASE 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46132:SF1">
        <property type="entry name" value="DIGALACTOSYLDIACYLGLYCEROL SYNTHASE 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1747710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="437" mass="49613" checksum="FBCF25A622E5DFFB" modified="2024-05-29" version="1">MCYSTQPNRRYLLSDAVCVLEEPEHLNWYRCPGEGWTKVFGFVVGIVHTNYVEYASSQFIHGLWTAPAIQVMSSAMIRAYCHKVIKLSGVLQTYAPEKECCENVHGVRQDFIQEGRRRALEAASLSGTNSASSELNEEIEGQVYFIGKILWAKGFELMLQLQEFYHECTGKYFAIDVYGGGPEEGEIKRAFHGRRNSWNGEESDSDSDLEDTFRDNLKKLKSIEVPKSLYEWRRKPIPANFCGPVDHSLLGKYKTFVNPSTSEVLCTTTFEALAMGKFVIIPVHESNKFFLQFPNCLSYRNKWEFAANLRWALTHEPEPLTPELAKEFTWEAATDRLIRSSAITRREAKERYNLGKAKLDERIAYFHRELGKHDALRRVLGGGPASNQVRYELERQGLDQGNSEKFAMSSFVKAIKSTFISNNHHSQAASLSGGSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YP88</accession>
    <name>A0AAD8YP88_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acetylornithine deacetylase</fullName>
            <ecNumber evidence="9">3.5.1.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_000575</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M20A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.16" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YP88"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008777">
        <property type="term" value="F:acetylornithine deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010182">
        <property type="entry name" value="ArgE/DapE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050072">
        <property type="entry name" value="Peptidase_M20A"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01910">
        <property type="entry name" value="DapE-ArgE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43808">
        <property type="entry name" value="ACETYLORNITHINE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43808:SF25">
        <property type="entry name" value="PEPTIDASE M20 DIMERISATION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0170">Cobalt</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="8">
        <location>
            <begin position="237"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1748636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="482" mass="52057" checksum="B3BC44504421A585" modified="2024-05-29" version="1">MSAAHELVLSDEIVSAVDAIQGEATEFLKTIVAIDSTLDKGEEEVQTTILKLLQETLGSGADVEASGAKSTQPNCFDVERIPVILDKIKDKRGFSPVDWNYDESKFNVVASYQGGSSDGSEGSNKALLLQGHVDVVPANESDGWTHPPFSPIIKDGRMYGRGSGDMKAGVVAMIYAVIALRRIGYLPRTNLTICTVIEEECTGNGALAANHTSLLPFSDTTKTAVIIPEPFNFIVNAQMGVLWFNAKITGKPCHVLQTSAGSNAIEGAFSLFAALKVLEEKYNEPSNRHAVYEGIDHPVNFNLGKIEGGNWASSVPSSCRFEARVGFWPGIKIEDVKRDIESTLNDEANKLGLGLEIAYRGFQADGAILLPDFVGGEASGKKSLQTDFVDSLQKCYKTASAGDESNAGRKLLIKPITCTCDARFYSNLYQNSGNVVVTCVGPESDSIHGVDESVSLKSFRDCMVTIALFINEWCGLEKEETQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPC1</accession>
    <name>A0AAD8YPC1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF5880 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000759</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPC1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043653">
        <property type="entry name" value="DUF5880"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19208">
        <property type="entry name" value="DUF5880"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5880" evidence="2">
        <location>
            <begin position="94"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="445" mass="50089" checksum="AA93AAA32DEAA6FD" modified="2024-05-29" version="1">MSEALGGIDIGRVMSSDGPIVNEDDVNEMSIREMKQELESFGVDTSQFVEKPDLRNALTEARLNSKKPASSDGKDGGNDEYTFRGESVPLLRYMEEIEVDTTPKKSMVAQVLGGDFTFLGQYEDEGIMVMVRRPDWEDEDSSFDESDIPPVNPHPLQPPFDEIEVRGDILLIRVAETAEELDVMNDNDDEEEEDSKEQGEIVSDLKPAAAEEKEEHEEKLVSVPANDEFFLDYSKEEYLKFASRTDVEGPPILEESEESSEEENEEEAGTAKADGDEDEDYDPEVEELSDEEYDDEEHQVGMMNLILGQILRKFHEENGRGPDTLELLEMRKALADRLGVEVPPVDEEACDWDKKAPTPKKPTPKKVVVAEERNECETFPREASNLFPSENDEEAVDDQDESSGLKRPVEMIYGEQDEEDDDDIQHQSKKASLCKESGKEGEVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D408</accession>
    <name>A0AAD9D408_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_017043</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000077">
        <property type="protein sequence ID" value="KAK1732268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D408"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="231" mass="24623" checksum="6F0ABEA125846537" modified="2024-05-29" version="1">MVKLFNPPTAAFMLPTGGGVSHRLQAVPEHIIDALSPVSLPAQLISSSDFGETVAIQQTTSSTSPQVFEAVLPDSSLLIGMGSVVLLCIVAGFVWANEVVPVSRTKLAISKSRGEVRGYLDDLSGSSSIDDDGIELNATMIAEGAEQQINESTNNNDEMIKPNVGDGRDFERWLFSDWLNSNKSKGGRQKEPALPILKKAKWNSGDNPVLVTAAIMMLGVVVASVTERIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D467</accession>
    <name>A0AAD9D467_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000054">
        <property type="protein sequence ID" value="KAK1733092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D467"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="387" mass="43965" checksum="CB49B7496382115E" modified="2024-05-29" version="1">MPFFHSRYLKDDKKASAVGEASQISEPKSPSNKIWKQSTSKKGSQPSSPQQERPTSPSSPRLVWHSNVGSSRKTQAKKLFSAFQYNDPSKKKTVHFATIEVQQYNWDYTCDPDVYYLKKQIAAMNKQRFTDASKIRKQRNIKLPSKKDKEKAKKACDDVDIAKRATDITQLLQEAFDPERDTDEQVSICGIEHFVYPALQKEMIQRKKQAQREVINFNKPNPQGWRLARLCEANTKWARDVAVEKGKRYCVNHETMNKRQVWKRSRRSSMSDMGRADTGELLHRLGRSEPVFKMPEREAAAPTGAVGMFQQSDEQGKSKATPEQEAVAPTGAVGMFQQSDEQGNIKATPEQEAVAPTGAVGMFQQSDEQGIIKATPDESWKNKFDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D591</accession>
    <name>A0AAD9D591_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Right handed beta helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015939</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000050">
        <property type="protein sequence ID" value="KAK1733380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D591"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="452" mass="48283" checksum="526E929A6F1B58B4" modified="2024-05-29" version="1">MSSQAKVDGSTAQLDMEDQPPSLPTPPKRQKASSFSNISRILVFALGIFIVGSIGFAGYSAFASRDIQQQNAVAVIREGPDNQGKAGKTPPPVCGSTVQCGGEAYTGEVKLTEDLFCTDTETPPIGGDICDICAITLDGEDAELDCNEFMVHNSGALFNGICLLNGARAKNCYVQKFLVGIYVQNGGEVNDCEVMFNDVFGIQVQNEASSTTKMKISNTYIHDNSDRGFYFLGSGESPESSETSIEVNNVKSNHNVIGMSFAGDNVKLEVQVKDSETSNNSGSGIEIDSVFGVNISAAVDVELDGIISRYNGDHGLFVSPLIVGGEVKVKVKGDVNLYKNENSGFFVGDVDVVVERRGALNSCGNLASGSLDEDIRSDGLATFSGNGYTCDSTSPIYSTSSPVILAPTAPSDDVLIDVHECPFPNNIVNRTNLSRQQRIMIRMFCSIFIHNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5D3</accession>
    <name>A0AAD9D5D3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Leucine-rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015716</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000047">
        <property type="protein sequence ID" value="KAK1733543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5D3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="233" mass="26254" checksum="745EAC17ABC10CAD" modified="2024-05-29" version="1" fragment="single">MADQAVEDDIFVYTGGRAPQHVVNVIIDESVSEIDDMAFYDNRNLRCVSCHEGVEIIGLYAFFKCPLLRRIELLGVKLILEKAFYECRGLEDVEFGDVLETVEDGAFNQCIFSSCITFQSVRSIGNASFWGCTGITDVEFSENLERIGRYAFAGCSNLRRVAIPLKDGILLFPYVSSNLPKCTQFHRTKNLATVDLVGRVHKTVASLHLESWRNEMNEEIDRINRVLPTTGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6A3</accession>
    <name>A0AAD9D6A3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tc1-like transposase DDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_013849</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6A3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1735686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="370" mass="42695" checksum="C79011128DAC7D66" modified="2024-05-29" version="1">MVDYDMIEAIVEKMRGVKIKDRPHASRGGRAYPKEVREMVIEMMLSGGIATVKSQVVKQLRAQKKFPVLQTCRRWLRQHLMRGHVLPKRKTGNKVATREITGEALVQLALYRVVRPHARLYEVRAYLANRFPNVKPYSNSQICRAEQRLGLSRKAASSTSQEAYSPKNLMKRKMYWEYPYPLGVAGEKTADIIDIDEARFKLESADRSYGKVAREFRCNLKGRYKKGDPGTNLILAISGDDHNPISFHQQFTEGGTDLFRFYCFMSDLIDFLEENYPNRSFLFTMDNLNIHKHPIILNLIEDAGHRIVFRAPYWSCDGSIEYAFNTIHTILEMSGDKMENVDALVNRINLIIGSLGSFRRYFLHVGFQDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6F2</accession>
    <name>A0AAD9D6F2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TraB domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014542</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6F2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14726">
        <property type="entry name" value="TraB_PrgY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002816">
        <property type="entry name" value="TraB/PrgY/GumN_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046345">
        <property type="entry name" value="TraB_PrgY-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21530">
        <property type="entry name" value="PHEROMONE SHUTDOWN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21530:SF7">
        <property type="entry name" value="TRAB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01963">
        <property type="entry name" value="TraB_PrgY_gumN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041919082" evidence="2">
        <location>
            <begin position="27"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="388" mass="43269" checksum="194CFC60112DBC4F" modified="2024-05-29" version="1">MATSTLVLLLCSIILASLLCSVSSHAATSLSYSSQTTNTEEGWRESLPTKLRDNQGAPLHRVIIQPQAWSKSCTGNATVTIYLLGTSHVSRTSCQDAELLMDHVRPDCLFVELCSQRVGLMLPAHEATPDVGDEKQTHNKQQQRGMSPISHKSAGLFAKIQNDYASKLNVTIGGEFKTAFQSALRQQREFWNSRQNYYLNVNNGIGHPRANRPCAIVLGDRPVRITLLRAWESLRLFGKIKLVLALLWSSIKQPSEKELREWMESILNDRTGKSDLMKKAMDEMAKSFPTLKRVIIDERDEFMVAKIKQTAELLACSTSTDGERVMVAVIGAGHCNGIIEKLLDTKPSPQPEEILPSITRTKRKAEDDFEGSDVVQFDYAYAIETGMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6K0</accession>
    <name>A0AAD9D6K0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013167</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6K0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="121"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="213"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="364"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="523"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="681"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="755"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1023"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="222"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="263"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="384"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="416"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="445"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="523"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="550"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="562"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="587"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="601"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="613"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="633"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1134" mass="126256" checksum="4A0484A7970FFEF0" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6L0</accession>
    <name>A0AAD9D6L0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_013513</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6L0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1735807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="447" mass="50019" checksum="850A706B7C45757F" modified="2024-05-29" version="1">MDEFSLRWMIAESQREHQEFYQKLMRAEMNDPTLTEMTFGHFGHFVHVMDEEEFESFGETIARNTHIKVLFLGDHNLGDENMQALFRGLTRSSSIEELNFSSNRIGTETIRSMVPFLQNASNLKKLYVSGNNITSEGFKVLWRELTSSQIEELHCAGCGVASIEIDIGSIPPNLEKMSMSRNNINTDGCRELAKLLQCKNSALTELLLVESRIDDEGVAILVDALENNTSLEKLTLQKNEGITMKGKALLLKLVNDVSSIAATLQSNHTLQKLTVDEDSNIQRHINHAVDYHVDEANDPEEAGREKVIQTQLNSVERAELVALQGVDCSLSLYSEIDPLYLPEVLELVQEYHGMSELYVALKSSAPGLISIVNRKEYILQQRAYHAALVAEHAGIVDDLDAELAVIEEGSQVAVSGSKKRRRTALDEVQIDVSNGKADHDLTYQSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7U1</accession>
    <name>A0AAD9D7U1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007058</name>
        <name evidence="2" type="ORF">QTG54_013231</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7U1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="120" mass="13672" checksum="5A800AE907EDFD67" modified="2024-05-29" version="1">MISLDWICGQCAFIYAFNKIKPAVIVDKLIEAVVDVLVPGKGAGESNWFWRNLRSLERDSDRISKELDIRGELRNWDSEFPFFHHELIVRYAAGFLASAVAVAAFGQVRSLFSSSKRSRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7Z7</accession>
    <name>A0AAD9D7Z7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6824 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007128</name>
        <name evidence="2" type="ORF">QTG54_013305</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7Z7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049227">
        <property type="entry name" value="DUF6824"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20710">
        <property type="entry name" value="DUF6824"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6824" evidence="1">
        <location>
            <begin position="124"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="239" mass="25645" checksum="7B061910DA80FC89" modified="2024-05-29" version="1">MESRDVIMKQIASQAAQVRHTFEASSKKRHANVSSATAAAALHMANLNKRRKLEKSILSNDEGGAPLPSTSNGHTSNGHYFHSAIASFTRPEPKKPIIDNSSSNISDGITVKSQAGDIVVSPNDVIQGNGKTTQSLVGNKRYRVWIDLHSASFAKALSQEERVQIATSVVNTVTSSAPRGKFLSMDITSGLWYEMGQESAVNMTMGALLQCTAAHSPVAVQMPPQQAAVQRKTFVSRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D840</accession>
    <name>A0AAD9D840_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_011818</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D840"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="318"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1737532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="461" mass="52370" checksum="9FD60BACE8F14AFE" modified="2024-05-29" version="1">MATDFKEIMEVLMKVVNGGENPTETIGHDTWLPEKRAKYNAKRRQKDLDFVYSNWGLPQEKLETKINIADVPAKVAKKHKRAVAVHGYEWARMDKEYSVKVKEMESRGSLAEAVSYSIAHGTSTLEQMQQVLPTYQSRTIVDIPPDFRKFSSRICEREISGNCSALNYLFRNNYYLASYYNYAGERTDDELSLHHVNEALSLLPTLQRGEVPHYDEVLVRTIRALATYCMKDFEAALMEYRVCIAAIRLLHHEGRIDMSDATDKLMNTVNLWPHSILRMTIRIKIQNGVSRPYLTKEEYLDLMKENAYGIYSPSSQKCFHCGNTEKLLLCCGCSNAWYCSKSCATKEWKIDHKRRCGSKRYTGTVTMTASCLQEVLDEIESKDVGPETVNSLGMSILNFGDRDFLVLCKDPSSGEIFDALTDETIEMQEGAPLPTLKSKLGGYHVFSGVPSNKSSQAESQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D869</accession>
    <name>A0AAD9D869_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Leucine-rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011155</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D869"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="300" mass="33421" checksum="DB72494EAF0AE7C1" modified="2024-05-29" version="1">MNYITMAAEGDVIEYLYTAEDPDVIVPRDAIHVIVANSATVIWFAAFREHPKIATLFCPVGVETIEDGAFFQCRCLRRVIMLGVREIETAAFGGCEALTDIECGKLEIIGRKAFFECKSLRIIDLSAAKIIQWHAFQRCSALMDVKFGKELETIGYGAFNNCTSLQRITIPLKDNMIADDNIFDGCDNLKHVDLVEGAILKETITALQLEGWRNDMNAEIDAINQILPLAPAGMSKGSKGRMIRTWIRAVVGKIVHYKIQHSRLLNEAATALELAIPKDIVIKNVLPFLELPSYAFEGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9V1</accession>
    <name>A0AAD9D9V1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">60S acidic ribosomal protein P1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_009995</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein P1/P2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9V1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038716">
        <property type="entry name" value="P1/P2_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="79"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="94"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1739452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="121" mass="11182" checksum="A33F6FDD6435C174" modified="2024-05-29" version="1">MVVSSLEGLSDAQKQELVASLSAVVVGSAGADVSADSLSAVATASGNSLSGAWASVFATAVSKAGSIDKYCLAPGGGGGGGGGGGGGAAAAEEAAPEEEEVEEAPPAVDMFGSGGGDGGDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DA12</accession>
    <name>A0AAD9DA12_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">YjlB-like cupin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_010834</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DA12"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02219">
        <property type="entry name" value="cupin_YjlB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047121">
        <property type="entry name" value="YjiB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36448">
        <property type="entry name" value="BLR7373 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36448:SF2">
        <property type="entry name" value="CUPIN TYPE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1738165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="202" mass="22803" checksum="60435E8433F85EAF" modified="2024-05-29" version="1">MTKTSSFQRQWGKVIKVMSSSTSSASPSFDILQIFMKDDGTFPNNEHYPTLIYKHAFHGSESEGRRLIVNKNEWTEPWVWGIFSYHHYHTKAWELLLCVCGSASIQLGGDDGPTVKIDKGDLVLIPPGVAHKQLEEGGGFSLLGSYPTFRFDGRIDTCRGKPTDEERRRIQECYVPEADPMFNLNIAEFCSSSAQWSESDLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAG2</accession>
    <name>A0AAD9DAG2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAG2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="75" mass="8926" checksum="375370D97B0DE91A" modified="2024-05-29" version="1">MSGILQKRRFQSTPYVKRDTNRPRNKANECIWENRAVLEKIDRYLLETVPYYQFCNDCMGSENEITATVAEYNNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAH7</accession>
    <name>A0AAD9DAH7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">CCR4-NOT transcription complex subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_010245</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CNOT2/3/5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAH7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1020">
        <property type="entry name" value="CCR4-NOT complex subunit 2/3/5, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038635">
        <property type="entry name" value="CCR4-NOT_su2/3/5_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040168">
        <property type="entry name" value="Not2/3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007282">
        <property type="entry name" value="NOT2/3/5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23326">
        <property type="entry name" value="CCR4 NOT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04153">
        <property type="entry name" value="NOT2_3_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NOT2/NOT3/NOT5 C-terminal" evidence="4">
        <location>
            <begin position="29"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1738929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="141" mass="16162" checksum="A9BC407C35D9B2A9" modified="2024-05-29" version="1">MTDADRNRLALGSDLTVLGLNLNSNDNLYSTFGGPFSDKPATREPHYQLPMCYYMQPPALKTGHLSKFQLETLFYIFYALPKDVLQAYAAQELYTRDWRYHVESKVWFKQATPSDVPNGNVAAGQYIYFDINTWDVDCTVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAU5</accession>
    <name>A0AAD9DAU5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DnaJ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_008776</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAU5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051434">
        <property type="entry name" value="DnaJ_C_subfamily_member5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44027">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44027:SF7">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0564">Palmitate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="230"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="592"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="633"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="8">
        <location>
            <begin position="32"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="427"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="667"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="427"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="668"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="742"/>
            <end position="754"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1740681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="754" mass="84681" checksum="1D346BA4F492E758" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBA8</accession>
    <name>A0AAD9DBA8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010058</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBA8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="269" mass="29826" checksum="9088CD884A07E525" modified="2024-05-29" version="1">MENVVNSNAIATANMQAAGTTGLKNKKSSKSKKKKSSTRPKLRPVETLPSVEDDEDNLERDGLGYGDIMVVPPPTPRDKLFSDMYRLEQDITTLPKFSDEWFGVKAELAVVQMKLDDWDNSTPTAKGGRMETPVVTTNAAYQDIIKHISNEEESQQQQPSSEWQPVNKKKKNKKSSRKKNRPKLTPQSVEKKEEGDEEDGLGFNDILLTKKQSNKAPVVVVDEHTTLLVDGGGSTVVAPQPQSNAVGDWLLRGVIGTMFCILVFKFLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBL7</accession>
    <name>A0AAD9DBL7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">branched-chain-amino-acid transaminase</fullName>
            <ecNumber evidence="3">2.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_009587</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBL7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004084">
        <property type="term" value="F:branched-chain-amino-acid transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009082">
        <property type="term" value="P:branched-chain amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01557">
        <property type="entry name" value="BCAT_beta_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.10.10:FF:000004">
        <property type="entry name" value="Branched-chain-amino-acid aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.10:FF:000002">
        <property type="entry name" value="Branched-chain-amino-acid aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005786">
        <property type="entry name" value="B_amino_transII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033939">
        <property type="entry name" value="BCAT_family"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01123">
        <property type="entry name" value="ilvE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009897">
        <property type="entry name" value="PRK13357.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825:SF44">
        <property type="entry name" value="BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825">
        <property type="entry name" value="SUBGROUP IIII AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006468">
        <property type="entry name" value="BCAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 10" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="9">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR006468-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1739828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="403" mass="44344" checksum="E826A28D9572C718" modified="2024-05-29" version="1">MMLQSSLSRCFMSTTRSTITKNKSATTTATHRSISSAQLTISSDSPNNNNNIPQNKQDLQFGKVFSSHMLQIPYKGGSGGWQSPEIVPFHDLKISPAASSLHYGLQCFEGMKAYKSVNDSNDIRLFRPQLNMKRLSNSMDRLCMPGSDFDHEELIECIAKLVRLDQDWIPTEEGYSLYIRPTVISTHPYLGVAAPDEILLYVITCPVGPYYPSGFAPVRLTADTPYVRAWPGGTGAAKVGGNYAGSMKPQTDASNRGYSQILWVFGEEEEITEVGAMNVFFFLEKEDGSKGRELVTPPLTRGDILPGVTRQSIIDLSKSWGEFDVVERSITLPEVRKAASEGRLIEAFGAGTAAVVTPISHIEHKGSDIEIPATGDLTKRFFSDLMGIQYGRIEGPEGWSVKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDN4</accession>
    <name>A0AAD9DDN4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDN4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="73"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="464" mass="52721" checksum="217056AECEA8171A" modified="2024-05-29" version="1">MQRRTHKAVAAAAVVFLVVNAFLLWPEDTSYEYDASEHSRRLDSNGLRAITPRERVLNELFKMGIRPGDPDHRRLLKARLARLEKRNEQALAHREMIRKLRNTKNIWFRRDTTQQAELEQKHAQLRELNLNNHAQKRELNVNTRESDLENLETVSICGRPTMMGTASDLALLQNFEEADTCPGENSNKLLLLQGQDQRLFGRTGNNLIEFLHALQYARDHDVQLGIVSNSWAFEMLLKMWMSVKDDDWEVQFEEAFCVKIFNSQDETETQGYELLFPELTVTEDFTKQLFLYQSERSLVEYIGHQAQYLQTLFKNYNTGVGTTASGEPVRDMCSGIKALFGDNKNAIYSVVHSRSLEEAGKTLLGRLSKFSGCDPEAALHMTPDYVKSILEPLGLLDYPIVLITDGQDFAVIQRLLNDPEIAPKLRLVSEEATWIGGDFTVAVMANAFIGNPASTFSGFIARVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DE98</accession>
    <name>A0AAD9DE98_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DE98"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042070265" evidence="1">
        <location>
            <begin position="16"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="168" mass="18590" checksum="E0CE38C961E212E0" modified="2024-05-29" version="1">MRSLLLATYAALSSAFVPQQVYRSPTSFLAATSKHVMTGDVDMDAKYCADHFGECSLDEMERIRDALHEERITHVFSNTDGINNPHGLQEDIAHKLLESDLTLQMGLLKDKLATEHMQEDSRAAFGMMNPRSATMNLPVMDGMVDEESSEALMICLTIAGLALLPQIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DF91</accession>
    <name>A0AAD9DF91_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005222</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DF91"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="123" mass="13484" checksum="8FC2A44458151681" modified="2024-05-29" version="1">MVAINPASTGRRRSASTVGRIFLRFLISCLFVAFYTGVVKRQSKQPLLARNKTDDNIPANAKSVSKDTAAAAAASPQKDWSHCLDAQPNLNITHADAGPRDKVKNPLWLPAYPHHCQKVTLTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFY8</accession>
    <name>A0AAD9DFY8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Eukaryotic translation initiation factor 3 subunit I</fullName>
            <shortName evidence="7">eIF3i</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_004055</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat STRAP family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the eIF-3 subunit I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFY8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071541">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex, eIF3m"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03008">
        <property type="entry name" value="eIF3i"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027525">
        <property type="entry name" value="eIF3i"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19877">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19877:SF1">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 10" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="6"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="48"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="261"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="304"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1744764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="330" mass="36890" checksum="748A84A1108800B9" modified="2024-05-29" version="1">MRPILLKGHERSITVVKFNFDGDLLFTASKDHIPSVWRNENGERIGTFNGHKGTIWDLDVCRFSKRVVTASADASAKLWDCETGECIKTFVHHGPVRGAAWADGSNMFATISDPFVEHNAQISVYDVPENDDPSSYSDSPRLEIDLPKTSDGNVSMLPTLFGSTSMKLSLLPLIMVQSVYMIRRQGRTDFTAKLYDVVDLKHLKTYKTDRPVNDAVISETKDHILLGGGQEAMSVTTTSGKVGKFETRFFHLVYEEEFGSVKGHFGPINALAINPNGRSYASGAEDGYIRLHYFDKSYLDMKDPVPEVLEEGEEDDDEMEEDRESDSDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG31</accession>
    <name>A0AAD9DG31_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylmalonyl CoA mutase-associated GTPase</fullName>
            <ecNumber evidence="2">3.6.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.-.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DG31"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005129">
        <property type="entry name" value="GTPase_ArgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23408:SF3">
        <property type="entry name" value="METHYLMALONIC ACIDURIA TYPE A PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23408">
        <property type="entry name" value="METHYLMALONYL-COA MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03308">
        <property type="entry name" value="MeaB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="359" mass="39693" checksum="B2F9C658670B288C" modified="2024-05-29" version="1">MVRSVLLQLVRCSAQQHSLNCNHHQRRIGSIFITTSCNRGISSLSEEDDKTVDRLAHDILGKPRSDDGDGYKTSSQTMRQRIALSKSITLVESKSLKHRKMADSLLDRLMKDSSNTNTFRLGICGPPGVGKSSIVEALGLYILGLDKNEQEDAFCQKGVLGGLGAYTYDAASLCEFANYELTIIETVGVGQSEVELAECCDLFLLLLAPGGGDELQGSKKGIVEVADVLVVNKADGELHDVARKTANEYKKAVGLLRKPAGWWGTNKNDHVCSDDRSPATPPVLLCSARTGLGIPELWDLIKTYRQNGKITGYIDEKRRNQRRYWLTKYLREHVLEAAKNDAGTRKRKEEIELDLDNVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG83</accession>
    <name>A0AAD9DG83_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Bestrophin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_005011</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DG83"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044669">
        <property type="entry name" value="YneE/VCCN1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281">
        <property type="entry name" value="UPF0187 PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281:SF19">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION CHANNEL-FORMING PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25539">
        <property type="entry name" value="Bestrophin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1744478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="429" mass="48323" checksum="99EED696F8A03648" modified="2024-05-29" version="1">MKHLHASIGLVALVTSSNNFSGGSFSALAFTPIGTQSKCIKTRRSTSRLQVSSLNSDSKDAQEDKYDTAELMASEMEQARLSNQYARYSHDDWLRHRASDRFFANLFKFDKSPIVKNLLDEAAILAVICVGIILWNELLIEGWTDLNEVHHEAPLADLLPSALTFKLALPTEPFFLCGGPLGLLLVFRNDCSFGRYKDAFHHWEVACSSLGNMILMAASSGTSNVEGVKQLSAASWAVVRTLQHEVSGGFDTTYAEDLKKNMPDEQQVQRLLSARNKLHRSHYDVHRAVDAFSEDISNLDKRTIINTFNNVATACAECERLYMTPIPLLYTRHTLKFLTLWMAFMPFAFYDVFATSWNHTGMIPAICIICFLFFGIEEIAVSLEEPFSILPLNELVEEFQENAQETIEWMEEEHQASTKEAPMGIEIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIB4</accession>
    <name>A0AAD9DIB4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YchJ-like middle NTF2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002508</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIB4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004027">
        <property type="entry name" value="SEC_C_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048469">
        <property type="entry name" value="YchJ-like_M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33747:SF1">
        <property type="entry name" value="ADENYLATE CYCLASE-ASSOCIATED CAP C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33747">
        <property type="entry name" value="UPF0225 PROTEIN SCO1677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02810">
        <property type="entry name" value="SEC-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17775">
        <property type="entry name" value="YchJ_M-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042034657" description="YchJ-like middle NTF2-like domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="YchJ-like middle NTF2-like" evidence="2">
        <location>
            <begin position="108"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="183" mass="20150" checksum="68561A5061393311" modified="2024-05-29" version="1">MHAMSTILFLTLLGFTTGFSIITSRPNAAVGARPTTALAAKGGSKKKKGIARTTKGFGEPPPKLEDVLAKMKTRTPDNANEVDCPCGSGKTHGECCGPFLSGEKKCLTPSDVLRSRYTAFTWRNIKYIMDTTHETCRDYREDRVAWANDLNKGGMFDSFTFVKLDPSKEEDGRMKMRASLSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIC2</accession>
    <name>A0AAD9DIC2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIC2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042249009" evidence="1">
        <location>
            <begin position="19"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="235" mass="26526" checksum="7239252DE54A03CE" modified="2024-05-29" version="1">MMFVRLAILLCLVRASHCFRYSSLSHRLSSNQRRQYGAIEFRSNIQSKSIQRNRHHYIQLDMSDGDDDIISGSSKFSMEEIPLNQIFSKAVVLQRCGDRTGALQEYNHFLQVAETHDVDPSLYAEVHANTAAIYAMQGKGADADSREMRVKAKEAFQEALKYRPSLGSAWVNLALLQLAEGKELGANEQDEVKKVLKDARSCCERALGLDNDDERSRSLANKLIGDIDTMLKQIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJH2</accession>
    <name>A0AAD9DJH2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Receptor ligand binding region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001953</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJH2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34044">
        <property type="entry name" value="NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34044:SF1">
        <property type="entry name" value="NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042256051" description="Receptor ligand binding region domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="409" mass="45285" checksum="52DD486B0F4D448F" modified="2024-05-29" version="1">MMMGEKFLAVLVVAMVTPISHSFSFTLSATGLVTKRYHTSTTHRSSTGSFEKKISFSSALGMATWSNGQAIKEYQDFLSTGRSELQKEDDGPSVIVQSSKPNNVLALTDAIIGLGQGDDIVLNPSDTLPDTLGDRSSYPIYIALPPYELKEFIQNLNDEWKSRAEDFVFFSGGNVCGVVEPVLREFGMCRDSMTQVVVGFSTPAPGTGLGGATKKPEDLSCMIGHDTRGEEKWAGESQSCGKWNAAVASRLDDNGIRCKTVFYREWRRAMWERAVFDCVFNIVGCVREEKTDIADVAMFYELEASDMMWELVNNLRGGLAVTLIYGFEDRLFSIAEMRGKDDICELPVEMFDYSQNVFPGTNLMLKEYLNYAKDKCGLLQGVDVPPVPSQIDELPSKVRMGNLRADGVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DKN9</accession>
    <name>A0AAD9DKN9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_000857</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DKN9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000041">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase ERECTA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052592">
        <property type="entry name" value="LRR-RLK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48054:SF82">
        <property type="entry name" value="LRR RECEPTOR-LIKE SERINE_THREONINE-PROTEIN KINASE FLS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48054">
        <property type="entry name" value="RECEPTOR KINASE-LIKE PROTEIN XA21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="69"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="5">
        <location>
            <begin position="385"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="101"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="29"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="135"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1748918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="532" mass="58100" checksum="9165C1BA924AAAC4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DKU2</accession>
    <name>A0AAD9DKU2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SRPBCC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_001007</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DKU2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1749068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="420" mass="45719" checksum="E036AA5E24E0EBD3" modified="2024-05-29" version="1">MGFGGKKSKKKSKKNKDLVKTKSLPSSFDFEDDVVCRRVSCISLGTGSFTATGVLNVTKSSRNLLGGGDDATCDESPSSSYEDADVNAASRQLSPVNEVVLERVPSIFIRTADLPTMKESANSFMRLSSSDMAESDWVDHIHKPSSLPPLPSMDNDPRESWVALDDGNGNKAPLTEMAMKALVSAGLEASLDQDMWTANGPTSKLLKSGDWDDTVFVSYDKQQPMPAPHARGTKGEMDVLVWSGTFSHKYYGCDLPTIRCEAIVNISPKSLANLLVDSNRVKEYNKMSIGRDDILVLQDDEMCVTKVVCGRSKPPMLGKILQLKTLLHMEELPGGSQNGYVVASRAVSHADDAEAAVDPKVIHSEMLMGLNIIRAVEGEPDRCVLINVNHLMSPMIPMFMAKKLGLSSAVNFINDIRSLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1H072</accession>
    <name>A0A8K1H072_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein bS16c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">rps16</name>
        <name evidence="5" type="ORF">QTG54_017127</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="6"/>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2021" name="Front. Plant Sci." volume="0" first="0" last="0">
            <title>Chloroplast Genomes for Five Skeletonema Species: Comparative and Phylogenetic Analysis.</title>
            <authorList>
                <person name="Liu S."/>
                <person name="Xu Q."/>
                <person name="Liu K."/>
                <person name="Zhao Y."/>
                <person name="Chen N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CNS00100</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Plastid</location>
            <location evidence="4">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bS16 family.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MW679506">
        <property type="protein sequence ID" value="UAM91337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_010200840.1">
        <property type="nucleotide sequence ID" value="NC_058701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1H072"/>
    <dbReference type="GeneID" id="68637958"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00385">
        <property type="entry name" value="Ribosomal_bS16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000307">
        <property type="entry name" value="Ribosomal_bS16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020592">
        <property type="entry name" value="Ribosomal_bS16_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023803">
        <property type="entry name" value="Ribosomal_bS16_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00002">
        <property type="entry name" value="S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12919">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12919:SF20">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS16M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00886">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54565">
        <property type="entry name" value="Ribosomal protein S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00732">
        <property type="entry name" value="RIBOSOMAL_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1732084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UAM91337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="79" mass="9428" checksum="31B03B34AC8808F5" modified="2022-08-03" version="1">MLKLRLKRNGRKRQPSYRLVIMENTTRRDGRPVDEVGYYNPITKESVFNEEKIVKWLSYGVQPTETVFQLLKKSNLIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1LV78</accession>
    <name>A0A8K1LV78_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytochrome c biogenesis protein Ccs1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 11" type="primary">ccs1</name>
        <name evidence="9" type="ORF">QTG54_017170</name>
        <name evidence="10" type="ORF">QTG54_017263</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="11"/>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2021" name="Front. Plant Sci." volume="0" first="0" last="0">
            <title>Chloroplast Genomes for Five Skeletonema Species: Comparative and Phylogenetic Analysis.</title>
            <authorList>
                <person name="Liu S."/>
                <person name="Xu Q."/>
                <person name="Liu K."/>
                <person name="Zhao Y."/>
                <person name="Chen N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CNS00100</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">May interact with CcsA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Plastid</location>
            <location evidence="6">Chloroplast thylakoid membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the Ccs1/CcsB family.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MW679506">
        <property type="protein sequence ID" value="UAM91333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MW679506">
        <property type="protein sequence ID" value="UAM91377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_010200835.1">
        <property type="nucleotide sequence ID" value="NC_058701.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_010200883.1">
        <property type="nucleotide sequence ID" value="NC_058701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1LV78"/>
    <dbReference type="GeneID" id="68637953"/>
    <dbReference type="GeneID" id="68638005"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01392">
        <property type="entry name" value="CytC_Ccs1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023494">
        <property type="entry name" value="Cyt_c_bgen_Ccs1/CcsB/ResB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007816">
        <property type="entry name" value="ResB-like_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31566">
        <property type="entry name" value="CYTOCHROME C BIOGENESIS PROTEIN CCS1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31566:SF0">
        <property type="entry name" value="CYTOCHROME C BIOGENESIS PROTEIN CCS1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05140">
        <property type="entry name" value="ResB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="3 6" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="5 6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0934">Plastid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="2 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="ResB-like" evidence="8">
        <location>
            <begin position="12"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="ResB-like" evidence="8">
        <location>
            <begin position="350"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1732127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1732220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UAM91377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="421" mass="48627" checksum="B18360290F3BDB80" modified="2022-08-03" version="1">MRQNIFKSIADLRFAIFILLVIAAFSVIGTVIEQDQSIETYKLNYPLTNRVFGFLSWDIILKFGLDHVYKTWWFITLILLFGISLLTCTFLQQFPSLKIARRCQFFRTTQQFCRLNISTNLQHLSFPQLLFKIKENNYSIFQQKNIIYCYKGLIGRIAPIIVHFSMIIILMGAIIGSVSGFKAQEIVPKTETFHIQNVLNNGQFTLIPKVSIRINDFWIAYTKQTTITQFYSDLSVLNVDGNEIHRKTIFVNSPAKYNGIDYYQTDWNILGLRVKNKDFSVSQYPFINLPNSQEKIWLTWVSNNPELNDGLTILIDNLQGYCSVYNKVGKFIGNLELNESLNTETPIVLMDILSSTGLQIKADPGILLIYLGFLFLMISTLISYITYSQIWLVQDKKKIFIGGNTTRATFDFELEFLKLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSS2</accession>
    <name>A0AAD8XSS2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016299</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000055">
        <property type="protein sequence ID" value="KAK1732968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSS2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="441" mass="49751" checksum="69B3AD93EE520A49" modified="2024-05-29" version="1">MDFIKKCHPYQWRVYPLLGGFNNAQRKFEPKISGAVHVRPKSAKEIGYTGRITSINTKAKSTTHVYSATELHVSQKKRKLTEDMRVTIQQHCYHHTEKYEDCITCHSTKHDVRPSRLVPVYDLHLKNNKIDKDAESLVLLTPDTTTYRQLATSHLRPNDYVLEIGCSTGECTALLLRRNLLLQSQNLRQIEQHNNVVLGNIVGFDTGAKILKQADNRLRREYNQSATTLATDDDAYSKLIQLHRVDALADPKGAYALATSNNTCPGMVLIDIGGNRQLESVVRMIQWVQTAFKDERPRLILVKSEALENELSTALRSSHTDDNNDSSVPSVTDEGTITNGQNWFNSLESPSIVADKEAGKCLSRQQLLSRYSHPKKVPLVLSPKGIPICRYHNYHPDGCTKFIKSKSTGTVADDVQCQYDHEYCHWCQDAGHIAVNCPSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XT07</accession>
    <name>A0AAD8XT07_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Selenoprotein O</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016241</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000054">
        <property type="protein sequence ID" value="KAK1733103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XT07"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041999174" description="Selenoprotein O" evidence="2">
        <location>
            <begin position="20"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="651" mass="72164" checksum="8D5EDF252C6F5785" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUW2</accession>
    <name>A0AAD8XUW2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000045">
        <property type="protein sequence ID" value="KAK1733786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUW2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="91" mass="10364" checksum="E00FAB405BFDFBC2" modified="2024-05-29" version="1">MKKQQLVVMQLRFIISQLMSGMRKDQRAMKRWIIAANLGCNLSLKQLKNICDEGKMSKEDFAAALRSHLTAVDAMKSPEITAARSLSRRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUW9</accession>
    <name>A0AAD8XUW9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_015165</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUW9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="85"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1734162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="523" mass="58209" checksum="771A0A8C4D2EED3F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV53</accession>
    <name>A0AAD8XV53_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015182</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV53"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="19" mass="2171" checksum="21CD5812B1569B88" modified="2024-05-29" version="1">MHALNPFARKTILAVFHCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVC8</accession>
    <name>A0AAD8XVC8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014807</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000038">
        <property type="protein sequence ID" value="KAK1734559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVC8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="30"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="265" mass="29964" checksum="FC6B20CE530EFBBE" modified="2024-05-29" version="1">MPPKKKTKLTRRPSDDAAAEEVDPAVVNQLDDNVIAIIFSCLGPVDIMRMRRVCKKWRDAAKKTIVDHFCVDSVVNCNAMRVMATALPNLQQLSMCGPGHLHKYSDGEDPDEEMATAFAHFTTHDINIISNFRKLHRLNIDGAFMNGRYPTLFNFPLLEKLRISLCCSFKWELEMLSGFPSLRELDVECNRSLRGNIGSLAVLKNSLEKVKIIDCNNVVGNFMDLADFPQLKLLDLQRTAVTGDIGEISENDFLTWKNISFSQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVJ0</accession>
    <name>A0AAD8XVJ0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014975</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVJ0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="629"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="2">
        <location>
            <begin position="10"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="790" mass="89019" checksum="923F3C92A35D7C4B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XX64</accession>
    <name>A0AAD8XX64_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XX64"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="222" mass="24530" checksum="327728CFA1427029" modified="2024-05-29" version="1">MMYLSNLPTGALAHVSSYLAAPSRALFAVALDHRDVDSSSAIAGDDWEALDFGDIEKDLAAKLSDDDIRGVLLSIDAVNNLKRLRLTNCINISGAGLDPLRGSTIIQHIDLSLVGDHESAKLDPEPPISCAEVLPILDSIIERGEDCSLEHLQFPNEWRKERNTESDFHAFLTRYNDYLSRQAVVCLKCSCNLPGDERTGDGHMLRMSDYQYGTQNFTCMIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXE1</accession>
    <name>A0AAD8XXE1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014256</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXE1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042274001" evidence="1">
        <location>
            <begin position="28"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="306" mass="32770" checksum="249239F232772B1B" modified="2024-05-29" version="1">MATHRPSSLALITAYAAILLPLSLTSGGGVSAFSRPQSHHPNKATIPSCPPPISMPVWSLSCPIPFPTQELSSSSMSILTFVTPVSVSSPKLWAVSLYKTSLTRCSFLGVTNRGEEYNDIPSTASSVTTTSGSAYSVRRRDSMGEAGLLPGGVDGAVGWRVTGEYRRPGSKPLGSTQGVGILQLLSPKQSKLVPILGKMPGWDGGALMKKEECAKIGHEWVAVGSDEEEEQFEVLPHCASYIQIKLKRVTDGGDHDVCIVQVTKNGVWDDVNKTVFWLEEGDQQQQPALDSTAALYSGQLRDEGII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZH5</accession>
    <name>A0AAD8XZH5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZH5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="477" mass="54103" checksum="4875F8357042BEE6" modified="2024-05-29" version="1">MFSSTISHPFYSSTMIAPIDTEMKGVPRRHSKSFEVDRRSPSSVIDEAFWTGEERHESSSNAQNGDIHRAQKTNHCDILTEDDFLAGLDLYWCCSSNDANAGNIIDISGSVPKKSQGCGGYIDYIGTYHQCTANIQNRYALEPCQGCVFRRGIKDVTMTTLYTTKSCITTHSRSKSDSIPSLTTPRRKHSRSNSDATPTLDDTDRDQVMAQNWESPLRTNSTPSSPTRSIRGVQHIDEAAHAEQQAYMYDYFLQEESPIRTGVCSTMKAEIGNYVQDALNSRWRLDWHHVAHKGNSSLLRRHPKACEVWIERGYCRNRNEMVEPKLMWRELTQPGLKEGMLTESTLNPYRASLFALRKIVPVVDGDDWQRMSFDGKKPCNTNAWKPMVKPNCLIAVRSSLGQDYLFEASCPEERDRIIHLWKMATARLVSHAVAGNIDMMMQEFFNEAAIRGGLYASMLTTVMGEPIEDNNEEEQVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZP4</accession>
    <name>A0AAD8XZP4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Kinesin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_012990</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZP4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF75">
        <property type="entry name" value="CENTROMERE-ASSOCIATED PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 3" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="5">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="107"/>
            <end position="114"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1736390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="148" mass="15272" checksum="54EFB7EB07394E06" modified="2024-05-29" version="1">MSSSSIAASEGEEAPSAIRVLRKQRRLILESKSNAAAAAGSVGEESSSSSASAEGTVTIADHQQGGSSFTYDAVFGPESQQIDIFESVKGIVDAVVSGYNGTIVAYGQTSSGKTHTIFGEESALSSSTDNDEATAGLVQRSLKLYLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0P9</accession>
    <name>A0AAD8Y0P9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012327</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0P9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="200"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="417"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="475"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="575" mass="64105" checksum="B6B376CC25D991C9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y100</accession>
    <name>A0AAD8Y100_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="20">Sodium/potassium/calcium exchanger</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">QTG54_011703</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y100"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005262">
        <property type="term" value="F:calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008273">
        <property type="term" value="F:calcium, potassium:sodium antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1420.30:FF:000004">
        <property type="entry name" value="Sodium/potassium/calcium exchanger 2 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1420.30:FF:000009">
        <property type="entry name" value="sodium/potassium/calcium exchanger 5 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004481">
        <property type="entry name" value="K/Na/Ca-exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00367">
        <property type="entry name" value="calcium/sodium antiporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10846">
        <property type="entry name" value="SODIUM/POTASSIUM/CALCIUM EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10846:SF73">
        <property type="entry name" value="SODIUM_CALCIUM EXCHANGER MEMBRANE REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0050">Antiport</keyword>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="15 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="13" id="KW-0915">Sodium</keyword>
    <keyword evidence="16" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="10" id="KW-0769">Symport</keyword>
    <keyword evidence="7 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="192"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="261"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="323"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="762"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="827"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="862"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="897"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="19">
        <location>
            <begin position="558"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="19">
        <location>
            <begin position="594"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="19">
        <location>
            <begin position="637"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="23"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="359"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="426"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="51"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="360"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="380"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="470"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="490"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAK1737417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="925" mass="100952" checksum="8BE1EB9BBE36F0A7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y141</accession>
    <name>A0AAD8Y141_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PPIase FKBP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011763</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y141"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042207100" description="PPIase FKBP-type domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="2">
        <location>
            <begin position="97"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="231" mass="24408" checksum="1F9665E63362D967" modified="2024-05-29" version="1">MKAIASVSLIVVAAVVLLGCASALQQPAATNQFPTRRSILSLPPKAVIAAATGASSATITPSTANAAKPNGLILDKSSESGLKWADAKQGTGQPLKPGMVASIDYSMASTVGRQPQIYTTKDKGVPYRWTLGDGSTIAGIELAILGSSGDDNSIPPMLPGGIRRVIIPANLGYQSILNEKDPKCIEGKDIGPIPPKNNSDGGYQRWYQFYCNPRIPYQPDIVLDIKLYGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1J6</accession>
    <name>A0AAD8Y1J6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1J6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006418">
        <property type="term" value="P:tRNA aminoacylation for protein translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1910">
        <property type="entry name" value="Cysteine-tRNA ligase, C-terminal anti-codon recognition domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="355" mass="40824" checksum="DC32B9A7458812DD" modified="2024-05-29" version="1">MELIDGGVFVHDGMKEWRADGIPYGSFNGGGSGQGNPRSLDSQQYSKSPHSDDVMVGDVVNNELITKLVKERTKFKMMRQYDKSDAVREGLRTKFNVMIDDRLKQWSVGGDFGEEHNAQRELADKFANRGYIKSTSSLSLEDAEEEEYIQFHVDARVQAKKDRNFETADKIRLDLAQRFDVMINDKMKLWSIGGQFEELGGKMGKPRGVYTRRGALGDLTPEDEDTVSKMIADRYHAKKQKNFDVADEIRDDLLSKYNVRIDDRSNEWRVDTEDYAMAGTNSLTEDEVAFIDGKLKERFYFKRERQFEEADEIRDHLQERFGIQVDDRVKEWYVDSLLSGVGVAEVEEDDASIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2G7</accession>
    <name>A0AAD8Y2G7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">FACT complex subunit SSRP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_011584</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SSRP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2G7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035101">
        <property type="term" value="C:FACT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01390">
        <property type="entry name" value="HMG-box_NHP6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21994">
        <property type="entry name" value="HMG-box_SSRP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13230">
        <property type="entry name" value="PH1_SSRP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13231">
        <property type="entry name" value="PH2_SSRP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.30.10:FF:000016">
        <property type="entry name" value="FACT complex subunit SSRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.150:FF:000001">
        <property type="entry name" value="Fact complex subunit ssrp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000098">
        <property type="entry name" value="Fact complex subunit ssrp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.220">
        <property type="entry name" value="Structure-specific recognition protein (SSRP1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013719">
        <property type="entry name" value="RTT106/SPT16-like_middle_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050454">
        <property type="entry name" value="RTT106/SSRP1_HistChap/FACT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048993">
        <property type="entry name" value="SSRP1-like_PH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000969">
        <property type="entry name" value="SSRP1/POB3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035417">
        <property type="entry name" value="SSRP1/POB3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024954">
        <property type="entry name" value="SSRP1_DD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038167">
        <property type="entry name" value="SSRP1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45849">
        <property type="entry name" value="FACT COMPLEX SUBUNIT SSRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45849:SF1">
        <property type="entry name" value="FACT COMPLEX SUBUNIT SSRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21103">
        <property type="entry name" value="PH1_SSRP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17292">
        <property type="entry name" value="POB3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08512">
        <property type="entry name" value="Rttp106-like_middle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03531">
        <property type="entry name" value="SSrecog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00887">
        <property type="entry name" value="SSRCOGNITION"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01287">
        <property type="entry name" value="Rtt106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HMG box" evidence="14">
        <location>
            <begin position="605"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="14">
        <location>
            <begin position="700"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="12">
        <location>
            <begin position="605"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="12">
        <location>
            <begin position="700"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="489"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="649"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="720"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="506"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="528"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="557"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="587"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="659"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="730"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="800"/>
            <end position="816"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1737812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="823" mass="91876" checksum="C2F5534E45A3AB5C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2H6</accession>
    <name>A0AAD8Y2H6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase S74 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011927</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2H6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030392">
        <property type="entry name" value="S74_ICA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13884">
        <property type="entry name" value="Peptidase_S74"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51688">
        <property type="entry name" value="ICA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S74" evidence="2">
        <location>
            <begin position="44"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="126" mass="13714" checksum="28D2B762520A3EF6" modified="2024-05-29" version="1">MDIASKSSKAPKSSKAPKSEGTKSPSTKSSKATTTTPTTAPTVSDIRLKHNIAFIGKSSSGIPTYTFNYREGMNLSNNYVLDTKSTFVGAMAQDLLELAPDAVIMNPEDGYYRVDYSKIDVDFYKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2Y8</accession>
    <name>A0AAD8Y2Y8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010714</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2Y8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="370" mass="41006" checksum="D12B9AFCEE11689D" modified="2024-05-29" version="1">MLTATISSPLPPQQQLSPDDTAYPAAAYSESSSDDNLKQNDHVENDHINHTDEEDKDEITTKALQTNNNEGALHDVDNINEDQPARQSSPINGEASSTTFDKNLPSMTQDDAHKQRTRRANVATIQDDASTAFSPYQPTPSLEAMNSNVPMRYPKKKKSKKRRGKLNENENNNNTKQAKSGQKATAVADINEVDTIATSSTKPQHLSDTLTSISNDDRDGMLQNVNDPILQHYLPKLTFLNDNFYTKVKAYGIGRRNLPQNQIELILRRRAVKKKKDDNHKGDTAAAAATGHKRPPLSTTPTTRRKVFPSTTQQHYDDDSTISSATAASTWTAGSKTQHSRDTTSSPLILLPIATLRNILRSNIRPPNHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3Z5</accession>
    <name>A0AAD8Y3Z5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Rhodanese-related sulfurtransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_010667</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3Z5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022111">
        <property type="entry name" value="Rhodanese_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020936">
        <property type="entry name" value="TrhO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040503">
        <property type="entry name" value="TRHO_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43268:SF7">
        <property type="entry name" value="RHODANESE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43268">
        <property type="entry name" value="THIOSULFATE SULFURTRANSFERASE/RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12368">
        <property type="entry name" value="Rhodanese_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17773">
        <property type="entry name" value="UPF0176_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Rhodanese" evidence="5">
        <location>
            <begin position="280"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="553"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="502"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1738637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="646" mass="73185" checksum="E0140D40C706F0ED" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y447</accession>
    <name>A0AAD8Y447_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009827</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y447"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1739284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="284" mass="33503" checksum="9331F1F8C8C2FC18" modified="2024-05-29" version="1">MLYKLVNKYYPGRMRVVVVYRRYYEWMLSLWNEFNKPFKNGNGDTSDYRPTYQNWPSEGGKRCHTFVSFMKKFMDPEGKRTSDEYRHRAEAEHVHVAEYFRGLWSNHSSEVQVLNLHEMNVPSDDGQDATSRFLQSALTPLAAKTYTRSKDSGFGGRHNPSRNINYDILAVAAHEHGLLANQTIPRAKVAVLLEEHFMKKLNTTDLPLQCPDKELLKRFLQKSIHYEEMLYPGQTDDKEHETTFYEAVKRHKFCNFDFDALVEDEAVRTFFSKEIPRLYRRSKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4H8</accession>
    <name>A0AAD8Y4H8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010094</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4H8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052201">
        <property type="entry name" value="LRR-containing_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24111:SF0">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24111">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="329" mass="37411" checksum="B56BFB3578B220B9" modified="2024-05-29" version="1">MTGKCCVVPNSQGELDLRCQNLTYIGVKRILATLSLRGYTNIQKVDLSGNENIGDIGAVCLQLIPPTVSEVDMSYCNIGAVGLRHICDFMKSNTNIITLSLAGNRFDEKCATCLGEMLRENNTLQVLRAYQYGDGEKRFKYYYNSSFWFEGVVEGLMYNHTLRVLEMVHNTHDMDKVALDAFNHVLCNGGGSAIERLCIGRVRQSFTFQLSLNAVENLGRTGVADYINRITLQLPKAEDSFGKLLSNLFKRCKNLYDMNLTRWLEHPHQHPHAREVQYWMELNTVKARQITEDGEFAGFVDSLVEAKHSDLFDSIFYLVRNNAHQIPKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4S3</accession>
    <name>A0AAD8Y4S3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010436</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4S3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="285"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="355" mass="40510" checksum="35B3114F18934165" modified="2024-05-29" version="1">MIHNHLSYEDADNNSVDSNYDIEIPTITTTGSVDALVTSATTTSLDSIKYDAATIKAEFKTYQTILPHPDKLLQEQHSFTYLRNKIEESEIDMPRFLKYKFEGGIKPHIALCCLLLGEYEAELKKQKEHEKNNKRKKPKYDNHPWGIYPFLVKILSFGYLHNQLNNPADYIRDQFFRVAHVIPTHVVPSDVLRKKIKNKGLPVPNYFLDPDDPRQFPPHIALLVMLQDGEMESRKLDSFLNRLVFSSFALISLLLRIVLEVIGGAGAIWGGAEVVKLRNADNAELWRWLSIGVGVLCFARFVTLNVPYKEDEGDILGPAGPWSLRLSLRLRAVCDHPFHYFVRALPPSTPKKKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y554</accession>
    <name>A0AAD8Y554_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Eukaryotic rRNA processing protein EBP2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_010307</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the EBP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y554"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008610">
        <property type="entry name" value="Ebp2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13028">
        <property type="entry name" value="RRNA PROCESSING PROTEIN EBNA1-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13028:SF0">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN EBP2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05890">
        <property type="entry name" value="Ebp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="445"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="485"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="512"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="594"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="618"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="705"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="12">
        <location>
            <begin position="441"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="345"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="80"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="137"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="250"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1738991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="726" mass="79649" checksum="3DB54D45851D5B21" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5K4</accession>
    <name>A0AAD8Y5K4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_009972</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03223">
        <property type="entry name" value="ABCD_peroxisomal_ALDP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050835">
        <property type="entry name" value="ABC_transporter_sub-D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384">
        <property type="entry name" value="ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384:SF59">
        <property type="entry name" value="LYSOSOMAL COBALAMIN TRANSPORTER ABCD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06472">
        <property type="entry name" value="ABC_membrane_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="394"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="435"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="525"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="552"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1255"/>
            <end position="1276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1296"/>
            <end position="1317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1383"/>
            <end position="1407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1413"/>
            <end position="1436"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="399"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="769"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="1260"/>
            <end position="1556"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1630"/>
            <end position="1887"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="342"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="716"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1203"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1576"/>
            <end position="1602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="716"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1576"/>
            <end position="1587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1739429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1888" mass="213042" checksum="1FF35DAFC53B77A4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5W1</accession>
    <name>A0AAD8Y5W1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5W1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="107" mass="11823" checksum="6988865E47C32029" modified="2024-05-29" version="1">MTSGYSNAAGWLQQISGVDPQANYADEDAKDPILRDLRDMKDAETKDDNLPLPRRSPRISGRNGAQYGVSYMQQQPKPKFVAHKVPTRAKKGKAKVVSNRLGGEHMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6W0</accession>
    <name>A0AAD8Y6W0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Exonuclease 1</fullName>
            <ecNumber evidence="19">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">QTG54_009069</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="19"/>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6W0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035312">
        <property type="term" value="F:5'-3' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09908">
        <property type="entry name" value="H3TH_EXO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09857">
        <property type="entry name" value="PIN_EXO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000011">
        <property type="entry name" value="exonuclease 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1010:FF:000002">
        <property type="entry name" value="Exonuclease 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037315">
        <property type="entry name" value="EXO1_H3TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044752">
        <property type="entry name" value="PIN-like_EXO1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF65">
        <property type="entry name" value="DNA DAMAGE-INDUCIBLE PROTEIN DIN7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00485">
        <property type="entry name" value="XPGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="9 19" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="8 19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG N-terminal" evidence="18">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="XPG-I" evidence="17">
        <location>
            <begin position="153"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="350"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="435"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="510"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="608"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="639"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="383"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="535"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="608"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK1740119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="811" mass="92012" checksum="FE2E20B46D7B7FD5" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y796</accession>
    <name>A0AAD8Y796_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008155</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y796"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="16" mass="1826" checksum="A8ED9247BA00D700" modified="2024-05-29" version="1">MRISRKCCSASMPSIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7B3</accession>
    <name>A0AAD8Y7B3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/beta hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_008991</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7B3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF3">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="3">
        <location>
            <begin position="63"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1740041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="340" mass="37371" checksum="15DFEA1173EEB2E0" modified="2024-05-29" version="1">MSLLAPRITAAASKQQRCVSTAGLSLYDRYHRSISSTSTPKLAYEIITDGKVSSSPHDIINQDKQTIVFLHGLLGNAKNLRTPAKKLTRQLPHLSALLLDVRGHGGSSGSQQHVQPHNFHSCVSDIFHTLTPLGLVGENSPTAICGHSLGGRIALQYTHTLQHQDHDIQTPQQTWILDSVPGKPDPSVHHVLKAISSIPLPIACKSSLTDTLMSEYKMNKAIAMWIASNLKGKNGEHDWVFDLDIANELVDNFADQDFDTMIHEITSGSSDGALDSTIQLVMAGRNKEWKEDVVSSLRSIPTFGHSFHMHKLENAGHWVHVDAVNELTQLMVDGLSNTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8R8</accession>
    <name>A0AAD8Y8R8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sel1-like repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8R8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051961">
        <property type="entry name" value="Fungal_Metabolite_Diox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37563">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G03330)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37563:SF2">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G03330)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="417" mass="46248" checksum="A506598DC8D81FBB" modified="2024-05-29" version="1">MVNEVKNMPAANSIPTQLKRRQPQQRRRGPPGANMMPQDEPWRLSAYGRYHCLENHLGDEDIRVLEQIEQQILPLVQSFFREGDGDESLESSNTTTKTTTSSTSTIMDGIYRSELQLMTAVPGSGNQSWHKDNRARGLSIIIPLVDFTPENGGTQLLLGSHNNNWPLFANGGARVIRAPTGSVVAYDSRTVHRGLGNETSEGRPALIFCYDKVETPPPGCGTLGSVGTSYQGRLVDILTGARNVLSPKRPLPKTDAEVDRMVKRRVEVNDPVALREFGTRCHFEGDYGSAIEYWTRAARLGEAGAHYQLSFAYNLGDDVEKDMKKAIYHAEQAAIGGHYIARHNLGYEEYDDGKVERAAKHWIIAASLGFDDSLESLKDCYKEGCIQKEDFAAALRAHKAAVDATKSPQREEAEAKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y915</accession>
    <name>A0AAD8Y915_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007737</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y915"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38909">
        <property type="entry name" value="G PROTEIN GAMMA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38909:SF1">
        <property type="entry name" value="G PROTEIN GAMMA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="89"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="166" mass="17197" checksum="A61AC10FE5F6CE53" modified="2024-05-29" version="1">MVGKSRREGGGGGGSVSGGSVKSRGGIGASGSGSVVSKQRDDCGATVTSRDYSVGRSSHHSSRQHISASARKAAVRSLRSKVTVVAPPGKLGIILANRTDSRGTVVSGVRTASVLATQVSPGDRIIAIDDEDVSQMNVKEITTIMARKSEFERVLTLLAAPKMQYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y948</accession>
    <name>A0AAD8Y948_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007674</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y948"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="316"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="90"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="455" mass="48091" checksum="4ED635C081011E51" modified="2024-05-29" version="1">MASSSTNNNTTTTTSCQIVLTLAHLLQQHSLSYDSEKNSLLHTSVRCASHLANNTTGGGEVHIVLTGSPRPTFAETNAWLLEGSSSAAAAGNNGVSNSSSGGADNNDIAMTETDDTNDRPAHLKGSYSIADNVHHSSSNIYNNQEEEERMMQDDENTTKSELQEYITEFTDSKDGGNGVSTAAVSNSKRGTTGGGGHNTSFIRRNTTGVTTTTNNNNADDSTNTTNRRRSTIDAAESSSSSSVTNNTGPMVGQAVVNAISQSSGVGLQSSRSKLLQGTIDRPLWSQNRWTDGECLFSELVELCGMERFEMVGGAAHKKRLQQQQQQQGGPDDAAGGAGAPSLAVVASPPATAATNMSANLITVPATTLREPNAGVSQTTMDEIARGVLRTVKRKKSPPASKVYIVLPGVNQGVSEEQRGVVVTSLKQAWEKLEQYNHMIGQPNLISGADLEFVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y958</accession>
    <name>A0AAD8Y958_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rer1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_007740</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RER1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y958"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006621">
        <property type="term" value="P:protein retention in ER lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004932">
        <property type="entry name" value="Rer1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10743">
        <property type="entry name" value="PROTEIN RER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10743:SF0">
        <property type="entry name" value="PROTEIN RER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03248">
        <property type="entry name" value="Rer1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1741262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="224" mass="24996" checksum="28C7AC89C2CED3AC" modified="2024-05-29" version="1">MMEGSDTEAPSSIETQVANFRRAIQYWLDKSTIHIIPRWTLFVCLLAIVFLRIYLIQGYFIVAYGLGIFLLNNFIAFLSPLEDPTDVGGQRDDGLSLPSTAKEGKEYRPFARRLPEFKFWLACARGAATSLLMTFFSVFDVPVFWPILLMYFGVLFFMTMKRQIAHMYKHKYVPISFGKLKYKDAGKEKGEFGGGMAGSIGTTAQNGGGPAPGMMGGGGAVRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBK4</accession>
    <name>A0AAD8YBK4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Tryptophan/tyrosine permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_006072</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBK4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003333">
        <property type="term" value="P:amino acid transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018227">
        <property type="entry name" value="Amino_acid_transport_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32195">
        <property type="entry name" value="OS07G0662800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32195:SF26">
        <property type="entry name" value="TRYPTOPHAN OR TYROSINE TRANSPORTER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03222">
        <property type="entry name" value="Trp_Tyr_perm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="220"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="321"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="391"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="57"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1743451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="529" mass="54796" checksum="BA8BF7DF52505DF1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBN2</accession>
    <name>A0AAD8YBN2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NAD(P)-dependent epimerase/dehydratase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_005894</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBN2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050177">
        <property type="entry name" value="Lipid_A_modif_metabolic_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245">
        <property type="entry name" value="BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245:SF13">
        <property type="entry name" value="UDP-D-APIOSE_UDP-D-XYLOSE SYNTHASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="239"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1743273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="577" mass="63371" checksum="EB993DE49F3E4E65" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YC08</accession>
    <name>A0AAD8YC08_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_006362</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YC08"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="211"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1742765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="221" mass="24590" checksum="B80E1441B79CA889" modified="2024-05-29" version="1">MKSLHLTGNDISADGSCSIIAIADCLATNPPLQELFLAGNKLNDDDAEFIAEGLRTNTNLKKIDLRDNAIGRLGCKALFKAIFNDENLNSVSSSNHTCDIIVTYYKIPCINTELFGGKSGVLLEKKFAMIAPPNDPDVNVHLFSEVPPELIHKVLKLAQKYPEKNVWKYMRHLLQGDELLESGAAHVEESSKKRNFLEKSSQWKSLKGSRQKQSSSFRSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCM1</accession>
    <name>A0AAD8YCM1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">W2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006443</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCM1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005851">
        <property type="term" value="C:eukaryotic translation initiation factor 2B complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11559">
        <property type="entry name" value="W2_eIF4G1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051956">
        <property type="entry name" value="eIF2B_epsilon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45887">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45887:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00515">
        <property type="entry name" value="eIF5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="2">
        <location>
            <begin position="701"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="683"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="181"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="448"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="482"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="574"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="606"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="623"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="689"/>
            <end position="710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="899" mass="96591" checksum="30B37E8FB7C47815" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCP3</accession>
    <name>A0AAD8YCP3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCP3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="223" mass="25583" checksum="7FF2BE39788A6789" modified="2024-05-29" version="1">MSPSSAGSSSRTSRSKLYERYDVEVPNVSSSNANNNLKKWRGGWFKSDRDEATERQQQQLPPDQWTNIEMIRYIFNNSTFKSKLIAILVIMILSSIIRSTLSFHNNTGRSNNNDLETKRGPVMTKYGLRPEKMDPDSHKRSNPFAAPGHQSFMEGVLEVKRVKKRENPPPPPPVQNQQQQQQQKQESLHLETNPSQTQGKRLPQQTRKQAPEKRAKGRKMPSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD22</accession>
    <name>A0AAD8YD22_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005509</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD22"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1743912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="183" mass="21391" checksum="A7E62AEF9C5E498C" modified="2024-05-29" version="1">MTTKQKVTAPTKTMSWEDFYSKTDNANKLMDRVWYCLACTDKSVAQQKSFWEHWYWKDNASENKLNGKKEGCNHTNTKDVKGKEVDYPIWPLAFTESSMKMCPAIDLGYDSRKEFRVDYCNVMGTKMYFIFVLDPNISEEDIQKNFDALETENGISRDWFHKVQWESDYVLGSAGEPDINPNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YE84</accession>
    <name>A0AAD8YE84_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Inositol oxygenase</fullName>
            <ecNumber evidence="4 13">1.13.99.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 13">Myo-inositol oxygenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_004182</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11 13">
            <text>myo-inositol + O2 = D-glucuronate + H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23696"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:58720"/>
            <dbReference type="EC" id="1.13.99.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12 13">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="12 13">Binds 2 iron ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Polyol metabolism; myo-inositol degradation into D-glucuronate; D-glucuronate from myo-inositol: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the myo-inositol oxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.99.1" evidence="4 13"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YE84"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050113">
        <property type="term" value="F:inositol oxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019310">
        <property type="term" value="P:inositol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007828">
        <property type="entry name" value="Inositol_oxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12588:SF0">
        <property type="entry name" value="INOSITOL OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12588">
        <property type="entry name" value="MYOINOSITOL OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05153">
        <property type="entry name" value="MIOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 12 13" id="KW-0408">Iron</keyword>
    <keyword evidence="7 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 13 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="12">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR607828-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU367039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1744891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="340" mass="38439" checksum="28C39D6F8A1BE13F" modified="2024-05-29" version="1">MTGGSVTILDQVDDSYSDVDGWTTFVPLHISDEIDHDDSPLQQSSSRSLWVLRSCHGTFLTADSVSKCFSCTKLPSFWQANGSNLSLACTSDTPPRRHHYLQCWKLQTHEYVQSMRSRFLNFSLGNATLFEALDTSGSSMVSSPSLRTLSFLMAEAAREEGLPDWVQLVALFHELGETVKKLDPNNTGKMADSIYDWTISTRSRVVGCAIPNCATFSEFRHLNTDVLDARYSTDTGVYEANCGLDNVLLLWSGPEYMYHLLRHNQTALPLEALAMVRYYLLGDWHEHHEHTSITNEYDEDMLPWVSDFDRLRRKTRMECLDCVDLSAEQCDTFGIATTAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEJ7</accession>
    <name>A0AAD8YEJ7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEJ7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097546">
        <property type="term" value="C:ciliary base"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097730">
        <property type="term" value="C:non-motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019894">
        <property type="term" value="F:kinesin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042073">
        <property type="term" value="P:intraciliary transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905515">
        <property type="term" value="P:non-motile cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44117">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 88 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44117:SF1">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 88 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="118"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="157"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="395"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="585" mass="66448" checksum="7BE34A18B6179EDB" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEQ4</accession>
    <name>A0AAD8YEQ4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transitional endoplasmic reticulum ATPase</fullName>
            <ecNumber evidence="7">3.6.4.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_005016</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.6" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEQ4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034098">
        <property type="term" value="C:VCP-NPL4-UFD1 AAA ATPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097352">
        <property type="term" value="P:autophagosome maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051228">
        <property type="term" value="P:mitotic spindle disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030970">
        <property type="term" value="P:retrograde protein transport, ER to cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.330.10:FF:000001">
        <property type="entry name" value="Cell division control 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000079">
        <property type="entry name" value="Cell division cycle protein 48 homologue"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.40.20:FF:000003">
        <property type="entry name" value="Transitional endoplasmic reticulum ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000012">
        <property type="entry name" value="Transitional endoplasmic reticulum ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000048">
        <property type="entry name" value="Transitional endoplasmic reticulum ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.20.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004201">
        <property type="entry name" value="Cdc48_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029067">
        <property type="entry name" value="CDC48_domain_2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003338">
        <property type="entry name" value="CDC4_N-term_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF171">
        <property type="entry name" value="NUCLEAR VALOSIN-CONTAINING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02933">
        <property type="entry name" value="CDC48_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02359">
        <property type="entry name" value="CDC48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01072">
        <property type="entry name" value="CDC48_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01073">
        <property type="entry name" value="CDC48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="ADC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54585">
        <property type="entry name" value="Cdc48 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CDC48 N-terminal subdomain" evidence="6">
        <location>
            <begin position="73"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="CDC48" evidence="5">
        <location>
            <begin position="175"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="288"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="565"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="834"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="844"/>
            <end position="855"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1744483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="855" mass="95313" checksum="CEBAD3BFAC3986C7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEY3</accession>
    <name>A0AAD8YEY3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005317</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEY3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1743720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="362" mass="40818" checksum="B6A2C6933D3620A8" modified="2024-05-29" version="1">MTSTYAVPVAVPLPCDDDINLAATAPPARFGGLQKGRSSYKLPSSRINGAFAPNFPLRIWVVDNSGSMQHTDGHRFVETKRQQDVKIVSCSRWDEIKGCVEYHAQISAALEAPTTFRMLNDPHVGPNSQQFGIAETSLDPNVIQEEVSRAVAIMNQSQPGGVTPLIRHLREIRQSVVEMAPELYANGTRVAIILATDGLPTDEHGYNNSAVQQEFVQALRGLESLPVWVVIRLCTDEDPLDDQLELSLEVLDDFLKKLRRYMNTTPGSIMHSHCIGYERWATTIRPLTHQEVKDFCGLLLIDRQPYDQLPDPAADWKEFSRTIKGLLAKQPGQWNPKKKKVTPWIDMKKLDKIYGDSKWKFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YF20</accession>
    <name>A0AAD8YF20_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YF20"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="397" mass="44303" checksum="6544E3231AB11D3F" modified="2024-05-29" version="1" fragment="single">SSSTTHEQRYVSSTATTAVAEAAAAADATSSRPIPRDMARTSLLSSSHHPSQRPPMGPPSPHTRGPVPYSVQSSVNPALVSPSLLHSPASAQSSAYPRTVVSPHSPASPQANAPVVTSKPPRPYTEYTMFYQLEREFVLRKVLCSEEEQKKEKDAENGEVALFRNDPLMPERYRDLPLRADWYISGKSKKPSKRKHRKSHGKIGFLELTRMIAARWAKVDDETKKYCKMMAAMELVKYKEDMESYNAYTERLSAIGEIPEDMKARELKKRIANERKKNKNAASSPGVTKETHVAPKRTAPSRKAKVAKRSTSVEDDMELFISSLVDEKPKTVVSPDRPLKRQRVIKSEQPQAADEDQLGGIKMAFSGIDENEIAREFPLPFLGLLLCQCLLQVLLVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFA2</accession>
    <name>A0AAD8YFA2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004918</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFA2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="145" mass="16218" checksum="97B1E886A2D0D2FE" modified="2024-05-29" version="1">MDYSLYDYIEQIGLLHQDEQVDDACIEQHSDAAAAAKTNIVERQRRQANTHIIFLSHRSVGNGLDKLVHAILSANERQMEKESRHRINNDSGSLQQANGSMYLAKKIHLRCTNIKRGITSLASLLSRSTSTEVLDLSQNELGSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFS7</accession>
    <name>A0AAD8YFS7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004374</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFS7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1745083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="350" mass="39641" checksum="6E669194B5EB183F" modified="2024-05-29" version="1">MSVAITCAKEAQELKLQFERIDLALKQCQSDALENSPSMIDSLQTLYNLLIEMKPMAIQSDISRSRVEIRLRDVAKDLICMNRVVMSIDDEIEGVVRETLYDDFGWYHEASDSVAQIRIECDGNNERIEACDECNAPCHDSERWIDKCLDLCGYGVSLEAAVDCLRRTVHYSSSSSNNNDNNNDMPLKQKGETFGIASSVTSLRTIRRYLLHVPSLYQEGHVDCCPITFQLKFLTKEDTSILPQTETIWNCCILPLEYHCKRVHEEPHELESEPILGDSLTDLTSVLPTLVSSVCHAMDLTLPWWAAPKTMHTMLIQAAWKMLLAGELVEIKHLLSVSLLPATFNCLRDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFX5</accession>
    <name>A0AAD8YFX5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFX5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="328"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="830"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="863"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1032"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="610"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="330"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="834"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="907"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="940"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1032"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1050"/>
            <end position="1073"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1073" mass="121184" checksum="DB10FA797816A93B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGD5</accession>
    <name>A0AAD8YGD5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGD5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="371" mass="42110" checksum="FF07640E0B44EE9F" modified="2024-05-29" version="1">MARLLHTAIATISFLLTYVIGQKAFSFAFLTHHHQHRSRSTHHPTLLASSPPLVHDDNETPTNTTSFTSPKFRVYIEDTDAYQVMYNSNYARQYERALIHAPRDDDAKRKQWVMTAITNQKFRSSPTLGSEYVVTGQLVERSGADNTEVWQMEMVSLPTNDIDGNADEVVIVYNAAMVTLSSTPHVLSSPDEDVSTSSSELYHTQSFPCYPDEFDMHLQTTTSTDTRTQQYAYHIPIRSVTNFFERHRTTYLGGPDKLRKLQQEDGILFVITAMDDGEICSLDAIDGANHLGRDVIVETKFVAKRRGMVVECYHRLLMDIDIDDDDHDSPSKSRKLLAKATMTMMALNKDTYRPTSNLPQWLMDLISSVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHA9</accession>
    <name>A0AAD8YHA9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA-uridine aminocarboxypropyltransferase</fullName>
            <ecNumber evidence="1">2.5.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_002895</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a uridine in tRNA + S-adenosyl-L-methionine = a 3-[(3S)-3-amino-3-carboxypropyl]uridine in tRNA + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:62432"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:16092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:82930"/>
            <dbReference type="EC" id="2.5.1.25"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.25" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHA9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016432">
        <property type="term" value="F:tRNA-uridine aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005636">
        <property type="entry name" value="DTW"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03942">
        <property type="entry name" value="DTW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DTW" evidence="6">
        <location>
            <begin position="43"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1746288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="205" mass="22773" checksum="23889614F4FA311F" modified="2024-05-29" version="1">MTIEQVDEAINARKLASTTLNEQLIAIEEDNKQNMTAAEIGRQKHRSLLPLGLQKTSILMKGLLEHEQIMNELLCRKNVTPVVLWPDKKSKRASTTISDLKRIIADNSSGNQNEGSNHGGIVIISIEGTWNTARKMVNKLPPHVLRLDLSDEIRLNFTTPEMNEGIFIDNSVTTAGVTSQSTSAPSLLSPLRRQGKELSKIMSRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHE1</accession>
    <name>A0AAD8YHE1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002754</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHE1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="297" mass="32009" checksum="B839B113B81B884D" modified="2024-05-29" version="1">MADGVTGPLGINPLHFSAGCFLLLFLFVAYLLLPRGVRVQYFGAYPKRYAWSARSRGRRTGGNKRGGMSVSSVGGEGSIYGSSSVAGGSVIQNNQLHQQQQQQQQRQGMMSNNNNQNTPSGTASTISASAAASDDIVVSAAMQQLRDPGVLIVAHGSRGKPKTVRLMLTETTITWRTEMRRKSPSNPNSKELKLGKLHSVLLSHIMYVDIGKQTTALRRVENASVSEALCFSLLTKEGSLDLEANSPRERDALVQCFSLVLDEVHAQNWRDIYRGPSSDMPSSFDDGDGGMGGAGMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHG4</accession>
    <name>A0AAD8YHG4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Tyrosyl-DNA phosphodiesterase 2</fullName>
            <ecNumber evidence="6">3.1.4.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_002985</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0696 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHG4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09080">
        <property type="entry name" value="TDP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.760.10">
        <property type="entry name" value="RNA Cap, Translation Initiation Factor Eif4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015034">
        <property type="entry name" value="Bles03"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014905">
        <property type="entry name" value="HIRAN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023398">
        <property type="entry name" value="TIF_eIF4e-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31977">
        <property type="entry name" value="UPF0696 PROTEIN C11ORF68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31977:SF1">
        <property type="entry name" value="UPF0696 PROTEIN C11ORF68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08939">
        <property type="entry name" value="Bles03"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08797">
        <property type="entry name" value="HIRAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00910">
        <property type="entry name" value="HIRAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55418">
        <property type="entry name" value="eIF4e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIRAN" evidence="5">
        <location>
            <begin position="684"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1746378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="798" mass="88629" checksum="876DF4F9019AA713" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHX0</accession>
    <name>A0AAD8YHX0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Malonyl-CoA decarboxylase</fullName>
            <ecNumber evidence="3">4.1.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.9" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHX0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050080">
        <property type="term" value="F:malonyl-CoA decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001294">
        <property type="term" value="P:malonyl-CoA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.150">
        <property type="entry name" value="Malonyl-CoA decarboxylase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.90">
        <property type="entry name" value="Malonyl-CoA decarboxylase, oligemerization domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038917">
        <property type="entry name" value="Malonyl_CoA_deC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007956">
        <property type="entry name" value="Malonyl_CoA_deC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042303">
        <property type="entry name" value="Malonyl_CoA_deC_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035372">
        <property type="entry name" value="MCD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038351">
        <property type="entry name" value="MCD_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28641">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28641:SF1">
        <property type="entry name" value="MALONYL-COA DECARBOXYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05292">
        <property type="entry name" value="MCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17408">
        <property type="entry name" value="MCD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Malonyl-CoA decarboxylase N-terminal" evidence="2">
        <location>
            <begin position="119"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="Malonyl-CoA decarboxylase C-terminal" evidence="1">
        <location>
            <begin position="240"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="539" mass="61522" checksum="55735B45895A42BE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YID7</accession>
    <name>A0AAD8YID7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_003249</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YID7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="308" mass="34919" checksum="F83BF3902374E09F" modified="2024-05-29" version="1">MRMAAVGSSRRIPSYYCPTTWQILLLLALYSALSSVFLMERTVGGEETNKNHGNDGQAPTQGAFESALNEVTQLITDERTKSNINAEITRRDFNLTMWDKKTTGGLKDLDRIKLAAIYRNATSVFEWGLGESSFIAAEVGVPRYTGIDSDPTWIKAARDSSPDHFRFHLGDIGPTGHWGRPDRSRLKKSYLNYQFEPLVSEKAFDVYYVDGRMRPACALVAFLHASTRGDTEEEKSPIVIIHDYYHDKMSQNCSECRKFRWQYPYHRIEEVADLVDHSGAMLAVFKRKKGVTDGEIKALWQEMGLGDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIH9</accession>
    <name>A0AAD8YIH9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">6-phosphogluconolactonase</fullName>
            <shortName evidence="2">6PGL</shortName>
            <ecNumber evidence="2">3.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_002530</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12556"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="3.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.31" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIH9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01400">
        <property type="entry name" value="6PGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005900">
        <property type="entry name" value="6-phosphogluconolactonase_DevB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039104">
        <property type="entry name" value="6PGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01198">
        <property type="entry name" value="pgl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11054">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11054:SF22">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine/galactosamine-6-phosphate isomerase" evidence="3">
        <location>
            <begin position="19"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU365095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1747186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="285" mass="30943" checksum="B215240EDD5FADB3" modified="2024-05-29" version="1">MENDSNNIHQAKLVIAPAKSAISTILSNLIIQSCHRALQQSTIFTIAISGGSLPTFLQELPDAFSKANIDPQWDKWHVLLADERCVPSSHEDSNLGAIRTHFTNGVGIPPSQIYGIDETLLGSSDDVAASYQENVVKYLLDKKKSTDDDGKIDCALLGFGPDGHTCSLFPNHKLLSEQNRLVASIADSPKPPPSRITLTLPFLNKYCRQIIFCGAGESKRQIIQAVFTDVEKANNNAVKHDDSVLVGAKVSLVVLCNPAPYPCGMVHGYGDDDSLIWLVDEDACS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YII9</accession>
    <name>A0AAD8YII9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_002545</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YII9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF147">
        <property type="entry name" value="SEL1L ADAPTOR SUBUNIT OF ERAD E3 UBIQUITIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="7">
        <location>
            <begin position="18"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="278"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1747201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="435" mass="48758" checksum="1172AA3233295B63" modified="2024-05-29" version="1">MSANEDLEEASNNMMMYCAACGIAGADDIKLKKCTACKSVRYCGVKCQKEHRPKHKKECKNRAAELRDEILFKQPECGDLGDCPICCIPLSIDAQKSILMACCCKMVCAGCNIANQKREVQESMENKCPFCRHPAPYNEKEVKINLMRRIEVNDPAAMRQMGQFCYYEGDHRGAFEYFSKAAELGNAGAHYLLSSLYDKGEGVKKDEKKEVFHLEQAAIEVDDTKLKKCTACKSVRYCSVICQKEHRPKHKSECKKRSAELRDEILFRQPESSGLGDCPICCIPLPINAQGSTLMACCSKTICNGCAHANTIHQLEENLEESCPFCRHPAPDSDDETKKDLMRRIEVNDPSAMRHMGTCCHQEEDYGGAFEYYTKAAESELGDATAHYLLSCMYHAGKGVRRDEKKKVYHLEEAAIGGNPFARNNLALSINTLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJH8</accession>
    <name>A0AAD8YJH8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF1336 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002918</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJH8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009769">
        <property type="entry name" value="EDR2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31558">
        <property type="entry name" value="CW14 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31558:SF35">
        <property type="entry name" value="PROTEIN ENHANCED DISEASE RESISTANCE 2 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07059">
        <property type="entry name" value="EDR2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein ENHANCED DISEASE RESISTANCE 2 C-terminal" evidence="1">
        <location>
            <begin position="10"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="121" mass="13763" checksum="C9685BB88C24FD66" modified="2024-05-29" version="1">MVPSSRVGPDFKGRFKCMGQIEDIESTSIPKFIHGYNGKPALVTKSGTFTRHENYIEFTINVNYWAFLARKGLHSLMPYFQDFIFNVGFTIEARHDEEMPEVLLGGCRIMNLDPDKAAVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJM4</accession>
    <name>A0AAD8YJM4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sel1-like repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_002093</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJM4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="8">
        <location>
            <begin position="12"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="77"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="149"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1746749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="375" mass="41884" checksum="86A0BDB0B4337C67" modified="2024-05-29" version="1">MSADEGEEASCCASCGIAEVDEIKLKECSACDLVRYCSDACQREHNSQHQQECKKRAAELRDEILFKQPESTNIGDCPICMVPLPLDSTKSIMWSCCSKIICNGCAHANGLRERKEKLGHSCPFCRKPVPSTKKQCDKQIMKRIAANDPVAMHQKGMQQYRKGDYRRAFEYYTRAAELGDAAAQYGLGRMYEFGKGVEKDEGKEYTIWKRLQLGGIPVLGVHLDGKNGAKLGDDDSMEMLMIAFKSGLVSKDDLASALRAHQAAEMQPRVRQGTHSNHYNLLPLLLVSIMYYEGQGVEKDKKKDVYHLEQAAIGGHPNARHNLVVCYRKGFVSKEDFAEALRARQVAVNFMKSPQRDKAKVALSKLKAAKAARQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YK61</accession>
    <name>A0AAD8YK61_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YK61"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041922295" evidence="1">
        <location>
            <begin position="26"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="196" mass="20511" checksum="29A8D75A55099FA8" modified="2024-05-29" version="1">MTAMALPTLFLALFLAVNPLSEVLAFAPPASFAVRSYSSTSIAASPLRSDDNDAFTMMSSSSAMDNNRKAFLQSMLTASAAVVTSTLQPITAANAATSSQAAAFLGTYSDPINHPGGTRTITLIDGASNGDYQLAQINGGGGRGEPTEYILPAVIFGDRAIVIDFSPKGGPRDFAGVLESDGSIRFIRDGNRWPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKV8</accession>
    <name>A0AAD8YKV8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Eukaryotic translation initiation factor 4E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_001955</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the eukaryotic initiation factor 4E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKV8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016281">
        <property type="term" value="C:eukaryotic translation initiation factor 4F complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000340">
        <property type="term" value="F:RNA 7-methylguanosine cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.760.10">
        <property type="entry name" value="RNA Cap, Translation Initiation Factor Eif4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023398">
        <property type="entry name" value="TIF_eIF4e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001040">
        <property type="entry name" value="TIF_eIF_4E"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960:SF8">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01652">
        <property type="entry name" value="IF4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55418">
        <property type="entry name" value="eIF4e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1747992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="192" mass="21730" checksum="CF5AC71740F53414" modified="2024-05-29" version="1">MTDEAAPTTLHNKWTLWYDNPRLAPPGTDWHEQLKNLGTFQTPEEFWSIFNNIQPSSQLALNSNYHLFKAGVQPMWEDPANKEGGKFVLTIPKKDSKTGRTNEWWLYTVLAVIGETMDASGDEVCGCVVSIRKAQDRIALWMKSCDRKACTEIGARWKKCLEVSNKTGLKYQAHKDAAASGSSFKNEIKFEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKZ6</accession>
    <name>A0AAD8YKZ6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">START domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000252</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKZ6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042167030" description="START domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="357" mass="40236" checksum="D7C260750E876FB4" modified="2024-05-29" version="1">MKLPLIISAALLARAAAVQKVCARQSRYNPSFIPRRHHQVIAAFGNPKYYSNKFIRADKDGVELKVPKFDVFFDELQKVSPLVKQAIHEENPGGIAAIDDAADVYKWKNMERHPNRLISQVDKIDNFQDHGVPLIRVRSSLRGPSKQRGIYFSELISTTDLRHKWDATNNIVETIYNAADLDDIKRFQGDKYGEPVMFGVGYVKTKQSVVSPREQMTLCGVQNFPSGASTVWGVELEEDQNHLFPKDQTKRMPRSTSHLFAMTMIPTGEDTFDVEYVLQLDVGGLPGWLLGPVVTETVKKMFRFAEKYCESGFEEGGELAKRLAAFPADEEESSPQTDEPIDEACVLDENRALLMPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLF7</accession>
    <name>A0AAD8YLF7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Corrinoid adenosyltransferase MMAB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP:co(I)rrinoid adenosyltransferase MMAB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_001313</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Converts cob(I)alamin to adenosylcobalamin (adenosylcob(III)alamin), a coenzyme for methylmalonyl-CoA mutase, therefore participates in the final step of the vitamin B12 conversion. Generates adenosylcobalamin (AdoCbl) and directly delivers the cofactor to MUT in a transfer that is stimulated by ATP-binding to MMAB and gated by MMAA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cob(I)alamin-[corrinoid adenosyltransferase] + ATP = apo-[corrinoid adenosyltransferase] + adenosylcob(III)alamin + triphosphate</text>
            <dbReference type="Rhea" id="RHEA:56796"/>
            <dbReference type="Rhea" id="RHEA-COMP:14743"/>
            <dbReference type="Rhea" id="RHEA-COMP:14744"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:60488"/>
            <dbReference type="ChEBI" id="CHEBI:83228"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:56797"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the Cob(I)alamin adenosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLF7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008817">
        <property type="term" value="F:corrinoid adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009235">
        <property type="term" value="P:cobalamin metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1200.10:FF:000001">
        <property type="entry name" value="Cob(I)yrinic acid a,c-diamide adenosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1200.10">
        <property type="entry name" value="Cobalamin adenosyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016030">
        <property type="entry name" value="CblAdoTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036451">
        <property type="entry name" value="CblAdoTrfase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040807">
        <property type="entry name" value="DUF5522"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029499">
        <property type="entry name" value="PduO-typ"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00636">
        <property type="entry name" value="PduO_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12213">
        <property type="entry name" value="CORRINOID ADENOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12213:SF0">
        <property type="entry name" value="CORRINOID ADENOSYLTRANSFERASE MMAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01923">
        <property type="entry name" value="Cob_adeno_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17653">
        <property type="entry name" value="DUF5522"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89028">
        <property type="entry name" value="Cobalamin adenosyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cobalamin adenosyltransferase-like" evidence="12">
        <location>
            <begin position="207"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="168"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="174"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00051988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00056747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00071654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00075216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1747350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="426" mass="46830" checksum="86D406E8124E51B7" modified="2024-05-29" version="1">MISKAVSSISRAALNATKITHNTYRFSSCLPRTSSSSIDQVTIAYTSLDLQKMAETKTNNDEAAITDIEDLHRHAIMNKQSTYIDPATGFTVFTELPHLKRGRCCGNMCRHCPYGWSNVRGTSENGTNGRAISGDRECTGRLVKQILDGTYYGNDEDTITKLEPNGAKLSTLNTSPPATTDASTSATISRGKGGRAGGTLTSKNVPYTRNGDKGTSQLFTGERRKKDDILFEALGTVDELCSVVGVVYAELVAAEKRTSNDNATASTAKSMYGELPEQLLEVMSRLFDVGSHVAKPEPNIKEMDKSQKGNKGFSSDHTAVLEEWIDAMTEELPELTSFILPTGSIASSNLHVARTVCRRAERRMVPLVQEEETCDPDALAYVNRLSDYLFTAARYVNFCDGSDETQYRKARSIVQRERIIVKLNDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YM68</accession>
    <name>A0AAD8YM68_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_002017</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1748054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YM68"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Vaccinia Virus protein VP39"/>
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        <property type="entry name" value="TPR-like_helical_dom_sf"/>
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        <property type="entry name" value="METHYLTRANSFERASE"/>
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    <dbReference type="Pfam" id="PF08242">
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        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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            <end position="25"/>
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            <end position="589"/>
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            <begin position="311"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase type 12" evidence="3">
        <location>
            <begin position="420"/>
            <end position="519"/>
        </location>
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        </source>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1748054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="589" mass="65459" checksum="61A10039C461CA37" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMQ5</accession>
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        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="4" type="ORF">QTG54_000039</name>
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    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
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            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
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                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748100.1"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="NUCLEOPROTEIN TPR-RELATED"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    </feature>
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            <end position="1345"/>
        </location>
    </feature>
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            <end position="179"/>
        </location>
    </feature>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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            <end position="1332"/>
        </location>
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            <end position="357"/>
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    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1217"/>
            <end position="1228"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1748100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1345" mass="133722" checksum="B8B26240731B2D27" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YN66</accession>
    <name>A0AAD8YN66_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TFIIS central domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_000140</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
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            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
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                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
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    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        <property type="protein sequence ID" value="KAK1748201.1"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
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        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0006351">
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        <property type="project" value="InterPro"/>
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    <dbReference type="InterPro" id="IPR001739">
        <property type="entry name" value="Methyl_CpG_DNA-bd"/>
    </dbReference>
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        <property type="entry name" value="TFIIS_cen_dom"/>
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        <property type="entry name" value="TFIIS_cen_dom_sf"/>
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        <property type="entry name" value="IP08861P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11477">
        <property type="entry name" value="TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07500">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46942">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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            <end position="2219"/>
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        <location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="2240"/>
            <end position="2270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1748201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2495" mass="278105" checksum="6B0D05D5A888FCBC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPP3</accession>
    <name>A0AAD8YPP3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pentatricopeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000954</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPP3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051240">
        <property type="entry name" value="Mito_RNA-Proc/Resp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47933">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1749015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="902" mass="100419" checksum="F7112B45D4CEFD09" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4N1</accession>
    <name>A0AAD9D4N1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015645</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000046">
        <property type="protein sequence ID" value="KAK1733602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4N1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="341" mass="38437" checksum="2C352FE2AD7D16C0" modified="2024-05-29" version="1">MATNLKRKANDSGDAIEDCQLSLLDEQLGNPLVYVGSFLTGKDFSTFLSASISSRHVKDHALRTHLVSVFVDIHKSMTDRCNVFLSNIAAPTTMVTLFNDRSTNLKRAIDTLRNYMYPNLPRIMNAVSEWSALLDYCELLPLRLSKARLDQDGPTQPLWIVGAGEFGSTKSPSILSVPSQTWRPGLVFMAEKWMVDCPRGYPYLQYDISSHLFSSESIAHGAAVMSWKDGDYLAHMHREIVDITAGGEIYHEFPVDFEVDDNAHYSLLSWIPKANSESPMGENVRVALGNSESLNWMLKGTKFDNNMLAIMQIEDEGIPEDHMDGFYVRIIKLMVEAEQWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D590</accession>
    <name>A0AAD9D590_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000040">
        <property type="protein sequence ID" value="KAK1734307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D590"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="114" mass="12406" checksum="81E0C535AE2488BC" modified="2024-05-29" version="1">MKTEEAASYSSASSNSISRRMTMSNSKPKLLLLNPVAVLLGLILNKDWKMIRTLIAATSPDCFRDLASSISSCSQHKLNGMTLLHAIIRDNPPLDIVANIIRLCPEMAATCSIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5D5</accession>
    <name>A0AAD9D5D5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_015647</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000046">
        <property type="protein sequence ID" value="KAK1733604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5D5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="3">
        <location>
            <begin position="162"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1733604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="301" mass="34427" checksum="DB3D5FDE397C2220" modified="2024-05-29" version="1">MAARKRNASARSSDSNKPANTKPSKTSRATANQNAQSNSSNTKSTAASRIMNILVSLFIIAMLNPLLFNALDFLQSYNNIQHKLTPKRDFPYEWETYTYNDIREYFNCRQRSKDLDKPLPTLDDWNLLRKAYTLIVDSAKTWNDPVPPTEGYSFEQGKAVPPPYYAKQSEGKGRGLFASRDIKKGELVHNGEISDIVFPGYDAIKWKEFVFSLPRDFACDCTDWHWMQMKHEDDDYHMVAALDISVLMNSGGEEFGPGRTPNVLPEDKYSGKQFALRDIVKDEEILTDYDAYWTDWSEVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5M7</accession>
    <name>A0AAD9D5M7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sel1-like repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014426</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5M7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="164" mass="17857" checksum="A2CAC945A8A59E27" modified="2024-05-29" version="1">MKRVAANDRVAIHQEGVKHHQSGDFASAFEYYTKAAELGDAEAHYLLSLLYGKGQVVEKGEKKGLYHLEEAAIAGHPEARNILACYEERKGRIDRAVKHYIIAANLGYDLSIQSLKGCYKGGKVGKEDFAAALRRHQAAVDATKSPQREAASIAQAAGKFRSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5W6</accession>
    <name>A0AAD9D5W6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">TLD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_015162</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5W6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006571">
        <property type="entry name" value="TLDc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07534">
        <property type="entry name" value="TLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00584">
        <property type="entry name" value="TLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51886">
        <property type="entry name" value="TLDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TLDc" evidence="5">
        <location>
            <begin position="709"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="domain" description="SAM" evidence="4">
        <location>
            <begin position="995"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="564"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1734159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1129" mass="126294" checksum="7A2D5C13BCB045AA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6B8</accession>
    <name>A0AAD9D6B8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">aspartate transaminase</fullName>
            <ecNumber evidence="4">2.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Transaminase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_013640</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.1" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6B8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004069">
        <property type="term" value="F:L-aspartate:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000015">
        <property type="entry name" value="Aspartate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000001">
        <property type="entry name" value="Aspartate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000796">
        <property type="entry name" value="Asp_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006719">
        <property type="entry name" value="PRK09257.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879:SF22">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00799">
        <property type="entry name" value="TRANSAMINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="6 11" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041999901" description="aspartate transaminase" evidence="9">
        <location>
            <begin position="21"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="10">
        <location>
            <begin position="59"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1735477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="440" mass="48224" checksum="835942813C61C92E" modified="2024-05-29" version="1">MTMMFKSLAATLLLSSATQAFSTVTKTDMSPSYLSNVPEGPPDAILGIAEAFKSCTDERKVNVCVGAYRDSTGKPWILPSVRKAEERLLVDPTVNKEYAPIAGDAKYVDLALGFAYGTDADMTKLAGVQTLSGTGACRVGGHFLSKFVPKPEGMDKVPIYIPNPTWGNHIAIFNNCGMDVRRYRYYNSKTNRLDYDGLIEDLKEAPEGSVILLHACAHNPTGCDPTMEQWKDISDLIKSKKHHCFFDSAYQGFASGDAEADASALRLFVSEGHNVVLAQSFAKNFGLYGERTGTLSVVCNSLEERSAVMSQLKLIIRPMYSSPPIHGSSIVKTVLTDEELTAEYYDNCKEMATRINAMRVKLVEVLKEVGSEHDWSHVTEQIGMFAYTGMNSDMCDELTSKYSIFLTRDGRISLAGLNDGNIEYVAKAVHDVTAGKSITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6J7</accession>
    <name>A0AAD9D6J7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_013453</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6J7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="545"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1735747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="587" mass="65614" checksum="A246010C644999DC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D743</accession>
    <name>A0AAD9D743_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">tRNA (Adenine(37)-N6)-methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_013943</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the tRNA methyltransferase O family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D743"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09281">
        <property type="entry name" value="UPF0066"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.70">
        <property type="entry name" value="YaeB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.10">
        <property type="entry name" value="YaeB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023370">
        <property type="entry name" value="TrmO-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040372">
        <property type="entry name" value="YaeB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036413">
        <property type="entry name" value="YaeB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036414">
        <property type="entry name" value="YaeB_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12818">
        <property type="entry name" value="TRNA (ADENINE(37)-N6)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12818:SF0">
        <property type="entry name" value="TRNA (ADENINE(37)-N6)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01980">
        <property type="entry name" value="TrmO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118196">
        <property type="entry name" value="YaeB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51668">
        <property type="entry name" value="TSAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TsaA-like" evidence="3">
        <location>
            <begin position="91"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00033753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1735329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="363" mass="39594" checksum="D698A1C0D1F30E44" modified="2024-05-29" version="1">MKQSNSSSTALAVSASAAVAATAALLYTRRQFKKQEAIISKLEETRQAERKGRIRAEMKLRTHLKSQEINKAADAADQGDISTNEHNDLQLQCIGKIVSPYTKRMGTPRQGALVPTGKGYIQLEIPIECVEGLELYSHAWVLFSFHANTDMPTAKADARGFKNLSKTKIRPPRGNGIKVGMLATRSPHRPNNIGLSLVKIVSVDKKGKRLHIAALDLVNGTPVYDVKPVVPWDEPGHFDGEKLKVPTWVSQDDELKSVAFSPSAREQMVKLVKDGKLAPVYSKKTGLDDAIKTIQEVLAQDPRASNTNTNKRGSESANKVYSILFASIEVQFRVDGDGVVVSEVMDADLSKAEIVDGIPVLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7W7</accession>
    <name>A0AAD9D7W7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">PPPDE peptidase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_013215</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DeSI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7W7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101005">
        <property type="term" value="F:deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1720.30">
        <property type="entry name" value="PPPDE domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008580">
        <property type="entry name" value="PPPDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042266">
        <property type="entry name" value="PPPDE_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378">
        <property type="entry name" value="DESUMOYLATING ISOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378:SF80">
        <property type="entry name" value="IP06716P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05903">
        <property type="entry name" value="Peptidase_C97"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01179">
        <property type="entry name" value="DUF862"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51858">
        <property type="entry name" value="PPPDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPPDE" evidence="5">
        <location>
            <begin position="397"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="55"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="177"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="235"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="71"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="268"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1736079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="692" mass="75547" checksum="F191434A00EFDB07" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8E8</accession>
    <name>A0AAD9D8E8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phytanoyl-CoA dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8E8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="218"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="444" mass="50852" checksum="6B7F93C0CFDA4D5A" modified="2024-05-29" version="1">MHPLISRWSDEDFWRKLCPHLSISTNGDGDSCTSTSNVQPKYYEQKERQELLDRLIDDGYALLDEPCNDGLKEKVGKAISNLELQHSIPATFALLFNETWQLAAESKQLLLQKQNEGILQSHGKMRFNFDMLAWHIDPRRKQVGFSPHRDRQPDTLDALKQSFYSDGQAKYITHWIALADANPNNSCLYVIPKQFDPGYLEGDDPPESSTDESKTDSENNTESSSSDSGSFSDPLSRALPTKQSYQNIRALPRKEGESIIFTHRILHWGSAGNPRASKLHPRVAISFVYSDVDYEAPYLTNFSMDDDKLPPFSLRLLLVCSQLLIYYQRFDNLTTQHLRACYEYCKQHADELNDAYRKKVFVEFVKAMKERRDGVEDDGDDDKAALVKDKEGSRNDNDGDDSDDEEAMLEAMLENSDQFDDDFDDEYYDSDDCGKHKSKRARIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9B4</accession>
    <name>A0AAD9D9B4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9B4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="299" mass="33304" checksum="312DFD330799B023" modified="2024-05-29" version="1">MSMEDILQDPKTTWEEIRSAMRSQGHATNGGIVMALVTASEALPSQETGQEEHTIAPHVVVETATKPEEDDEGSIQYSQLDEFLSNDTPVNFGYKPCKTRKPATNNPRRGIISKQQGIEQHSILLTPQLQLLVNSSLASVDMMDFGVDNDAVTYSMETLNEIESRRGTECSITANESSSCLTNGFLDWNHDDESSANPSQHVGRDESCPDNKSDTHKSEHPSAPEVRRRESWHIEDHDFEPVVKHPVIPKMLHRLSSGTFDTVSSLFSRLSHELGPGTSFPHVVDVTLKSQQQMRSKRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9D0</accession>
    <name>A0AAD9D9D0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dehydrogenase/reductase SDR family member 12-like protein</fullName>
            <ecNumber evidence="1">1.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011789</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.-.-" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9D0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052992">
        <property type="entry name" value="SDR_member_12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44656">
        <property type="entry name" value="DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44656:SF7">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="272" mass="30342" checksum="113783370ADB634F" modified="2024-05-29" version="1">MVGLIRQGIATTQFFLFGKKNCTQTGYLKHMQQYKDPGIGKEIATYAAAKGGNVYILCRNEERAKIAQKDIQEKTKNKKVTVLLADVGEPSHIERVVKEFTDKEDKLDCLVCNAANEARVVYVSSGGMYNSKFPEWEVAASSGKHESDYNGNIAYSYAKRGQVLLAERFTKDYPEVHSFQHIQGGSGQQPLTAPTVIMQSISSHFVICGRDLKVLLADSYTKKNLESGAFYLDRSPQRKHIAGLFMTDGSFTKNSEKEVDVMMKKLEECVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9I2</accession>
    <name>A0AAD9D9I2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000024">
        <property type="protein sequence ID" value="KAK1737653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9I2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042135554" evidence="1">
        <location>
            <begin position="31"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="441" mass="48936" checksum="C14B9F1CE95CBEC6" modified="2024-05-29" version="1">MLHSSVCCCFWRTIAVIIVAIISQDEVVSAHKLSHLTSTFIPSSSTPSLLRHRHQGSCKNNSCSGSFSGRIKLVDTATHVLCSSSSPISSSSQLTSPSPWSPGKWKLTLDFGVDEPKPDSSSLEQNENRIQLHKLLGDNWGAEGGRLILPFEVIISSETSSTDKNGRGQANPSVEMTWLGGKPTGSIQCIPKETNDDENDDEQIHHATYINNKGEQRVQISPGLWRNEPPTPILPSFTKILSGQASSLRMYLKLVNSIERNTISFPEDQLLLLKSNTFRTTQYASGIQTVLPYQYAKEQSQQALEEQLNHETGDRRLDGSDLLETAAAYKDIAALVMERDERRRRWKEVEGVLPKISGPSIKIGRASTTEELLNDVKRWGIWPGDTELMTVERGVVLAAVSAKEKKQSIFPWMQDSNSEEMVVVGKWSATPLFDERSDGNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9I7</accession>
    <name>A0AAD9D9I7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011592</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9I7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="438"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="513"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="669"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="222"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="451"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="679"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="792" mass="83676" checksum="A5206878A08863D1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9T0</accession>
    <name>A0AAD9D9T0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010833</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9T0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="369"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="517"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="583" mass="64249" checksum="3D8F0EF5DB6B3F05" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9V9</accession>
    <name>A0AAD9D9V9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_010025</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9V9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1739482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="178" mass="20931" checksum="760B533B2F93BBC1" modified="2024-05-29" version="1">MVSLTNRLVDVIPKCRISLALEQSHKRRQDRIMAMNVSRKTVFLTRERGSGIFVTIWEGKAQKQSHMFSEDGLVLDIPCQVEFHRYIQWHNMAFMSTWDLGIPTLIVHYESYTNNFNETKDALLEFLEQDEVADAPTFITGKRYKDCYTVDEIDAVSKMFDRLALRETWQHTKQHFGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DA86</accession>
    <name>A0AAD9DA86_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Nitronate monooxygenase</fullName>
            <ecNumber evidence="9">1.13.12.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_009646</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.12.16" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DA86"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07596">
        <property type="entry name" value="BAR_SNX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000002">
        <property type="entry name" value="Transmembrane protease serine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015404">
        <property type="entry name" value="Vps5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF91">
        <property type="entry name" value="AT26814P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09325">
        <property type="entry name" value="Vps5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="Peptidase S1" evidence="8">
        <location>
            <begin position="644"/>
            <end position="888"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1739887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="944" mass="102128" checksum="69E5917EDFF45466" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAK0</accession>
    <name>A0AAD9DAK0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Neurotransmitter-gated ion-channel ligand-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_009331</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAK0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="427"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Neurotransmitter-gated ion-channel ligand-binding" evidence="7">
        <location>
            <begin position="165"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="526"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="549"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1740381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="560" mass="62718" checksum="13E420922399DFC5" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DB86</accession>
    <name>A0AAD9DB86_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008398</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DB86"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008823">
        <property type="term" value="F:cupric reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052851">
        <property type="term" value="F:ferric-chelate reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015677">
        <property type="term" value="P:copper ion import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051267">
        <property type="entry name" value="STEAP_metalloreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14239">
        <property type="entry name" value="DUDULIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14239:SF0">
        <property type="entry name" value="F420-DEPENDENT NADP REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="325"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="369"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="433" mass="48566" checksum="F5253F7417F7C9D5" modified="2024-05-29" version="1">MTNVTFEEKSKVVFVGCGDKAHGFARMHDLHSNKHGKYQLVFTEPMPTKPIDPFDSDYVTIEHFPECLANADIVVIVIPSYAIDSFLIQNYTLLKEGSKGYLAALNITSDHWVKAFNDTGAIQEMQNSLNSKMKLTTSVCGPSDQCVKKIAALAKYLGYSPTVVPIDQYKCLQSCQTTLAGTFTYVTVQVSGRPHFQWYTLLARHSSKMFAWTAIWGFSLSLLPGTCIRLLKQVTYMDTTPRFLIWGCSIRKQVGLLSLYFVLLHACMMLLIFGGEYFGFLIDDGYMEWNTEASMLTAVLSTSLFTITGIASLPSVAHEMNKAQFMLVFGPVVWSALALGVMHVMFLGVPSWTDTPRSRYSWARGMPPVTLMASVLPLLVMFIKAVQVCHASMLRAKNWVTSRHQVSSIHASDHLFVIDDEVEEVFEKSRMYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBC7</accession>
    <name>A0AAD9DBC7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cdc45-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_008339</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDC45 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBC7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902977">
        <property type="term" value="P:mitotic DNA replication preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003874">
        <property type="entry name" value="CDC45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10507">
        <property type="entry name" value="CDC45-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10507:SF0">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 45 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02724">
        <property type="entry name" value="CDC45"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="185"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="290"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="204"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="299"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1741087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="779" mass="86410" checksum="D5164CD36BDA9B84" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBJ2</accession>
    <name>A0AAD9DBJ2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphoadenosine phosphosulfate reductase</fullName>
            <ecNumber evidence="6">1.8.4.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_007745</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PAPS reductase family. CysH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.8" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBJ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004604">
        <property type="term" value="F:phosphoadenylyl-sulfate reductase (thioredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019379">
        <property type="term" value="P:sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23945">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00063">
        <property type="entry name" value="CysH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004511">
        <property type="entry name" value="PAPS/APS_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00434">
        <property type="entry name" value="cysH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002537">
        <property type="entry name" value="PRK02090.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46509">
        <property type="entry name" value="PHOSPHOADENOSINE PHOSPHOSULFATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46509:SF1">
        <property type="entry name" value="PHOSPHOADENOSINE PHOSPHOSULFATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphoadenosine phosphosulphate reductase" evidence="5">
        <location>
            <begin position="136"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="329"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="371"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="339"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="393"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1741267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="405" mass="45739" checksum="5888EFE1341B7625" modified="2024-05-29" version="1">MLSSSTLSSFDYEVPKVDDASDMSSSSTASSRFTMFRQNKAVKWILGAVVKLVIMSVLLRMQRQRKVDDSTNDNATSGSSAENKQLDKLYAMPLPTTPQELSEVNSELAGLDPEFILKWAHHHLHDSPELGDSHPLVQATSFGPTGLVILDHLALHNLLDTIPVVTMDTLHLFQESYTFYETVQSHYKSPLHLTITKPLDMIEEPLMSKAEFEDAYSANLWKDDPKLYTKVTKLEPMQQKLEEWDAVMWITGRRRSQGGERGKLDVLEFEPYPQGSDMSSAAKSSPFHSSKGRWKLNPLAYWSYDQVWSYIRNNDVPYNPLYDQGYTSIGDEMTTSKPDNADEGERSGRFAGFGESNKECGLHVDFDFEAASDNKFDQEEEEEPEGAENVTCDIDKARQGECSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBQ0</accession>
    <name>A0AAD9DBQ0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBQ0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="191" mass="20003" checksum="FA049193C121407F" modified="2024-05-29" version="1">MTSNNTNANNTNNNGGNIDNTSNGVMAANAASAARLTNRSDNVIVNGSAVTGQELPGQANNAINNGVIVNGSAVNGQEPSGQVNNGVAARDDNAGIFQPLAPANRPIAQCNLGGGVLARDLRLGIFARDDYSNWATIPSRRRDPSRHRVPSRRRVPSRNNRRNGGISGGAGTGGVHNRNNRTGIFNPRDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCA1</accession>
    <name>A0AAD9DCA1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Derlin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_007695</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the derlin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCA1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007599">
        <property type="entry name" value="DER1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11009">
        <property type="entry name" value="DER1-LIKE PROTEIN, DERLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04511">
        <property type="entry name" value="DER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="254"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1742122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="314" mass="35577" checksum="A27FB4E593D799BD" modified="2024-05-29" version="1">MNNFFDARGGGAAGGGPMQWFHSLPPVTRLWLGSTLTVTALANFDVLQWTDLDLTHLTDVLGKSSNTTNSSSVLLFGRLEIWRLLTCFLYIGKFGWHSIINLHLMTQISSRYESMGPICTRRIFVPHQNNPQLLQQQQRNNQNNNYPYYSKGETSDYICALLFGVTGILLSQFYLLPYLGDTFHHHYRFFHRHLTFYTLYIWSKHYPQHNVNLFGVVMKAAYLPFAYLVMGYALSNGEVVPMDMIHGMFVGHLYYYLACVVPTVLGRGRVVIWTPGVLIDLCHWLEGRRVGGVNDDDVDGGEPIVVDTDGVIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDC4</accession>
    <name>A0AAD9DDC4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006107</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDC4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="220"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="313" mass="33797" checksum="C52FD35A0DB5C4FC" modified="2024-05-29" version="1">MAAYQSSSTTTTGRPPVQESYGGTTDSSSNVGLPNSARGEGTTTSEMVAKLRFFNCAVCAYLILFHFLPIVINPIRLALLIKSPVRLVLEAIVGIVAISMLITEAQVPIFAEKVLLLFQKCRVGNVQLIDLDVARGRVVAIVVMTLATGMVNHLNSHHSNNGNNGIVSDQTVMDDSQQSMIVNGTNSSAALNETINNIDNITSTSYHPASTYNNDDLNAVMGFLCAIVYSCIFSLSMWILLALLSYTLYVMREYPSYAEYKAFSHVQNDSSTSSAARPLSPASGRSWVSNIPDFSSITGGGYQSVDNPIQMNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDM3</accession>
    <name>A0AAD9DDM3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sodium/hydrogen exchanger</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_007381</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDM3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015386">
        <property type="term" value="F:potassium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015385">
        <property type="term" value="F:sodium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051453">
        <property type="term" value="P:regulation of intracellular pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098719">
        <property type="term" value="P:sodium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018422">
        <property type="entry name" value="Cation/H_exchanger_CPA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004709">
        <property type="entry name" value="NaH_exchanger"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00840">
        <property type="entry name" value="b_cpa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110">
        <property type="entry name" value="SODIUM/HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110:SF187">
        <property type="entry name" value="SODIUM_HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0050">Antiport</keyword>
    <keyword evidence="6 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0915">Sodium</keyword>
    <keyword evidence="8 9" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="3 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042211130" description="Sodium/hydrogen exchanger" evidence="11">
        <location>
            <begin position="19"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="73"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="114"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="12">
        <location>
            <begin position="2"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1741808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="369" mass="41195" checksum="89C0662C1914833C" modified="2024-05-29" version="1">MEALLFGALISAVDPVATLSIMGSPELQCDTLLYSLVFGESVLNDAVAIVLFKTFHKYYNSEEILDGSVIPAALFSFFTMTVLSIFVGVSLGLLVSYIYKHTSISEFPKLEASLLYLFCYLCYATAEAFGLSGIMALFFNGVVLSHYNSYNLSTTAQTTTEQFFATVAVTMETIIFLYMGLSVFTGRFQNWDIMFSLLGLLFCLIARALNIFPLSLIANCCRRKGENRISLKTQCVLWFAGLRGAIAFALSMNMPGPNSDSYASATLFICMFTTIVCGGFTENILTRFGMKQGLDNDDDAHDDFTGVENLISTESPLARRLSADLQERYRSFWHDFDDNYMKELFGGDRVPDRQAGDYELSEQNDLYDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DE63</accession>
    <name>A0AAD9DE63_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_006973</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DE63"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1742408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="201" mass="23277" checksum="B3E5EB0A2DFB6873" modified="2024-05-29" version="1">MKCSKCTRCSSARLCARGALTSCSKPDIDDDNDCGAPNISPQYITPETAEYFKNKHDEEFEKPKRVMLATQKWVLEKSSNYLGTVQNFLPNSPLPRALAKNVLPNKFDKNSDEDKYQIRDLEEIPTEEQTMEDKVAYQLWHGAEEIQEKIEDVRVRMFWKPTKDLDKVLDGKDKYNVEGEEKEIDIQCNSWFEEDANAPWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEK4</accession>
    <name>A0AAD9DEK4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PGR5-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006410</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEK4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016730">
        <property type="term" value="F:oxidoreductase activity, acting on iron-sulfur proteins as donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009773">
        <property type="term" value="P:photosynthetic electron transport in photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039987">
        <property type="entry name" value="PGRL1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31032">
        <property type="entry name" value="PGR5-LIKE PROTEIN 1B, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31032:SF1">
        <property type="entry name" value="PGR5-LIKE PROTEIN 1B, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042102095" evidence="2">
        <location>
            <begin position="29"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="321" mass="35506" checksum="04EF152AD5789411" modified="2024-05-29" version="1">MSAATKSSIILALWAATTVLLQSSSCSAFSPSPLNRRTTTALNLDGPDPGTKLVSNRKEIAFDGSRFFETGVEDEDCIPTQEYCLVDPNSGAPIRLSVEEKERMFLDALQSYYVSGRQVMDDSEFDALKEDLAWNGSEVVNLNRREITYLEAMQAYIKGEPIMTDVEYDQLRDELRENGSSIAVDTEPKCYIESGVCTVTFQQDKFRNNLLYLPMLSIIGFLWLGIGYEILGGRVNPLVLTAFGAPVIGTVGKAITDTFIFPDNFVAYGPCPTCEAENRIYFGGILGVEGFDKQGKIKCKNCKSEVIVMKRSLRASTLPKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG08</accession>
    <name>A0AAD9DG08_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">THO complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_004756</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the THOC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040007">
        <property type="entry name" value="Tho2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021418">
        <property type="entry name" value="THO_THOC2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021726">
        <property type="entry name" value="THO_THOC2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032302">
        <property type="entry name" value="THOC2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21597:SF0">
        <property type="entry name" value="THO COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21597">
        <property type="entry name" value="THO2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11262">
        <property type="entry name" value="Tho2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11732">
        <property type="entry name" value="Thoc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16134">
        <property type="entry name" value="THOC2_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THO complex subunit 2 N-terminal" evidence="9">
        <location>
            <begin position="265"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="THO complex subunit 2 N-terminal" evidence="9">
        <location>
            <begin position="679"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="domain" description="THO complex subunitTHOC2 N-terminal" evidence="8">
        <location>
            <begin position="815"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="domain" description="THO complex subunitTHOC2 C-terminal" evidence="7">
        <location>
            <begin position="1135"/>
            <end position="1467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="439"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1486"/>
            <end position="1650"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1213"/>
            <end position="1240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="441"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1486"/>
            <end position="1500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1507"/>
            <end position="1542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1576"/>
            <end position="1614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1621"/>
            <end position="1639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF11262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF11732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1744223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1650" mass="182097" checksum="F389816687AF3657" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGD6</accession>
    <name>A0AAD9DGD6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Short-chain dehydrogenase</fullName>
            <ecNumber evidence="3">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005176</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGD6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43639">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G02870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43639:SF1">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="241" mass="25891" checksum="48745B69E4DA7A38" modified="2024-05-29" version="1">MEYLSPATAAVDNCVIEFIKADLSNVEQTEALIPKSILALQKAVNAAATTARGNLATTTATSFNEQYDTNVRAPFLITKHATQHMMEMNLERGLGSIVNICSVASKGGAPFILGYSCAKSALVTLTKNNAAELAPKGTRVNGVDMGWCLTENEDKLQSANAGADWWKNADESVPLGRILRPVDVAASVLFLLSGASVMMTGSIIEDSNTLLTKYDVTGTHLWYTLFSQDIIYRGVTATSYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGE7</accession>
    <name>A0AAD9DGE7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein S-acyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGE7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="208" mass="23564" checksum="B98DFABF3C7CF734" modified="2024-05-29" version="1">MTVVITGSCVRVLSECYLEGVREERMEHHHELGGGGGGNGTEYYEDDLWMWSNGTNHTLQQQAPPVHRFHYHIALRILSKQPIELAFGLFSLLCAWSITSLTCFHALIITLGQTTNERVRGVYQYGGVMNPADRGCWRNWMEMLWRKVPESRLPSNFSDVVDLNGATRRSRSSGCGECSEAPIVLEESVWPGWQESRLVPQPKVKSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHX0</accession>
    <name>A0AAD9DHX0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_000360</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC35F solute transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHX0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009262">
        <property type="entry name" value="SLC35_F1/F2/F6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13146">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13146:SF3">
        <property type="entry name" value="EAMA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06027">
        <property type="entry name" value="SLC35F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="15"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="244"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="343"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1748421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="402" mass="45066" checksum="DB1F29244C845742" modified="2024-05-29" version="1">MSNLANVHKCGLNEVILFLLAIIFGTGCSICSKTMMGLHGTNGTVDETGIPTTSLTSKMKAESNVDNASKEIPLWMYFFLAIPAIFDLAATALCMMGLQYLDVSIYQMLRGSGIIFVALMKQHVLKDHLHQYHWVGVFWNVVSVVIVGGTAMLASGGDGEGSNNSNTSETFWGVCLLMSGAFVQAVQFVFEEHVMTMDTPAPPLLLIGMEGLWGTILSICVMSDHGSYEDPFNTWAMFTHSKNIQVAFFIYFFAIFFYNLFAVLVTFKLSSVWHAILDNFRPITVWGTDLFIFYYINPLFGEVWTQWSYLQIFGMAVLLYGTAIYNAPNAGSLLLEGQWWAFGINLSSEYEQVKRELEQAEIDAKWEAKRQEFKVRTRSSFIESPRISIHTQALRGIGAQHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DII7</accession>
    <name>A0AAD9DII7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Complex 1 LYR protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001382</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DII7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20251">
        <property type="entry name" value="Complex1_LYR_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="2">
        <location>
            <begin position="7"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="95" mass="11099" checksum="591B89B8B964F94F" modified="2024-05-29" version="1">MASQSTELLHLYRRLLRSCATYPSKNRWGIYEAIREEFRDNRAMNPDDPKTQKQIQVAYKGLGQLRMYDTAQLSKGNPESPNWEVTLEQNPMPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJH6</accession>
    <name>A0AAD9DJH6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001968</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1748005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJH6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42103:SF2">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42103">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="1">
        <location>
            <begin position="92"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="261" mass="28630" checksum="8CF404CAB15332AE" modified="2024-05-29" version="1">MPKPTVSIHTITTSYGASDIRVFEPSSYDDILGTVVTVHPWSFLGGGEHNTIGLARNMSTRGWRVITFKLKSTPLYLGGAIGGILFRHYHEVNHVAEVVEWAFEQYHTKNDTSDHRMVLLGSSAGAPFAGSAMAKIQQHQHAKIAAFIAVGYTFGHFASLGFGRHFSSVVGNSASNFCGSSSSSAEDNEEIPPKYFIMGENDEFTSVEQLESMVARMKSVNPNCKVEVDVVPSVGHFQLESPNYDPVVAEKVVQWLQDTIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJQ3</accession>
    <name>A0AAD9DJQ3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJQ3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="482" mass="53426" checksum="CAD7316FFF21A223" modified="2024-05-29" version="1">MGRTPAWWKKRHSRSNSSGGDLTLPAAPMDTSCAADVKLERFPSESSEGSFPSHQLKKGRSNLSASFSSTSERSYESTEVVEEQRHVDECSDHPEPPLVDDVITEHQSTEADGSNGVTIPEKPSESAAEENQFSPGDDGDVLDKPTHRSRRVHIDATEEEAPSIERTGTEDSGEGSMDSSAADTQGSSAQATLAMSVTTSKTDCTDYTDDGILRDDEGNPVDLAEAEENMLRDDEGNIIDPKTLVTRESFLDLCDEYCEDHLHTLGADNTQDESEIDEDTYVRFTIEAIVSEMITHIEGNDQRNLNSETCNEEDYEEPLKEGCNKEANAKEIDEADENEDPNEADDNVEPTLGRGLKPKRNGNASGRNRSRQIRWGRACPQQGADDTVHIMFNNTLSTLDEEASCIIDEDSAEETEDEKSNMSHKSTRSEKFFKARWNYSLQVMRSEASTAQLIDARDEIDDMIRPKFVPDDRSVCSDEGTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2LFT2</accession>
    <name>A0A7S2LFT2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004138</name>
        <name evidence="1" type="ORF">SMAR0320_LOCUS11316</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="HBGZ01015822">
        <property type="protein sequence ID" value="CAD9603890.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S2LFT2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CAD9603890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="263" mass="29547" checksum="6E5ABD002AE9E5C7" modified="2021-06-02" version="1">MFLLVQRYASSNIIDNACTSFCNAIQEPGMLSNVFLANQGLFTSNLNPGSSTARMPHVFDIISVMFNIVTHHSPVDGAPNNSEICLFMSGIESEVGLFMRMNPKFFFITCRILTDFTNVDSFVACANVSFPVVFKGGHYYIIIGEENTPIYRVHQPVKLFFTFEGKLILKRLLRRNHSHTGEFDFHVNKDGKQAVYCIPNFASAGVFPGGRWDDCNSAEIESMMPHPLVKQPIVPDTHKFSVQVLELSDSENIVDIFFDGNEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2PJ90</accession>
    <name>A0A7S2PJ90_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_012729</name>
        <name evidence="4" type="ORF">SMAR0320_LOCUS10960</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="HBGZ01015356">
        <property type="protein sequence ID" value="CAD9602858.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S2PJ90"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042409326" description="SET domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="3">
        <location>
            <begin position="48"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CAD9602858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1736707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="375" mass="41330" checksum="19A8AE876692E8D1" modified="2021-06-02" version="1">MKLLACVAYFLVAGPCNAFSTTSVGSESRYADLKDWLLSGTDDSFISPKLDIRPSTRGGLATGGYGAFAGEDIDEGEILLKIPVAKCVTLQDALEDLECGPSFANLLKKAGPGSDTVVIAGYLAKEYLLLKEFDRRISEGATADDDSEMRRLANIKFAAYLRTLPWGRGVNAQEHVLFWKDEDVDALLEGSLAYKDATETRATVKMATKVLNAIISPVIRKARAEEEPESKDEGFRFPWQQEPEPESSDEEILEGLEDAVRGAFVIMLSRSFAETVGENTQEDRLEPLLDMLQHSNAPNTECLVKGDGGSIVEVRACKVITSGDELFNRYKSEEDENMPYHKFFTRFGFVPGVVEPVADLIAARSTIFFPQRAEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRG4</accession>
    <name>A0AAD8XRG4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein S7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_017111</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="mitochondrion" evidence="5"/>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000083">
        <property type="protein sequence ID" value="KAK1732070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRG4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="entry name" value="Ribosomal protein S7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_uS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_uS7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_uS7_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="Ribosomal protein S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS7" evidence="4">
        <location>
            <begin position="3"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1732070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="139" mass="16845" checksum="ED70BA5272DF5367" modified="2024-05-29" version="1">MNKKIINQLLLKGKRTTSEKIWLKSIKFFYKLFNKNHKEFINRALINVTPLLKVKQLKQKNKRSQLKEFPYIVNNANRISSTLKFFLTKTNNKDEKKMHKKLINELLLATKNTGTNISKKKSLYEYAFVKKKYFYYRWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XT72</accession>
    <name>A0AAD8XT72_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">thioredoxin-dependent peroxiredoxin</fullName>
            <ecNumber evidence="1">1.11.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Thioredoxin peroxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_016301</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the peroxiredoxin family. BCP/PrxQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.24" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000055">
        <property type="protein sequence ID" value="KAK1732970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XT72"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03017">
        <property type="entry name" value="PRX_BCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050924">
        <property type="entry name" value="Peroxiredoxin_BCP/PrxQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42801:SF4">
        <property type="entry name" value="AHPC_TSA FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42801">
        <property type="entry name" value="THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 14" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041917201" description="thioredoxin-dependent peroxiredoxin" evidence="12">
        <location>
            <begin position="18"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="280"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="13">
        <location>
            <begin position="33"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="201"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="201"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="215"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1732970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="371" mass="41535" checksum="9355DE4A85A021AC" modified="2024-05-29" version="1">MKTTAVIAAIVCTSSSAFAPAFTVSRQNTALNLKVGETAPDFALVDQNGKTFKRSAVKKPLVVYFYPADSAHESSVQAKAFQEEIQSIRKEFKADVVGISGQGAESTQKFAQELGLDFSILADERDIVRKEFGASTDIRLLPGRVTYVLDKDGACTKEIDPGCGCIYLSAVVCSRLGADRIGNMAVLKSRYVMVEVEDDDDGEEHEEFVNDDEEALHNRNKGSDTKNDEKTKKQTKRMVRKREIQFIVGPFWPMLLGITYPLIFGVSGLTLFVGLPYRAWYIKLGWTILTVLLIRALFNTGFRDPGILTRHKDPPENENDEEDDAPLRRVGFRWGAEGGPWRWSEQAQTYRPRNSCYDPDTAVVVEEFDHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTV1</accession>
    <name>A0AAD8XTV1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Transmembrane amino acid transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_015665</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000046">
        <property type="protein sequence ID" value="KAK1733622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTV1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF458">
        <property type="entry name" value="SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="138"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="10">
        <location>
            <begin position="62"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="30"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1733622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="163" mass="17984" checksum="DCA1714191733D3B" modified="2024-05-29" version="1" fragment="single">MKNYNSITIIHEDDSLPLFDDNTSLLSPLPNDKTVNYNPHPQDHLAPPFSASQSGDDDSNRPSSLLVGTFNLIATIIGGGVLSLPIAFQKCGIFTTTLFMLTSAYMTYMSLITLCYSSRRCGGSSYGEVVRSAFGERMEEGVSWLLFIFLLFVIADPPRSSWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUV0</accession>
    <name>A0AAD8XUV0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Subtilisin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015135</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUV0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041990851" description="Subtilisin" evidence="2">
        <location>
            <begin position="19"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="244" mass="25366" checksum="00F4EECBC71F8FC4" modified="2024-05-29" version="1">MKLITAIISVFTIAGANGKSSRASTKASKSKSSKARCNDSSLSFSSSPKSGKSHLSLSSKSGKDDRPCLPCSFGDGYLGTNLCGTNVGFCEFSIRDDDDFTVDSCDANDCTPNCVALEPLCDQCALASILGATCPLAEGVCEFTFSAGAEPSCVISDCVIDQDEVSSCGLCSTAPPGAGCPDVEGYCQADTVTDGNGIECTACGDTACPDFTFDECSDPPEGGARRLEMGNKEWIFGINDVFQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVI6</accession>
    <name>A0AAD8XVI6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014522</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVI6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="177" mass="20004" checksum="A92BFE1D107C6BF2" modified="2024-05-29" version="1">MEILKHTVHCRHNQIMNCLQRCQRNRQLHNGFLHLLYRSYLRLLQLTSQCNYLRVTRSPTTAPITPSPTLSPVTTSPATEAPFTLPPVEFVPTDPPVLTAPPVELLTLKPTKSTTKRPTARPTPRPTPRPTPRPATKRPTPKPVVISSDSWFCAKASYTSNWNILLEFGECDKRAFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW21</accession>
    <name>A0AAD8XW21_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AP2/ERF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_014635</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XW21"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00380">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51032">
        <property type="entry name" value="AP2_ERF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="33"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="366"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="416"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1734762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="425" mass="47962" checksum="253F55C2AD729C70" modified="2024-05-29" version="1">MNSQPEQQPTRLGRGPGDRKNDALAPSEEFKQNYVGVTHRKRRGKFQARIYKMNKEYNIGLFDLATDAAFAYDAAYRLFGLKLTQKKVSATTPFNNNDGKSDPFDSDEANFVFNWLTYPDEAMMEVESPERMNFTCPSNYRAKRSEELASRLLAQNGEALKEIGIISEADLVAKVRKEIISISKLAAAICPVQKMFGRRACDLMFDELPEVEVRSRKRSRKPSREYLIKHQYVQQQQQQQQKHQQQQSSNATSNIPLQQMLLQQQMYGQAMMGSRIGYGNMFGSLPMNTMGPPAAASHSLLGYSRERAAMPNDSVSSASSAVNHGIPLASGSSFDPQLLYLMMQHNMPHSNMLSINEQLRNGHRQADMPQANMPNNRPPQVDVPFINEQPRTMPPQPAYESKQSSNNQVLLLPTRKSPPSPETKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW60</accession>
    <name>A0AAD8XW60_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014475</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XW60"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="144" mass="15235" checksum="8B8CCA8F49F0D7BE" modified="2024-05-29" version="1">MEEAVPVKDDDAETESIVSDSSSSDNEEHVETEAIISDSSSSSDYTISKRLTRDKIFSVITPVIPIIIGYGAARIAFALVARVALILSPPAAPIVVAQATGPMSIIKAFVERFLGGPSPAAVVVKDPTLLEKIANMVAKLLKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWC5</accession>
    <name>A0AAD8XWC5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Serine incorporator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_014682</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TDE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWC5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005016">
        <property type="entry name" value="TDE1/TMS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10383">
        <property type="entry name" value="SERINE INCORPORATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10383:SF9">
        <property type="entry name" value="SERINE INCORPORATOR, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03348">
        <property type="entry name" value="Serinc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="210"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="307"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="384"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="422"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1734809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="451" mass="48557" checksum="6E114CBFD4AA2B03" modified="2024-05-29" version="1">MGIISGTLSAIISGVTFCFCSASASLCSAWCGNDKPSTSPPSAKSGRMRSVVLLGFSIIVALSFQYGLGPNVSQLQWSYFIDAWTQSCENDNPELVKVCSGNAGVYRASSAAFFFFVIFGLAALCKPTANRDAWPAKYALYCLLCAGTCFIPNDPIFMPIYLWVARIGSVFFVLLQQIILVDVAYNWNESWIEKADKAEIDEGTGKGKKWLGAILFSCFVLYAGSLVAIILLYVHFGGCQSNDAFISITLVGSIIATIVQLSMSETGSLLTSASMTAYVTYLCGSAVSKNPNAVCNPKLGETSVGNIVVGLMFVFISLMWTGFSYTNDKRLGGSTTAAPEASVEDAEEGKPVGGVVVNENADANETNESSDTTSPKSFNNSWKLNAVMALVCCWYAMTLTGWGSIDKRGDISNPDAGDVSMWMLIVSQWIALLLYLWTLIAPSLFPDRDFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWI0</accession>
    <name>A0AAD8XWI0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014484</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWI0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="256"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="434" mass="47375" checksum="3093E85AA27173A1" modified="2024-05-29" version="1">MLDSLYKQNEHGVLTACGPNCQVAKRRKELQSLGVDPARVQQAMQAMSPTPPPPLTQQNNFTFPQPMPPAMKPPPQQYDQNMNYFPSPNTSGSSGSLNPTAALQSMGSMLKKAPGAAADTLKKAPGVGAVLDSLEPLNYKLDHGLPKPNLIKKFISTGSVFSLRNVCSEDFEMSSDEGKALMEQLNMEVDELLQRKSVGLIEIDSKYAFEDLVFEEDSVDFDADNDFDLPKRELSADMSLMNMSILTINDDEKPPSDSLKGSLKSSLRKKPAFPMRRPFVANDPSTGVQEQSRVSFAAHSVMSLDNESFRNLVTYLQDSDRNLSDVTPDSDRSTSRKMGFPIKKSVVDDYEQGMPTVVGQRSGSEPDEKLSSLTIDEEGGKGDNEFSQLVGEVATNNAAFPLSGRSLMMSAAGVSDMNMSISSDIGDDYLSNNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWP7</accession>
    <name>A0AAD8XWP7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Reverse transcriptase Ty1/copia-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014434</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09272">
        <property type="entry name" value="RNase_HI_RT_Ty1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013103">
        <property type="entry name" value="RVT_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07727">
        <property type="entry name" value="RVT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase Ty1/copia-type" evidence="2">
        <location>
            <begin position="1600"/>
            <end position="1729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="404"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="464"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1250"/>
            <end position="1283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2006" mass="225789" checksum="0C886B65F4BD3040" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXE5</accession>
    <name>A0AAD8XXE5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013993</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXE5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042024034" evidence="2">
        <location>
            <begin position="18"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="169" mass="17296" checksum="F1F6F7618D6F77CF" modified="2024-05-29" version="1">MRTSALIFAAALATASAQDAYNHQLRGDRFLSVSTKAEKAMSVAKAAKSSTKSSKTADAKAEKVSSSKAVKEASMPKEAKAEKEPTAEKETPATSAKAAKVMSVEAKAVKSDDESSSKAAKAVDAKAEKASSVATKAAKTKSEKSVSTKATKETGSVSTKANKGSSMSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXF1</accession>
    <name>A0AAD8XXF1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">U1 zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_013934</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXF1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040023">
        <property type="entry name" value="WBP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13173">
        <property type="entry name" value="WW DOMAIN BINDING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13173:SF10">
        <property type="entry name" value="WW DOMAIN-BINDING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="U1-type" evidence="3">
        <location>
            <begin position="22"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="44"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="328"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="52"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="88"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1735320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="438" mass="48502" checksum="EE54B1F7F756ACF3" modified="2024-05-29" version="1">MSTPYPSQQQKKKGGNEPWRNKERHYCAICNAWMGSDRQSILLHENGKKHREAVEADLKKRRDDKAKKEKDQSDLEKVFAQVNAAAAGSGGGGGGGGGGRKPWEQPTSSYVAAIPSNSLVGSRPPNQHQHQQQQQQHKPKVQNRDIKPAKASSCFTQIPTETKTVPDVNAGHYNIEGTSYLDGSIYAPILEEGMPIQLWVGDPNASDGEKRDLRSFNYWKIALLAKVVKKRKSGNEQEVSSCHVSYLQNSDDDDETLKSNVSPSRIRLVLGSDPLLPSTLEEAHLALLGGEQTIQVDDNNADGIVDENTGLSTWSTTAIRKVSSHYEQNQERKRKREHEKELAEYKEKKEKEIKARMMEEAKYANAHDSALGAYDVWSSATSAVEGKTAAYKGVDINKETKVEVADTAKSLSKGMGSVAFKKKKVKKKSIRRTSADDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXG1</accession>
    <name>A0AAD8XXG1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_014023</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DEAD box helicase family. DEAH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1080:FF:000002">
        <property type="entry name" value="Putative ATP-dependent RNA helicase DHX36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF119">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="499"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="778"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="434"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="690"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="460"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="690"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="711"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1735409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1325" mass="147508" checksum="BA91FCA4464D2845" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXK3</accession>
    <name>A0AAD8XXK3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_013435</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXK3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1735729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="494" mass="54755" checksum="A059E0A0A5A28F0B" modified="2024-05-29" version="1">MYTGPVNAIDVAATIANLPKCEYTPEDCPTAVWWDNPLDENSTRVCMACVVFTEGCGVIGQEDVDFVALNGTDAYSTQCYLGNKDIEEDVKGRVSIMQRAVEKAYEVASQDKDTLKIFVAPEFFWRGPMGSYPFDSIDNPGVEGEFNAINEIGRALEGIIQQEKFSDWMFLFGTIIASKETTLETPEDGDSKRAIEKNGKMFQFLNFAPLYKGFDPAKTNSDGMKFIVPKIEVSTMDFLTEDRAPNPKDEGYYDNVLLNEILDSLQEDGYNLIEQSWFYMNDIAMSVEICVDHADELAKSMLLDPNVTMVPSGGFGEYRELLKPEGAQISLVSSAGMSIKKNSLVLESGGTIFLQDGLGVQLSQEQSCEFDESGGKMEGKWFCSERSYSAHQVYASVGEAEAALRGLFYIRNNTLPEIHLFKPLDIISLGGDDAISDPHIDNNHTIGDMNVTSNDTSSVTNISMKQLLESKRARLFNRLIPYTSVVSALIPSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXP7</accession>
    <name>A0AAD8XXP7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase</fullName>
            <ecNumber evidence="5">2.7.8.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">GlcNAc-1-P transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">N-acetylglucosamine-1-phosphate transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">QTG54_013735</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis, transfering GlcNAc-1-P from cytosolic UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol embedded in the cytoplasmic leaflet of the endoplasmic reticulum membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a di-trans,poly-cis-dolichyl phosphate + UDP-N-acetyl-alpha-D-glucosamine = an N-acetyl-alpha-D-glucosaminyl-diphospho-di-trans,poly-cis-dolichol + UMP</text>
            <dbReference type="Rhea" id="RHEA:13289"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19507"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58427"/>
            <dbReference type="EC" id="2.7.8.15"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="18">
            <dbReference type="Rhea" id="RHEA:13290"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.15" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXP7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003975">
        <property type="term" value="F:UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06855">
        <property type="entry name" value="GT_GPT_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033895">
        <property type="entry name" value="GPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10571">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10571:SF0">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="303"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00029567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00033238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00045078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAK1735572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="436" mass="48369" checksum="A61116EBC9BB6A91" modified="2024-05-29" version="1">MKASLQTIATLPLLPSLWIVCRLISKDLERIQDSISYDEGTATASTVGTQLLLFIALGTLGHVGTNKLIPSIKYYMLKRGITGKDLGKKGTSKENNDIPEALGIVPGAIFLICLMFCLVGFATNHPSKLLDLNSALLSICFMLFLGFTDDVLEWPWRYKLFLPSVASLPLLCCYEGSRSVVVPIPLRFLLMIDGELTTFGKLLCYFVVVDTNADGSIINLGVFYLVYMGLLAVFCTNAINIYAGINGLEVGQSYIIGCAVLFHNLVEIQCDSLSRENHVFSAMIMFSFLGVTLALLRHNWFPASVFVGDTYCYFSGMTFAVVGILGHFSKTLLLFFIPQLLNFLYSIPQLFKLVPCPKHRLPKYNAKTGRMEPSTTTTTTPEGTKERVNMTLINACLQMFGPLSEEVLCVVLLTFQIICCILGLYFRYNVAQLIFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXW7</accession>
    <name>A0AAD8XXW7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NSFL1C family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_013855</name>
        <name evidence="4" type="ORF">QTG54_016754</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000064">
        <property type="protein sequence ID" value="KAK1732542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXW7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061025">
        <property type="term" value="P:membrane fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031468">
        <property type="term" value="P:nuclear membrane reassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01770">
        <property type="entry name" value="UBX_UBXN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.210">
        <property type="entry name" value="SEP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036241">
        <property type="entry name" value="NSFL1C_SEP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012989">
        <property type="entry name" value="SEP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23333:SF20">
        <property type="entry name" value="NSFL1 COFACTOR P47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23333">
        <property type="entry name" value="UBX DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08059">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00553">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102848">
        <property type="entry name" value="NSFL1 (p97 ATPase) cofactor p47, SEP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51399">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEP" evidence="3">
        <location>
            <begin position="93"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="UBX" evidence="2">
        <location>
            <begin position="228"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1732542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1735692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="304" mass="31085" checksum="C63DD00B923861B5" modified="2024-05-29" version="1">MPNIHGLSSIRNNNDRRPPTNNNSDSDSEDNDENNRYVGGVSSRGGGSGLAVLPNHESSGGRNAAAASDSIFNLAEAGGEQAATAGAGGGGGEVRRMITMYRSGFTVDNGPYRRLEDSSNAEFLGSLARGLIPRELREDAEESGGGEVMVGLVDKRGEEYDEDRHGQQQQRGGGGGGFGGGGSGGDGFQSFSGEGQSLVDSSSAAATAPSGGVIDPNNTTSPPPALDESKPSTSIAIRLLNGKRLVVKINLDSPVLELGQHIGSQAGGESYVLTSGYPPAVIEDLSVSVEEAGLKGAQVVLKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYC1</accession>
    <name>A0AAD8XYC1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cystathionine beta-lyase</fullName>
            <ecNumber evidence="5">4.4.1.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_013104</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.13" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1735968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047804">
        <property type="term" value="F:cysteine-S-conjugate beta-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006549">
        <property type="entry name" value="HAD-SF_hydro_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013954">
        <property type="entry name" value="PNK3P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01662">
        <property type="entry name" value="HAD-SF-IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808:SF80">
        <property type="entry name" value="CYSTATHIONINE GAMMA-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="TRANS-SULFURATION ENZYME FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08645">
        <property type="entry name" value="PNK3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="665"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="101"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="102"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="194"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="208"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1735968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1470" mass="163333" checksum="C194FEE658A2D8EF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYC6</accession>
    <name>A0AAD8XYC6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA (cytosine-5-)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_013436</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYC6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044027">
        <property type="term" value="P:negative regulation of gene expression via chromosomal CpG island methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.120.10">
        <property type="entry name" value="DNA Methylase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050390">
        <property type="entry name" value="C5-Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10629">
        <property type="entry name" value="CYTOSINE-SPECIFIC METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10629:SF52">
        <property type="entry name" value="DNA (CYTOSINE-5)-METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="75"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="75"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="112"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="138"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="200"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="211"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1735730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="720" mass="81454" checksum="1BF3ECD2D41E3979" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYI1</accession>
    <name>A0AAD8XYI1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Polyamine aminopropyltransferase</fullName>
            <ecNumber evidence="14">2.5.1.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_013489</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.16" evidence="14"/>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYI1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004014">
        <property type="term" value="F:adenosylmethionine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004766">
        <property type="term" value="F:spermidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.90.10:FF:000025">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.90.10">
        <property type="entry name" value="S-adenosylmethionine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00198">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003826">
        <property type="entry name" value="AdoMetDC_fam_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030373">
        <property type="entry name" value="PABS_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016067">
        <property type="entry name" value="S-AdoMet_deCO2ase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001045">
        <property type="entry name" value="Spermi_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558:SF11">
        <property type="entry name" value="SPERMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558">
        <property type="entry name" value="SPERMIDINE/SPERMINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02675">
        <property type="entry name" value="AdoMet_dc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01564">
        <property type="entry name" value="Spermine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56276">
        <property type="entry name" value="S-adenosylmethionine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01330">
        <property type="entry name" value="PABS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="4" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 11" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0704">Schiff base</keyword>
    <keyword evidence="3 11 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0865">Zymogen</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="PABS" evidence="13">
        <location>
            <begin position="347"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1735783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="744" mass="82495" checksum="03C79E0814660980" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYU5</accession>
    <name>A0AAD8XYU5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WD40 repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_013001</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYU5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037850">
        <property type="entry name" value="RBBP5/Swd1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44040">
        <property type="entry name" value="RETINOBLASTOMA-BINDING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44040:SF1">
        <property type="entry name" value="RETINOBLASTOMA-BINDING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="257"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1736401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="374" mass="41231" checksum="AA37327E39AC475C" modified="2024-05-29" version="1">MRHPTLVLELPRPLGGPTQLHPHHNSTGLACLDDGSLVLFYIPPIAFYETLPASPESSTSAKEAETLDIMKRDESRRVGNIAYLTDPPQSEEDNSSYFITCAAFGKNGEEVYAATKCGSLLVFLTPPSIIQSLQGERRTDINLKVKPSVVFKVPGAAAAWQIVVSRNGKHVLFNSADCALRLYDIDEIFKHDGETNATNIPPRFVFQDTLSRSPWASADFSADGEYVVGGCNSYPQPGDNYNLFMWSTTTGELVDQLKGPHASLYSLSCHPTRSFIAVGSSDGVIDVWGPRVQWTAFAPDFQARQANVLYEEEEDEFDIVVDNNQGNAASEHKEPPEEGIVDIITVEKTAEEVTFPVRVLKLFSEKSKPNKSEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYV4</accession>
    <name>A0AAD8XYV4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">COP9 signalosome complex subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013016</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYV4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050871">
        <property type="entry name" value="26S_Proteasome/COP9_Components"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10678">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="2">
        <location>
            <begin position="336"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="507"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="562" mass="62034" checksum="3944337C00B86780" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYW0</accession>
    <name>A0AAD8XYW0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Timeless family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_013136</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYW0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031298">
        <property type="term" value="C:replication fork protection complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000076">
        <property type="term" value="P:DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043111">
        <property type="term" value="P:replication fork arrest"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044998">
        <property type="entry name" value="Timeless"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006906">
        <property type="entry name" value="Timeless_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22940:SF4">
        <property type="entry name" value="PROTEIN TIMELESS HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22940">
        <property type="entry name" value="TIMEOUT/TIMELESS-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04821">
        <property type="entry name" value="TIMELESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Timeless N-terminal" evidence="5">
        <location>
            <begin position="108"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="481"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="896"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="34"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="900"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="938"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="965"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1009"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1020"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1054"/>
            <end position="1063"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1736000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1083" mass="121860" checksum="82BF5B7E56D0CD7F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZ01</accession>
    <name>A0AAD8XZ01_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cobalamin trafficking protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_013196</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZ01"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009235">
        <property type="term" value="P:cobalamin metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019362">
        <property type="entry name" value="MMADHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13192:SF3">
        <property type="entry name" value="COBALAMIN TRAFFICKING PROTEIN CBLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13192">
        <property type="entry name" value="MY011 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10229">
        <property type="entry name" value="MMADHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1736060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="194" mass="21753" checksum="DEE2ED8B1DE1AB0F" modified="2024-05-29" version="1">MSEQQRHPSDTSSIILPPRLVRNTQSANPDDDLECSLHYLPKPLLREFSHVFNNEHVRFGSNDGNLQLLAIPTNQRAREDLVAVGDHIEAEKDRLLNVFLTFGKCICEQLRSQGYWADYIDPCSGLPMISLNCNKVYSEVDGMECLLNYKAYNAGFCKILTHPKWGSAVYPATIFAYAPVDVAKSLMALFPSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZ19</accession>
    <name>A0AAD8XZ19_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">UDP-glucuronate decarboxylase</fullName>
            <ecNumber evidence="7">4.1.1.35</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_012952</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.35" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZ19"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048040">
        <property type="term" value="F:UDP-glucuronate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044516">
        <property type="entry name" value="UXS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43078:SF6">
        <property type="entry name" value="UDP-GLUCURONIC ACID DECARBOXYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43078">
        <property type="entry name" value="UDP-GLUCURONIC ACID DECARBOXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="4 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="6">
        <location>
            <begin position="66"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1736352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="191" mass="21287" checksum="E3A89D8DBC907875" modified="2024-05-29" version="1">MSDSAKRPAAATNGGISNHDDQETKRARLAQIVQDQQLLASQSIPTPHTPKVIQTVRLPDALRKKILITGGAGFVGSHLTDRLMSEDTRWWYSTTFSPGARLMHDVIQPILLEVDQIYHLACPASPPHYQYNPVKTIKTSTMGTINMLGLAKRVKHVSYWHRQVKSTEIRSPSSTRDILGKCKHIGAKIML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZJ3</accession>
    <name>A0AAD8XZJ3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sulfotransferase domain-containing protein</fullName>
            <ecNumber evidence="2">2.8.2.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012938</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.2.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZJ3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040632">
        <property type="entry name" value="Sulfotransfer_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978:SF4">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17784">
        <property type="entry name" value="Sulfotransfer_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="322"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="390" mass="44260" checksum="16F4C8675F4A72F6" modified="2024-05-29" version="1">MNDQQQQQQPKTKMSTIYLNQNAGGSWSEFFGDIYSGIAVGIGHPKWIVEKAIDQGVKAISSLTGMASSSSSADSSSNNSSIDNGKLDGSLKVIGVGYGRTGTYSLALALDELGFPTLHTQHLYENQKIFTHFVDNIFYKSIQQDEVITPDMYTPDFDLLLDGGFTATMDLPFALYYTQIHEIYPDCKFILTVRENSEVWFRSWDVLTKSITQPAQYGSFFFTHVNRLNYYMRWLFSIVNSDKTYLNAPFPLPPQNKARSISSYEAHNQKVRNSIPSSHLLEYNVREGWEPLCSFLEIPEANCPSTHGIPFPKSNSARAVTWQAYSSFIGPLVLTVFILFSVFSLVFRKVTGMSVISWCLFVKAKFMHWTNESLKERTKRNKNKMGMKMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZL2</accession>
    <name>A0AAD8XZL2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012296</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZL2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1736851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="106" mass="11091" checksum="4C30B8CC3B19D83A" modified="2024-05-29" version="1">MDNIEINQPNPATGGRLEVSLPFNYGTYEVYANGRGVIYLSVGGPNSPYSNPPAMAEFVVTGTSGNGCEITAVDSFLSASSKDGNGNDVGVANQLVAPRFKKIADF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZQ3</accession>
    <name>A0AAD8XZQ3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013013</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZQ3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041935151" evidence="2">
        <location>
            <begin position="21"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="153" mass="17116" checksum="45F7BA3C7E4BB84D" modified="2024-05-29" version="1">MIPTLFILLFIAPFVHFVDATAAATSVGGRAAHDVDSSYQDEGTRQFIEKDYLSLMTNYVNDQRYLRGRKLQENIDYQKQPYYQSQQQTHGASRAQAIILTIVVTLTIALAVYAAFLYREFAAVTLYNVLGYRLFGDSDVQGGSGEQEGVEIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0H1</accession>
    <name>A0AAD8Y0H1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012817</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0H1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="151" mass="17606" checksum="8A06A9F5D855D460" modified="2024-05-29" version="1">MIDETDKLEILKEEEDERQQRIDSFKNYDFTTIPTSTSEESLSEKQKNEEEEVVLRRGHDSTSDQGTFISHEDDYFQAIPPPTKKRKAMMVAQCEILEDTDDGTIHKEFSGYDGGATMETYEEYQETTFSAEEVNYTTEFTDYTYDATCMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y110</accession>
    <name>A0AAD8Y110_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Frataxin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_012492</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the frataxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1737047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y110"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004322">
        <property type="term" value="F:ferroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034986">
        <property type="term" value="F:iron chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.10">
        <property type="entry name" value="Frataxin/CyaY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002908">
        <property type="entry name" value="Frataxin/CyaY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036524">
        <property type="entry name" value="Frataxin/CyaY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020895">
        <property type="entry name" value="Frataxin_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16821">
        <property type="entry name" value="FRATAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16821:SF2">
        <property type="entry name" value="FRATAXIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01491">
        <property type="entry name" value="Frataxin_Cyay"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01219">
        <property type="entry name" value="Frataxin_Cyay"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55387">
        <property type="entry name" value="Frataxin/Nqo15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01344">
        <property type="entry name" value="FRATAXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50810">
        <property type="entry name" value="FRATAXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0410">Iron transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1737047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="241" mass="27663" checksum="D8454510F2C7122E" modified="2024-05-29" version="1">MFNCLGRRMAPQFCRQQHSSIKCGVLKSCSAYYQPHQVETGMQSRKLSHAKGACSTLPRTLFNNTSRSEHYIQQHRYTTASLRCNLNKPGPNNYVMCCQIRLFQNVSQYHNVADDTLHTIQDAVEDLIEDNFDTDTNNSDDDTLPEVNYASGVLTMSLPPHGTWVINKQTPNQQLWWSSPISGPRRYEYVEERERWVYTRVIEEGDGKECAEVAENDDDTLGSILTQELKELYGWDLDVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1B1</accession>
    <name>A0AAD8Y1B1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">RNase Z family protein</fullName>
            <ecNumber evidence="9">3.1.26.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_011868</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.11" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1B1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042781">
        <property type="term" value="F:3'-tRNA processing endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01818">
        <property type="entry name" value="RNase_Z_BN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013471">
        <property type="entry name" value="RNase_Z/BN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46018">
        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46018:SF2">
        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23023">
        <property type="entry name" value="Anti-Pycsar_Apyc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1737582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="557" mass="61639" checksum="50D33FA0EB75D5C7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y243</accession>
    <name>A0AAD8Y243_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Beta-glucan synthesis-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_011732</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SKN1/KRE6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y243"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015926">
        <property type="term" value="F:glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006078">
        <property type="term" value="P:(1-&gt;6)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005629">
        <property type="entry name" value="Skn1/Kre6/Sbg1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31361">
        <property type="entry name" value="BETA-GLUCAN SYNTHESIS-ASSOCIATED PROTEIN KRE6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31361:SF1">
        <property type="entry name" value="BETA-GLUCAN SYNTHESIS-ASSOCIATED PROTEIN KRE6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03935">
        <property type="entry name" value="SKN1_KRE6_Sbg1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042187385" evidence="12">
        <location>
            <begin position="38"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="652"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="13">
        <location>
            <begin position="98"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="54"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1737446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="694" mass="77917" checksum="9216D8C9DD6091A8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2C5</accession>
    <name>A0AAD8Y2C5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">subtilisin</fullName>
            <ecNumber evidence="7">3.4.21.62</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_011023</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides.</text>
            <dbReference type="EC" id="3.4.21.62"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.62" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07477">
        <property type="entry name" value="Peptidases_S8_Subtilisin_subset"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001673">
        <property type="entry name" value="S_mold_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034202">
        <property type="entry name" value="Subtilisin_Carlsberg-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00526">
        <property type="entry name" value="Dicty_CTDC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 8" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0720">Serine protease</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042049457" description="subtilisin" evidence="10">
        <location>
            <begin position="20"/>
            <end position="1387"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="11">
        <location>
            <begin position="256"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="93"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="904"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1148"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1345"/>
            <end position="1387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="100"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="904"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="936"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="946"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="1364"/>
            <end position="1377"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="304"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1738354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1387" mass="146186" checksum="F5B09FF743055204" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2H0</accession>
    <name>A0AAD8Y2H0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Leucine-rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011253</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2H0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="322" mass="36233" checksum="8F1B087160279E24" modified="2024-05-29" version="1">MANNIDGDDVFLYTGEGQEVPEDVTHVRIGESVTFIPSEAFYWRTFLVSVEMHNGVEQILAHAFWMCTSLTSINLSGVEIIDESAFKGCKNLADVDFGEKLDVIGREAFKSCHSLKNIVLKNVRAIAFGAFSSCRNLADVECGEKLMRIEGNAFNQCRSLRRIVIPLKVDMVGFYDRAFNSDGLSKIDLVGGIHKTISSLHLDSWKSQMNQQINRVNLTLPTVPAGSKTTFIQDWIVSTHRRFNHCKKEHYKLLKEATTLLELALWKSMLEINADSSFEVNPKKKAKIDDMTSRTKQRIAAGAAMSIVIKNVLPFLRLEELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2J1</accession>
    <name>A0AAD8Y2J1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011617</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2J1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="239" mass="26020" checksum="F9009568394E2D94" modified="2024-05-29" version="1">MLNSLSVDDHQQQQCRKMKTTASALAILSYTSIISSATASTPNHLRGGIDNDNGGASAQLPCTYLTKPVDYDVCMNNNVPGCQDETNRAVNQCYNVGSDWYVCSPASQCNATTTTSTIVPNNTKRQVDNDECKANTGAECINRDVCWDHYHNGQHYYYCEEPREVAPTTPPGPTCVHHNQECNPDPNDELNQCCGTLTCASVDGNVSESHRGAFGGIEYACFSHRESEGGDEGDYLADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2U4</accession>
    <name>A0AAD8Y2U4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011563</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2U4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="173" mass="18933" checksum="5592520A2100F6DF" modified="2024-05-29" version="1">MAERQQSQMSNLEETSNHHEDGFDLENPDRITDASEHEHENDEEYADDDTYTKRSFGCRWITAAIVVVTILVIFLSSGTLGVAAKNQDVDKEDAATVGGGGDLGKKTSLGGEGNTEVVKIEKDTVEQKAEKAQKTEKSKKSKKSKKGGRSLLGQLSEMAMMEAAFMMVRDDDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3E5</accession>
    <name>A0AAD8Y3E5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_010252</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3E5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1738936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="249" mass="28031" checksum="2B27E75B146F0C6F" modified="2024-05-29" version="1">MILVNLATHCKSIATEHKRTTIIAMKTPKKPRDNRLRECFQITTIEGVGERVICLHCSDYDRTLTKFNATKARNHLTDQCVGVNEEMREMFRQSTQAAKKQKTEMGLTHATMDDIITMPALPSTSLAMTTKEKKRKTISNRQSLVYLSFYLESTSIIVTAPVEKGELILHLAFPRNQLNLKFNAETNLEGAAVVIDGFMNKNEGSWSASMRKVGAAENLGTAGDYCQWQLESVSRMDQVKQILKSLVMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3T0</accession>
    <name>A0AAD8Y3T0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3T0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="229" mass="25500" checksum="01154705D8989ECA" modified="2024-05-29" version="1">MLTPDQLLLTPNKLLLTLDEMTTTKASAKKRAAMSKQSPYSKSVVKAGKTVPRQKHCSAKEVALVAKSMQGKQTPTKAARLDAKARARAWAKRELDQKRKGSQSQSRPQVSAAASGRSVSAKDEEDVVSDLTESESMNKEMVKALDQIGKSDNRFIVDDISEDVFYDALEFLEEEESREDVVVEDASDDDDEEIRNLRSTINNQMPTKYWMEPVGVLYSDVVGMKKPDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3V4</accession>
    <name>A0AAD8Y3V4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Mitochondrial carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_010607</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3V4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051028">
        <property type="entry name" value="Mito_Solute_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45678:SF9">
        <property type="entry name" value="CALCIUM-BINDING MITOCHONDRIAL CARRIER PROTEIN ARALAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45678">
        <property type="entry name" value="MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="82"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="172"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="260"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1738577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="348" mass="38042" checksum="F2059330E2B93CCF" modified="2024-05-29" version="1">MAMLLKYRESQKKAASLLPTSSDVMPFLPPSDRPKVHSPVNISRRFTSLEVLPAPEPEKRNVIGQQKHTVEIRSGGVIAFRVPLYQKMLVGGISGVIGLSTVFPIDLIKTRLQISDVGLSSVCRDVFAKHGISGFYRGLGATAIMVFPEKACKLGVNDYLRDVFCNYDRNKETVVQQVMAGALTGVIQVAVTNPMEIMKIRLQTAESATVSPLQALGELGWKGLYNGSGVTLLRDVPYNVIFFLSYIEIKRALTSPEGEVSRARILGSGVAAGMLAAFFGTPMDVVKSRIQMRNSPYTNGAIDCAKRLYAEGGYGIFFRGAFPRMAVQGPLYGIALLFFELQSQYLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y546</accession>
    <name>A0AAD8Y546_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nitronate monooxygenase</fullName>
            <ecNumber evidence="4">1.13.12.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_009643</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.12.16" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y546"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332:SF20">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1739884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="367" mass="39962" checksum="47FCFA8054A8DFD5" modified="2024-05-29" version="1">MNKEQAPPILLLPINLFGSNKTMGSSNNKSRMWKTPFTVAFRCRLPIISAPMAGVSGGLLAARVCKAGGLGMIAAGHFQDISKLEKEIQIFQEEMKNIPATGTTTDDRSHSQHQSADLSIGFIGFSALSTPNGWKDYEYILKHHRPKAVQFFAPSIIHQPNDGLSNVQLAHEYNTQFIAQVGSISEAKEAIRHKVDAIICQGSEAGGHGLRRELGSSTMALASQVSKMTSIPVLAAGGIVNGKHLASALCVCDGASMGTRFWASKESTGNPKLQQELIKDNSCDDVVRTTMFDQIQNELSSIMWPHPYHSVGALHNQTSLEWEGKTAQELQNAIDKTELLDEYKSAQKASDPCVGWAKSIISRKPMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y597</accession>
    <name>A0AAD8Y597_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009903</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y597"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042233324" evidence="1">
        <location>
            <begin position="19"/>
            <end position="908"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="908" mass="99237" checksum="90469B76AC6DB012" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5B8</accession>
    <name>A0AAD8Y5B8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">VWA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_009642</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5B8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005891">
        <property type="term" value="C:voltage-gated calcium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005245">
        <property type="term" value="F:voltage-gated calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051173">
        <property type="entry name" value="Ca_channel_alpha-2/delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10166:SF37">
        <property type="entry name" value="STOLID, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10166">
        <property type="entry name" value="VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042121133" evidence="2">
        <location>
            <begin position="21"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="570"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="3">
        <location>
            <begin position="231"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1739883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="669" mass="73211" checksum="F893D8DE92F14D58" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y666</accession>
    <name>A0AAD8Y666_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009187</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y666"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042210169" evidence="2">
        <location>
            <begin position="20"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="420" mass="42880" checksum="673753AD361A02CA" modified="2024-05-29" version="1">MKIQSSLLFLAAMVGSATAANKRKRVFKIYSREEIHAAEATRSLQGGGGKNQGGNDKDPAPEVVPASVRIPTDASIETIITSAPTAMSMMTKCAFCHGVIMPNPEYDLGVQSQTCGTVKMAVSTMDATNANCALAKQAEAICCPPVVETTTTTSATTTAAMMSMPTTTEAADIVETETTTTATEAAIVPVAPTPLPPTPPSPTPEGAPSGAMTMETTLAALTVVAGAMMLIQSSLLVCAAMVGSATAANKQIEAAEATRSLQGGDDKTDETAPAVMSMSMTLSPSGSPTDASIETIITSAPTAMSMMTNDQTCGSVKAIADGMDVTDNWCVQLQRAEEYCCPPVVETTTSATVTMPLSTTTEAAVVETETTTTATTTTTEAASVPTATPPAQETLGAPSGAMIMKTTLAAVVVVGAMMFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7I3</accession>
    <name>A0AAD8Y7I3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008194</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7I3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="98"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="138" mass="15879" checksum="ED72A75EB1799F7A" modified="2024-05-29" version="1">MLENNLTACCGTRLDHGIISFDDCELGIQDWTCNECAKYYCCECIDGDDNSLLRFCHTCERKYCTTCVAMFAMTAFGRNVVNAARDGSTCKECVNMISSLLLKENEKKQREIENLQYKNEELRTRLRDIRAMTYGVHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7L7</accession>
    <name>A0AAD8Y7L7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peroxisome biogenesis factor 19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007754</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7L7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033328">
        <property type="term" value="F:peroxisome membrane targeting sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045046">
        <property type="term" value="P:protein import into peroxisome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.900">
        <property type="entry name" value="Pex19, mPTS binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006708">
        <property type="entry name" value="Pex19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038322">
        <property type="entry name" value="Pex19_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12774">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12774:SF2">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04614">
        <property type="entry name" value="Pex19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="519"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="561" mass="61175" checksum="58D499ACA8A3470B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y840</accession>
    <name>A0AAD8Y840_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase M10 metallopeptidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y840"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="288" mass="32470" checksum="2C008216EED1E7D9" modified="2024-05-29" version="1">MGKIISGITSLLLLGGIGIALWYFLGKPENLSEAKDGLGDAYNKTKDQIDKFDFGDVLEDLSDLDWGQFFNDDPFAGNSTVTLWDEQFIERDDGGLQLTLVNSLSADWQEEFEVAVADWSMSDALTLDVVVEPVDDAWDNDKKCKRQDDKMVVCNGNFGDTGWVGINENEVLRGRIISSVAKMNEYYLNKADFDHRRFTMCHEIGHGFGLPHTDENPYNKNLNDCLDYTDNPSSNVLPGEVNMIKLQEVYLATEREKRLLRRVENKDGSVTETIGWMINEDEAEASSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8C4</accession>
    <name>A0AAD8Y8C4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008315</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8C4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1741063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="279" mass="30775" checksum="626808F1246D3F6D" modified="2024-05-29" version="1">MVATYDDIDLSNMVEACLDFFHQGTAHQYLRIMMDRTLLLEMLLTTNKFGTLQSYLAEFAADFARRAKSFSRSESEAKLKGEGKDILIQATAFVTEYGTQNDWDEFGKYTIMSVDFYSAFTNAVLDVSGQGLLRDVLNKCLVQYSITGSDTSVSSWTVKKANEPTILILPTPSLHVQKVLELCPGIVQAVDKDKRLPLHYAAASANASFEVFMKIFEANKDAASIRDPATGLFPFQLAASNGNYAASFSLLLANPNIVSSAVDDDDAPDVSDRKRKRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8I6</accession>
    <name>A0AAD8Y8I6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aspartate aminotransferase</fullName>
            <ecNumber evidence="8">2.6.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_007196</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.1" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8I6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004069">
        <property type="term" value="F:L-aspartate:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050596">
        <property type="entry name" value="AspAT/PAT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46383">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46383:SF1">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="7">
        <location>
            <begin position="83"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1741623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="493" mass="55605" checksum="D2EE5F546CB550B4" modified="2024-05-29" version="1">MPRGADRRNTAHNIFLKFHRHTAKSMKDLAIEEESEDEDQEFESTPQAEPNSPFEMFHHVMKTGVIYASSRAAKHGFSMLSEDWANMGQGAPETGPLPGAPTRDFHMNIQDAELEYAPTTGDTELRVKVAEYYNHLYRQEKESKYTYENVCIVPGGRAGLTRVMAALGNIQVGYFTPDYTAYQQALGLFMRISPSPVLHRNVHEALLPSEDFAFEAGGRGLGAMLLSNPANPTGQSLEGDELDAYVKIARDLNCCLLMDEFYSHYYYDGENVSPEDGGADDDSNWPKTVSSAKYIDDVNEDPVVIVNGLTKNWRCPGFRVCWLVAPKPIVEMLGSAGSFLDGGANAPLQKLALPLMDLDFIRRDTWALQRHFKMKRDFLLTELPKIGITVKWEPTATFYIWADLSALPAPINDCLCFLEECVKHNVICVPGVFFDINPREIRHLKQSKCINFVRFSYGPPMRNLTKGVEEMGKMISYWRKNQMTSSDYARTSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8X7</accession>
    <name>A0AAD8Y8X7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_008457</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the citrate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8X7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046912">
        <property type="term" value="F:acyltransferase activity, acyl groups converted into alkyl on transfer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006101">
        <property type="term" value="P:citrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.230.10:FF:000001">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.580.10:FF:000001">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="entry name" value="Citrate Synthase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="entry name" value="Cytochrome P450-Terp, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010109">
        <property type="entry name" value="Citrate_synthase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01793">
        <property type="entry name" value="cit_synth_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007128">
        <property type="entry name" value="PRK09569.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739">
        <property type="entry name" value="CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739:SF8">
        <property type="entry name" value="CITRATE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 5" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="3">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="347"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR610109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1741205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="465" mass="51583" checksum="B2BC27A9FE415D72" modified="2024-05-29" version="1">MNALSTATKFLTRRATTSGTAIRSVTTLQETLASQLPAKQTQLATLKKEHGSKVIGQVTIDQLIGGARGVKCMLWETSNLDPEEGIRFRGLTIPECQQVLPTYSGKAGDGEPLLESLIWLLLTSEVPTKEQVDTLTAELHQRASKLPSHVIPLINSLPKDMHPMTQFSIGLNAAQTGSEFAKAYANGVPKNEYHKYALEDILNVFAIIPEIAAQIYRNVYFDGVVTKDQSLDYSGNFCRMLGYDDPSFDELMRLYLCIHTDHEGGNASAHTTHLVGSTLSDPYLSYAAGLNALAGPLHGLANQEVLRWIQALQAKFEAEGKEVNAETITEFAWETLNAKKVIPGYGHAVLRKTDPRYSCQREFGLKHMPDDPLFKIVETIYSVMPGILTEHGKVANPYPNVDSHSGVLLWHYGFTQYQYYTVLFGVSRAVGGLCQLYWDRALGLPLERPKSHTPEWLETFAKNNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9Q6</accession>
    <name>A0AAD8Y9Q6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_008302</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9Q6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF82">
        <property type="entry name" value="KP78A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1741050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="212" mass="24150" checksum="5C01FD107D3DF029" modified="2024-05-29" version="1">MSWEHIQASKGRMQEDFVKEIAALQYLSKFINGTMNNPRNVSQQIMANQSEVFIVMPYCANGDILVQVSESTLLNPYQGTPCLTEAAAKYWFRQMLTGLRTLQNARLGWHETFNIEANCVWKSALYVTGVATHQPFDGHAVDIYSTGTVLLFMLTGLRLTGPITQDRMFDSMEPSQYGLSVDAMDLLRKMFRLNPVDRLTLDEILTHRFLQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAQ9</accession>
    <name>A0AAD8YAQ9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AP2/ERF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_006264</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAQ9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32467">
        <property type="entry name" value="AP2-LIKE ETHYLENE-RESPONSIVE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32467:SF90">
        <property type="entry name" value="AP2-LIKE ETHYLENE-RESPONSIVE TRANSCRIPTION FACTOR AIL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51032">
        <property type="entry name" value="AP2_ERF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="138"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="222"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="81"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1742667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="280" mass="31162" checksum="C669C1DD6483E7D2" modified="2024-05-29" version="1">MVTRTFVRVSTTPSEAAAPSTAVVDSSINASAPSKQILKQSQLHSCKHHSCSDRAKHPVDATAAAEEGLCDRHSTLVNKAEGGDKKRALPSEESISSEEIKKRRRNCHQKSVVIDLSDVPPQSPIPKSRGRIKEGASKYAGVHFHKEIKKWQARILVDGKRRSIGYYESEEDAAVDYARAIFKYKARKLNSFVVDLTGVPPKSPIPKSAGRIKEGMKEGASKYAGVYFKKEIQKWQARILVDGKQRSIGYYESEEDAAVDYARAIFKYKGEHINSRFSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCJ8</accession>
    <name>A0AAD8YCJ8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005528</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCJ8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="165" mass="19021" checksum="593ED01EA5511E7E" modified="2024-05-29" version="1">MEEVEEATPTLNLEAQNNRSDVFVAARLRECRIVALSCEMRLRQVNYILFTKGLLTVFASLAGVSLFADKRYKAYFDVATVLVAIGSAMHTAGGYDKYQAELREKRKSYHYLVRRYEAFQHGVYLVDREQEMEKLELDFQNKLRRAPLISGTPEFGTRLQPRSTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCQ9</accession>
    <name>A0AAD8YCQ9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Tom70 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_005800</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the Tom70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCQ9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030943">
        <property type="term" value="F:mitochondrion targeting sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="SecYEG/CpoB_TPR"/>
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    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46208">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46208:SF1">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09976">
        <property type="entry name" value="TPR_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 10" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="337"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="Ancillary SecYEG translocon subunit/Cell division coordinator CpoB TPR" evidence="13">
        <location>
            <begin position="443"/>
            <end position="569"/>
        </location>
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    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="531"/>
            <end position="564"/>
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    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="32"/>
            <end position="99"/>
        </location>
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        <location>
            <begin position="67"/>
            <end position="90"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF09976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1743179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="674" mass="74253" checksum="51DBB73BAAA64672" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCX2</accession>
    <name>A0AAD8YCX2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TATA element modulatory factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005851</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
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            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Growth_transcription_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46515:SF1">
        <property type="entry name" value="TATA ELEMENT MODULATORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46515">
        <property type="entry name" value="TATA ELEMENT MODULATORY FACTOR TMF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="25"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="116"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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            <end position="751"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="763"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="884"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="793"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="116"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="161"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="176"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="187"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="233"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="343"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="375"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="397"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="420"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="470"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="499"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="705"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="765"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="887"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="911" mass="102534" checksum="380463DD5C0FD5A2" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD21</accession>
    <name>A0AAD8YD21_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">glutamate synthase (ferredoxin)</fullName>
            <ecNumber evidence="15">1.4.7.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">QTG54_004764</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="14">Amino-acid biosynthesis; L-glutamate biosynthesis via GLT pathway; L-glutamate from 2-oxoglutarate and L-glutamine (ferredoxin route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.7.1" evidence="15"/>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD21"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016041">
        <property type="term" value="F:glutamate synthase (ferredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019676">
        <property type="term" value="P:ammonia assimilation cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00713">
        <property type="entry name" value="GltS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050711">
        <property type="entry name" value="ET-N_metabolism_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006982">
        <property type="entry name" value="Glu_synth_centr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11938">
        <property type="entry name" value="FAD NADPH DEHYDROGENASE/OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11938:SF133">
        <property type="entry name" value="GLUTAMATE SYNTHASE (NADH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00310">
        <property type="entry name" value="GATase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04898">
        <property type="entry name" value="Glu_syn_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="12" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="8" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="16">
        <location>
            <begin position="71"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00037928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00039085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1744231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1077" mass="118293" checksum="4B7589538CCA334C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDK7</accession>
    <name>A0AAD8YDK7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminotransferase, class IV</fullName>
            <ecNumber evidence="2">2.6.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006133</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDK7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47703">
        <property type="entry name" value="D-AMINOACID AMINOTRANSFERASE-LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47703:SF2">
        <property type="entry name" value="D-AMINOACID AMINOTRANSFERASE-LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="557" mass="62700" checksum="FFB65FA82942009E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YE51</accession>
    <name>A0AAD8YE51_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005496</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YE51"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="92" mass="10712" checksum="4F3A969D4769C7F0" modified="2024-05-29" version="1">MRIRLSGKETKYKKQKGEETPEYDDKHNSCPVGLFSLLTMKLPCYKQFDEEEQKKKIRTLGEVLGFTSYITRYSWSLDKLFCRTGGTHPPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YF04</accession>
    <name>A0AAD8YF04_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DUF1995 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_005347</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YF04"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018962">
        <property type="entry name" value="DUF1995"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037359">
        <property type="entry name" value="NST/OST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10605:SF56">
        <property type="entry name" value="BIFUNCTIONAL HEPARAN SULFATE N-DEACETYLASE_N-SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10605">
        <property type="entry name" value="HEPARAN SULFATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09353">
        <property type="entry name" value="DUF1995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sulfotransferase" evidence="5">
        <location>
            <begin position="7"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1995" evidence="6">
        <location>
            <begin position="311"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="active site" description="For sulfotransferase activity" evidence="3">
        <location>
            <position position="14"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>3'-phosphoadenylyl sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>3'-phosphoadenylyl sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR637359-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR637359-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF09353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1743750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="774" mass="87348" checksum="BBEDECD334532DEC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YF78</accession>
    <name>A0AAD8YF78_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003328</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YF78"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="830"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="28"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="971" mass="110182" checksum="F21BAD801948D128" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGZ4</accession>
    <name>A0AAD8YGZ4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_002715</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGZ4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="480"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="775"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="811"/>
            <end position="843"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1746108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="876" mass="97856" checksum="A650C2CE6DB6924D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YH46</accession>
    <name>A0AAD8YH46_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sulfatase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YH46"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015024">
        <property type="term" value="F:glucuronate-2-sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051849">
        <property type="entry name" value="GAG-degrading_sulfatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46615">
        <property type="entry name" value="ARYLSULFATASE K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46615:SF1">
        <property type="entry name" value="ARYLSULFATASE K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase N-terminal" evidence="1">
        <location>
            <begin position="3"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="167" mass="18643" checksum="79C2EC3D36CF3817" modified="2024-05-29" version="1">MEATGQMENTIIVRLADHGELGLSHAMREKRMQCYEETMGIPLVINYPSKWFNGGDTNSPKSTTQVFSNLVSSIDILPTIADLAGVDCSQYQYRGTSLVPFLQNESTTCKSEEEILFTFDEQLAQAVSQGIFDAYALMISNIQFTSQAMARYGVRNVQLARRPTRNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHA8</accession>
    <name>A0AAD8YHA8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_003922</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHA8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1745998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="265" mass="30791" checksum="C8652F645BBF1AD9" modified="2024-05-29" version="1">MTAKKGCVNINSSTHPHVYELFDFVKFHHMWREQSQALDNRWLYLPESTYEDLCWIAIGFALIAMTHLPEGETMAQSRGGSDHLEESFCMAKNKNSCATALDTNAIMARNCSASFMSLYRSRKSNGEGRKVFSVNEVQSFKVRRPKIEHTARKPAAAVVVNRVVPQPQPQPPRQLPQEVQELVDKVASSYYHGQQIANVLFQAFNPVRVRMAEPEDTRNFEEVAYQSYTEFFQDDSWFRNPNYSLDYRQQFLWELPQLTRYIMDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHD7</accession>
    <name>A0AAD8YHD7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHD7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="887" mass="101726" checksum="484D496892276F0F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHI3</accession>
    <name>A0AAD8YHI3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003296</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHI3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042038808" evidence="2">
        <location>
            <begin position="21"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="294" mass="32330" checksum="6CEC3340BEA3F494" modified="2024-05-29" version="1">MKISSALLLWTTAIMGSSHAFVSTSKTAATKKLVQSSNYLPSPTANGGTYTTSLKRQLHSQPSPTTTTTSVEDEELTPETIAEMIEVSFIQSCLQLSQGYVDVLKLFIVAVKTGYETNLSLEELHDLVTDCPVNTAGRDLMKEELALRREWMMMVYEMMKVLKVYENQAAASDDDDAPQTDNDSQTRVAQVVESMLNLQTVLKEEDEQSGGQQDVNVALTTLSVESAMEKLPSLTQLLDSIENPVDKAFLTNDVRVALLTFKVLDEERVCLEDAKGSRSVAKGETIPRPPIKGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YID9</accession>
    <name>A0AAD8YID9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">40S ribosome biogenesis protein, Bms1/Tsr1 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_002473</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. TSR1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YID9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000479">
        <property type="term" value="P:endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012948">
        <property type="entry name" value="AARP2CN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039761">
        <property type="entry name" value="Bms1/Tsr1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007034">
        <property type="entry name" value="BMS1_TSR1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858:SF1">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN TSR1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08142">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04950">
        <property type="entry name" value="RIBIOP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00785">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01362">
        <property type="entry name" value="DUF663"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AARP2CN" evidence="3">
        <location>
            <begin position="371"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosome biogenesis protein BMS1/TSR1 C-terminal" evidence="4">
        <location>
            <begin position="629"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="477"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="532"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="615"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="483"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="532"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1747129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="953" mass="102921" checksum="ADD97C64A5B08A48" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKE8</accession>
    <name>A0AAD8YKE8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_002075</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKE8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF6">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="395"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="429"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="98"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1746731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="461" mass="50086" checksum="F69110F56B720AC7" modified="2024-05-29" version="1">MRVLCLHPSTSSAHQLHSSLSSLEDRLWTKHGIELVFIDAPLLDVQIGDSLGEKGGGLTALHLDGEEGNEGEGAPAVSRRWYVEEAVDGRRSALPPSSDDSAGTTPQEVNSKNSAAVKYSGLDASLLHLSQIWSRGGANHNNTNTDNSNGGGIEQCLPFQGILGIHQGADVAAMLPLLNTANAVYNDEDIEEEHKENKSIFEGLQFVIMVDGRDIMCQDQHEENMGNDGSVHGMNKENDENDNATLVEEEDWYVGPNGISSLHVIAETCNNDNNASATNKRNSELLAKRYGPNATIQYYKPSKKSSSSSQSNKNNLQQQAYNHNQATSPSLHNILGKYLVHQKNTFHSNPQKRKLLQLQHQLCHVEQLASVMITEEVRKNPPKCLMAMIGPAAAASEMENTEDENDENNKNSADDENSAVKAVVPKTVGAWQGPGRVPGEQGGGAHAQSLSCCDRRNVVIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKQ0</accession>
    <name>A0AAD8YKQ0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RNA exonuclease 4</fullName>
            <ecNumber evidence="1">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_001282</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKQ0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="193" mass="22180" checksum="707EF7B00ABBB578" modified="2024-05-29" version="1">MQEVPDLEDSSKSSLRPRKLKELVKDRLGNDIQELGKAHDPVEDALSALRLYKTERLQWEQFVVQKVAAAKVQEPRPYALEIMPPAPIPYNQNHLGSPNNMNMPMNMNMGMHSPSHSPNRNRYQSRNFQPRNRAYSAQHHQQQNYGAERCIGATIKAGQTQILLEGRFPFAFGRQKYYGVHSIIKETKKILNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMJ0</accession>
    <name>A0AAD8YMJ0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_000666</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMJ0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051068">
        <property type="entry name" value="MFS_Domain-Containing_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23510">
        <property type="entry name" value="INNER MEMBRANE TRANSPORT PROTEIN YAJR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23510:SF64">
        <property type="entry name" value="INNER MEMBRANE TRANSPORT PROTEIN YAJR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="445"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="478"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="510"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="571"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="625"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="715"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="746"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="807"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="847"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="884"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="6">
        <location>
            <begin position="2"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1748727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="911" mass="100737" checksum="1E906B71C6D322F6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMV9</accession>
    <name>A0AAD8YMV9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Mitochondrial carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_000862</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMV9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990547">
        <property type="term" value="P:mitochondrial phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000310">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044677">
        <property type="entry name" value="SLC25A3/Pic2/Mir1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45671:SF12">
        <property type="entry name" value="MITOCHONDRIAL PHOSPHATE CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45671">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25 (MITOCHONDRIAL CARRIER PHOSPHATE CARRIER), MEMBER 3, LIKE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041979945" evidence="13">
        <location>
            <begin position="22"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="35"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="133"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="247"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1748923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="351" mass="36684" checksum="7BEA941CC32FAD44" modified="2024-05-29" version="1">MARGLLRLLLAIATVASPASAASASGAAGVVIDPRFFIAGGTCAAISHGITTPIDVVKTRMQSNPEKYKSLLPATALIIKEEGAQALTKGLVPTLVGYGIEGALKFGIYEVSKPMAVLAFQKLNNKLNRSGGTGPLPFLLASIMAGAVASLVLVPMESTRIRMVTDASFEGIGLLRGLGKLVEEAGLVQTLTVGLGAMLAKQVPYTFGKQVSFDVVAKFLYGILNNPSQSTANLAETISKSVSPEFIKWTVSVLSAMFASVMACLMSQPGDVILTETYKGGEGDDTKKRGLAEVSSSIFARNSEDGVALALTGFFTGLQARFVHVGMIITSQLVIYDLVKQLLGLPATGSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPJ8</accession>
    <name>A0AAD8YPJ8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000986</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPJ8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1749047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="135" mass="14534" checksum="E4A18D684AC4EE66" modified="2024-05-29" version="1">MTPSASTAAINVSMKDGDDDVTSEEVGNSQSISNGSMPSLLMSEGVVSPVCEEDLIMNDEQAEDTDSGTPQQLDNSQTNAEMGIPSMNSSSDWEIERRGDFEDTFPPPNTAAPLPTKQTTQWLRSSSPSLFQNEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPL4</accession>
    <name>A0AAD8YPL4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000909</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPL4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="558" mass="62620" checksum="F60D12CDC12C7357" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4P3</accession>
    <name>A0AAD9D4P3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016537</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000057">
        <property type="protein sequence ID" value="KAK1732825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4P3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="178" mass="18154" checksum="11BC57CA1D6D4174" modified="2024-05-29" version="1">MGYYVVVANGLIQSDQCALLPSVITDVCECIPAKAPTPSPVAATDPPTSSPTKNPTLAPIASTDPPTSSPTKSPTLAPIASTDPPSSSPTKTPTLSPVPDPTKEPTFAPITPTPTKAKMPTSFPTTFGKAAKSKSSKGARMAETSGVGCSRASSSNCDGLLMALPFLVCFVAEVLHLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4Q5</accession>
    <name>A0AAD9D4Q5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_015219</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1733961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4Q5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="entry name" value="Integrin alpha, N-terminal"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013519">
        <property type="entry name" value="Int_alpha_beta-p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36220:SF1">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX COMPONENT C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36220">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14312">
        <property type="entry name" value="FG-GAP_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="Integrin alpha N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51470">
        <property type="entry name" value="FG_GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="repeat" description="FG-GAP" evidence="4">
        <location>
            <begin position="870"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="65"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="245"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="372"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="981"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1041"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="77"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="384"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="421"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="442"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="462"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="487"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="534"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="982"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1041"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1058"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1073"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1100"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1126"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1156"/>
            <end position="1168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1733961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1168" mass="123712" checksum="AC779593A56A9907" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5Z1</accession>
    <name>A0AAD9D5Z1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014123</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5Z1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1735057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="263" mass="28777" checksum="A47334FBF9BFF37D" modified="2024-05-29" version="1">MDGLMLEDMFEKKINQVFRFPLLVTTGLRINIVYLGQHVCTILHHELMQFVGAFWANRAFLACFVARCGVDVRGCGGSEGSSMVQLTLAQDSTTSTMASFTSVLVTCLLLSILVGSSAFSASTSKNNAALVQSYTLYDNERQILGCCDEVRPSTKTRDDDEEEDEVEMFYATTKRYFMFPTSGGDDKLLQIRQTSFGCGRLGATVWPSAIALAALLAGDKYRSSIQDKRVLELGSGCGLPTLTAKEVCGSQVLATDYWEGREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D661</accession>
    <name>A0AAD9D661_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sulfotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013729</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D661"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfotransferase" evidence="2">
        <location>
            <begin position="114"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="484" mass="54569" checksum="466CC4FC5CEE1F06" modified="2024-05-29" version="1">MHYSAKRPVVVIALLLVLTAITVYVNVINRGHLDEEKETSTIMLRLPNAENVHGNGHQHHINHRRRRLNNLLPSDPASVYTKSTNANANTQKSSNGNTDNAAAAHASSSYNFAVLIISYHKTGHDLQEDLVKLLIDEFPTPIGPNITAKGVKSLVRRRMHTPVHLCSRLYLQPGTVAVQHAPDLFCNAEKLAKILLEEGDHRKNKDSNSNNIQSSKDLGVKIVHLVRNPFSMAVSNYHYHAKKPIPRPEMWITRQNPCQVTYPNGELFADYVLPSLSKRSYEALNINYDSRLILRSEFEAIANDCESLYQTRKGLETANQFEHLMNLDAPDGLRLATAELTIQGDDNGGDMLRMSNNILKLKQAEKIVQNSWMGGRNKEFQVYTLSLDDFISEPKNSALEFLNFVFDHNEADVSMEQKESAAMKYSQTYLNKKEGSRHITDGKASDKEQLAEYLRHDAVFGPPMKKIEMLVETALAESRNTVML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6W8</accession>
    <name>A0AAD9D6W8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Leucine-rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014079</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6W8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1735013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="328" mass="37518" checksum="253BB07C32C08DC8" modified="2024-05-29" version="1">MADHADDGNDDGIDRDIFVYRGGRAPRNVTHVRIDKSVEVIVDHAFEYNEHLVQVETHDGIRKVGRKAFNRCRSLRNIDLRSVLEIGFMAFDGCNSLRSIDLRSAVEIGGAAFECTSLQRLKLPSIITVEASAFRTCTALSSIEFSERLETIEPFAFLGCDRLQRIAIPLKRDLFSFDHHHQDYNQFDYCEQLTTVDLVGGAHNKTVLSSLHMESWRIEMIAEINRINQVLPNIERLWKTAAIRQWMDSVIDKIDHYKAEHHRYVKEAVTLLELALWKAKLDEKDENAAAGRTKKKAKLDAESVRKEKRITCGADTVIKNVLPFLQLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7A3</accession>
    <name>A0AAD9D7A3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014032</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="618"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="799"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1297"/>
            <end position="1319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1751" mass="195618" checksum="30E0F4454B691BCE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8K7</accession>
    <name>A0AAD9D8K7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helicase-associated domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012275</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8K7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.530">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005114">
        <property type="entry name" value="Helicase_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33418">
        <property type="entry name" value="HELICASE-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33418:SF1">
        <property type="entry name" value="HELICASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03457">
        <property type="entry name" value="HA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase-associated" evidence="2">
        <location>
            <begin position="104"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase-associated" evidence="2">
        <location>
            <begin position="179"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase-associated" evidence="2">
        <location>
            <begin position="259"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase-associated" evidence="2">
        <location>
            <begin position="336"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="396"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="444"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="453" mass="52624" checksum="5AC9550A67CD201E" modified="2024-05-29" version="1">MGAAISSSATAAAESLADDLHLETNTSVTAAATNNNEDASPLPAAATAAATTTSNTPTRRSSRKSQATDFYAPCERVNLETQEQEKENKVISKSKTEAYQKQLWDNNWETHRQELIEYKKVHDTYFVSLETNKQLARWADNQRQFHKKGKMNEERIGLLQEIGFFDEKPQKSPMKESIEEMWEENRQALIAYKGEHDTFFVSQQADKKLARWADNQRQFHRRGEMNEKRHQLLQEIGFFDELGKKSPKKKGAEKKKSLDELWEENRQALIAHKMEHNGSFLFHSKSKLGKWVEYQRRAHKLGKMSVHRFTLLNEIDFFHDEQMGERREEAIRKATDAMWEKTRQELVLYKETHGDYSVAPKSRLGRWIENQRRAYKLYDMPAERAELMQQMGLFPERPEDMVDGRTSPRKKRKKPTYTEEEEDEVGGVSPVRKKRATSASVENNVHEDLAGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D901</accession>
    <name>A0AAD9D901_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">L-type lectin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D901"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01951">
        <property type="entry name" value="lectin_L-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051136">
        <property type="entry name" value="Intracellular_Lectin-GPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056573">
        <property type="entry name" value="Lectin_L-type_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019825">
        <property type="entry name" value="Lectin_legB_Mn/Ca_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223:SF19">
        <property type="entry name" value="LEGUME LECTIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223">
        <property type="entry name" value="VESICULAR MANNOSE-BINDING LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18483">
        <property type="entry name" value="Lectin_L-type_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00307">
        <property type="entry name" value="LECTIN_LEGUME_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042273992" evidence="1">
        <location>
            <begin position="19"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="373" mass="41101" checksum="E62EBDCFDECB6014" modified="2024-05-29" version="1">MISVSATLLLLLLPFVKADFTYVDFNSTSGLSFNGAAEVANCDEGEASTYVKSRLDQVEHTATLELSTSIETANQTSPNDDIALHMGVFGHRHDIGLALDEMKLGCSGRRLTLTPSHPSKAGSVWYDTRVPVLTGFETTFSWTISDHSKECTRHTDRAFSVYEKESCVVHGGDGFAFVIHGDPADASALGVDGEQLGYGGILNSVAVEFDTWTNVDTQQSDDVYQDHISIHSAGPSSPNNSNQHTSLGYWRAYEVADGKVHEAKVQYLPYVETRYFELMSANENLIPYLKDNGEGRRLGTLAVFVDQGIVEDRPLLAIPVNLSLLLDLPQSLAYVGFTASTGRKWEKHDILNWDWCHTDGCHGDLSERIKYEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9P8</accession>
    <name>A0AAD9D9P8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_009845</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9P8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="62"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="308"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="93"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1739302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="360" mass="38898" checksum="ECF904FA6AA4229C" modified="2024-05-29" version="1">MSVSFKDNHDVVLYEIDDPPNSPSAAATNKKQHRVLASGILLSLLIILAIAGGVVAATRTKNDDAPSAATSPAAASSTTSQSLAPLPSPRVRSITSRLTSDPSTQPPLTCRRTETTCLDEDGNVSSCASDGDCPCFNNKQKCRSHRFGNYCDVVCCESGVEERCHDDVTNIVSCIKISEGGCPCSKDGEVQCPSAGVCSTLCCEEDHQTCFDYDDGDPTSCALISSGGCPCHDGKEKCGATIDWAGYCVPLGTCCAAGEASCRDIHGNRSCKKVSEGGCPQKMSYEYWEAMISGTLLTKGSPREVKYFHDIRKRIEELSLKNEDDEDQLVMLRGEEAELFHTVRLRENRKFGKEMKKFVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DA52</accession>
    <name>A0AAD9DA52_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DA52"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1739841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="116" mass="13660" checksum="713E4BA734024E98" modified="2024-05-29" version="1">MTYYLTLFDGKKKSFEDVKHVFNSLYHEDCIITDGDGNTRTREEMKQTHAKKLAMASKCTLLLFRVITFDTIEIKYRIVNDEEDKVVYQLLTTNGDNRVVKRGLWWKIVGERCDCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAL1</accession>
    <name>A0AAD9DAL1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009227</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAL1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="430"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="496" mass="57318" checksum="9EFC4041220D25A9" modified="2024-05-29" version="1">MESMSRILKAKRALPVLFVAAIVTLLVEDGLKTPVLNRSLRRQSSYAVVQTNAPQMHVPATLDLPSQRSLSLNLGGGDCEWTPPTYHVPDDIDFYKTVIAGFPSGDKRMIFLQMEALTGWPAKDEWDFEHIGMSNHPFIKANYPHHEGIWGWEDEADQVVMMVRNIRKSMVEYHDILWDIGYAKTWEDATLFLDRLYSERPPLSDFLVWRDERVLDEVDWYGWFIDYYMEGGLLRDIFTHKKTTKHHWDMLMMPTVYTRAELDYDLIVGADTVVEDAYDPHCATVTEGCAPVAVISAENLRDYTRGKAETALIGNVLKRDSRIGDYVIEQETWDCIWSELIENGRGLKTVYDRPTPEAEYNFSAEMLEAMINELSRLITKYSASPWNTKITANKVVALLTEHRTLIQEELDDLLAGRRVLTEKDFLGPKERERRRNLTSENKEGATPTTDQEGEKDYSRYFFAMDQKLLEVRRIDTRKSLYKKRKEAQDAAKNGTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DB80</accession>
    <name>A0AAD9DB80_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cyclin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_008219</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DB80"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20537">
        <property type="entry name" value="CYCLIN_CCNO-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000093">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02984">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0195">Cyclin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="3">
        <location>
            <begin position="87"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="3">
        <location>
            <begin position="187"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1740967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="292" mass="33376" checksum="39AA9732E75157F5" modified="2024-05-29" version="1">MALTTPIITDVQYIEVCERLKVMRRQESTHYSTPDYLAAEWQARLVEEAAEDDIAREVNELANPNEGSSGQTSSSQINELWREKICEWCYQVVDHFDFNREVVNVAMTYLDRYLATRTVNRRIFQLAAMTALYLAIKLFEPGKLRMSSLIELSRGYFLAEHIVAMEDSMLQALSWHVHPPTPFAFCRDLTKLISADVTPRLRHDISELARFLTELSVCDYYFVTRKPSSIAMASIINAMELMGPHKIDPRYKVQFLHHVVEAGLDIANDDEIINVMSASVKCTSPEGTPPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBD9</accession>
    <name>A0AAD9DBD9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009528</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBD9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041982777" evidence="2">
        <location>
            <begin position="25"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="396"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="538" mass="60171" checksum="632CE8A9DACE5EAE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBP3</accession>
    <name>A0AAD9DBP3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ubiquitin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009664</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBP3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17039">
        <property type="entry name" value="Ubl_ubiquitin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000160">
        <property type="entry name" value="Polyubiquitin-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="80"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="153"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="497" mass="55538" checksum="1A2008D0E96423EC" modified="2024-05-29" version="1">MKISVKISFDNCKEIDVDVEPSDTVAEVIAKIRSEEGIDDNIHLNLFEYSELLNKSEKIAKHVREYVRNVFTLSTVGPLGRLQINVTRGDKTITIDVHGSDTVLKVVKMIAAEGSIPPVEAQDLSFAGLCMDMSHNLSYYGVENNSTVEASALQIFVRTLTGKTITIQGMKQSDTIAVLKRKIQDKEGVPSDQQRLIFSIRGQLKDNRTLADYNIHTECTVHLVLRLRGMISTFTSNDAANNPLVSFLMKSDAERLRTAVPLEALRVKAKAMKANVFSTYAYQESPDLLHESQLQLLCELIDFMWEKTALLTANADRVDMRLTLSEEQLRTIMSESDTSLDDKYKFDRICENFKTLFEQVSHLTRGKGYKVALRATRGPTNSCIDFHCDGIYASSTSQMPINSPTEYKGGQICFFVNDQLHFVPRPIGSLVQHPRNVLHGVTQVTEGMRKSLFIVDRDNGLGEGGVIVLSSDDVASFLAHRALAAGRKRKRVVDLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DC09</accession>
    <name>A0AAD9DC09_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Wax synthase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_007544</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the wax synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DC09"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044851">
        <property type="entry name" value="Wax_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032805">
        <property type="entry name" value="Wax_synthase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595">
        <property type="entry name" value="LONG-CHAIN-ALCOHOL O-FATTY-ACYLTRANSFERASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595:SF57">
        <property type="entry name" value="OS04G0481900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13813">
        <property type="entry name" value="MBOAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="178"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="316"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="386"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="423"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="455"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="Wax synthase" evidence="9">
        <location>
            <begin position="349"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1741971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="499" mass="55083" checksum="D77CBAAAE08A0283" modified="2024-05-29" version="1">MLIQNNTIHLINTFKLCRQRNNSTTYHIPNILTQQHFLSQELIMAAETPTNNFIAIPDLQSVNASIGEILSSPLSLFQSSCGASTSTVGQLQDKISSLDLSLTIPEHPELRALGYSIGTNSFSGKYNLVLPDLQAAAEMAVGGSISIAVGVLFAAMLYHFVLPSREESSTSPTKTRTLLIGSLICVISIMPYVLFDVVGIQNTAARFSVMAPFILYLFRTFEAAAGFVPRGADESFRRYCTYFATPAELLFEQRVTRKEMIQSSMDVMKCAAIMSIVCTILSPSGYTPFGAISAGEFYEPVTVENYLNPRHLGNCFAIAFFFQSGLALGTAAIGNLVQILTGYKVLRAMKNPMLEATSPSDFWGKRWNLLVHVVLKRGVYKPVRRYASALIASLAVFVASGLFHEWVVHAVFLYNKQSEGVVLGSNTAFFVWNFVVIACERMLVATKGVQSLKKVLPRFMVTVMIIMSSLPAAHWFGGPYLNGNFFSDYETFVPMIRKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCE7</accession>
    <name>A0AAD9DCE7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">PRiA4_ORF3 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_008899</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCE7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.30">
        <property type="entry name" value="MM3350-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024047">
        <property type="entry name" value="MM3350-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012912">
        <property type="entry name" value="Plasmid_pRiA4b_Orf3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41878">
        <property type="entry name" value="LEXA REPRESSOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41878:SF1">
        <property type="entry name" value="TNPR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07929">
        <property type="entry name" value="PRiA4_ORF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159941">
        <property type="entry name" value="MM3350-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="446"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1740804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="496" mass="55792" checksum="14593720D1426C2D" modified="2024-05-29" version="1">MSGGIDYSKWDNLSVSDDSSAADDYNDESYNDDDQQYHEGDDIISSLQHQSTVADNDTSPTLSGDYSPAEIALLKKGIAYEKEQDSNDDNDIDWLLVGPLKNIRVHPNDKSTSMYSSIIYTEDPNTYIPDRSEYIDDRVQKWGIEPPSSQEGGSGDGLLDLMSRMMMSSSTSSMEYYKHNLENPELQFIDSLIERRSKYNNSDEITAAMKFTYVVRIELCECEKDVWRRVRVPSGIGLSIFHDQVICPVMGWARGYHGYAYEDPRDGTVIGPAKNSAYIDTMHVPMHYKKVMDDKGCPLAALLIKKGDIAYYNYDLGDGWMHRLVLEDIVAEEDSVTLMAGEGACPPEDSNGLDSKGCGAYADFLKAYKRNPKKMKMKEAVKEASRSINYSKPWAGGPPISFKPLEFNIGYHRMLLTLMLAGPALKTKKGNFAMPDGKYKESMKGCDNCGNRLKPLSKCTGCRKVSYCSRECQLQAWKLHRSECKKHSDKKGKTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCF1</accession>
    <name>A0AAD9DCF1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008914</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCF1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="99" mass="11039" checksum="2D61C9E6EF2500CD" modified="2024-05-29" version="1">MHLIPLSAANEEICKLLKATKVPYILIYKRSEGEVARFACPPSKMQLLIDALHEHASPLNDDLLPMSLSEEPTIEPLMEDDSIESTLMKGSEMMDALMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCG4</accession>
    <name>A0AAD9DCG4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TLDc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006897</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCG4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006571">
        <property type="entry name" value="TLDc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07534">
        <property type="entry name" value="TLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042060943" description="TLDc domain-containing protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="TLDc" evidence="3">
        <location>
            <begin position="141"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1742332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="328" mass="35790" checksum="4A6175A7A75CC384" modified="2024-05-29" version="1">MKYTTKTLAAASAALLSCESAVAFSSTNLSSPRSRSIIGNGINNSGNIQQPQQPTSTTLYLGDFFNFGKKEEQETTPPTPEEEAAQTGYVDDEDPIEKIFGVFFGKKEAEPMGMKRFGQERFPEQYPAVLDEWADPVEGDDKEMELLRPLLKNTNLETRNLRLTYDANRDGYDPVTFHSKVDKQGGAIVFCTTRAGIQCGGYNPKGWVGYGEARGSIAAFLYILGGKYAAAGAPAIKLRKVGGPGLAQMDLPESGPSFSPDALVIPLGKDGRLARSKLGSYYERLPDGTNSLFGKDSNVQLRDLKVYHGVYAEGEYIPFTDAEPFALY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCN9</accession>
    <name>A0AAD9DCN9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycosyl transferase CAP10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_008130</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCN9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF35">
        <property type="entry name" value="PROTEIN O-GLUCOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
        <property type="entry name" value="Glyco_transf_90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00672">
        <property type="entry name" value="CAP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042270222" description="Glycosyl transferase CAP10 domain-containing protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="4">
        <location>
            <begin position="181"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1740878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="453" mass="52738" checksum="3581AF89219EBA4F" modified="2024-05-29" version="1">MPSFGIKSFVCVILLAMGSGGILQNSYNFHEHLNNIQTVQHDLSAPQATAQGTTEAEEKMEIEEQTLAGDKQQITHVCAKETSSSIKVANYQFPSVQERLQYYMGDWYNRSDWTVPDSDCKLLRKVNDYQKVLRDVMFHTTDFKESMSSHRKRTKAVYCRDTYDIINNALDEADSSNNHWIVSFGDRTHGIKGTLPIITKARRSALSFAPQPIVWLLNKERHYNDLESYHRDIVKKGKEVPRSEKLSKVFWRGSTTYNEKAGTSRLDYLAQWINYHDNHTDIAFSNSKVVQTNTNFKREYVKRQYVRKKQSLLEMNRYKYLLSIEGNDVATGLKWMLYSNYVVFMSRPTVATWAMEDLLVPFVHYIPLANDYSNLLEMVKWANEHDEACHEISQRATEFMEHLWLSKQAKRDTRYLQKALVKSYVNQFDDALSRCAPNTEKMANRSIIHLQKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDE1</accession>
    <name>A0AAD9DDE1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC1 kinase family protein</fullName>
            <ecNumber evidence="3">2.7.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008031</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.-.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDE1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05121">
        <property type="entry name" value="ABC1_ADCK3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050154">
        <property type="entry name" value="UbiB_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566">
        <property type="entry name" value="CHAPERONE-ACTIVITY OF BC1 COMPLEX CABC1 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566:SF119">
        <property type="entry name" value="OS04G0640500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="2">
        <location>
            <begin position="4"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="406" mass="44844" checksum="8F42858ECA8409E4" modified="2024-05-29" version="1">MLKDVEALVSTITDTPVAAASIGQVYKVNIPGKGDVAVKVQRPGVRTLVERDSELLLTVARFVESLPALPSSSSTGDATNKQTRLINTELVSTTKEFMSRIFEELDYRKEASNIAQFSSLYSSSRRDGTSKDVSVIVPKVYTELCTENVLVMEWIYGEKLTDVTGTASNTGEQSSTVEENLALVKVAIDSTLSQLLVEGILHADPHAGNLLKVTLEDDSVTLGYLDFGIISTIPEQVRDALICSVALQVFSRDVDAVSSLFGELRLIPQHILDDDEERAALAEALEITFENSLLYPEAAAGDDDTTAIPDLKFDKLLDSLSRLVPRFQFDLPPYFINNARALSTLVSRGHCQVTRPYIQCTDYHIPICIEQATEKSIEERSSCKDITKFDPIRRWQDRSDKDTTIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEX5</accession>
    <name>A0AAD9DEX5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEX5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="406"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="430"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="443" mass="50091" checksum="C58D4DEC6B20DD57" modified="2024-05-29" version="1">MQSVNPRRGSEDSLDLLAATANINAMREKVAEEISKTSPTQHIDADTVTVRTIPTCFNPARKTIKKKSKDENAESDASDTSEDEAAENERKKVKRNPSTSSFDVLLTALEGDLEKLDKKNEEKEKVPSVIQRANEDELLRRLSKDSLFSVISEDDLVCQPATHTQDNLSRKRKQSHLATLLNARSSFTMPSEPMESDAILYPAHGMNLDYARRLQTSHSTMASLESAMLRNDFARRQLAFRDLQRREFASRMMQNNLQNRLHNNLQNNKGPPVPVVDPKPEQQLKLPGKLPSEGKNVTLSDRDKPMEAKENKNEPPTTSIDGTGFPLRRKEKVEEPIKIPPEEALKIFLSAHGEKGETLREAMLKAITDAEGSLATIHSWDRSQGLRKCHSRTVVKTRRSRAQLKAFLTGVEPPKEPHHNRKRQKKSSSKKMDDVFGPPRDRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGJ0</accession>
    <name>A0AAD9DGJ0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sec20 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_004535</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGJ0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15861">
        <property type="entry name" value="SNARE_SNAP25N_23N_29N_SEC9N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044766">
        <property type="entry name" value="NPSN/SNAP25-like_N_SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056173">
        <property type="entry name" value="Sec20_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230:SF79">
        <property type="entry name" value="T-SNARE COILED-COIL HOMOLOGY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230">
        <property type="entry name" value="VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03908">
        <property type="entry name" value="Sec20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Sec20 C-terminal" evidence="8">
        <location>
            <begin position="138"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="37"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="161"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1745244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="215" mass="24082" checksum="0EF2C478124C8A11" modified="2024-05-29" version="1">MADVQYWDDTLNDEVQSIQQLISSAESGDSMKKASTLDRAEKKLRAATGTKKSYKMETRLVADPNQKRMYENKLERLSEDLARCANDIKAMKGGMQRGELFVGARGQSSNMDGSEMNGVEAGDVMINEMNNIQDKTKDSLANTKQMVKASKEVGEATMGELLQQREQIRNIDNEAMRMEDNLQRADKLIKAFGKRMATDKLIQCFACINILLLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGN9</accession>
    <name>A0AAD9DGN9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002430</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGN9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="25"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="151"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="233" mass="27020" checksum="8F6572C81A791BFC" modified="2024-05-29" version="1">MNNLAQRLLIPVTLRSAAASASLIQRSFTTPRPRASSPWTPKKKDDDTTDTPKSLLKVDSSYEKDVLLWRKDLLEAELRLVKEYLERFPVRKAEADEQVNSNISNKDESHDDVVDKDKDDFMSRVASPTREHLRLKKRKAMSKESVLLMEVDKLKEDLGKAELKIKVLEEENEQLRQQQHNNTVMQQDHLTCPTLALRQALNLMLVMTFILTRRRNTKKMMNKNSLLTCLTVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHB6</accession>
    <name>A0AAD9DHB6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHB6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="137"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="349" mass="37576" checksum="9AAAD3AFF7D4BD69" modified="2024-05-29" version="1">MMGVAVGTSGSSSSSVVDSINSSSNASGNSKEARMESMAAMEIAKWNEFDLIQDFAQQCYHSANEAIQRLSTDRLSDSANLTVHDGMSGDVGGSGNNRDGNHQAAVPGGDAALNHHHDQSQTTMPTSTPTAGSVGPSSSSSSASAAAAAQSSSSMLPRTLADAGIGRCYKPLTVKIAGRVHVSTVQITHGQMMRLITQNIVQASFLNSCGDQWVGSIHDEHDHVSILTTDGTHIIPTPTYASGTPHPFPSLEAVHCLQYLVSELLHTSIPSSINKFRAATEANAVVSKRLYLVKCEYRAPMRALWESYTALNAAPSWNLWRAICVFIMDMSKMLHHHHHHHRKLVEKMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIJ6</accession>
    <name>A0AAD9DIJ6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sel1-like repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIJ6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052945">
        <property type="entry name" value="Mitotic_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATORY FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="20"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="338" mass="37065" checksum="C704D1814C733C43" modified="2024-05-29" version="1">MPTPSLPTLYFDQEGSSEKQDALKPLPSEIVNNVSSFLDWGDLARLACVQSSWKNVVADAAEFGGREATWELTTCLLGGEKLQEEETTDSVLYLAHSVDTRGLQTNEPLAVKYLTQMAGVPVDESQLPKIAASREIEHECNSILPNDWKSSVDSTNVDGADEEALLLLARCQLDGTGLDSPNPELALYYLQAAYHMTKSVKAAHTLALIYEYPQQSNNLVPIDVYAAFEWFKAAAEGGCVPSMAELALCYELGCGVTQSDENALDWYMKAAAAGCSSAHFSVGEHYEEGRSVRLDHEEACIWYHRAAVMGEEDGVRGLRRLEEVARRVLPNVGDILNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIZ8</accession>
    <name>A0AAD9DIZ8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Integrase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002627</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="706"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="729"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="771"/>
            <end position="780"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1613" mass="181927" checksum="F83E229897FBCA07" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJF8</accession>
    <name>A0AAD9DJF8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PSI-F</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001908</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJF8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041984878" description="PSI-F" evidence="2">
        <location>
            <begin position="18"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="158" mass="17637" checksum="E5FE3D5DAB79588F" modified="2024-05-29" version="1">MMKTSSFIFSLVAVACAFRVNVCAFSPSPLITSRTGPARHRSSLASATVGSSDSLGSRPANPLRNRSMKEKAELETIRSELVQKYIKLGHSEDYATNEVNYFLEDSERSAQYVEMRRIAMARGNDLGIETWVQFGGAFLFGWLISWVANYLPNLQAQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJY3</accession>
    <name>A0AAD9DJY3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Autophagy-related protein 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_000888</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJY3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990316">
        <property type="term" value="C:Atg1/ULK1 kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034517">
        <property type="term" value="P:ribophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040040">
        <property type="entry name" value="ATG11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019460">
        <property type="entry name" value="Atg11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045326">
        <property type="entry name" value="ATG17-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13222">
        <property type="entry name" value="RB1-INDUCIBLE COILED-COIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13222:SF1">
        <property type="entry name" value="RB1-INDUCIBLE COILED-COIL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10377">
        <property type="entry name" value="ATG11"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF04108">
        <property type="entry name" value="ATG17_like"/>
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    </dbReference>
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        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0072">Autophagy</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="Autophagy protein ATG17-like" evidence="7">
        <location>
            <begin position="472"/>
            <end position="820"/>
        </location>
    </feature>
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        <location>
            <begin position="1006"/>
            <end position="1115"/>
        </location>
    </feature>
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        <location>
            <begin position="407"/>
            <end position="440"/>
        </location>
    </feature>
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        <location>
            <begin position="957"/>
            <end position="983"/>
        </location>
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        <location>
            <begin position="1005"/>
            <end position="1030"/>
        </location>
    </feature>
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            <begin position="418"/>
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        </location>
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            <begin position="966"/>
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        </location>
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        <location>
            <begin position="1013"/>
            <end position="1024"/>
        </location>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1748949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1120" mass="121812" checksum="3AA9219196AFD0DC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2LLZ6</accession>
    <name>A0A7S2LLZ6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_010387</name>
        <name evidence="3" type="ORF">SMAR0320_LOCUS13559</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Transcribed_RNA"/>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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        <property type="entry name" value="Znf_RING"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
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        <location>
            <begin position="5"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CAD9610398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1739071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="194" mass="21799" checksum="C3522B16EFA8E8F2" modified="2021-06-02" version="1">MNEECPICLEELFDEKGVACNGAVARIMCVHLVHSDCLQRAGRSLNPDGRRYGVGGFGPRAGCPLCNQPVSCWEVLQDVASFPAFWVKRILGVLEHIGPSGGPVDVVAVRSRLEVDETLTKRQKEIMAQGPFREALLEGKRKLVWEEIDGGFRNGGSERMESKDYLWYWNEQDNTLWLYKWGEAPNRAPADADF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1GXR5</accession>
    <name>A0A8K1GXR5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical chloroplast RF66</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ycf66</name>
        <name evidence="2" type="ORF">QTG54_017248</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
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    <reference evidence="3" key="1">
        <citation type="journal article" date="2021" name="Front. Plant Sci." volume="0" first="0" last="0">
            <title>Chloroplast Genomes for Five Skeletonema Species: Comparative and Phylogenetic Analysis.</title>
            <authorList>
                <person name="Liu S."/>
                <person name="Xu Q."/>
                <person name="Liu K."/>
                <person name="Zhao Y."/>
                <person name="Chen N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CNS00100</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="UAM91449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_058701.1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Ycf66_N"/>
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    </dbReference>
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    <keyword evidence="1" id="KW-0472">Membrane</keyword>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="UAM91449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="103" mass="11598" checksum="E4BA43C780E76993" modified="2022-08-03" version="1">MLNFVFSPNVLLGFILGSSVIILYFLRLVKPEVARDEDIFFATIGLLYSGILVIHGWRLDPILLFSQVLVITAVLAAGWENIRLRGVLAMLALRDIEENKKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1GY77</accession>
    <name>A0A8K1GY77_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12 13">ATP synthase subunit a, chloroplastic</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">ATP synthase F0 sector subunit a</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">F-ATPase subunit IV</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12 15" type="primary">atpI</name>
        <name evidence="14" type="ORF">QTG54_017242</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="15"/>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2021" name="Front. Plant Sci." volume="0" first="0" last="0">
            <title>Chloroplast Genomes for Five Skeletonema Species: Comparative and Phylogenetic Analysis.</title>
            <authorList>
                <person name="Liu S."/>
                <person name="Xu Q."/>
                <person name="Liu K."/>
                <person name="Zhao Y."/>
                <person name="Chen N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CNS00100</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a, b, b' and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12 13">Plastid</location>
            <location evidence="12 13">Chloroplast thylakoid membrane</location>
            <topology evidence="12 13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the ATPase A chain family.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MW679506">
        <property type="protein sequence ID" value="UAM91441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_010200955.1">
        <property type="nucleotide sequence ID" value="NC_058701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1GY77"/>
    <dbReference type="GeneID" id="68638097"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00310">
        <property type="entry name" value="ATP-synt_Fo_a_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.220:FF:000001">
        <property type="entry name" value="ATP synthase subunit a, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.220">
        <property type="entry name" value="ATP synthase, F0 complex, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01393">
        <property type="entry name" value="ATP_synth_a_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045082">
        <property type="entry name" value="ATP_syn_F0_a_bact/chloroplast"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000568">
        <property type="entry name" value="ATP_synth_F0_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023011">
        <property type="entry name" value="ATP_synth_F0_asu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035908">
        <property type="entry name" value="F0_ATP_A_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01131">
        <property type="entry name" value="ATP_synt_6_or_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42823">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT A, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42823:SF3">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT A, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00119">
        <property type="entry name" value="ATP-synt_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00123">
        <property type="entry name" value="ATPASEA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81336">
        <property type="entry name" value="F1F0 ATP synthase subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00449">
        <property type="entry name" value="ATPASE_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="4 12" id="KW-0138">CF(0)</keyword>
    <keyword evidence="13 15" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="6 12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="13 15" id="KW-0934">Plastid</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="23"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00074744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1732199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="UAM91441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="242" mass="27140" checksum="74A5939C5BC53F0A" modified="2022-08-03" version="1">MYPDNFSSSTFTFLAEAEVGKHFYWNIAGFLVHGQVLVVIWFVIFLLLIFSFLGTREADRIPHSWQNFMESALDFIVDIARNQLGESFYREWIPFIGTLFLFIFGCNWAGAVIPWKLIELPEGEFAAPTNDINTTVALALLTSFSYFYAGLSKKGLGYFKRYVNPIPLLLPINILEDFTKPLSLSFRLFGNVLADELTVTVLTSLVPLVIPLPIMLLGIFAGSVQALIFSTLAAAYIAEALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XR24</accession>
    <name>A0AAD8XR24_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_017071</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000078">
        <property type="protein sequence ID" value="KAK1732246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XR24"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042171">
        <property type="term" value="F:lysophosphatidic acid acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006654">
        <property type="term" value="P:phosphatidic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42886:SF29">
        <property type="entry name" value="PUMMELIG, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42886">
        <property type="entry name" value="RE40534P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="74"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="405" mass="44468" checksum="77199E9B86F5BD8E" modified="2024-05-29" version="1">MTSTSRLLRQWWSASDSKLLAQSESRLLDSLVVKHAHVRKKFNIGGLNILEFNKAPAAPAPAGINNNQPAHPTIILTHGFGSGLGFFYRNINDLLQSEKVSRVICIDWLGMGGSDRPPCWESPVRSLFHSSSTSNGFSLCNSRFTPSRAIDFFLDPMEQVLQHDNSNEDGLYFHPDEKICLVGHSLGGYLAARFAMRHNNKSNGSGANISKLILASPVGFQPPPPPGQRLPFSNLPPAMRLLDALWSANFTPQQIIRLMGDKRGKRMVERALRGRIPHLSSSDVELLAEYFYHITVAPPSGEYAMNSLLEPAVASEGGAGVYARESLGGGIMTEMLSQNGESCIKSVKVLFGDRDWMSFNQSAAVKEMEEIQSKMGIDANVHVLSGAGHHLYLDNADAFVRHVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XR53</accession>
    <name>A0AAD8XR53_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WRKY19-like zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_017015</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000075">
        <property type="protein sequence ID" value="KAK1732294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XR53"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056866">
        <property type="entry name" value="Znf_WRKY19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24906">
        <property type="entry name" value="Zf_WRKY19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="377" mass="40536" checksum="E9AFCFAC0C3CDED3" modified="2024-05-29" version="1">MDDRWGIIGGTTTSQLTLQLPSSIIIIHPRRGSPCKIRSVSPSSGPGESTIVRLAFYGFGHAYPASPRPLQHQPCTALSCLLPPSLSPCYRCDGQWRWRSEGLSINGGVCVRHGAKRKLCSSEGCTNKVIEGGVCRKHGAKVKRCSSEGINNGVCVKHGAKIKRCSTGGCTNKAQKGRVCYRHRAKAKRCSSDGGTNIVTNEGVCLRHGAKIKRCSPEGCTNNAQKGGVCRGGVCVGHGTRAKRCSSEGCTNVSVKGGVCKRHGAISIVNVKLYNSEGANQVQRGGVCWRHGANRITHNESTAFGSEFEKTTATRTSPNQRAPRAAAREGQEGSRVPQEVAILCQDIIEWLCGEHAPSISCILKQHHLLLVKYELEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRJ0</accession>
    <name>A0AAD8XRJ0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_017028</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000076">
        <property type="protein sequence ID" value="KAK1732293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRJ0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="181" mass="21313" checksum="B5329BAA2F836F4E" modified="2024-05-29" version="1">MNTTKLQVEERKKIDSKDDDDFPFVLCTPTKNDNDEIDAQDTIFEEDKSPRLMNFFLKPRPRRSRQCPTGWHQEQIGMRTDSALKDMAKDSTNEHIMERNPSQQQQFTPISSVPITPPVVINLLKRRRRPSQDEHQEEKDEGDDNSPSKKWPLFPSLGRQPMQQQQQDHPVLRRPVARRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRV2</accession>
    <name>A0AAD8XRV2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000061">
        <property type="protein sequence ID" value="KAK1732684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRV2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="339" mass="36321" checksum="E2598C0A61762B38" modified="2024-05-29" version="1">MSTKQRKLSEAAASKSGEEEDIGALIYRESQLRKKEAAAAAEVKSGRNSSCRSTSSTRPARRAAAAAIHGDDPSAVAPGRKVVTKRKRHSTPDDDEGNKAARKVAKRRQRKRPYCSADGCTNQVHQGGVCRRHGAKLTGRNCSHEGCSNHVVNGGMCVRHGATCTKKKCSKEGCKNYAQNGGVCIKHGAKVKLCSNEGCTTKVVKGGVCIRHGAKLKRCSSEGCTNQVIKEGVCRRHGAKVKLCSKEGCFNQARKGGVCMRHGAKPKVKQCSSGGCKNHVVKGGVCIRHGAKPKVKQCSSGGCKNRVIKGGVCKRHGAYRNPWTSQMHSVNHADPHMMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRZ2</accession>
    <name>A0AAD8XRZ2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WRKY transcription factor 19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000073">
        <property type="protein sequence ID" value="KAK1732325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRZ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="263" mass="28288" checksum="FBF22DA76150BB68" modified="2024-05-29" version="1">MERSANTKPAATEDEEDYAALIYQESQRRKAEAAALAAAAGKNKKKQYYISKNGATRTSTCISATVAGDGSSTTRVAGGKAVHTRKRKSSEWNDDEQAPKTKKFAKKQYQYSKLCSADGCTNLAREGKVCCRHGAKVTLCRHDGCTNQVIKGGVCCRHGGKKICSRDGCTNQVQRGGECCRHGGKKLCSREGCTNQAQRGGVCCSHGAKIKLCSRDGCTNHARKGGVCCRHGGKTLCRYEGCTKHDQGGGVCRRHGATHKLYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XT52</accession>
    <name>A0AAD8XT52_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">rRNA methylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_016180</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000054">
        <property type="protein sequence ID" value="KAK1733042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XT52"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000479">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010719">
        <property type="entry name" value="MnmM_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35276">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35276:SF1">
        <property type="entry name" value="TRNA (MNM(5)S(2)U34)-METHYLTRANSFERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06962">
        <property type="entry name" value="rRNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="6">
        <location>
            <begin position="465"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="47"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="141"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="443"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="141"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="449"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1733042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="692" mass="76923" checksum="B6B1727A2ACBDEFA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTL0</accession>
    <name>A0AAD8XTL0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015947</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000050">
        <property type="protein sequence ID" value="KAK1733388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTL0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="73" mass="8444" checksum="BE23BDBD525FD478" modified="2024-05-29" version="1">MVGQLFRLGRDDTAVVPEICEQVKEEEQEAPQQQQQRRRPNRSKMLRIQASTRLISSTVAFPREDDNLSVGFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTL1</accession>
    <name>A0AAD8XTL1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015887</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000049">
        <property type="protein sequence ID" value="KAK1733472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTL1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="178" mass="19900" checksum="033E692728DB6B4A" modified="2024-05-29" version="1">MVLCVVVRHKPHPATLKIRSDEKIIHYHTTKAFYYSTMTSSITLLILLLSTSTSFTTLIHAFSTVKTYNNFRHPFKPSSSSSSLAQQPQPNFGDWTNDDYLNNLGGDGDGSANDESGGAENNYTPPRNELTDEEITAWALNAASFYNTESSVEEVYGVKREGPPRREEGSEVDGWDYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XU66</accession>
    <name>A0AAD8XU66_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_015229</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1733971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XU66"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052201">
        <property type="entry name" value="LRR-containing_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24111:SF0">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24111">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="514"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="463"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1733971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="536" mass="60725" checksum="89D171EB1FE69A61" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XU76</accession>
    <name>A0AAD8XU76_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000047">
        <property type="protein sequence ID" value="KAK1733582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XU76"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="200" mass="22357" checksum="21CBBB21D559382D" modified="2024-05-29" version="1">MVEYEPQAIHHKTSESMGDDNSKEPSACLREEHDKEEDRQRMEEHSSSSLTLDGFLSVSPTPLSSSLYSSMQQDDFDEAEPELIARAKRCEEIMKLSQQAIDAEAARVNAANIKPLVWAKPAFEIDSPAADTATDDVAAVLTRHKQKSQVKPQGKRMSTREEVQAFVEFTDKWMPSAKRRSTSGNDDEGVGIGRNVWRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XU90</accession>
    <name>A0AAD8XU90_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Histidine triad nucleotide-binding protein</fullName>
            <ecNumber evidence="5">3.9.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_015871</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.9.1.-" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000049">
        <property type="protein sequence ID" value="KAK1733456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XU90"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01276">
        <property type="entry name" value="PKCI_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.428.10:FF:000005">
        <property type="entry name" value="Histidine triad nucleotide-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019808">
        <property type="entry name" value="Histidine_triad_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23089">
        <property type="entry name" value="HISTIDINE TRIAD HIT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00332">
        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00892">
        <property type="entry name" value="HIT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="4">
        <location>
            <begin position="28"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="2 3">
        <location>
            <begin position="121"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-AMP-histidine intermediate" evidence="1">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR601310-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601310-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1733456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="137" mass="14747" checksum="FED1243AD2D482BC" modified="2024-05-29" version="1">MSDEVAAAKAAAAEYKSSDADGAGPETAFDNILSGKWPSTKVYEDSTVLAFRDINPQAPTHIIVIPKHRDGLTKLSNAREDQEGILGHLLFVAQSVGRKECPEGFRVVVNDGEQGAQSVYHLHLHVLGGRQMGWPPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV99</accession>
    <name>A0AAD8XV99_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rhodanese-related sulfurtransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015155</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV99"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022111">
        <property type="entry name" value="Rhodanese_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020936">
        <property type="entry name" value="TrhO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040503">
        <property type="entry name" value="TRHO_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43268:SF7">
        <property type="entry name" value="RHODANESE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43268">
        <property type="entry name" value="THIOSULFATE SULFURTRANSFERASE/RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12368">
        <property type="entry name" value="Rhodanese_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17773">
        <property type="entry name" value="UPF0176_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="335"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="579"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="48"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="602"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="672" mass="73713" checksum="26BF548310882383" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVY9</accession>
    <name>A0AAD8XVY9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014472</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVY9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="90" mass="9920" checksum="929A640681C979B0" modified="2024-05-29" version="1">MPLRSVRRTYNRVAGSTEENANSPLSPSTSFDGEDEENKTVNDPLNQSGLASEPQLPPIQNEINVNLLDGATKKFTIKCDPAWTVAEFKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWV0</accession>
    <name>A0AAD8XWV0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWV0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="503"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="526" mass="59216" checksum="483FFA1B2D3B21C6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXA5</accession>
    <name>A0AAD8XXA5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXA5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="162" mass="17982" checksum="4D99AF52C781B77A" modified="2024-05-29" version="1">MNSFLLLSYSFRRRTSSSYAMIASSIKNTHQSSHFINYCRRPLSSTAATPPKQQQQDDPTYTLLFHRSPSRSTPPRAMLGISTFNLSYWTWYVADFTPSVNAAAQSKLALGQIDAETLDILLIDPKMGYVGLGVSLAIWGGAFMYVKQLVSACGRGVMAVWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXH2</accession>
    <name>A0AAD8XXH2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014038</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXH2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="351" mass="38076" checksum="1829304D6920233F" modified="2024-05-29" version="1">MSQTEVLRLISKRKHQSNSTVIATPASTGVRDYSNVKNNPIVTAKKFTSAQNNNHDAGGSVIYSTVTCPDGSILKFSPDKQHGTTSIVLGPGEHGIPTTARHVPHNTCIIRLVKNAADKTYSIELVVVGSSCMVTRAGNSFVVKSVTDILSDAVANGNDTSSSNMIIRDGDIIEPYHRECSVEEATSKGTYHPFKVNVSSGGTTAALNPNAKWLYSRCSIAKSNMEYPNSTLHLAAKILTEIRQHYSSKDGSEATEGEHSRTIQNLVFKLIDEGKKRDLQFVFDVTSKSHDLYKDEGLTVGALWDVAAFCGGDENVDNDGLKVDMNTSTPTPHNDVAGQSVHDNNVIQQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXT4</accession>
    <name>A0AAD8XXT4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">NADH-cytochrome b5 reductase</fullName>
            <ecNumber evidence="12">1.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_014007</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2 Fe(III)-[cytochrome b5] + NADH = 2 Fe(II)-[cytochrome b5] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46680"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11 12">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.2.2" evidence="12"/>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXT4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090524">
        <property type="term" value="F:cytochrome-b5 reductase activity, acting on NADH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000021">
        <property type="entry name" value="NADH-cytochrome b5 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000019">
        <property type="entry name" value="NADH-cytochrome b5 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF185">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11 12" id="KW-0274">FAD</keyword>
    <keyword evidence="3 11 12" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="9 12" id="KW-0520">NAD</keyword>
    <keyword evidence="8 12 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="14">
        <location>
            <begin position="36"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601834-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1735393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="307" mass="33885" checksum="43122967AD380F04" modified="2024-05-29" version="1">MIELPFPAPILIAVVIILATTALLFGKKSKPALDAVEFTPLPLIKKESLSHDTRRFTFALPNGPTGKLGLPVGQHITLKFTETLPDGKTKNHQRSYTPTTGDDTLGTVTFVIKVYKAGVHPKFPDGGKMSQHLDSLQIGDTVDMRGPKGHMTYHKNGSFTVHPMLKRDPDEKRTAKHFGMIAGGTGITPMLQIIHAALRDEPNSDVTCSLLYANQSEDDILVREELEAAVEKFGGRFKLHYTVDRPPQDWKYSTGFITKEMIEKHLPAVSGDGSTQILMCGPPPMIKFACLPNLEALGFKKSDYFIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XY27</accession>
    <name>A0AAD8XY27_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_013706</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XY27"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019607">
        <property type="entry name" value="Putative_zinc-finger_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF46">
        <property type="entry name" value="LEUCINE RICH REPEAT-CONTAINING DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10650">
        <property type="entry name" value="zf-C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="5">
        <location>
            <begin position="30"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="3">
        <location>
            <begin position="30"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="80"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="89"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1735543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="835" mass="94268" checksum="18FD76291C983B49" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZ65</accession>
    <name>A0AAD8XZ65_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013286</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZ65"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="490"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="774" mass="85969" checksum="3FA30DA27C9A4A50" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZ90</accession>
    <name>A0AAD8XZ90_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012678</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZ90"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041906111" evidence="1">
        <location>
            <begin position="20"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="197" mass="20626" checksum="3DD0EEA63FC8A190" modified="2024-05-29" version="1">MKATAIVWLLQLFISFSLSWGFGAVKRSLIIPGTASSSRAEFLSSIVAASSLLVPVGITNAFDGGVGGLGKTRPQTGVVFRDEEAAAATTQSKLGVTYELLAPDGSPAVVSFNAPWPLLQTAAGIESRDIGGGFESAFVQVTELQKGSEIKPAQLKEAIFSSKGKFGMYGSPTDIKLRLVSPENSKSPAIYLSPSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZQ7</accession>
    <name>A0AAD8XZQ7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012987</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZQ7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="434" mass="47541" checksum="714E36DC1D1D76DB" modified="2024-05-29" version="1">MQPLKDDSHDNRKPRPRGLTSDENSSLDGAMHRGHHTTSGSNNGGGKSKLSKSPFNRVKSMGGGLTIKEGEPTVISNEQEAQMREKRKAFTDFHNMGVDSTSAFLGDESSNHRNSFFLTSVAYPAANARVLPTNNTRGGAQSYDKKTTISPSTSENALKAIGAPKDELDNSADIAPERALRPVRGPESWKKGERHSIIPAILCVCPFQVLSNVMSDDSGNPPSRPPSGQSLLSSSPINGYGIGSMIADDEHNESNQNGWFFADHHQPQPRLSSNKAGVPPSAFGKIMLGKATVAALGVRSFFNEVYGWTSGIFVLRQNYLFEYRDDDNLKGLPWGYAHLQLAEAYPHKHFVNALHLDFFEKPCIKSGKRSLLLRVEDKGERDRWVSLLQAAARTTIHDLYDVDVSGGPEFGRGRYAVVRPARRSKLGGSHLMTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0B4</accession>
    <name>A0AAD8Y0B4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">40S ribosomal protein S13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_012709</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0B4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.10:FF:000003">
        <property type="entry name" value="40S ribosomal protein S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.860.130:FF:000001">
        <property type="entry name" value="40S ribosomal protein S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_A">
        <property type="entry name" value="Ribosomal_uS15_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_uS15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023029">
        <property type="entry name" value="Ribosomal_uS15_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012606">
        <property type="entry name" value="Ribosomal_uS15_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="uS15_NS1_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006331">
        <property type="entry name" value="PRK08561.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11885">
        <property type="entry name" value="RIBOSOMAL PROTEIN S15P/S13E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11885:SF6">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08069">
        <property type="entry name" value="Ribosomal_S13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01386">
        <property type="entry name" value="Ribosomal_S13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="S15/NS1 RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00362">
        <property type="entry name" value="RIBOSOMAL_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS15 N-terminal" evidence="6">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1736687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="151" mass="17155" checksum="B361CA3FF6E23D23" modified="2024-05-29" version="1">MGRMHAPGKGISKSAKPYKRTPPSWCKVSSTDVEEHICKLAKKGLTPSQIGVILRDSHGIAQVHSVTGQKIVRILKANGLAPEIPEDLYMLIKKAVQVRKHLERNRQDKDSKFRLILIESRIHRLARYYRTTRKLPANWRYESATASTMVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0R8</accession>
    <name>A0AAD8Y0R8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011785</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0R8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="41"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="118"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="216"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="400"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="493"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="436"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="409"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="493"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="571" mass="63976" checksum="6791380FD95997FC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0S3</accession>
    <name>A0AAD8Y0S3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011782</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0S3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="107" mass="11775" checksum="33CB46C3ACF6C6E1" modified="2024-05-29" version="1">MASNNDIIKIITVPTKQHDGGGNSDRTNLAVAAPHPKLDAFTKYSSNLIRMKELLLLGDNDEQDDGEDDLDYLSSLNKALRYAGISDHGQQIDRNNHGHDDASTSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1E9</accession>
    <name>A0AAD8Y1E9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011720</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042229958" description="Secreted protein" evidence="2">
        <location>
            <begin position="29"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="126"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="189" mass="20078" checksum="B462E807D919A74A" modified="2024-05-29" version="1">MKQHRHLSLSRVATALLLTIVLSYRCSADESSNLRRAATMTGNNDDHVHVAVAAAASSPLGMHSHKYNEEGQFFLPSSSSATAERRTLREQLQRLLKKRQKRKRQPKQPKPPKIVPAGEAFTSTGAKASKAPSSKSPKSSKSKSSKAPSLTPSLAPSASSAPSVSSQPSQVPSKSSAPSESLQPSGKPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1F7</accession>
    <name>A0AAD8Y1F7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011735</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1F7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="284"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="333" mass="34960" checksum="9C84DC9D4982287E" modified="2024-05-29" version="1">MATHSSSTGESFSMPTTSTTSSASSDRHRFNSWALLFLFSTLALTAHETDDSNANAGANKLVTAVSSITLIISAIGSIAHLGFSGLLSSMFVGTLIEGLLALIALALWAGCLPVVMDPRKGLAQMYVGKQSDEVIDYQPIISNANLYFCSWGAAICVLSVFAQYVRERLGGSSRGGSGMGYTNLWYLLGLASVVVVIEGMRFKNQVCVIDGGAETATCGRNTYGLVTGIIGLIVSVIISLFSSFGKDSALVTTVSSFLCAILYTICAGLLTFDKGPATYVGNQYLAAWSGFFLSFAIFGSVVKEFMGVAGGPTSGASANNDGEEDEENEMDTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1R6</accession>
    <name>A0AAD8Y1R6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WRKY19-like zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011741</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1R6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056866">
        <property type="entry name" value="Znf_WRKY19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24906">
        <property type="entry name" value="Zf_WRKY19"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="216" mass="22908" checksum="7B24240E5BAA2DB8" modified="2024-05-29" version="1">MRRSANTTKPAATEDEEDYAALIYQESQRRKAEAAALAADAGKNKKKSSTLKNGATRRTSPRISAAVAGSSTQSVVRLGEAAAATRKRKSSADIHNGDDRAPKKVAKKQYRKIICSADACTKVAQQGGVCVKHGAKVKRCSYEGCNNQVQRGGVCVRHGGKTLCRIEGCTNQVQCQCGGVCIRHGAKIKTYLCSSEGCPNQAVKGGVCVRHGAKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1S5</accession>
    <name>A0AAD8Y1S5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LTD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_011212</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1S5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1260">
        <property type="entry name" value="Lamin Tail domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001322">
        <property type="entry name" value="Lamin_tail_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036415">
        <property type="entry name" value="Lamin_tail_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00932">
        <property type="entry name" value="LTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74853">
        <property type="entry name" value="Lamin A/C globular tail domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51841">
        <property type="entry name" value="LTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LTD" evidence="3">
        <location>
            <begin position="14"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="240"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="143"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1737918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="275" mass="30496" checksum="AE3442C72C0BF09C" modified="2024-05-29" version="1" fragment="single">KPSDAEAGGEEEPSKEKEEAEGKGKGVFISDINYKGVKKGSESDEYVEVTNDSKATVDISGYSVVDINHHGTVKETVGTTFVFPTPTELTPGKTVKVYTNEIHKESGGFTFKSGSAIWNNKGGKGVLMNRAGTEISQFVYISQKQLQTDIANTKTQLKKAKTERQEKNREWRKWRDLNALPMTTREEKIERREIRAKLKIAAKEFTLASKVVTDLKKALKALEGQLEQMKKLGSSCSKMEIHSSDFSDDDSDIESQRCAGEDINVSDISDSESES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y232</accession>
    <name>A0AAD8Y232_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD-dependent oxidoreductase</fullName>
            <ecNumber evidence="8">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_011281</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y232"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006093">
        <property type="entry name" value="Oxy_OxRdtase_FAD_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00862">
        <property type="entry name" value="OX2_COVAL_FAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042106097" evidence="6">
        <location>
            <begin position="21"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="7">
        <location>
            <begin position="147"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1737987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="706" mass="76586" checksum="E9E87CFE17772383" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y290</accession>
    <name>A0AAD8Y290_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rad60/SUMO-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011807</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y290"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048024">
        <property type="term" value="P:regulation of mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022617">
        <property type="entry name" value="Rad60/SUMO-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052225">
        <property type="entry name" value="Ser/Arg_repetitive_matrix"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23148">
        <property type="entry name" value="SERINE/ARGININE REGULATED NUCLEAR MATRIX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23148:SF0">
        <property type="entry name" value="SERINE_ARGININE REPETITIVE MATRIX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11976">
        <property type="entry name" value="Rad60-SLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad60/SUMO-like" evidence="2">
        <location>
            <begin position="19"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="645"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="731"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="843"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="930"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1023"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="304"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="663"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="843"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="855"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="874"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="930"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1023"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1052"/>
            <end position="1127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1134" mass="127617" checksum="F39F7EEADE863C82" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2I5</accession>
    <name>A0AAD8Y2I5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_011283</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 5"/>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2I5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000006">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005818">
        <property type="entry name" value="Histone_H1/H5_H15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43811:SF19">
        <property type="entry name" value="39 KDA FK506-BINDING NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43811">
        <property type="entry name" value="FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00538">
        <property type="entry name" value="Linker_histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51504">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="H15" evidence="7">
        <location>
            <begin position="3"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="6">
        <location>
            <begin position="100"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1737989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="184" mass="19555" checksum="9FED92C375DF54A5" modified="2024-05-29" version="1">MAPPKTIVDKIVYAIRQQPAASANGVSRAAIVKYLSAEFGVDKTKAASKKAFKDGVSKGILIQTGQSFRVKGDTVPEVSEEPKVVIEELKEGKGPPAQSGDTVTVKYEGKLTDGTIFDSAKSFEFTLGAGEVIKGWDQGIAGMKVGGKRKLFVPSKLGYGKRGAAPEIPPNADLQFEVKLKSIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2P3</accession>
    <name>A0AAD8Y2P3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011373</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2P3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1738079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="27" mass="2859" checksum="FD4EFB547400BA5E" modified="2024-05-29" version="1">MTATTSSIITIFSEEDTLAALEATSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y336</accession>
    <name>A0AAD8Y336_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Vacuolar ATPase assembly protein VMA22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010683</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y336"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070072">
        <property type="term" value="P:vacuolar proton-transporting V-type ATPase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040357">
        <property type="entry name" value="Vma22/CCDC115"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31996">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31996:SF2">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="146"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="146"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00093634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="238" mass="26209" checksum="0BB438EEFEBC560A" modified="2024-05-29" version="1">MTATDNNTTPTTTLLTLLHQYSTLHSTASTNFKSTLWNITKARRGRGYQTSGGPLGSSEYSVENVREELEATALIEVVVRLSDGVEPDLVDEHDDDDSNNAVSNKLKGNYSSLDMNTMVLHFDGVEGIKRKSAKAAANINVTTSATTIEERSNNNQEGLRRRKNKGNNNNDESKTTWSEEQPPVESQKALSDPLQLFGVPPPALRVAQSHSRDALAYYVEVANLARQIMTIVQEEEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5B7</accession>
    <name>A0AAD8Y5B7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF3054 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010397</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5B7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021414">
        <property type="entry name" value="DUF3054"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35283">
        <property type="entry name" value="T12C22.21 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35283:SF3">
        <property type="entry name" value="T12C22.21 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11255">
        <property type="entry name" value="DUF3054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041928877" evidence="2">
        <location>
            <begin position="34"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="251" mass="26323" checksum="23B3238F97BE0095" modified="2024-05-29" version="1">MMKSSSLRNRLCPAAASIAALLLVLSALAAISAVDGFAPPIVTQVAGNARTDALFSSPHAAITTTPLLQSKSINLSLKRNSQQGGQRLRTSLFAVEPDSNNDSSIDSSSGLQKIYTPINRPLLAVVDTISLVVFAAIGKSSHSANGDLDIFAVLMTAFPFVTAWLSTSPLTGVYSPDDTSDESNVIVSTGMKVVKGWAIAVPLGIALRGVIKGYVPPTPFIIVTLISTLVILVGVRVLFAIAEDIFVEMVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y713</accession>
    <name>A0AAD8Y713_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008797</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y713"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="2">
        <location>
            <begin position="88"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="338" mass="37567" checksum="21A6CBEBC94AAD38" modified="2024-05-29" version="1">MTIAAATDVLMAPTIASTSTDESARKRRRVSDDVLIPDEITSESTQDSPVVPAAAPIVTVRRTKGAKRPQMKYDPSVPMTKEETSVWRREQRRKRNRESAAACRRRQRDRISELEVEVSDWRAKFDEALNKLKDLEGEEAVAHFEALRNLAPPTRCSTPENELAAPEDTTSMSIPDMDCSHIITPNCPKFVPLINTSEEDDIRFPVLEVSADVTADKVNTSLDSLDSRVEKQQYLKEMITRPAKSRLLTSRRRIAMKITGTVSATPLDNIESVCDDLLQVVPESCLSLTELKTMPFPETCPSLVTASTSKNSTPVTTDGESDEDSDLGEFLADAVQWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7E0</accession>
    <name>A0AAD8Y7E0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008185</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7E0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="377" mass="42661" checksum="A8AE57D1A27D1855" modified="2024-05-29" version="1">MSTATKCNSGNKRNSDGSLRAENTTICLVDIPVEPLAHVASFLSATSQAIFGLAVAAVNDKILNKNSFAIVGDQWDSLDFTEIEKELAARLTDDDIKAVLWCIDAANKVKRLSLAHCVNITGSCLEQLRGSQIIEQIDLSLVGRHEDPVLIEPWHPPRKDESLVLPFVPPISCENVLPILDSIIVSEQCSLQHLQFPKAWRTNYPSEKDSNWSSWSRWNYDTSFKPDPTFVRFLMRYNQMLMNRGISCVKCSHNLHSSGYQLVGSSVSDRKSFYTFGNQNHTCSQCMKHYCYRCGIQDSNEEFRNRRDGIGDFHLERCNVCEREQCVECSGMYRCETCPSSTTFCMNCKESTKCSLCSNRECNDCDLSRCESCKKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7W5</accession>
    <name>A0AAD8Y7W5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">KOW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008481</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7W5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KOW" evidence="2">
        <location>
            <begin position="199"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="2">
        <location>
            <begin position="269"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="2">
        <location>
            <begin position="346"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="410" mass="45200" checksum="A16ED77EE67EBCEE" modified="2024-05-29" version="1">MSKRSIRRRSVRLAKKVWNVVLNNNKDQRKSRSSVRSTKISDDFSNDDDNDGGHTLSVSSNDSSQYEPQNADVDLVIERNVEEDVDVESCCMSQSIDVENHDAIEENNHDVTELHVHDDTGSVTEKDNSSLSVTAPGHLDVSAHEDGDTSKEGSKAESEELLEILMDNTSCADEGTGTVSQSQGIDQQLCQEEFKEENAFAEGAEVHIITGTNKGKRGIISRVTSKCAFISIDGFDKDVRKTKSSEFLEIANQKEICCKQHHNSDPQECFLEGNLVQIKEGAHKGCQGIISRTTAKCVFITIRGLSKEIRKKKSAEFLEILNDGTDCAPQDIDQQACAEESSEVNDFVVGMQVRIVKGNHLGNCGVISRLTSKCAFVSIEGVAKDIRKTKSDQFLQIVKLTDEQPHESGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7W9</accession>
    <name>A0AAD8Y7W9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase-like protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_008903</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. PrmA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7W9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008988">
        <property type="term" value="F:rRNA (adenine-N6-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051720">
        <property type="entry name" value="rRNA_MeTrfase/Polyamine_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23290">
        <property type="entry name" value="RRNA N6-ADENOSINE-METHYLTRANSFERASE METTL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23290:SF0">
        <property type="entry name" value="RRNA N6-ADENOSINE-METHYLTRANSFERASE METTL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase small" evidence="4">
        <location>
            <begin position="34"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="126"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="285"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="147"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="285"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00041374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1740808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="309" mass="33742" checksum="60BF5D66B38E1C99" modified="2024-05-29" version="1">MKQKHLESCLSSIPNRVFPDPKIQLEQYPTSVNLAASIVLTALAKGDAGKGRTILDLGCGTGNLGLAFAIVKSDFVYLVDCDSDALDLARENVEMLEEEELIGSCSEDEDGCCMGVELIMAKLKYDPPKKNQSGGGGRGGKGRGRGRGGGGRGKGGRGSASSTQPNELLLLDPKLDNRDDGIPLPSKMVDTVITNPPFGTKNNEGIDVQFLKTAIRLARRSVYSFHKTSTRPFLVKLLRDKWGLNVEVVAEMKFEIPNMYKFHKQKCVDVEVDLIRVFWEEEDTIEDKDASEEEESEGEEMPLGVCGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8U7</accession>
    <name>A0AAD8Y8U7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Bifunctional lysine-specific demethylase and histidyl-hydroxylase</fullName>
            <ecNumber evidence="3">1.14.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_008725</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="3">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ROX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8U7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051864">
        <property type="term" value="F:histone H3K36 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032453">
        <property type="term" value="F:histone H3K4 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04508">
        <property type="entry name" value="Tudor_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039994">
        <property type="entry name" value="NO66-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13096">
        <property type="entry name" value="MINA53 MYC INDUCED NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13096:SF8">
        <property type="entry name" value="RIBOSOMAL OXYGENASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08007">
        <property type="entry name" value="JmjC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2 3" id="KW-0408">Iron</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042176028" description="Bifunctional lysine-specific demethylase and histidyl-hydroxylase" evidence="4">
        <location>
            <begin position="33"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="domain" description="JmjC" evidence="5">
        <location>
            <begin position="227"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1740630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="666" mass="73206" checksum="EE4CAEEF217A610D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y933</accession>
    <name>A0AAD8Y933_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Long-chain fatty acid CoA synthetase</fullName>
            <ecNumber evidence="1">6.2.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_007496</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.3" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y933"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.38.10">
        <property type="entry name" value="Luciferase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052987">
        <property type="entry name" value="Chloroplast_AMP-bd_Enzymes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43813">
        <property type="entry name" value="ACYL-ACTIVATING ENZYME 16, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43813:SF1">
        <property type="entry name" value="ACYL-ACTIVATING ENZYME 16, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23562">
        <property type="entry name" value="AMP-binding_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1741923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="143" mass="15908" checksum="4AF8DD9E2F6B1B50" modified="2024-05-29" version="1">MKGYYKNKEATEKAIDKFGWFNTEDLGYINPATGDLFISGRAKDTIVLSNGENIEPQPIEDAILSSSDLVEQVMLLGQDEKHLRTIAVVNPDALAKAGLLDEELAAGLMKDYETVNDPKCTEEDCVQAPRRGIESHPIKRNHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y973</accession>
    <name>A0AAD8Y973_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007556</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y973"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="488"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="292"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="490"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="585" mass="65335" checksum="25503787285A3DC3" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9B9</accession>
    <name>A0AAD8Y9B9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_007490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9B9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1741917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="324" mass="35029" checksum="65E516404B712A40" modified="2024-05-29" version="1">MMSASSSPTTSSSHRPTVKALLVLAAVACLGIIARHNLRGDISSQPLRLSTSYNDNYELLDTSGPLDRLNTKNVAEQQTSESNNDNEYFVFLQKFPLQNTWQMIFHTEVVVCPRNSFHNDADFLSTLDQLAETLSPTTDAPSNDSTKVPFVKVPEEKWTKQSNSKCVQLGYGGAACPSACCGSPHGNDNTNYALNSRHAVIGNAMGDAKQLFLYGVSDSINGMDAYRAVCGGSTTKTMPTTCVSKWAGTDYNPLTNNCNTFTSTILKCVYGLSDAKPNLGISDMVNVACPMEKRDDGMDVQQCLIPVMTTSLSDAADEVMADGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9L7</accession>
    <name>A0AAD8Y9L7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007779</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9L7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="404" mass="45914" checksum="A0F374B04BA6F25E" modified="2024-05-29" version="1">MNIRRDTADHIISIIVKHRRALFIICAAFSLAVSLFNDALYLLGGPDAISTKEKPFVMCDRPTPLNYAIHPKMTQQVTYSGEPFVPRWPTQKKLLLLRKDDYLFGHIGNQINSLLHAYDYARDHQLELGTTFHGWVIEAIQFMGYESNDNKELRNEIRNELGITIIRNSTDLVGYDEVIQLSAKDLYFYKSPGDNWESNMNFHIGILRRIFLRYNRALGYAHHGLRAINVCRTIDDLFHGSGSSMKYTVIHSRFMEGRAQFKLNQLAKTSGLTPKGALEMSPKYIRMILKPLGMLEHPIVLFSDGELPSVEEGLLRDPVIGPKLIVLGNKTSLTGPDTALAMLSDVYIGNPASVTSGYIARSRHALGYNEEQTYMFRKEHKDNWISVCNAKCIFNPWVMSTNLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9Z5</accession>
    <name>A0AAD8Y9Z5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007089</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9Z5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861:SF1">
        <property type="entry name" value="TRANS-ACONITATE 2-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861">
        <property type="entry name" value="TRANS-ACONITATE 2-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="1">
        <location>
            <begin position="52"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="208" mass="22722" checksum="FA2FD52E1ADE1A22" modified="2024-05-29" version="1">MGASLAKQMRSPEPGTCMGWMAQKIMSSGSGVDSVDAVSVLKLEVEAPTIVELGPGAGYAMRSMISSFSPSRFYGIEISDAFRKGLSEDAELKELIEKKVLSLHGDDAKDLGFIPDNSVDLIFAHNVIYFLDPLDVYLKEAYRILKPGGQAVFGVKQVAQAMDQSIYINTDWDVCLEEMKKAGFETAEQKEPRLEGAAAYIPLVCTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAZ2</accession>
    <name>A0AAD8YAZ2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006829</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAZ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="239" mass="25930" checksum="14BB52F606FAB57C" modified="2024-05-29" version="1">MPELTEADVVALAEIDYASIGNAPPLSVRDERLSESSVTERGGRQFSVATPISEMDSIDENSILRGSPFRSIIDEDSESNISIPEQESRMSNESENTSVEVMPSDRSDNTGSHNSIEVMLSEHDNDSLHDGRRVSDIDDMASSTSIEASPSVDSDNNVGDVKGSDRLAMYGATSEGDDGIMYYNGHHPSLSYDHDEESAPLILPQISASPLQSSHPHGGEKSEHAVQIRRNESRLATEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCN1</accession>
    <name>A0AAD8YCN1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcription initiation factor TFIID subunit 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_005755</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCN1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07981">
        <property type="entry name" value="HFD_TAF12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037794">
        <property type="entry name" value="TAF12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003228">
        <property type="entry name" value="TFIID_TAF12_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12264">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12264:SF21">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03847">
        <property type="entry name" value="TFIID_20kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription initiation factor TFIID subunit 12" evidence="7">
        <location>
            <begin position="245"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="141"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="366"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="15"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="199"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="216"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="378"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1743134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="388" mass="39663" checksum="D166900052E1A148" modified="2024-05-29" version="1">MPPKGKDISAMSAPPAVPAVPPAAAPAPAAPVTTIAAAKKGKDFARMASAASTQQMRAAPAPIPTPQTQNNAPPVAAASGGITMPGGRPKGKDLSRMGGGPPPPVPVPIPVNHAAAPYSVPPGTAPPVQVPAPNNMEQRHEIARRKAYGLNATNNPNMRPAAPIGYHQSYSQSAQPLAQHRPLVPNTSQPPQPVDTRVAKAKQPTKRPSHAESRLSKSTTASATSSSAKSDDNYGNAALAPAIGEKLQKLCHSIDPSYTLDSEVQERLVEMVDSFVDKVTKDAVRLARHRGSSNLDVVDVALALKKGYNISVPGLGPPSAARGKGQSVVAMSGVGGTAATGGQYGQYTGGNMKGGWLFADKVNAPAEGGSAKKKRKTSNAAAATSAAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD79</accession>
    <name>A0AAD8YD79_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Calcium-dependent phosphate channel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_006055</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CSC1 (TC 1.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD79"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032880">
        <property type="entry name" value="CSC1/OSCA1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF5">
        <property type="entry name" value="RE44586P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13967">
        <property type="entry name" value="RSN1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="567"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="609"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="699"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="766"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="816"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like N-terminal transmembrane" evidence="10">
        <location>
            <begin position="82"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="11">
        <location>
            <begin position="276"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="9">
        <location>
            <begin position="561"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="112"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="380"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1743434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="945" mass="106144" checksum="FB0255ECCCD89020" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YE14</accession>
    <name>A0AAD8YE14_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YE14"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="210" mass="23292" checksum="35189C956C6B4BEC" modified="2024-05-29" version="1">MNKCITPEPTPTISAPLSSSSQDEQPSSAAAAAVITMASPSRRQTRKRPLIEACEPNDDDTQSTSRPISATSSSRKRQRSKKESTVRFASVPHQTHVVPRWTKDEATSSWYSKRDLFTFRRQESVDAAVLRSLIQTATTIDTLPQETAVYRGLERLLSSQIACEISDRRKRCVMSVLVAQHRGLDMELIAQVSKNFTEKAAAWALTLGSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFB8</accession>
    <name>A0AAD8YFB8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_003400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFB8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.95.10">
        <property type="entry name" value="Cytochrome c oxidase, subunit VIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001349">
        <property type="entry name" value="Cyt_c_oxidase_su6a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036418">
        <property type="entry name" value="Cyt_c_oxidase_su6a_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11504">
        <property type="entry name" value="CYTOCHROME C OXIDASE POLYPEPTIDE VIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11504:SF0">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81411">
        <property type="entry name" value="Mitochondrial cytochrome c oxidase subunit VIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1745476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="143" mass="16221" checksum="74FDEF26721572A6" modified="2024-05-29" version="1">MFAARTLARTAARQGTQAVQRRSNQTVPRLGTQAEMEAEAIAHLRARVRRQKEIMDATEHSAEEELAEMWKWVKISAVVATPVCILSIIKDVLFVPHAHRQEGPLPDYMSIQVKEFPWECETCALFDLECWKKCRAEQAAEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFX3</accession>
    <name>A0AAD8YFX3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Purple acid phosphatase</fullName>
            <ecNumber evidence="5">3.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_003291</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.-.-.-" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFX3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00839">
        <property type="entry name" value="MPP_PAPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041792">
        <property type="entry name" value="MPP_PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039331">
        <property type="entry name" value="PAPs-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025733">
        <property type="entry name" value="PAPs_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22953">
        <property type="entry name" value="ACID PHOSPHATASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22953:SF153">
        <property type="entry name" value="PURPLE ACID PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14008">
        <property type="entry name" value="Metallophos_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="3">
        <location>
            <begin position="120"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="Purple acid phosphatase C-terminal" evidence="4">
        <location>
            <begin position="362"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1745367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="464" mass="53429" checksum="1CB51B3A55A5795F" modified="2024-05-29" version="1">MTVSFSISPACIDETSTVGAVRVGDVMIEGDPNDVVSYNASRSDHNHYYSDLYYHIEIDDLQPGRKYSYQCLLLQKEEPSIQQYLRQDREVLNERIISRSNISTFHTPPAPGQWPQDRSIKFAVMGDLATKPHSRETIWHLDRDKSIDCILLAGDISYANNHHHIWDEWMDMMSAHDFFSSTPVQIALGNHDLDTVHRSGPIEAIDGSLEIGLAYESRFRMPQIQPPVRELASLNLFRRNGQPNDFLPYEFGNAYYSFTFGPSKHIVLSSYTSFREGSLQYEWLLSELQSVDRSATPWLIVMLHCPLYTTFQTHHKELFTTEAQAILEPLFVEYTVNFVVAGHIHAYMRTHPMAFSRRDPRGPVHIIQGNGGRQANDLYYSDAAEEWVDVRDHSMYGYGVLDLFNNTHAMWKWVKTGFNAEGEGGIHDQRFDADLNLHDEIWITNQLYVEEMGVNENVELDLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YG46</accession>
    <name>A0AAD8YG46_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cupin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_004240</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YG46"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF98">
        <property type="entry name" value="CUPIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042118167" evidence="2">
        <location>
            <begin position="19"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="JmjC" evidence="3">
        <location>
            <begin position="298"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1744949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="474" mass="54378" checksum="FD44E9ABABD2F801" modified="2024-05-29" version="1">MFHCLWVVLLAIKVFVKSRSSPSRYGIDYERYARGNTLRDALRGGNRQKQSSQQQSFGENGSRYFDPRQFPPLPSESSERYDGEGPRRFRGLGDDEWVADAGSKSNGPKVDYTKHKYSYPELMFEPPNDGSYPPLVDMSKIFEFWGQDDLDSPPEIIPEVLQHFDYQNPHEVAAAEKYRDLELPFKVYNVPEVKAAGIKWTDEYVADNFNDAGDDDTPRSYGNAQQSVDSFFAFYYPERWDVDLLGPSPSLDIDWTYDKWAQHAVYADEVSLSPNEKHYYWQSGVTREERLKKRKHWTFVSRDLPSFSSPEPTFFGFNPPAQKGIQCRFGERGVTAATHYDGGRNMIAMMTGAKRYILSPPNACKKLGIVSSRHHPSFRHSMLNFGRVTLLDKKDTGVKMSDREREWLRIAGSAQTLSTVLKAGEVLYVPSHWFHYIVSLQKSAQCNTRSGIHEDGNRNFGGMRDVRQCTLDRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGI2</accession>
    <name>A0AAD8YGI2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGI2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="281" mass="30303" checksum="2935C9A5BDC569B1" modified="2024-05-29" version="1">MSSSEDDDIPLSSLGKGGKRSRIKDDDSSEAEFDDEASDEPADEEDIDDFVVEDEEGDDDEDVDYDSDDSDDDIPISALKSPTTKKKAAKKPAAKSKATKAKAAPKKKATTAKKKKPATTKKTASKSAAGASSSYVSASTELYANSDKGTLIQSLLARWWYVYTWPDPATMTSTPKGYDALDGFPGVYICTSGENVGKFKDDRDPKTAPTFQNLSKKTSAELRDDLLKAIEKQMAALIKAEGGGTKTEKDLKALQKWATKLNCSKADKDAMKVLKAAKLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGR0</accession>
    <name>A0AAD8YGR0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alkaline phosphatase D family protein</fullName>
            <ecNumber evidence="3">3.1.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004147</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.1" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGR0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="entry name" value="PhoD-like phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33987">
        <property type="entry name" value="CALCINEURIN-LIKE METALLO-PHOSPHOESTERASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33987:SF1">
        <property type="entry name" value="CALCINEURIN-LIKE METALLO-PHOSPHOESTERASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09423">
        <property type="entry name" value="PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="385"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="420"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD-like phosphatase metallophosphatase" evidence="2">
        <location>
            <begin position="19"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="505" mass="55438" checksum="ACD3E4526E3A1794" modified="2024-05-29" version="1">MNFTVALGSCSLTGSRSQIFQSILELEPQLFINLGDFHYEDLVTLDVNERLEAYDKVMGSSSQRSLYMRTIFSYIWDDHDWLANNDDGSNIDAGNVAKQGYSLGIPHYNLGPIETQTSTDEGTAAKYQAFTIGTVRFIILDLRSESRKSTASYGGKVYSDEQKEWLFSELSQADNYDYVVLASSRPWTSPDKIGSDGWGGFVSDRDELSSFIASTIGAGPKNLFVISGDNHMVAFDDGSSTDYSGQSEFPGGFPLLHSGPLSNYGPGGAKNIFKPREHRFTEGCMAVSSELNYQFSTIEFDLPQDTAESGCLRIKGYKEGSSSDNIIFEKELCGEIMRDGSAEQDTCKMKSFTAPTAAMLLVALILTMVPGMLILYFLGRNRWVLALIYFGIGILFYGITIAASVVGALCFGERAKALDVSAVLLCQTAIGLAFVYIAIRRYCSSQYGKKDIAVPEKIAAVSGEDDSAKESVFALANDGFKNLEEKKQTEIEVQPNESEEIEVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGX2</accession>
    <name>A0AAD8YGX2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fibronectin type-III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003831</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33683">
        <property type="entry name" value="1, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33683:SF46">
        <property type="entry name" value="SUSHI DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042137223" description="Fibronectin type-III domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="1426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="776"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1004"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1148"/>
            <end position="1236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1261"/>
            <end position="1285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="782"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1004"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1148"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1170"/>
            <end position="1188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1426" mass="152494" checksum="55AF650EE33CE21F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHG2</accession>
    <name>A0AAD8YHG2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Aldehyde dehydrogenase</fullName>
            <ecNumber evidence="9">1.2.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_002695</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHG2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006081">
        <property type="term" value="P:aldehyde metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07087">
        <property type="entry name" value="ALDH_F3-13-14_CALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012394">
        <property type="entry name" value="Aldehyde_DH_NAD(P)"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570:SF16">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042295140" evidence="7">
        <location>
            <begin position="25"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="583"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="8">
        <location>
            <begin position="90"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="48"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="52"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1746088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="607" mass="66435" checksum="FACF2C64C60AA866" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIG1</accession>
    <name>A0AAD8YIG1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_002500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIG1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000183">
        <property type="entry name" value="ABC transporter ATP-binding protein yjjK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000011">
        <property type="entry name" value="Putative ABC transporter ATP-binding component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051309">
        <property type="entry name" value="ABCF_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42855">
        <property type="entry name" value="ABC TRANSPORTER ATP-BINDING SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42855:SF1">
        <property type="entry name" value="ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="8" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="2" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="15"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="294"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1747156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="513" mass="57312" checksum="0EBEA44A0C764B81" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKT8</accession>
    <name>A0AAD8YKT8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_002456</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKT8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="171"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="79"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1747112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="317" mass="36570" checksum="E6097C3BE92C2670" modified="2024-05-29" version="1">MSSIMTKDEYGRAFCKEHNRDICHDCGLDFRDMNRMAEEDAGLKKKRSEVEQTAEMIAVCLYALNGMERMRPRPNEAIFENNRQRLKEYQDKLQSLKDAGEEGVDEALRKACEKQNVSEIQMRGLMQAWSKQNHGKTTMEIGGEETQKLYEQFIAPPVKTSSKPKAEKWTCDYCNKTSIKKLPMCTRCKTVSYCNRECQVAAWKAHKTTCVPIDKEPKSLPQTWAQVESHGDSRVEGKTLEVRAILDESMTRQIFQCKDRVGVVKRIAAYTNDRRIPGLQQGSVIRWKNPRFYYFMDGSSGARIEEEDLPNLKISNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLN2</accession>
    <name>A0AAD8YLN2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_001747</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLN2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000011">
        <property type="entry name" value="Putative ABC transporter ATP-binding component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF133">
        <property type="entry name" value="ABC TRANSPORTER FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042225374" evidence="4">
        <location>
            <begin position="20"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="78"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="409"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1747784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="636" mass="68954" checksum="238B5FBDFB693A35" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YN81</accession>
    <name>A0AAD8YN81_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YN81"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="441"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="521"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="653"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="565"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="605"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="653"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="668"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="681" mass="71778" checksum="233B6F6526563EA4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4E8</accession>
    <name>A0AAD9D4E8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Adenylate kinase</fullName>
            <ecNumber evidence="8">2.7.4.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_015644</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000046">
        <property type="protein sequence ID" value="KAK1733601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4E8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:AMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="3 6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6 8" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="140"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="238"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="344"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1733601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="584" mass="64877" checksum="0B05F27C090032FE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4T0</accession>
    <name>A0AAD9D4T0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Fucoxanthin-chlorophyll a-c binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">QTG54_016468</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated. Energy is transferred from the carotenoid and chlorophyll C (or B) to chlorophyll A and the photosynthetic reaction centers where it is used to synthesize ATP and reducing power.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast thylakoid membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fucoxanthin chlorophyll protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4T0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030076">
        <property type="term" value="C:light-harvesting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3460.10:FF:000011">
        <property type="entry name" value="Fucoxanthin chlorophyll a/c protein 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 15" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="5" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="10" id="KW-0157">Chromophore</keyword>
    <keyword evidence="13" id="KW-0437">Light-harvesting polypeptide</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="14" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042290758" evidence="16">
        <location>
            <begin position="16"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1732930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="203" mass="21971" checksum="3E0EEAE9ECE59BAE" modified="2024-05-29" version="1">MKSVIFAAAVASAAAFAPAQTGKATTALNAFENELGVQPPLGFFDPLGLLDDADQERFDRLRFVEIKHGRISQLAFLGNIITRAGVHLGGNIDYSGDSFDSYPNGLAALFGPDSVPDKGTVQIFCFIGLLELFVMKDIEGTGNEFVGDFRNGYIDFGWDKFDEETKLQKRAIELNNGRAAMMGILGLMMHEQLGGSIPIVGEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D546</accession>
    <name>A0AAD9D546_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D546"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="250" mass="27286" checksum="E71B06E2178BA837" modified="2024-05-29" version="1">MVVSLPWTDHAGNAGHYTGEVNTLIQPHGSGAIQYDCGTVVKGSWNNGNPTARTSPVVEKEVIKKAVAVEAAKTDGAAATASGNAPTSRKKGDEKKSSSKPSNLPTKTKSSRKKSRGHSNNMAMEDKLSTTNATKSTSLTQPTAQPSLDRLSELDGPPNFDLVDTLNSTKYQIIESNPTKALQLIHQLRIHDFAWILRSSREWTYAIIADFPVESGEEVSIRFVIDKFGSTKTLKMKHWAKCIRLVDKSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5U2</accession>
    <name>A0AAD9D5U2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_015251</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1733993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5U2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1733993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="670" mass="74871" checksum="FDBD05BAF2E4D3E8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6R5</accession>
    <name>A0AAD9D6R5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6R5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="109" mass="11726" checksum="68BAB3608FEC8FEF" modified="2024-05-29" version="1" fragment="single">MICLSDLPTGALAHVSSYLAAPSRALFAVALKFEDVDSSAAVIGCRWVALDFGDIEKDLVTKLSDDDIRGVLLSIDAVNNLRSLRLTNCINITGVGLDPLRASRIIRQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6T9</accession>
    <name>A0AAD9D6T9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014096</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6T9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="318" mass="36312" checksum="F72218866C6FBB5D" modified="2024-05-29" version="1">MKFNMRRNQQRHDVPPRRVRKDRSLLDEPRINEISDQLLKREIRDVVINTAHSLKAAASFKTTAFHELGQEIGEELTEFQLSTTKSFYDLKEHLEDHFTVVNETETAMPSLFHNDTDKVCDARDDDMSLTDGGESRFDAEDTVEQNSLDTDDDDTAFVSVDLSKKSTGVDASTIAGDLTETDADESVEDDGEKQAMENLTGTFSAFSQCLGEINCADINCADITFGTGLFDDDNNHNNHTENHSNHDNNTKNNNYDQNNKVHDDDTASVLVDKTIDWSKIVKQASTERMYAPKACEKKEKKEKKWKKMKMKIFRRRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7R9</accession>
    <name>A0AAD9D7R9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013156</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7R9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="344" mass="37918" checksum="D720F48434FBA7F2" modified="2024-05-29" version="1">MHSLVLSQRDAESQRRHAALQFQQDALVLLSKIESSFSSLSTNIESSQSNTVDVATESHKNGQQFLAETQQLLSEISENVVCVTNSIKTLITGDEGIVSSVQTSSDSVLLHMRGSSEAFVKGEVEMEKSCESMRNRLNESSKALDERSSSIQSSTNQTLQHFEEKVVESKNAISHLVLRMKSLITNLSESKAEKVKELDSLVEQWRDQSIGNSKSLHDMTSSSMNTYKASIDEFESGMRGHEEISKSLEDQRSFVNSHGSAHVQSIGQQSSILQAHCDNLKQSHQTQTDLRNEVMTSIMSGVQALVAAEMQKLASAETDNFKVLEKGSSDLTGINQVMSQSLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7Y8</accession>
    <name>A0AAD9D7Y8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cysteine and histidine-rich domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_013275</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7Y8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1130.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007051">
        <property type="entry name" value="CHORD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039790">
        <property type="entry name" value="CHRD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46983:SF3">
        <property type="entry name" value="CHPADIPLOID STATE MAINTENANCE PROTEIN CHPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46983">
        <property type="entry name" value="CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04968">
        <property type="entry name" value="CHORD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51401">
        <property type="entry name" value="CHORD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CHORD" evidence="4">
        <location>
            <begin position="133"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1736139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="309" mass="34186" checksum="7ACB36EFB3A5B89C" modified="2024-05-29" version="1">MKVFLRYEDNEDESKHKTLKITLPKSWKTGPSSRLLDQFVESYNGGNEGQSNPLESAGMHLALRRSSATAANDDTATTSLEDVPSDGIIIETIADRDDVFVCHGPSRTVEEINAERQAKLDQEKEAQKNLSKCVHFGCNQRFPKGGPYPDCKYHTGPPVFHETAKFWSCCPNKKAYDWDGFQTLPACQQGKCTDVKDEENNQKQFLGGCDLREEMNGPKLKSIDDFNASAAAGGSEGAPVLERLRSVLGELGVENELFDQVLEGVKKEEMTKNGLQEDDAKVVDEATKTLGLKLKKSLKAIAVEQLRIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8L7</accession>
    <name>A0AAD9D8L7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sulfotransferase family protein</fullName>
            <ecNumber evidence="6">2.8.2.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_012305</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfotransferase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.2.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8L7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11783">
        <property type="entry name" value="SULFOTRANSFERASE SULT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfotransferase" evidence="5">
        <location>
            <begin position="120"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1736860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="401" mass="45164" checksum="6760C8D968A77D40" modified="2024-05-29" version="1">MLSHLRSKDQNESIDSVSADNSGDGSLRLPALRYCCLMTSLTQRQYILGITVAILAAVYAALPTLMAALLKHMFTAPNQVPWTGGGHLRLIDIDGMPAQALYSVERAHELVSSSFQHKQGDVWVASYVKSGTTWTIGILAALVGHPAAEYAGNLQKVTRLFCPQPELPDLGFGDDGFGHSMEQLNDWSGMDIGRNNRNYRCFKSHWPSKDHVVSNGKSKFIYVLRNAQDQLISHWNQVYGMGFHYGTEDMTFEGGWDDFVQDWLDGNVENGSYFDHVASWFKRVDEPDVLLVRFEELKRNPSRVIEQIAAFIGMDDVTPTKIQNVMDLTSFDRMKLADEQDMGLRFMRWLGVLRRAHVRQGEVGSADGSRLTFSTEQLAALESLYKEKLQPLGVPREWIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D909</accession>
    <name>A0AAD9D909_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D909"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042006865" evidence="1">
        <location>
            <begin position="21"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="145" mass="15387" checksum="EA6151FDF88D583C" modified="2024-05-29" version="1">MKFIALTAFALLASISYAEANDEPSSALRGSWSSEVEEMLRSTRNGSAATCVKDCECPGGGCTFEKCVNDCECDGGGCSMPVCVTGCECDGGNCDMPACKYDCECDGGNCKMNACTNDCDCDARNCEMKSCKYDCDSFDFDVAQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D917</accession>
    <name>A0AAD9D917_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CBS domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_012146</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D917"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051257">
        <property type="entry name" value="Diverse_CBS-Domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43080">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN CBSX3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43080:SF29">
        <property type="entry name" value="OS02G0818000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="3">
        <location>
            <begin position="7"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="3">
        <location>
            <begin position="71"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1737279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="147" mass="16319" checksum="E72F6D3142C3F5A5" modified="2024-05-29" version="1">MFVSGFMVPIKDVLKCEASSTVKDVLNLMMNWQVSSLVIVLEDKPTGIITKTDMCWCYQNGIALETQIGDVMPWTAGLKKILVTADKDTAAKFFEKHNVHHALVVDSNDKPVGLISALDIAKEVAKDSRAWPYNRHEDGKAHPIDAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9B2</accession>
    <name>A0AAD9D9B2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_011881</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9B2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="433"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="492"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="525"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="832"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="904"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="928"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="110"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="33"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="274"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1737595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1214" mass="136811" checksum="974BFEADC745D8F2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9R9</accession>
    <name>A0AAD9D9R9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">2Fe-2S ferredoxin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_011277</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9R9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140647">
        <property type="term" value="P:P450-containing electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001055">
        <property type="entry name" value="Adrenodoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23426:SF65">
        <property type="entry name" value="FERREDOXIN-2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23426">
        <property type="entry name" value="FERREDOXIN/ADRENODOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1737983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="292" mass="30316" checksum="C1DE88C8BCEFEA6A" modified="2024-05-29" version="1">MSRSSTSYIAIVAAYSAAASMHTSHAFVPSASSSSCVRQSAQASFSIINTATTTPSTTSLFMSSTPATTTNTLTLQLEKPLGLILEESDSTIPNSGVIVTQVNEGGSAFASPSADKLSNAKITKVMETDVSAMSFDDVMDVIVGAPSPLEVEFALAAGVVVESAAVVAGEGEAAAVVAAEEYEIGTTVTIQVEQPDKPSITLEGKVGDNLRKTLLANKDIELYRGLKKKLGNCGGGGQCGFCAVEFKDDSESGVWGERSEYEDTRIGRKAGTEGHRLACMNNIVGPATVKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAF8</accession>
    <name>A0AAD9DAF8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010598</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAF8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36971:SF1">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36971">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="334" mass="38001" checksum="9904A15632D755FF" modified="2024-05-29" version="1">MMSRQCVFIDNKNGAPSLPPPAPLPSLIPYNEGSIRALSRRNRVYVYRDFLLSKFPHMTSSSDTTCNILDVAGGRGDLSWILHNIDGINSIIADPRIPNHKSLIKSTEFLLAHPEEAAVRAVEGVVTHQPLAKLLPRLIENNNCNGQTHLSTPFHLRMHVDDNLVETLKRVFSSDEHLDDERMGIWDEYWQQETCRIEFNKVVYGGTPSADQSQPQKKEVGDAQKRKQQITNSRNAYDTIQSLDYIAGFHPDQATEAAIDLALFLKIPWSVVPCCVFPREFPNRQINDSRVKNHSQLIEYLCTKHEKIRKETLSFVETATAKNVVLYMLSEDYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBI4</accession>
    <name>A0AAD9DBI4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein disulfide isomerase family protein</fullName>
            <ecNumber evidence="6">5.3.4.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_009482</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBI4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051063">
        <property type="entry name" value="PDI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45672">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45672:SF3">
        <property type="entry name" value="THIOREDOXIN DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041939029" evidence="4">
        <location>
            <begin position="19"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="149"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1739723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="218" mass="23656" checksum="1D5A82C0819AC792" modified="2024-05-29" version="1">MMKQAAFFLALAASSASALELSPDNFAAETDGKSVLLKFFAPWCGHCKKLKPDWDKLMADFEGSATQLVADVDCTAGGKDLCDANGVRGYPTIKWGDPSDLQDYQGGRTYDDLKKFAEENLKPMCSVKNIDLCDDAKKADIKKYQDMSAEDLDAAIATEEKKLEDAEAEFKAEVQQLQESYSALSTEKDEKIAAVKNSGLGLMKAVKNSKPAGGSDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DC84</accession>
    <name>A0AAD9DC84_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mitochondrial fission process protein 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Mitochondrial 18 kDa protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_008734</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MTFP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DC84"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019560">
        <property type="entry name" value="Mitochondrial_18_kDa_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11001">
        <property type="entry name" value="MITOCHONDRIAL FISSION PROCESS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11001:SF2">
        <property type="entry name" value="MITOCHONDRIAL FISSION PROCESS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10558">
        <property type="entry name" value="MTP18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1740639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="184" mass="20325" checksum="3BEF5F5ADB641BC6" modified="2024-05-29" version="1">MTKHPMATHLHQDAPKTDDEQKSGNYNIFRDSLLRYCGYANEVGESFRYQYPKFVAPSYALAFGYCLADSISAGYQELYVKEDGGNEGTSSKYDTRSNETRAAIAFFDTLLWQSLASVAIPGGVINTIVRATRFTVARTAGLPLAVTTWAPTVMGLGSIPFIIHPIDECVDFALDNSTRKFLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCE6</accession>
    <name>A0AAD9DCE6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DNA-directed RNA polymerase subunit</fullName>
            <ecNumber evidence="14">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">QTG54_008718</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="14"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02584">
        <property type="entry name" value="RNAP_II_Rpb1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02733">
        <property type="entry name" value="RNAP_II_RPB1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.40.20:FF:000019">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.30:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.390:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.274.100:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.180">
        <property type="entry name" value="RNA polymerase ii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="entry name" value="RNA polymerase II, clamp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="entry name" value="RNA polymerase Rpb1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000684">
        <property type="entry name" value="RNA_pol_II_repeat_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007075">
        <property type="entry name" value="RNA_pol_Rpb1_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007073">
        <property type="entry name" value="RNA_pol_Rpb1_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038593">
        <property type="entry name" value="RNA_pol_Rpb1_7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006336">
        <property type="entry name" value="PRK08566.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376:SF37">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04992">
        <property type="entry name" value="RNA_pol_Rpb1_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04990">
        <property type="entry name" value="RNA_pol_Rpb1_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05001">
        <property type="entry name" value="RNA_pol_Rpb1_R"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00115">
        <property type="entry name" value="RNA_POL_II_REPEAT"/>
        <property type="match status" value="15"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 14 17" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 14 17" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="12 14" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 14 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase N-terminal" evidence="16">
        <location>
            <begin position="236"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1576"/>
            <end position="1783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1576"/>
            <end position="1775"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1740623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1783" mass="196032" checksum="F17F5E465946E7DD" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCG3</accession>
    <name>A0AAD9DCG3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCG3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="156" mass="17402" checksum="0B1108969B03AD8C" modified="2024-05-29" version="1">MNRFLYGKTIDSNNIHNIKATTFPHALKMANRASSDEVPSNILERANDIWRRQHPTENFGLSYKSPDPSTYYTQQFGRDICFATGSAGLEAISLLGDGPLIKSSRNNTCYDALNLFTNCTDTNAFRRINEGNAESSQPTMLTHVPTYAHSPENLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DD93</accession>
    <name>A0AAD9DD93_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-isopropylmalate dehydratase</fullName>
            <ecNumber evidence="6">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Alpha-IPM isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">QTG54_006664</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1743067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DD93"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009316">
        <property type="term" value="C:3-isopropylmalate dehydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:L-leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01583">
        <property type="entry name" value="IPMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01577">
        <property type="entry name" value="IPMI_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.499.10:FF:000007">
        <property type="entry name" value="3-isopropylmalate dehydratase large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.19.10:FF:000003">
        <property type="entry name" value="3-isopropylmalate dehydratase small subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="entry name" value="Aconitase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="entry name" value="Aconitase, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01026">
        <property type="entry name" value="LeuC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01031">
        <property type="entry name" value="LeuD_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004430">
        <property type="entry name" value="3-IsopropMal_deHydase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004431">
        <property type="entry name" value="3-IsopropMal_deHydase_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050067">
        <property type="entry name" value="IPM_dehydratase_rel_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033941">
        <property type="entry name" value="IPMI_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033940">
        <property type="entry name" value="IPMI_Swivel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00170">
        <property type="entry name" value="leuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00171">
        <property type="entry name" value="leuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002458">
        <property type="entry name" value="PRK01641.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004016">
        <property type="entry name" value="PRK05478.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009116">
        <property type="entry name" value="PRK12466.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43822:SF9">
        <property type="entry name" value="3-ISOPROPYLMALATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43822">
        <property type="entry name" value="HOMOACONITASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="Aconitase iron-sulfur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="15" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0408">Iron</keyword>
    <keyword evidence="13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="14 21" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="18" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="18">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042240998" description="3-isopropylmalate dehydratase" evidence="18">
        <location>
            <begin position="20"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha" evidence="19">
        <location>
            <begin position="50"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase A/isopropylmalate dehydratase small subunit swivel" evidence="20">
        <location>
            <begin position="572"/>
            <end position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00031631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00033368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAK1743067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="804" mass="86442" checksum="96ED1EF1AF3B00D4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDL3</accession>
    <name>A0AAD9DDL3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Complex 1 LYR protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDL3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="1">
        <location>
            <begin position="11"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="159" mass="17663" checksum="66CA0ADD993F6D9F" modified="2024-05-29" version="1">MSNQSTIVINTYRSLAKLVRRLPEKQQTGALKQLRDGYRKHADETSSEKIADLIQEAGKKIAFLRIVTPKNMWTTTNTAAVGEAAATAAAQETKQSGVTRWVYRSSGEKDADGKPIMRKSSRVVSNFDGKNLDPCNINRHNSQLKRMGFANNLHAKGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDW7</accession>
    <name>A0AAD9DDW7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007034</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDW7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF831">
        <property type="entry name" value="NAD-DEPENDENT EPIMERASE_DEHYDRATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="334" mass="37744" checksum="5D47E637DEC6DF5E" modified="2024-05-29" version="1">MTMLRLVLPITQRSHHQPKKRRSTHQRLFLFILPIIAILTVLPNPTAAAMTAAPSSTIRTVMITGANGYLASHIVKQLLEKVTMSTHVYAMQQMNHPSGTYSNYHLHQHHLENCNILNRRVRWGAGYVNPGMEEPRMSSVDECMSAAAPQPEPPIKMNRIGQMILHNYLTRQEKLCQQWSEQSVQEGKLALNFRYCAICPTMIVGPPLLAADDDSYTPSGTMGSLYHVIKPTDVPSLIGQTIKETKRKSLNDSMSYIDVQDCAAQHVAAMENTMHQDELYPEISLDENYKYEGDDIIRPTQFNLDRMNSLGVKVKSIREIFAECISFFQSKGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEC7</accession>
    <name>A0AAD9DEC7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_007138</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEC7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1742573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="203" mass="22664" checksum="B57DA7CC9B5E7083" modified="2024-05-29" version="1">MLDIPGGELDEQKALQLKRSRYGLGDRRTLDELIEFSGVDLRHKRATIDGKNRCGNIQWVPFIEHPKGANFIPTFDDTTEEPLDLPYDKSSVWYDPQIDGAGAGMISRDVIENEEDPKEKELRHAEEKAAHAVFKEEAKQLAGNSHHADEHKRLAAALEEDGAERGHKEVVSSAAAAALKAEQMEKEGVVVFHPCYVGRLNQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEI4</accession>
    <name>A0AAD9DEI4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase S74 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEI4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030392">
        <property type="entry name" value="S74_ICA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13884">
        <property type="entry name" value="Peptidase_S74"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51688">
        <property type="entry name" value="ICA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S74" evidence="1">
        <location>
            <begin position="161"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="265" mass="29225" checksum="4E26EAF3E2340355" modified="2024-05-29" version="1">MRWDVQSKELRVPALGSFGSKLEVRSEVDFLSHTLRNVVLEPDTELQGLTFKDGIIENSILRNVTAVDLNLGDVVVETVSINDFTASNNVGAFVTVAEDGKLDASSTMKSNERQLLIDDDVIMSKSLQVEADLQVSGEAYLEGSLAVAGSVLGGGPYVDISDRRYKRNIQHLNSSGVLDDLLQLKGVSYELDTEQMTYTYLSGSKASAKTERQVGFIAQDVEVLFPELVYNDKDYDFLGLHYSRFVPLLVEGLKQLTQRCVSSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEM8</accession>
    <name>A0AAD9DEM8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">S-adenosylmethionine:tRNA ribosyltransferase-isomerase</fullName>
            <ecNumber evidence="5">2.4.99.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_006562</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.17" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEM8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051075">
        <property type="term" value="F:S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:tRNA queuosine(34) biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1780.10">
        <property type="entry name" value="QueA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003699">
        <property type="entry name" value="QueA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042118">
        <property type="entry name" value="QueA_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036100">
        <property type="entry name" value="QueA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30307">
        <property type="entry name" value="S-ADENOSYLMETHIONINE:TRNA RIBOSYLTRANSFERASE-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30307:SF0">
        <property type="entry name" value="S-ADENOSYLMETHIONINE:TRNA RIBOSYLTRANSFERASE-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02547">
        <property type="entry name" value="Queuosine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111337">
        <property type="entry name" value="QueA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1742965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="152" mass="16862" checksum="D312E85D0BFCC258" modified="2024-05-29" version="1" fragment="single">MHAEHFYVNVGELRSIVKAMEAGKPIAVVGTTSTRTLESLYWLGVKRLRGISVNDDTKQLELGQFEWRGLSVADPSITAVTSFKALIDGMSDDEILIGQTSLMITPNSYNFKVIDHLVTNFHAPDSTLMLLVSAFLGKQNDVTTIYEEAQNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFQ9</accession>
    <name>A0AAD9DFQ9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">4-hydroxyphenylpyruvate dioxygenase</fullName>
            <ecNumber evidence="4">1.13.11.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_004713</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 3/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the 4HPPD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.27" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFQ9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003868">
        <property type="term" value="F:4-hydroxyphenylpyruvate dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006572">
        <property type="term" value="P:L-tyrosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08342">
        <property type="entry name" value="HPPD_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005956">
        <property type="entry name" value="4OHPhenylPyrv_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041736">
        <property type="entry name" value="4OHPhenylPyrv_dOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11959">
        <property type="entry name" value="4-HYDROXYPHENYLPYRUVATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11959:SF1">
        <property type="entry name" value="4-HYDROXYPHENYLPYRUVATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="domain" description="VOC" evidence="11">
        <location>
            <begin position="116"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="68"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1744180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="316" mass="34575" checksum="E2435166D18413BF" modified="2024-05-29" version="1">MATRRPCLPVSSTYNTLHSVTIMTGRTTAAIVVLTAAVQLLTSSSAFQLSSPSATRNNNLSIHQSSSQLYQTPTQHQQQEEGTTDSWKPTVSSLSERKQYFREQSAQSSEHLGTLGFHHVEFYAGDALMTAKRFELALGIPITCWSSLATGNDKCVTYGLECGVDNDSNVEPGDGVRFLITAPLSRAMQKQQEQTNKNGGAGSNVQMTAPNPLPGYDINHAHEFYAKHGLAVRAVGIEVEDANKAYAAAVENGAVGSMEPSAIPSYYDKEREKECRVAEVELYGDVVLRFVSFHGSTDKKSDDQNQVVREHHSFRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGV5</accession>
    <name>A0AAD9DGV5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PGR5-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003513</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGV5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016730">
        <property type="term" value="F:oxidoreductase activity, acting on iron-sulfur proteins as donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009773">
        <property type="term" value="P:photosynthetic electron transport in photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039987">
        <property type="entry name" value="PGRL1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31032">
        <property type="entry name" value="PGR5-LIKE PROTEIN 1B, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31032:SF1">
        <property type="entry name" value="PGR5-LIKE PROTEIN 1B, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="232" mass="26045" checksum="28C7024FDC0D0A87" modified="2024-05-29" version="1">MVRLTLEEKERIFLDALQSYHFNGRQLLNDAEFDLLKEDLSWNGSSMVNMNRKETQYLTAVQDYLKGKPSLSDSEFDTLKSELQEEGSQFASAKEPRCYIDSGICKVTYEPDNFRNNLLYLPVGAILSIVWLGIGFEIIEPLIRINPLILAALGAPLIYNGSVSITEQFIFPNNKIVYGPCPACENETRVYFGGILGVEGFDDVASVKCKKCKAVINVQKKSLRASTLPKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DH80</accession>
    <name>A0AAD9DH80_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_002416</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DH80"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050505">
        <property type="entry name" value="WDR55/POC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019:SF8">
        <property type="entry name" value="POC1 CENTRIOLAR PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="108"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="131"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1747072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="815" mass="90318" checksum="EC2A00F11E50D342" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHY7</accession>
    <name>A0AAD9DHY7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cyclin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHY7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00043">
        <property type="entry name" value="CYCLIN_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="1">
        <location>
            <begin position="50"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="245" mass="27632" checksum="5DB09D2713928FEE" modified="2024-05-29" version="1">MKMIPTENLSRNTDAVADSLAAMIKRELTTYSCYGYDGYLNLSASDPTMVTAGDRKQLVDWCYSIVDQCKLSRETVASAMEMADRFLDMPINSANAARVSDEALRDVCKFQLLIIAALYASIKINEKVTWGFLMDEMKYLTELAVRDYYFSTKRASTIALAAVFNVISDTSTKERKELLGAFLRLIVEYFDFDHPNQIAAATSRLKSLAKKSENLLQEDNLDEISLDDSVKTCKVLNRSCSQKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DI67</accession>
    <name>A0AAD9DI67_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Thioredoxin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_002358</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DI67"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042276046" evidence="2">
        <location>
            <begin position="31"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="28"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1747014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="164" mass="17675" checksum="FF7E885FBF354EF1" modified="2024-05-29" version="1">MIHQLILIAKMKLELTSLVALLAALSCVMAGSSPRPFGITKSCNTPSTTTILDIRGGAVHESSSLSDLESKIQSAALQNKLTIIDFTATWCGPCKAIAPLYKELSEEFDAQFIKVDVDENPDAAQKYGVSAMPTFLFIKGGEVVDRLMGANAARLKELIAEWSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIA1</accession>
    <name>A0AAD9DIA1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_000795</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIA1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009563">
        <property type="entry name" value="SSSCA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051888">
        <property type="entry name" value="UPF0148_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16537:SF1">
        <property type="entry name" value="PROTEIN ZNRD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16537">
        <property type="entry name" value="SJOEGREN SYNDROME/SCLERODERMA AUTOANTIGEN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06677">
        <property type="entry name" value="Auto_anti-p27"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1748856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="407" mass="44642" checksum="CE3B086C267A615C" modified="2024-05-29" version="1">MSWDKLLVSGRLLLSKRLHQGWNFSERNCLGSKCNGTPLMRDKNSTNEVCMVCGGSGNGCDGYYASEKQRDIKDHTEEEPNWEARLENGRSLLTQRLAQGWTMDASNCEGYQCNNMPLTKLGSDPSSCVVCGGSGSGCDGIYEQFRSAEVVDAERELVSQEISHLMSMGWVLKDSLCQQCFMPLVSEHEESDDLCILCGKVPNNTLMNAPVPDFRSDEVSKEAGKRLKMGWTLPNAPLCVYCGGLQMIPPNSTEMGCIMPGCAGDIEYVLEPNAFNQDGRMKHIGRGYDTSNVKKAVTEQCTDQAEVVSPCVNMQQSLDDEPSSFPFNYVGVPHKDEDPSVLSDDTSQTSVASSALGRILEKLDDAKYQLKVLSERSNADPIECTAKQIEIASLIEKLARAVGDGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIH4</accession>
    <name>A0AAD9DIH4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Guanylate kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001322</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIH4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042098200" description="Guanylate kinase-like domain-containing protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="585" mass="62996" checksum="DF73393B6D63AE1B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIQ3</accession>
    <name>A0AAD9DIQ3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">WLM domain-containing metallopeptidase</fullName>
            <ecNumber evidence="8">3.4.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_001592</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIQ3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013536">
        <property type="entry name" value="WLM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053000">
        <property type="entry name" value="WSS1-like_metalloprotease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46622">
        <property type="entry name" value="DNA-DEPENDENT METALLOPROTEASE WSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46622:SF1">
        <property type="entry name" value="DNA-DEPENDENT METALLOPROTEASE WSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08325">
        <property type="entry name" value="WLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51397">
        <property type="entry name" value="WLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="WLM" evidence="7">
        <location>
            <begin position="29"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="6">
        <location>
            <begin position="393"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="198"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="295"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="351"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="17"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="198"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="208"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="244"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="351"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1747629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="462" mass="50881" checksum="57D3C66C8F5D3841" modified="2024-05-29" version="1">MVGGANNNGKKRPFGSTIRTFNDISNDAENDPANSNSKIVVQHIPNLPNDNEAAAILRRIHYEFKEIIERRKWNLLSITEMCCCGDGKDHTPHKRGGRKTKIMPNNVLGYNLTASSYTKTHEIHLRLRHPRTHALLDYESIAGTMCHELAHCVRGPHDAHFYKAMNEIEEQYAIYLAKGVVVDKNGFPLGSNDAHVLGGSGPGGGGTASSSKTAAAKAAESRRKKSANGLTNGYVLGGKRRAKPKDPREAALQAAERRLMDSKFCLPCNEVIEILADSSDEEVNDDDDSDVQLIEPTTSAAKSSKPKSKSKNGYQALDTKPKAVDYTTTTTTASSDDSVIDLTEDSFDMKNSTSFDDYLTSPTSAQKKPSLSRPKQNQATISMSDGEDDANEYDGEKDWTCPRCTLQNTSIVLVCEACNLERQPSKQQQKKLRDEEISHIKQNEVKQSMETFGGFNIYGSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIY0</accession>
    <name>A0AAD9DIY0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA replication checkpoint mediator MRC1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001817</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIY0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="642"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="476"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="523"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="551"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="583"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="648"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="666"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="679"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="692"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="785"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="804"/>
            <end position="821"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="926" mass="103185" checksum="6A0116DD94A36933" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJ00</accession>
    <name>A0AAD9DJ00_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA dimethylallyltransferase</fullName>
            <ecNumber evidence="3">2.5.1.75</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_001877</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>adenosine(37) in tRNA + dimethylallyl diphosphate = N(6)-dimethylallyladenosine(37) in tRNA + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:26482"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10375"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74415"/>
            <dbReference type="EC" id="2.5.1.75"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IPP transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.75" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJ00"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052381">
        <property type="term" value="F:tRNA dimethylallyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00185">
        <property type="entry name" value="IPP_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039657">
        <property type="entry name" value="Dimethylallyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018022">
        <property type="entry name" value="IPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11088">
        <property type="entry name" value="TRNA DIMETHYLALLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11088:SF60">
        <property type="entry name" value="TRNA DIMETHYLALLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01715">
        <property type="entry name" value="IPPT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="4 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042110983" description="tRNA dimethylallyltransferase" evidence="11">
        <location>
            <begin position="24"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="60"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="66"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1747914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="605" mass="67441" checksum="2D1BE31F3EB636DE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJ54</accession>
    <name>A0AAD9DJ54_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">60S ribosomal export protein NMD3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_001593</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the NMD3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJ54"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039768">
        <property type="entry name" value="Nmd3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007064">
        <property type="entry name" value="Nmd3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048899">
        <property type="entry name" value="NMD_SH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048898">
        <property type="entry name" value="OB_NMD3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12746:SF2">
        <property type="entry name" value="60S RIBOSOMAL EXPORT PROTEIN NMD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12746">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04981">
        <property type="entry name" value="NMD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21193">
        <property type="entry name" value="NMD_SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21192">
        <property type="entry name" value="OB_NMD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nmd3 N-terminal" evidence="9">
        <location>
            <begin position="29"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="60S ribosomal export protein NMD3 SH3" evidence="11">
        <location>
            <begin position="267"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="60S ribosomal export protein NMD3 OB-fold" evidence="10">
        <location>
            <begin position="357"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="504"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="510"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF21193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1747630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="602" mass="67485" checksum="29C2093F86394012" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJE3</accession>
    <name>A0AAD9DJE3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mediator of RNA polymerase II transcription subunit 6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Mediator complex subunit 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MED6</name>
        <name evidence="8" type="ORF">QTG54_001863</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the Mediator complex subunit 6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJE3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.580">
        <property type="entry name" value="Mediator complex, subunit Med6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007018">
        <property type="entry name" value="Mediator_Med6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038566">
        <property type="entry name" value="Mediator_Med6_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13104">
        <property type="entry name" value="MED-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04934">
        <property type="entry name" value="Med6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0010">Activator</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="205"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1747900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="249" mass="28055" checksum="A96BB4815771D62E" modified="2024-05-29" version="1">MSESASFVDPAFLARFGLTRINAIDYFLHPLNPFRTKAKTSNEVLGMQGINIGTLMQWGTGARPGPLPLDQGEDEYRVALSRLTGEQYELLPMSTNIEGMTPQQMSALFTIRHVHRTSHNHTTVLGIYYILEGVIYKSPTVRGLMKANIARTLAGLSEACDALSVCARYDPSSGYSWKFDPDEDDDEDNKFYSSIQEKRKRRRRQILDNRRPGERTAEEEEGIRASEAIDRILSRLSKSDVVVKGKPII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DK39</accession>
    <name>A0AAD9DK39_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Plastid lipid-associated protein/fibrillin conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_000257</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DK39"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041989467" description="Plastid lipid-associated protein/fibrillin conserved domain-containing protein" evidence="3">
        <location>
            <begin position="18"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="60"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1748318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="153" mass="16714" checksum="16417D91CB365E58" modified="2024-05-29" version="1">MMLRLALLSLLAAGSTAFMVSPNTVRTHRPVTAQNLIMTEEEITTILGKAHGCVDSECAVDDVDDLIAELKDQQKVLSERLENIMNVVSHLQHANTKEARKTDDVRAIVKDMLRVFTTSDGKFAMGFSGDIGDGPTTAYDALPPKPWKADMSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DKN4</accession>
    <name>A0AAD9DKN4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamideisomerase</fullName>
            <ecNumber evidence="3">5.3.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_000842</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 4/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the HisA/HisF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.16" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DKN4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003949">
        <property type="term" value="F:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04723">
        <property type="entry name" value="HisA_HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000110">
        <property type="entry name" value="1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011858">
        <property type="entry name" value="His6/HISN3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044524">
        <property type="entry name" value="Isoase_HisA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02129">
        <property type="entry name" value="hisA_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43090">
        <property type="entry name" value="1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO)METHYLIDENEAMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43090:SF2">
        <property type="entry name" value="1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO)METHYLIDENEAMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1748903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="266" mass="28789" checksum="F79C846ADCD12500" modified="2024-05-29" version="1">MKFRPCIDLHSGQVKQIVGSTLSDDKQNALTATQSSVEAENFSTDKPASDFAVMYKDDGLTGGHVIMLGPGNQDAAKSALEAYPQGLQIGGGITSSNASEWLSYGASHVIVTSFVFHNGQIDFDRLNGLVDQIGKDRLVLDLSCRRKVGDTTGPYFVVTDRWQTYTDVEVNEETLKMLGGYCAEFLVHGVENEGKRCGILEDLVQLLGKYSPVPVTYAGGVQGLDDLDRVKTLGNGNVDLTIGSALDCFGGDIKYDDVVAWHKKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1LVD6</accession>
    <name>A0A8K1LVD6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Photosystem I assembly protein Ycf4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10 12" type="primary">ycf4</name>
        <name evidence="11" type="ORF">QTG54_017188</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="12"/>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2021" name="Front. Plant Sci." volume="0" first="0" last="0">
            <title>Chloroplast Genomes for Five Skeletonema Species: Comparative and Phylogenetic Analysis.</title>
            <authorList>
                <person name="Liu S."/>
                <person name="Xu Q."/>
                <person name="Liu K."/>
                <person name="Zhao Y."/>
                <person name="Chen N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CNS00100</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Seems to be required for the assembly of the photosystem I complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Plastid thylakoid membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Plastid</location>
            <location evidence="10">Chloroplast thylakoid membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the Ycf4 family.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MW679506">
        <property type="protein sequence ID" value="UAM91391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_010200901.1">
        <property type="nucleotide sequence ID" value="NC_058701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1LVD6"/>
    <dbReference type="GeneID" id="68638028"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00437">
        <property type="entry name" value="Ycf4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003359">
        <property type="entry name" value="PSI_Ycf4_assembly"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002712">
        <property type="entry name" value="PRK02542.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33288">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33288:SF4">
        <property type="entry name" value="PHOTOSYSTEM I ASSEMBLY PROTEIN YCF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02392">
        <property type="entry name" value="Ycf4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="12" id="KW-0934">Plastid</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00046286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1732145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UAM91391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="181" mass="20597" checksum="BC47EA789EFFE729" modified="2022-08-03" version="1">MQDQIRQEKILGSRRFSNYFWATLLLIGGLMFLLAGISSYLKINLLPFANTTELVFIPQGIVMMFYGTLSFGLSIYIIATLFWDIGSGYNEYNKVENLVKVVRKGFPGKNREILLTYPLNNIQSIGIKISEGLNPQRIIYLCLKDERKIPLTPVQQPDSISDLEDQAADLAKFLDLKLENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRJ8</accession>
    <name>A0AAD8XRJ8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_017008</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000074">
        <property type="protein sequence ID" value="KAK1732308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRJ8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="74"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="306" mass="34385" checksum="DF02A1B98B737462" modified="2024-05-29" version="1">MVKEQQHQRRRAPVIRGRKRSGRARTAARSSTRAAAATVQRRTRGTHLAASSRSAAAAASNHSSAATTAQQVQLRNIRAEKRRLLQQLAESERRAKVAEEDRDKLLMLLPEEDKPADEVIDELNESDPVLRDRGTELWQNVWCQDDVSIALTFPTSKSVVCESVDEVGGNDMPGVYSSGVISNGRTTQSIWMKGKGYTLVGLVTCDEEKAALRHRAGEDFRQMPMMTNVYSAHWDAREGDVFTIEVDMIERRAELFISDKDASHQLTPHITWEGLPEKVWVAVAFKRNSEREAVLMPCIHHNVTEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSK6</accession>
    <name>A0AAD8XSK6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ribosome-associated GTPase, OBG family</fullName>
            <ecNumber evidence="9">3.6.5.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_016278</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000055">
        <property type="protein sequence ID" value="KAK1732947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSK6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.350">
        <property type="entry name" value="GTP-binding protein OBG, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.210.12">
        <property type="entry name" value="GTP1/OBG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036346">
        <property type="entry name" value="GTP-bd_prot_GTP1/OBG_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006169">
        <property type="entry name" value="GTP1_OBG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036726">
        <property type="entry name" value="GTP1_OBG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045086">
        <property type="entry name" value="OBG_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015349">
        <property type="entry name" value="OCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03595">
        <property type="entry name" value="Obg_CgtA_exten"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702">
        <property type="entry name" value="DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702:SF44">
        <property type="entry name" value="GTP-BINDING PROTEIN OBGC, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09269">
        <property type="entry name" value="DUF1967"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01018">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102741">
        <property type="entry name" value="Obg GTP-binding protein C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82051">
        <property type="entry name" value="Obg GTP-binding protein N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51883">
        <property type="entry name" value="OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51881">
        <property type="entry name" value="OCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042173387" evidence="5">
        <location>
            <begin position="26"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="domain" description="Obg" evidence="8">
        <location>
            <begin position="123"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="OBG-type G" evidence="6">
        <location>
            <begin position="261"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="OCT" evidence="7">
        <location>
            <begin position="434"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="545"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="548"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1732947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="605" mass="67010" checksum="63152D21BD93A419" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XT88</accession>
    <name>A0AAD8XT88_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000049">
        <property type="protein sequence ID" value="KAK1733416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XT88"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="250"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="311" mass="33247" checksum="54C3B6FD08AA8B50" modified="2024-05-29" version="1">MSGSKSSSSSSSRARAANTNSNKLLSLSRVATLVFAALTLTSYTTTAQTPPPSLCSCSPTKFNFKLNFQGTCESTSLTGVNDELCFINVRPGMESVAENVDFEIENILSMMSANQRALNSVIPTVVTSVDIFEYDTTNELTVINQEIFSNQSLSDGDIIEFTSISSKLDPNKPLQEQLEYFPGGLILRYTGVNSNNEDVINTFAWGYNIEDCTTEQISAGDFIGWTIVDDVTAANGAFCPAIVTPPPTLSPTTLAPTTTTAKPVNPTSSPTSTTTKMSITTKSSKHSARSKAAKVPSASKATKASYSLIYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUB3</accession>
    <name>A0AAD8XUB3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_015685</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000046">
        <property type="protein sequence ID" value="KAK1733642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUB3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="12"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="77"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1733642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="253" mass="28647" checksum="A1D8D8056B3CBE66" modified="2024-05-29" version="1">MSDGNAVDKLCCASCGIEEVDDIKLKECADCDLVRYCSNGCQREHKLQHEEAYKKRATELRDELLFKQPESSHRGDCPICMIPLQLDLSKSSMAMCCSKTICNGCNYANQKREFEGKLQHTCPFCRKALTFSNEEHDKQRMKRIEANDPAAMYQEGFKQDGKGDYSSAFEYYTKAAQLGDAEAHYQLSILYHHGHGIEKDCGRQIRHLEEAAIGGHPGARYNLGCIEWNDNKERAVKYFIIAATQGLINQSNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUD3</accession>
    <name>A0AAD8XUD3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015337</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1734079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUD3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="108" mass="11923" checksum="ACBFF9BE8BF58D3F" modified="2024-05-29" version="1">MPFKSSATTVTSSDRQKSSKSIAQDAQKSVATSPKKLRRNNSMKLDLPIRMQKMKSAGFIVGPVKKRYESLKCDSGISGSALEKTSSSETQESKKSQDEMDIHRGFYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV51</accession>
    <name>A0AAD8XV51_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015025</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000040">
        <property type="protein sequence ID" value="KAK1734258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV51"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="2">
        <location>
            <begin position="43"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1125" mass="126099" checksum="3980330840FB9E24" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVP7</accession>
    <name>A0AAD8XVP7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidyl-prolyl cis-trans isomerase, cyclophilin type</fullName>
            <ecNumber evidence="6">5.2.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_014609</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVP7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF6">
        <property type="entry name" value="SPLICEOSOME-ASSOCIATED PROTEIN CWC27 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="302"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="5">
        <location>
            <begin position="76"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="18"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1734736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="336" mass="37055" checksum="F6C380F87B2E6539" modified="2024-05-29" version="1">MADEIDDPGVDFHGGMGDDPDQLDGEEVMEDDPEVKEIMGDEVDDAADEQRTNIRGSGNAPKSVGSDQEEAIVQCDTSAGPITMHFYRSWSPHGYDRATTLFEKGYFDHSHFFRVVEHFLVQFGIGYTTDKELKAFSLSTIPDDPKRPELLPFKEGMMSFAGSGPNSRSSQMFIAYDRAGGLGQSPWETPFGKVTSGLENVKNFYKGYGDMPPWGKGPQQGPIHNRGASYIESDFPLLDKFETCSVQRMNQSGAGVIKDVIVIKQSGAEVIKDANVVKNVAAEIKKANVVNKAETKEEVPSFPFTTLLILSSIVLSVLLGLGYMRNKKKKKYNKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW15</accession>
    <name>A0AAD8XW15_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XW15"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="410"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="455" mass="51560" checksum="6104CBCE28324AA0" modified="2024-05-29" version="1">MMYLSDLPTGALAHVSSFLAAPSRALFAVALNSRESSSAIAGDDWEYLDFGHIEKDLAAKLIDDDIRDIIVAYQLCQYYLEKDLDLAAKISDDDIRGVLLSIDAVNNLKKLRLTNCINISGAGLEPLRGSTIIQQIDLSLVGDHESPRLDPEPPISCAEVIPILDSIIERGEECSLEYLQFPNEWRKERNTESDFHAFLTRYNELLCSRAVVCLKCNHDMFEVYSMPTMMEMSDSRYGTQNFTCYNCMDHYCEYCADDGGVYYIGGSCKKCERIYCLHCKKVDVCGPCGSWYCADCIDFKQCPKCDGNTCPDCFSECSRCHENTCSDCVSGASCHNTCCADKISCNHCAENGDAFRWCDRCSVDYCVDCCDSDIYAVKFCDVCEDTLCGQCRVKKCMEWRNCARCYHFSFPALLEDKERTQTKNNEMENENKEQRNEINELKRKVKDLTGELEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWA2</accession>
    <name>A0AAD8XWA2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GRAM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_014716</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWA2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031968">
        <property type="entry name" value="VASt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47666">
        <property type="entry name" value="PROTEIN VASCULAR ASSOCIATED DEATH 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47666:SF1">
        <property type="entry name" value="PROTEIN VASCULAR ASSOCIATED DEATH 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16016">
        <property type="entry name" value="VASt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51778">
        <property type="entry name" value="VAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="VASt" evidence="6">
        <location>
            <begin position="220"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="160"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="23"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1734843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="477" mass="54142" checksum="659DF3D63F720A94" modified="2024-05-29" version="1">MSFNSPIRQRTASENEVRDRLVRSTNSSGAATPPRSSSKQMYTTEFIKALFGDTGVVVGDYSCSYQRQAGRLYVSTDAVFFYSNLFGFEKRIKIDYTNAVEIDLVRTTSVFIKTSDEEFIFRSFKGEDRQSVLELIKTFHSKTSSSLDIPSAIHSVDTQSDDLASLSEHDDNETKQQLPTSQDSPEDTAINTSKAGSIVPNSLEGTLLWEQMKKHSKDWDSIITAQKLQFNSVSDFFDTFLRDSSPRSMSYFQSKVMGDSNVSLEAWAKNTAPEGESSAAADSLSRVFEFEKTTRWAVAKVKRRQTYQTCGKNAIIQNFTHLLGIPQADAFFVEDMWLLETEATHVTLNVKCRIVWLKNTMLKSVITNRTKTEAKEWFDKYIPYVSQKSDETPIPVQREEVAAETNQVISVLFSIAKFARFIFRLCRESPVFALLILLAIYTCHLKQRIVLLEKLVDEVQMNMIQQLDRLSAGQIDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWP8</accession>
    <name>A0AAD8XWP8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">3-phosphoinositide-dependent protein kinase</fullName>
            <ecNumber evidence="7">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_013905</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWP8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF37">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT PRKX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="15"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1735291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="410" mass="45816" checksum="F6E345DFD595F83A" modified="2024-05-29" version="1">MTTTADPRDYSPSDFLYGPIIGEGRFGSVVYAEHATQEVHDGGVGNKLPRPQDKQNDGQGYAVKMIPKSEILRYNLLQAVMTEKRILAEVLSSNQDSDTSSSSGSAALMIPKLFCCFHDDSYLYFVLELCSGGTMLDLVDHCTKIRRDNSCNDSISDTPLMDIAWVRYYAGQLVRVLEYIHQKGVIHRDISPRNILFTSRGALKLCDFGSAVVIGTSSKGASRRIDNDDFVGTADYVCPEMIRGSIKSGCTGTTSSMPQQKELLGAIDLWSLGCLIFQMSVGESPFHAESDQGAFQRVLDYTNHKSRIHVPPYTDMDAKDLILSLVAIDATSRIGLSDGVVSSKESKKPYHSLRRHKFFTTEDKLQQQFWTLLENNSVNPPYTPAEQSWMTQLHQSGRKMKRIEEMCYEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXB9</accession>
    <name>A0AAD8XXB9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">CDK-activating kinase assembly factor MAT1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_014211</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXB9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015877">
        <property type="entry name" value="MAT1_centre"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12683">
        <property type="entry name" value="CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12683:SF13">
        <property type="entry name" value="CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06391">
        <property type="entry name" value="MAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="14"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="231"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="165"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="233"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="245"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1735145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="348" mass="39486" checksum="1FAE99781A0645C3" modified="2024-05-29" version="1">MGDDYDDDQNLFSCAICGLSEGDASNLTTQNNLQTNGTLGCGHQFCNSCVERELSRRKTFPCPICKTVVKRVTLSTRTLDDLQCEKDTSWRRRILKIYNKVEKDFPTLLEYNNYLEEVEDIIFSIVNEEPNAEEVKAKVKAYEEKNKSQIVIRQSQRADEERCIADRIASETREAERRKREFEEVEKAVASTKRKFKQETTEVMLGERDQVSAEVAAAQMQGYRNELIRQQRGRGGQAPGGGLPRVREPEGGLGKDKVKDRDMYRKRQAAGGGITSENIAVHERDWHLTVASMFPRRSKQYERRGSSATLHHGSVAASRTYIETDKVSEGNKLVACGLKPKRGRKKQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXN4</accession>
    <name>A0AAD8XXN4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013939</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXN4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042281846" evidence="1">
        <location>
            <begin position="27"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="272" mass="29766" checksum="8BE74EEF578C7AC3" modified="2024-05-29" version="1">MASTLSSHSLLWAIFALLSISPNVASQGLQPYDCIDPQNPGLTSRVEIGQNTTVCLYTGPDGDWNSNIQYKRFSVNLVADEFANYKVPGSYSAIVGGNFFNGNATQIFAASQSALSFQRRYYDATTNFIFPYLTIIVDVVDGVVRGIAWDDACVFCEKKQCLPNTYNFDGTEATSEQASQPTNGCYLTKAICEGFQATGSDACDLKLYVVWTGTDVNGNVLKSSDSRFSAFPPNRIQEQVVGSYDSMMSEVQNFGQDVKDKLNSVGNFFKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXQ2</accession>
    <name>A0AAD8XXQ2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zf-MYND and TPR domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_014069</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXQ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="7">
        <location>
            <begin position="17"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="272"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1735455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="298" mass="33290" checksum="33E2514C4161B6FE" modified="2024-05-29" version="1">MSADDCEAGVMMMMSCCASCGIAERDEIKLRECATCDLVRYCGDKCQENHTAQHERACMKRAVELRDEILFKQPESSYLADCPICCLPMPLDLSKSIVAVCCSKSICRGCDVETQKREFEPVGNELWRKQRMKRIEANDPVAMCREGAEQYKKGDYSSAFGYYVKAAELGDVDAHYRLSLMYYLGKGVEKDGGKEIYHLEEAAIGGHPTARCGLGCHEWRNGNTERAVKHLIIAASMGHDGSIKFLMDEFRRGFVSKDDLAAALRAHQAAVDATKSPQREEAEACDRIRDTMHAKDSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXT9</accession>
    <name>A0AAD8XXT9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-terminal acetyltransferase B complex auxiliary subunit NAA25</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013767</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MDM20/NAA25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXT9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031416">
        <property type="term" value="C:NatB complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019183">
        <property type="entry name" value="NAA25_NatB_aux_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767:SF3">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 25, NATB AUXILIARY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767">
        <property type="entry name" value="N-TERMINAL ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09797">
        <property type="entry name" value="NatB_MDM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="795" mass="87840" checksum="3AB350636E75783D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYF8</accession>
    <name>A0AAD8XYF8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013345</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYF8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05121">
        <property type="entry name" value="ABC1_ADCK3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050154">
        <property type="entry name" value="UbiB_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566">
        <property type="entry name" value="CHAPERONE-ACTIVITY OF BC1 COMPLEX CABC1 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566:SF113">
        <property type="entry name" value="PROTEIN ACTIVITY OF BC1 COMPLEX KINASE 7, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="2">
        <location>
            <begin position="318"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="771" mass="85527" checksum="CCA46F2BF049839A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYT4</accession>
    <name>A0AAD8XYT4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_013487</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYT4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1735781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="186" mass="21301" checksum="D039451EEAB6EEDE" modified="2024-05-29" version="1">MTDLIIVDFPRQRKLPKVQFAETAQLHTYKRHNVPCRELYFTTREYDLMKLAVREDVLKARAGRTSNDTADADADALTKAEDRSSFWIGIAHLLTPACIDEVRTCRAQCIYAVLTEQARQGLSTRFNSWETIALASFAQTRQPVLRARELAIPEERHKRTTGRLNIGGDGWTEFVWDEGGRSMKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZF2</accession>
    <name>A0AAD8XZF2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6824 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012783</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZF2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049227">
        <property type="entry name" value="DUF6824"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20710">
        <property type="entry name" value="DUF6824"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6824" evidence="2">
        <location>
            <begin position="83"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="419" mass="45615" checksum="661F00123539FF44" modified="2024-05-29" version="1">MSSNNLSIMAAAAAAAASSSLSPSCLLAASSTSSSLLPGSTSTSSPKLLVLPPKLTASISPLQWNGTDYLVDGITRKDIHAHDVLSGRGGASNNHPGNEAFRQLVNKVKFDYLQCPKREKPLLAMRIVQAVRAQSPPGRFLQHDKLTDTWKDVGDTKAREKTSQALREGAPIIRDLAHKPSPSNLPNVLKQVKKEERKNEPTRKSDYVVSLPSTHSSGIPPSGLSPLSVETATKPDPSCLTFPNHPQMEEHRHPASTLSIEATRPSFYPQHSVESRRIVSGDFSAAARNELPPVPFEIVRGLLLGHIDPVTVATSILSREEAAIVAYRHHLNARPARMFPTAAQTEIIHGKKHLLEGPASGEPMVRDQTTSIESLELARIPSTSSTDHSEPKERTIKSPKQQTIQRRAPFKKRRLIVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZJ2</accession>
    <name>A0AAD8XZJ2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">D-2-hydroxyacid dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_012269</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZJ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05300">
        <property type="entry name" value="2-Hacid_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43333">
        <property type="entry name" value="2-HACID_DH_C DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43333:SF1">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE NAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="3">
        <location>
            <begin position="143"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1736824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="373" mass="40389" checksum="53EA3E9085C7EB92" modified="2024-05-29" version="1">MRCQPTITSRPTVTVFSSIQGIAESLRHADPNLPLQVVQDEALCGYGGTVEFNPSALSTETKTILQQAEILISEPAVVAALLDHDSSALSSLKWCQSTYAGVDPLFNSSFLSSSSSSSSTIIPWKLTRFAGCFGPPIAEWCIARIIEHERSFVATAKDQLQKSWAGSRDAVTNYRYLSSMTLTILGCGDIGRCIARAAKAFGMKTVGYVRTIPSSSNNDNRNVAEETGVDEYTTDLTSALQSGDYIVSVLPSTPTTRGLLSKGALKAASTEKGGLCPVFINVGRGDVIDEKCLLEALDKKFISGAILDVFVEEPLPTNSGFWSRPDVIVSPHVSGLTQASDVPKVFLSNYQRYVENDRSTSELKFLVDWKKGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1L8</accession>
    <name>A0AAD8Y1L8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutathione-independent glyoxalase HSP31-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_012032</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase C56 family. HSP31-like subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1L8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019172">
        <property type="term" value="F:glyoxalase III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019243">
        <property type="term" value="P:methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03141">
        <property type="entry name" value="GATase1_Hsp31_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050325">
        <property type="entry name" value="Prot/Nucl_acid_deglycase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094:SF11">
        <property type="entry name" value="GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094">
        <property type="entry name" value="PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="DJ-1/PfpI" evidence="4">
        <location>
            <begin position="25"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1737165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="224" mass="23577" checksum="D02F89B71098EDF0" modified="2024-05-29" version="1">MTKVVLVSTSATSLQGHDTGLWIEELAAPYYEFKKAGYEVVIASPAGGPIPIDKNSMGEGFFTDAAKKFMHDGEAVGELCHSTKLDSIDFASVDAIFCCGGHGTCVDFHDNATLKSAIESMFAGDKVVSAVCHGPMALPQCNKPDGTPLIAGKVVAGFKDSEEVAVALQDKVPFMLESKMKELGAKYESADDWNSKCCVDGKLVTGQNPQSSEACAAAVISILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1P8</accession>
    <name>A0AAD8Y1P8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Leucine-rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011564</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1P8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="227" mass="25735" checksum="96CE3D807A0C80BD" modified="2024-05-29" version="1">MPGVEVVERFAFINCKALTDVECGKLEIIRELAFSGCESLRSIDLPSARIVEGKAFNYCEALTDVKFDSKLDRIEEEAFCYCTALERITIPLKDDMITADDIFIRCDNLKHVDLVEGAIHKIIAALQLEEWRNDVNEEIDSINQILPIASAGRWVYDVGDKARAIRTWIRSVLGKIIHYQAEHQRLLDEDIATSLQLALSQDIVMNNVLPFLELPSYTFEVGGDQEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1Q2</accession>
    <name>A0AAD8Y1Q2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">LNR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011708</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1Q2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042127959" description="LNR domain-containing protein" evidence="2">
        <location>
            <begin position="16"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="252"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="339" mass="37801" checksum="570B04EDC90A8457" modified="2024-05-29" version="1">MNLKILIFCINAVAATSHNHHLRQKHEQHDIVFRATKSQLRRLHKGDEEAQDLEALRVLRGSRTLGNVNCDDVDDQGLTVNWTCDRDTEECGNHPNDCKTKCDKEKDCHGHGECHHRKCECDEGYEEDDDCGMQDVVYTFNVVLQGDEARTAECIAALDRLATLSLDNLSLPSTVSVNSKSRRSLQRRLTKSSNKSEKGALEIEINIVPTHDCSEAELAVQALENLDADAKLLDGDEVDSDDDLPAPYVCLVQESEDILKDAKKEKDAEDLEEDLDGLINTCNVTGIVDGDDVAICASDCHDDIEDDCEDELDPDEEDENDCGGLHNDLKHCYKKCYGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1Q6</accession>
    <name>A0AAD8Y1Q6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_011726</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the ABC transporter superfamily. ABCF family. EF3 (TC 3.A.1.121) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1Q6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000309">
        <property type="entry name" value="ABC transporter ATP-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000011">
        <property type="entry name" value="Putative ABC transporter ATP-binding component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051309">
        <property type="entry name" value="ABCF_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42855">
        <property type="entry name" value="ABC TRANSPORTER ATP-BINDING SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42855:SF1">
        <property type="entry name" value="ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041980345" evidence="7">
        <location>
            <begin position="22"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="336"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="669"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="49"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="151"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="436"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="151"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00061344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1737440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="939" mass="103389" checksum="366D784FC1D4335F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1U4</accession>
    <name>A0AAD8Y1U4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">GPI mannosyltransferase 2</fullName>
            <ecNumber evidence="11">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_011930</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the PIGV family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="11"/>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1U4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031501">
        <property type="term" value="C:mannosyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000009">
        <property type="term" value="F:alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004376">
        <property type="term" value="F:GPI mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007315">
        <property type="entry name" value="PIG-V/Gpi18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12468">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12468:SF2">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04188">
        <property type="entry name" value="Mannosyl_trans2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 11 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4 11" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="16"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="321"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="378"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="460"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="541"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="564"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="604"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1737644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="627" mass="70380" checksum="88E7A473410AC0B2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1Y1</accession>
    <name>A0AAD8Y1Y1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Jacalin-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011408</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1Y1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.100.10.30">
        <property type="entry name" value="Jacalin-like lectin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001229">
        <property type="entry name" value="Jacalin-like_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036404">
        <property type="entry name" value="Jacalin-like_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01419">
        <property type="entry name" value="Jacalin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51101">
        <property type="entry name" value="Mannose-binding lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Jacalin-type lectin" evidence="1">
        <location>
            <begin position="71"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="264" mass="29384" checksum="67C3CDA0A845BC14" modified="2024-05-29" version="1">MTTNTNTNSKMFLRFDRKEHVFAAPTDATVPEATDLRALIIAAEGETQGHRPPRGFNDLQKSLTLCVEGKVDIRRITVFHSRRCCMGVKVVYSCNGNLHIADTHVSNYGYYEGVARESVLNFADDEYLCEVRTRQGDITDQITICTNKRTVSFGGTGGGPDPRDVSNTPVDLTKRVVALVGSFHGVLSRIGTVSILRNWEIIRDFVLVRELVESNRASPKPLNAKRVTFQNVEKEVAVLQELMKVDTGIFRHVLSFLIANVASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2F4</accession>
    <name>A0AAD8Y2F4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011897</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2F4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="191" mass="22054" checksum="196567C339CDA035" modified="2024-05-29" version="1">MMNRQLLRTLRLTRRQWNCSSAANNAIGIHHHYNATRLASPLITNNVIPTTHHMKLISSASFSTDADSKSSAEKVGIVSRIRTFIKTIFGSNDDTPRGVQERKDMYWILLAVTHRKLRMEAQQTQLSSGNNKDQLTWNNESKEEIKQYMEEAVSYLDEQTDISEMPLRRLRQEIQSRLEPQIIQLLSEENG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2I8</accession>
    <name>A0AAD8Y2I8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2I8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="129" mass="14533" checksum="9B2748EEACD628EB" modified="2024-05-29" version="1">MNKAAELGLEMAHHSLGIAYAYGDEGEKNEKKALYHFRLAAIGGLLEARHILGQSWLQRDPNMAYKHFLIAAEAGYDESLKEVKTGYAEGHVKKDVFEKALRAHKAAKDEVKSEPRDKAAEWYRRHGPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4E9</accession>
    <name>A0AAD8Y4E9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CP12 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4E9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039314">
        <property type="entry name" value="CP12-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33921">
        <property type="entry name" value="CALVIN CYCLE PROTEIN CP12-2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33921:SF15">
        <property type="entry name" value="CALVIN CYCLE PROTEIN CP12-2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02672">
        <property type="entry name" value="CP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042010635" description="CP12 domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="168" mass="18422" checksum="A093FB6A66294AF5" modified="2024-05-29" version="1">MISSTLRATLLCFLATNTPAAAFTNHRITNTASHTNKTNNHSSYRSSELNLYNSVEEAIGEAQRVCNEQGGDSEACKVAWDIVEELEAADAHRTPATPTSQQELSYGPLIMSLDLLSAKIDRKMDELNKLSTSLVESGAGPEVQRLAYASEEMKGILEEAVRSLDQYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4U7</accession>
    <name>A0AAD8Y4U7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Hexosyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4U7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050587">
        <property type="entry name" value="GNT1/Glycosyltrans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11183">
        <property type="entry name" value="GLYCOGENIN SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="376" mass="42949" checksum="C9ED2786AA5EFFFB" modified="2024-05-29" version="1">MNTVSSMSMNILFLRRSDASNSISTTRELGNWGLKLKTVIFASILILTSLSLLYNVHFQNTLLEQYKYSRSTPTHPSHGAAPRRFAIVNFVESMDQIYGVYSIQKQMMKHNISAAHVVLVPHVMKQSLQDVIALWVGEENRRFVVKDDIVGKVSSKSGIWKGVFNKLWAFNLTEFEKVIVLDGDILIRTDITHWFDYPTPCAIQAGNDLNWNSGAMVITPDSMEFQQMLSRLPHLERYDANKAYDSDPMTSGYGQQAFVTTFFLGVQKNATDDRKRCVMPTESAVLSSSLRIPDFSYFNKFQPWIYETVHFTVDKPWRGNTHPDHPFVCSMLREWNESMQGVEKYYDLVPPIENDYLRNCGNSSSRAAPEQEGKAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5T9</accession>
    <name>A0AAD8Y5T9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009502</name>
        <name evidence="3" type="ORF">QTG54_009507</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5T9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="296" mass="33156" checksum="CED6B46F1600CBC0" modified="2024-05-29" version="1">MNNNQADSIVVSNVSSAIVTAAKSFAKRHKVITFSYVYGMSILCAIVLIGSGTKLTFDQQRQYNQIMNSIDLQAEYTAASKYHTSYANYYQSKGWFSCDAHCQHYKSIMDRRKSEWEEIKAEGNARMSDAKSVAGLFSEVGVTEVKDSFWDYFNSGKQFAKRQSWWDALFMGMRSMSRDESFIEYGLKMLMQVLINFSMGLIMALFIFIFGLWGIISSYQANPLTALFFFVSAASAAFAFVSTYLFAIYGAAAGGVVGVVKMAESNMRIEAARGGGGGARVRNGYVERNRNRPHYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y616</accession>
    <name>A0AAD8Y616_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">GABA-B receptor-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_009283</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y616"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038039">
        <property type="term" value="C:G protein-coupled receptor heterodimeric complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004965">
        <property type="term" value="F:G protein-coupled GABA receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15047">
        <property type="entry name" value="7tmC_GABA-B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.50.10">
        <property type="entry name" value="Tumor Necrosis Factor Receptor, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002455">
        <property type="entry name" value="GPCR3_GABA-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017978">
        <property type="entry name" value="GPCR_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519:SF20">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR 156-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519">
        <property type="entry name" value="GABA-B RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00003">
        <property type="entry name" value="7tm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50259">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="609"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="650"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="690"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="730"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="792"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="826"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="854"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 3 profile" evidence="11">
        <location>
            <begin position="682"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1013"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1058"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1031"/>
            <end position="1040"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1740333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1092" mass="119085" checksum="05B6A54A4F747E6E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y634</accession>
    <name>A0AAD8Y634_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">2OG-Fe(II) oxygenase</fullName>
            <ecNumber evidence="9">1.14.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_009652</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.-" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y634"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031543">
        <property type="term" value="F:peptidyl-proline dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071456">
        <property type="term" value="P:cellular response to hypoxia"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051559">
        <property type="entry name" value="HIF_prolyl_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12907">
        <property type="entry name" value="EGL NINE HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12907:SF26">
        <property type="entry name" value="HIF PROLYL HYDROXYLASE, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0847">Vitamin C</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="8">
        <location>
            <begin position="123"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="46"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="265"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="57"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="265"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="290"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1739893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="302" mass="34057" checksum="5DD6FCC645A9CE68" modified="2024-05-29" version="1">MASPPPPPIDTSPIPEGRVSITPNLLSKQQVEELLNDAKNLHRKGVFVPGGLRRRKNTDVHRNGTSADDMKTTTDATTRICDICGIFDDAEAAGPSDARDDLLDLMGDLRELLQLDLGVRLSESMELQYLRYPGGDGSSKKKKSGFYGRHFDSSPEDEKTCRRKVSLLLYLNDETWDVKKDGGVLRAYLPRQQLLQQESKSVKKRKRNSDGLVEEGVGTQDITPKGGTLVLFDSASVEHEVLPTYRERWAVVGWFLGEDISTVERRKNHRLEGQKRSSQPSHHSGEDQQRRKKKKKRRRRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8G1</accession>
    <name>A0AAD8Y8G1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8G1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36897:SF2">
        <property type="entry name" value="OS10G0350800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36897">
        <property type="entry name" value="OS10G0351100-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="350" mass="37740" checksum="B761A052C9F08FE5" modified="2024-05-29" version="1">MKSYTAAIIIGTITTQQSAAFQPSISRRALLSNIATTAGAATVLVPTLASAAEPKAGKKELLRGGKNASDALHNGTDLNPKEGAVAASLMEKMGMASDSVQGSDPSPDGVKNLESLLADAKVFTPVLGMGQGSAAFSSISTPRTAHKVRISSLLMMSADVESETTIADIEEITTFASKNGVDLKFTTNPTRGYRGVAVSKKDPENILGYIEGFIRPAGKVLHADKMEIFKSALYSARRENDSFTGGGTYLGPGLLIAFVCLLHGIENGCQTIEFLAIDDAEFQHKRLIRYYKTAGFEEVRYVGEELKDIPDRLVWGGCGTLMTNDIEQVLQKWTRIIRGANRRMERENNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8X5</accession>
    <name>A0AAD8Y8X5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Histone deacetylase</fullName>
            <ecNumber evidence="7">3.5.1.98</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_007265</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histone deacetylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8X5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141221">
        <property type="term" value="F:histone deacetylase activity, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040029">
        <property type="term" value="P:epigenetic regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF17">
        <property type="entry name" value="HISTONE DEACETYLASE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="6">
        <location>
            <begin position="71"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1741692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="386" mass="42389" checksum="2C636902D5A8F7A7" modified="2024-05-29" version="1">MSDAVRNYLPVKVISVDSETKSEQNDVDRHNKPRLRRSLIISAFIEKYSHLVQVINAPVSSNCDLVGLYSSVHDVGMIQFLVNSWSKWKAMGPDWDSDCCQPGWKGNIPPPLVPCHAAFRRDGIERVSSNVMGAFGYYCTDSLTPIVESLVTELQEDASIICEAVNLALLRNSVVYAATTHPGHHCNFDNFGGYCYLNNAALCARLMQKRLDDTAGNRRVAIIDIDYHCGNGTASIFYRVPDVFFTSIHCDPEIEYPFNAGYEDQIGEGAGKGATLHVPLAPGATWEDYKPALEKAMNAIMEFDVVGLVVSMGLDTYEGDSVSVRKGGFKLKGNDYVELGKTMGSYMKDNFIPTVFVQEGGYKMDVVGEAAADVLGGFSEGTRKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9R4</accession>
    <name>A0AAD8Y9R4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_006707</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9R4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052394">
        <property type="entry name" value="LRR-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114">
        <property type="entry name" value="LEUCINE RICH REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1742142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="275" mass="31020" checksum="7C21F643A115250E" modified="2024-05-29" version="1">MSFTNNDSGNNVPAGMSVEAILDIVESNKHLRKLEIESNRIGRDHIEKLCSAVHNHALLELSLFSSFEPGIGNEMLTSLLSIDGLKLEKLDMSSSNITSAVGMLLSDFIETNPRMRELNLRHNDLDDRDAALIANALRSNSTLRNLDLYRNSITEVGAECLRLVLCDESSLNAAADSNHNCNVRVRWDSIDDNSHEQGQINRGRKIYSILSKRNETMSNVQHFGDIDVKILPNILEAVQKYATKVHEDEDNPKPKVKPLSIVYETMRKWEKAFYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YA19</accession>
    <name>A0AAD8YA19_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006857</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YA19"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041981608" description="Transmembrane protein" evidence="2">
        <location>
            <begin position="28"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="193" mass="21857" checksum="16AB20FD7A25DE17" modified="2024-05-29" version="1">MKPRSISTTRALLSLFAAMLLAWNAHGFCTSTYRYRASKFLLLHHESDNNNNDDINPTKNKEKESDGNDNDSYSWAELQADEKLRQSELQKSINRRNNMLLPQRISQAVTTLGWTFVVTGIVLNSLGFAWVKKPEGGLGIGTLDQRNFQRELYRRSDDSAKDANNMISRASGAASEGYVRKWISFADDEQESC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAK3</accession>
    <name>A0AAD8YAK3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_006270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAK3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1742673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="104" mass="12210" checksum="8C5C2A68F20BB940" modified="2024-05-29" version="1">MIDGWTNESNNDYLDLFNVDKNLEKVNSRSTRNHRRWIPDHRLSVFTWDEACEYPLPEEYRLKGEPSDEDEADYGTYGDTCSEIMILNLFNDLEDLLGDLSSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBI8</accession>
    <name>A0AAD8YBI8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007613</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBI8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="290" mass="31345" checksum="F3AA37055BE1E333" modified="2024-05-29" version="1">MTAADTPASEEPQAPTTQQTSTIGNSRRRSSTNSLAGSRRSSFARRGSALFAAARASFVRTRGQSGASVEQLRGTSGSKYEGYANIHRGDGDFDAFNIFSLCCGNKSELYFVLIKGFHCFVFENEDSKSPKYAIELINRKAVIQPSHDTIIPRVPHPGAAHDTGYTTVHLETSLGDVEYKFTFANMENTASEFCNSVAVASNDASTEQVRKRLGHENLLSKRASMKFANAVGTAKAKDQPDAPVGAAEVMAGMPATGPGREGFKRWKQTITMILHMEKNGEGGVGNQMCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBT2</accession>
    <name>A0AAD8YBT2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Iron-sulfur cluster biosynthesis family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006490</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBT2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044200">
        <property type="entry name" value="At5g03900-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47380">
        <property type="entry name" value="OS02G0533000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47380:SF4">
        <property type="entry name" value="OS02G0533000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041974142" description="Iron-sulfur cluster biosynthesis family protein" evidence="2">
        <location>
            <begin position="32"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="439"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="482"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="593" mass="65442" checksum="9348B3E5FD5ADBA6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCH4</accession>
    <name>A0AAD8YCH4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Autophagy-related protein ATG18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_006617</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat PROPPIN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1743020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCH4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048720">
        <property type="entry name" value="PROPPIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11227">
        <property type="entry name" value="WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21032">
        <property type="entry name" value="PROPPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="503"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="594"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="631"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="52"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="135"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="503"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="595"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="637"/>
            <end position="646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1743020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="696" mass="74405" checksum="58297DBF8D90F602" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCI0</accession>
    <name>A0AAD8YCI0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006539</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCI0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042049459" description="Secreted protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="205" mass="22969" checksum="D86A24BA2C8B7650" modified="2024-05-29" version="1">MKFIKIATISFLAGNAAMVSSTKTTKSGKKECYFDAVTESYIKGSADNPVDRDGNQYFWGVNAVCKDPTFVYDPNVKGTASYCNDKNADEQYPNAVQVGSARGHCFVAPTQFGDNECQQEGLYGCEWNCEEVLVVNEDYLFLKYLYQDDDSSVMGDSLEYPREFKVIVTGGTGCYQNVDNAIIPGYTEYSDTYYYTYDLSPLKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2024-10-02" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCY2</accession>
    <name>A0AAD8YCY2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1743933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="9" mass="1097" checksum="6B9FD9D5B864140B" modified="2024-05-29" version="1">MERRGSFQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD23</accession>
    <name>A0AAD8YD23_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Syntaxin-5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_005848</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD23"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15844">
        <property type="entry name" value="SNARE_syntaxin5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF3">
        <property type="entry name" value="SYNTAXIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="444"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="11">
        <location>
            <begin position="372"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="30"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="276"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="403"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="296"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1743227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="464" mass="49239" checksum="6B1F83A0B8D4864E" modified="2024-05-29" version="1">MADRTNEFFAMANAIPATGAMTSIRGGATTTSASLSASSPQLAGDSMSNRHSNNAANNNNNKAASSDPAMAELRLFRTTASEISRDVSTTSALLAELSRLVKTGAGGTRMFADESANERADVLVLRIKSNIEGLHSRLEEASVVLERSKRRLGKNSQAGMEASNLVGQLKEDFVRTTSGFKAVLEERSDGMKDANQRKRRVFGGDGGGLDGQNGGGDEELVSLMNKPAVYGGDQRTSSFGDMGGMSGGLGGGRGMNNTSMGLDLTSGMMSMTQRHQDEMGGLPAGESSSQLPRPHGLGGAYGGGQSDGLRLRHSSSAPFDGGGGGSMPTFSGGASSYYPDSNQSHAPMTPMEIQQMESNMGTQSQMQLIPDQDYLRQRADAMSQVESNIVELGTIFNKLAVMVNEHRDMVQRVEDNVEDANSNLNLSLATLTDTLQNLQTNRALAMKVLGIVVLFIMMFIIFFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDV4</accession>
    <name>A0AAD8YDV4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_003990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDV4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="169" mass="18266" checksum="15AB7F22BAF8169D" modified="2024-05-29" version="1">MMSAPLCTKLMHGLVRVTCKRVTARAATSTSSISRMAFSSSGYGESITYSGGQASEGQGGFYGSGGARVSKIETEHKPEMMALAADVENLTLVMQEMCKLEEMLEEEKEGNSGVTGKSLEISSKIKKIMTSSDVMDCLNRLEVEGEPVWGLSSEERDLVHAARQKVNEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDZ7</accession>
    <name>A0AAD8YDZ7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005645</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDZ7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="46"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="166"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="95"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="113"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="324" mass="36612" checksum="DC5832D7C90B592B" modified="2024-05-29" version="1">MEENNNNNSHRRDDATKAILSRISNDNQLIEEVRQLLAENLQLRKSNNNDSSNINDTTVANSKDDGTSVAPTASSSLSSDVVVVMNNDTHKKLPTSSSSSSDGSKTQTSQRHNNAHYPHKHPRSKDDEELAFTIDKDSETYGNILSMAKWYRDSFFISANYANDNQQLRTRELEEAALRRKELQEQLKQKKKKNRRMSNTNTLRRYRPQIGSIMSLNDGPPLSSTLAMGHPLLLSIGENYIRSTYAVDLLRPYATWIVSKNGPLLTTASQSLAQTIPLGQASCDWAARDNLLWLLQDQEWRDFAKSITTRYINVDETNDGYDDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFD9</accession>
    <name>A0AAD8YFD9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004604</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFD9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="267"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="305" mass="33677" checksum="B358367B22F66D35" modified="2024-05-29" version="1">MTTSSDHCSLKSATYAAAVYDSSSSKISCRPRRTKPSPKTVADATNTNKAMVLLSLLTMLCMSPLATAQQECSCAPREYRFRLDFSGTCPPQTPPFPPNDYFGSGVKDYTCSIGDSPVQETVREERNPIRRRLDTLEGEVKVDDTQQGNPIESVLREANKNDGETVRFISSIVTKPEQIPYRITMILRGFNRNQQAIQNTFTIAFTNTCGVPTFTEGERIGWVIFDELIPASDETCPALPLPSRRPSSYYPPRSSGYSSKGSKKSSKATSTYGSSKSGKSKSRKSGKSKSSKRRHRNLRASGLHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFG2</accession>
    <name>A0AAD8YFG2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003478</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFG2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="290" mass="32678" checksum="F2C93BD332B6673B" modified="2024-05-29" version="1">MKPLESALRRKFTRVTAFEEDFELAESSDYRSKTPAADEEGLKLPLAGDGRPKFPITSQLDDSGNSRSTATPQMALSFESLEEEKRPIRTVTWNVEEVKKEEEDQEETLSMLGRRKYKAWRKQVNVEMKAKEQRSLKVWFWSHGCPCGDWSPMYLFRSDEESTVATSKCDESATGTYQSSVATSTFVTLDEDVDDDSTIPSFSRVGSTLDESIIEDDTIISDVSSNSSDGTMDSEIEEELEIQATPQPPKLEQPKLAPPIEVNIVKDWSREGLSTHTIGDMDLFMDAMRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YG41</accession>
    <name>A0AAD8YG41_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Long-chain fatty acid CoA synthetase</fullName>
            <ecNumber evidence="7">6.2.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_004111</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15421"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57560"/>
            <dbReference type="ChEBI" id="CHEBI:83139"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.3" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YG41"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF83">
        <property type="entry name" value="ACYL-COA SYNTHETASE LONG-CHAIN, ISOFORM J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="6">
        <location>
            <begin position="14"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1744820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="450" mass="48497" checksum="829CF9129217E732" modified="2024-05-29" version="1">MTLSVLVTPSIPFSPPHPDTCAVIMYTSGSTGKPKGVVVTHKNVLATTSMVAEIVDENDVFPAFLPLAHIFELVAEVSCIGMGACLCYADPKTLTSTGAYPIGALEQYRPTLMVAVPKLWDLIKKGIEAKIAAGSPVKQYLCKTAIETREVALKFGFDTPLFKALVFKKFAAVTGGRLRLAVSGGGPLNADVQRFANVCFGCPVGQGYGLTETCAGLTLQDVKDDRCGIAGAPIPCVEVKMVSCPEINDKAGLPYLSSDRKDANGNPVFGRGEVWVRGANVGLGYYMMPEKTKEDFDEDGWFKTGDIGQFADDGSVQIVDRKKNLIKLKGGEYIAIENMEMCYNNSSFVDAATGGVCCYGDGDMDRPVAVIQLNANTVKNWMKQNGITDDISKVNESKALYDAVLADMVKLHKEAGLGRNEKLVAIAFYLILGLLRMDALPPQTNFRDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGC3</accession>
    <name>A0AAD8YGC3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glycosyltransferase (Family 92)</fullName>
            <ecNumber evidence="10">2.4.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_003531</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 92 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="10"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGC3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008166">
        <property type="entry name" value="Glyco_transf_92"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21461">
        <property type="entry name" value="GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21461:SF69">
        <property type="entry name" value="GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01697">
        <property type="entry name" value="Glyco_transf_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="52"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1745607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="937" mass="106183" checksum="82CB378CDFCBA3C5" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YH72</accession>
    <name>A0AAD8YH72_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 subunit J</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_003121</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YH72"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.60">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023194">
        <property type="entry name" value="eIF3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013906">
        <property type="entry name" value="eIF3j"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21681">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21681:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08597">
        <property type="entry name" value="eIF3_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1746514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="261" mass="28961" checksum="F3DB73B3431AAFB2" modified="2024-05-29" version="1">MSDWDDSDDDWDKSDDELDKRLGLTKIDDAPPAFDDEDEDLTVKEKERDAKASAQLNKQKGSALAKKKAAEAAAKDELELAKKAMQLEAKMEANMTAEERRLLERERQEADAMAMADDLFGGVDNAGPSGPGGPGSVMMSGDKVVMKDLKDHLRHAKKVGECIQGHGKINLCAEFLKEVISQCKDVLDDDAITDVIKTCNVIKNEKVQQSKRKVKGQAQKSKKVDKQAKKKALEIHNDVFGDNDNYDDYDDMGGAYEDDFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHV0</accession>
    <name>A0AAD8YHV0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Peroxisomal bifunctional enzyme</fullName>
            <ecNumber evidence="16">5.3.3.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">QTG54_003195</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.3.8" evidence="16"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHV0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003857">
        <property type="term" value="F:(3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004165">
        <property type="term" value="F:delta(3)-delta(2)-enoyl-CoA isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004300">
        <property type="term" value="F:enoyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000009">
        <property type="entry name" value="Fatty oxidation complex, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.50:FF:000006">
        <property type="entry name" value="Peroxisomal bifunctional enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006180">
        <property type="entry name" value="3-OHacyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23309">
        <property type="entry name" value="3-HYDROXYACYL-COA DEHYROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23309:SF49">
        <property type="entry name" value="PEROXISOMAL BIFUNCTIONAL ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00067">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="10 16" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-hydroxyacyl-CoA dehydrogenase NAD binding" evidence="15">
        <location>
            <begin position="321"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyacyl-CoA dehydrogenase C-terminal" evidence="14">
        <location>
            <begin position="506"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyacyl-CoA dehydrogenase C-terminal" evidence="14">
        <location>
            <begin position="658"/>
            <end position="745"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1746588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="764" mass="82298" checksum="86CC032259836518" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YI01</accession>
    <name>A0AAD8YI01_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bile acid:sodium symporter family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003354</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YI01"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016833">
        <property type="entry name" value="Put_Na-Bile_cotransptr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18640:SF5">
        <property type="entry name" value="SODIUM_BILE ACID COTRANSPORTER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18640">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 10 MEMBER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13593">
        <property type="entry name" value="SBF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="261"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="285"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="320"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="391" mass="43073" checksum="B686C4401D7A7D7C" modified="2024-05-29" version="1">MSNERTPININTSVVGVSVHALHSLENNLNPVQENAASDNNASPPLHKRIWSKCQSIYGTHSFLSKALILILIAFAYPPLGATYLAPQITATWIAVIFIFVLAGMGIKTEEFAKAFQRLPFNLFVQLFNFGVVSSIVFGFSRLMVSVNALTQSLADGMTICASLPITINMVLVLTKSAGGDEASAIFNAAFGNLVGIFLSPALILGYLGVTGEVNMGQVFFKLGLRVVLPIFIGQILQHFVPPAKEFVKQYKKYFKTAQECCLLFIIYTVFCKTFLQGMEAGVGQIFLMIALQFFMLCVVMVLAWTCLRVLFRNEPKLQAMGLFGCTHKTVAMGVPLINAIYESNPMVGLYTLPLLIWHPMQLVIGSFVAPYVAAYVKRREEEISSALQEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YI33</accession>
    <name>A0AAD8YI33_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Anaphase-promoting complex subunit 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_002293</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YI33"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097602">
        <property type="term" value="F:cullin family protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16456">
        <property type="entry name" value="RING-H2_APC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000552">
        <property type="entry name" value="Anaphase promoting complex subunit, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051031">
        <property type="entry name" value="RING-box_E3_Ubiquitin_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024991">
        <property type="entry name" value="RING-H2_APC11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11210">
        <property type="entry name" value="RING BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12861">
        <property type="entry name" value="zf-ANAPC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="74"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="13"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1746949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="153" mass="17028" checksum="A283BC9625BD585D" modified="2024-05-29" version="1">MDPPPPRRRSPRYHNQLSNNNSFSSPGKKTNSSSNAGTETKLKIKIKRYHGVAKWTWGVSGFNNDDDDDEDEVCIVCQSAFEGCAPGVKYPGDESPVVFGKCKHAFHLQCVSTWLQSQNSNNPTCPTCRQEWEFGAERTVVDDDAEGEESVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJ40</accession>
    <name>A0AAD8YJ40_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2',5'-phosphodiesterase</fullName>
            <ecNumber evidence="3">3.1.13.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002738</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.4" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJ40"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004535">
        <property type="term" value="F:poly(A)-specific ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000288">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF37">
        <property type="entry name" value="2',5'-PHOSPHODIESTERASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="582"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="235"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="966" mass="106894" checksum="720EDC6BD38632DD" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YK93</accession>
    <name>A0AAD8YK93_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DOMON domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YK93"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="109"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="392" mass="41326" checksum="A32AF72DB80FE880" modified="2024-05-29" version="1">MTVMCFCYLFSLVGVFAVGFWAHMEFFAYKDTDTTMNKNIGVSQGTFENSPESLGASDATSMLRPPSSSSSSSGPTSSAKFQPLPTDGGLGTKVSQIPAVASNNPSSAPTPIVSDSPSSTPTSSSHPTSTPSISPSNLASESPSSEPTATRSESPSSSPSILDECPETLSRSMPFISDTSLTLYYETVIYQDHPTGGLLCASLEYSGAAGWIGIAFSTAGRNPQFGRREAIIGMPGVDTSIAVSAENVTSSALNPSGSQNNFVEGGPYFVNPAKYEIPAGGLDGYYGPSLGFLMSASQQTLVNASVTTSDDSNQTVTRLSFAKYLREPGEIEINPMSGPTLILYAVAPIDTSSGLYINENPQWKYINMILGGGRSNTRSSLMRKRQQNNPGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKL3</accession>
    <name>A0AAD8YKL3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein kintoun</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_002336</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PIH1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKL3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050734">
        <property type="entry name" value="PIH1/Kintoun_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012981">
        <property type="entry name" value="PIH1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22997">
        <property type="entry name" value="PIH1 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22997:SF0">
        <property type="entry name" value="PIH1 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08190">
        <property type="entry name" value="PIH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PIH1 N-terminal" evidence="3">
        <location>
            <begin position="250"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="165"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="413"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="25"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="165"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="192"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="444"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1746992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="526" mass="56730" checksum="F7815B61536FC539" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YL28</accession>
    <name>A0AAD8YL28_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002439</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YL28"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="117" mass="12976" checksum="5A83D576B29B26CD" modified="2024-05-29" version="1">MENEEEDTPTNAIDTSAGTEITQERCRSWSGTVLAALFFAYGGMVAVSVVFESFHVQMNLLVQMILLVGIFAVLALFVMVVMEKDMRRVELGPPQLPKDKESASDTSNSVKEMIERT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLD2</accession>
    <name>A0AAD8YLD2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Acid phosphatase family protein</fullName>
            <ecNumber evidence="1">3.1.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_001268</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLD2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010036">
        <property type="entry name" value="MDP_1_eu_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17901:SF14">
        <property type="entry name" value="MAGNESIUM-DEPENDENT PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17901">
        <property type="entry name" value="MAGNESIUM-DEPENDENT PHOSPHATASE 1 MDP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12689">
        <property type="entry name" value="Acid_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01131">
        <property type="entry name" value="C1.5.2:_MDP_Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="195" mass="22432" checksum="70BB4630CCBA7434" modified="2024-05-29" version="1">MQLVFDLDYTIWQPEMYQIDGPPKLISVDEFQGKQKRKSRAPPRSIPFGATTIHQNKIATDRRGIPITVFDGASHALSEINRMKKEDWPLQAAISSRTDEPGWAFQLMKWLVASDGTPLSKCFDENLIEISYMDKSKHFESLNRKTGIPFEQMVFFDNEYWNIQSVSSLGVKCYHTPDGMTKEAWVQALEDFGMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLR8</accession>
    <name>A0AAD8YLR8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">G protein-coupled receptor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_000262</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLR8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038039">
        <property type="term" value="C:G protein-coupled receptor heterodimeric complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004965">
        <property type="term" value="F:G protein-coupled GABA receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002455">
        <property type="entry name" value="GPCR3_GABA-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000337">
        <property type="entry name" value="GPCR_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017978">
        <property type="entry name" value="GPCR_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519:SF20">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR 156-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519">
        <property type="entry name" value="GABA-B RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00003">
        <property type="entry name" value="7tm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01176">
        <property type="entry name" value="GABABRECEPTR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00248">
        <property type="entry name" value="GPCRMGR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50259">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0807">Transducer</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042124802" evidence="11">
        <location>
            <begin position="29"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="528"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="562"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="615"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="657"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 3 profile" evidence="12">
        <location>
            <begin position="611"/>
            <end position="715"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1748323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="715" mass="76614" checksum="7709724592AFFEF3" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLU6</accession>
    <name>A0AAD8YLU6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Ribonucleoside-diphosphate reductase</fullName>
            <ecNumber evidence="3 12">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_000910</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 12">Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 12">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + [thioredoxin]-disulfide + H2O = a ribonucleoside 5'-diphosphate + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:23252"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="EC" id="1.17.4.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer of a large and a small subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the ribonucleoside diphosphate reductase large chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="3 12"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLU6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005971">
        <property type="term" value="C:ribonucleoside-diphosphate reductase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009263">
        <property type="term" value="P:deoxyribonucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01679">
        <property type="entry name" value="RNR_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.70.20:FF:000010">
        <property type="entry name" value="Ribonucleoside-diphosphate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013346">
        <property type="entry name" value="NrdE_NrdA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000788">
        <property type="entry name" value="RNR_lg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013509">
        <property type="entry name" value="RNR_lsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008926">
        <property type="entry name" value="RNR_R1-su_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039718">
        <property type="entry name" value="Rrm1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02506">
        <property type="entry name" value="NrdE_NrdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11573">
        <property type="entry name" value="RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11573:SF6">
        <property type="entry name" value="RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02867">
        <property type="entry name" value="Ribonuc_red_lgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00317">
        <property type="entry name" value="Ribonuc_red_lgN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01183">
        <property type="entry name" value="RIBORDTASEM1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51998">
        <property type="entry name" value="PFL-like glycyl radical enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48168">
        <property type="entry name" value="R1 subunit of ribonucleotide reductase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00089">
        <property type="entry name" value="RIBORED_LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 12" id="KW-0215">Deoxyribonucleotide synthesis</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 12 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-cone" evidence="14">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="766"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="766"/>
            <end position="784"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1748971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="811" mass="91139" checksum="79E640D3029CCA39" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YM19</accession>
    <name>A0AAD8YM19_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001048</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YM19"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00136">
        <property type="entry name" value="PDZ_canonical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1749109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="339" mass="37622" checksum="9B929A2C38F1AB0B" modified="2024-05-29" version="1">MFETTSITLTPRTRDQDVNITTKASSTPSPNAVQDFRNSAITNSNASDVVSDAIYEQLGVVVTDSEVIEYSSALALPELTEAYEHTDFEYDDSRENDLDTSEDDVTNRCSSRSRSRVSPTKTNMTTITVGQRMLQQALSSLATPVPTDAEFTAQINVGNERQVLFHALSLGVTLNRGIDGYVRVVSASKVDDDQVRDGDIFAGDIVREVNDVDLRMPIDMAVWKMTIALMKMAPRPLIMVLAEELTDQHADEEEINDSPATCDVIEAQSGEDKKYRSATRAFRHLMKRSSAVDPNKGMPPTLEELSEEHLTSIELDHSRDAWDDFDECMLTAAQMSNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YM31</accession>
    <name>A0AAD8YM31_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_001045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YM31"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1749106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="59" mass="6722" checksum="C754AA916CB2ADAB" modified="2024-05-29" version="1">MDLGSLQDMEAQIQFPTQFAQQGAPELLDPQGRLRQPGDLETDLIECWNDINKWSSTML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YM34</accession>
    <name>A0AAD8YM34_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Laccase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_001972</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1748009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YM34"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF2">
        <property type="entry name" value="MULTICOPPER OXIDASE LPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastocyanin-like" evidence="3">
        <location>
            <begin position="14"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="2">
        <location>
            <begin position="244"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1748009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="431" mass="46278" checksum="68B6BDC3555563DB" modified="2024-05-29" version="1" fragment="single">QFKLFRILSAHPPGTTYKLTLHNSADDSTLKTNIHTHGLHITGSGDGDDITRFVTGGGCLDYTWDIPSDHPGGTNWYHPHYHTLTNGQTAGGAFGMIIIDDDYSKVHAWAHPQNELLLLVSDIGNSVLGNGITNEVFQVEVGRWYRLRVSTVEPNANTAALSFNGGDCTVHKVASDGIWHNAALTTYSGSSFDMTGASRADYAISCASVGSTTVKWGSGEVATIEAGTFGSNTGSEETDLGNAPPKPASLTGLNDASVDGTFSITMSGAKINRKMWDEDVPLGVVPYGGIYEWTIGGTGAHPYHQHLYHMLIVEPGGCGFHQEGEFYDILSASGSCRVRFYAIDIGQRMVLHCHVLGHEDNGAMTWMDVTGTPSSNQNNVVAPAYQCSGGTPPPPTTTLHLHHPLLLLRLPSTIPSSYYGYPSTIPSSYCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMF0</accession>
    <name>A0AAD8YMF0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Aldo-keto reductase family protein</fullName>
            <ecNumber evidence="7">1.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_001225</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.-" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMF0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF3">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="6">
        <location>
            <begin position="105"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1749286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="384" mass="43166" checksum="E64D3A0E26E36E08" modified="2024-05-29" version="1">MKSFSLRSRPGGLSGGNRGPNDNSSKTHLENISDLREVKHNKQKRNIAPLIFKNRPRILVICFSSCVVLFFFFFLSHNLPVTNDEADSEDKKFAPMGTIVYGAKSKGDDTDKLVAQAITAGFRHIATGGFHFEYNEPGVGIGWKESGVPRNELYLQTLFVSKSVNNYGVQNCKVEGCPPSPDLSIEDQVHLSIKSSLHNLQTPYIDSVLVHNFRAKLQTYEDTMAAWRVLESYVDRGIIRHLGIVSVHDRDYLIKLHNETRVKPSIIQNRFHSNRGYDVELRPLFKDMGTSNQLFWILTGSAGGKVRNNNVITEIAQRQGVSNQILLYSFILVCLGGTPLIGSKTLLHMEEDVTALLRKPLIWNDEDFTAVANVINKNLIKNKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMV8</accession>
    <name>A0AAD8YMV8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SART1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_000101</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNU66/SART1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMV8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000481">
        <property type="term" value="P:maturation of 5S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045347">
        <property type="entry name" value="HIND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005011">
        <property type="entry name" value="SNU66/SART1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14152">
        <property type="entry name" value="SQUAMOUS CELL CARCINOMA ANTIGEN RECOGNISED BY CYTOTOXIC T LYMPHOCYTES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14152:SF5">
        <property type="entry name" value="U4_U6.U5 TRI-SNRNP-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19252">
        <property type="entry name" value="HIND"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03343">
        <property type="entry name" value="SART-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="29"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="72"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="153"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="316"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="375"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="578"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="669"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="105"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="175"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="318"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="390"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="411"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="434"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="463"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="493"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="669"/>
            <end position="682"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1748162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="842" mass="91668" checksum="DF426C1DFE156DB0" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YN27</accession>
    <name>A0AAD8YN27_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Trypsin-like serine protease</fullName>
            <ecNumber evidence="8">3.4.21.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_000080</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YN27"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000002">
        <property type="entry name" value="Transmembrane protease serine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000068">
        <property type="entry name" value="transmembrane protease serine 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF91">
        <property type="entry name" value="AT26814P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042238371" evidence="6">
        <location>
            <begin position="32"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="7">
        <location>
            <begin position="54"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="318"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="570"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="323"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="570"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="586"/>
            <end position="599"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1748141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="658" mass="72023" checksum="F890F8DE735B46FD" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YP97</accession>
    <name>A0AAD8YP97_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">E2 ubiquitin-conjugating enzyme</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_000836</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YP97"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23813">
        <property type="entry name" value="UBCc_UBE2N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000020">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="8">
        <location>
            <begin position="6"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1748897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="158" mass="17751" checksum="B078D758419699CA" modified="2024-05-29" version="1">MSNQSQLPRRIVKETQRLIAEPVAGISATPYADNLRYFAVSVEGPSDSPYERGVFQLELFLPSDYPMSAPKVRFLTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLDNTVAELWKTNEKEALRRAKEFTESFAMKGGSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3K9</accession>
    <name>A0AAD9D3K9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome P450 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_016937</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000068">
        <property type="protein sequence ID" value="KAK1732402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3K9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="419"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="636"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="438"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="455"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="3">
        <location>
            <position position="685"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1732402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="740" mass="83212" checksum="7CC9090DB69CF46C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2024-10-02" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3Z6</accession>
    <name>A0AAD9D3Z6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016214</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000054">
        <property type="protein sequence ID" value="KAK1733076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="2">
        <location>
            <begin position="304"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1285" mass="144201" checksum="8EC503B35AC76FDA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4A7</accession>
    <name>A0AAD9D4A7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015851</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000049">
        <property type="protein sequence ID" value="KAK1733436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4A7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="386" mass="41913" checksum="7ED36219F3AAC0B5" modified="2024-05-29" version="1">MSTVALSNGTILAAAFGGNGGGNSSYCSALGGMGGRLRGMNNEGFVNPELVLVDNAVEDAIESDINGSSLALQETIAPSMPQNQWIPVTITEEMTTFAEANTTNATWCEHSNHRPTGRRGHSMTVVNNHVYIFGGALLKCLCTVVNDKKQCSSKNIYSSELWHFDVSSSVFTLLEPSGEEELPRGREQHSATALPNGDIVIIGGLSSSSSSLDEAITEDLEPMNEVWKLSDPHRVTSHVISGGDSSITQLPMELNQSYLSSHTLTVDLGHDICVEDLQLSLSLDHGCPQGIEFISLTGPPAPSNQDSIQSRHYQTKLFVSTAENRERDYHSSQFDLLFSDASEEAVLSYSGCQTQVPTVLQVVSKKHSKAWPLMENGRWQFPPQRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4V6</accession>
    <name>A0AAD9D4V6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015384</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4V6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="48"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="118" mass="12679" checksum="0D9E1348A2869251" modified="2024-05-29" version="1">MDGSANDQVITKLSTRVHELFPLRSDADELKDFVTSSIESIAGGGAVVDKESVAKGMKWVDDDGDGHISKKEVAKYYNLAGKKFMEISKTIKQLGPMLAMFGGMDMNGGGGDGFKMDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D657</accession>
    <name>A0AAD9D657_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Gamma-glutamylcyclotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014847</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D657"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35748">
        <property type="entry name" value="OS05G0358400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35748:SF1">
        <property type="entry name" value="OS05G0358400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="238" mass="26371" checksum="B322D75CDD5E62B5" modified="2024-05-29" version="1">MTITIPPALSGPSQVVTLLGYGALLSESSSRLTFPDLSNFRHVRVKHHKRVFAHPHLFLIKEGLVDPISSLELASLSAEPSDDDSSSFIAAAFDVVLTDERVDFVKREPEYDIVSTPYYDINRHDDGNSQPVGSGIICLASKDSDMRDIDHLHAISTKLKDKGGIWHWPCDSGLLPANIYLRHCLLAVQKAGGVAYSSFLEDTYLVDRKTTLKEYLDKHEDMVMASRPPPHLATRFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6F3</accession>
    <name>A0AAD9D6F3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Plastid lipid-associated protein/fibrillin conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014466</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6F3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042172286" description="Plastid lipid-associated protein/fibrillin conserved domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="287" mass="31795" checksum="03C301C9B3F3C7A6" modified="2024-05-29" version="1">MTRSVSLSLVAVLAIAGSGTSFTLPDASTIRSHNFSPLHSTVSQEVPASPWFTDDENTNQSTQKLKTQFCNWERHLIEVNHTIQPAEITTLSNCLVGSRNNVPKSLDDIAGEWELVFTTVKHGIFRSSPFFLAVQEAFEYSEEKEAFGEDKATLFFKLHELQTCSWGASKIGRVAQRIDPKTGYLYSEFDTSIFSLTVIPILGWFKLLPTFGGCVVTASKAKLAVGGVLEMEVDYTTSRPVPGLQGLGEWIWSVKVPVGAVWKFLPWNKGRSADCSVTVKYVDEDFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6P6</accession>
    <name>A0AAD9D6P6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Translin</fullName>
            <ecNumber evidence="3">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013389</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000031">
        <property type="protein sequence ID" value="KAK1735942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6P6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14820">
        <property type="entry name" value="TRAX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.200">
        <property type="entry name" value="Translin, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016069">
        <property type="entry name" value="Translin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002848">
        <property type="entry name" value="Translin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036081">
        <property type="entry name" value="Translin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10741">
        <property type="entry name" value="TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01997">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74784">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042092443" evidence="2">
        <location>
            <begin position="20"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="543" mass="61049" checksum="1BFF692108D57960" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6X1</accession>
    <name>A0AAD9D6X1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6X1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1736391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="80" mass="9137" checksum="0BC4CA37CC439A5A" modified="2024-05-29" version="1">MVRRKMGFEYDSTMKFQGGEPDLDELDNAIQVVERLGYNCRVKHFFNNKNEVTFMVSEKDGNPLDLEVGSLGSTMFPVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7W6</accession>
    <name>A0AAD9D7W6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011787</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7W6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="205" mass="21918" checksum="410346CDF0F0E761" modified="2024-05-29" version="1">MNVPTPAPKVEAATAEAVTPKAAPLAEAPVESSVTIAERPANASYISAAPPPDASLTTDAEQDASEGIEMKCDDSSKPSVEVLRATGKILFEGYAAVIIGPVQKNICEKALKCFYDERSFLSYGEGQYNIRICDADMPSPMYTIPLEDLELEKEDPQNPHFFSHTISPEASAGILGEPFSNNKSKASLDTVLLIDGVEDCISTCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9L9</accession>
    <name>A0AAD9D9L9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Periodic tryptophan protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_010483</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9L9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044285">
        <property type="entry name" value="PWP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14091">
        <property type="entry name" value="PERIODIC TRYPTOPHAN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14091:SF0">
        <property type="entry name" value="PERIODIC TRYPTOPHAN PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="337"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="389"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="32"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="307"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="603"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="167"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="150"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="318"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="615"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1739167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="631" mass="68752" checksum="6CB8FAB9131D229D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9P2</accession>
    <name>A0AAD9D9P2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Adenylate/guanylate cyclase domain-containing protein</fullName>
            <ecNumber evidence="10">4.6.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_011308</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.-" evidence="10"/>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9P2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004383">
        <property type="term" value="F:guanylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001653">
        <property type="term" value="F:peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007168">
        <property type="term" value="P:receptor guanylyl cyclase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050401">
        <property type="entry name" value="Cyclic_nucleotide_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920:SF335">
        <property type="entry name" value="GUANYLATE CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920">
        <property type="entry name" value="GUANYLYL CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="9">
        <location>
            <begin position="519"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="41"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="93"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1738014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="726" mass="80056" checksum="C33529699C5FB026" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBS8</accession>
    <name>A0AAD9DBS8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008973</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBS8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1140.10">
        <property type="entry name" value="Cyclic phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="LigT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="298" mass="33343" checksum="936E07CA6F7B7E39" modified="2024-05-29" version="1">MSSTTTDQMDGLPVVSKLYLSASCPELKAESVISDFSDTEEILSDIERVVTPPIQEEQEEFIIESTSLPSPIPLSRIGLPTTTTAAGLAIPTALPSSSPLSSRRSLEWQFKGLTVWLELEEFDNDLTRAVEYFSSKHNSPFIPQSHTTAIYGMEHLSIEEARARLRTVRDLIPQWPTFAKPTGITSDIAQCGRPGQVCDIAWSELTLATNPQHEAALDILYELFYGSVYHRDRPWKPHNSVAYDNPETNHLSLLDTIMYASQNPSLLGMERRVAAIALWSTVGKMGDWECLERVRFID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCW6</accession>
    <name>A0AAD9DCW6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Bifunctional lysine-specific demethylase and histidyl-hydroxylase</fullName>
            <ecNumber evidence="3">1.14.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_008385</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="3">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ROX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCW6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051864">
        <property type="term" value="F:histone H3K36 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032453">
        <property type="term" value="F:histone H3K4 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039994">
        <property type="entry name" value="NO66-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13096">
        <property type="entry name" value="MINA53 MYC INDUCED NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13096:SF8">
        <property type="entry name" value="RIBOSOMAL OXYGENASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08007">
        <property type="entry name" value="JmjC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2 3" id="KW-0408">Iron</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="JmjC" evidence="4">
        <location>
            <begin position="40"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1741133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="411" mass="46639" checksum="4DE1CBCF72B8B6C8" modified="2024-05-29" version="1">MEDLGGNQDEHGYKQDVHSFQAKRLDWKEDILNATNTIIFNSAGSYISSTLAATSLAALHGLDGASAGVCMNLYVTPAMVQTSAPPHTDKQDVVVVQTQGRKRWRVYSPPDSSFDSELDPFKGMLERENSELLLDVTLYPGDTLRSFEKEDWSMHLTVGLDSHVWNLNYISMRTLALRSHGIHDVLLQQTAQNFDRNMDMCVGRVNQLSNDLREGLYSSVDDTMLSFHSKNDRTNLECGFREDEAQSLTFDQCLQTVNHFQYVGQKIANSHQDMYVAAVKEEQMRVNEEGGWARNVGNSMPDERARRLSIFRVPLYFQEMDMCREELRAWGDFLGTHENISPMILVGDQVESVFPTNLCREVDGEHPFNSAKVIKISSDGMLYDLQYFNGMVQKGVQEHYLRGPHGIGIYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DD86</accession>
    <name>A0AAD9DD86_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">R3H domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007956</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DD86"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02325">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="entry name" value="R3H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001374">
        <property type="entry name" value="R3H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13369">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13369:SF0">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13679">
        <property type="entry name" value="Methyltransf_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01424">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="R3H domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51061">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="R3H" evidence="2">
        <location>
            <begin position="542"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="609" mass="67591" checksum="9E437FD9E09D5645" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDB0</accession>
    <name>A0AAD9DDB0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sel1-like repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008048</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDB0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1741570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="209" mass="23346" checksum="CB2291FA38346035" modified="2024-05-29" version="1">MACCSQVICDGCDCANKIGEIEQSLQHRCPFCRHPAAKTEGEVKQLRMKRAEANDRHALLPMGYDLHQEEDYGSALAYWKKAAELGNAEAHYVVSNIYWEGKGVEKDIKKAIYHLEKAAIDGHPFARYNLGCIEGNNGRKDRAVKHYIIAASLGHDTSLEDLRECYAEGSVQKEDFAAALRAHQAAVDATKSLERDVAEAFYAENKEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDD6</accession>
    <name>A0AAD9DDD6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_005823</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDD6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031415">
        <property type="term" value="C:NatA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051556">
        <property type="entry name" value="N-term/lysine_N-AcTrnsfr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42919">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42919:SF8">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042213563" description="N-acetyltransferase domain-containing protein" evidence="3">
        <location>
            <begin position="31"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="135"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1743202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="253" mass="28681" checksum="331ABED3BC410864" modified="2024-05-29" version="1">MMARSTLKHSAARVAALFILFIQQLAASSAFVLNQRCAYSSAACQLSLESSDNIVIQQINQDNKDDLEEFSTFCIDIFHNNKGESDSVVSRKWKDIKLAMLQKAQMIDLSVPFNGNRSVFVARSCIDSDNDRLTEIIGCCEVIEERIAISQKQKSPRVRPIIENLAVNEEYRRQGVGKALLEACEQNVQTWIPFHDDIFAQVEDGNLKAKEFFMDNNFKVVYSDDDCKKDDLEGLAFSQTTITKFMLRKVLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDF3</accession>
    <name>A0AAD9DDF3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDF3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1741583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="71" mass="7802" checksum="8764055FD069399D" modified="2024-05-29" version="1">MKRGKANDPDAMRGVGFLSYHGGDYDSARDEADIVKVYNHLKEAAIAGHPIARHNLGVVELEIGREDRAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DE28</accession>
    <name>A0AAD9DE28_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ShKT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006883</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DE28"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003582">
        <property type="entry name" value="ShKT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01549">
        <property type="entry name" value="ShK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00254">
        <property type="entry name" value="ShKT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51670">
        <property type="entry name" value="SHKT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="ShKT" evidence="2">
        <location>
            <begin position="117"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="175" mass="20244" checksum="CF88452CC0E19326" modified="2024-05-29" version="1">MKIDHAEIKKRISVFALSLIIIHRIILLAAKGTPIASRTCVETEDNVYFCTDDLQEAREKSKKTHRYYLDNFGARQTIVGNSKDMEKMRIWESDMEVYLKKFIEERGDGEEWLKELCTNQHKNCIFWASKGECKSNPTYMEQNCTLACQSCHKLNQQHEGSCSCAAEQEFCNSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DE93</accession>
    <name>A0AAD9DE93_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004994</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DE93"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050769">
        <property type="entry name" value="NAT_camello-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947">
        <property type="entry name" value="GNAT FAMILY N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947:SF37">
        <property type="entry name" value="LD18367P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="194"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="851" mass="95146" checksum="6E3BE87F289AE3F9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEN9</accession>
    <name>A0AAD9DEN9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEN9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="832"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="836"/>
            <end position="847"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="916" mass="100834" checksum="90E3821AA2A96AD9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEZ4</accession>
    <name>A0AAD9DEZ4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEZ4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1743714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="273" mass="30693" checksum="7785955FBD0DB32D" modified="2024-05-29" version="1">MRALFISSIFTAPLHRFVVCYNLVPHDGRRSILKTRRKFVTFTTTSILSPLLLPLSDQNACAAEEYYSMSTIKETAQYIQKYTNENFLRSVMESDCNFLYRGLSPDANKQLVIENSSGLVITDEPFDLLDVETYGSNAAATYFQSLEVQMNANRLSIRPSNSHMGSTCPLEAAKWGTAVSIWPLGEHGVQFAWMDGGGLFWPVPASSKSRAVALSDGTQNDDRRLSEALRGDAWEIMFRADNGFLAVPAAFDDELKEILRQLYIERVHRIPMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DF09</accession>
    <name>A0AAD9DF09_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helicase-associated domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005356</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DF09"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.530">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005114">
        <property type="entry name" value="Helicase_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33418">
        <property type="entry name" value="HELICASE-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33418:SF1">
        <property type="entry name" value="HELICASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03457">
        <property type="entry name" value="HA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase-associated" evidence="2">
        <location>
            <begin position="115"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase-associated" evidence="2">
        <location>
            <begin position="192"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="312" mass="35796" checksum="E3C0D2A938DFC436" modified="2024-05-29" version="1">MLDHGDRLTVIAAAILEHQQLHPDMSKQESYNAIKNSLPASVTDGAKLLYQSMLDHGDHLTVIAAAVAKHQKLHPDMTKLQSFDTIKNSLPASVTDGAKRTYQSTIGDRAIGDNDEKWNTRYDELIEYKRVNGHCNVPRNDQANKSLANWVMKQRADYKKFAADNTTSMTQDKITRLDSLRFEWNGREASGDEKWNTRYDDLIEYKRVNGHCNVPYDYQANKLANWVKKQRAEYKKFFADNKTSMTQDKITRLDSLGFQWVMKKVAAKGSVMKTTKKKSPQKKKSSQKMKKKSLKKFPKKKGIETNSSKKTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DF25</accession>
    <name>A0AAD9DF25_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MHD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DF25"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MHD" evidence="1">
        <location>
            <begin position="58"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="328" mass="35997" checksum="8FCB6619F57A4C56" modified="2024-05-29" version="1">MSEAFDPFNVSDADDLFTATVAPTSAPVSPVKTRVPSFNIKPQYVAQDRAPPIVVLPKMDVKLKLHEEVTSKAVPGMGEDGTVELFVEGKVMAQAESSISKIPPFSLQITSPPSSECDIVYQNCCKVQTERKIQVSKQRSIRCKVDIPQPKAECEVLRYSMTAETKNMPLLVQSKASLKGNVCRVGIQIRSNLSNQGDINDLSISVPIPNTMQESTVKITRGADTGSWDECKRLVTWKIGTLPHGQSVLVSVEAEISHTMAQLVADDDISSTKFNEKIQCPVLIRCSSLSDTLTDFALSASPWMEDPSTLSLQQGQSYRLLLRVPTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DF60</accession>
    <name>A0AAD9DF60_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ferrochelatase</fullName>
            <ecNumber evidence="6">4.99.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_004263</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the ferrochelatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.99.-.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DF60"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004325">
        <property type="term" value="F:ferrochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00419">
        <property type="entry name" value="Ferrochelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1400">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001015">
        <property type="entry name" value="Ferrochelatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033644">
        <property type="entry name" value="Ferrochelatase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11108">
        <property type="entry name" value="FERROCHELATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11108:SF1">
        <property type="entry name" value="FERROCHELATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00762">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53800">
        <property type="entry name" value="Chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="3 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1744972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="500" mass="52895" checksum="471624735438EB56" modified="2024-05-29" version="1">MGQGSFKFSSRVGPVEWLRPYTDDVLPSLGEQGVKNLVVVPISFVSEHIETLEEIDIEYRELALESGITNWRRSPALNTDPTFIDDMADMVADALSEPSQTITEACVANNVGNLELEPVSNQLEISSAGVGGVGFDDNLAYSSKMRKDRLEARATKYPQQSKRKSKAFQCTYIAFSANATLQELIPIGIDLGRSRYTLALVGSDKMSGEDDNNSDAVRHIFGEAARRALARDKKPTISKDPSSMVQELVKSSSSVDGGDNNKSSAAAAFFGHLADLACDASSSHPSKLRAVVSVNVGASPEEQAGVVETIEAGVSEALKSRSDVKQKKKDVEPIVVGVITDPAAVCIAHGLTEVENSDAIDLAASNPDSWTNALVVDWGASGLQPHISGGKSADKAVGASTRKVKACPVNIGIAKSGDEENAVPLIEVGQALPANTTRNFTYNSGEEIVIVQMNGGAAKSSKVLGKIEKLPADKSFEITMELSAVGKLSLSVNGGPMSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFS6</accession>
    <name>A0AAD9DFS6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14 15">Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase</fullName>
            <ecNumber evidence="4 15">2.7.4.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">QTG54_005565</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>1D-myo-inositol hexakisphosphate + ATP = 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:37459"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="ChEBI" id="CHEBI:74946"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:37460"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ATP + H(+) = 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:10276"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58628"/>
            <dbReference type="ChEBI" id="CHEBI:77983"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:10277"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 15">Cytoplasm</location>
            <location evidence="2 15">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the histidine acid phosphatase family. VIP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.24" evidence="4 15"/>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033857">
        <property type="term" value="F:5-diphosphoinositol pentakisphosphate 1-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052723">
        <property type="term" value="F:inositol hexakisphosphate 1-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052843">
        <property type="term" value="F:inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006020">
        <property type="term" value="P:inositol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032958">
        <property type="term" value="P:inositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000036">
        <property type="entry name" value="Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11950:FF:000002">
        <property type="entry name" value="Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037446">
        <property type="entry name" value="His_Pase_VIP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040557">
        <property type="entry name" value="VIP1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12750">
        <property type="entry name" value="DIPHOSPHOINOSITOL PENTAKISPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12750:SF9">
        <property type="entry name" value="INOSITOL HEXAKISPHOSPHATE AND DIPHOSPHOINOSITOL-PENTAKISPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18086">
        <property type="entry name" value="PPIP5K2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00616">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9 15 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="17" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 15 19" id="KW-0808">Transferase</keyword>
    <keyword evidence="17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1708"/>
            <end position="1727"/>
        </location>
    </feature>
    <feature type="domain" description="VIP1 N-terminal" evidence="18">
        <location>
            <begin position="529"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="183"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="358"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="442"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="480"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="643"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="909"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1587"/>
            <end position="1620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="17"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="34"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="148"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="198"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="358"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="446"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="480"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="505"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="957"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="986"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1587"/>
            <end position="1600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00071668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU365032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF18086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK1743968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1733" mass="191351" checksum="F31CFA88283E22F0" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFW9</accession>
    <name>A0AAD9DFW9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WRKY19-like zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFW9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056866">
        <property type="entry name" value="Znf_WRKY19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24906">
        <property type="entry name" value="Zf_WRKY19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="731"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="756"/>
            <end position="768"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="884" mass="97563" checksum="4839C40FE3AE5DAC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG32</accession>
    <name>A0AAD9DG32_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Lipin/Ned1/Smp2 (LNS2) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003018</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DG32"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026058">
        <property type="entry name" value="LIPIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013209">
        <property type="entry name" value="LNS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12181">
        <property type="entry name" value="LIPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12181:SF12">
        <property type="entry name" value="PHOSPHATIDATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08235">
        <property type="entry name" value="LNS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipin/Ned1/Smp2 (LNS2)" evidence="2">
        <location>
            <begin position="204"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="341" mass="36697" checksum="B92E6C12B7386EFA" modified="2024-05-29" version="1">MTSTPPTSSSDPRGSSSGWALDVIIVAPAPKSANTGVAASSDFYVSFPSSLAKSRKNSFSNTTKRLSSFVSKKSSSNDVSESGEEDLISERTSSSMSAQTNNSSSAIPTPKGNVQVSINGRCIPKLDMTFSKKNTSSCRFVHGNSLKPSAETLNMIIDGTADIDESLETTCTCSEAVKNSEHHICAKNNKLSGGDQSKARPILLDSGRRNVITYTLVSEKGDVISYAKAYLYVWSALDSVIVSDIDGTVTKDNVGGVMDTVVQEKYAHVHNGICKFYQELTKISPVEDMDALNSSGNVEGQVRFMYLSSRPISLVNHTRKLLDKVTQICEAKNVIHCLKAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGJ7</accession>
    <name>A0AAD9DGJ7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine/threonine-protein kinase RIO1</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">QTG54_003019</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 20">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGJ7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05147">
        <property type="entry name" value="RIO1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051272">
        <property type="entry name" value="RIO-type_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018934">
        <property type="entry name" value="RIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000687">
        <property type="entry name" value="RIO_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018935">
        <property type="entry name" value="RIO_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017407">
        <property type="entry name" value="Ser/Thr_kinase_Rio1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45723">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01163">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038147">
        <property type="entry name" value="Ser/Thr_PK_RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00090">
        <property type="entry name" value="RIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01245">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 23" id="KW-0418">Kinase</keyword>
    <keyword evidence="15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9 23" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RIO kinase" evidence="22">
        <location>
            <begin position="142"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="124"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="527"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="21">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="21">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="21">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="21">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="21">
        <location>
            <begin position="551"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="18">
        <location>
            <position position="348"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="18">
        <location>
            <position position="365"/>
        </location>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="353"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="365"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="23">
        <location>
            <position position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR038147-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR038147-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRSR" id="PIRSR038147-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="SMART" id="SM00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAK1746412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="605" mass="67674" checksum="52B265028063E1E8" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHC9</accession>
    <name>A0AAD9DHC9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutathione S-transferase</fullName>
            <ecNumber evidence="5">2.5.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_003829</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHC9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051369">
        <property type="entry name" value="GST_Theta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43917">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43917:SF8">
        <property type="entry name" value="GH16740P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="3">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="4">
        <location>
            <begin position="76"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1745905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="227" mass="25597" checksum="9415DF4015066C8E" modified="2024-05-29" version="1">MKKEPFECISINPMKGENRTAEYRAQFPLGLIPAIEDDPGDGKTIALSEASAIMIYLCDKNKWNDMYPSSNNNPSDIRQRALINEYISHHNESTRLMTLKVIFPGLSGLFAAEGNLSPGMTHSLSSSPADLMKLKSTIRDTAKRFQHKFLVNSRGSSDFIVGDTPTIADLLAYPDLAQIPQILGIDYVEWPELEELRQWLDRMAKLPYHDDVHRTATKLGKLYQSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHG1</accession>
    <name>A0AAD9DHG1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">VTT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_002826</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHG1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015414">
        <property type="entry name" value="TMEM64"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="VTT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12677">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP38-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12677:SF59">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP38-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="VTT_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042211132" evidence="7">
        <location>
            <begin position="28"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="306"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="VTT" evidence="8">
        <location>
            <begin position="169"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1746219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="338" mass="36849" checksum="650BEA88176AF628" modified="2024-05-29" version="1">MAGRKATQQALLLIIGILLCPTNASSASSISLPRSSATKKHKLHRPSSFVHLKNDQLQLQQLGQFRGGALFTSKSNNNNDQEDDLLVLSTRNNNNNNNAAAIAKSVITTTSVIAIATFSFLHWDKIQAFFDREKFRTAIIQTLNDIASKGNKGLFLYAVGFMLWECCGLPTSVVETAAAMAFGFKGGLIGSFVGKTCGSLLAFTLGRTLLSNVVGEKMEENDLFGLVERGVQRHPVKSSLIVRYSPFPQLIKNFALSLTKPVTFPIFLLAISIHGFPFSLLWAALGNDSSMRLRASEMGETMAANLVLNSLLIFVTVFGFVVSPAITGWWLADLRKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIA7</accession>
    <name>A0AAD9DIA7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIA7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="413" mass="46374" checksum="E665AFE45D1DD6C9" modified="2024-05-29" version="1">MEYSSDDDSVVSSGDEMLNMVVPFSQDSATQKAAKGKKSESDDDSDNDDDGGSPSKKRRRVDENDDNKNDANDDVAAVNNDTIALANATNAFKIQFNDQKIGTTNKLYWNERRQKKNAALYPVRVVPREEVLGLCLKEWDAETERPVQYIQYPHKQIKRDLGLYDVVTVKSLTPYHGDGPADSWCSKRIQQYSKQLKRTLKGITEIDLITEEAFLNLVLKQSLKEEENEKERSLLDKAAPVESVASEKEDEKAENDSSSDDDDDADGSSGGRRSRLCRSNNVISEPLRVGDVIEYYKPQSVAGNPDALCEAEVKFINPKGDPILITSDVLTILPSDHQVKRVKRMHRGKLLDHNGRFRAINNYVLKKEGNPNAMKDIMAEATARTKATIQRAKDEIASRMDDGGFFPRDLIRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIW5</accession>
    <name>A0AAD9DIW5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">U6 snRNA phosphodiesterase 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">3'-5' RNA exonuclease USB1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_001772</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIW5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034477">
        <property type="term" value="P:U6 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1140.10">
        <property type="entry name" value="Cyclic phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027521">
        <property type="entry name" value="Usb1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13522">
        <property type="entry name" value="U6 SNRNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13522:SF3">
        <property type="entry name" value="U6 SNRNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09749">
        <property type="entry name" value="HVSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1747809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="426" mass="47020" checksum="75EFA5CA4BC38ED1" modified="2024-05-29" version="1">MDLLLAAGYDSSSSSSSSSQLSNKNNDSLREGNAQSALFGHTTNNSPCLGHNDDSSPSTADGNTAKKRSSCHSPRSPTAVKKQKSTKFITIASCDNDCQQSDQSFERSNPHWEGRWAGHIYLPFPNFDSCNTDDQNHDELNNETDANILADEDSDRGSDESSVSSIEDECLQASRSFLPAARALIHYWEALLNEVCVDIDDNVSGSVIVPHVSMSPKKTNPNSNQTVNKQDIQNNNTHLHISLSRPIYLPAPSVDSFLADITSSVSSIHSAARRHGHYSSHKGKIIHLRPHNATIFVNDNQTRSFLSIPVSDESSRWAKRLLLPSIDATMLRFGQKAYYDEGIMHVSIASVKGNMIPIILKKRRHKDLMHTTSGNESKISSIPLFQSPGCHQLADETRRCIPESIPIRLDRIQCDFGKAKNMALPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJS2</accession>
    <name>A0AAD9DJS2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Structural maintenance of chromosomes protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_000678</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJS2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215:SF14">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="627"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="64"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="317"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="558"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="634"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="650"/>
            <end position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1748739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="930" mass="104410" checksum="1BD9038CEA0F4D9E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2LZX5</accession>
    <name>A0A7S2LZX5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">rRNA-processing protein UTP23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_009447</name>
        <name evidence="9" type="ORF">SMAR0320_LOCUS17173</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in rRNA-processing and ribosome biogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UTP23/FCF1 family. UTP23 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="HBGZ01024208">
        <property type="protein sequence ID" value="CAD9619391.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S2LZX5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006984">
        <property type="entry name" value="Fcf1/UTP23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057776">
        <property type="entry name" value="UTP23_sensor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12416">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN UTP23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04900">
        <property type="entry name" value="Fcf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24779">
        <property type="entry name" value="UTP23_sensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="UTP23 sensor motif region" evidence="8">
        <location>
            <begin position="254"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="218"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="231"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF24779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CAD9619391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1739688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="275" mass="31446" checksum="AC90A7F02F358CE0" modified="2021-06-02" version="1">MRHGRAKASRRTLQFYRLNAPHLKSPYKILLDGTFLVASIRNKVPLWDRFSKTLQHEQFVCCVTRSTLNELELLSEQSAKIKPSGDSEENNSTFFDRARQYGLDECEIIENCNDVTNTNEKLMNKRAFRDFSEASKDIFCLATDGGNNRAAYFVATQDDGLSDALRAMPYVPLFRLGRAVLLLESPSSASRQFTGNLEQNKLKSAGGLMTSEERKIVDKVNKKDKKKRREMMKEEQQKMQKRSREEVGGCFNERKKKRAKGPNPLSCKSRKSKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2PUP9</accession>
    <name>A0A7S2PUP9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007817</name>
        <name evidence="1" type="ORF">SMAR0320_LOCUS16210</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="HBGZ01022643">
        <property type="protein sequence ID" value="CAD9617482.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S2PUP9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005740">
        <property type="term" value="C:mitochondrial envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.11.10">
        <property type="entry name" value="Cytochrome c oxidase, subunit Vb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036972">
        <property type="entry name" value="Cyt_c_oxidase_su5b_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CAD9617482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="170" mass="19065" checksum="DAF6730CF9470ACD" modified="2021-06-02" version="1">MFASTVRRAAITACRRQATATTTKTSCRTMANLPFNLDKILGGEPDNLIPLDKDRKSKPGYIPEFAPDDLRKEMEELGIDGVEDLDELEEKNMEGYNNLGLVPPEGAGTYASPILIPSRMDSRVVGYNDPTTHALFWFTIQNDNNTYYIKDLGLFFKMLHIPDEEAAAHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRH2</accession>
    <name>A0AAD8XRH2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_016868</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000066">
        <property type="protein sequence ID" value="KAK1732474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRH2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18572">
        <property type="entry name" value="ABC_6TM_TAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000854">
        <property type="entry name" value="Multidrug ABC transporter ATP-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF1">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041995310" evidence="9">
        <location>
            <begin position="24"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="197"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="529"/>
            <end position="783"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1732474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="804" mass="88782" checksum="219DCEF9A2E36060" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XS00</accession>
    <name>A0AAD8XS00_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SNF2 family helicase</fullName>
            <ecNumber evidence="7">3.6.4.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_016891</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000067">
        <property type="protein sequence ID" value="KAK1732410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047365">
        <property type="entry name" value="Tudor_AtPTM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF17">
        <property type="entry name" value="HELICASE-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21743">
        <property type="entry name" value="PTM_DIR17_Tudor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="1613"/>
            <end position="1963"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="157"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="173"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="232"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="246"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="299"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="354"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1732410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2252" mass="251535" checksum="CBBEFA8B1E96A702" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XS58</accession>
    <name>A0AAD8XS58_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_016815</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000065">
        <property type="protein sequence ID" value="KAK1732532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XS58"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1732532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="128" mass="14070" checksum="3414246B0BB14AA2" modified="2024-05-29" version="1">MTKLKDEHINETTPGMPAIIHPTVITSFVAVDDKSCMYAVNCNQAAPDESKMFKMQSSLAGIDNVGNGTLNDSKMALFLSIKPDKDDEKADKKNGVALYSTLPEQKIRIDKHSTVTRANDSLSWVPEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XS82</accession>
    <name>A0AAD8XS82_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">STIMATE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016854</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000066">
        <property type="protein sequence ID" value="KAK1732460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XS82"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022127">
        <property type="entry name" value="STIMATE/YPL162C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31735">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEIN YPL162C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31735:SF1">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEIN YPL162C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12400">
        <property type="entry name" value="STIMATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="281" mass="31632" checksum="1647BEF8C8693F94" modified="2024-05-29" version="1">MANDDYYAEAVEAEPVCQIYSKEDTFTSFVQGLLAAFALASLWVKRQQEKPRRKFLTWFLDVSKQAFGACYAHVLNMIISAIIAENAMGGDTLDDECAWYAINYVIDTTLGLVITIIFLDWLEKMAKYFNWTSLKNSGVYVGREGIMHWAMQMMAWIIILTLVKVIICVVMWLTSAPLAYIGAILFLPLQSNIRFELLFVMIFFPGVLNIIYFWITDSYLKAGGHQEGCHEGDELKELPPVNKDEETAAVTPYAEMGSTSADELAGNKDVATYGSTTRPFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTD2</accession>
    <name>A0AAD8XTD2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015782</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000048">
        <property type="protein sequence ID" value="KAK1733494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTD2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="111" mass="12145" checksum="3DF8BCC0FEAB7C2F" modified="2024-05-29" version="1">MTSSLRSQNSSTSRIPTKCKQLVLGDPWYVGVKDASSFGVGGIVVGEEKPVVPTVFRLEWPQTIRDNLVSEANPTGSITNSDLEFAGLLLLWLVMEAICPTLQYAHICHVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTH6</accession>
    <name>A0AAD8XTH6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000050">
        <property type="protein sequence ID" value="KAK1733412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTH6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="208" mass="23651" checksum="F563D50A5266CF4B" modified="2024-05-29" version="1">MASQQQQQRKQLLSYSAALESPRPSWNCVMDIDCQHQHADKRHDSPLPSPSLKKSLKKKQHRSVSFQSSSLLFCYGVPEDETQDWYTGEDEEIFKVEARKEVAVFQQLKMKGGFAGASGQSTSDPQHHRNLCIVGLEQQLISPEFSRKRAMTKKLVKYAVLLEQSKIGTGYGNSNKAERIAEAARRYSEWSAAQAQMFGDFQYIQSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTI6</accession>
    <name>A0AAD8XTI6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetyltransferase, GNAT family</fullName>
            <ecNumber evidence="2">2.3.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000053">
        <property type="protein sequence ID" value="KAK1733135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTI6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051531">
        <property type="entry name" value="N-acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792">
        <property type="entry name" value="GNAT FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00765)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="16"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="206" mass="23419" checksum="9B273C4C04D9141F" modified="2024-05-29" version="1">MITDKKRFEQLHTERLLLRRPTVEDANAIFSSYPTQKEVTKYLLFPPHESIHDTLNFIQWSDEQWKKKGGYNFILCSKADEGRVIGGVGLSLEGLDDEHESEEPKLPAGVARVSYYIVKEQWRKGYATEACKKMIELAIEVGITKLVAPVHPDNLASIRVLEKCGFQEDAMVCEMLVLPNLRKENLVGFGRSLSLSDPPPTLTWED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTJ9</accession>
    <name>A0AAD8XTJ9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_015657</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000046">
        <property type="protein sequence ID" value="KAK1733614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTJ9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="7">
        <location>
            <begin position="10"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="303"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1733614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="324" mass="36013" checksum="DDC7734ACD4FDA8D" modified="2024-05-29" version="1">MNQTDTTSCCASCGIAQVDDIKLKECTSCDLVRYCSDACLKEHESQHKEDCKKRVAELRDELLFKQPDSRHLGDCPICMLPLQLDPKKSGMMMCCSKVICKGCNFANQLDKEKYTMSSCCSKVICNGCNYANQVREAERRLEESCPFCREPIPSTKEECHKQAMKRVEANDPVAMCGEGFLQYQKGDYSSAFEYSKKAAELGYVGAHFMLAGLYRDGHGVEMDEKKSIHHTEVAAIGGHPDARCNLAYYEERNGDMKRAVRHLIIAATQGSDESIKSLMSTFKNGKVSKEVLAAALRAHQAAVDATKSPQRDVAEQKLSNITTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XU01</accession>
    <name>A0AAD8XU01_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015396</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XU01"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="101" mass="11130" checksum="0D0E629A2EDF255E" modified="2024-05-29" version="1">MRRIMNDKEAGRKKEVDEIAPRDSKKIRHRRPGTAGAPIAAPSMRLGAAISSSEVEHVLSPSFAEANLNDATDGGHRNPTNNLRLQRYNNNNNSTHLCKEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUJ2</accession>
    <name>A0AAD8XUJ2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_015157</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUJ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052423">
        <property type="entry name" value="EMIR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44094">
        <property type="entry name" value="DNAJ HEAT SHOCK N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44094:SF8">
        <property type="entry name" value="DNAJ HEAT SHOCK N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="65"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="463"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="575"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="463"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="584"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="606"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1734154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="677" mass="77152" checksum="9D6720E1151D27C4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUQ5</accession>
    <name>A0AAD8XUQ5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015485</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000044">
        <property type="protein sequence ID" value="KAK1733788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUQ5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="226" mass="25749" checksum="73C57CA0621D6B87" modified="2024-05-29" version="1">MFVDDDVYIEVYIRWRVEQAIAASIEAMFITLGQSDLPLRQDPISWDKLVGMIISHFNNILGVEINTRRMEVGPPPEFLARTVEQLDAFHEGRKAFTVQEMSTLVGHLSHIATTSRWLAHLLSHLYTSISAALKVNCAYEIDTNKAFRQAMKKVAEDESMTQNQRTFTQGYINRTVHESKWSHFLNSTAIEELRLTRLVLSSESISLRPPIAHLVSRDPTAEPLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV91</accession>
    <name>A0AAD8XV91_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015085</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000040">
        <property type="protein sequence ID" value="KAK1734318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV91"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="155" mass="17212" checksum="972E1452E74F6EEB" modified="2024-05-29" version="1">MTSSSPQTSAFSKHTQEQIQQPSTTSTTNDENPYGQMSLSARLLVFLLVPSATGLIGLFSSFLQSTRTPPEGQEPHTIDLDRDFMTPFLLGLAFVIVIGFQTGGFRVAGGMTAMERKFALSWPKAKRVRKVRRERVIVEDEDGDLDDGDDDKKDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVR2</accession>
    <name>A0AAD8XVR2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015087</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000040">
        <property type="protein sequence ID" value="KAK1734320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVR2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="279" mass="32485" checksum="FE0E8547D101B7F1" modified="2024-05-29" version="1">MQEVSQIHNNHCFKENRAAATEVSQINMLKSQESPTPPPPPFVVPRSPSSTPPLVPRSPSCLARYSHVDPAPKEQKHAAKKGFFSAFIPLKKRNSFKKDPKKKKVRFAPDEVEPYNWDYSCDQDVYYQKEQIMAMNKERFTDARKLRKLRNIKRPSKEAACDDIDLSKRAHNHNLDRLLKEAFDPERDIDEEVSICGIEHFVYPVLQLEMIRRKKQAQNEVLSFKKAKRQALRLAELSEEKTHWAREVAMEKGIRYCVNEEVAKSKPSCNWRRARRASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVR4</accession>
    <name>A0AAD8XVR4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014897</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVR4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="75" mass="7969" checksum="8230B75A1E193E8F" modified="2024-05-29" version="1">MLEKEEVARARQRDKITMLEEAVQKMQEAQAAVAAASSESISQCAANENMTMLAAESEDTTSASDTDTGTGKGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWT7</accession>
    <name>A0AAD8XWT7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014377</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWT7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="234"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="295"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="347" mass="38831" checksum="9BC7E3D6F8B68751" modified="2024-05-29" version="1">MSTLRTKHPFTGTAPEGLGGLTKLYLLQLQSNRITEIPDIIRLDDAEYGNSTFVTDCGVTQMTTVIPQEKTAVVKMGMNYGTFAVAFFAVFTILCCVVALSLYHFDKRKNSRKSFFNARVGEEGDTYALSKIGKGSVYSYFVTDKPIGWLVAFATLGIQIGILAFFVMASEASNLQDDKIDIEFTWKCPRDSDACKHKADWTKAGWVIFCLLMVAFLAKDMINGCKQWLGTNSAQECVISLVGCACVLLQYSPYITDIIVNSVIVLFIMEIDEYIFSAVDAMNEKWTEHAADTKVSEMEKEVARQRAQIASQQEKIDNQQKDLKRLREAVEKIQESQASAYECAECE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWZ2</accession>
    <name>A0AAD8XWZ2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA2/NAM7 helicase-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWZ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="1">
        <location>
            <begin position="61"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="196" mass="23070" checksum="A8048EB5636DFD24" modified="2024-05-29" version="1">MAHFLLARLYGKGQVVEKDEKRKFTIWKKRPFEVIPMLDTILDAGGERREECDDLGYHYDKRMVTKLVRNYRSHPRILQLPNEAFYNGDLIAAADITRSHRFVNWEHLLPWMQKPTACVVHRAASQKLNLNMNWCHVGFVIFISFDIAAKNAMRIIGRNMKHYAKNGCYETRYYSGSPKTHIWAIVQFVYCQCQLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XX36</accession>
    <name>A0AAD8XX36_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SDR family NAD(P)-dependent oxidoreductase</fullName>
            <ecNumber evidence="3">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013871</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XX36"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321">
        <property type="entry name" value="DEHYDROGENASES, SHORT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321:SF8">
        <property type="entry name" value="ESTRADIOL 17-BETA-DEHYDROGENASE 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="284" mass="29923" checksum="12AF4DEB77AE6D61" modified="2024-05-29" version="1">MSDQKFAAKTIIITGAGGNFGRAGCIHFAKLGARIAAMDNNDSALLETLREVNAAVDGEAPVIQTYICDVTDPKSVQETVEKISNDFGEINMLWNNAGYQGQIKPTLEYDPVDFARVMNINVTGMFIVLQSVAKEMASQKKADGDTTVSHPFSIVNTASVAALRGTPAMVAYSSSKAAILAMTVSSAKDLAPHGIRVNSISPALIGPGFMWTRQNELHAASGSPYFSSDPEQVAQAKVGGVPMKRLGSIDEVIKSVAYLLSDDSSYTTGTNLVVDGGLSAGLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XX53</accession>
    <name>A0AAD8XX53_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014106</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XX53"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="278" mass="31088" checksum="8E56EC3046F3F136" modified="2024-05-29" version="1">MKSELDVDTNNGDVVDEKQSKKNHPKFKLKSQNVCSPPPLPQGQGGEATNYVGNKKLFDIRQPTLTKTGEVPSRRIIMFDGFFFAKPQPPPVVADDLTPKETNGEKSSSAPKKIKERDVELFISEVETEKNTELDDKSTYRIAGRGQNEYGQFVLDGTYTPPTVFHKHNKAMVICNKTYGVGGTTKETRAAKGSKRKARSDDDSFDEDFDGEERADYTELIELSEDANLSVEELRKKYYGGGEDDEEEFDEDEDGGGKMSAVKKPRLDEESDDDECGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXC3</accession>
    <name>A0AAD8XXC3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA-directed RNA polymerases I and III subunit RPAC1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_014006</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXC3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07032">
        <property type="entry name" value="RNAP_I_II_AC40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00320">
        <property type="entry name" value="RNApol_arch_Rpo3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022842">
        <property type="entry name" value="RNAP_Rpo3/Rpb3/RPAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033901">
        <property type="entry name" value="RNAPI/III_AC40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050518">
        <property type="entry name" value="Rpo3/RPB3_RNA_Pol_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800:SF13">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01193">
        <property type="entry name" value="RNA_pol_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="Insert subdomain of RNA polymerase alpha subunit"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RpoA/D/Rpb3-type" evidence="3">
        <location>
            <begin position="60"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1735392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1110" mass="119992" checksum="569E49F429A6AFE1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2024-10-02" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXM6</accession>
    <name>A0AAD8XXM6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_013705</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1735542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="10" mass="1383" checksum="7DDDF206DEA40734" modified="2024-05-29" version="1">MWRLRCQEFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XY07</accession>
    <name>A0AAD8XY07_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DUF563 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_013990</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XY07"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049625">
        <property type="entry name" value="Glyco_transf_61_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007657">
        <property type="entry name" value="Glycosyltransferase_61"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961:SF150">
        <property type="entry name" value="GLYCOSYLTRANSFERASE FAMILY 61 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042287646" evidence="4">
        <location>
            <begin position="30"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 61 catalytic" evidence="5">
        <location>
            <begin position="427"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1735376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="731" mass="79860" checksum="8CFF95F8B60B84DF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYW1</accession>
    <name>A0AAD8XYW1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pentatricopeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_013034</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036063">
        <property type="entry name" value="Smr_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47932">
        <property type="entry name" value="ATPASE EXPRESSION PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47932:SF44">
        <property type="entry name" value="MIOREX COMPLEX COMPONENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="125"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1376"/>
            <end position="1407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="133"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1736434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1407" mass="156259" checksum="D33326A875861492" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYX0</accession>
    <name>A0AAD8XYX0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013151</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYX0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041966488" evidence="2">
        <location>
            <begin position="21"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="128" mass="14439" checksum="E5EFFE0D6DDF3BE1" modified="2024-05-29" version="1">MVNALLGLLLPFAFTPLVKFNCSKSIMGDNASKGVEKYTLYAFAITVWAINATTISATGGGFFGDILPDMEMSLKKMLLIIIQVLLQLYYAYWNFMTLFSRDRYDIIEQQQPIDDGLHSESHTEVEIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZF1</accession>
    <name>A0AAD8XZF1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DRBM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_012870</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZF1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
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        <property type="entry name" value="DSRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DRBM" evidence="3">
        <location>
            <begin position="257"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="120"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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            <begin position="287"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="387"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="430"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="575"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="664"/>
            <end position="726"/>
        </location>
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        <location>
            <begin position="764"/>
            <end position="790"/>
        </location>
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            <begin position="1024"/>
            <end position="1084"/>
        </location>
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    <feature type="compositionally biased region" description="Basic residues" evidence="2">
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            <begin position="147"/>
            <end position="162"/>
        </location>
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            <begin position="165"/>
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        </location>
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            <begin position="179"/>
            <end position="193"/>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
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    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
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            <end position="1046"/>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1051"/>
            <end position="1066"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1736270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1084" mass="116847" checksum="0EF7E3DA1C156AB1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZF8</accession>
    <name>A0AAD8XZF8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF2358 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013326</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZF8"/>
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        <property type="entry name" value="RIKEN CDNA 2310061I04 GENE"/>
        <property type="match status" value="1"/>
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    <dbReference type="PANTHER" id="PTHR31094:SF2">
        <property type="entry name" value="RIKEN CDNA 2310061I04 GENE"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF10184">
        <property type="entry name" value="DUF2358"/>
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    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
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        <location>
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            <begin position="78"/>
            <end position="112"/>
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        <location>
            <begin position="90"/>
            <end position="112"/>
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    </feature>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="484" mass="54145" checksum="0B6BBF1604C98035" modified="2024-05-29" version="1">MRRRIKSSAVTTSLALLSTAAIISSSSSSLSNNPLLAFTTAPPASDRIRRKLLARTILQASSSSSDDNQLSEFTKYTATATSKKEQEQQSSSSSNNDVTTNNNNNGIANPSSTLSMMVDQQREFEINLGRAVDTLKRDYPKLLTNDPSWNIYHSDLEVIDPTGVSLHGLSNYKRAFSFIHAVVYMFYCEEKSGLTFRSTYDWARKAIRISWNVELVPKMLMGGTRNTLHVDGISEYYLDRTSGLITEHKVSHLLINDQAVRPENGVFHALAEMSPVNPDGVPVFYGLDENEKKITWEDMTHVKFQTWNPFTNLISGKSPSSSSLFNNPNEQAMQLPENTNAINTDSQVPYDRDALQRKNDSRKKFGLPPITPDEFIKIEEEVRAMDAVNKKKATYLAEQLSQGRKKEEKDSFLNSIFGGVLKNGCESNFDCERPEVCCDVGFKKICCSSGLGIVDGIPLEKWEKARLRVPMENDDYGGNYGGNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZQ2</accession>
    <name>A0AAD8XZQ2_9STRA</name>
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        <submittedName>
            <fullName evidence="5">Nuclear pore complex protein NUP93</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_012359</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
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        <lineage>
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            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleoporin interacting component (NIC) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="protein sequence ID" value="KAK1736914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZQ2"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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    <dbReference type="GO" id="GO:0005643">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007231">
        <property type="entry name" value="Nucleoporin_int_Nup93/Nic96"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11225:SF4">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP93"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11225">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP93 NUCLEOPORIN NUP93 DEAD EYE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04097">
        <property type="entry name" value="Nic96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
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            <end position="108"/>
        </location>
    </feature>
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            <end position="175"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
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            <begin position="42"/>
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            <end position="94"/>
        </location>
    </feature>
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        </location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="159"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1736914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1178" mass="125112" checksum="BD085AEB868E6763" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0C7</accession>
    <name>A0AAD8Y0C7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012502</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1737057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0C7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="185" mass="18492" checksum="30AE426149532198" modified="2024-05-29" version="1">MPVKKPTISPTANPSSASPTAMPVEATVSPTTSHPTTTPSDSPSVTLLRTSMPVEATISPTTSSPTAPPSFASPTAMPVYATVSPTTASPSGSPSVTSRTAMPVETTASSIAASQSPTTEPTVTVNATTLSLTAPTSATTQMPTVPGIQTQANIANENSASTIFATLSGKKILLLIAVSGQVLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0Z8</accession>
    <name>A0AAD8Y0Z8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011932</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0Z8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="286"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="631" mass="72396" checksum="1C171AA1C98989D7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1V8</accession>
    <name>A0AAD8Y1V8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">P-loop NTPase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_011801</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
            <location evidence="1">Mitochondrion nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1V8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042645">
        <property type="term" value="C:mitochondrial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23075:SF0">
        <property type="entry name" value="ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23075">
        <property type="entry name" value="PUTATIVE ATP-ASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-1135">Mitochondrion nucleoid</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="565"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1737515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="923" mass="102411" checksum="2DFEFB8A080B2AA2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2A2</accession>
    <name>A0AAD8Y2A2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Chitin-binding type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_011401</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2A2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00035">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001879">
        <property type="entry name" value="GPCR_2_extracellular_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00187">
        <property type="entry name" value="Chitin_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50227">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041935466" description="Chitin-binding type-1 domain-containing protein" evidence="4">
        <location>
            <begin position="20"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="6">
        <location>
            <begin position="19"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 1" evidence="5">
        <location>
            <begin position="62"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="40"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1738107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="256" mass="27180" checksum="76D7231560B026E8" modified="2024-05-29" version="1">MKKQLISFLLLSNLAVSSAFRCGQNFGGKTCAEGGYEGYCCSSAGWCGTTEVYCGAGCQSGACGTTPPPPNFNYCGLLWDDAKLCLQSCYGGTDAECPPGQTCFANVAAYCPEVSPPNPGNRNYCGVSWEVANNQCSRSCYEGTDGECQTGQKCWADASDCSVVSPPSAMLLRGGAESDTQMMLAAETIVNEEQDQFIGQDMGVTGSGGPWYIWVIIGVAVLALIVCFIACRCHYKKKNKVAQEDDDKALDQPLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2M0</accession>
    <name>A0AAD8Y2M0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein CLEC16A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_010534</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901096">
        <property type="term" value="P:regulation of autophagosome maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039272">
        <property type="entry name" value="CLEC16A/TT9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019155">
        <property type="entry name" value="CLEC16A/TT9_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21481">
        <property type="entry name" value="PROTEIN CLEC16A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21481:SF0">
        <property type="entry name" value="PROTEIN CLEC16A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09758">
        <property type="entry name" value="FPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0072">Autophagy</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FPL" evidence="3">
        <location>
            <begin position="299"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="85"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="203"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="413"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="529"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="612"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="700"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="109"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="130"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="147"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="210"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="414"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="428"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="700"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="745"/>
            <end position="762"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1738504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1430" mass="155696" checksum="B18AAE055DE9FEEE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y307</accession>
    <name>A0AAD8Y307_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y307"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053337">
        <property type="entry name" value="AT-2_adhesin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37001">
        <property type="entry name" value="PHOSPHORYN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37001:SF5">
        <property type="entry name" value="RIIA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="151"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="361" mass="36712" checksum="B40B4D466CDDFA20" modified="2024-05-29" version="1">MGNPHFSDDGFQCFNPAKNFQLDWYDDSEITEDPRTAAYSNTLTLVGIGEYDNRGGNPVVVRLETGTGADYFVGFNRATGPNSLNDLGDDQVNIIQVEGGNGQSFSQSWLRALLSANQSYAISNFGGTGKTVTITVNSIDISTAPGTAVISISDGTSTPSPTSNPSSEPSLNPSVSGEPSSSPSLKPSVSSAPSSEPSSVPSMSNQPSKRSQPSSNPSVSGEPSSTPSSEPSLNPSVSGEPSSTPSLNPSVSSAPSTEPSSVPSMSSQPSSEPSLNPSVSGEPSSTPSLNPSVSSAPSSKPSNVPSMSSQPSSEPSFEPSSVPSTSNQPSSEPSLKPSVAGKAGKSKGPPSPVSYEASICI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3U2</accession>
    <name>A0AAD8Y3U2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HSF-type DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_010374</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3U2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="5">
        <location>
            <begin position="33"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1739058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="90" mass="10685" checksum="B9F1D93F9CE9077D" modified="2024-05-29" version="1">MCTRKNIPRRVTFESPPKSGMQEQQQFQQQQTFPFKLYNMLEYACDSEFSSCISWTADGSEFIIHDKDVMMDNLAPMFFNQTKFRSFAYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4A6</accession>
    <name>A0AAD8Y4A6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_010586</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4A6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021475">
        <property type="entry name" value="Pants/Emi1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11326">
        <property type="entry name" value="PANTS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1738556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="75" mass="8615" checksum="A185C94315DCA82C" modified="2024-05-29" version="1">MVQANDVVNVTLFFDEWTRCIGSGYQKDSLYRFGKFDACTPQWNDIKIALKAKTESDPIKATEMLKRHTTNKIGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4F3</accession>
    <name>A0AAD8Y4F3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">COP9 signalosome complex subunit 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_009916</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CSN7/EIF3M family. CSN7 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4F3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045237">
        <property type="entry name" value="COPS7/eIF3m"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350:SF5">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="PCI" evidence="4">
        <location>
            <begin position="151"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="306"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1739373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="353" mass="38312" checksum="ED50117297678F30" modified="2024-05-29" version="1" fragment="single">MTTAPLSSSSSTAAGSLLIDEFFSSKSLSPALLHSLLQRLLSHPRIHNGFVDILQLPSVQSALENMDEAKRDSLIATVKLFAFGTIQEYHELKEKNGDAVWTLTDAQLDKLRMLSVVSVARRGQIKSSEKTDVDMIPSDHTAAANNNASLSIPYAHLAAELQITPVGTPFNDKDHMRQLEDVLIQCVYSNIIAGKLDQASKAFVVESHVALQDQQQLSSSSSLGMKKENGANKSTTTSITVHGSLLSRDIDTTTAESTNTEVKRMISTLGQFLSSSNKLLSSLEDISNVSASLRKEDEKRWRNVEKKLSEEGSGSSSRFRAPGGDCDVIFEGGGGGDPMEVVDMSGRRKVKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4J1</accession>
    <name>A0AAD8Y4J1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010369</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4J1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="259"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="378" mass="43505" checksum="E822FD7C062E2589" modified="2024-05-29" version="1">MSPTATAATPLASKSQSDWWREAAQSFSPSKITSGTNDNDDNNYGSIAPPSYVTSPTRHNPFNEGMTANNLSLQDHTATSTRDSYDDDDIFGNDTNNILQPREGTLSDISNDSSSDSDSDDDYSSYASDDSDHSLERPHRTVGLIFFDTLRLVAISANVRFFNTEMVPVLMAWKTMDILNKCLRIFMGSSSILLITLEFPEFFPFLQHNPLSQPTPPLYVSNWIPRGIFYLFLALVMFEQQVVVAFIDVKRHASTSSRFFDGIFMVISAAIMILVGMTYILLGMFCVQKIMERVRREEMERWDEYWEKLKKLEEEEDLEEEREWLLENGGELGQGDGKSIRSGAAAIGFKERWRKWRKRFKRRYRRGRGWWRSIDFKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4S4</accession>
    <name>A0AAD8Y4S4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_010358</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4S4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007378">
        <property type="entry name" value="Tic22-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33926">
        <property type="entry name" value="PROTEIN TIC 22, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33926:SF4">
        <property type="entry name" value="PROTEIN TIC 22, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1739042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="347" mass="37087" checksum="EA1B60F23443CB8F" modified="2024-05-29" version="1">MPSMVKYSTFYAAALAIAGTTEGFAPISSSRKAGTATTLPSPEAILQQHQRALAPSANLQIQSHDTSCALQQHTTTTLQMSSNNDNEGPAPITAIFISLVLLFFVVSAFAPLLDFASIQPSNQDLNLGDAVVTRQDDTNKLKNYQSKFDALSSTRIQQKLANLPVFYIAQDGGMQENIYFSYSEATKAASGEGSVVKVTTLDQIMYPLILKREGMFKPTAATPIEVKNAIASSSSTTYKLVPSAAAVTDAKDTGTTLKEGDIPLFSIARLAFAGSGGQPQVPLFLERADGVTSYTRLGKSDEAVVRTTSLLDVLDSMERGTRPAVGQLEFYGNAEDVLKADEMSSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5H6</accession>
    <name>A0AAD8Y5H6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">VASt domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_010023</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5H6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031968">
        <property type="entry name" value="VASt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16016">
        <property type="entry name" value="VASt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51778">
        <property type="entry name" value="VAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VASt" evidence="4">
        <location>
            <begin position="971"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="69"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="120"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="330"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="639"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="84"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="182"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="336"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="642"/>
            <end position="659"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1739480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1155" mass="130160" checksum="791B3ED2A971C702" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5W2</accession>
    <name>A0AAD8Y5W2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7495 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009748</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5W2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055918">
        <property type="entry name" value="DUF7495"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24325">
        <property type="entry name" value="DUF7495"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7495" evidence="1">
        <location>
            <begin position="18"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7495" evidence="1">
        <location>
            <begin position="158"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7495" evidence="1">
        <location>
            <begin position="400"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="589" mass="65037" checksum="C1CA3F49EDA8C992" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5Y5</accession>
    <name>A0AAD8Y5Y5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADH:ubiquinone reductase (non-electrogenic)</fullName>
            <ecNumber evidence="2">1.6.5.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_009368</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a quinone + NADH + H(+) = a quinol + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:46160"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.6.5.9"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a ubiquinone + NADH + H(+) = a ubiquinol + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:23152"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.5.9" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5Y5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050136">
        <property type="term" value="F:NADH dehydrogenase (quinone) (non-electrogenic) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054585">
        <property type="entry name" value="NDH2-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706:SF47">
        <property type="entry name" value="EXTERNAL NADH-UBIQUINONE OXIDOREDUCTASE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22366">
        <property type="entry name" value="NDH2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042100614" description="NADH:ubiquinone reductase (non-electrogenic)" evidence="10">
        <location>
            <begin position="22"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="11">
        <location>
            <begin position="138"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="External alternative NADH-ubiquinone oxidoreductase-like C-terminal" evidence="12">
        <location>
            <begin position="541"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF22366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1739609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="620" mass="67694" checksum="C169CB3401057168" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6Q4</accession>
    <name>A0AAD8Y6Q4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Transmembrane protein 43 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_009143</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TMEM43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6Q4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005637">
        <property type="term" value="C:nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071763">
        <property type="term" value="P:nuclear membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012430">
        <property type="entry name" value="TMEM43_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13416">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13416:SF2">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07787">
        <property type="entry name" value="TMEM43"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="418"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="448"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="207"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="218"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1740193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="516" mass="57392" checksum="0E71155B00F8FDF9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7E3</accession>
    <name>A0AAD8Y7E3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009309</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7E3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38909">
        <property type="entry name" value="G PROTEIN GAMMA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38909:SF1">
        <property type="entry name" value="G PROTEIN GAMMA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="207"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="179"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="291" mass="31372" checksum="DA7FF37D6AA52692" modified="2024-05-29" version="1">MVSLLCFKNKKKKKNNQKQPQNDGRNQKSSQEEKGLLSPTSTAGMKTLSSNASSKDTGYSTALSGIGSHSNTKNNYHDDSSIPTIDSDYNQHNSNFSLSDAGGTIGSRSLANFSHATSAFGGDTITNTISGGGGDSVERRLYNDVYMSQHHSVGYHENGSQQQQRQQQQLSHLIQPPTSRGNDGYGRYNNGSGTAPQETFTIDAPKGKLGVVIDTPYQSNTGTTMPIVHAVKDSSPIADRIQVGDKLIAVDEEDVTSMSAIQVSKLLARKSEQSVRKLTIVRTVRGRGGIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8H0</accession>
    <name>A0AAD8Y8H0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_007915</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8H0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16448">
        <property type="entry name" value="RING-H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051826">
        <property type="entry name" value="E3_ubiquitin-ligase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765:SF434">
        <property type="entry name" value="GB|AAD18119.1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765">
        <property type="entry name" value="RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="174"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="85"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1741437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="268" mass="29719" checksum="EFD1AD73BD4A5FCF" modified="2024-05-29" version="1">MVGSFLSISMWSAISAFIGTMILIYSAIVVLRLRGVQIWGAPPPSPASVVAALSDEDKEKIEKLRSSAIIRHLNKYTTTLNEGNMTTLTSTTEEESTTTCISTENSHSDQGDEEQPQVDIEEGTISDDKTEYSHICVPLPGQQSCVSNTNETDNTSETSSLNDIPDTRNVPNLCVICHEEYETSDKVCWASSSDCTHVFHEECIVRWLTSLGWMKLKEQKEPQNMIDEDRCLNYDLECPMCRGQFICKDHLIKNTPVVVAAGTGDESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8S0</accession>
    <name>A0AAD8Y8S0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008304</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8S0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="27" mass="2925" checksum="284AA95BB3B728FC" modified="2024-05-29" version="1">MLQARRTETTSKQLSSGCFESGHGPIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9Q4</accession>
    <name>A0AAD8Y9Q4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006939</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9Q4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026913">
        <property type="entry name" value="METTL24"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32026">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32026:SF10">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 24-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13383">
        <property type="entry name" value="Methyltransf_22"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="1">
        <location>
            <begin position="30"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase" evidence="1">
        <location>
            <begin position="152"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="287" mass="32214" checksum="48C1CE76B6F190BF" modified="2024-05-29" version="1">MSNNNADTHEVVAYAPLTSCDEEVLDSLDKRFNQKRSERQSAMKSSMGEELSFDIYEPEATCLSEERFGTDIRYHAFGDGPKFICGVDFIAHQTAHEGKKCLVYSVGSNNDVSFEKAVHTFMDGEVHTFDPTLSSPFDGVEGVHEGKKWSGKSFETIIRELGHENRTIDVLKIDCEGCEWDTMSPLFELMSSGRVKINQVLIELHLRSGPQQLKDFFGNADKAKMRVFHKERNGWGCGGKLCVEYALASETFLREANRDSICPYQRVKGDDADADWKAAGNTTDRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAA3</accession>
    <name>A0AAD8YAA3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Heat shock factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_006962</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAA3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0346">Stress response</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1742397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="253" mass="27039" checksum="68CA8C8B4174BA19" modified="2024-05-29" version="1">MVTQMAQTIRQMNEGTAAAVTTTPVPTYEPVQKKRKLDVDNVLSMPVSQSLGHSLDGCDNEYAGVELLDPTVSDADLLVEDYSVFQSSREPQRCESADLVEDMFDFVQDDGKFDTANSLAPENVNSSACLNRSVSYNGSDESVGQDQQHKVDPKVSEKLNNALSMLPKTLQGAFVERMVDTIANPDSYQKHVDAVSVLATAAAIEAKNHEQQPASTNANAVPIAAAALGAFLTKYSNAMDGSAGAGGQVHVKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YB50</accession>
    <name>A0AAD8YB50_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-histidine N-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.85</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_007068</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the methyltransferase superfamily. METTL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.85" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YB50"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018064">
        <property type="term" value="F:protein-L-histidine N-tele-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF39">
        <property type="entry name" value="HISTIDINE PROTEIN METHYLTRANSFERASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 11" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1742503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="346" mass="37997" checksum="3B69B05160E35DE8" modified="2024-05-29" version="1">MFKFDFTSSTDGADHADNSEKEKKAEADRMIAKIEERSMTTAQSCKLLNASASTSDKVKSCVHERVEMHSSSIDGLHYILPQQTALSEKNTDLIPGVYEGGLKVWECSLDLCRFLAHVMDGTISTEADFRHVTEAVRRSIENGGSAFELGCGHGLPACLILRESVRRYTNSVVVFSDFNDFVLRDVTIPNALLNVCGLYQQQGNDSVDDSASQALLKQSIYAGGDWMGLSHKLSNDEVVLPATERLVDEQFDVLLASETTYTTESCQDTAYLMLKHLKVDIGVGLVATKRFYFGVGGGADAFSQAADKVSESSQSHGLRLVVRTIQSYDTGNANIRDLLEVRLVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDD0</accession>
    <name>A0AAD8YDD0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">H15 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005704</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDD0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005818">
        <property type="entry name" value="Histone_H1/H5_H15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00538">
        <property type="entry name" value="Linker_histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00526">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51504">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="H15" evidence="2">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="185" mass="21036" checksum="EC5D5B28F21A517E" modified="2024-05-29" version="1">MPYRSAILAAIESLKDHETGSPISSIRRHILDDTDDNNSDDPSWNEVHFQKTLKTLVEKGDLLQINGINFKFSNQYLQRRVEALRARAESIEEQTHKTAVEHHHSREIPAKEAPKKKTVHAKMKINEGKIITVVNPEVKHDDDMDTTPTEEIDVERGGIRAAVGKNKKHVKIKPRRVAGTTKNIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDE1</accession>
    <name>A0AAD8YDE1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_004962</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDE1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052420">
        <property type="entry name" value="Espin/Espin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153">
        <property type="entry name" value="ESPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153:SF8">
        <property type="entry name" value="FORKED, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1744429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="214" mass="23939" checksum="C12B4D21F063C26D" modified="2024-05-29" version="1">MSLSINKFMNYVAIVLDLIHRQEWAALEKVATTKHKLFKVISEHIKKCDEFNGMTLLHAAVKYNPPMHILDAMIDAHSDALMGQDCVGRTPLHVACGTGADAEIIRLLVEAYPQACDLQDEDGRLPLHLACDIECVLFEGDQTERAPPTIDVVRALLSGSWRSVLVEDEDEMSPIEYAIVSDANIKVVKLLQKTSMTLRRKEAQANCKKYSKGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEZ0</accession>
    <name>A0AAD8YEZ0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_004572</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEZ0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1745281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="382" mass="42964" checksum="CC5050C298C79603" modified="2024-05-29" version="1">MPPLETEYALMPAIMRLEQRDCRLSSIDLRGKGKRRSDGDDALIKEAAPSPLIEKFALALKYYDRPQLKSLALHNHFLDPIELQLMFDALRFIPTLESLVLFHHDLGDSGVQLLMQALLGSKEETTPLKELYLSHCGITCKGAAEIADALHQSSSTANCTSNSNCKLSCLQVLSLGSNQIKPEGALCLAKAFALYPPLHRIVLHGNKDIPGEMKDEFKKHFIFYQAMIPTGWQRNTPRSQRTTPASTITNPSTIAMAVLSPLILPHVQRRWQKDRVLIRPYDELRRQLKHEMYKKGSTFVDSESQLKLMPDILAYIAREGMCLKQTSLNSHFDYLTGGRVKLCHSIGCASCPACACTGLNDVYELLHRMPHLLCLLRNRLQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFB7</accession>
    <name>A0AAD8YFB7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004104</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFB7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="109" mass="11864" checksum="BE3DD18EBACF6436" modified="2024-05-29" version="1">MGAASNNDNEEHEFGEDQSTNNDATSTNHDDASAQQPMTCSTKSSPADSSVVFSPELLGMYYARLFPYQMLYSWLSYDPATINPNNNNNNTTKNGTSNNTPPFPDASSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFE5</accession>
    <name>A0AAD8YFE5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GPI inositol-deacylase</fullName>
            <ecNumber evidence="1">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_003448</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GPI inositol-deacylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFE5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012908">
        <property type="entry name" value="PGAP1-ab_dom-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47909">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47909:SF2">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07819">
        <property type="entry name" value="PGAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SCP" evidence="3">
        <location>
            <begin position="253"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="50"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="428"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="443"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU365011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1745524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="883" mass="96527" checksum="B86C06550F79E76F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFL7</accession>
    <name>A0AAD8YFL7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RxLR effector protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFL7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041967469" description="RxLR effector protein" evidence="1">
        <location>
            <begin position="36"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="384" mass="42607" checksum="25ADA7AB325B04E7" modified="2024-05-29" version="1">MKMQQLRRPMMAVAAAATTLLLLCCSSSSLSLVDGFVPPTHTTTRLAHHRSGGFQPTHQLHSSAAADDDDVSETAALTTVDPKAKAEIRNILNHLSTQTLESLLSPSDAKLIYEELFFSSSDDDDEQSSIFNDETYQQYVKYWDKLGRKLREETRTPADLLGTDITNRILSFIRGDGDGSSSSSGSYDAQTVKTFLESDAINSLFTQLLYDAIFEFTTSIDIIGNAISKLPLLGPVRNQVLKESKRNMDRTLGPLLRQFLSGYTRVAIRQAVDFVVSKENASNFASANAKLVGYLLKERSVSAWIPEDKVLAEWRQDVWDYLVGLERGSDNQKIINQSIDWVYDLVGDKCIDDAGVNVGSIIDSSPTLEKNAALFWKRCQDNAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YG20</accession>
    <name>A0AAD8YG20_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromatin target of PRMT1 protein C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_003366</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YG20"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025715">
        <property type="entry name" value="FoP_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13865">
        <property type="entry name" value="FoP_duplication"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01218">
        <property type="entry name" value="FoP_duplication"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Chromatin target of PRMT1 protein C-terminal" evidence="3">
        <location>
            <begin position="60"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="148"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="7"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="70"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="148"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="165"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1745442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="185" mass="18232" checksum="B8D0ADDFA6A448BA" modified="2024-05-29" version="1">MARTNQKGGGGRGGGNNRRSSGGGSGGRGGGGGGGGGGRRNSGGGGNNSPAKRSNQGQAGGSRKRYSDGGNKGRGGGGGRGGGGGRRSGGGRGGGGGRGRGRGRSSDRGGEKQKPATAEELDAAMDNYWMKSGNKELAEKKLNDDMDDYWAKKEGDNDGEAAKEGEEEEKPAAEEETAAAVAAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGY6</accession>
    <name>A0AAD8YGY6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">SOS response-associated peptidase (SRAP)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_003712</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SOS response-associated peptidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGY6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106300">
        <property type="term" value="P:protein-DNA covalent cross-linking repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1680.10">
        <property type="entry name" value="SOS response associated peptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003738">
        <property type="entry name" value="SRAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036590">
        <property type="entry name" value="SRAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13604:SF0">
        <property type="entry name" value="ABASIC SITE PROCESSING PROTEIN HMCES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13604">
        <property type="entry name" value="DC12-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02586">
        <property type="entry name" value="SRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143081">
        <property type="entry name" value="BB1717-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0190">Covalent protein-DNA linkage</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="24"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1745788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="381" mass="42208" checksum="505A8095FFBFAEF7" modified="2024-05-29" version="1">MCGRAAYSTASFSSAASALRCSDSSPPSAAAASSTKKDELASSSASSSDTTINNVNMSPGTSAKIFIYNHTSNSVCSTSMVWGLLPNNGTPQSPHLLPSDDKFTPSPHYIMFNARSETVDAKKSFHSLLRDGQSCIFAVDGYYEWTKSLSPIDKKKQPYFVKSSSSDTLLLAGLWSRVKTGRRNNNNQEETISTFTILTTEAHPTLAWLHPRQPCIIGSTVAREWLQSPSRALVDKIRPLSSGQQQQQHDIKNERTDPWECYPVTKKMNDAKYHGDDCTVAVKSKGRKLESYFTTSPSPCKRKKIEVKEDYSESTSQQDVEEKNVTTKCSQKDESNALLLTETINNEWSCHVCTFLHTKSKSQFLACEMCGSQRECTQDIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHP1</accession>
    <name>A0AAD8YHP1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cilia- and flagella-associated protein 77</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003653</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHP1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020339">
        <property type="entry name" value="C20orf85-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029147">
        <property type="entry name" value="CFAP77"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28617">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28617:SF1">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14825">
        <property type="entry name" value="CFAP77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14945">
        <property type="entry name" value="LLC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0282">Flagellum</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="316" mass="36326" checksum="EF74B4CB0CEB40FA" modified="2024-05-29" version="1">MDTSGKNKRVTMIKSVVGKVKSAQYALPDIVYGIESKMDKEGAGKVIESWAVAEPSPLPISMQSFPATNRQALKHGCLTSKAQREYGKQHPVMKQSPKHSNMGHQSKENAEVKSNSNDVITSIYQRNLNQQPHHVFGIQTKKNNASMDELLRCIPSELEEETDYPDLSGKKRKGRIPPAKATKASQSVAECRPMTRTKAVDEFKMKKFLNVQSKVKCYIHQCDQTEYNYVAEAFNWEQRVKGENDAAREWNKNWGSLFLSNQPTSYKERIYDLKRKMTEEKLPVQSNYQMSYTKTNPYRKFGEKDHRRKRCDMDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHV5</accession>
    <name>A0AAD8YHV5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHV5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="211" mass="23390" checksum="89AB5C07FBCE0254" modified="2024-05-29" version="1">MTLTSPSRQGGGAIATLKCPSCNSEHHAKTDIFGNRYKHCSDEGSDFGVLELFGAKAKCAICLETCEDIVGLPCGHCLCKSDYKRMGGIVRAFNEDEHQHRGECDDDVIVTVKRAGKKEVNGTYKKDCNRYTRSARYDGKDVEYSIEKRVVNGKKMWVLCCRSEDQGKEDPVDFYRATVNETCEYPSSVKWVSTLIGSGPAPRSEVSYFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHY5</accession>
    <name>A0AAD8YHY5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">histidinol-phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Histidinol-phosphate phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_002965</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-histidinol phosphate + H2O = L-histidinol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14465"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="3.1.3.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 8/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.15" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHY5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004401">
        <property type="term" value="F:histidinol-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01641">
        <property type="entry name" value="Bacterial_IMPase_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.540.10:FF:000030">
        <property type="entry name" value="Inositol monophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011809">
        <property type="entry name" value="His_9_proposed"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051090">
        <property type="entry name" value="Inositol_monoP_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02067">
        <property type="entry name" value="his_9_HisN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200:SF6">
        <property type="entry name" value="3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200">
        <property type="entry name" value="PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="12">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR600760-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1746358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="304" mass="33267" checksum="1C5CDBEC5484F991" modified="2024-05-29" version="1">MTTITNNELVSFANELADAARTVILPFWRQPIEVESKMEHDRPIAESPVTAADRKAEEVMRKLIEERYPSHGIYGEEFGQVRTDAEYVWVLDPIDGTKSFITGKPLFGTLIACLKDGVPIVGVIDQCVLKERWVGAVGQGTTLNGKPVSTSGCATLKESMMYATTPHMFHKGEEADKFEKMCDTVLRPLYGADCYAYAIVASGFGADIVVEADLGLYDYCALVPVVEGAGGKMTDWYGRRLTLENHERSKGRVVACANEGLHKEAIAILGKTWRNSFIPSITKDGLLYLAVGAILGAALSRPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIN1</accession>
    <name>A0AAD8YIN1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">NADH dehydrogenase [ubiquinone] flavoprotein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_002322</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I 51 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIN1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1440.230:FF:000001">
        <property type="entry name" value="Mitochondrial NADH dehydrogenase flavoprotein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.600:FF:000001">
        <property type="entry name" value="NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11540:FF:000001">
        <property type="entry name" value="NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11540">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 51kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.230">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050837">
        <property type="entry name" value="ComplexI_51kDa_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001949">
        <property type="entry name" value="NADH-UbQ_OxRdtase_51kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011538">
        <property type="entry name" value="Nuo51_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037225">
        <property type="entry name" value="Nuo51_FMN-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019575">
        <property type="entry name" value="Nuop51_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037207">
        <property type="entry name" value="Nuop51_4Fe4S-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054765">
        <property type="entry name" value="SLBB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11780:SF10">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11780">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE FLAVOPROTEIN 1 NDUFV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01512">
        <property type="entry name" value="Complex1_51K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10589">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22461">
        <property type="entry name" value="SLBB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00928">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142019">
        <property type="entry name" value="Nqo1 FMN-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142984">
        <property type="entry name" value="Nqo1 middle domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140490">
        <property type="entry name" value="Nqo1C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00644">
        <property type="entry name" value="COMPLEX1_51K_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00645">
        <property type="entry name" value="COMPLEX1_51K_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding" evidence="13">
        <location>
            <begin position="308"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="675"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="675"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="718"/>
            <end position="736"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1746978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="736" mass="82389" checksum="F828B74193E74B40" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIY4</accession>
    <name>A0AAD8YIY4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF1275 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001407</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIY4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010699">
        <property type="entry name" value="DUF1275"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37314">
        <property type="entry name" value="SLR0142 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37314:SF4">
        <property type="entry name" value="UPF0700 TRANSMEMBRANE PROTEIN YOAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06912">
        <property type="entry name" value="DUF1275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042213532" description="DUF1275 domain protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="315" mass="34816" checksum="F6689D47F68E3370" modified="2024-05-29" version="1">MKSALPYLFLASAAVAFSPASLPPQRSISTNHVRVSPGFKQVKRSNNNVNSISKLPSTTTALSAAATTSARQFNAKKRVATFMAFMTGWADFLLFTKYKFFATMMTGNSMWMMSAIVDARFRDVAFYASVIASYIFGVGLFRRAELSYKEKALTGLFAPVVTTCFLLSDYLTMLNPACRWIPALMLAFSWGIINSVGSEVTGTLIFVVTGAMTRFSNMIVDRISRTAGRKKIPKEGLMMTLSVIGGFWLGAGWSVWLNKNAPQLTKYGVFSIIGVIYGSLFLYLDREQLGAWWSRKNGKLCEIDGDEVNCAEPEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJA2</accession>
    <name>A0AAD8YJA2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Metalloendopeptidase</fullName>
            <ecNumber evidence="7">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_003176</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6 7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6 7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJA2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04280">
        <property type="entry name" value="ZnMc_astacin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034035">
        <property type="entry name" value="Astacin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF780">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6 7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4 6 7" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041773027" description="Metalloendopeptidase" evidence="7">
        <location>
            <begin position="21"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12A" evidence="9">
        <location>
            <begin position="101"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="26"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="439"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="535"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="801"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="444"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="538"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="562"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="604"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="617"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="638"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="662"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="687"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="706"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1746569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="932" mass="101359" checksum="9325094C5741A5D2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJP2</accession>
    <name>A0AAD8YJP2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mitochondrial splicing suppressor 51-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003227</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJP2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046824">
        <property type="entry name" value="Mss51-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47570">
        <property type="entry name" value="ZINC ION BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47570:SF1">
        <property type="entry name" value="ZINC ION BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20179">
        <property type="entry name" value="MSS51_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mitochondrial splicing suppressor 51-like C-terminal" evidence="1">
        <location>
            <begin position="404"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="603" mass="67337" checksum="B8B93AE1B4989CA6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKH8</accession>
    <name>A0AAD8YKH8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002109</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKH8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="197" mass="20586" checksum="B2D99C4FEB82FE73" modified="2024-05-29" version="1">MGGMGANGSVSMSVLADRTFGTTCLSTFLTGVMMFIFMAWGYPVINYMPLSAISGISIAIACSFIQWRSLAAVFTTCLPERRLGVFLFDACLKLVGKKEEKEETVEGAIAASVSNTIAKLMQEGVLPQPSPTSEAAKKGSKAGVAPIADGEQADDVSVGSGYLDSIASSWSDGSSGGEGEGIYYVHSDDDLDNQSPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YML4</accession>
    <name>A0AAD8YML4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YML4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="112" mass="12235" checksum="A79D9EE656CFBFBE" modified="2024-05-29" version="1">MLREAMEKIQESQEEAATATIAFNFQSAEYEDNLMHNSMTTHAAESEDNGSDTDAGKEVTTQLMTEGRERTPERSDCAREGTPSTRTGVAASGSETLNVRVTQKRSFNGVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMT1</accession>
    <name>A0AAD8YMT1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">V-type proton ATPase subunit a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_000293</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the V-ATPase 116 kDa subunit family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the replication factor A protein 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMT1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016471">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051117">
        <property type="term" value="F:ATPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04478">
        <property type="entry name" value="RPA2_DBD_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014892">
        <property type="entry name" value="RPA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002490">
        <property type="entry name" value="V-ATPase_116kDa_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11629:SF63">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11629">
        <property type="entry name" value="VACUOLAR PROTON ATPASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08784">
        <property type="entry name" value="RPA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01496">
        <property type="entry name" value="V_ATPase_I"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="343"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="388"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="472"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="505"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="629"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="700"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="domain" description="Replication protein A C-terminal" evidence="10">
        <location>
            <begin position="887"/>
            <end position="985"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1748354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="991" mass="110662" checksum="A44ADF3FC423660E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMY3</accession>
    <name>A0AAD8YMY3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphatidylinositol 4-kinase</fullName>
            <ecNumber evidence="5">2.7.1.67</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_000174</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.67" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004430">
        <property type="term" value="F:1-phosphatidylinositol 4-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05168">
        <property type="entry name" value="PI4Kc_III_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015433">
        <property type="entry name" value="PI3/4_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057754">
        <property type="entry name" value="PI4-kinase_beta/PIK1_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048:SF22">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="4">
        <location>
            <begin position="1424"/>
            <end position="1729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="188"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="911"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="983"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1026"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1170"/>
            <end position="1203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1356"/>
            <end position="1377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="109"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="188"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="987"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1038"/>
            <end position="1055"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1748235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1745" mass="191936" checksum="3DA8756E4D50293C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4P8</accession>
    <name>A0AAD9D4P8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Triacylglycerol lipase</fullName>
            <ecNumber evidence="9">3.1.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_016378</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PLPL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.3" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4P8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021771">
        <property type="entry name" value="Triacylglycerol_lipase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF66">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE PTL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11815">
        <property type="entry name" value="DUF3336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="8">
        <location>
            <begin position="466"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="419"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="5">
        <location>
            <begin position="497"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1732840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="619" mass="71380" checksum="74729BBDC4EEE702" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4V2</accession>
    <name>A0AAD9D4V2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase</fullName>
            <ecNumber evidence="3 12">2.4.1.131</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_016217</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes, on the cytoplasmic face of the endoplasmic reticulum, the addition of the fourth and fifth mannose residues to the dolichol-linked oligosaccharide chain, to produce Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>an alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP-alpha-D-mannose = an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:29523"/>
            <dbReference type="Rhea" id="RHEA-COMP:19515"/>
            <dbReference type="Rhea" id="RHEA-COMP:19516"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:132511"/>
            <dbReference type="ChEBI" id="CHEBI:132515"/>
            <dbReference type="EC" id="2.4.1.131"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11 12">
            <dbReference type="Rhea" id="RHEA:29524"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.131" evidence="3 12"/>
    <dbReference type="EMBL" id="JATAAI010000054">
        <property type="protein sequence ID" value="KAK1733079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4V2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004377">
        <property type="term" value="F:GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03806">
        <property type="entry name" value="GT4_ALG11-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000256">
        <property type="entry name" value="GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038013">
        <property type="entry name" value="ALG11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031814">
        <property type="entry name" value="ALG11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45919">
        <property type="entry name" value="GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45919:SF1">
        <property type="entry name" value="GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15924">
        <property type="entry name" value="ALG11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 12 15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="279"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="ALG11 mannosyltransferase N-terminal" evidence="14">
        <location>
            <begin position="77"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="13">
        <location>
            <begin position="331"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF15924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1733079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="543" mass="60975" checksum="AAAA9BEF6EB78DF4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D550</accession>
    <name>A0AAD9D550_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">EngB-like GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_015977</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000051">
        <property type="protein sequence ID" value="KAK1733260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D550"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01876">
        <property type="entry name" value="YihA_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030393">
        <property type="entry name" value="G_ENGB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11649:SF13">
        <property type="entry name" value="ENGB-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11649">
        <property type="entry name" value="MSS1/TRME-RELATED GTP-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51706">
        <property type="entry name" value="G_ENGB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EngB-type G" evidence="6">
        <location>
            <begin position="233"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="93"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="418"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="133"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="196"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1733260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="530" mass="58528" checksum="19F4EA03546B0212" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D643</accession>
    <name>A0AAD9D643_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000040">
        <property type="protein sequence ID" value="KAK1734263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D643"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="595" mass="67992" checksum="14040A842A1D0D4D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6Q7</accession>
    <name>A0AAD9D6Q7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Purple acid phosphatase</fullName>
            <ecNumber evidence="5">3.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_012826</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.-.-.-" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6Q7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00839">
        <property type="entry name" value="MPP_PAPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041792">
        <property type="entry name" value="MPP_PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039331">
        <property type="entry name" value="PAPs-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025733">
        <property type="entry name" value="PAPs_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22953">
        <property type="entry name" value="ACID PHOSPHATASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22953:SF153">
        <property type="entry name" value="PURPLE ACID PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14008">
        <property type="entry name" value="Metallophos_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="3">
        <location>
            <begin position="140"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="Purple acid phosphatase C-terminal" evidence="4">
        <location>
            <begin position="380"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1736226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="473" mass="54281" checksum="25F042377642CBFD" modified="2024-05-29" version="1">MTISFSISSACVGKKGPGKKSIGAVRLIGEGEEDDFLVIGDGNNTKSYDAMSPRRGIKRYYSDLYYHIEIDDLRPDKDYSYECLLFNKDDMSSQQYLREDRTTVDISGDHTSVIARSDISTFTTPPAPGQWHSSGRTIIFAVLGDLAAKEHSKKTMRHLDRHSESVDVILFAGDLAYPSKDHDNWDKWMDLMSKRDFFSVIPTQIALGNHDLDTYKHGWIYDINESVEIALAYEHRFHMPQIRPPIREPASLKGFTTSGQPTDFVPYEYGNAYYSFTFGPSKHIVLSSYSSFREGSLQHEWLLSELKSVDRSVTPWLIVMIHCPLYTTFKTHRHEIFITEAQAILEPLFVEYTVNFVIAGHVHAYMRTHPVAFSRRNPRGPVHIIQGNGGKAVCEPYHNETAEEWVAVRDQSQYGYGTLELFNSTHAMWKLIKTGHDEGREFEPNLNLLDEIWVRNQLYVEEMSVNKDWEDNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D750</accession>
    <name>A0AAD9D750_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sulfate permease family inorganic anion transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_012668</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D750"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052706">
        <property type="entry name" value="Membrane-Transporter-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43310:SF4">
        <property type="entry name" value="AFR304WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43310">
        <property type="entry name" value="SULFATE TRANSPORTER YBAR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042101146" evidence="6">
        <location>
            <begin position="21"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="123"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="7">
        <location>
            <begin position="203"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1736646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="497" mass="54769" checksum="A80772C633C254A3" modified="2024-05-29" version="1">MVALVLFSLIHVPINIPAFAVSSDVDVEINAELVAHGYSNGIVGLFGGLQNYMAYTQSIIYYKSGGNGRASSLAVAGLTSVLFFFGPSVASYMPRCMAGTLLLHCGIDLFLEGVSDSYGKYDYLEYAGIWAITVVMTTFGMEAALLMGAVSALLTYAIQSVTYLSPVRGSMTAATLRSSEWNRSPEAFNVLDSDVTGRVKIEVIQLQGHLFFGNISLFGESIKKIIQSNPAGKLPFIVIIDFTLVLGIDSSAAQAIIKLRDQLSHQLGTKLVIFVPGSASGFPCEINISEQLNTARNFSGSHVCEDMDQALIYAEDALIATVNKNLLYDSIKGSFLSNDQKDIISIEDEKSHAIELLFRKCPGESRQVVEKFLSYFTRETYNKGDVLWKQGTKSDSAKLLVSGDLIPSLNTRRKQQRRYRLGALLASRALFKGLIETAPYTYCDNTILYSLSSEAWEIMKKDDLQSAQLLYSIVVRYLTLRVQHVSNRIFETRCLPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D783</accession>
    <name>A0AAD9D783_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D783"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042018393" description="Extracellular membrane protein CFEM domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="113" mass="11201" checksum="2D6FAAAB7A258B3A" modified="2024-05-29" version="1">MKLNLFALVTILGCATNAVLASMCSESSGVCVCSGDCPSFTDDWTSSINSGSTCVATKTASSTSIEDGVVTVNNQTYTIIDPCSVGSSAGIFDAHLATVVVAAVVVAGGVAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7C5</accession>
    <name>A0AAD9D7C5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">D-cysteine desulfhydrase</fullName>
            <ecNumber evidence="6">4.4.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_013732</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ACC deaminase/D-cysteine desulfhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.15" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7C5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019148">
        <property type="term" value="F:D-cysteine desulfhydrase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027278">
        <property type="entry name" value="ACCD_DCysDesulf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43780">
        <property type="entry name" value="1-AMINOCYCLOPROPANE-1-CARBOXYLATE DEAMINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43780:SF2">
        <property type="entry name" value="1-AMINOCYCLOPROPANE-1-CARBOXYLATE DEAMINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041998676" evidence="4">
        <location>
            <begin position="20"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="5">
        <location>
            <begin position="107"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1735569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="468" mass="51037" checksum="C15FA77659DB3F94" modified="2024-05-29" version="1">MSNISLLSFMLLLTSTSRATTAFISSLSTHHPHFELIGSRHNTNRLIMSFEFQQPDARYPYTPPAWASPLTNVPKKRLKLAHLPTPIQLIGANRSTRQQKNSSTILSRLKELNIKLYIKRDDATGGVELGGNKLRKLEFLLADALETGCDSVVTIGGEQSNHCRATAAAARMVGLSPNLILRTRRADKIHEKTDELGFEGNILFDRMMGSTIYTCTPGEYGRVGSNKLVQHVCDYIATKDGGKPYAIPVGGSNGVGSWGYINAVDELMNQMESMKQDNTSSDFNLDHVVFATGSGGTAAGISLGLSMAYGSLGPSATDTSCPKLHAVGVCDNPAYFYDTMALIANEMGASLDKTTNQFIREAVTVHNGKGRGYALSTEDELDFILQLSLETGIALDPVYSGKALYHFVKHVVENDVESYRNKNVLFWHTGGALGIYEKGNDLLHKFSEVSPVKRVNVYGSNGVKEITD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7R0</accession>
    <name>A0AAD9D7R0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013126</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1735990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7R0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="34" mass="4142" checksum="1478F2D1C2CD87BF" modified="2024-05-29" version="1">MLWMISRRRRQGKEFSFCRPESRSTVTRAGRNQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7V3</accession>
    <name>A0AAD9D7V3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Small nuclear ribonucleoprotein G</fullName>
            <shortName evidence="9">snRNP-G</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_012114</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Plays a role in pre-mRNA splicing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7V3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043186">
        <property type="term" value="C:P granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034719">
        <property type="term" value="C:SMN-Sm protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097526">
        <property type="term" value="C:spliceosomal tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005689">
        <property type="term" value="C:U12-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005687">
        <property type="term" value="C:U4 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01719">
        <property type="entry name" value="Sm_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000023">
        <property type="entry name" value="Small nuclear ribonucleoprotein G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044641">
        <property type="entry name" value="Lsm7/SmG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034098">
        <property type="entry name" value="Sm_G"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553:SF2">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9 11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="6"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1737247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="81" mass="8973" checksum="216AB52347FC1F29" modified="2024-05-29" version="1">MSSKHQKGPDLKRFMDKKLKLSLNGNRKVTGQLRGYDAFLNVVLEDAVTETTGGATENIGTIVIRGNSIIQFESVDRIYTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8F7</accession>
    <name>A0AAD9D8F7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Subtilisin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8F7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042167052" description="Subtilisin" evidence="1">
        <location>
            <begin position="22"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="255" mass="26844" checksum="B9643E640BFD73CF" modified="2024-05-29" version="1">MTKLSIVAATTVALAASSVSSFSVTNNNPTRITTSRASSSVLNLIRGEAVDAETFDENEGGVGLALRSAIKISGKCQKDQCDAQELMRYEKMQEVEMSVAQSIMEKSGCSVLCSGMGKELYQDPASTIRYEDKLVKFAPIEAAKAALENVAAAPSDAKYVALNFAGGDDLIIGEILEACGMLVDGLNLEGKPKVSFNSISFNQFADETCSVTVVASGGNTGGLEGVDESIAKGELYAYDGKWFTVAEGDITTAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8G9</accession>
    <name>A0AAD9D8G9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Leucine-rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011186</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8G9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="318" mass="36633" checksum="3D10F72555F3EAB1" modified="2024-05-29" version="1">MMIDVFVYTGGEQEAPRMVRHIIIDRSVKIIPARAFQYRFQLLSVEMHEDVEKIEEFGFDNCHSLTGIKLLGVREVEQFAFFSCDRLCEVEFGDKLEIIGRNAFSGCPIRSMKLPSIRTIEHGAFNNCLQLTEVEFGSYLERIVYDSFIHCHNLRRIAIPLKDSIFSLGTTTGQQQYNHFNHCDNLITVDLVGGVNKTISSLLLQSWKDDLNAEIGFVNELLPNTHVSEKTDLIRQSIPFVIQRTEHYKAEHNKLLKEHMTLLELGIWKAKLDEKEEEFLEGRAKRAEVDVESMRKEKRIKSGASIVIKNFLPFLKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8W2</accession>
    <name>A0AAD9D8W2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Aspartic peptidase, A1 family</fullName>
            <ecNumber evidence="10">3.4.23.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_011071</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.-" evidence="10"/>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8W2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000115">
        <property type="entry name" value="Lysosomal aspartic protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041954238" evidence="8">
        <location>
            <begin position="20"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="9">
        <location>
            <begin position="93"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="303"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="124"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1738402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="456" mass="49574" checksum="61EBD67F51074AB8" modified="2024-05-29" version="1">MLFRSLSLVAALAISSAAADSDDGLIRMKLHKIVSEEDFMMNLLSYHSPPTIKSSSANSLASVATERKLVRGAKQQNHAQEHIVLKNKLNAQYMGEIKIGTPAQSFMVVYDTGSADLWVPHEKCHEEMNCVAKNVFIPSSSTTNKELPSGSKSSFAIHYGSGPVSGVFTIDQVTLGQDDVVSDQTFGLVEHSSGLGALYQKAKFDGILGLAFPILSQNPGAHTVVQNLLAENVIKSHVFSFYVGKDKPGEVAIGGMNEKLMKKETLNCIDIMEPARYWLAEMSDQVKFGGEVVSTGKHAGIIDSGTSLIYGPKAVVMKMALQLGGMFMPQVNLFAISCDKKVPDLEFNFGGKPYVVPGKDLTMKDVTGTHCFLGISMMMFGEEDEESMADVETMDKEVDLGITEDIEKLVGVGESKIPIPAGVTAWLVGDKFMMQQYNVFDVENKQICFAELKEGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D977</accession>
    <name>A0AAD9D977_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011776</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D977"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="186" mass="20871" checksum="8F88BB7E334B06C1" modified="2024-05-29" version="1">MAALFKVPSIKKVIDCSETFIIKDSCDKTAATPTLSTNILSSASSLSSSNSIKDGSVEVIKGVKSYNCKEKNVEIDESDGDELYNLFVKEQDSPQKTDNTAIQETTFPEGVDNVANFINIRKLVGKNETNYYYSKANLSSRKRIEKIKRKKKKRRGTLDNLDESVNSRKNFLTHSIRASAYKVRDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAD0</accession>
    <name>A0AAD9DAD0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tocopherol cyclase</fullName>
            <ecNumber evidence="1">5.5.1.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.5.1.24" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAD0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009976">
        <property type="term" value="F:tocopherol cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025893">
        <property type="entry name" value="Tocopherol_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35309">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35309:SF4">
        <property type="entry name" value="TOCOPHEROL CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14249">
        <property type="entry name" value="Tocopherol_cycl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="422" mass="47190" checksum="39A72EA11F931941" modified="2024-05-29" version="1">MPLAIPILAAVLAATIGILSTTNHFLSEDRLRQTNILKFQPDKFQGGNKQERYFEGWYYKFVSQPISLQSDHHDGRFAVENNTSFSMAVVPGIFYSDASVSNEFHAFIFVTLNGQQQHYYRFDVDQFTYAAANEEYYIQVGKNRFTKDGVSLDLYPQSNDDADLILRGNLKFTNPSPWPVSLLELGAMGSVGWMPGLECTHGILSFDHELSGNLSLATSVNNSSSDATTSSASSLKISMDGGRGYTEKDFGRSFPSLWVWIQTNSFRNNPGTSLFVSLARIPTPFFGIEFPGFTAAIWHNGELIPFATWSGAAFDDIRISKEEVYIAMRSARHGRSKYRVEISVDRRNVPEVLLYAPVNFTRMEPFVWEALRATVHLRLFDGKGNVIIDDMGDYAGLEVHGNVQYLAGNLCGKKTANKLICL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-06-18" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAW3</accession>
    <name>A0AAD9DAW3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Multidrug resistance-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_010426</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000838">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000013">
        <property type="entry name" value="ABC transporter C family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF456">
        <property type="entry name" value="MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN LETHAL(2)03659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1025"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1143"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="184"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="531"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="886"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="1242"/>
            <end position="1483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="271"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="834"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="849"/>
            <end position="864"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1739110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1496" mass="163418" checksum="537D3F70253AA816" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBT1</accession>
    <name>A0AAD9DBT1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_008988</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBT1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="entry name" value="Integrin alpha, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013519">
        <property type="entry name" value="Int_alpha_beta-p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36220:SF1">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX COMPONENT C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36220">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14312">
        <property type="entry name" value="FG-GAP_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00191">
        <property type="entry name" value="Int_alpha"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="Integrin alpha N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041956397" evidence="5">
        <location>
            <begin position="19"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="90"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="102"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="159"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1740038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="635" mass="69562" checksum="055F898873E83697" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DC12</accession>
    <name>A0AAD9DC12_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009228</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DC12"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="422"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="449" mass="49233" checksum="095C18E74E4F0A7C" modified="2024-05-29" version="1">MFPTDGTILTVSPDDAQPSAVVDDNILTDDELPPTSSGEEESNELPADYSSLPETLMMTSNAENEGKSAPEAETVDKTPTLSSDQQKVSNEPTGIEEEFQDENQAEVQLPSEDNVSTELDTSCAEKATATINEERQEEIIEERTDTEGCVDDTFVSVELSSSPSKNNSSYEEVGGQQEQEPLIDAASVSDTAAATVLINPSSEVAATDAAMASYVSSDNDDVAAASKSSFNISSQPPTTTTTTTTRRRKILHHPILSHLTKLPWDRLSNAGSACDVLFNCKYSMKQVEDEVREECRRGVSGEGVYIENDGVGREDGYVNVSLNSCSDYQYQEEGCETGEFEQILGCCSMLDNDEETDDEEEDVECVLPENYVVASEKAPHLVQPMIGLEGSHATVYTNQEEGEEEREYSGDNRVNSNGNELQQQQQSEKSWQQANPSLDMMLYRQFLNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCI6</accession>
    <name>A0AAD9DCI6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transcription initiation factor TFIID subunit 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_007121</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCI6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.500">
        <property type="entry name" value="TFIID subunit TAF5, NTD2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007582">
        <property type="entry name" value="TFIID_NTD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037264">
        <property type="entry name" value="TFIID_NTD2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879:SF1">
        <property type="entry name" value="CANNONBALL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04494">
        <property type="entry name" value="TFIID_NTD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160897">
        <property type="entry name" value="Taf5 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="TFIID subunit TAF5 NTD2" evidence="9">
        <location>
            <begin position="418"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="850"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="984"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="1019"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="106"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="281"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="348"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="521"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="884"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="172"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="281"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="348"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="521"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="533"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="885"/>
            <end position="911"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1742556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1176" mass="125426" checksum="81F88505E4D8EE2D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCZ8</accession>
    <name>A0AAD9DCZ8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-directed RNA polymerase III subunit RPC6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_006379</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCZ8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006383">
        <property type="term" value="P:transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000116">
        <property type="entry name" value="DNA-directed RNA polymerase III subunit RPC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007832">
        <property type="entry name" value="RNA_pol_Rpc34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016049">
        <property type="entry name" value="RNA_pol_Rpc34-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12780">
        <property type="entry name" value="RNA POLYMERASE III DNA DIRECTED , 39KD SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05158">
        <property type="entry name" value="RNA_pol_Rpc34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1742782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="318" mass="35707" checksum="D333884F384000E6" modified="2024-05-29" version="1">MPPKRPPSIAIATAATKRRRGTAIKPIVSMAVSTSVGTSYQDDDGEDSNPLRKEFLQLLSAPQYKGRGVANSALKAHFGDKYTQLVPIINELTRASRLTMSKANGENEVYFSLLSAVEASKMQGLDAHSKLVYQVIESAGNKGIWTVDIRVQTNIPQATLTKIFKQLETRKLIKPIKAVTAKTKKLYMLYDLVPAKEITGGPWYTEGEFDHEFIAELRNFIIMCVRRMNRGKGVSIQQISDKMVQANVSRVQLSLEEVRQLVQTLLHDYVIEERGVTDDGMALFVPAKKITTMCEFGWWDVCVRTFILGGLDLRMMWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDQ1</accession>
    <name>A0AAD9DDQ1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDQ1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="104" mass="11576" checksum="ECF461BF598C6AEC" modified="2024-05-29" version="1">MSYIRSGNYSEACYKATEPPYFVCINMTPDEWVEKALETYPRCCGVDLSECTCPVKDYWFFKNKIADYCAKVDVCGPPAIAAESSESSGGDARFLRGQAEDANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDQ4</accession>
    <name>A0AAD9DDQ4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ribonuclease H</fullName>
            <ecNumber evidence="3">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_007593</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNase H family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDQ4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd09279">
        <property type="entry name" value="RNase_HI_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.970.10:FF:000001">
        <property type="entry name" value="Ribonuclease H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.970.10">
        <property type="entry name" value="Ribonuclease H1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_bL9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011320">
        <property type="entry name" value="RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037056">
        <property type="entry name" value="RNase_H1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46387">
        <property type="entry name" value="POLYNUCLEOTIDYL TRANSFERASE, RIBONUCLEASE H-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46387:SF2">
        <property type="entry name" value="RIBONUCLEASE HI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01693">
        <property type="entry name" value="Cauli_VI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13456">
        <property type="entry name" value="RVT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="L9 N-domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="9">
        <location>
            <begin position="99"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1742020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="321" mass="35037" checksum="0F85EB73CD8522A0" modified="2024-05-29" version="1">MPKSKWYAVARGRSPGIYQTWDACKAQTAGFSGALFKSFKTHDEAKAFITSNTTSATITAAPSSNNTVGKKRARDVKDVSSHTAQNKRSIQHPFKNNAARFCLTIYFDGGSRGNPGVAGCGAEVIAVNNAMNPPITTKYLIREYCGDRETNNYAEYNGLIAGLKQARTLISELVGADTSSSSSTGTSVSVSKPVLKLQIYGDSNLIIQQLKGNWKCKHEGLKPLYHQCQRLIADIKNKVANSEVSYDHVYREQNKVADQLANEAMDQRRSWITSDADNVRTARVGVVKVLKTSRHAVGVTAARKTSREVIDLLDSDGSHSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDU2</accession>
    <name>A0AAD9DDU2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005533</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDU2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="2">
        <location>
            <begin position="604"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="492"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="562"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="677" mass="74725" checksum="0B4636726F3B80D4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DF87</accession>
    <name>A0AAD9DF87_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PWI domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006109</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DF87"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048024">
        <property type="term" value="P:regulation of mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1390.10">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002483">
        <property type="entry name" value="PWI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036483">
        <property type="entry name" value="PWI_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052225">
        <property type="entry name" value="Ser/Arg_repetitive_matrix"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23148">
        <property type="entry name" value="SERINE/ARGININE REGULATED NUCLEAR MATRIX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23148:SF0">
        <property type="entry name" value="SERINE_ARGININE REPETITIVE MATRIX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01480">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00311">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101233">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51025">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PWI" evidence="3">
        <location>
            <begin position="22"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="150"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="215"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="173"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="215"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="262"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="281"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="293"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="329"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="389"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="429"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="447"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="484"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="517"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="532"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1743488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="578" mass="64501" checksum="36C165280768D56D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFF9</accession>
    <name>A0AAD9DFF9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004742</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFF9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042266850" description="Fe2OG dioxygenase domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="469" mass="52442" checksum="581EF5ABB262DBEA" modified="2024-05-29" version="1">MKHSKASILSVALIAGLATVNAAEPLEKDFKYKDALKYYHTETSALLKQSLLSAGFAIDETNEVDDIYLDFASRALNAEKERIERIRDALASQTCSEGDGQCTPPPAKKKIDKSKYSPGFGHFLTHDLEPGQAELMRWEHDGSIVQDYAVRVGLPPDLVPTIKAYVKDMGLLDIMTNMLYDDPLSPGDAKWFTFQSPYQKANLAEGSTTDELRNFTWNVERPDKKWKSDMHWFNTADELSHEEGLRVLAKGGFDQVLAGIGEKMGLDSLNIDSFGFVAVTNCDRGFIHTDWEDVDGRAFNFLVGIESPDQAGPELIVEGDFKGEIYYGSNAGILVGDGTRHGTRECDHRAYRGVRIACSIYLSDVTKDNLETLAGDTTSIFPPTGKTAADWVWTQGGRHWSKKGGRSLVDDVGRKPFNVEDEMEGCKKHLCIRDDDEGRYRNSCMKTCNVFMNDEDYKPGTERREVYGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGB8</accession>
    <name>A0AAD9DGB8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGB8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="387" mass="42774" checksum="F10681C2314434D0" modified="2024-05-29" version="1">MNTMPSPTTTNTLQPEAPPSSPEVALKNKSLTTTAGMMMDQTPKHRNTSTNALSKLDYSEDYDGVNLTEGDLRPSRGSTAINSAAINNGAAINNGARRFPGMRTAAPPPDYNTTTTSRLRPPHPSTTAAYHHHPTSHREYGRQYEGSYDDYIHDLSAPLPDYDVPPTYSLFGRDPHHRGHHHRELPREHRMPRERIVDYHSGGGRGPPPHHYYRPPPPQYYDYYDGYYRDHDYRPSGSGGGEVNGGGGEGRSYWEGGRPQPTTTTAPTVGNGGGGFGEERMNHHHSMEHADSTGDLTHQERGMVVEGTAKEEGKSLRAVSGSFSVTASKSSEGSLVEHLSKDGGGEERQQGNDNKEQHKVKMVVQMRRIRILPWCCVDGWIDKECCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGM3</accession>
    <name>A0AAD9DGM3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004416</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGM3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.980">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="304" mass="34417" checksum="B63F2FA2AA73CD1C" modified="2024-05-29" version="1">MLHNATARSLMRMNRMSGWRRKRRKRRLSSKPPPKPPNTIQQHERLLQQHRLALPRPPLLIFQPPQQWHINTRDEPTSNGNHQCWRCPRSIGSDHPHQEIIRYEHKNVKWTLKHVNYYADALACGLVDSGLQPGDVVLSWLPMHLAEQHILQFACSKAGFLLYHLDPNPALAKSNPDKAKPPSPRPSNLQMPMSSSPKKQAMMSIMLISLKGLFLKYAFSTLERACPSSPPCIRVTASLIKRACTHSNISWYLAIIWTACFVVQSKALDGKTPLLGELVLDNDGIPVKTGKVMTMKRSSKQGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHQ3</accession>
    <name>A0AAD9DHQ3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHQ3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="362" mass="42182" checksum="B6E51EC5F2B886DB" modified="2024-05-29" version="1">MSQITKRIHVSVNNADKNDYFITDISAATSRRNGRVAASESNRIRLLGMVVFFTTVIVFFTSDVDFTTWVPMKHTKKDIERKEYPIQMLQDVPTVAEIESTLQREYRRIHGDSIEDMARVRLHSLAHTYALTYKLIHELQKQQIHVTLTFGSHLGALRHHGVIPFEEKDVDLAVFSTNTSKIKRAIRATLRTQPHLNLTFSEAYFGFQIPATKELQTYIDVWMFKNDASQTTCVGHQLPDKSCKKWYRDFHDKPPPIYRHDAWFPFRTELFGTERVPIPATNIPIESFHFDDGGPNFWNKTCGPDRRWWEKGQKWLQVDMRERKCSHKYNAYPFVFKKANGIEQLRQGSVVIHEVDGVSLHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIE5</accession>
    <name>A0AAD9DIE5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mitochondrial cardiolipin hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_002613</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the phospholipase D family. MitoPLD/Zucchini subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIE5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016891">
        <property type="term" value="F:RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09172">
        <property type="entry name" value="PLDc_Nuc_like_unchar1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051406">
        <property type="entry name" value="PLD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43856">
        <property type="entry name" value="CARDIOLIPIN HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43856:SF1">
        <property type="entry name" value="MITOCHONDRIAL CARDIOLIPIN HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="6">
        <location>
            <begin position="592"/>
            <end position="623"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1747269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="703" mass="78689" checksum="4A4E673B564F0D86" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIF6</accession>
    <name>A0AAD9DIF6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002087</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIF6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045159">
        <property type="entry name" value="DCAF7-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19919">
        <property type="entry name" value="WD REPEAT CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="45" mass="5120" checksum="5F63A2E367091CA4" modified="2024-05-29" version="1">MSKRSVEDPILAYNAEAEVNNLQWSSSQPDWVSIAFANKLQILRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIN3</accession>
    <name>A0AAD9DIN3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Glycylpeptide N-tetradecanoyltransferase</fullName>
            <ecNumber evidence="2 5">2.3.1.97</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_001230</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>N-terminal glycyl-[protein] + tetradecanoyl-CoA = N-tetradecanoylglycyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15521"/>
            <dbReference type="Rhea" id="RHEA-COMP:12666"/>
            <dbReference type="Rhea" id="RHEA-COMP:12667"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57385"/>
            <dbReference type="ChEBI" id="CHEBI:64723"/>
            <dbReference type="ChEBI" id="CHEBI:133050"/>
            <dbReference type="EC" id="2.3.1.97"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the NMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.97" evidence="2 5"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIN3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004379">
        <property type="term" value="F:glycylpeptide N-tetradecanoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000903">
        <property type="entry name" value="NMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022677">
        <property type="entry name" value="NMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022678">
        <property type="entry name" value="NMT_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022676">
        <property type="entry name" value="NMT_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11377:SF5">
        <property type="entry name" value="GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11377">
        <property type="entry name" value="N-MYRISTOYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01233">
        <property type="entry name" value="NMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02799">
        <property type="entry name" value="NMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00976">
        <property type="entry name" value="NMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycylpeptide N-tetradecanoyltransferase N-terminal" evidence="7">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="Glycylpeptide N-tetradecanoyltransferase C-terminal" evidence="8">
        <location>
            <begin position="86"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1749291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="274" mass="31118" checksum="05B929D6D5C5BEEF" modified="2024-05-29" version="1">MALITAVPAKVRVYGEEKDMAEVNFLCVHRKLRSKRLAPVLIKEITRRVNHTGVFQAVYTAGVKLPGSVASCRYYHRTLEARKLVEIGFTRLAPRMTMARMQKLYKLPAEPNTKGLRPMTPEDVPAAHKLVVKYLEKFQLAVVFSEDEFAHWLLPRKGVVSSFVRMDADGVITDFCSYYHLHSSVLGNPKHNTLNAAYSFYNVAKTVSLTALMKDCLTLAKNEGMDVFNALNLMENDNFLEELKFGMGDGNLQYYVYNWFCPTMQHNDVGLVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIZ0</accession>
    <name>A0AAD9DIZ0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Mitochondrial carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_001847</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIZ0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990547">
        <property type="term" value="P:mitochondrial phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044677">
        <property type="entry name" value="SLC25A3/Pic2/Mir1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45671:SF12">
        <property type="entry name" value="MITOCHONDRIAL PHOSPHATE CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45671">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25 (MITOCHONDRIAL CARRIER PHOSPHATE CARRIER), MEMBER 3, LIKE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042247280" evidence="12">
        <location>
            <begin position="19"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="132"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="228"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="329"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1747884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="422" mass="45174" checksum="91F8F78A63DCFB16" modified="2024-05-29" version="1">MIMKRLLFHVLCLQVAAAFQLSHYHHPRHNDCRHRHVTITAGAFISEHEEQFGDVIDRRAFVRNALLTLSILSIKPDNAMAATDDDLAPAAATPSILEGELIVSSPPPNREIVTDDEDMSSTPVAQVSKKKTSDPRFFIAGGASAAISHGITTPLDVVKTRMQSDASLSDLSPPDAALRIVETEGPKALTAGLAPTVIGYGIEGALKFGVYETLKPIFLAACDGIVTDPTQPYLVAAICAGALASIILCPMEETRIKLVTDPSFANGLLDGLSKIVKEEGILSPFQKGLAPMLSKQVPYTMGKQVSFDLFAGMLYSTLLGLTFLPKNGIALEVEVGAAFMASIVACLASHPGDVLLTATYKDSDGTNGNFFETIQRVYQDGGILAFFRGLNARFIHVGCIITFQLVIYDQIKQSLGLPASGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1LVE1</accession>
    <name>A0A8K1LVE1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cytochrome b6-f complex subunit 7</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Cytochrome b6-f complex subunit PetM</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Cytochrome b6-f complex subunit VII</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">petM</name>
        <name evidence="9" type="ORF">QTG54_017205</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="10"/>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2021" name="Front. Plant Sci." volume="0" first="0" last="0">
            <title>Chloroplast Genomes for Five Skeletonema Species: Comparative and Phylogenetic Analysis.</title>
            <authorList>
                <person name="Liu S."/>
                <person name="Xu Q."/>
                <person name="Liu K."/>
                <person name="Zhao Y."/>
                <person name="Chen N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CNS00100</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">The 4 large subunits of the cytochrome b6-f complex are cytochrome b6, subunit IV (17 kDa polypeptide, PetD), cytochrome f and the Rieske protein, while the 4 small subunits are PetG, PetL, PetM and PetN. The complex functions as a dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast thylakoid membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PetM family.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MW679506">
        <property type="protein sequence ID" value="UAM91406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_010200918.1">
        <property type="nucleotide sequence ID" value="NC_058701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1LVE1"/>
    <dbReference type="GeneID" id="68638051"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009512">
        <property type="term" value="C:cytochrome b6f complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00396">
        <property type="entry name" value="Cytb6_f_PetM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012595">
        <property type="entry name" value="PetM_cyt_b6/f_cplx_su7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08041">
        <property type="entry name" value="PetM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103441">
        <property type="entry name" value="PetM subunit of the cytochrome b6f complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4 7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="10" id="KW-0934">Plastid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1732162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UAM91406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="42" mass="4489" checksum="602ACF1E37873215" modified="2022-08-03" version="1">MALVLQIFPFANAEIVTAAVTCIFMTLFGLSLGFALLKVQGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XR75</accession>
    <name>A0AAD8XR75_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Tim17 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_016991</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tim17/Tim22/Tim23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000073">
        <property type="protein sequence ID" value="KAK1732324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XR75"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10485:SF0">
        <property type="entry name" value="AT05822P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10485">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="183"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1732324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="237" mass="24217" checksum="D5609708469CC129" modified="2024-05-29" version="1">MRNHSIADRDPCPYRIIEDIGGAFAFGSVGGGVWHFGKGAWQSPKGTRLMGAIGNCAARAPVMGGQFAVWGGLFACCDCSLTAIRQKEDPWNSILSGGATGGILAARAGPKAMASAAVIGGVLLALIEGMGIWMNNYFAQQPMGMEDPNAAGGMVTGPPENDITAPPTSGGVGMMPTGLTLRRAPSQQQQQTIGGMEGESERFDSGGYETTFSSGGGGGSSSSGDEKSGGWWPFGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRA9</accession>
    <name>A0AAD8XRA9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF2252 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_017032</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000077">
        <property type="protein sequence ID" value="KAK1732257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018721">
        <property type="entry name" value="DUF2252"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39441">
        <property type="entry name" value="DUF2252 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39441:SF1">
        <property type="entry name" value="DUF2252 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10009">
        <property type="entry name" value="DUF2252"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="610"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1180"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1768"/>
            <end position="1856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="627"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="641"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="668"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1197"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1211"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1222"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1248"/>
            <end position="1262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1785"/>
            <end position="1798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1799"/>
            <end position="1809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1810"/>
            <end position="1827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1836"/>
            <end position="1850"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2327" mass="263463" checksum="2745A49BC86F2BE1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRS1</accession>
    <name>A0AAD8XRS1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_016929</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000068">
        <property type="protein sequence ID" value="KAK1732394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049227">
        <property type="entry name" value="DUF6824"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20710">
        <property type="entry name" value="DUF6824"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6824" evidence="3">
        <location>
            <begin position="8"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="2">
        <location>
            <begin position="422"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1732394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1378" mass="150604" checksum="22038535483E6CF5" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRW8</accession>
    <name>A0AAD8XRW8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosducin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_016932</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000068">
        <property type="protein sequence ID" value="KAK1732397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRW8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21148">
        <property type="entry name" value="THIOREDOXIN DOMAIN-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="199"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="46"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="138"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1732397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="352" mass="40007" checksum="AC00C7CBE26461C4" modified="2024-05-29" version="1">MPPSSNQNPLGNSKAAKFVAANPLAPLADPFSGISGAEDESTALQKEVSNNVQKRLETAMEELKEKHRTGTNEVDDVDRAPTGTAYRELHRRQREVAKVSAASRQKEAERSRMEENQQILNVREHMRRMNFGEKENADNYDDDQDGYSSSEDDDEFDHLLDEENDEELAAIRQARIAQLKQQQSQHATNLSLGHGSLRTINESEFLAECTGSSKYVIVHFFNDEFERCKIMDFHLKIVAEAHVEAKFLRMDAAKAPFFVTKFQVRTLPSLFVYEEGREIGRLTGFDGLALNAKKPDEWHTGRLQEWLSETTGAIWYEKPSEEVAEEMKRMGIVMRGAVYSDRQRSGLVDDDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XS29</accession>
    <name>A0AAD8XS29_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_016881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000066">
        <property type="protein sequence ID" value="KAK1732487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XS29"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1732487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="82" mass="9187" checksum="3B606632419F6154" modified="2024-05-29" version="1">MQQLLILLSTPLHLSHGRIQPFIPPCLALLGRFAIEEGGDAGPLLFSVFHYGGFEDFIFGVFPDSAFDEDAHHGWILLLFIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTP0</accession>
    <name>A0AAD8XTP0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_016029</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000051">
        <property type="protein sequence ID" value="KAK1733312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTP0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="161" mass="18098" checksum="61B9394252C314E2" modified="2024-05-29" version="1">MKNNSTKNTVNNDAVINGDFITTLTVPTKGEASTDEALKRVIDTRNLSEEDLNALRKQDPFLYYSIQSARNAALRRNFSDDLTALHNQEEVARSRSRRASCPSRVESTMVERKSCISFERHPDLLLEDCMDEAELFGDGAGAGLDTDALFDQLLLRSKRQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTU0</accession>
    <name>A0AAD8XTU0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peroxidase</fullName>
            <ecNumber evidence="9">1.11.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_015619</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the peroxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000045">
        <property type="protein sequence ID" value="KAK1733764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTU0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF36">
        <property type="entry name" value="L-ASCORBATE PEROXIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="8">
        <location>
            <begin position="37"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="282"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="286"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1733764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="320" mass="35224" checksum="B280AFEE3B06433C" modified="2024-05-29" version="1">MGADGCIDWQHEANNGLETIWCVDGCPLTQIYQEKYSVMSRADFWVASANAVVKLSSPNNELDLKSTFKWGRVDAEQCPDSALRLPGASDCGQVQDVFLNRLGLNWTDAVALIGGHTLGRGSSDFSGHEGIWVDMDAEATIFDKRYYEEVLRKTWVPRNEGTDVQDWTWGGNNDGSPRFMLNTDMCLLFDIETTFPCCSRTDLTRNDGTNQCDRRNSVLSDTQCSRTTNEDAANAMLQFAAQRDDGRFTNDNEPFFTAFSVAWEMATINGWDNLQELALSCVPTESPTPAPSTSPTLNPTPVPTAPPTQSPTAPPTPGPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUY6</accession>
    <name>A0AAD8XUY6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015245</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1733987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUY6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="236"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="183"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="260" mass="30124" checksum="08C07714113E1171" modified="2024-05-29" version="1">MLLESLYLHHVNLGDEGALVLADALIGNKSLTSLRFHPNDSGITDVGRAAFSNLLCDPSSVNNTYLSNHTIEKIGGYQSNLHDIAQFLRFNRLSRHPHEAAIWKILKSHPDLDMEPFFQWKLKLLPVVTNWFRSARSCLFPDRPKSMQRQTLQNRELSALYKFVRGMPSLAVISYWQQFTVNAQAKRRRIDDVVRRLEDERQRLEDERRRLEDERRRLDGERSTLDYDEEAAWVRLGGRPTGEGEGSSDFFSGAKRRRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV43</accession>
    <name>A0AAD8XV43_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heat shock factor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_015167</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV43"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF206">
        <property type="entry name" value="HSF-TYPE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="6">
        <location>
            <begin position="76"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="347"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="303"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="364"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="385"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1734164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="424" mass="47104" checksum="641509F9760F88A0" modified="2024-05-29" version="1">MPKDNHDAIKSDLDGLLVHYWDNQLVVMPPSPPPVVHNGRKLPTTAAAASGAGRGLMKGTPPSTSDEDATKSDFLQGKTFVQKLHTILEVPKYSSIISWNDAGNVATIHDADAFISTIVPAHFKKSKFGSFIRKMRRWGFSAITKKCTSPSEEGPDTVVEFSSEHFLRDQPDLCLLMKDERHVKKQFSFLDRTVTNVNYENINQGSTVGLNAHYSPNAANYHSESQRSGVDNSIPPMISPNQQRQSFHGAMPMMNTMMPPPPPSQLKYPPYGYGAPHPPRLGYGPTSPSFQYPAPDGYPPYPQQQHHQMMPQNSQQQKMMQQYQQQEHQEQLQQQRQRMMLNQEFTSPSADPNLAAVSGKRKAVTSNTRSEFTETRVSTAKASGSAAVLTSSSEESAELLPNTKVDVNVQIHSRLDAEQDASTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVQ8</accession>
    <name>A0AAD8XVQ8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014624</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVQ8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="443"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="462"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="584" mass="63346" checksum="22BC5706C1F4BF03" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW54</accession>
    <name>A0AAD8XW54_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Reverse transcriptase Ty1/copia-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014793</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000038">
        <property type="protein sequence ID" value="KAK1734545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XW54"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09272">
        <property type="entry name" value="RNase_HI_RT_Ty1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11439">
        <property type="entry name" value="GAG-POL-RELATED RETROTRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="286"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="308"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1023" mass="114782" checksum="EEB1A8586702706D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWH9</accession>
    <name>A0AAD8XWH9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-oxoacyl-[acyl-carrier protein] reductase</fullName>
            <ecNumber evidence="4">1.1.1.100</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_014255</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWH9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF83">
        <property type="entry name" value="(3R)-3-HYDROXYACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1735189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="293" mass="31079" checksum="B663055F3E4FEEF1" modified="2024-05-29" version="1">MWLRLANQTAIVTGAGSGIGRAIALALAEQNCNLFLTDVHSENLEHVVAECTKVVPNNNISVESSVCDVRDKLQVEQAIRKADVFASSSSAAAASFSVASILVNCAGITRDGRVTNLSDSDWDDVLDINLKGTFLMCKHFCEPGRAASLLTGSDTTHHNGTGGGSIINVGSIISEYGNMGQVNYAASKGGVVGLTRSLAKEMALFSHKIIPEEGVAEIIPPSIRVNCIQPGFIHTPMAHAVPDKIMSQMKQRIALRRLGQAEDVANLALFLASNARSGYITGEVIECSGMLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWJ3</accession>
    <name>A0AAD8XWJ3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">CDC20/Fizzy family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_014462</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat CDC20/Fizzy family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1735002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWJ3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010997">
        <property type="term" value="F:anaphase-promoting complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990757">
        <property type="term" value="F:ubiquitin ligase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905786">
        <property type="term" value="P:positive regulation of anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000025">
        <property type="entry name" value="FIZZY-related 2 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033010">
        <property type="entry name" value="Cdc20/Fizzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056150">
        <property type="entry name" value="WD40_CDC20-Fz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918">
        <property type="entry name" value="CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918:SF1">
        <property type="entry name" value="FIZZY-RELATED PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24807">
        <property type="entry name" value="WD40_CDC20-Fz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CDC20/Fizzy WD40" evidence="10">
        <location>
            <begin position="505"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="551"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="646"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="778"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="42"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="144"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="283"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="354"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="49"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="79"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="144"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="186"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="296"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="354"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF24807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1735002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="836" mass="89596" checksum="A8AC0ABCA46C8D48" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWL2</accession>
    <name>A0AAD8XWL2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Enkurin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014374</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWL2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="164" mass="18415" checksum="2C63A137697AFD9F" modified="2024-05-29" version="1">MTAVTKTSLTTASSSTTSSGSSNVGSRHNDSYPDEILARNTIITFEKKSNKDVKCPKEQVSKLIEKNESAPKCYVATILPRRNSITHHPELSPISSQSVAVAEAKNIRRLRREVLGLYRTLDTLKKDSREWMLLKSKLDAAREELDAVLEDQQLVRSIETVKTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWM9</accession>
    <name>A0AAD8XWM9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014404</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWM9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="122" mass="13298" checksum="4940FA3C49D5DF17" modified="2024-05-29" version="1" fragment="single">MASESSQQRSMMYLSNLSTTGALTHVSSYLAAPSRALFAVALNSRDSSSAIVGDDWEYLDFGHIEKDLAAKLIDDDIRDVLLSIDAINNLKRLRLTNCINISGVGLEPLRGSTIIQQIDLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XX76</accession>
    <name>A0AAD8XX76_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_013931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XX76"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1735317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="235" mass="26562" checksum="3257972661478670" modified="2024-05-29" version="1">MECPLDGSFDPPGSELIIDYAKIRSMDKSPLKLVQDFTTEQYVKFMLADAGTEHYPFLNYLSATYGDCRHFSDIGTRVVASAAALGSNLKSPVWTFDIPQSIERHAAYRGDTEANYQAKAKSIGLNIKFHNLDLLKVSDEELKKYFGTWFVMLDTFHKPDTVPFEREFFQRLLDIGFKGILGLDDIHLNDEMKKWWKELQDGAVVGGYTTYDISEVGHFSGTGLVDFSGKMVIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XX77</accession>
    <name>A0AAD8XX77_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013967</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XX77"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="975" mass="108666" checksum="A2002C784C736CE0" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXC6</accession>
    <name>A0AAD8XXC6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TIP41-like family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014226</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TIP41 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXC6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031929">
        <property type="term" value="P:TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051330">
        <property type="entry name" value="Phosphatase_reg/MetRdx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007303">
        <property type="entry name" value="TIP41-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21021">
        <property type="entry name" value="GAF/PUTATIVE CYTOSKELETAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21021:SF16">
        <property type="entry name" value="TIP41-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04176">
        <property type="entry name" value="TIP41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="445" mass="48938" checksum="412EA0ADA5871B46" modified="2024-05-29" version="1">MAPSSRRQVLPPETLAAFGASPIYSSSGSDDGDNHSAPPSSSQFSKYFANTTSVETPIIGVKIGGWTISTQNSSIGDEQSMEKLTVLLEEIANSQDGANDDVHQLQPVVRQRRLCPPEITFLDAFISLRHENNSNHDGNDTANDAHENITTSSEIRFNATDALSEWAEAHKSLETQPTDEAENDIQVSLSNQRKECRGVTILRTLDAKVWSTKSKQLTDDTASDSGGTAAHSSEFYYDWTFSSPYAGTILTTSNSNSSSKNLINNRQEWQPLPKSQIPFHLLQDTSQPILLYDDIHLFEDDLHDNGESSLNIKIRVMPKCWYVLQRLFVRVDYVCVKCREVRYFCLLDGNDGTNAEATIASSVGNNCKPNVVYRDVTWREASWAELNKMNLPMDPSAWMEHNLSASGGGIGGNISTGVPSFASLLTKLPAVSTPDDLKKHSGGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXF7</accession>
    <name>A0AAD8XXF7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TraB domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXF7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14726">
        <property type="entry name" value="TraB_PrgY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002816">
        <property type="entry name" value="TraB/PrgY/GumN_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046345">
        <property type="entry name" value="TraB_PrgY-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21530">
        <property type="entry name" value="PHEROMONE SHUTDOWN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21530:SF7">
        <property type="entry name" value="TRAB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01963">
        <property type="entry name" value="TraB_PrgY_gumN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042146343" evidence="1">
        <location>
            <begin position="25"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="373" mass="41340" checksum="3C845C292CD44EE5" modified="2024-05-29" version="1">MMMLKLCLLFAVFLSSWPSDDVRAFMATLPTRQLQATSPSLLLFAGRAASSLPSATVSVEDEEDESTVISISNQNTGQSVTLIGTAHLSEKSNKQVRRLIETLQPNAVMIEIDPSRLERLGFSNVDEIKIATVTDSEDIELPIAPRKTKGGGLMRFAQEASIGVFSQVARAVLTQIYKSLENDMDQKAGGEFLQAVQSAESCTACDTLILGDRNSITTISRVAELAIDSGDFMGVLNRLQAVNQEEIDTLEPKVRKELLIQKGQEGNDDYELDKTELTTAIIETLKDDEMYRTRLFARLEQDVPEFFQAFLKERDYLMSESILREFEKRPEEVKTIVGVVGLAHVPGMERHFKSVFANQPAPLVQDIATVSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYW5</accession>
    <name>A0AAD8XYW5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_013611</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYW5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="581"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1735905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="608" mass="68304" checksum="DB7084994BBB1149" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZ94</accession>
    <name>A0AAD8XZ94_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF814 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_013328</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCDC25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZ94"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039730">
        <property type="entry name" value="Jlp2/Ccd25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008532">
        <property type="entry name" value="NFACT_RNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13049:SF2">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13049">
        <property type="entry name" value="DUF814-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05670">
        <property type="entry name" value="NFACT-R_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NFACT RNA-binding" evidence="3">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="136"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="136"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="203"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1736192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="212" mass="24836" checksum="87528EB86CA11FF0" modified="2024-05-29" version="1">MVFYFKTRCGQYTIYMGKDKYENEDLIKYGHPEDCWFHVDDLSSAHVYLRLHAGQTMDDIPEDCLTDCCSLVKANSIQGCKKSEVYIVYTRWKNLKKTASMVDGQVGFHRPENVRRCKIAKNNTIVRQLEKSKEELHPDLAQEQQARMREIQKQNKAQRILDQKKKKMEELERKREKEERSYDRIVGGETSVSDMNGTADATAAEDYEDDFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZT3</accession>
    <name>A0AAD8XZT3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cas1p 10 TM acyl transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012676</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZT3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012419">
        <property type="entry name" value="Cas1_AcylTrans_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07779">
        <property type="entry name" value="Cas1_AcylT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="345"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="369"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="406"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="449"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="512"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="540"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="domain" description="Cas1p 10 TM acyl transferase" evidence="2">
        <location>
            <begin position="226"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="642" mass="71691" checksum="D2623C0E4480BF1A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZZ0</accession>
    <name>A0AAD8XZZ0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RsmB/NOP family RNA methyltransferase</fullName>
            <ecNumber evidence="8">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_012358</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZZ0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001510">
        <property type="term" value="P:RNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22808">
        <property type="entry name" value="NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22808:SF1">
        <property type="entry name" value="RNA CYTOSINE-C(5)-METHYLTRANSFERASE NSUN2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="7">
        <location>
            <begin position="135"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="49"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="382"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1736913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="506" mass="55404" checksum="566AEE8C6472874F" modified="2024-05-29" version="1">MPKRKKSGSNNPLSSARKDVGGLWHRKSGAGYHLFLSYYGNQPIGVVTTEGDSHQSKSAITAPQCDGNKAAMGNSRAAKKRRRKKNGSNSASSADTNVIAATSTTSSSSQEVDASHPLMQAFNSDSNKYAHLTNFIHALSRPLPLTLRIRKHESADSSELTQTLSRNFSNFVSPVAYDPTKQIYQSTPGSNLCKFNLGHQSPELKSIVVDASMNGTLARQELGSMLPVLSLEAVDAIRKGSKVLDMCASPGSKTLQALEIVVSNSDTKTRGRVIANDVHPKRLDSLRDAVHRSGVPAEELTNRVTYTNFDASVFPFPKSKKLFDAIICDVPCSGDGTIRKDPHILPMWSPRTSNELHGLQLKILLRAMELIKKGGVVCYSTCSLNPIEDEAVVSAALREMNADGNSYQLLDWPEDLLPGFTRRPGVDAWNVGFYDANNLEKDDDDFGSLSFYDSYDSAVEAEVEEAKESFWPNSANNKHSLHCCSRLFPQDQDTGGFFVALIKRIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y086</accession>
    <name>A0AAD8Y086_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Frataxin</fullName>
            <ecNumber evidence="4">1.16.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_012512</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the frataxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.16.3.1" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y086"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004322">
        <property type="term" value="F:ferroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034986">
        <property type="term" value="F:iron chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.10">
        <property type="entry name" value="Frataxin/CyaY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002908">
        <property type="entry name" value="Frataxin/CyaY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036524">
        <property type="entry name" value="Frataxin/CyaY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020895">
        <property type="entry name" value="Frataxin_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16821">
        <property type="entry name" value="FRATAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16821:SF2">
        <property type="entry name" value="FRATAXIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01491">
        <property type="entry name" value="Frataxin_Cyay"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01219">
        <property type="entry name" value="Frataxin_Cyay"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55387">
        <property type="entry name" value="Frataxin/Nqo15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01344">
        <property type="entry name" value="FRATAXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50810">
        <property type="entry name" value="FRATAXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0410">Iron transport</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1736490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="243" mass="27884" checksum="15287011CFE4B4A2" modified="2024-05-29" version="1">MSNCLGRRMASQFCRRQHSSIKSSPHVLKSCSAHYQPHQVETGIQSRKLSHAEGACSTLPRTLFNNTSRSEHYIQQHRYTTASLRCNVNKPGRNNYVMCCQIRLFQNVSQYHNVADDTLHTIQDAVEDLIEDNFDNDTNNSDDDTLPEVNYASGVLTMSLPPHGTWVINKQTPNQQLWWSSPISGPRRYEYVEERERWVYTRVIEEGDGKECAEVAENDDDTLGSILTQELKELYGWDLDVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y181</accession>
    <name>A0AAD8Y181_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011511</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y181"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="36"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="224"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="263"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="36"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="229"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="486" mass="54460" checksum="1E55C2F57EF89303" modified="2024-05-29" version="1">MHYTSTNIKMAPNDNNNNTTASSLDLLASTSKTMINSLLPTRTTSNLPTSEEGRNTKISPTNSSEQDCPREGISTSNSSSYHSIRYAHLPSTENYTTIKSKHRQGRRCYRLNLERPFNIHCEQSPLEYGDIFAPWKKSVRPPLEGPVEYCPPRHLGGQGEVWRQLLSYSGSESRIVKEVNTGWRTLTEKEVEQVKRLGECNERGEYGFVTYDLSHVKKHSQCASGEAITPSTSMDSLSSNEEESTPQSETQKANDTARLFRRSELSLRDAAEAKARLDAAEKERLKAERKDREQQELAALKSIKGPKGVTRRMSKKASLNGKKMMRKLSSSLGGSSSSVTHGGIYEGGGRTRRKLVSTQAGMIDKAKDLVDDESDDEYDGEKYDDTKKIANMSLFIVGEYDVLNDLCLDGGLRLKKTKDLSDLELLLQNEPCPPPNRWVRKTGWGKCNPSSMYAECPPEDFDWESYLKKDGPVKVNPVPRPVMQKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1F8</accession>
    <name>A0AAD8Y1F8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011153</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1F8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="200" mass="22249" checksum="3EE2AB721154E7CD" modified="2024-05-29" version="1" fragment="single">YITASQLFSQRANSENDDAVLAHARSCYSYYFIAKMSVDNAGAPPMKWCCVNKHKNEPLTILFHCTWSGKEYPVPAKAEHENVENNYYDEPNGDDEGILLGSTTLKDSVKSFKAREPTLFLMEECGGTEMHCGNNTVCGLEWEMTMVCHLVYDQPEDLIPRVTLDDGRNAVVITLGTKGDPLNKKPSVVSRCLAKGDVYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1J2</accession>
    <name>A0AAD8Y1J2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011764</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1J2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="95" mass="11051" checksum="22106EC9EB172440" modified="2024-05-29" version="1">MKELDDGIDTEEQKMKGLEEEIDAIRTRIRERSETKTQLPPSSRPVVQYGSYYRMQQQQKQAAAPSEPADPSTLKRKINHMLSEYKRASVNVWIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3G9</accession>
    <name>A0AAD8Y3G9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010528</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3G9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="184" mass="20285" checksum="6FA7650CE4FC993F" modified="2024-05-29" version="1">MPKLSIISGGATSFGYKDGKSQLPSSSPTTSDTSHNSDNDEDRNLHSFNTAFRRIKWLHATHYSAIIMPSIQRQRTIRNRQRTYPAVIGWPGKYKEGGGNIQDDASGPRVVILGTEFQIQKASPTQLQKLDVAHWPTWTTSDKSKWGVGNLVVDKEMPYGVASYVLSGKLEIIPQSTGVPKLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3L5</accession>
    <name>A0AAD8Y3L5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_010535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3L5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1738505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="81" mass="8497" checksum="9BAA8C7DD454657B" modified="2024-05-29" version="1">MSIISASSTYMDRYLFILALIPTGASAFYKGAVPHQHQEGPTIPAAAEGLLDNPAVLSDPNINPARKCGFCFGTNCPVSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3Q9</accession>
    <name>A0AAD8Y3Q9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3Q9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="200" mass="22503" checksum="A0B6CF1FF8EC6252" modified="2024-05-29" version="1" fragment="single">MVPPVTTTANHHRRRRAVIVCSLLSWTCAVSTAFSPTHHLPSSVHTSSSSPTPHSPTPSNHHHSTTIRSTTHLHSLFTSSKKKKNSPLEDEPWKKDDSYWDQLQAASKDPEQFEKFIEETMAKKNKVSSSSTTSSSTSSLSSAYDAAKQQEEEKPKKKKGAYVPIEQWDATRSKDDMTKEERLQWECQRGGNGVRQNEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4H7</accession>
    <name>A0AAD8Y4H7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Trafficking protein particle complex subunit 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010301</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4H7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990071">
        <property type="term" value="C:TRAPPII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034498">
        <property type="term" value="P:early endosome to Golgi transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045126">
        <property type="entry name" value="TRAPPC10/Trs130"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056913">
        <property type="entry name" value="TRAPPC10/Trs130_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13251">
        <property type="entry name" value="EPILEPSY HOLOPROSENCEPHALY CANDIDATE 1/TMEM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13251:SF3">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23036">
        <property type="entry name" value="TRAPPC10_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TRAPPC10/Trs130 N-terminal" evidence="2">
        <location>
            <begin position="395"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1196" mass="131744" checksum="86ED3C49DF20098A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5D7</accession>
    <name>A0AAD8Y5D7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pho88 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_009561</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5D7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045047">
        <property type="term" value="P:protein targeting to ER"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012098">
        <property type="entry name" value="SND3_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28112">
        <property type="entry name" value="SRP-INDEPENDENT TARGETING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28112:SF1">
        <property type="entry name" value="SRP-INDEPENDENT TARGETING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10032">
        <property type="entry name" value="Pho88"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042164642" evidence="3">
        <location>
            <begin position="22"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="363"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1739802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="466" mass="51273" checksum="25CAFBD26648A421" modified="2024-05-29" version="1">MMHRPIMATSLLWIAAATLLALPSSINNNVATAEILTHHVGGANSASLHKTWGKFIQRQSLTTTLTSKTESTSVAALTNTNNNVSRRTSRLATLPCFVRRLPTQQQSSLHKSTRQSMVDVEWSLATGQIITKIRGGATDDDDDSTTDGEHTTDGESSDGEEYDDEYDEEYESDYDEESDEEEEEEDNIVSSLTSSSLKSSLRSKSTSTEDTQIAQYDEVLAPPAMQQLVISLGVMFLSQRIDILDAKTVRIARFAFVAYIVTMQLFLLYVRFRAKAINDRTEITLSNPLASLVQGAAGGAMGGAAGGGGGNFMVKALADQMLSSTTTIYEYDVSQAKKMNSGLLMPMVFLYFLHFRMKQVQPLLMQTATGVMNMVYSPLFQVYVLGRNLERPFKSPGGSMMDALQTEEEGDESESSSEQGVEEVEDDDADVDDEEEEAEDSEEEEESDAGEEESDGDESEYDTDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5M4</accession>
    <name>A0AAD8Y5M4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-CH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_009028</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5M4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-CH-type" evidence="4">
        <location>
            <begin position="17"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1740078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="428" mass="48053" checksum="1217AE975A8FA8BC" modified="2024-05-29" version="1">MTHPMSVEVNMCTNNAADGSSSSCCWLCLGDGPDASGMPLTRNCSCRGSSGFAHLSCIIRYAEIDGRNSFQSTGNIGAAFQECPNCKQEFQNDLRYHLERARVSFIEKEFSNDHMVHLRALIHRMRVLDVKSDVDKAEGDQICFKMISIIDEMKGHPSMQRDWKSGGFMKMEAVVLYVVGLFHMNIGSEENLREALDYFRRAVDLFTLLGDEINMMTAKKNISKVEAKLHGVEVYYDEGSNLKFSQKQYNYWFEKLGEHHPITIRRGELYAHALYCSNQGVAAERLLTKLAAISRQVHGPTHNSTLSAASALKDIKERRVFIDSRKEWFHALRYENDGLSCVVKGPVVESAHGYEDHMMTLSLPITDVLPAPGTPVVCQGLSERAHLNGKIGDTQGFNGGQFEVHFEEAGLEPAIIKHENLRIVFELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y684</accession>
    <name>A0AAD8Y684_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Short-chain specific acyl-CoA dehydrogenase, mitochondrial</fullName>
            <ecNumber evidence="4">1.3.8.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Butyryl-CoA dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">QTG54_008518</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Short-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, short-chain specific acyl-CoA dehydrogenase acts specifically on acyl-CoAs with saturated 4 to 6 carbons long primary chains.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>butanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:24004"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57332"/>
            <dbReference type="ChEBI" id="CHEBI:57371"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="1.3.8.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:24005"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>hexanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-hexenoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:43464"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:62077"/>
            <dbReference type="ChEBI" id="CHEBI:62620"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:43465"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>pentanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-pentenoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:43456"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57389"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:86160"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:43457"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; mitochondrial fatty acid beta-oxidation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.8.1" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y684"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016937">
        <property type="term" value="F:short-chain fatty acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046359">
        <property type="term" value="P:butyrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01158">
        <property type="entry name" value="SCAD_SBCAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.540.10:FF:000002">
        <property type="entry name" value="Acyl-CoA dehydrogenase FadE19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000004">
        <property type="entry name" value="Acyl-CoA dehydrogenase FadE25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000001">
        <property type="entry name" value="Acyl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884:SF12">
        <property type="entry name" value="ISOVALERYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 14" id="KW-0274">FAD</keyword>
    <keyword evidence="5 14" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 14 18" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="17">
        <location>
            <begin position="66"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="16">
        <location>
            <begin position="188"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="15">
        <location>
            <begin position="295"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00045387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00050758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1740423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="451" mass="48841" checksum="275721EE56692C67" modified="2024-05-29" version="1">MRLSLARSLHSKLGAPSTATRVAIASSSNYSTLLPSQNRGNTPAQHQNINIPSSSRKYTTYSQLPSEHQMVYEMCRKFAEEELMPNAGKWDQKHEFPTEAVDKLAELGLMGINCSSDHNGSELDALSYAIAMEEISRGCASVGVIMSAHNSLYLYPIDAFGSDDLKERYISPYTGHERDENGRLNIGCFGLSEPGNGSDAGAASTTAKEDGDEWIINGTKAWITNAHEASAAIVFATTDKSMKHKGISAFVVPMNAPGFSLGAKEDKLGIRASSTSNLIMENVRIPKSNLIGQPGEGFKIAMQTLDGGRIGVAGQALGIASASIDCAVKYALERNAFGKPIAQLQSIQNKISQMTVARDSARLLTWRAAQMKDDGEKYTREAAMAKLAASEAATMCAHQAIQILGGMGYVTEMPAERHYRDARITEIYEGTSEIQHLVIAGDVLKEYKQLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6Q5</accession>
    <name>A0AAD8Y6Q5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-CH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_009075</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6Q5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-CH-type" evidence="4">
        <location>
            <begin position="14"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1740125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="439" mass="48817" checksum="ED0440D0DBA16304" modified="2024-05-29" version="1">MSSSSRSTSKTSTSMPPDGASCWLCLEDGPDDSGAPLVRDCSCRGHSGFAHLPCLVKYGNQMAEQALRKAEATGTVANMVDIFYKCPNCKQDYQNGILVEMKKANITFHKEKLMQPGADKISLTIESAELENRLRNINGRNKNERDEGLKIVTKLLSISRELKQCDCLPIPMGVGMDEHIGDFFESCSDDHSLKRAKAFYEKARDAIVAWGGEYKLDRKGVDYKIKRVEAKLGGGSGNDRQVGKAAAVKLLQERYDYCVALGDDNDTITAGINLASVLHTSDHAIEAERLLDKLIVSSRRVHGSNHNQTQKCLSLLQSVKERWVILHSEQQWFEALKYKKNGKKCVIQGPIKEPRVTDEEKTITVPSGEVRPYKGTPVMFHGLKKAAHLNGKIGDVREYNTSTDRYEVHLEDKGLKPVLAKHGNLKVLFDLPNPTKESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6W1</accession>
    <name>A0AAD8Y6W1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6W1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1739801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="328" mass="36324" checksum="AB6DE7C5D5C1CBBF" modified="2024-05-29" version="1">MEKELNAESLEVKLPVYKAITSMRPKATLKQLKSKRRIVALRGNKDQFTEVMDMLCSLRRRFVQSQTLLVLVPTDGSTKEEWGWDDKQMGDSLWLADATNIGQFLDYFQELLGSDERVSNDNELAWFALNFKGRSIASGLGEAPKILELMGQQLQPMELIDDTDAAVVPADMPVANEILECQSKFYNVLTSTGDLEAMKAIFTDGKMQEVNEVIGAGGRIDGWFECLKPDARPANMVIADQDIFVSSPTLAYSTCVEFPPNAGIDGATLLASQRWVRETANDEWKLELHQTIPWAAGTRAGGTLRCDCRGCVALTSSQEKRTFGGLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y747</accession>
    <name>A0AAD8Y747_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y747"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="347" mass="39178" checksum="14E09384BAF46EA0" modified="2024-05-29" version="1">MSTIRILSNVGNAFFLASGCWGDLLLIRVFLTFAYVCLLAIHFVKRSTDYEDYVWGFGTLYLHGSSAVRLFHDEGEVKMDEKKEQEALWRYFYRRSGISRLLFKSHVAKCFELIDAKAGEALDTSTFFYIILDGSVDIKTTVTGSTRDYTLVSGESFDIKHLQPLFRVRSAYMKKSQRMSPFVHQDIVATVAVDAKLFRCSHESMHGLCNTPATKDASQGLLIATLSDMAEREYMKYPPLPNDSVTKDMLDEENQLPKGIYATFKSTRSAVFAPLEDFEQPARFLAGSGSFKGIHNHILHTLKVAFLLPWPFMAWLPGLRQIGSLPVPPAASDVDEKTIPEERSRES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y756</accession>
    <name>A0AAD8Y756_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lactonase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008228</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cycloisomerase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y756"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050282">
        <property type="entry name" value="Cycloisomerase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011048">
        <property type="entry name" value="Haem_d1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344:SF1">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51004">
        <property type="entry name" value="C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="424" mass="46737" checksum="B56C6B0D7CAFF31F" modified="2024-05-29" version="1">MQSKTPCSLQINDLFHIIIHSNGSLQQLFQTNSTRCSSVLTTDASSDGHSPGIRSLASHADDDDDNYVDQQLFFVTSYSDFDKLAHGPRGHAGKYTLRVYKFFANDGALVLLHINGEAANVINPAFSRFHPFLNVVYTCTEDIEENGKILAYQIESDGSLLQIGEVDAGGTSTCYLTIDRDQRNLIAVNYWDSSLVVIPLSKTTGEFKGPIHSVYDPRQGKAMQAAAKKHGGVNHSNNDDSTIAQRQKDPHSHALVLDPFEGCVAYVPDLGKDLVREFWYDKECGRIGCELNTLPSGLSTGKADGPRYFEFHPKFNIAYIVNELSSTVAVFSIDRELLSEIARAAKLKKPMDAFKGRSTLKLIQSIKTVPSAFPTKLNTCGRIACTNLVDLSLFRIEAMNHSQYSVSSNPMEAAAKHAKVLLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y800</accession>
    <name>A0AAD8Y800_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Translation factor GUF1 homolog, mitochondrial</fullName>
            <ecNumber evidence="7">3.6.5.n1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Elongation factor 4 homolog</fullName>
            <shortName evidence="7">EF-4</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">GTPase GUF1 homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Ribosomal back-translocase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_008772</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.n1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion inner membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
            <orientation evidence="7">Matrix side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the GTP-binding elongation factor family. LepA subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.n1" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y800"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03699">
        <property type="entry name" value="EF4_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16260">
        <property type="entry name" value="EF4_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01890">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03709">
        <property type="entry name" value="lepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000078">
        <property type="entry name" value="Elongation factor 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000015">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2570:FF:000001">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000004">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2570">
        <property type="entry name" value="Elongation factor 4, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00071">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006297">
        <property type="entry name" value="EF-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038363">
        <property type="entry name" value="LepA_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013842">
        <property type="entry name" value="LepA_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035654">
        <property type="entry name" value="LepA_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01393">
        <property type="entry name" value="lepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512:SF4">
        <property type="entry name" value="TRANSLATION FACTOR GUF1 HOMOLOG, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512">
        <property type="entry name" value="TRANSLATION FACTOR GUF1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06421">
        <property type="entry name" value="LepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041927191" description="Translation factor GUF1 homolog, mitochondrial" evidence="8">
        <location>
            <begin position="21"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="62"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="71"/>
            <end position="78"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="138"/>
            <end position="142"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="192"/>
            <end position="195"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1740677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="683" mass="75420" checksum="BD45106A556A58D7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8Z8</accession>
    <name>A0AAD8Y8Z8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Atg6 BARA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007707</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the beclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8Z8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034271">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034272">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043548">
        <property type="term" value="F:phosphatidylinositol 3-kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045324">
        <property type="term" value="P:late endosome to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.40">
        <property type="entry name" value="Autophagy protein 6/Beclin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007243">
        <property type="entry name" value="Atg6/Beclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038274">
        <property type="entry name" value="Atg6/Beclin_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040455">
        <property type="entry name" value="Atg6_BARA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12768">
        <property type="entry name" value="BECLIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12768:SF4">
        <property type="entry name" value="BECLIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04111">
        <property type="entry name" value="APG6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Atg6 BARA" evidence="2">
        <location>
            <begin position="610"/>
            <end position="775"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="786" mass="85451" checksum="7E3CAB80F3B9BE6A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9G4</accession>
    <name>A0AAD8Y9G4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">shikimate kinase</fullName>
            <ecNumber evidence="3">2.7.1.71</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">QTG54_007953</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>shikimate + ATP = 3-phosphoshikimate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13121"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.71"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the shikimate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.71" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9G4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004765">
        <property type="term" value="F:shikimate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00464">
        <property type="entry name" value="SK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00109">
        <property type="entry name" value="Shikimate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031322">
        <property type="entry name" value="Shikimate/glucono_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000623">
        <property type="entry name" value="Shikimate_kinase/TSH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023000">
        <property type="entry name" value="Shikimate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21087">
        <property type="entry name" value="SHIKIMATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21087:SF16">
        <property type="entry name" value="SHIKIMATE KINASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01202">
        <property type="entry name" value="SKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01100">
        <property type="entry name" value="SHIKIMTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01128">
        <property type="entry name" value="SHIKIMATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0732">Signal</keyword>
    <keyword evidence="5 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="8 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042133661" description="shikimate kinase" evidence="16">
        <location>
            <begin position="21"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="17">
        <location>
            <begin position="310"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="45"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1741475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="533" mass="59541" checksum="0E1F07A2A05927DF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9K7</accession>
    <name>A0AAD8Y9K7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_007764</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9K7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1741286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="86" mass="9781" checksum="101E89BB81479070" modified="2024-05-29" version="1">MSSWTIIGQTFPQQAVRKTISFDTTKWTLQTVSKNRQQTGTDYKGGNSYWVNKEVWQCNGISSLPSDKYTEEVDELELAIPFGNAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAT1</accession>
    <name>A0AAD8YAT1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAT1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010530">
        <property type="entry name" value="B12D"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06522">
        <property type="entry name" value="B12D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="72" mass="8040" checksum="7A990D58F4459439" modified="2024-05-29" version="1">MAAESRAHLYKDIPTNWDQLKNNIWLSDAGALPVIFVLTFACGLSATFIGYNCVANPDVRITTSKRQQLIRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YB21</accession>
    <name>A0AAD8YB21_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YB21"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="607" mass="67997" checksum="933DC31C979F42F5" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBP5</accession>
    <name>A0AAD8YBP5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">BTB/POZ and MATH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006135</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBP5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14733">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00121">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002083">
        <property type="entry name" value="MATH/TRAF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="189"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="SAP" evidence="3">
        <location>
            <begin position="385"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1743514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="419" mass="47034" checksum="471E27BB5547936A" modified="2024-05-29" version="1">MADDNSMSGRSSSSEDEDQPTSVRTKIKKEPCQPKARKFSVTFENFRDLPAVKNRGVQSSKFACFGHDWRLQLFPGGYSDYPTPPKGAVGVCVERSNQTGKWPNVKFLFELKSPDGNISLQTSGDPSSYKCYSNTSNICALTTRPDIKHRFLDDKRALTISVVMEINEFVPKNPLAATMLKLFGDEESSDVIFEITKKEEKTKKRRREMASSSVQFHAHRFILEHTSSELAALCESSPEGGMNSPIIINDIKAEVFRGLLYYIYGGEIRQESLMASGKEVIDAADKYGVVNLKLEAEVWYVHSTRITTDNVIDNLLYADAKNLALLKEAVMDYIVKNKKKVMKRVSFKEVPGDIYKDLLAAVSRVLDDSDEDNSDEEEDEEKDDYASMGIGALRQKLDQRGIDIDGSRDTLIAALKKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBP9</accession>
    <name>A0AAD8YBP9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DNA polymerase</fullName>
            <ecNumber evidence="14">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">QTG54_005828</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="14"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBP9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008296">
        <property type="term" value="F:3'-5'-DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006287">
        <property type="term" value="P:base-excision repair, gap-filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045004">
        <property type="term" value="P:DNA replication proofreading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05777">
        <property type="entry name" value="DNA_polB_delta_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.690:FF:000001">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000004">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.690">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050240">
        <property type="entry name" value="DNA_pol_type-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322">
        <property type="entry name" value="DNA POLYMERASE CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322:SF23">
        <property type="entry name" value="DNA POLYMERASE DELTA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 14" id="KW-0235">DNA replication</keyword>
    <keyword evidence="11 14" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 14" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="9" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="8 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase family B exonuclease" evidence="16">
        <location>
            <begin position="52"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="15">
        <location>
            <begin position="360"/>
            <end position="704"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1743207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="705" mass="79539" checksum="0FC61B7DF26531C2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBX1</accession>
    <name>A0AAD8YBX1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inorganic phosphate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_005933</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBX1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="552"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="576"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="611"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="643"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="208"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="323"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="347"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1743312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="671" mass="72577" checksum="4EFC8669D4BEEF8C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD57</accession>
    <name>A0AAD8YD57_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005971</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD57"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23669">
        <property type="entry name" value="GH55_SacteLam55A-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043534">
        <property type="entry name" value="EBDG/EBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059186">
        <property type="entry name" value="SACTE_4363"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43536">
        <property type="entry name" value="MANNOSYLGLYCOPROTEIN ENDO-BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43536:SF1">
        <property type="entry name" value="MANNOSYLGLYCOPROTEIN ENDO-BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="737" mass="80730" checksum="18338B494CBA7CF4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDA9</accession>
    <name>A0AAD8YDA9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">2OG-Fe(II) oxygenase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004902</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDA9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33099">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33099:SF7">
        <property type="entry name" value="MYND-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="560" mass="61786" checksum="5878DBF426E35D4F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDG3</accession>
    <name>A0AAD8YDG3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Serine/threonine-protein kinase</fullName>
            <ecNumber evidence="6">2.7.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_006106</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDG3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF288">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="48"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1743485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="440" mass="50017" checksum="71C88E1780F92393" modified="2024-05-29" version="1">MRILKVDSSIHNKRIKASDLARRSSDDFCETYGHSPLESVAPFQRGEIILGRRVGAGSFSSVYDIQDYNLSAKQSDKYTDEHEQAKKREATAKSVMHGTKYVMKCLKDKLEESDADEYLFHCAAQDIAFEAEMLAALSHPNIIKLHGVVDSHHDAFLDGASEFFIILERLDCTLTDKIEGWAKNSFNPSRSFKSLRSSLSSRALALDKAETEKGAPTTTSVDEGRSLVCRLRVAASLADAMEYLHAQNIVYRDLKPDNVGFDRHGNLKLFDFGLARFMPRHGDACEDVFEMTGLGTPRYTSPEVLFHQPYNLKADVYSFCVVLWEIMCLKKPFGKYNQRKDLEREFSRLDSKPLSINRRWPQPIQDIFRSGLSRDLWARPVMSDMCKVLTECTSTARDLQKFRSLGTFFFEVCCKKTPCDKYSVSISRAEHANSHQPIII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YE82</accession>
    <name>A0AAD8YE82_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein-serine/threonine phosphatase, PP2C family</fullName>
            <ecNumber evidence="6">3.1.3.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_004185</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YE82"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="5">
        <location>
            <begin position="1"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1744894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="190" mass="21238" checksum="A07E320F97D01CB4" modified="2024-05-29" version="1">MEDQINQDRAFVLSPFMYRNIMKEDSKVRPVARLLGVFDGHARLGEKVSEYVVKTLPALLGSKLVAKEELSNQEIGKILQDTFVEIDASSPADPSGGCTASIVLQIDSNIYIANAGDSRSFVAVHIIDPISKAETTHIIYGTREDSLIFLSKGYESKQWVETSTFHQVVKELPECCIRTLLLEYKWIGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEF3</accession>
    <name>A0AAD8YEF3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Eukaryotic translation initiation factor 5B</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Translation initiation factor IF-2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_005313</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEF3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03703">
        <property type="entry name" value="aeIF5B_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16266">
        <property type="entry name" value="IF2_aeIF5B_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01887">
        <property type="entry name" value="IF2_eIF5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000013">
        <property type="entry name" value="eukaryotic translation initiation factor 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000026">
        <property type="entry name" value="Eukaryotic translation initiation factor 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000112">
        <property type="entry name" value="Eukaryotic translation initiation factor 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.980">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="entry name" value="Translation initiation factor IF- 2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029459">
        <property type="entry name" value="EFTU-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017856">
        <property type="entry name" value="Integrase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048300">
        <property type="entry name" value="TACO1_YebC-like_2nd/3rd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049083">
        <property type="entry name" value="TACO1_YebC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026564">
        <property type="entry name" value="Transcrip_reg_TACO1-like_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029072">
        <property type="entry name" value="YebC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381:SF4">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14578">
        <property type="entry name" value="GTP_EFTU_D4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20772">
        <property type="entry name" value="TACO1_YebC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01709">
        <property type="entry name" value="Transcrip_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="Initiation factor IF2/eIF5b, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75625">
        <property type="entry name" value="YebC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 12" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="11">
        <location>
            <begin position="374"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="74"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1083"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="303"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="103"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="203"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="237"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1086"/>
            <end position="1095"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1743716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1154" mass="128903" checksum="BE12C59877C3FFB3" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEL9</accession>
    <name>A0AAD8YEL9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_006191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEL9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1743570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="91" mass="10444" checksum="7E8540BB3DD855B3" modified="2024-05-29" version="1">MSNKNVAGCKIEYIKEVDCMLAIDTCLRYLRAHALKDIEAGAELYVDYGSSWFMSREGHFQLVPLKSSYEKALAFLQQYGKMIVGKVQMIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFL1</accession>
    <name>A0AAD8YFL1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WRKY19-like zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005677</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFL1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056866">
        <property type="entry name" value="Znf_WRKY19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24906">
        <property type="entry name" value="Zf_WRKY19"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="279"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="335" mass="35611" checksum="F5CC6BDBA9F3C1B4" modified="2024-05-29" version="1">MPTQLNYVKGEWLDREEELLLRRAELLSEKKDLVTKKDDFAARMSAGPPPSVHPKSAAVVGSQVPKDLVTAADGLLCLGGGNAGLQQPADIHVTQIVDEKSSTAAASKNITKKRQLSSKEADDDDDDDPSSKKQKKSYVKLCSVEGCAKLVQSKGVCIGHGAKLKRCSSEGCPNRAVKGGVCKRHGAVVERKKCTAADCTNLAVKAGACLKHGAKNRSSEPKKTPANKKGRKVKVPLLCKPVTPGTQPKVKRCTIEGCNRQAKQGGVCVKHGAKGGSSKCSHVNCPKYAQRGGVCIEHGAVFVRKRCSVKGCDNGVKKRGLCRRHGAYAGDTPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YH85</accession>
    <name>A0AAD8YH85_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002679</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YH85"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="143" mass="15995" checksum="2F3489311983B6DE" modified="2024-05-29" version="1" fragment="single">HIDTATGINRNNGSDPNAAGREKVIQTQLHSETRAVLCRLQGIDRSLYSEIDPLHLPEVLSLIAQRHGEGELYAAVLSSIMTLFSTMNREKCIQQERDYHAAKAAEHIAKVEELDKELATIKEAAAMRSQDNVCSQSNKRRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIT2</accession>
    <name>A0AAD8YIT2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 6">Inositol-pentakisphosphate 2-kinase</fullName>
            <ecNumber evidence="1 6">2.7.1.158</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_002921</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP = 1D-myo-inositol hexakisphosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20313"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57733"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.158"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="6">The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.158" evidence="1 6"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIT2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035299">
        <property type="term" value="F:inositol-1,3,4,5,6-pentakisphosphate 2-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032958">
        <property type="term" value="P:inositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.110">
        <property type="entry name" value="Inositol-pentakisphosphate 2-kinase, N-lobe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009286">
        <property type="entry name" value="Ins_P5_2-kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043001">
        <property type="entry name" value="IP5_2-K_N_lobe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14456">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14456:SF2">
        <property type="entry name" value="INOSITOL-PENTAKISPHOSPHATE 2-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06090">
        <property type="entry name" value="Ins_P5_2-kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1746314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="555" mass="63067" checksum="484ACE06B8703DBA" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKG4</accession>
    <name>A0AAD8YKG4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000193</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKG4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042249814" evidence="2">
        <location>
            <begin position="20"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="384" mass="41976" checksum="3CC6BF68EAB01776" modified="2024-05-29" version="1">MRSLHLLCLVSAGPTLGAAFSFPPGVNKIAQSSPAAASCRLSPSQHHNRHDFHAISSIPYQKQRCKETRLQAATLSAADNKLFPSRNERGFFELKTLIRVLFPAIISGAIAYATLPALNNQIATFVLKVTDPGKISMLGDAVQSFISLVGLLYSILVGQVFGFLYSQQEALYLALFDEVTEAKSLLEQVALVSQGRTMYSTCLNSIARYVKQDLLEGMESFDGSITPSLLVSARPSDDPLEAILYLTSVGIPGHVYDTVRSLRQARSRRLGALQRKVPVIHLIMLWLLGIIMVGSFPVFLGVSEAAASMGGLITRSNMTVQSGLFGVATFSVVMCKSVLIELWRTKGGAYNVDKTLKVMVSGLKKELDERMDEAKKIMKRSKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKP0</accession>
    <name>A0AAD8YKP0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sulfhydryl oxidase</fullName>
            <ecNumber evidence="7">1.8.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_001746</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2</text>
            <dbReference type="Rhea" id="RHEA:17357"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:16520"/>
            <dbReference type="ChEBI" id="CHEBI:17412"/>
            <dbReference type="EC" id="1.8.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.3.2" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKP0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016971">
        <property type="term" value="F:flavin-dependent sulfhydryl oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.310">
        <property type="entry name" value="ERV/ALR sulfhydryl oxidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036774">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017905">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039798">
        <property type="entry name" value="Sulfhydryl_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22897">
        <property type="entry name" value="QUIESCIN Q6-RELATED SULFHYDRYL OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22897:SF8">
        <property type="entry name" value="SULFHYDRYL OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04777">
        <property type="entry name" value="Evr1_Alr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69000">
        <property type="entry name" value="FAD-dependent thiol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51324">
        <property type="entry name" value="ERV_ALR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 7" id="KW-0274">FAD</keyword>
    <keyword evidence="2 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 7 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="ERV/ALR sulfhydryl oxidase" evidence="9">
        <location>
            <begin position="374"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="601"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="601"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="639"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="661"/>
            <end position="673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU371123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1747783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="690" mass="78846" checksum="E65AE6F7AD3F88F4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLR7</accession>
    <name>A0AAD8YLR7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_001414</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLR7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="36" mass="4435" checksum="8247FA359D3025C4" modified="2024-05-29" version="1">MFAWPIWLDDFHPTDKYNTYFRPTSGSRWYHTGNII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMN5</accession>
    <name>A0AAD8YMN5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMN5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="329" mass="36695" checksum="6B92DFC068E57029" modified="2024-05-29" version="1">MIDSDNKSSSSSAHKIACTSGPRRGKVLVVPASAAVKKEQHVVTDEPPPPPPPSTNSCHVDSETSSAPTVEDYANLFFGSDDDTSLTGNSIQSLAMTHHHQWEPEPHLPPTRPTTSSSIVPLLPPTTHCHRRKRRRVSFTTTTPTIHTLHTVPTSSTMTPLEKSTSWLQHSDIETLKSSAQSTIQTVRNRVSSNAREYKHRHKFRALMVTIEQETDSSIRGLEHKVYRRKETRRMLIQDVIECQHHIKGLARFGHVMSSDEKRRLLANASLQKSLGCVKKALLDANDDYKEVYGQKKLFNGFMERPPVFKIRRVSSGAVTDDGAAKKSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YP54</accession>
    <name>A0AAD8YP54_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YP54"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17039">
        <property type="entry name" value="Ubl_ubiquitin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="3"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="125" mass="12748" checksum="BD77A610034C2F64" modified="2024-05-29" version="1">MSITLYLSLTSSPSSPRVSINVPLEATGADLRKLSSEATSIPLATMKLIYRGRVIADNETGEVLKEFKLENDMVIHVMGKPAAAAAEPAPSSSTATTTATGASVTLPTAAAAALLPHDASPLASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3Y1</accession>
    <name>A0AAD9D3Y1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016362</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000055">
        <property type="protein sequence ID" value="KAK1733031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3Y1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12087">
        <property type="entry name" value="TM_EGFR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="478"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="505"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="818"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="889"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1057"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1136"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="447"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="550"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="615"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="653"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="690"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="705"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="767"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="784"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="912"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="945"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1082"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1093"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1205"/>
            <end position="1232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1239" mass="131896" checksum="58F9CDE498F568EB" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D446</accession>
    <name>A0AAD9D446_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Spermidine/spermine synthase family protein</fullName>
            <ecNumber evidence="8">2.5.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_016923</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000068">
        <property type="protein sequence ID" value="KAK1732388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010487">
        <property type="term" value="F:thermospermine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006596">
        <property type="term" value="P:polyamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43317">
        <property type="entry name" value="THERMOSPERMINE SYNTHASE ACAULIS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43317:SF1">
        <property type="entry name" value="THERMOSPERMINE SYNTHASE ACAULIS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01564">
        <property type="entry name" value="Spermine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 4" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="PABS" evidence="7">
        <location>
            <begin position="179"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1100"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1360"/>
            <end position="1379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1362"/>
            <end position="1379"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1732388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1461" mass="164159" checksum="B4E1D3E1D2EF7326" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D452</accession>
    <name>A0AAD9D452_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_016938</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000068">
        <property type="protein sequence ID" value="KAK1732403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D452"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1732403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="184" mass="20944" checksum="8B44BAE349247B1D" modified="2024-05-29" version="1">MDMTLVIQDNGIITDLFEKKMALYLYIPPHSAHSPGQLTGLVMGQVLRIFSLCSRTVDKQMHTYQELLVLVRCGYSHSDLLPLLEKAATNSEAFIGKSEEDKAREKCQKDEDSSKRIFLHLKYHPNDNDPKSSAIQKAFRESIMHPKGDQPFTELENERGHKIPLDRLTVCYSKHSNLGSLNDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4D2</accession>
    <name>A0AAD9D4D2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">C2HC-type zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015714</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000047">
        <property type="protein sequence ID" value="KAK1733541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4D2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13913">
        <property type="entry name" value="zf-C2HC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="407"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="165"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="419"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="446" mass="50378" checksum="B5675CCC901853D2" modified="2024-05-29" version="1">MESDWSNRRKSAMNRARELRSKIKEMHSDNADDASNTVMSSREIQRQRRSRQLEETKRLLDQFADAEVEVDEQRRVSSNDSVRSGKNSLYGNYGSIEAQVASSQELLSRSHRRDKYSADPPAESGSSQMRIQAESRTVRETSHRQPGQFGRGRGRGRIGSGGGATATSSRQVGSSLQSSKPFPRDYTAVEMPSAQQGQVRNKFSASNENTAKPQCFYLRDHRVPEHKDGECDKLVVLRQRLAARRRMRELALEGGTKEQKIEPSSMHGMEKPHSHRVDNEAVPHEHSARQHTNQFSHKDVDDANRSHRSSHNNDNATQLNISTGSAGSIASEKSVVDIELVQCDCCGRSFAPKVYEKHFDSSGQPKCVNDKNKKRPVFNSAKARIANNSNLNQDEQRQVLQMNKKVSKDLAKKKNGKGRTMEKIRRSSKWRDESRAFRDAMKASKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4Z2</accession>
    <name>A0AAD9D4Z2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_015028</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000040">
        <property type="protein sequence ID" value="KAK1734261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004694">
        <property type="term" value="F:eukaryotic translation initiation factor 2alpha kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23823">
        <property type="entry name" value="RWD_GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF136">
        <property type="entry name" value="EIF-2-ALPHA KINASE GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00591">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-0652">Protein synthesis inhibitor</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RWD" evidence="14">
        <location>
            <begin position="47"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="329"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="419"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="221"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="430"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="469"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="486"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="359"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1734261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1725" mass="192194" checksum="135758EA68EA2363" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5N5</accession>
    <name>A0AAD9D5N5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chalcone isomerase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014456</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5N5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016872">
        <property type="term" value="F:intramolecular lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016088">
        <property type="entry name" value="Chalcone_isomerase_3-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036298">
        <property type="entry name" value="Chalcone_isomerase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47698">
        <property type="entry name" value="FATTY-ACID-BINDING PROTEIN 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47698:SF2">
        <property type="entry name" value="FATTY-ACID-BINDING PROTEIN 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54626">
        <property type="entry name" value="Chalcone isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="284" mass="30370" checksum="887CFB4C37D1CEED" modified="2024-05-29" version="1">MMNSPRLLISRQSHRLFCRSPPSSSSVTSSAPPRSTAHRIVTRPSSSSSSNNSSAAAFSSAQPTAAGTAILLTAAALLFTATTNDAKNNAASLCSVAPRLGAEPTMLSPATEPKTGILFPRLCNGMTFVGCGVRVKYGFVKVYAVGTYMDPLAMSVIKDQSKPQLQKALLDPNYPRTIRIVMNRNLSIEKYTAAIIEALEPRMKGQDLESLEEFKKLNPPVDLIQGAEMEMTVRGDTLLYKNAVGGIGQIRSGVFTSALCDVFYGAEAVSPGHLEDVLKGVKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5P7</accession>
    <name>A0AAD9D5P7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015476</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5P7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="574" mass="61754" checksum="064FABB315F9918D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5W2</accession>
    <name>A0AAD9D5W2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbon-nitrogen hydrolase family protein</fullName>
            <ecNumber evidence="4">3.5.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_015147</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.-.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5W2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07197">
        <property type="entry name" value="nitrilase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050345">
        <property type="entry name" value="Aliph_Amidase/BUP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43674:SF16">
        <property type="entry name" value="CARBON-NITROGEN FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G02350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43674">
        <property type="entry name" value="NITRILASE C965.09-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="3">
        <location>
            <begin position="30"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="347"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="347"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="367"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1734144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="376" mass="41090" checksum="7E6728794D854CCD" modified="2024-05-29" version="1">MMTSRKTSSITKIHSTKDIADEQSNVVERVRAAVFQAPVSQSENPLEILTEVADSLRVASLHGVDVVVYPELYLSGPNNSKALDRESYELNIVGNMCGELNVACIIGYVEAVHESELKKNNDDSSGDGKEYAYSSIAAFHADGSRAGNYRSVSASKFGGKECREGSPFVEFIPTTLKLPNNREKSEQSSGHEREIKVGMMCGNDILKPVHSLHLVRCGAQILLAPCSFKNNNNDLRALKYVTATRAIENSVPFLFANRESATTTDDVKDKDVFIGSSAIISQDGEYLVCGPEEEGGDMPSDSGYLIPCKDGVIYAADIEVDTSSTSSVIQQSIEQWDLHPLIPDVFGDKRSKEKTRESNGFGNYTGKKNKGKKIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5W9</accession>
    <name>A0AAD9D5W9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5W9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="141" mass="16408" checksum="93F6DD783636DB97" modified="2024-05-29" version="1">MRETVLWIQFFFGIVWATAWLISYSLGYYKQWASDPQIIADLTLAYWKVSIINGVGIFVALVVLFGAIYYKPALVFLGAIYTIVEAILTPIYIYPVVKDFYTSSWMYIVWPIIYGMLIVYPHVVFTYELKTGVWENPNFSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6H2</accession>
    <name>A0AAD9D6H2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cyclin-dependent kinase 2 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cell division control protein 2 homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">cdc2-related kinase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_014526</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">May form a complex composed of at least the catalytic subunit CRK2 and a cyclin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6H2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010556">
        <property type="term" value="P:regulation of macromolecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007346">
        <property type="term" value="P:regulation of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080090">
        <property type="term" value="P:regulation of primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000172">
        <property type="entry name" value="cyclin-dependent kinase G-2 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF107">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 11A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="21"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00042858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1734653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="305" mass="34424" checksum="93052822DFA12453" modified="2024-05-29" version="1">MPKADRWSSDEEEIVLLSLLPKPISHLDEGTYGVVWKARDNATQEIVAIKQIKFDSDMTKEGFPISALREIGVLLSLSHESIVSVREMVVGSTPDKVFMVMDCFEMDLQAAMKKGPGASTPFAQSEVKYMMRQILSAMAHVTSIARKYEHPARNMTQMVVTLWYRAPELLFSESCYGPEIDTWSIGCIFGELLIKEAILKGTGELDQIQKIFKLLGTPTDDEYWEQLWSKQGSTFKWKNNDSDLARTFAVNSFSATGQSYLSPDGFDLLSRLLSLNPKKRITAEDALRHSYFSCGVTEQVPMFYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6M3</accession>
    <name>A0AAD9D6M3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FAD-dependent dehydrogenase</fullName>
            <ecNumber evidence="4">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_013242</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6M3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028348">
        <property type="entry name" value="FAD-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049516">
        <property type="entry name" value="FAD-depend_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42842">
        <property type="entry name" value="FAD/NAD(P)-BINDING OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42842:SF3">
        <property type="entry name" value="FAD_NAD(P)-BINDING OXIDOREDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21688">
        <property type="entry name" value="FAD-depend_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042248059" evidence="2">
        <location>
            <begin position="17"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-dependent protein C-terminal" evidence="3">
        <location>
            <begin position="440"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1736106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="746" mass="81942" checksum="7900D5EFD71A8BF8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6S5</accession>
    <name>A0AAD9D6S5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_014338</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6S5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="3"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="68"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1734878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="287" mass="32239" checksum="CF7DF58127F5E1A4" modified="2024-05-29" version="1">MCCASCGIAEVDDVKLQKCDACDLVRYCSDKCHEDNRPTHERACKERATELRDEILFKQPESSYLGDCPICFLPISVEFFVQSCCSKMICDGCSYANARRETKQRQTCPFCRHPVPRSKEEIDKNNNKRVAANDPIALMQMGMDYHKKGENEAAVDHLTKAAELGFVEANFKLAFFYEKGLGVEEDEKKALYHYEEAAIGGHCDARYAVVFHEMQNNRSERAIKHLIIAANLGHDHSIKVLKMFYSGGRISKDQFASTLRAYQAAVDATKSPQREAAAIIMAAEGNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D790</accession>
    <name>A0AAD9D790_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_012788</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D790"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044669">
        <property type="entry name" value="YneE/VCCN1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281">
        <property type="entry name" value="UPF0187 PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281:SF19">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION CHANNEL-FORMING PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25539">
        <property type="entry name" value="Bestrophin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="163"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="166"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1736766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="427" mass="47475" checksum="9E2A0CFADC91928D" modified="2024-05-29" version="1">MIATQSGWQPYYCIDAMRAAISEGLTAEGKNDEWKKNAAQAAMEETICTLANSIGGCIRVRSTGLPVAYDDILNTTGAIFFTAACLAWAPGAGLYNPFVVLIVYTIVKMIIGVGSDMEDPFGHDESDLPLEKFCEEVDKQITAVDERAKLITFDLAYGPASHIPSERSSSYSTFPNRRGSPLANGDNDVESGQMSSETDRLVPAQRVFLSSVNGFAAPRILHAAAAVRPPSLLHAEKSKDGEDNFISDFCIGTNTFWKGLVMKPVRDLVEIRPATITPDSPIIDKLTSPPELPGIPRPVWLTILGVFQRVWFGMVTTSSVWKKSSINMSCSRRGKLVDVEAMERCSLVGGAAAASGCCRWFETSHFLSEYWRVKRGDTKQDDVIAETLFPFISLPEKFTLKQFFARPKHWFWFTKEWKDFEFEFLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D881</accession>
    <name>A0AAD9D881_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012948</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D881"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="369" mass="40584" checksum="4EA286CE64650773" modified="2024-05-29" version="1">MDIFDAADLLAIEQDALSFSSSSCSDSAADGSFKASDNPVHEDKDDSLSHPNESQLDDGHPLNSKQSSTQNLLGGNVEASGDDDDSSDDGFLESMLTLKNESTPNNIQHTSDEKKLLQEEPESDTKVCCHETLNDRVEARNSLDENEKLDVAILFGDSIGRWMTSHQASKEKPKTKQTRVKERPMCKHYDGVTSIQNIQDRLNDDKQSFPLRLSIGKKRKRQSVVGGEVAEATLEQFHVSSDDTQNNGNRQQICGIVAIAPDAERASIGTMVDCLARYDHEKGAYILEIVDLDVSGLGLTATTTPEHGKDAENGEIAALTEKYKSAIADPRSRAKQAEKQVRKLKQGKRTRSERKHPDANTKITNSVMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D972</accession>
    <name>A0AAD9D972_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D972"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="277"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="855" mass="96878" checksum="00B7E3ABEE263340" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAV4</accession>
    <name>A0AAD9DAV4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA pseudouridine synthase, RluA family</fullName>
            <ecNumber evidence="4">5.4.99.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_008672</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAV4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluA-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050188">
        <property type="entry name" value="RluA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600">
        <property type="entry name" value="MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600:SF87">
        <property type="entry name" value="RNA PSEUDOURIDYLATE SYNTHASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="3">
        <location>
            <begin position="201"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="116"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1740577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="393" mass="44592" checksum="AFDDC841CFF66625" modified="2024-05-29" version="1">MSSNNIPQHLRIRIIHADDDIIVIDKPANLRSVPGHADSPTDTTIKLKRPSDRLTAVEAWIQAIKSIPLDDSDSYKNEYVKELLQNICTTNNLSSIPRKLEPFARYVFRNRKRLLPSHIDDEPDGGKNEPPQKKQRNDDNLAQKTKQPSMLPSMRGAADEAFSIIQRLHIPLMNLPTPTEDWESAQGQLRLLGYGDFANENNHSLSTSEKRKLHVVHRLDCQTSGVLLFARNPESASKLCKAWRERDVVQKVYLAHVMRWPPYDDQKLEEGTIELPLAASRTERIKWEVRELDDGGKSSITKWKIYKDADSGEDNTTKEGAILELHPITGRTHQLRIHCAEIGSGIVGDSLYGDSPVPWDAGKPTILRLHAQMLSLRHPRSGEELTFKAPRLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBG5</accession>
    <name>A0AAD9DBG5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DnaJ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_009422</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBG5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026894">
        <property type="entry name" value="DnaJ_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052423">
        <property type="entry name" value="EMIR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44094">
        <property type="entry name" value="DNAJ HEAT SHOCK N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44094:SF8">
        <property type="entry name" value="DNAJ HEAT SHOCK N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14308">
        <property type="entry name" value="DnaJ-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="186"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1739663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="544" mass="58455" checksum="935859A2CD0C66A4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBN0</accession>
    <name>A0AAD9DBN0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Exosome complex component RRP41</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009004</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBN0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050080">
        <property type="entry name" value="RNase_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953:SF0">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="2">
        <location>
            <begin position="24"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="297" mass="31130" checksum="A68CFE0445D7497E" modified="2024-05-29" version="1">MTSLQRTDILSLIHLRSDGRRPNEIRHMTCHLGALPPTTDCGSALPSSACSGSAMVTMGLTQVLCIVRGPCDVGRRTEELPDRATLEVTMRTAPFAPPGDRRSTNPTSDRRLIEQSHLLQKALSASILLHLYPKSKISVTVMVLADDGGRLEAAINACTLALIDAGIPLKDMVCACSAGRWNAGGSDEIVVDLNRREIQAATGGASGGGGGNNSGGGGGTSDTIYLPVATMPQRGTVVLSQCESRLSGGAEAFGEVLECARAGCEMVMEVMAAAVRERGAGLWKAREGKATVVLDDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DC24</accession>
    <name>A0AAD9DC24_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_007440</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 5"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DC24"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050689">
        <property type="entry name" value="FKBP-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516:SF443">
        <property type="entry name" value="FK506-BINDING PROTEIN 59-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041976645" description="peptidylprolyl isomerase" evidence="6">
        <location>
            <begin position="17"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="7">
        <location>
            <begin position="154"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1741867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="236" mass="25789" checksum="4FFB51A6BA213D47" modified="2024-05-29" version="1">MHFISTILLLATSCDAFAPSTRLTSKSSTVLFASEEWIPLVTDDSSEASPVKKLVLEEGNGELPTDGSSVEIEYTGTLVGEKDWSAQDVADCWLSQLQGLDHLKAEFIQNNIDFALLSDTNVFTEEFCTTTLGISNKIQAKKLLMARNRLTKSQDEHPAGTVFDSSAERGKNFTFNLGKGAIKAIDLAVRSMRVGERASVVCRSDYGYGSEGLRSSKGDVMVPPFSTLNFELKRVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DC85</accession>
    <name>A0AAD9DC85_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">CLC voltage-gated chloride channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_008510</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DC85"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015108">
        <property type="term" value="F:chloride transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00400">
        <property type="entry name" value="Voltage_gated_ClC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3080.10">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="ClC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050368">
        <property type="entry name" value="ClC-type_chloride_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43427">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN CLC-E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43427:SF12">
        <property type="entry name" value="CHLORIDE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042195794" evidence="6">
        <location>
            <begin position="24"/>
            <end position="552"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="227"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="264"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="457"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="489"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="524"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1740415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="552" mass="57878" checksum="A1D141CCECEDB64A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DD61</accession>
    <name>A0AAD9DD61_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007883</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DD61"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="230"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="326" mass="35556" checksum="D85BCD9D7518881B" modified="2024-05-29" version="1">MVAKRLGVGAASSSSSTAGGASENVSEDWTKSIKKQILNVGKKRRHDNIYGEDDDDDNAAADGNSSSDEEEGRTTAVKERKKKKTTVPVVSTDASSSLDVQGDVTTNDDTKSKKKEKKKGKKERIQEQQDAAAAAESTKEGEVAAPSSDKEQTTEVTNTTESKKPNQKRKRPKVRSRQKNIAKDSRAANDKPSHLVPGRDDYAGRAMTQTTREKLGLGKSKSSRKSKKSVKLDDAFEKGEWVDEDGLKEEGKSTSKVDVAPDPDGNDDAKSSADVGESVEKQKESSKEENKLQMIGDCIVDYEPSSSTPAKQKKKKDKKKKKYKNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDB4</accession>
    <name>A0AAD9DDB4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008063</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDB4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042284046" evidence="2">
        <location>
            <begin position="20"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="562"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="988"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1037"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="562"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="991"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1006"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1037"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1061"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1085"/>
            <end position="1111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1157" mass="122173" checksum="DDD83F317B3B9088" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDC9</accession>
    <name>A0AAD9DDC9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">U3 small nucleolar RNA-associated protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_006122</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UTP6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDC9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013949">
        <property type="entry name" value="Utp6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055347">
        <property type="entry name" value="UTP6_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23271">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN 66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23271:SF1">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 6 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08640">
        <property type="entry name" value="U3_assoc_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 6 N-terminal" evidence="7">
        <location>
            <begin position="8"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="83"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1743501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="718" mass="82467" checksum="319BC6BA09D486F1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDG2</accession>
    <name>A0AAD9DDG2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007186</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDG2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="807" mass="90067" checksum="922EC4D85B95FD39" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDV9</accession>
    <name>A0AAD9DDV9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007666</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDV9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="61" mass="6741" checksum="1F72CE05360A2C64" modified="2024-05-29" version="1">MVASEDPLTPVQMAINGVKLLVAMSPLIALFYVIYTGFEDEEKEQAKRKQKGDFALDGHGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DE00</accession>
    <name>A0AAD9DE00_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005429</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DE00"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1743832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="380" mass="43512" checksum="AD1212E8FFDA44B1" modified="2024-05-29" version="1">MKNAGVTVPFEALVHNDIILSLQDSTYKTIMYQYYRKLEEKTKDGIRNEEEEMKTKEEVYKLLKNAGGRLLNYVDYRTPNSGFFQVDEETARAKIANDISRRNESKGIWGMIAISSPNKSVVSHNKMIVPQNIYLSLKNDFYRENLFAYFHKLGTKTESQRDSDEEKRVKEEAYNFFKTSGGKLVKHNDWKKPELGYYEVDDEYARRKISDDIRRRLETRNRWDVVDNGAATSAARNNGSGVMDLHKLAEIASVEDEEELPDASLRLYSHSQGTVIHVPPVAAPREQIEKESPRKEPHGNAGATYSYLDIYTLEYLKMWLTMPSHIEDPYPTEADKNQIIRDTGIAKTLCIIGLLVIARGSGSLPSKTYEPSTASKRLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DE16</accession>
    <name>A0AAD9DE16_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004709</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DE16"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39444">
        <property type="entry name" value="SITE-SPECIFIC DNA-METHYLTRANSFERASE (ADENINE-SPECIFIC)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39444:SF3">
        <property type="entry name" value="SITE-SPECIFIC DNA-METHYLTRANSFERASE (ADENINE-SPECIFIC)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="339" mass="38829" checksum="6CE256911E1B5B4C" modified="2024-05-29" version="1">MSSKQPKQNKKRKRSATKTAGDDHDTKSNNRTDWSSGSYPYPTDYNDHFETPQRAYADIYPLLQYCLQKDKKSNNEEAIIYDPYFCTGTAATLMDQTFKSNKDKSPLPSPVRIHHKKADFYVDVKQNKFPQYDILVTNPPYSSNHKERCLDFAVNQLKRNGRPFFLLMPNYVSTKEYWRKITQNVQVVFIAPSTSHPYEYNHPEGTGHEKSPFESVWFCGVSGNEDMKALKDAFIKFHSKHTSTPIPRWAESLQGLIQVGGVSGEKRKNPRQRKKMRLLAMQKSSAAGPPPSSAQVTNTTLPSSVQKKDGRPNKKFDRRKQNSAKKTKKKRLNSGNDVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFJ6</accession>
    <name>A0AAD9DFJ6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004862</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFJ6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006461">
        <property type="entry name" value="PLAC_motif_containing"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01571">
        <property type="entry name" value="A_thal_Cys_rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15907">
        <property type="entry name" value="DUF614 FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04749">
        <property type="entry name" value="PLAC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="431"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="473"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="503"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="600" mass="65749" checksum="8F538152E2F1B4CE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG48</accession>
    <name>A0AAD9DG48_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_004876</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DG48"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="190"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1744343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="249" mass="28581" checksum="ADDD15BB06586B64" modified="2024-05-29" version="1">MASRKKTKRRKKAKGKAAKAAAFKPFSLTQFKKSTCTHGWDHTEYSDNHDCHKFIEATIEAFERTKSISDIFDAAEKAALEHKYPEIWKDPSKLEWIASALVSIGVEAYCCEDEDFLCVSSAAFSEWIHQYIAHDHHKSMPSVYSARLHELLYADERRIIGYLKKRIPCSCLNSSYNMVKHLPKKGICGSLGCSRPERKVELSEMWSCEACRREHYCSEECQAADWSRHRGECKVWSEWKANCGSSQPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGT2</accession>
    <name>A0AAD9DGT2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGT2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1745290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="93" mass="10479" checksum="F9C1DD46F111415B" modified="2024-05-29" version="1">MNCALLKEVVMDFMVEKRSEVLDKVSHDAPGGLLADILAATSRKFNQDGARDDDFNVMRISDLRKEVHGKGLDIDGSRETLMLLSKRRLDFNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DH41</accession>
    <name>A0AAD9DH41_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TLC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_001544</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DH41"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050846">
        <property type="entry name" value="TLCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439">
        <property type="entry name" value="CT120 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439:SF0">
        <property type="entry name" value="TOPOISOMERASE I DAMAGE AFFECTED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="7">
        <location>
            <begin position="67"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1747581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="308" mass="34577" checksum="CB7129C08C6E31F3" modified="2024-05-29" version="1">MTKPPPLIFENSHDGGSLPALQMLVTDIFTWEILYQISQFAIKVAFMKYSKIIVNPKKANSDAAKATLMELGPSYVVSFVHSLYVTARGVMHLYSLWAASNMDKIYIGPEGDYREAHLEVARTNILFVAYLFYDMIHILHQYPKLGGGDTMAHHMLFAFCSVINGTFGIMPFQFGWLIVGEMSTIFLNWRWFLLKSGRDSGVLLENVNTMFAASFFLTRIVMYTAGIVHLYIFSMSELKSLSSPEVSGVPLSALGITCGCMLLGWLLNLYWGSKILRKVARGRTNVTVKSTEPVAAKAGKKNRRSKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DH94</accession>
    <name>A0AAD9DH94_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003437</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DH94"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050817">
        <property type="entry name" value="DjlA_DnaK_co-chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24074">
        <property type="entry name" value="CO-CHAPERONE PROTEIN DJLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="13"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="180" mass="19818" checksum="7C22330C7ACEA92D" modified="2024-05-29" version="1">MVFFSPHGEPLCNPYLILETEFGASDDDIAKAYKKLMLQLHPDKQPVDQSEEEAEEVSRRFHAVMGAKSFLLDGEHLASRREYDARLAAKEKANTAAAAREATRVKTQARQAAQAKAQQQKQQQSAPSSPQSTSVKVHSASKTKATTKSTSKKVEPSKGGINKTEDTCHSYDTPVLVEFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHD5</accession>
    <name>A0AAD9DHD5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003557</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHD5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="170" mass="19011" checksum="0F0D6ADE3213D9C9" modified="2024-05-29" version="1">MEEEEEDEDEEESEGGSEDDYSDDEEEETHYFIDTLRTIVDATPLSQLLLSPRGEEHETVSSLQVQSLVSVINADLSGRALKNEPKHVVVETCSHIIIAMQGINQQIMQDKALYADPMGMDAVNRALSTRIKRLPADRMHNIDGCVTILDPPDTSDQVQPSTIVRRSRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHI4</accession>
    <name>A0AAD9DHI4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Vacuolar protein sorting-associated protein 52</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_001979</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS52 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1748016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHI4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000938">
        <property type="term" value="C:GARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007258">
        <property type="entry name" value="Vps52"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048361">
        <property type="entry name" value="Vps52_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048319">
        <property type="entry name" value="Vps52_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14190">
        <property type="entry name" value="SUPPRESSOR OF ACTIN MUTATIONS 2/VACUOLAR PROTEIN SORTING 52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14190:SF7">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 52 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20655">
        <property type="entry name" value="Vps52_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04129">
        <property type="entry name" value="Vps52_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vps52 coiled-coil" evidence="6">
        <location>
            <begin position="92"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Vps52 C-terminal" evidence="7">
        <location>
            <begin position="291"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1748016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="745" mass="84050" checksum="EDEF0CCA18C9A97D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHR3</accession>
    <name>A0AAD9DHR3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHR3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="entry name" value="Intergrase catalytic core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="562"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="715"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="579"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="733"/>
            <end position="742"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="761" mass="86502" checksum="D8DBEA857552CC26" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIU4</accession>
    <name>A0AAD9DIU4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_002599</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIU4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:001091">
        <property type="entry name" value="STE family protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050629">
        <property type="entry name" value="STE20/SPS1-PAK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012:SF2">
        <property type="entry name" value="STERILE20-LIKE KINASE, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012">
        <property type="entry name" value="STERILE20-LIKE KINASE, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="47"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="375"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1747255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="644" mass="70235" checksum="D1D57E81B7E723EA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJ51</accession>
    <name>A0AAD9DJ51_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000003</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJ51"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042248991" evidence="1">
        <location>
            <begin position="17"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="191" mass="19848" checksum="8A352ACF8DD44304" modified="2024-05-29" version="1">MKLQIVFLSLLVTAHARYEPKGLRGGDDRDLELDTVQIDHIIPEGGSATIHCGSGSQCCVASSFKVVDDTGPSEWGSGCNDGFSSITDGTAGVCQMEVCTISCDSPSCKVDFEAGSAGRGGFVAAALTTYSLSNTNVPTHFTGGSGGGHGGMGGWWWSSRTLMLCYFTTFGRNPGGGGGGDDDNGFYMEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DKQ0</accession>
    <name>A0AAD9DKQ0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Serine/threonine-protein kinase PLK</fullName>
            <ecNumber evidence="8">2.7.11.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Polo-like kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_000887</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.21" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DKQ0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13118">
        <property type="entry name" value="POLO_box_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13117">
        <property type="entry name" value="POLO_box_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14099">
        <property type="entry name" value="STKc_PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1120.30:FF:000013">
        <property type="entry name" value="Serine/threonine-protein kinase PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000091">
        <property type="entry name" value="Serine/threonine-protein kinase PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.30">
        <property type="entry name" value="POLO box domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033701">
        <property type="entry name" value="POLO_box_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033695">
        <property type="entry name" value="POLO_box_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000959">
        <property type="entry name" value="POLO_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036947">
        <property type="entry name" value="POLO_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345:SF0">
        <property type="entry name" value="CELL CYCLE SERINE_THREONINE-PROTEIN KINASE CDC5_MSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00659">
        <property type="entry name" value="POLO_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82615">
        <property type="entry name" value="Polo-box domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50078">
        <property type="entry name" value="POLO_BOX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 8 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="128"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="POLO box" evidence="11">
        <location>
            <begin position="548"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="domain" description="POLO box" evidence="11">
        <location>
            <begin position="664"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="95"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="477"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="636"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="95"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1748948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="748" mass="83108" checksum="96FA57AE734718BE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2020-12-02" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6U3TS88</accession>
    <name>A0A6U3TS88_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_012314</name>
        <name evidence="5" type="ORF">SMAR0320_LOCUS4580</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the proteasome complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase T1B family.</text>
    </comment>
    <dbReference type="EMBL" id="HBGZ01006504">
        <property type="protein sequence ID" value="CAD9584368.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6U3TS88"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005839">
        <property type="term" value="C:proteasome core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03757">
        <property type="entry name" value="proteasome_beta_type_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000027">
        <property type="entry name" value="Proteasome subunit beta type-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF2">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CAD9584368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1736869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="280" mass="30519" checksum="325E8B2547C98A02" modified="2020-12-02" version="1">MASLLSATNAVQSRNGQSCLPVHSSEGQATIPVRFDGTNLSISSNNPTANIIDGSSIDHGITKAPYERSFSPYEFNGGTTLAISGPDYAVVAADTRLSSGYEILSRNVSKLHPLTERCVLGSAGCKTDVDQLRSVLDIKMKVYQHNHRKPMATPSVAQMLGNTLYMKRFFPYYSFNVLAGIDSEGKGAVYSYDAIGSFERTPFSASGSGQAFLIPLMDNVISHKNRCDEQRDLPVEEVVEIVKDAFLTAGERDIYTGDAVEIKIITKEGIRTEMFNLKAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSC0</accession>
    <name>A0AAD8XSC0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">AP-4 complex accessory subunit Tepsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_016716</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000063">
        <property type="protein sequence ID" value="KAK1732575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSC0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032588">
        <property type="term" value="C:trans-Golgi network membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03572">
        <property type="entry name" value="ENTH_like_Tepsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035802">
        <property type="entry name" value="ENTH/VHS_tepsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039273">
        <property type="entry name" value="TEPSIN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21514">
        <property type="entry name" value="AP-4 COMPLEX ACCESSORY SUBUNIT TEPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21514:SF0">
        <property type="entry name" value="AP-4 COMPLEX ACCESSORY SUBUNIT TEPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="213"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="280"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="409"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="660"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="726"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="216"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="242"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="312"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="330"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="415"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="426"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="660"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="726"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="743"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="755"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="766"/>
            <end position="798"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1732575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="901" mass="90608" checksum="6A84A66559B70F1B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XT40</accession>
    <name>A0AAD8XT40_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Leucine-rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015918</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000050">
        <property type="protein sequence ID" value="KAK1733359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XT40"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="317" mass="35863" checksum="9DFDEDF2A9F61B9D" modified="2024-05-29" version="1">MMAADEWYIYYGRDGEVIPPGVTRVRIHESLTVIRAEAFYGNRNIEEVACHDRVKTVEEYSFAGCPSLRKVIMPGVEVIEQCAFNSCEALAHIECGKLEIIGVGAFETCQSLKSINLPSVKIVERSAFTVCKALTNIKFGKELEIIRYRAFWLCTSLERIAIPLKDGIIADDGIFMGCRKLKHVELVEKAVLRDTIAALLLEEWRNDMNEEINAINQSLPTTPAGSDDFYDVGEKTEAVQLWIKSVLHKIVRYKAQHHSLLNEAATTLQRALPNDIVNKNVLPFLELPSYTFEERIRRGRRRGIGRRGGGNERLRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTP9</accession>
    <name>A0AAD8XTP9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015943</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000050">
        <property type="protein sequence ID" value="KAK1733384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTP9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="321" mass="35796" checksum="792DD47D3EE775E5" modified="2024-05-29" version="1">MADVRRMTNGHHQPTHPTDADASKRIAALEATNTALREALSSKNSHIAMLEERLLTMSVELASSRAREDEQNLMLRQSTGQVVSQEVIMMSEEDDDHDDNMNIPDSLVPNPVRNGRRRRGSRGSSAVSPCPDNSAAIDDSIKSAPPAAAQQTSSMRRFSFMSNHHDFDDSARSLGSTGVGGIIGNIFNNLDRSDKSDDLSVNFPTGRRRSSMMTSDTTNDYYSATSSSVGNSQEPRRVSMVGQLFRLRKSELTPDDAVEEESCEQEEEEEEQQPAEEEEQPMQRRRPNRSKLANRYMMSTRLISSTVAFPREDDDDCLGFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTQ4</accession>
    <name>A0AAD8XTQ4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_016010</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000051">
        <property type="protein sequence ID" value="KAK1733293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTQ4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006418">
        <property type="term" value="P:tRNA aminoacylation for protein translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1910">
        <property type="entry name" value="Cysteine-tRNA ligase, C-terminal anti-codon recognition domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042041270" description="SAP domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="SAP" evidence="3">
        <location>
            <begin position="522"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="470"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1733293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="556" mass="61085" checksum="21E3C6E541FB9E97" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUF7</accession>
    <name>A0AAD8XUF7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUF7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000093">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="1">
        <location>
            <begin position="43"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="306" mass="34788" checksum="178CD1C52C63AFFA" modified="2024-05-29" version="1">MQSSTRAAMEELDCLLVKEQSAQYQISPTLLWNLNGKDNKFSSPLRWRHAICDWYYDFVDHFHFDREVVGVAANYFDRYTSINAVSLDDNENALSTYHTVAVTALFLAIKLHATSCEVDDLQELRNRALSKILHGTPQPKNILDMEMNMLKALEWSVNPPTLHQFTFMFHKFPPSREICAAYEFYIYEATRYQVELAIYVPQLLAEFKPSIIAFAAMKNAEEKIAAGNPVPTTNMKLSCKALTSHSGVVVDSTVVTRCQILLKIVCPELPDLERFHEAATHGTSFDMQVDRHLMNSPTIVVTFDGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUR7</accession>
    <name>A0AAD8XUR7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015227</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1733969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUR7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="157" mass="17433" checksum="D68C7B5D6BDDD93C" modified="2024-05-29" version="1">MKMSSTTKTRSVRFADTAQLYIVGRHEDYKNKINSVARHDLWYTKSDYYSMRRAIEQDVLQVRAQALVGAPFNYAGDDEASAFESSVCCVGIEHLLTPAFILETAACRARCILAVLIAQAQAGLDVSELDIALASLTQTRSAQLRARKRGMLLQDSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUZ7</accession>
    <name>A0AAD8XUZ7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_015171</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUZ7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24186:SF46">
        <property type="entry name" value="PROTEIN ACCELERATED CELL DEATH 6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24186">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="77"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1734168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="151" mass="17153" checksum="F2F9578971FD0E76" modified="2024-05-29" version="1">MMTPDSNGQLPLHTALQNNVRLGSIKLLVKGNPSAIRTVDTNFALPLHVACQHHDSITIIQYLLGLDMRTLRAVDYDDNTALHYACRGARHEIIALLLEKYEAVSVSKRNAQKKVPIDLLWESNEEDRESVEYTESVFRLLKAYPETLMCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVF6</accession>
    <name>A0AAD8XVF6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heat shock factor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_015166</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVF6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF206">
        <property type="entry name" value="HSF-TYPE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="6">
        <location>
            <begin position="51"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="180"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="283"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="10"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="291"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="310"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1734163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="400" mass="43188" checksum="E3EAE89A589B344E" modified="2024-05-29" version="1">MPPSPPHPPVVHVGKKSPTAGAASSASVDSTSTAQFDDNQAATNSVSSFLQGKTFVQKIHVLLEVPKYSSIISWNDAGTAVLIHDVDAFISTIVPAHFKQSKFGSFIRKMRRWGFSVITKKHSTSRTSTSSERGQSAVMEFSSEHFLRDQPELCLLMKDERHVKTQFSFLDRTVRKANGRGQDVKQGSSVGVCVHSPRTSNANSVENKSESQQLSAGVGGLNTTMNSCYPRNHAHANSVPPMITPHQQQESVHNAVPMMNMMMPPLPQYPPYGYGAPPLPPQAPGLGFGPSSPPFQPPSAPNVYSPYPYQQQQSLEQQNQQQRTPPQADCENLSAKSSKRVLATDFAASATPNGCSDPAASTASGSAAVLLTSSEESTELLPSQGHEPSDQTVFWDQAIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW28</accession>
    <name>A0AAD8XW28_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DUF423 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_014611</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XW28"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006696">
        <property type="entry name" value="DUF423"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43461">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43461:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04241">
        <property type="entry name" value="DUF423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1734738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="132" mass="13588" checksum="355CF48350440995" modified="2024-05-29" version="1">MGNETSETLRKLAAALGASGVGLGAFGAHALKGYLNKKPEGSNNWKTAVSYQLLHAVALLSLSCLEEGKPRKYQGGGGWSGGKIMALGTVLFSGSIYLLTLDIGPKRILGPMTPVGGLLLMSGWAMIGAGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW31</accession>
    <name>A0AAD8XW31_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">magnesium chelatase</fullName>
            <ecNumber evidence="2">6.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_014818</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Porphyrin-containing compound metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mg-chelatase subunits D/I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.6.1.1" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000038">
        <property type="protein sequence ID" value="KAK1734570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XW31"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016851">
        <property type="term" value="F:magnesium chelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01451">
        <property type="entry name" value="vWA_Magnesium_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.80">
        <property type="entry name" value="Magnesium chelatase subunit I, C-Terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041702">
        <property type="entry name" value="BchD/ChlD_VWA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052989">
        <property type="entry name" value="Mg-chelatase_DI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35023">
        <property type="entry name" value="CHELATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35023:SF1">
        <property type="entry name" value="MG-PROTOPORPHYRIN IX CHELATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="5">
        <location>
            <begin position="308"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="120"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="150"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="189"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="201"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="231"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1734570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="500" mass="54985" checksum="8A4AB562C54D5C5A" modified="2024-05-29" version="1">MVDVAAPTDVEERCEVVRQRMQYERYPVEFGAAWADAEKDLTEQIKAAQERLPNVILNDELLLLISKICTEFKVGSLRADLTMYKAACALAAYRGRLEVVPEDVKDVTEWVLAHRRRRQPFESPMDGPSMDDLLDELMNSLPENSNNQSEGDHDEPNQQNGEDNKSTTEGSSNNNGKDDATTEDETSPDDNGQSSKQNEQNTNNDDGNGSNNDDQMQTFTASKPGQIKQLRLNQKQSGQTGSGRRNSSTNSQQKTRYIRSAPTDKAVDLALDATLRAAASNGLSDDGQPIIHPENYRKKVYNSTTDTLILFVVDASGSMSARKRMETVKGAVISLLMDAYQQRDKVGVIAFRGTKAEVLLEPTRSVELAEKQLQRLPTGGRTPLAHALSLTSDMIHRLQRHEPDQALLLIVLSDGKANVALPTTDSNSTDVDVGDAWKQTEQMAAQLGQLDVPTLLLDTDSGHVRVGRGKELSHLLGADYLLLEDMTADGLVHTIRQAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWV7</accession>
    <name>A0AAD8XWV7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_014407</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWV7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="7">
        <location>
            <begin position="15"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="81"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1734947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="307" mass="34874" checksum="E1995BCC5A8EC41B" modified="2024-05-29" version="1">MMSNDLQAEADCMCCASCGITKAEFEYELVPCWVCNFYLVRYCSEKCHEDHWPQHEALCKERVLRNEILFRQPENTHLGDCPICLLPMSTGLGKSMIQSCCSKTICKGCSHAHCLHQLQQRQARVCPFCRHTIPKSKEEVDKNNLKRIEANDPVALREIGTERYHEGNYEESFEYLAKAVELGDIAAQYYLGHMYQKGEGVEKDEKKGLYHLEEAAIGGHPEARYSLGSREWKNDLIERSMKHYIIGANLGHVMALKVLKESYKWRDVTKADFAGALRGHQAAVDARKSPQREAAAIFQATQAGNAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XX57</accession>
    <name>A0AAD8XX57_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">methylated diphthine methylhydrolase</fullName>
            <ecNumber evidence="6">3.1.1.97</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_013901</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>diphthine methyl ester-[translation elongation factor 2] + H2O = diphthine-[translation elongation factor 2] + methanol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:42656"/>
            <dbReference type="Rhea" id="RHEA-COMP:10172"/>
            <dbReference type="Rhea" id="RHEA-COMP:10173"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:79005"/>
            <dbReference type="ChEBI" id="CHEBI:82696"/>
            <dbReference type="EC" id="3.1.1.97"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DPH7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.97" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XX57"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061685">
        <property type="term" value="F:diphthine methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052415">
        <property type="entry name" value="Diphthine_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46042">
        <property type="entry name" value="DIPHTHINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46042:SF1">
        <property type="entry name" value="DIPHTHINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042184302" description="methylated diphthine methylhydrolase" evidence="9">
        <location>
            <begin position="17"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1735287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="447" mass="49019" checksum="ABEC00B29380F35C" modified="2024-05-29" version="1">MLVAWLLGLLFSESDPGETTLRRHHTAGKMSTQEEKDGWFDALTTPLNACSLETYFPITRDDGINSSSDKPSDVPLVVGCYQLNESSQSDPEDPDTASSSAGSSRCGELRLHMIPTPSTSKTAMQFGDAACVLQMESGVLDGKWKRRRKNNQTAVEIPLFASACASGSIHIHGLEKNMSTDSTTDTTSWSLNHLASTDGQIDTGLCLALAWNDYLNESEDQIVSSYSNGEVAIHQVSYHGDTNKAPKLEETHRWNAHTLFGCPSEVWTCSFLRGAENVVLSGADDCSMKIWDIRQTQRPVHKVGDTEFEAGVTAISSHPSLDNIFAVGSYDEHVRLYDYRKMAEPLSRVSVGGGVWRIKWHPSTWSGESSCRGKLLVAAMHGGCRIVNFPSLDGGVEEYTAEEADVLSEFTAHESMAYGADWISFGSPELEAAASCSFYDRKAFIWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XY61</accession>
    <name>A0AAD8XY61_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HTH psq-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XY61"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:DNA transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002514">
        <property type="entry name" value="Transposase_8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01527">
        <property type="entry name" value="HTH_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="453"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="481" mass="52006" checksum="275BEBD532660A00" modified="2024-05-29" version="1">MSSNEPLPSSAPAQVLGGVELVPALPPVPAVGDVSAVAAAAPPPAVQEIQGISTSKLLEPIQREAPKLGRKNGVSNLTASQKLDILHELDSASAAAAANGGGDVAAATTDDAAAGEKSTVTKLAAQYNISRQSIYRWKKEMPRLMEQAKEQQLQQQDGSDGMTAALASATRKRGHGETMTLLAESDAMGGAGGGAVDPNVAILVKKPTGEEYTAQQKLAMVRQLKSNSKDGNKLRVREFASKHGVNYRTLYRWIKSEERLVELVEGEGMGSFKRTKFDGHLDRIKEALKVFVAHYTKDDDAADGEEGKAKKITGRIIAEKAKHIKEEMLAQHEVEPFLSGEEVKAMREFTGSQSWGRKMCRRYGWGNSSETGNKKKGDDDDVSDDDDDVELNDGGEPVDMTETDDPAKMKLQIKKLKSEVHFLKIKSGKFEKKAAKSETENKSLRKQIEVLKSKDATPSLPLPSVPDAAAYETEPTVEVNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZ30</accession>
    <name>A0AAD8XZ30_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ER membrane protein complex subunit 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012573</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZ30"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22209">
        <property type="entry name" value="EMC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39219">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39219:SF1">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042230342" evidence="2">
        <location>
            <begin position="24"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="292"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="310" mass="33224" checksum="FA369E6B6E5F66AD" modified="2024-05-29" version="1">MKSIRNLLFSGVTLHCVAGIAIASDIGKSYQLYHKLGSQSELTPRGKILISPSDNDGIGLSATFIKDNSAKLDTNAFDSMVDSSALYTVVVIEDGDDKSSLSLSSLNGAPHVSASVPGCSLRRSNLREEISLSISPTGKLQSVSYRPLISPLTSKSCDNLKALSEKPEAIYGREGGNDEPFPFKTTVEFESHKPMPTIPIVLPQTRPPAGLKWYRRNAKNSPNPFLGGSNVENKGGIPFVDEEAPSGFKSSFLYKYWYIILPLALMGLFGGVEEEPVQDTSRGAPVVATTMAGAAAASGGQARQRRGKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZD8</accession>
    <name>A0AAD8XZD8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_013217</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZD8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051419">
        <property type="entry name" value="Lys/N-term_MeTrsfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12176:SF80">
        <property type="entry name" value="EEF1A LYSINE METHYLTRANSFERASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12176">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042291395" description="Methyltransferase domain-containing protein" evidence="4">
        <location>
            <begin position="16"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase" evidence="5">
        <location>
            <begin position="115"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1736081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="295" mass="33464" checksum="CB43B62AD032295E" modified="2024-05-29" version="1">MSWIFAVILITPAFGFTSCDSFLMNNRRLRHLQAKQEGSTHNWNHEPFDFSSRIGWDNFYKEGNPSDDEQSLENLEYEWHSHMPHSVIVDAIAPTIDAASKYYNTAAVDNEIPSILLVGTGNSALPRILHDAFDTPVRVTCLDYSPVCVEMIRSMYADLCPNMDFVLGDATCLKETLNSDKYDVIVDKGLLDALMCGEGFDSDLEKLMAGIDEVLTRREWGMSILVCFQLSKSNREFLIELADCGTSHNPNLFWDFDIPVEGSENGRATFNLARRCALDEKNRIVNIDHMITDWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0E8</accession>
    <name>A0AAD8Y0E8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012138</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0E8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="116" mass="13334" checksum="DDE32EEFFE8EB5F0" modified="2024-05-29" version="1">MGTRVDTLHKTFGPKGFMAGVKKFRWGQWTAMAAHGYMDESSASQIKSFSDKFQQRYSGDIKKYILDIERYQLLTDGQRCHQTVEDDPLANNEIHPVGQEHSDLYTYFSDGEDYGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0R3</accession>
    <name>A0AAD8Y0R3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011767</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0R3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43036:SF2">
        <property type="entry name" value="OS04G0481300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43036">
        <property type="entry name" value="OSJNBB0011N17.9 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042214442" evidence="1">
        <location>
            <begin position="18"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="237" mass="26171" checksum="BBF2BFD340A668C5" modified="2024-05-29" version="1">MMLYVVLVASSLQYASAFSSTTTNRITTPTTNNLQQRRQFLSSISTSIIVQSLATQPANAAIRDPKQTWDEDDNPFASLSESVSFSRLDASDDKIFYAEPRFVEHVDQQAVDSITSYVSDSLLQNGDSVLDLCSSWTSHITPGKLDLKRVAGLGMNAKELEANKALTEWAVQDLMRTRTSSYRSDDIEHAYTVGSYLHYCGGGFGDIKAEDLSTRKKSGKERMIVGDPLYVITATKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0X7</accession>
    <name>A0AAD8Y0X7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA N(3)-methylcytidine methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_012480</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">S-adenosyl-L-methionine-dependent methyltransferase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the methyltransferase superfamily. METL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1737035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0X7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026113">
        <property type="entry name" value="METTL2/6/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22809">
        <property type="entry name" value="METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22809:SF14">
        <property type="entry name" value="TRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037755">
        <property type="entry name" value="Mettl2_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR037755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1737035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="323" mass="36437" checksum="C5A0AAF545E74094" modified="2024-05-29" version="1">MVEYYDNDFSFEEHQLEMEGKLQSMPSTSETAEQDTIDDDEHVKLHPNTQAQCWDGFHTSHSTGNFFKPRRYIMKCFPCILDHCATEDSTRMGRPKRLVLEVGCGSGSSCLPILRNCAENTIILACDCSAKAVDVCKSVVQSSTDAKNFGAFVSDPSLESDESDTSFAQDVKRAHGQLMEETPTTIDDAVGLADIVLMVFVLSAVPPKRVPRFMKQIFDATKCGGKVCFRDYALYDLPMMRFKETHSVHSTCSDADGRTPRLYERGDGTLSRFFSLDTIRDIFESSGFIMEELRYATVFNDNRKTGERLKRAFVHAVFRKPQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y132</accession>
    <name>A0AAD8Y132_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Conserved virulence factor B-like winged helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011944</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y132"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014464">
        <property type="entry name" value="CvfB_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040764">
        <property type="entry name" value="CvfB_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37296">
        <property type="entry name" value="CONSERVED VIRULENCE FACTOR B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37296:SF1">
        <property type="entry name" value="CONSERVED VIRULENCE FACTOR B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17783">
        <property type="entry name" value="WHD_CvfB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Conserved virulence factor B-like winged helix" evidence="1">
        <location>
            <begin position="181"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="241" mass="26147" checksum="B522912EEE6031FF" modified="2024-05-29" version="1">MLKKYLDCTLFYAIIMSSFLLRRSAVNAFATSFSRHSLSSSSCCAAQRALTTTQAAASSTDNNGGELYQPKFQRGDQIQVEVISFGPLGASVDVIAHKSHDPSDCIPPDEPALGRGMVLQREINYFRRGRGGVDIVKYETLPAYVEKVREQAFEDGDEVEIRLDVSLRPPGGKAKAVDLGEQILQKLKDSDGGVLEVGDKSSPEDINEIFPGASKSAFKKGISALYKRGLVKPGPNSVTLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y202</accession>
    <name>A0AAD8Y202_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011438</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y202"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00136">
        <property type="entry name" value="PDZ_canonical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051647">
        <property type="entry name" value="Mediator_comp_sub12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46007:SF8">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46007">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="82"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="904"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="273"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="121"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="910"/>
            <end position="919"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1199" mass="134300" checksum="9255A0A56B344383" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y250</accession>
    <name>A0AAD8Y250_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011566</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y250"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="174" mass="19067" checksum="DDC7928A5616B121" modified="2024-05-29" version="1">MAERQQSQMSNLEETSNHHEVGFDLENPDRITDASEHEHENDEQYADDDTYTKRSFGCRWVTAAIVVVTILVIFLSSGTFGVAATKNQDVDKEDATTVGGGGDLGKKTSLGGEGNTEVVKIEKDTVEQKAEKAQKTEKSKKSKKSKKGGRSLLGQLSEMAMMEAAFMMVRDDDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2D5</accession>
    <name>A0AAD8Y2D5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011038</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2D5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="331" mass="37776" checksum="D46FE8F38795E7C9" modified="2024-05-29" version="1">MLSSYCRPTSRPPQLTENGFGQEIDNTLSPPQMQTADPVIEEETPAEVAMLLTSIRDISNKEIKDDPPIITALADAFLCFPKLNCAEAEPNQEGHHPLKRPTDFADMFVQHDRKKTRSISMDSPEIHSVDDADSSPLLKWRNIRGESTSPPHGYSIHSTPPPSPRTRSSRRIHLMPRNSRPRAVSCAEAKDHSLLDVTRAECGPDKKLKLILRKKFSWKNYPELEEFLIANREEYLRHSTLNYTMQQKKYNNKLTERMIQLAAEHGYAFDETDFSFVTVRDRIRCYYKSYVQSMKKKGKVIGYAARKAGLVTSEELEESAHTSGKIFVPTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y311</accession>
    <name>A0AAD8Y311_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_011394</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y311"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050966">
        <property type="entry name" value="Glutamyl_endopeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15462:SF19">
        <property type="entry name" value="PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15462">
        <property type="entry name" value="SERINE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="268"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="399"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="408"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="477"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="497"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1738100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="817" mass="91390" checksum="ACA6E068FC85B1BF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y331</accession>
    <name>A0AAD8Y331_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_010958</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y331"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000095">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase GSO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000299">
        <property type="entry name" value="Piriformospora indica-insensitive protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053038">
        <property type="entry name" value="RLP_Defense"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48064">
        <property type="entry name" value="OS01G0750400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48064:SF6">
        <property type="entry name" value="RECEPTOR-LIKE PROTEIN KINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="9">
        <location>
            <begin position="437"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="10"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1738289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="749" mass="83503" checksum="90DDE2F7CA1C0E26" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y440</accession>
    <name>A0AAD8Y440_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010428</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y440"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042243444" evidence="2">
        <location>
            <begin position="20"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="130" mass="13392" checksum="28A5BD29834E3BFE" modified="2024-05-29" version="1">MKFSTVTIIFAISAAGSRSITMVSARADSKAGKSKAPKAKASKVNYHAGGRASYSFSSTLIPTLLPTISPTVSPTVSPTVSPTISPTLSPTVSPTLSPTISPTLSLSMSMVSVRADAKAGKRGKRIRTHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y489</accession>
    <name>A0AAD8Y489_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Enoyl-[acyl-carrier-protein] reductase</fullName>
            <ecNumber evidence="8">1.3.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_010503</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.9" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y489"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004318">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.400">
        <property type="entry name" value="Enoyl acyl carrier protein reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014358">
        <property type="entry name" value="Enoyl-ACP_Rdtase_NADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004957">
        <property type="entry name" value="PRK06300.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43159">
        <property type="entry name" value="ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43159:SF2">
        <property type="entry name" value="ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH], CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1739187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="390" mass="41415" checksum="52F7CC37DDD51015" modified="2024-05-29" version="1">MLRNRSLHFYGKILLPNPSTINTMMFSRNTLLAAAAAFYGASSVSAFAPSTAVGNTVSRSSPAIYTQQTASRQYSSTKLNMSSSVDLKGKVAFIAGVADSSGYGWAISKALADAGATIIVGTWPPVLKIFQMGLKKGSFDDDSTLSDGSKMVIEKVYPLDAVFDSPDDVPDEIKNNKRYSGLDGYTIEEVAKAVEADYGKIDILVHSLANGPEVTKPLLETSRKGYLAASSASAYSAVSLLQKFGPIMNEGGNMLSLTYIASEKVIPGYGGGMSSAKAQLESDTRVLAYEAGRKWGVRVNTISAGPLKSRAASAIGKEPGQKTFIEYAIDYSKANAPLAQDLYNDDVGNSGMFLCSPLARTITGVTLYVDNGLHAMGMAIDSESMSDRNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4Q6</accession>
    <name>A0AAD8Y4Q6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">5'-methylthioadenosine nucleosidase</fullName>
            <ecNumber evidence="3">3.2.2.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.16" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4Q6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008930">
        <property type="term" value="F:methylthioadenosine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09008">
        <property type="entry name" value="MTAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044580">
        <property type="entry name" value="MTAN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46994:SF1">
        <property type="entry name" value="5'-METHYLTHIOADENOSINE NUCLEOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46994">
        <property type="entry name" value="5'-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleoside phosphorylase" evidence="2">
        <location>
            <begin position="364"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="608" mass="67355" checksum="B8A8AC5763A88C1A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4Y4</accession>
    <name>A0AAD8Y4Y4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal RNA large subunit methyltransferase L</fullName>
            <ecNumber evidence="5">2.1.1.173</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_010460</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.173" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4Y4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043527">
        <property type="term" value="C:tRNA methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052915">
        <property type="term" value="F:23S rRNA (guanine(2445)-N(2))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070043">
        <property type="term" value="F:rRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11715">
        <property type="entry name" value="THUMP_AdoMetMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2130.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000241">
        <property type="entry name" value="RlmKL-like_Mtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053943">
        <property type="entry name" value="RlmKL-like_Mtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47313">
        <property type="entry name" value="RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K/L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47313:SF1">
        <property type="entry name" value="RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01170">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01261">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribosomal RNA large subunit methyltransferase K/L-like methyltransferase" evidence="4">
        <location>
            <begin position="371"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="55"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="55"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1739144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="581" mass="64798" checksum="1457CE69CB514255" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5N0</accession>
    <name>A0AAD8Y5N0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heat shock factor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_010020</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5N0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF206">
        <property type="entry name" value="HSF-TYPE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="6">
        <location>
            <begin position="153"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="89"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="91"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1739477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="426" mass="46835" checksum="C4159C6D88CC4D08" modified="2024-05-29" version="1">MASPPTKRCTVTANAADADAAAADQSQSESSTTKDKEMKMMIASGEDIDVKNADATTPPPPSQEAAAAAAAAAAPEGLILLYAASQVETTPKAEAERDVTTEEAPSTIRVFRDGGRGTAEGRYGSSRDAEEASPSNVDGDDSENLAAAAFKNDVKSFPQILQDILATQEYQPIVHWLPDGFSFIIADKQQFSDVILPKCFREALFHSFVRKLNRWGFRRVKSRHKGEESSFANVNFVRDKPWLCLKMKCNSKPTYHKGPSTKKNAAGSANKLAKAARIVVPARAPPRSLSAGGMVDASRAFVATGSRVSVGEYERLPLPKRPIPTVTTAAGSLPAAVASNIQERQHLAFIPPQHHQRIFHERQILIAQMRQRHQLEVEWQRLNAMSSHIDGQFAGRRNINMQSAMMAKYTRDLMSSKNIYYRRERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6A8</accession>
    <name>A0AAD8Y6A8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SEC14 family lipid-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009928</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6A8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008526">
        <property type="term" value="F:phosphatidylinositol transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052578">
        <property type="entry name" value="PI_Transfer_CRAL-TRIO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45824">
        <property type="entry name" value="GH16843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45824:SF29">
        <property type="entry name" value="GH16843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="374"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="568" mass="63462" checksum="AE4075C4FF9E233F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6E0</accession>
    <name>A0AAD8Y6E0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">18S rRNA (Guanine-N(7))-methyltransferase-related protein</fullName>
            <ecNumber evidence="7">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_009608</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6E0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016435">
        <property type="term" value="F:rRNA (guanine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070476">
        <property type="term" value="P:rRNA (guanine-N7)-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039769">
        <property type="entry name" value="Bud23-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022238">
        <property type="entry name" value="Bud23_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12734:SF0">
        <property type="entry name" value="18S RRNA (GUANINE-N(7))-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12734">
        <property type="entry name" value="METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12589">
        <property type="entry name" value="WBS_methylT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="6">
        <location>
            <begin position="53"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23 C-terminal" evidence="5">
        <location>
            <begin position="268"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="91"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="256"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="99"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="116"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="278"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="295"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1739849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="329" mass="36478" checksum="8B4D94A7579FC73D" modified="2024-05-29" version="1">MSRPELTGHASLFYNEKEARKYDSSSRMVGIQREITERAIELLKLPSNRPSFILDVGCGSGLSGQVLEEHGHVWVGCDVSRDMLNMANERIERKREEAMGEGDSSEDDSDNDMNDNNDSNNDFNNSKGGTEESSPGDLLHHDMGTGLPFRPASFDACISISALQWLCYSNTKEQIPKKRLTASSHHYTKGARAVLQFYPESSEHAILISECAAKVGFAGGIVVDYPNSTKAKKHYLVLSFERSYKAPQGLTGLEGALLNEGRSGSGGVRVADKDPRRAAGKKSRGPPRKKKGGGKTKEWILHKKETQRKKGKDTRKDTKFTGRKRPMRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6X2</accession>
    <name>A0AAD8Y6X2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sulfotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009102</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6X2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="511" mass="58409" checksum="91356C1D04ED1D39" modified="2024-05-29" version="1">MNTRFGRRRNNRQQQQQRRSSFVLDRHYFVIQITLVLVTIFCILAWFWIHIATGLRRGDSVDDWSGGRLSSSSVEVVDEDHHSSFADVTAGPEKDVTTIVQEPYETNLRIDAVVAFLMNLAELPPQQLWDTFGMDDDKNDGSNGKKSYGKDPFSLEELEQGHCPSGLNTAEWLPPRPWNSEELSSMFQSKAEELKTDKEARNEETVLIWYEHISKAGGTTFCGLAKTNLGQSLVPKYFCMPKRLDSDLADGRVGSWTNEELIGYTKRESHLLVANEWDPFSHDKLKLSGRTLDGKKFPLDPQHTSPQLLFVTTLRDPLDRLLSAYLFFGAGESPSDFGVWIRRNIGRLPKYRIGEKGAFRCNIARYNVIVWRYSGGNLEHPVSGPSSQQQETQFPLPMTDGEIWRDPFESAIRALSQQDLILPMDIMSKEEGQEAMRRLLGWGKVAIKEGRGKGDRESGHIVTTGKIQNSNAREYLNEEEYRFLWDANWLDNILVLWCRAVFLARLHCNDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7B2</accession>
    <name>A0AAD8Y7B2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009312</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7B2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="123" mass="12466" checksum="86B49B0C9E8A6987" modified="2024-05-29" version="1">MTETKQLEESVTKPPTAGTPANVYDHSAPAATAETKAVDDDVESQKADPVDVVSAYDDKAAKCIGIAMATCIIMGFSLGWIGGAIGYWISFICLIVAIVLASIISCGCCCGSGSSDAAAAALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7G9</accession>
    <name>A0AAD8Y7G9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7G9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35213:SF5">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35213">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="169" mass="19221" checksum="6618443C238B2F0E" modified="2024-05-29" version="1" fragment="single">ALEVLADTASDDELRNRYDASKHSGRSSSENRDHYSTSDTKEDDDSGGRGCSADDDMNSSIRKAASKAKKEGLRKGKWMEEEEEYTTRVIHHFSSGLITLPEGKTLRTFLADKLQCDPMRITKKFAGASCLSKKIHTLCERPQFTPQEIEAARIEIERLEERFKLRLEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y824</accession>
    <name>A0AAD8Y824_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_008850</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45641:SF19">
        <property type="entry name" value="NEPHROCYSTIN-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45641">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="40"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="829"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="871"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="955"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1264"/>
            <end position="1297"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1306"/>
            <end position="1339"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1388"/>
            <end position="1421"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1429"/>
            <end position="1462"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1569"/>
            <end position="1602"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1870"/>
            <end position="1903"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1995"/>
            <end position="2028"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="2333"/>
            <end position="2366"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="2543"/>
            <end position="2576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="188"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="466"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="2346"/>
            <end position="2442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="26"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="102"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="216"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="468"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1740755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2769" mass="310031" checksum="68A349486E1B2A08" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8C9</accession>
    <name>A0AAD8Y8C9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007269</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8C9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="347" mass="39851" checksum="7CAECC8BBBD73B7A" modified="2024-05-29" version="1">MKRSQSPFNCNSIGQSLKRVKISTSPGELRLDKDIEILINENQWTSTLPPQNYVPIEQPTSWRSATISSSRCHGELCHKNARLVRDPVDPLRLRLTCLHQPFSQSLFERWTYLIQMPRMYPHQAPLITRVTREIISNENMARISNVSIGASAAIVASSVMQMHAEPPVPDQILIRSPPPPRNKFDVALNREHSFCENSKFLAIDTETAMFNTWSPISSLGDLLDFLMAIPTKRREWWAVENNRLRHQQHLRLMRTGHEMQSYRTMSAMSNNENMEETAMGCSFLEHQVSSSSRGAESDDDHGEHMMDDSSAYSHATADKLREFPSNRFDVGFPREQSSVPHWDMMQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9M0</accession>
    <name>A0AAD8Y9M0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9M0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00838">
        <property type="entry name" value="MPP_superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="256"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="292"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="357"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="532" mass="57737" checksum="946FC69654463D5B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9X3</accession>
    <name>A0AAD8Y9X3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">SF-assemblin/beta-giardin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_007288</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SF-assemblin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9X3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008374">
        <property type="entry name" value="SF_assemblin/giardin_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40412">
        <property type="entry name" value="SF-ASSEMBLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40412:SF1">
        <property type="entry name" value="SF-ASSEMBLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06705">
        <property type="entry name" value="SF-assemblin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01799">
        <property type="entry name" value="SFASSEMBLIN"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1741715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="277" mass="32137" checksum="D43D08128AA8BA54" modified="2024-05-29" version="1">MAEWTPNRHGGTPNNRGRGDNNAIVEDRPMSPAKKKLSHMVLGDGGFESLMKERSAHRREKEEQSLAQVMIQLTAAERALSTETQRRIESTHAIQKSCTQKIMEMEDNFQRILDERTQRMEERLVSVQEKVEELAVKFDEEREIVPAAMERTGQELLDMVSTFQQELADERNDRLNREGRILAQMDTHASEIISSIEHETNQREQIANNLQERIATNEHLRAQNERDIQDRIQNELSELRGMIDREKQERKMEDDDIVIALNEYTKQLQSSLSVISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAJ4</accession>
    <name>A0AAD8YAJ4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase M17 leucyl aminopeptidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAJ4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042044315" description="Peptidase M17 leucyl aminopeptidase N-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="535" mass="56183" checksum="2C4A3359F5D37819" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAS0</accession>
    <name>A0AAD8YAS0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC1 kinase family protein</fullName>
            <ecNumber evidence="3">2.7.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006375</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.-.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAS0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05121">
        <property type="entry name" value="ABC1_ADCK3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050154">
        <property type="entry name" value="UbiB_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566">
        <property type="entry name" value="CHAPERONE-ACTIVITY OF BC1 COMPLEX CABC1 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566:SF117">
        <property type="entry name" value="UNUSUAL PROTEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="215"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="562" mass="63164" checksum="DDA270257F5FD5A2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAT2</accession>
    <name>A0AAD8YAT2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">fumarylacetoacetase</fullName>
            <ecNumber evidence="5">3.7.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">QTG54_006754</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FAH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.7.1.2" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAT2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004334">
        <property type="term" value="F:fumarylacetoacetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902000">
        <property type="term" value="P:homogentisate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006572">
        <property type="term" value="P:L-tyrosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.230">
        <property type="entry name" value="Fumarylacetoacetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005959">
        <property type="entry name" value="Fumarylacetoacetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015377">
        <property type="entry name" value="Fumarylacetoacetase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036462">
        <property type="entry name" value="Fumarylacetoacetase_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43069">
        <property type="entry name" value="FUMARYLACETOACETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43069:SF2">
        <property type="entry name" value="FUMARYLACETOACETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09298">
        <property type="entry name" value="FAA_hydrolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63433">
        <property type="entry name" value="Fumarylacetoacetate hydrolase, FAH, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="domain" description="Fumarylacetoacetase N-terminal" evidence="17">
        <location>
            <begin position="16"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="16">
        <location>
            <begin position="168"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="325"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="338"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="437"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR605959-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR605959-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR605959-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF09298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1742189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="527" mass="58214" checksum="D6A706089359D046" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YB99</accession>
    <name>A0AAD8YB99_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vam6/VPS39/TRAP1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006964</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YB99"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034058">
        <property type="term" value="P:endosomal vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1480">
        <property type="entry name" value="Coatomer, gamma subunit, appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013041">
        <property type="entry name" value="Clathrin_app_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013040">
        <property type="entry name" value="Coatomer_gsu_app_Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037067">
        <property type="entry name" value="Coatomer_gsu_app_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032914">
        <property type="entry name" value="Vam6/VPS39/TRAP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894">
        <property type="entry name" value="CNH DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894:SF27">
        <property type="entry name" value="TRANSFORMING GROWTH FACTOR-BETA RECEPTOR-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08752">
        <property type="entry name" value="COP-gamma_platf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49348">
        <property type="entry name" value="Clathrin adaptor appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Coatomer gamma subunit appendage Ig-like subdomain" evidence="1">
        <location>
            <begin position="127"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="303" mass="33425" checksum="3C1A620B0F976627" modified="2024-05-29" version="1">MELALEYCDIRHERKEEEGRKVRSTTPSECAYIPLVKVALNADSDPDRGVAAAIQVLALRRNVIDKSAALRLLPKNVPLSEMTRPFLIPAVVENQSQVRRLSVASALLRSRYMQLKKKLTEAQLKSQASLHTVPALQKLNLGEHLHSSKPTKARLVHPASSPNFPEVLLVKHFFSRHLVIQAQVMNVNSSQAYQDDVRTLTGVAFVVAESSDEALLPTLQVPLKTLPPRATGSAWCVLAASPQRLDGTAFLASELRFTVLEVDAAGAPLTFVEANAPGYGRPFVEELQDLEIRHTEFSRGKTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBI5</accession>
    <name>A0AAD8YBI5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dolichyl-P-Man:Man5GlcNAc2-PP-dolichol alpha-1,3-mannosyltransferase</fullName>
            <ecNumber evidence="3">2.4.1.258</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_005723</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate = an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29527"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="Rhea" id="RHEA-COMP:19516"/>
            <dbReference type="Rhea" id="RHEA-COMP:19517"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:132515"/>
            <dbReference type="ChEBI" id="CHEBI:132516"/>
            <dbReference type="EC" id="2.4.1.258"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:29528"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.258" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBI5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052925">
        <property type="term" value="F:dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007873">
        <property type="entry name" value="Glycosyltransferase_ALG3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12646:SF0">
        <property type="entry name" value="DOL-P-MAN:MAN(5)GLCNAC(2)-PP-DOL ALPHA-1,3-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12646">
        <property type="entry name" value="NOT56 - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05208">
        <property type="entry name" value="ALG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="199"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="341"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="368"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="399"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1743102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="457" mass="52277" checksum="5F697D101AD9595B" modified="2024-05-29" version="1">MWTKLYHNLAKPRYDHVWIVLLLIAEALLSTLIVKRVPYTEIDWVAYMQEVTTYQNGERDYINIRGDTGPLVYPAGFLYLYGFFKDIATRSIDTTDPTGLGGSTSPEAVRIIQWVFVVLYVINSAVVLMLYNAVLQRMRQQQNAQSSTATMVWYWRIAMGITCLSKRVHSIFVLRLFNDAPAMILLHISMYLFACCDSWALGCVVFSLAVSIKMNVLLFAPGLLLLLLQKNQSLFGTIQHLSICASIQLFLGWPFLTTYPISYIKKAFEFDRVFFYKWTVNWKFLPEEIFTSKPWALILLACHLGVLGMLANKWWQSSISQLGDANARKPMRWTKCNKDKIRLSPEYVIFTMFASNYVGIVFARTLHYQFYCWYFYSLPMLLWLTSFGPSSSGDKFSKVVLPLVANVLAVAGVEYAFNVFPATELSSAALQMSHAYLLLKVVSSQVPSIQIDKEKMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBS3</accession>
    <name>A0AAD8YBS3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006242</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBS3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="75"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="148"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1742645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="315" mass="35091" checksum="3C4CB4098B727F80" modified="2024-05-29" version="1">MRSEDGEIADMMCCVSCGTADVNNIKLKEYNLLDGSAACQKDHTSQQERDCESRATEIHDDILFRQPESSHLGECPICLLPLSLDTKHAMMQSCCSKLICIGCYCASIRYEVVKVIKRRSCPFCRQPEPESAAEIEHYKMKRRKANDPVAIQGAGKRCYHDGDYERAFEYFSKAIAIEAGDAEAEAHYCLSFMYRDGKGIGRDAQKRLYHLEEAAIGGHTKARHDLGVHEVYQGRIERAARHFIISANLGHDASLKALRELRAAGGVSCDDFATAFRAHQAAVNATKSRQRAEAFAIGAIQIVGKSRRRREANGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBT6</accession>
    <name>A0AAD8YBT6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DNA topoisomerase 2</fullName>
            <ecNumber evidence="14">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">QTG54_007132</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13 14">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="14">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Plastid</location>
            <location evidence="4">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 14">Belongs to the type II topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="14"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
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        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
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    </dbReference>
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        <property type="entry name" value="Topoisomerase II, domain 5"/>
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        <property type="entry name" value="DNA_Topoisomerase_II"/>
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    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
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    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
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    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001241">
        <property type="entry name" value="Topo_IIA"/>
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    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013759">
        <property type="entry name" value="Topo_IIA_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013506">
        <property type="entry name" value="Topo_IIA_bsu_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
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    <dbReference type="InterPro" id="IPR001154">
        <property type="entry name" value="TopoII_euk"/>
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    <dbReference type="InterPro" id="IPR018522">
        <property type="entry name" value="TopoIIA_CS"/>
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    <dbReference type="InterPro" id="IPR031660">
        <property type="entry name" value="TOPRIM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034157">
        <property type="entry name" value="TOPRIM_TopoII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10169:SF38">
        <property type="entry name" value="DNA TOPOISOMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10169">
        <property type="entry name" value="DNA TOPOISOMERASE/GYRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00204">
        <property type="entry name" value="DNA_gyraseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16898">
        <property type="entry name" value="TOPRIM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01158">
        <property type="entry name" value="TOPISMRASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00418">
        <property type="entry name" value="TPI2FAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00433">
        <property type="entry name" value="TOP2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="Type II DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52040">
        <property type="entry name" value="TOPO_IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00177">
        <property type="entry name" value="TOPOISOMERASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11 13 14" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12 13 14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 13 14" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="17">
        <location>
            <begin position="481"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="domain" description="Topo IIA-type catalytic" evidence="18">
        <location>
            <begin position="754"/>
            <end position="1205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="30"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1131"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1245"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1319"/>
            <end position="1400"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="1074"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="1137"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="1258"/>
            <end position="1271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="1278"/>
            <end position="1288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1327"/>
            <end position="1345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="1346"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="1367"/>
            <end position="1378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1379"/>
            <end position="1398"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="13">
        <location>
            <position position="844"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="19">
        <location>
            <position position="1423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00011080"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU362094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS52040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK1742567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1423" mass="158443" checksum="BBAF136DD6B58AFC" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD11</accession>
    <name>A0AAD8YD11_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CTP synthase</fullName>
            <ecNumber evidence="9">6.3.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">UTP--ammonia ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_005833</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>UTP + L-glutamine + ATP + H2O = CTP + L-glutamate + ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:26426"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the CTP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.2" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD11"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003883">
        <property type="term" value="F:CTP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019856">
        <property type="term" value="P:pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03113">
        <property type="entry name" value="CTPS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01746">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000207">
        <property type="entry name" value="CTP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000002">
        <property type="entry name" value="CTP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01227">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004468">
        <property type="entry name" value="CTP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017456">
        <property type="entry name" value="CTP_synthase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033828">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003792">
        <property type="entry name" value="PRK05380.1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550">
        <property type="entry name" value="CTP SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550:SF0">
        <property type="entry name" value="CTP SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06418">
        <property type="entry name" value="CTP_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3 9 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CTP synthase N-terminal" evidence="11">
        <location>
            <begin position="77"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase" evidence="10">
        <location>
            <begin position="412"/>
            <end position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU810713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1743212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="668" mass="74008" checksum="FF4048156EFE8DB3" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDD3</accession>
    <name>A0AAD8YDD3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004706</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDD3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="180" mass="20346" checksum="F85B46A8F8A3DD83" modified="2024-05-29" version="1">MREKRVLQSASIRGIGFKKFYSLGPSSKRHFMLTGWALCNKQRGDEDYNTIRTKVLQSLSFIKAHLASQETFKDKLASVEKHSLSLTEKRVLDESREQVARADAVINAFDAHDVNAIKSQYVCQVLLHKSARHFEHLAHSGLVTEREASVFLERFGEELNQLRLSSELQASSSPDLDSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDI5</accession>
    <name>A0AAD8YDI5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyltransferase (Family 90)</fullName>
            <ecNumber evidence="1">2.4.2.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_006136</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.-" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDI5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF35">
        <property type="entry name" value="PROTEIN O-GLUCOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1743515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="486" mass="54641" checksum="CC538D5019B47B89" modified="2024-05-29" version="1" fragment="single">MIRRRRRSAGAVMSLAVLAAICLPAALFHLKRSDTDDASRNHRHLSILAQRKDDQHIPNDEVILSLLKAFDENGAPIPPTQISPYTLDDVISILPTFEAVFGVVIYDPSTDKFILHYSNNMRWKGGCHKLVGSFQTLAHSLRTMFPERFATGSGQPELALAIASGDYPEVNLGSASSFATIRRNRNCFIEGTSACVPSDLAPVLQFGSAFKSPKIFPSMIAMPMPQNNHVACFETYAAHQEICRMHLPRDKYSPRGLVFEETVGVGWDDLIPSVVWRGTDFSYLHRFYPRLRQPDFEMDVGSKLEMLRSKLSQPPATHLTTIMSHDNVKVAATLAMREVYDQLIPRWRSVIWTAEAEREAEEKQKALPKDSKEVVVPWANMKFASAMHAGFKTPPSKIPYYQEFEEHGIPAGGEGMSLETLARYKYHIDIGGGGGTTWSGTLEKLGLPGLLFHHETPMKDYLHDKMVKWVHYVPVKEDLSDLKEKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDX4</accession>
    <name>A0AAD8YDX4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDX4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="110" mass="12288" checksum="BC297C86CF1BFAFB" modified="2024-05-29" version="1">MPPNNRGQHKPSPPVNNQRRIFRGTGGPTDGNLPPKKTPRVRVKYQHQAASADDNVQLSNNNEDGTDLEEHADVDVNQLSLNDDGNNDRLNNNNHDSVAKKKKTTTIHYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YF50</accession>
    <name>A0AAD8YF50_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_003999</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YF50"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="341" mass="37717" checksum="61E253CA098F568D" modified="2024-05-29" version="1">MSSTPSIEVQRFGGALLMRFAGSTLAAFALLLVLSHKSYVNETDQQQPTSNGLRSLQWQDEAGEEDRYLPYRHHPHQHSSVNTGLDSSVVSEPSSKDYFVFLQKFPLQNSFKMIFHTEVVVCPRQAFAKDAHFLESLDALVLELPPSSFDDIIINKKAKKQIHFAVVAKNQWSAQSDPSCVQLGYGGKSDWSSVDNAYEFCRTACCGSPHKNDNSNYALNSLDAVIKNAMGEEKEVYLYGVSSMSGEDAYRAVCHGHMNAVEEDELPMCVSNWAGTDYNALTNNCNTFTSTVLKCVYGMSDSKPDLGVSDMVKVSCPKEKSNDKDVQMCKVPKSANILSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFM2</accession>
    <name>A0AAD8YFM2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GrpE protein homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_003565</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the GrpE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFM2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001405">
        <property type="term" value="C:PAM complex, Tim23 associated import motor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00446">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.22.10:FF:000002">
        <property type="entry name" value="GrpE protein homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.22.10">
        <property type="entry name" value="Head domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01151">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000740">
        <property type="entry name" value="GrpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013805">
        <property type="entry name" value="GrpE_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009012">
        <property type="entry name" value="GrpE_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237">
        <property type="entry name" value="GRPE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237:SF23">
        <property type="entry name" value="GRPE PROTEIN HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01025">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00773">
        <property type="entry name" value="GRPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58014">
        <property type="entry name" value="Coiled-coil domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51064">
        <property type="entry name" value="Head domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01071">
        <property type="entry name" value="GRPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="64"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="71"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1745641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="254" mass="27789" checksum="26E2D0F05F67DB9F" modified="2024-05-29" version="1">MSLRSRSIHIARAALTKELQLSSTSASSVQRAWQQSLVQNNTNTSMASSSYSVDFSSVRSFSSKPADAASEEPKDASTDKADETAAAEETAENSESTKVAELEQQVKDLKDNLLRSLAEQENTRRIAKRDVEQARSFAIGSFAKSLLETSDNLSRALDAVPEELRHDHDHHSVLATLYEGITMTDDGLSKAFKKNGLEKFGMPGEKFDPNIHEALFEYPDPNGEAGNIGQVMKKGFMLNSRVLRPAEVGVVKAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFT5</accession>
    <name>A0AAD8YFT5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2-isopropylmalate synthase</fullName>
            <ecNumber evidence="3">2.3.3.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.13" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFT5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003852">
        <property type="term" value="F:2-isopropylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:L-leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.260:FF:000001">
        <property type="entry name" value="2-isopropylmalate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050073">
        <property type="entry name" value="2-IPM_HCS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013709">
        <property type="entry name" value="2-isopropylmalate_synth_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054691">
        <property type="entry name" value="LeuA/HCS_post-cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036230">
        <property type="entry name" value="LeuA_allosteric_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10277:SF9">
        <property type="entry name" value="2-ISOPROPYLMALATE SYNTHASE 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10277">
        <property type="entry name" value="HOMOCITRATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22617">
        <property type="entry name" value="HCS_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08502">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00917">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110921">
        <property type="entry name" value="2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="2-isopropylmalate synthase LeuA allosteric (dimerisation)" evidence="2">
        <location>
            <begin position="105"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="287" mass="30378" checksum="B5BFD49442A30DED" modified="2024-05-29" version="1">MVAEYTGMKCQPHKAIVGANAFQHESGIHQDGMIKDKSTYEIMTPESIGLMRGESQSGAGIVLGKHSGRNAVGTRLRELGYDLDLDKLNAVFARFKEVAEKKKGGLDDDDLESLVSDQSGSMNELWKVTGLQATTGLSGIPTATVKLMGPDGVERYVSSTGTGPVDAVYKAIDQIIGVEVTLESYAMNSVNEGIEALASTRVVVVPTMDGPNDSAVMDAQTSQLREKKFSGSGSDTDIITSSARAYVSALNKLLTWKMRRMANGADQTGAKDAVAVDGEAPLVVGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFV5</accession>
    <name>A0AAD8YFV5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein kinase-like domain superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004808</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFV5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="95"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="465" mass="52405" checksum="EEFB94E1998E5E2B" modified="2024-05-29" version="1">MTDPLIEIEDDKQKKTELMKRVFAEKAASSSVELFQRIDRACKEGGKIEAVTLSGGYTNYSYKLFVPGQPDLAVFAKLSFEYALWNPDKNAHYDLQRTVCEYEVMSKMAEKTPECVVAPLACYDIEDEGQKMKLLVTEWSKADEQLCNQFIDGAVDTRIAPKLASTLATLHTIDFDPDFNEQVKPCMLSLFDQMIAYVKITCEELKPKDRTEKHMVILGSELMLKTVEANLADCSTRDCLIHSDSHAFNIIVEAKPSIEELENFGPNGNFVLVDWEMCMAGPKGRDVGLALSFPIGCMVAHALGGHLDANESINAFIISLLDSYAACMSEAGKSPEEVASIIRNVTGWVGCFQFLAFYFLDVQMVDFPCETEHDRKYVKDAMGVLGLKLLRLSYDTDYFPEGATTEQVKNMFLSLVEEEVTETAHERLMHRRRRQPRKSSMLRASNRRVSDAMLNFSARELSITE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGP3</accession>
    <name>A0AAD8YGP3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002866</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGP3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="214" mass="24035" checksum="5ADE18925014E823" modified="2024-05-29" version="1">MNDDTNDQRQWKEGVNISGMSSKAVHRSRGDEDAKSFDAFDEMVAEIEEEEIRLDSALFGSKSQSRQSEHLLNKRKEGDMHKKRETCNHNSSLSRHTTKVICLKWVDRRGMVGHFTGEVNSMIQPHGKGILVYENGLVLDCNWCNGTPSAGINDDTAATSQKGHAAVVSEEKSNQFLPDYDLGMAARSRYDMKEEDPDKAIEGISRLKKLDFAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHC6</accession>
    <name>A0AAD8YHC6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002635</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHC6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="476" mass="54305" checksum="DEFD797F35CBA3D7" modified="2024-05-29" version="1">MNMSDFYSAHSLFNHGISYLRRGHWNKHYDLSLEFTLSSLNEELPSVVTSATIKQYVDNKKAQLATLSDDTLLNYPAMVIPSKILAVQLLVKLQVSLAIIGEGAAMTIIPLKVIQMSLTYGMSSYSPSAFAQYGNYLALIGDDFEEGCRYVKFALSLMKKVPSRAHDGITMFYSNHTKLYVEPMQSSIECYLDARKACLKSGIPFALSCSYTYNNLCLWSGKELNAVVVSMSDMIRESKYLKNFAILTIVLPMFRFAMRLIGQLDAPAPQQDEGGNAYAFHLHDMFLTKLSEAFIFRELNKARDSAGKYFSIYCTQTNTMRWCVLRRLSPPATFFGRFYFGLVSFWVAREMNDKKKSKKWIQRGVECKDEIEKLSVLASTWNFQNKAYLLQAEEQFSSMNFDLAERLYDDAISSSKTHKFVNEEALANELAGHFYLETGRRNRSVHYFSQAFEKYNEWGAVAKANTLAAYLDESDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHJ6</accession>
    <name>A0AAD8YHJ6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glucokinase</fullName>
            <ecNumber evidence="3">2.7.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003268</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.2" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHJ6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005536">
        <property type="term" value="F:D-glucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004340">
        <property type="term" value="F:glucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd24008">
        <property type="entry name" value="ASKHA_NBD_GLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.367.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003836">
        <property type="entry name" value="Glucokinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47363">
        <property type="entry name" value="GLUCOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47363:SF1">
        <property type="entry name" value="GLUCOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02685">
        <property type="entry name" value="Glucokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="424" mass="45661" checksum="D239166584FE260E" modified="2024-05-29" version="1">MSHSSWCTAGGSGKGVCPFSVALFAGSAFSYLNYVRLRSKSAVAKCCIDEHKQTYIIAGDIGGTNSRFALHRPGQKDPLLVHIYPNEEALKTAPTYHHATLMPFLKKCLAEVDEWKALGEKEVLSQIQIVGCLATAGPVTTNNDVFMVNLGENGGSIDGNEIEQCQDGLLSLVVRCKLVNDFVGQGYGVLDLDYDKEVIELLPGSKAKMNDLAPICCVGAGTGLGECFLTKSSLATKLGYECYPSEGGHADYVPRGPLEVELLDYLKRKFSSDHRISVERVVSGRGLANVYEFLAQKFPTKVDKSVHEEFLNAGDQQGRVIGVNSSTKGSLAQQAVQIMCAAYGSEVGNAALKFIPTGGMFVTGGLAPKNIGMIQGEDSPFMKAYLDKGRMNGLIESIPIFAVMNEDVGLRGARVCAEREYNAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHX7</accession>
    <name>A0AAD8YHX7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6824 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003788</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHX7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049227">
        <property type="entry name" value="DUF6824"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20710">
        <property type="entry name" value="DUF6824"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6824" evidence="2">
        <location>
            <begin position="11"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="242" mass="27168" checksum="13F5B87D4722130D" modified="2024-05-29" version="1">MNMEMKPTQTDVLSGRGVSTNNHKGNENFRNIIIDQMDTYAASTKSQKMAISKDVVHRLHNNFTPPGRFLKKDSETKQWVELTMKEATGKTAQAFAYAIRDRRKIKEENQKHEKTEEPATRLSGTKRPASSLDFANEGHSSASTLTHSDEKGKASKQTKTQNKSTGAQSSGTIGRAAAAPGFFTEFFTNPINLVIRRGFNNQQLLRPQVQPNLQQQTLMQQVNTIAEFLRRQQDGNDEQKEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIK7</accession>
    <name>A0AAD8YIK7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GRIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_002277</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIK7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000237">
        <property type="entry name" value="GRIP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18921">
        <property type="entry name" value="MYOSIN HEAVY CHAIN - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18921:SF2">
        <property type="entry name" value="THYROID RECEPTOR-INTERACTING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50913">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GRIP" evidence="5">
        <location>
            <begin position="103"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="79"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1746933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="207" mass="22949" checksum="E8F59AA59BEE7B29" modified="2024-05-29" version="1">MANENLQTALESFQNERDAEIALLLEQRAAAEDAIAAAHEASLEAMREANVQQMRDVQYAADKSVQNTLTEMDKMEVTIQDCRKDNLNLRKALDEAISQLQRNQEDVIDRSLIKNVILDWHGKKGKAKRDVMILLGSILHFTEDEKDKAFIGEGHGTLGKVVDAVAAPLPPAKLNVDKIEGDTVREKWVNFLLAETGEDGSNEDAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJI4</accession>
    <name>A0AAD8YJI4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJI4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="134" mass="14598" checksum="2003F1ADD5339013" modified="2024-05-29" version="1">MTDNNAPKTPATMHEMDERSMPAWVLSFSAAMVPFCAFCYGHSRGVTTRVVERVVKSPVGVYGLLALPFLTLGMEKSIYDTVQSWQGLDPNVVPADRGGFPSGGSALPSFSLIPVRKIARRLTQAAIEQNEPKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJK7</accession>
    <name>A0AAD8YJK7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RWD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJK7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RWD" evidence="1">
        <location>
            <begin position="20"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="217" mass="23646" checksum="04849E615B845A20" modified="2024-05-29" version="1">MVGVEETASGILDALDRVVLEVEAMDAICNADTEENDDKDFVVSQQALGQAQTCLDEANASDAPSQIDIEAFVRTEACDGNTSNDGVRLRMSLPLGYPTIHSASVTVVHTPKFVTRSNHDTLSSKLQAIANELIGSEAMMSIISECRNIVSDWECNSSDNIDAIPSEAEEDDVVTSLPNNPACISRRWIWVHHIHEEFSGLKIQINPKYGAHSFQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJR4</accession>
    <name>A0AAD8YJR4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA pseudouridine(55) synthase</fullName>
            <ecNumber evidence="2">5.4.99.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_001340</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase Pus10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJR4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160148">
        <property type="term" value="F:tRNA pseudouridine(55) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.3190:FF:000001">
        <property type="entry name" value="tRNA pseudouridine synthase Pus10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039894">
        <property type="entry name" value="Pus10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048741">
        <property type="entry name" value="Pus10-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21568">
        <property type="entry name" value="TRNA PSEUDOURIDINE SYNTHASE PUS10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21568:SF0">
        <property type="entry name" value="TRNA PSEUDOURIDINE SYNTHASE PUS10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21238">
        <property type="entry name" value="Pus10_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pus10-like C-terminal" evidence="5">
        <location>
            <begin position="37"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF21238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1747377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="183" mass="20555" checksum="EECDA9E4F6AA7B47" modified="2024-05-29" version="1">MMEERGNCHDINGWPQSLVGNDRFHGSNLNGVGVSSPLELTSSSSFSGLQAETEEKVKHYGCICWTSVIIRSDQELVEKLGCLPWDQEENSDDQCNIFPLEIKQDTPLRVLHRRSSDTRTRQILSLSARRINDHWIQLRMATSAGTYVKEFCHGDCGRTQPSISSLLGGRVDITELDCEGIEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJT1</accession>
    <name>A0AAD8YJT1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJT1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36970:SF1">
        <property type="entry name" value="BESTROPHIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36970">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="425"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="500"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="555"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="585"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="604"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="627" mass="70205" checksum="81C48CD350DD5FEF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLA8</accession>
    <name>A0AAD8YLA8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Spliceosome associated factor 3b, subunit 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_001582</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RSE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:nucleic acid binding"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="P:mRNA processing"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Splicing factor 3b subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
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        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_2nd"/>
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        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
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        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
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    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Beta-prop_RSE1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="9">
        <location>
            <begin position="77"/>
            <end position="444"/>
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    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="10">
        <location>
            <begin position="545"/>
            <end position="871"/>
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    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="8">
        <location>
            <begin position="1009"/>
            <end position="1327"/>
        </location>
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        <location>
            <begin position="951"/>
            <end position="1000"/>
        </location>
    </feature>
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        <location>
            <begin position="960"/>
            <end position="973"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1747619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1360" mass="147096" checksum="849EC37AC350C4E7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLS5</accession>
    <name>A0AAD8YLS5_9STRA</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000672</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
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            <taxon>Eukaryota</taxon>
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            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLS5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159">
        <property type="entry name" value="CENTROSOMAL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159:SF60">
        <property type="entry name" value="SPINDLE ASSEMBLY ABNORMAL PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="345"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="521"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1037"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1144"/>
            <end position="1202"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="392"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="553"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="638"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="794"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="988"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1082"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="130"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="189"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="205"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="233"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="277"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="345"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="521"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="535"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1037"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1191"/>
            <end position="1202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1202" mass="133728" checksum="33701A6F82F504FC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YNL5</accession>
    <name>A0AAD8YNL5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Mechanosensitive ion channel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_000599</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YNL5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006820">
        <property type="term" value="P:monoatomic anion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016688">
        <property type="entry name" value="MscS-like_plants/fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31618:SF1">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31618">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="470"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="520"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="838"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="870"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="domain" description="Mechanosensitive ion channel MscS" evidence="5">
        <location>
            <begin position="883"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="118"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="244"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="607"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="77"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="137"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="153"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="193"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="244"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="283"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="607"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="647"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="664"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1748660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1111" mass="122724" checksum="DFEA402F2AD386AE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPC7</accession>
    <name>A0AAD8YPC7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">dihydroxy-acid dehydratase</fullName>
            <ecNumber evidence="14">4.2.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">QTG54_000881</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:24809"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:24810"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate = (S)-3-methyl-2-oxopentanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:27694"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:27695"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="13">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 3/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IlvD/Edd family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.9" evidence="14"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPC7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004160">
        <property type="term" value="F:dihydroxy-acid dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009082">
        <property type="term" value="P:branched-chain amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.30.80:FF:000001">
        <property type="entry name" value="Dihydroxy-acid dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.80">
        <property type="entry name" value="IlvD/EDD C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00012">
        <property type="entry name" value="IlvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050165">
        <property type="entry name" value="DHAD_IlvD/Edd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042096">
        <property type="entry name" value="Dihydro-acid_dehy_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004404">
        <property type="entry name" value="DihydroxyA_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020558">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056740">
        <property type="entry name" value="ILV_EDD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000581">
        <property type="entry name" value="ILV_EDD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037237">
        <property type="entry name" value="IlvD/EDD_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00110">
        <property type="entry name" value="ilvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002068">
        <property type="entry name" value="PRK00911.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21000">
        <property type="entry name" value="DIHYDROXY-ACID DEHYDRATASE DAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21000:SF5">
        <property type="entry name" value="DIHYDROXY-ACID DEHYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24877">
        <property type="entry name" value="ILV_EDD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00920">
        <property type="entry name" value="ILVD_EDD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143975">
        <property type="entry name" value="IlvD/EDD N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00886">
        <property type="entry name" value="ILVD_EDD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00887">
        <property type="entry name" value="ILVD_EDD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 20" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="17" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042206172" description="dihydroxy-acid dehydratase" evidence="17">
        <location>
            <begin position="20"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="domain" description="Dihydroxy-acid/6-phosphogluconate dehydratase N-terminal" evidence="18">
        <location>
            <begin position="76"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Dihydroxy-acid/6-phosphogluconate dehydratase C-terminal" evidence="19">
        <location>
            <begin position="410"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00052865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF24877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAK1748942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="638" mass="68317" checksum="DF62437FBDCF7F41" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPE7</accession>
    <name>A0AAD8YPE7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH:ubiquinone oxidoreductase intermediate-associated protein 30 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000911</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPE7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042145004" description="NADH:ubiquinone oxidoreductase intermediate-associated protein 30 domain-containing protein" evidence="2">
        <location>
            <begin position="32"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="370" mass="42054" checksum="348949EE66C74358" modified="2024-05-29" version="1">MMCWKIQAQTIISRRLCFLVLIGNVLLVAQANIPTGPHSGNKSNTYSTNNDEEDIPIISDQFQHRRSNNERRRSGRSSGIDSRRSRTRRRRHEDNGGSESDVDDDIPSFSFFSDDEYDDMGYERERIRQRRSRLRKRRNQYTQDDDQSKVMFGLGAHIDSLRSWTESKTGVRIPRINIHCDPVTILKIRKAWSVPGVIFRVGADFETYRLSGGCWRFRACCEDKLIHGRFTIKEVQSNDDEDDNDVLIEYSKSWMFANTVGAATRFNLCAAYSILQKSGGVRFGILTENNAGAIGRVTSSPFNGNQRFSVIPVLKLDEEERFKVEVKTNVDVPNPELVLGMDLEGRSGSVIGIAGSIDIEVEELNLIANF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3C6</accession>
    <name>A0AAD9D3C6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">formate--tetrahydrofolate ligase</fullName>
            <ecNumber evidence="2">6.3.4.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_016906</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.3" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000068">
        <property type="protein sequence ID" value="KAK1732371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3C6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004329">
        <property type="term" value="F:formate-tetrahydrofolate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00477">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001123">
        <property type="entry name" value="C-1-tetrahydrofolate synthase, cytoplasmic isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001741">
        <property type="entry name" value="Formate--tetrahydrofolate ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.410.10:FF:000001">
        <property type="entry name" value="Putative formate--tetrahydrofolate ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1510.10">
        <property type="entry name" value="Domain 2, N(10)-formyltetrahydrofolate synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.410.10">
        <property type="entry name" value="Formyltetrahydrofolate synthetase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01543">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000559">
        <property type="entry name" value="Formate_THF_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020628">
        <property type="entry name" value="Formate_THF_ligase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01268">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00721">
        <property type="entry name" value="FTHFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00722">
        <property type="entry name" value="FTHFS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1732371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="653" mass="69780" checksum="DFD3132FADB2E1D1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4Y7</accession>
    <name>A0AAD9D4Y7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_015235</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1733977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4Y7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000400">
        <property type="entry name" value="Nuclear pore complex protein NUP107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013210">
        <property type="entry name" value="LRR_N_plant-typ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48065:SF75">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING N-TERMINAL PLANT-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48065">
        <property type="entry name" value="OS10G0469600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08263">
        <property type="entry name" value="LRRNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="500"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="549"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="590"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="domain" description="Leucine-rich repeat-containing N-terminal plant-type" evidence="8">
        <location>
            <begin position="254"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="85"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="176"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="693"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="105"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1733977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="751" mass="84190" checksum="B3616000BCCD82ED" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5M6</accession>
    <name>A0AAD9D5M6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Smr domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015416</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5M6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="145" mass="16041" checksum="0135DA0B6C5EB084" modified="2024-05-29" version="1">MLSLVFDEANLQFKKIRQHLNSLALEQTPPKSKSASPQAHVSEPKSAPSDISSLSLDNKAIKTRFSILAGEVSNLYKSTKPSKKMKAQATRESITIDLHGYTKEAAVEMLDASLPSWIDTAMHGEYPFVVHVTIIVVLVVKCYQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6G2</accession>
    <name>A0AAD9D6G2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GST N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014496</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6G2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="8"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="157" mass="17712" checksum="19F70E52A8BB2427" modified="2024-05-29" version="1">MGGTTQTKKCFFYDVKHSNNSARVRLWLKVHGGLGDHIETVTLTHADLDGGGKLVEVNPLKKVPAFLTDNGLKLFESFVILSYLEDRFGDGRFILANVEDRALVQLFVRIHDIYISSPNCTQSNFSHTQGCMYLDPYPTNIHQKEEQCPILLYAPPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6H5</accession>
    <name>A0AAD9D6H5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">18S rRNA aminocarboxypropyltransferase</fullName>
            <ecNumber evidence="6">2.5.1.157</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_014602</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>an N(1)-methylpseudouridine in rRNA + S-adenosyl-L-methionine = N(1)-methyl-N(3)-[(3S)-3-amino-3-carboxypropyl]pseudouridine in rRNA + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:63296"/>
            <dbReference type="Rhea" id="RHEA-COMP:11634"/>
            <dbReference type="Rhea" id="RHEA-COMP:16310"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74890"/>
            <dbReference type="ChEBI" id="CHEBI:146234"/>
            <dbReference type="EC" id="2.5.1.157"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TDD superfamily. TSR3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.157" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6H5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106388">
        <property type="term" value="F:rRNA small subunit aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01116">
        <property type="entry name" value="TSR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007209">
        <property type="entry name" value="RNaseL-inhib-like_metal-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022968">
        <property type="entry name" value="Tsr3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007177">
        <property type="entry name" value="Tsr3_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002621">
        <property type="entry name" value="PRK02287.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20426:SF0">
        <property type="entry name" value="18S RRNA AMINOCARBOXYPROPYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20426">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN TSR3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04068">
        <property type="entry name" value="Fer4_RLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04034">
        <property type="entry name" value="Ribo_biogen_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNase L inhibitor RLI-like possible metal-binding" evidence="9">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="16S/18S rRNA aminocarboxypropyltransferase Tsr3 C-terminal" evidence="8">
        <location>
            <begin position="85"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="231"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="239"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="267"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="330"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1734729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="361" mass="40829" checksum="941FB8DB6CB52126" modified="2024-05-29" version="1">MPRNRVHNKGGNQRRRPRPNAYDDTSEPAMCLPTNEDDAKDNPLKGLQLRMWDFAQCDPKRCTGARLARRGIFRPMPLKQPFRGIVLSPNGTVSVSPADRHIVEEMGLSVIDCSWARLAEIPFKQMRSGHHRLLPFLVAANQVNYGKPSKLSCAEAAAATLYICGYVDAAKAVLDEFGWGREFIKLNKELLELYRTSADADEVVKRQNDWLKEVEDANGKAGAGHLFGKKKNKTWGKEDSDEEEGSEEEDEEEIPAFGRGEMGELPPSDDEYEEYYSDDDEPKMDKFGNYIVDEDDSNDEPKMDKFGNYIVDEDDSDEEPKMDKFGNYIVDDDNAEEDESNSDEAEMSMKEVGDAIEQLDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6J9</accession>
    <name>A0AAD9D6J9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NRAMP family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_013152</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6J9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015086">
        <property type="term" value="F:cadmium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034755">
        <property type="term" value="P:iron ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001046">
        <property type="entry name" value="NRAMP_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF037982">
        <property type="entry name" value="Nramp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11706:SF33">
        <property type="entry name" value="NATURAL RESISTANCE-ASSOCIATED MACROPHAGE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11706">
        <property type="entry name" value="SOLUTE CARRIER PROTEIN FAMILY 11 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01566">
        <property type="entry name" value="Nramp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00447">
        <property type="entry name" value="NATRESASSCMP"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1736016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="380" mass="41267" checksum="9CEB4DAAD157D990" modified="2024-05-29" version="1">MSIRGTYANKNSLLALGSASQASTSNAIIKRDADNDSGEEKQNNASLWQPSGSYLKDFLFFSGPGWFVSIAYVDPGNYQADIQAGATSQYSLLFALWWTGILSIYVQILCVRLAFYGKLTLSQAQAQNSTKTSRYFHWAIAEFSTIITDLPGVIGFAIALNYFFGWPYYVGVLLSLLTTMMFLATLNLSGGMRILEIAIAIFVAVMSVALFVEMDFVNPDVGALLKGWGYGFVDVNSSDIFSIAGILGSVVMPHNLYLHTAAVQSKSEQVNQSPDVIHSAVKYCSVEPILPILISFFVNMAVISIAAESVYGQTDDAEQVGITDFCSYFQSLKGGCLLWAIALLAAGQSGAITTTYTGQYVMDGFLNLQIPIAVRSILRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6Y2</accession>
    <name>A0AAD9D6Y2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">H15 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6Y2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005818">
        <property type="entry name" value="Histone_H1/H5_H15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00538">
        <property type="entry name" value="Linker_histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51504">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="H15" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="99" mass="11280" checksum="AD6849027E80B632" modified="2024-05-29" version="1" fragment="single">MPYGSAIIAAIESLKDHETGSPISSIRRHILDDTNDNNSDDPSWNEVHFQKTLKTLVEKGGLLQINGINYKFSDQYLQRRVETLRARAESIEEQTYKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7G6</accession>
    <name>A0AAD9D7G6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1737006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7G6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042270647" description="Peptidase A1 domain-containing protein" evidence="1">
        <location>
            <begin position="32"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="429" mass="47170" checksum="A83C4CC407D1C134" modified="2024-05-29" version="1">MIGRDRPLARQAIPSLCIALLLLCTFTTTYSFVSTTAACNKKLRSHQPTTLSVHCVQNNNSTHVLTRRSSIITSSIAIASSCLFPQLPSSAADIDVVTTTEQQSTAARPSITIPLKYEPKLCAYTVSYVVGDTKFGAIVDTGSPFLVVPQTSCRPDYKWGCYRAEESQPSGLEPTYERFVGNEGMMEWREGKFSFANSIAMVSSFALLFPQSSSMVFGVVSESLLDGSGGLFLGLVKETNSWIRPSFLGQSDVGAFSVDLREREGFDKSLTLYGGSRQPQQKFSNPSYAIPLVRDLNKRFGDATIHYVGVASSLIVNGNNLATSSRRNKIYVIFDTGCTGMSISTSLFNERYSIARERRENNLWGNVELQFNTVSGGMASLNAKKPLTTTLDDRPWGKKLDGHLIVLGLAFLEGHEMTVDIDNDKIWFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7J4</accession>
    <name>A0AAD9D7J4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_013470</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7J4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36367">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36367:SF2">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042025325" evidence="3">
        <location>
            <begin position="22"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="449"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="521"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="588"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="638"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="713"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1735764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="735" mass="82552" checksum="16A184B1CB141ADC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7K0</accession>
    <name>A0AAD9D7K0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_013485</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7K0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF171">
        <property type="entry name" value="NUCLEAR VALOSIN-CONTAINING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042031604" evidence="4">
        <location>
            <begin position="23"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="554"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="238"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1735779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="792" mass="87348" checksum="75EBE7A1FA311A0A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7Z9</accession>
    <name>A0AAD9D7Z9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_011683</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7Z9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="8"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1737397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="95" mass="10673" checksum="3F60BCC935074506" modified="2024-05-29" version="1" fragment="single">ETEADSCCASCGIAEVDDIKLKICTACKSVRYCSVECQQEHRPQHETNCKERAAELRDEILFRQPESSYLGDCPICCLPLPLDIQRAMLQTCCSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D826</accession>
    <name>A0AAD9D826_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2OG-Fe(II) oxygenase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011773</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D826"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isopenicillin N synthase-like Fe(2+) 2OG dioxygenase" evidence="2">
        <location>
            <begin position="361"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="522"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="579"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="740"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="524"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="745"/>
            <end position="766"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="943" mass="104288" checksum="3B2267B6CE5FC9F0" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D847</accession>
    <name>A0AAD9D847_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sialate O-acetylesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_011558</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D847"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005181">
        <property type="entry name" value="SASA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03629">
        <property type="entry name" value="SASA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sialate O-acetylesterase" evidence="3">
        <location>
            <begin position="16"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="189"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1737786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="225" mass="25657" checksum="3A8431CACDDBA125" modified="2024-05-29" version="1">MELGSSMNYTTRDFELHKVARGGSGLYEHWYPNHGMHWNLLRSAIEEQRGQQGDWKGFIWHQGSQAVWSAQQYGEDRSLTYYGNLTGFVSEVRELMFQNSITWRCKEEIPVVIVQVGFWPGYKDAANRTRDAQAKFCNQDPRAVLVKTDDLSRYYHYDAASFLISGNRIAQAYQEALGGVVECPDERVPSSSPSEKSMEPSMSLEPTVMRLETDLPSSINTNELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D857</accession>
    <name>A0AAD9D857_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatidylinositol-4-phosphate 5-kinase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011588</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D857"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.110.10:FF:000002">
        <property type="entry name" value="Phosphatidylinositol 4-phosphate 5-kinase 8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23084:SF263">
        <property type="entry name" value="MORN REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23084">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="284" mass="31190" checksum="65709BEF301B506B" modified="2024-05-29" version="1">MAARGDSDTIIGYNYIYKNYADGSVYEGNWKDGKRHGEGKYTCAFGSVYEGDWKDGKMHGEGKLTTANGEVYEGEFKNGKFHGEGKYTFASGNMYEGNWRDGKKHGEGKNTYADGEVYEGEFKNGKFHGEGKYTFADGDVYEGNWKDDTKHGEGKDTYADGEVYDGYWRDDKMHGEGKYTYANGDVYDGYWRDDKKHGWGEMTSASGSVYEGNWKDGKRHGEGKCTFADGSVYEGNWKDDKPNGKSFAELLVSEVFYSAGKAAGEAAGKAAASAGFAALGLGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D904</accession>
    <name>A0AAD9D904_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribulose-phosphate 3-epimerase</fullName>
            <ecNumber evidence="3">5.1.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.1" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D904"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004750">
        <property type="term" value="F:D-ribulose-phosphate 3-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00429">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000056">
        <property type="entry name" value="Ribul_P_3_epim-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11749">
        <property type="entry name" value="RIBULOSE-5-PHOSPHATE-3-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00834">
        <property type="entry name" value="Ribul_P_3_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01085">
        <property type="entry name" value="RIBUL_P_3_EPIMER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="142" mass="15450" checksum="85F14A3F1A0A86E7" modified="2024-05-29" version="1">MVWGNNEYIIAPSILSADFARLGEEVDNVIKAGADVIHFDVMDNHYVPNLTIGPMVCKALRDHGVTAPIDVHLMVSPVDALIEEFIKAGASHITFHPEATNHIDRSLQLIKNGGCKAGLVFNPATPLDCCKYVLDKLDIISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9N8</accession>
    <name>A0AAD9D9N8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011157</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9N8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="294" mass="34131" checksum="B203279C3E725235" modified="2024-05-29" version="1">MADGGDDVFVYMGGEQEVPRDVKHVIIDRSLSSSEKYKIARRQGKKIEREAFYDCRELTDVEFGIELERIRDCAFRYCESLQNISMPSVRTIEAVAFEDCTALSDAEFGCNLERIQQYTFYNCPNLRRIAIPLKDDIFPLNPIQHRCTQFEHCPNLTTVDLVGGIHKAVSSLLLESWRTEIIAEINRINQDLPSTDYLGKADAIQTWIRTVIDRMEHYKAEHYRLLKEDMTQLELAVWKAKLDEKEDGYSNQKVQAKKSKIDVESARKERRIKSGADIIIRNVLPFLQLFEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9W5</accession>
    <name>A0AAD9D9W5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_010938</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9W5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050889">
        <property type="entry name" value="Dendritic_Spine_Reg/Scaffold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24166:SF48">
        <property type="entry name" value="PROTEIN VAPYRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24166">
        <property type="entry name" value="ROLLING PEBBLES, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="76"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1738269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="421" mass="44743" checksum="9BE35B75FBAB671C" modified="2024-05-29" version="1">MTSATAAAANQTSSNSRFRCPCQHIPLSLSSATSAEYGDVTSLARRMKAANQNNILSSKNRQAGGGLSAIPGISDGGITPLHLAAQHGHPAAVSLLLSEGWCDGDTGLPIVMTGGGGGNDNHNDCDRNNSVDSNHTANVTKLCGATPLHRASFSGAISAMQVLLSWRQRDTDNRGGVGDPNGGVNVLSRDVSFGDQRTPLHKAVAGGRPLAVQLLLNALRERELLRDGLLARDAVGLTPLELAKQFILLDEVELEQERCSVRRWDVVAGGSSADWDTCQRLLEGCMSDANVSINNPNTTTQTNRTMPEMPPCTNDDDCVDGKCRTAAWENAFRIALISSMKTSLDNNANETIGGNKNGHVTPTKSMSNGFEGTQTPNIKTVTSNAVKKTSIGRKCDACGNPSTVLFRAKNRQLVCKPCHRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAE5</accession>
    <name>A0AAD9DAE5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010155</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAE5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="174" mass="18914" checksum="53CF4A255BDD13C0" modified="2024-05-29" version="1">MADEENPKMDEVPVGGLVVGDGEQATEEKPASTEGKAAEGSTTVAGVTMDGTQFPLALILISSIILLIATTSSPGMPSMKYSYEKYAVSVSSISLILSFIALLMHKFAGSLYDKMEKHLCMTMFLWSFIGACFLTFRAPFTTTSNGYFAAWATVYGVPWQWVWILRRSRPTSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAP5</accession>
    <name>A0AAD9DAP5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein-serine/threonine phosphatase, PP2C family</fullName>
            <ecNumber evidence="3">3.1.3.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008611</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAP5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47992">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="284"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="367"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="620" mass="65846" checksum="64563CB0309A52B9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DB12</accession>
    <name>A0AAD9DB12_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCR4-NOT transcription complex subunit 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_010499</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CNOT11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DB12"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030014">
        <property type="term" value="C:CCR4-NOT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019312">
        <property type="entry name" value="CNOT11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15975">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15975:SF0">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10155">
        <property type="entry name" value="CNOT11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0943">RNA-mediated gene silencing</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="188"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="250"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="270"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="285"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="298"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1739183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="477" mass="51675" checksum="77D54FCF2D0B2724" modified="2024-05-29" version="1">MEDIEDSIISSMLMGGGGPPPPDTAPPLLSEVPLSITALSPLTSDHSEELGITQLFAAAALSSSSSSTAPSLDLSSSVVPPMVVNKEMIRQQAPPIAAAPSPTSTSLLHQYTSNNNNMEPPFMSPRPLPPPLIPCIGYDDPLSIGLTCENIVGERPSFSAATPPTGDILDMLQSELIWLTPQYPTNRLVLMSPDDDDDDDTGGNKKQAMGNSSSLEAEIVDILKNRAFGIPLTPMDERKVLDALSGADMQEEKSTESTVAAAVNSTVSKKQGKKNKKGKSKSKRGQQQQQQTSASSLTKDKAGSSRSEQRALSIIADSGLTPQNLSRLVENNPIIAIDCLLLILTCPEECIPTNDKNEYLSSLAGMDMSIHSMEVVNRLATHSTRANNQVDVEPLLHPEYIHLYISTCISSCEGMRYDRHLQNKSVRLVCVFLQSLIRNGIVTVEDLYVEVQSFCIEFSRIREAAALFQLLKNQVNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DB90</accession>
    <name>A0AAD9DB90_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Non-ribosomal peptide synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008413</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DB90"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042159729" evidence="2">
        <location>
            <begin position="25"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="227" mass="24514" checksum="D6349BB8A4FF625E" modified="2024-05-29" version="1">MTSAMGSTLPWVSILLIACMAVSSSVVAAVAPNGGQLFGQINRIPASSIPPSSSQLQQQFLVFRGGAASDEYDSDEYDSEYDSDEEEEEPIVTKAKKLATSTKTATQKKALKQTAVKTAALKSKVSVAMASSSSSSKPVAKKKGVYKRFVPYIVRACLNPFTLVAMTKAFFVSLMDINYLNKEEPSQNLRSALEEKARKQQPGPTKPKRKMKPGQAKTISDLPQLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DC53</accession>
    <name>A0AAD9DC53_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MAP3K-like serine/threonine kinase</fullName>
            <ecNumber evidence="3">2.7.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008659</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DC53"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050167">
        <property type="entry name" value="Ser_Thr_protein_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257">
        <property type="entry name" value="SERINE-THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257:SF958">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE WNK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="136"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="542" mass="61233" checksum="09AFCCE8A59CCF25" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCR8</accession>
    <name>A0AAD9DCR8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">lipoyl(octanoyl) transferase</fullName>
            <ecNumber evidence="3">2.3.1.181</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_008220</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LipB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.181" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCR8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033819">
        <property type="term" value="F:lipoyl(octanoyl) transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16444">
        <property type="entry name" value="LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00013">
        <property type="entry name" value="LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000544">
        <property type="entry name" value="Octanoyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020605">
        <property type="entry name" value="Octanoyltransferase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00214">
        <property type="entry name" value="lipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10993:SF7">
        <property type="entry name" value="LIPOYLTRANSFERASE 2, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10993">
        <property type="entry name" value="OCTANOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21948">
        <property type="entry name" value="LplA-B_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01313">
        <property type="entry name" value="LIPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="7">
        <location>
            <begin position="198"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="212"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1740968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="500" mass="56959" checksum="27990B6D13FE1568" modified="2024-05-29" version="1">MQPKPTEAGPWGTWQSNSRHLSQSTKQRVAEKIIAKAHLSLIEPMQQLMQHLLLYPKRCSFITTSYSEARRVKQNNFSSICHITTHRSNSTHSTNNITNNSAYVRSALSAGPIPYQKGWAWQQVLLNRRMNYMRMQEKQETSPDGNYSEQDKDWILMFEHQPVYTLGRGATEDYLTFLNNEADGGLEKRTRLSRKYRGEDASRLNIDRFQKHNTSGTADNPTAEQDDVDKLSNQSICKQPVLAPNGSPIYRIERGGEVTYHGPGQLVMYPLLNLKQPNYQQDLHWYLRQIEEVIIQTLLHFDIKSNRDDINTGVWVGKNKIAAVGVSASKWITTHGLALNVSPNLEHFDKDIITPCGIEERGVTSISEVLRGTSSEHCPSLNEVADVALKCFGEVFHVDVTEGRPISIALLVSQEQQYCIKDLLIEFKVRPPDDERGLMRKYHVKSLKAYKQEQMGVPRMTCSQPHACMPQNLTTGGFYLQYNAITITLCRNLPVIIEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DE75</accession>
    <name>A0AAD9DE75_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_004919</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DE75"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1744386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="247" mass="26678" checksum="2DADC98F584DE4D0" modified="2024-05-29" version="1" fragment="single">SLHSLFLRRCQIGCKGVIAIASLLVPHNSEWAPLPIKTLDLSRNEIGIDGVTALAKVISWDGCSLKALDLSRCNITGERSRGLHRLFSVLRSNARNAAMASANLACVSTKLPSTGNASNLLTLKLNGNDLDSNCFNAIAACIAGDSFTDDNNRKVHYCPSLKNLYLDNTNMSSSSAKKLAKALVTNTGLKILSLSENLIGDDAAKALQMGYVPIKHYRCCFWAVQIHYARGCRALATCVYDETCLAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEG8</accession>
    <name>A0AAD9DEG8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_004740</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEG8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15532">
        <property type="entry name" value="PHD2_CHD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059153">
        <property type="entry name" value="NSD_PHD-1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47025">
        <property type="entry name" value="AUTOIMMUNE REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47025:SF2">
        <property type="entry name" value="AUTOIMMUNE REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23011">
        <property type="entry name" value="PHD-1st_NSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="460"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="118"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="228"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="50"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="145"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="239"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1744207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="509" mass="56724" checksum="864900C2F6509373" modified="2024-05-29" version="1">MKQDDDEKMAKSPSLNVSATHKTGGNGYDDTSPEGISTTSSSKPLKRSRSSTYSEPSTSTAAARLVSRPTDTVVRDLEYSSHTQDMYQPSCIVELPDEAAAGDQLLIRWPRRDQYVELPRQGKKSKTETGDDLLTGNNIAKKKASSTNSSVQSVSSSARSFDTQDDAAPHKSNVSGGLLVRITLPTKLSAKRKKKGAPCYIKVLAPWLAAERAASNSLNTRQLRSIGIDGHSSCNSNLRRNRRQTRKKNHGEGNIVQRTMSRVGRQYQVSKAALPTSDTWEKERAMKEQHLETGKETDGAATASLEEKDEQDGSTHGTDSADFHQIWSRSLAENAASQGESIDQYMNSLKPFQKAHGMTTLHQSNYKVSEAEQKFENEKETTNAMIQDHALLEGEPLTQTERVALNEAIDEHDKQWPKIAKAVGTTPCRCLIHYYSRYKWGDERERYLEKKNQWELSGHSDYCEVCDDGGDLILCDGCPSAFHIHCIKLSDIPKGKWYCPECQTTKTER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFQ1</accession>
    <name>A0AAD9DFQ1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005042</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFQ1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="58"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="183"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="128"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="16"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="73"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="198"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="208" mass="23212" checksum="5560C7F004C58C5B" modified="2024-05-29" version="1">MLQAANVAERDAKRAAAAKRNRANGGSRRRKQPAAPPSLQSFLEKAIDDAANTALGMFDDDDDSQFSDEISFATGSSHGTSSGEKYSAADDSVEVAAVTTEKERKKLQQHQPDIATFRLKRNGRPYAVKKLVKQLAKEEQKLLRAQRALVEAEESMWKTKWKLYNLADEYGLLCGNCNGNEVEEEERDDHERTSAVVYDDDSYAYSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG64</accession>
    <name>A0AAD9DG64_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_003951</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 5"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DG64"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050689">
        <property type="entry name" value="FKBP-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516:SF443">
        <property type="entry name" value="FK506-BINDING PROTEIN 59-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042235317" description="peptidylprolyl isomerase" evidence="7">
        <location>
            <begin position="18"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="8">
        <location>
            <begin position="61"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1744660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="287" mass="31102" checksum="05042032520C4FD4" modified="2024-05-29" version="1">MMIRLLTTLITLCLADAFSRPAQGGPRPFTTRLCSTAEQIFPEGISKTVTQQGNGRSVRPGDNVVVKYVCNAVGSDAAFSRSDRQRFVAGDGIMIPGFDVAIRSMKEGERASVRISDPKYGYGEAGVPPFVPPNAQLELDLEVLNIEESVGLSADPAEMGALGMDGPINRPRTPAAIAAAYEQRMKQKAMNEPEEKEGIEWVVDKVKNSYFFGLFEGETGQEAPWYLKPSITFPIAFLVVGAAFWASLAGGAISERGMPTTDELDEIIISSDFIRSTVVMAFSAMEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG80</accession>
    <name>A0AAD9DG80_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF1501 and DUF1800 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003946</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1746022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.530.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014917">
        <property type="entry name" value="DUF1800"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43737">
        <property type="entry name" value="BLL7424 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43737:SF1">
        <property type="entry name" value="DUF1501 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08811">
        <property type="entry name" value="DUF1800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1241"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1503"/>
            <end position="1681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1241"/>
            <end position="1256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1257"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1523"/>
            <end position="1681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2092" mass="225711" checksum="350F1281D1840B83" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGL8</accession>
    <name>A0AAD9DGL8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SprT family zinc-dependent metalloprotease</fullName>
            <ecNumber evidence="2">3.4.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGL8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006640">
        <property type="entry name" value="SprT-like_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23099:SF0">
        <property type="entry name" value="GERM CELL NUCLEAR ACIDIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23099">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10263">
        <property type="entry name" value="SprT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00731">
        <property type="entry name" value="SprT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SprT-like" evidence="1">
        <location>
            <begin position="2"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="154" mass="17502" checksum="DA604E54603A1153" modified="2024-05-29" version="1" fragment="single">SETFAEFNQRAFANQLSSVKVEWSKKLNTTAGITRMRGKLGEQYSDSRVATIELATKVIENEEQLRSTLLHEMCHAAAWLVDGVHKPPHGKVFKNWASKSMRKIKDVEVTTTHDYQISYKFAWACTNAKCNVVIKRHSRSVDLNKHCCGKCKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGS4</accession>
    <name>A0AAD9DGS4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003408</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGS4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="407" mass="41651" checksum="24A0968F1F534FB4" modified="2024-05-29" version="1">MIPLENAILSDVGSNIGSGFSGSISAKPSDEINGAKECSHEDKAECAYVNGVMTFYPDGHFTGGGAYALAGSSGSGSGNSDGAYAIAGSSGSGSGNVDGAAYAIAGSSGSGSGNAGGAYGVAGSSGSGSGSSQSDSYPAASALNAHQVMASDSGSEFDACDGATLIHDSMQGNDYSNVDGVKSVTFKEKTNCPAIVAAKAAVVEEEEDNTAMLVGIPLAAALFVALALLVARRMRDDREEFPLSSGLDDFMGPPEDPYANTIDVHKCTSMYCNCNKALENVSFIPAPREVDLAQARAYAGLPAVTNTTADEGDWFPEEKARDADSDTVTGVHNGSTNGQVPAPDDSRSYLPVEQRPLMTVSEIPHDSEIDTELESLEGGDDATSIPPPPPPPSSLYHDDEPDDEMSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIU1</accession>
    <name>A0AAD9DIU1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dolichol-phosphate mannosyltransferase subunit 1</fullName>
            <ecNumber evidence="4">2.4.1.83</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_000766</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a di-trans,poly-cis-dolichyl phosphate + GDP-alpha-D-mannose = a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + GDP</text>
            <dbReference type="Rhea" id="RHEA:21184"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the dolichol-phosphate mannose (DPM) synthase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.83" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIU1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004582">
        <property type="term" value="F:dolichyl-phosphate beta-D-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06442">
        <property type="entry name" value="DPM1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000122">
        <property type="entry name" value="Dolichol-phosphate mannosyltransferase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039528">
        <property type="entry name" value="DPM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43398">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43398:SF1">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="2 4 7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3 4 7" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042237984" description="Dolichol-phosphate mannosyltransferase subunit 1" evidence="5">
        <location>
            <begin position="28"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="6">
        <location>
            <begin position="57"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU365083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1748827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="281" mass="30706" checksum="D19F81DAD699E91B" modified="2024-05-29" version="1">MNNLRHLFYAVIACAFSLVVLVSSTQATIDNSPASSTSEEGACLTSISTNSSNMLYSIILPTYNERENLPIMTQLIHDTFTDAKLNYEIVVVDDNSPDKTLNVAQSLQSIFGKDHIKIVSRAAKLGLGSAYSAGLKVSSGQRIILMDADLSHHPKFIPEMIAVMDSTTKKVDIVSGTRYSRGGGVAGWDTYRKLTSCGANFLAKFLLATGGASDLTGSFRLYERYALEQILPQVKQKGYAFQMEIIVRAHKSGMKIGDVPITLSIAFMERVNSEQMKLSCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJ89</accession>
    <name>A0AAD9DJ89_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001713</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJ89"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="99" mass="10693" checksum="D7A05E1D37ADE831" modified="2024-05-29" version="1">MNSFQLAARRTQAMASRRFFSKGSIPTSSAAEVDGVKVVGLPHLSTSSMKWADRQKHWLSDPGSYPLIAILAGTGCFVTGFIGYFTASSPDVQISPLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-12-02" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6V0W7S4</accession>
    <name>A0A6V0W7S4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Diadinoxanthin de-epoxidase</fullName>
            <ecNumber evidence="4">1.23.5.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_012936</name>
        <name evidence="3" type="ORF">SMAR0320_LOCUS11634</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.23.5.-" evidence="4"/>
    <dbReference type="EMBL" id="HBGZ01016244">
        <property type="protein sequence ID" value="CAD9604794.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6V0W7S4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046422">
        <property type="term" value="F:violaxanthin de-epoxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010028">
        <property type="term" value="P:xanthophyll cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044682">
        <property type="entry name" value="VDE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010788">
        <property type="entry name" value="VDE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33970:SF1">
        <property type="entry name" value="VIOLAXANTHIN DE-EPOXIDASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33970">
        <property type="entry name" value="VIOLAXANTHIN DE-EPOXIDASE, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07137">
        <property type="entry name" value="VDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042404972" evidence="1">
        <location>
            <begin position="17"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="VDE lipocalin" evidence="2">
        <location>
            <begin position="104"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CAD9604794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1736336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="466" mass="52184" checksum="79E4C838C9E4DF14" modified="2020-12-02" version="1">MKYCLLALVSLGPTLSWSFAPSSTSLVGSRTATSLSAQKWDLFEDRTVSKNVNTDIFERVGKIAASSLLALTLSFSAFTAPFPTGEMVSSVPSAQAADGAAIGLCLLKKCRLPLAKCITNPNCLANVICINTCNGKEDEEGCQVECGNTFENEVVGEFNKCAVSDMSCVPQKQDDGSYPVPSKDVLVQKFDTKLWNGRWYITAGQNKLFDIFDCQVHFFTETEPGKFFGKLNWRIEEPDGEFFTRDAIQEFYQDPKNPAHLINHDNEYLHYQDDWYIVDYAEDDNKEGVPPFAFVYYRGANDAWIGYGGVVVYTRDAKLPESLLPRLREAAKKVNFDFDKDFAFPDNTCKTMEKGEAVVLREKFAGKMAIQTEQQLQQQAVLARTAASNVVTTEVTAAERAIVDFEKEIAKDVISVEKEIVKDVVNIEKEVVKDVVNIEKAIEAEEKEIVNEIVKEEQSLLNMFKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2Q0K8</accession>
    <name>A0A7S2Q0K8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_004022</name>
        <name evidence="8" type="ORF">SMAR0320_LOCUS21993</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 5"/>
    <dbReference type="EMBL" id="HBGZ01030910">
        <property type="protein sequence ID" value="CAD9628805.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S2Q0K8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43811:SF19">
        <property type="entry name" value="39 KDA FK506-BINDING NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43811">
        <property type="entry name" value="FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042409329" description="peptidylprolyl isomerase" evidence="6">
        <location>
            <begin position="20"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="7">
        <location>
            <begin position="86"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CAD9628805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1744731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="185" mass="19071" checksum="90261F5B38E376FB" modified="2021-06-02" version="1">MKSFVAAIALLLCVSSTAAFSVNGGESDRRSFLTKTVASVIPAAAVVIAAPQSSLAGPEIITLPSGIKYAVTKEPTDKKPVAPQKGDIVGIDYTGYLANGQIFDATHAGGKQNALLFKIGTGSVIPGLDEMVSQMVVGQKVQAIIPPSLAYGDKGVCLDDGECLIKPGSTLVYDILLKKSSIPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1LV84</accession>
    <name>A0A8K1LV84_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 13">Cytochrome b559 subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 14">PSII reaction center subunit V</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12 18" type="primary">psbE</name>
        <name evidence="17" type="ORF">QTG54_017189</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="18"/>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2021" name="Front. Plant Sci." volume="0" first="0" last="0">
            <title>Chloroplast Genomes for Five Skeletonema Species: Comparative and Phylogenetic Analysis.</title>
            <authorList>
                <person name="Liu S."/>
                <person name="Xu Q."/>
                <person name="Liu K."/>
                <person name="Zhao Y."/>
                <person name="Chen N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CNS00100</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 14">This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="12">With its partner (PsbF) binds heme. PSII binds additional chlorophylls, carotenoids and specific lipids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterodimer of an alpha subunit and a beta subunit. PSII is composed of 1 copy each of membrane proteins PsbA, PsbB, PsbC, PsbD, PsbE, PsbF, PsbH, PsbI, PsbJ, PsbK, PsbL, PsbM, PsbT, PsbX, PsbY, PsbZ, Psb30/Ycf12, at least 3 peripheral proteins of the oxygen-evolving complex and a large number of cofactors. It forms dimeric complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12 14">Plastid</location>
            <location evidence="12 14">Chloroplast thylakoid membrane</location>
            <topology evidence="12 14">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12 14">Belongs to the PsbE/PsbF family.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MW679506">
        <property type="protein sequence ID" value="UAM91392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_010200902.1">
        <property type="nucleotide sequence ID" value="NC_058701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1LV84"/>
    <dbReference type="SMR" id="A0A8K1LV84"/>
    <dbReference type="GeneID" id="68638030"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009539">
        <property type="term" value="C:photosystem II reaction center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009767">
        <property type="term" value="P:photosynthetic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.860">
        <property type="entry name" value="Photosystem II cytochrome b559, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00642">
        <property type="entry name" value="PSII_PsbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006217">
        <property type="entry name" value="PSII_cyt_b559_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037025">
        <property type="entry name" value="PSII_cyt_b559_asu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006216">
        <property type="entry name" value="PSII_cyt_b559_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013081">
        <property type="entry name" value="PSII_cyt_b559_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013082">
        <property type="entry name" value="PSII_cytb559_asu_lum"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01332">
        <property type="entry name" value="cyt_b559_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33391">
        <property type="entry name" value="CYTOCHROME B559 SUBUNIT BETA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33391:SF9">
        <property type="entry name" value="CYTOCHROME B559 SUBUNIT BETA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00283">
        <property type="entry name" value="Cytochrom_B559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00284">
        <property type="entry name" value="Cytochrom_B559a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000036">
        <property type="entry name" value="PsbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161045">
        <property type="entry name" value="Cytochrome b559 subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00537">
        <property type="entry name" value="CYTOCHROME_B559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 18" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="7 12 14" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4 12 14" id="KW-0349">Heme</keyword>
    <keyword evidence="9 12 14" id="KW-0408">Iron</keyword>
    <keyword evidence="10 12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 12 14" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="11 12 14" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="18" id="KW-0934">Plastid</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="5 12 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 12 14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="Photosystem II cytochrome b559 N-terminal" evidence="15">
        <location>
            <begin position="7"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Photosystem II cytochrome b559 alpha subunit lumenal region" evidence="16">
        <location>
            <begin position="43"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <note>ligand shared with beta subunit</note>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1732146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="UAM91392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="84" mass="9514" checksum="B5FAAB5BD2E30B60" modified="2022-08-03" version="1">MSGGSTGERPFSDIITSVRYWIIHTITIPSLFVSGWLFISTGLAYDVFGTPRPNEYFTQDRQQVPLVNDRFSAKQELEDLTKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRV0</accession>
    <name>A0AAD8XRV0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Elongation factor Ts, mitochondrial</fullName>
            <shortName evidence="4">EF-Ts</shortName>
            <shortName evidence="4">EF-TsMt</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_016833</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the EF-Ts family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000066">
        <property type="protein sequence ID" value="KAK1732439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRV0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.20">
        <property type="entry name" value="Elongation factor Ts, dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00050">
        <property type="entry name" value="EF_Ts"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036402">
        <property type="entry name" value="EF-Ts_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001816">
        <property type="entry name" value="Transl_elong_EFTs/EF1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014039">
        <property type="entry name" value="Transl_elong_EFTs/EF1B_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11741">
        <property type="entry name" value="ELONGATION FACTOR TS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11741:SF0">
        <property type="entry name" value="ELONGATION FACTOR TS, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00889">
        <property type="entry name" value="EF_TS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54713">
        <property type="entry name" value="Elongation factor Ts (EF-Ts), dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 6" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Translation elongation factor EFTs/EF1B dimerisation" evidence="5">
        <location>
            <begin position="42"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1732439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="144" mass="15977" checksum="38D49E926C737DED" modified="2024-05-29" version="1">MMDCKKVLNQFDGDVEAAAEELRKKGLATADKKASRVAAEGKIATAKRDSTTTGAYIHMNRIGVLVEIEGGTSELCTDVAMHVAAMNPLYATRDDVPAEDIEKERAFLTEQVAEVESQRKLSRRWLRDVLTSSLLRTVLLTRHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XS16</accession>
    <name>A0AAD8XS16_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Inward rectifier potassium channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">QTG54_016961</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000072">
        <property type="protein sequence ID" value="KAK1732331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XS16"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034702">
        <property type="term" value="C:monoatomic ion channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005242">
        <property type="term" value="F:inward rectifier potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034765">
        <property type="term" value="P:regulation of monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1400">
        <property type="entry name" value="G protein-activated inward rectifier potassium channel 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041647">
        <property type="entry name" value="IRK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016449">
        <property type="entry name" value="K_chnl_inward-rec_Kir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013518">
        <property type="entry name" value="K_chnl_inward-rec_Kir_cyto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040445">
        <property type="entry name" value="Kir_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11767">
        <property type="entry name" value="INWARD RECTIFIER POTASSIUM CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11767:SF103">
        <property type="entry name" value="POTASSIUM CHANNEL INWARDLY RECTIFYING TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01007">
        <property type="entry name" value="IRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17655">
        <property type="entry name" value="IRK_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11 16" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 11" id="KW-0630">Potassium</keyword>
    <keyword evidence="3 11" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 11" id="KW-0813">Transport</keyword>
    <keyword evidence="5 11" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel inwardly rectifying transmembrane" evidence="14">
        <location>
            <begin position="239"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="Inward rectifier potassium channel C-terminal" evidence="15">
        <location>
            <begin position="321"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="Inward rectifier potassium channel C-terminal" evidence="15">
        <location>
            <begin position="516"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="24"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="454"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="478"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF17655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1732331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="637" mass="69875" checksum="3994AC6F6600CF50" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XS33</accession>
    <name>A0AAD8XS33_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Selenoprotein family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016862</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000066">
        <property type="protein sequence ID" value="KAK1732468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XS33"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039992">
        <property type="entry name" value="Sep15_SelM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13077">
        <property type="entry name" value="SELENOPROTEIN F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13077:SF6">
        <property type="entry name" value="SELENOPROTEIN F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042053647" evidence="1">
        <location>
            <begin position="27"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="211" mass="23993" checksum="B6D29AA304B31DE9" modified="2024-05-29" version="1">MSKMMMLSLTLLMVAVALLQSTPVTAQKVSENWCLERGFDPTNLSCDTCRLIDESTTIQKLQQEQNINIGEECRQCCQFHKVNPVLHPDYSLRGKYKFALLTYNEGSLSQFGEIKDFLERDLNDVLSFKGESRFKAVASTKSSMDAEMRMQMMMMGITNGGGGQPKLMLFDKHKKGGWSEEDEEEAVEVIKLRGWKREDLKDMLMTLLPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XS65</accession>
    <name>A0AAD8XS65_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016783</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000065">
        <property type="protein sequence ID" value="KAK1732500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XS65"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052201">
        <property type="entry name" value="LRR-containing_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24111:SF0">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24111">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="624"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="678"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="44"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="95"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="681"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="710"/>
            <end position="719"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="734" mass="81716" checksum="278EBE6017D45999" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XT35</accession>
    <name>A0AAD8XT35_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">N-alpha-acetyltransferase 30</fullName>
            <ecNumber evidence="5">2.3.1.256</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_016448</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyltransferase family. MAK3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.256" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XT35"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031417">
        <property type="term" value="C:NatC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120518">
        <property type="term" value="F:protein N-terminal-methionine acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044542">
        <property type="entry name" value="NAA30-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45896">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45896:SF1">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="19"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1732910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="180" mass="20139" checksum="F144AD60931EE4E6" modified="2024-05-29" version="1">MVTIDEVNDVNIPDIEGIDFVDYVNEEQLEDVMHLVQKDLSEPYSVYTYRYFLHRWPQLCILAVPSDSADKRPIGCVVCKIDVKRDDDIDAASENTDAARKVNYTGYIGMLAVETNYRRAGIGTALALRAIQRMQQMGLETEVTNKGRCGYMKIALGLLEKSCLSSITSIGTMHIDYGCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XT67</accession>
    <name>A0AAD8XT67_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Phytochrome-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_016356</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000055">
        <property type="protein sequence ID" value="KAK1733025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XT67"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009584">
        <property type="term" value="P:detection of visible light"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050956">
        <property type="entry name" value="2C_system_His_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013654">
        <property type="entry name" value="PAS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016132">
        <property type="entry name" value="Phyto_chromo_attachment"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013515">
        <property type="entry name" value="Phytochrome_cen-reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043150">
        <property type="entry name" value="Phytochrome_PHY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43719:SF28">
        <property type="entry name" value="PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43719">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08446">
        <property type="entry name" value="PAS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00360">
        <property type="entry name" value="PHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50046">
        <property type="entry name" value="PHYTOCHROME_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0157">Chromophore</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="1" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phytochrome chromophore attachment site" evidence="10">
        <location>
            <begin position="240"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="11">
        <location>
            <begin position="648"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="12">
        <location>
            <begin position="947"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="105"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="181"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="8">
        <location>
            <position position="1000"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1733025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1089" mass="121517" checksum="71565A063C32A042" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTB1</accession>
    <name>A0AAD8XTB1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heat shock factor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_016270</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000054">
        <property type="protein sequence ID" value="KAK1733132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTB1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000479">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF206">
        <property type="entry name" value="HSF-TYPE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="6">
        <location>
            <begin position="42"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="246"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1733132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="326" mass="37096" checksum="2CC3960758C9F46F" modified="2024-05-29" version="1">MLIPATTHININKVLKEMNVNQPTPTSNINLSASSSSTPRRTKSEFPIKVYAMLELADNIFEFAQAVTWLPHGRAFKIHDKVKFMNHVVPVFFNQTKIRSFNRQLYMWGFRRIGRGDEQVWFHDNFLRGKPEDMKHMVRTKIKGNTAVSNEDVSVPNFDDLPPLPVCDRRPTAILDEMEHAILTTMPIASGDIARCGSTMRTVSPPQPGNFTGDNNTDHQMIHFNVDCNQDESFQFSGESHHSPLQADTNTMDSTQPMHQARTSVEEPSHSTYSHMNMLREDVNDFCFSPLKQNKEDFEPLPVIDDNAPCDDFASFIEGAIQLIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUH4</accession>
    <name>A0AAD8XUH4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Zf-MYND and TPR domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_015711</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000046">
        <property type="protein sequence ID" value="KAK1733668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUH4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="6"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1733668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="292" mass="32463" checksum="E15CC1EA0BCDEA85" modified="2024-05-29" version="1">MMMCCCASCGVAEADDVKLKNCTACYLVKYCSIKCQKDHRPKHKRACKKRAAELHDEILFKQPESSHLGDCPICCIPLPLDLKESSMKGCCSKVICNGCNYANQTREVEGRLKHSCPFCRQLAPNSQIESDTLELADRVKVNDPVALRQVGSRCHMKGDYNGAFEYTSKAVEFGDVAAHYYLSIMYGDGQGVKKDEKKEIYHLEQAAIGGHTNARNGLGCIEGYRGQHDRAIKHFTIAAKQGHDESVGNLKKLYKVGKVSKEDFAATLRAYQAAVDATKSSQRDAAQEYYQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUL3</accession>
    <name>A0AAD8XUL3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015489</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000044">
        <property type="protein sequence ID" value="KAK1733792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUL3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="298" mass="32854" checksum="6F0FB5B4643C545A" modified="2024-05-29" version="1">MRIKHLPVGNIPLLLSACDESTNTTEYDGGDVPIFAFVDEDGQRFYKCRHVMQEADTKKGRKIAICNSIFHDSNSSNIGSIISHCKSRHWNVKKKKIAAHQKSSLFSFGGFSNKKQKTETAPPIAAPTDEQVNANVAKLDHQSDTTVAASLDDVRATESVLSEGENVATSDTTSDDRHNMSNSVDKADLAEKSGDVVEEIVMESCKGIKFTDVNNVEFNSEYEFVLMYPFNIHATSVQQSYSESNFLPTVTWSADTSGYLISNKCIPLYSRNLSKPNNANTTRSGGTACVECVRLQFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV29</accession>
    <name>A0AAD8XV29_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_014916</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV29"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000039">
        <property type="entry name" value="40S ribosomal protein S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000530">
        <property type="entry name" value="Ribosomal_eS12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047860">
        <property type="entry name" value="Ribosomal_eS12_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11843">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00972">
        <property type="entry name" value="RIBSOMALS12E"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01189">
        <property type="entry name" value="RIBOSOMAL_S12E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="5">
        <location>
            <begin position="24"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1734409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="144" mass="15815" checksum="72D3465E42427609" modified="2024-05-29" version="1">MSDEEIVDAVEEVEEEVAEMNVLDALKEVLKKALVHDGLRKGLHECAKALDRRSARLCCLAKDCENEEYKKLIRALCAEGEVSVIMVDSGKDLGAWCGLAKLDADGEVKKAVRTSCAVITDFGEETRALSVLLDYLQKQADGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVC2</accession>
    <name>A0AAD8XVC2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Acyl-CoA dehydrogenase C-terminal bacterial-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014789</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000038">
        <property type="protein sequence ID" value="KAK1734541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVC2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015396">
        <property type="entry name" value="FadE_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09317">
        <property type="entry name" value="ACDH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase C-terminal bacterial-type" evidence="1">
        <location>
            <begin position="64"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="378" mass="41524" checksum="6C492E7CBAB8D275" modified="2024-05-29" version="1">MKQNCTERGRRIVECGMDIAAGSAICRGDKNYMGNAYMSLPIAITVEGANIMTRSFQIIGQGLTRCHPHMSDLLKALQLPPSEEKHGVKIFVKQFHKIVGHGITNFFGSVSRGVGATFSSATRSKTAYKNGDELLAYHEKQLLRLAANFALTADLCFTLGGRLKFEELLMGRLADALGAIYLGYATLHHYDRRRGIEGLEALTEHAMLRLEREAQEALYAASENFPGPLGPVASTVMKMGCFPLGGLTRPYSDPSDTLTKEVSRLLTTPSEIRDMFQEGIYSAPDGAVHQMTDLINALPICVEADKVATSLRREKREPTAEETNLIAKADALRDALIQVDVFEHATAEEAQPGYVRPALQGTEERFANLDKTVFREAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWW2</accession>
    <name>A0AAD8XWW2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWW2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="349" mass="38523" checksum="870D9A3E6F730673" modified="2024-05-29" version="1">MVQHSTSSSSFVQDAASVAASRFHEAVSHIQKPETRSQIQAKVDYVVKKMFAPCVGDIGGVPLDDTGGGEGSWKCPDAIPMEVSPNTSEENMTAPAAAAAADKQQPQQFTFGKAFPERENNEKRQENSLQKLKKLGARHQLASGYIDPTLPDAARPVSPEEKCAAPSSTDNVDEPVDDEVDFDDGISAISSHTLEEMEKRRQLHTVRVSPTEFSKPKLPPSSKNNTDFSKKPMMETISGGAGGDDDDDDFFGEPFFNQTPPKLERVGVSNVSNDSQQLEKAWNVDEVNYWKGEVNKDKHDDKRSSRREQRSSVEERAKRLRELSRSRSRSGGTHPHDTSGLIDKIRVQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXI5</accession>
    <name>A0AAD8XXI5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXI5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="111" mass="12471" checksum="C31CD0B854A845C3" modified="2024-05-29" version="1">MKRTPAKNQGEESSPSPQRKGASREDRRESSLEEDRPSKKAAKKRRRYECSADGCTNVAQKGGVCMRMGPRESYAALRDVQIMSSVEEYVGGTGRRAIQTINQLRLDHNSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZK7</accession>
    <name>A0AAD8XZK7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012644</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZK7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042219420" evidence="1">
        <location>
            <begin position="21"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="515" mass="56629" checksum="46F1945AFFB71B89" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZX1</accession>
    <name>A0AAD8XZX1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZX1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="204" mass="22967" checksum="4F04E8106284986A" modified="2024-05-29" version="1">MSGKLMTEQQAYEQEESAAAGDEEKETPITSLSCSIPQDGMPFRRSSAPPVTECNVSQAAGRQTQCAPQHEDDCSPSQSADVPTSTSEHIKTRYTAPPKEAHTSTDLNRKDLMVFIQILLKYLDNNDRKLRVEVKKAVADCTKKNREGHPEYRLLVDSITNRLRLVVGDMHWSQLENLMEHYRKKYARAGTTRSSDSVHKFVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0J9</accession>
    <name>A0AAD8Y0J9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Elongator complex protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0J9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="415"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="473" mass="51271" checksum="618A574455752084" modified="2024-05-29" version="1">MTKPASSQSSLNPWEALLASATRARPPQDSSTSTSSSPLTTSDAILGGGYTILLQHSMTPKSQRKWALESTIANVDNNSNSNTTTNASLSSQFASSLSIQQHHHSSNQTSSSSASARRAGGDWYGISGPFLVRQAFHDLSKKCNGRVVLVSVAGTSGICDLDQEYNDADVYDHQSRTDDDKNNVDAVNLFRRNGACVDFNSNPFGWNEDNNNHNSCNDDDSFSTKATLNNLQSIAVAIRQAASRIEENNSEQQSQQPIPIIFDSLTPLLHLHGAERITILLKSLGRTSPPLDNSSNSTNPSLCLSPIIAPILYESICLSDHRTLEDCADAMVQLNLMDSTSTPTNYAIEAKDDNSVVVVSGVMDLIRRGGGGSNGLGGKLMRHCVPVHILRSLSTIGDLRDGCYWIIDNGDDDNTVRDGDATEKKGKKQTSASSTTDEMGQSQSTDNLSRPKIYLEDDDPDFQDYDEDDDLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0M4</accession>
    <name>A0AAD8Y0M4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012793</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0M4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="77"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="206"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="332" mass="38362" checksum="10F60AA748AE8667" modified="2024-05-29" version="1">MKLQEVEKDLAELQVQYQLESDRATEAWSMENERANLLQQTLDAEVETNQFLRSAQEEMKQVIGIEQEHRDLLEAKKQEIEHSLQDTCQNLERANQENSELREQVAEVPRLQDALSETIKSLRESKQEFEKLSEEFDNCQEMKSMLEGKVSALESQVGDQMLDLQAARMSEADVEASLEECMKKVEDQMLDLQAARMSEADVEASLEECMKKVDELVGKLQEMQEVNETEHTRHVEALEQANAENEKLQQLNSSLGKERDELVASVKKLQEECNKERNQVASALEGFDEEMASAEIKLRSTQKELEEEKEKVKLLEVPLEEATRRWRMKSHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0N0</accession>
    <name>A0AAD8Y0N0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SGNH/GDSL hydrolase family protein</fullName>
            <ecNumber evidence="2">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012428</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0N0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00229">
        <property type="entry name" value="SGNH_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051532">
        <property type="entry name" value="Ester_Hydrolysis_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383:SF29">
        <property type="entry name" value="SGNH HYDROLASE-TYPE ESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383">
        <property type="entry name" value="THIOESTERASE 1/PROTEASE 1/LYSOPHOSPHOLIPASE L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="1">
        <location>
            <begin position="50"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="259" mass="28297" checksum="F37DED0E3CFC61E9" modified="2024-05-29" version="1">MLMMVRPIFSILLSLRHNHLHHQRTHSILKSMSNDVISSEGTLPPKRIFCYGDSLTAGTAPPIYDLFPYGQSLESELGNGVVVRWRGLPGWTAQTMVEYLDDGNVGLRAAVNGIDNPPISLVIILAGTNDIGFLTSSMTPTGGATDIDDAVKPIVNLHKACLDITKGEHKIRTLAVGIPGSAWQQMNSSASKLAADMNSSIQQFAQSYPDGLVSYTDFPFLYEKNDLWCSDGLHLSPEGYKRLGNDLAPVVKQILERCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0Q8</accession>
    <name>A0AAD8Y0Q8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Acyltransferase</fullName>
            <ecNumber evidence="11">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_012342</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the diacylglycerol acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="11"/>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0Q8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004144">
        <property type="term" value="F:diacylglycerol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07987">
        <property type="entry name" value="LPLAT_MGAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007130">
        <property type="entry name" value="DAGAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317">
        <property type="entry name" value="DIACYLGLYCEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317:SF63">
        <property type="entry name" value="DIACYLGLYCEROL O-ACYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03982">
        <property type="entry name" value="DAGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1736897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="319" mass="35873" checksum="791B8192AF57951C" modified="2024-05-29" version="1">MCQQTTHQKEKPPIHQWFLGMIVASIFSFAYLIIPIYLLSSACCLILRYPTTNASLAVALPMFISIIIPPLPSTFILRLLKPMLYYFDYEAIYTDDKNVRQAIAGGKNFLFAAQPHGILSFVGMCAAVSKPDDAMKVPTAAASAVLQTPLLKNLMGIFNLVDASAHNLKKILKGGGSVLIYIGGIAELFKSCRAEERLYLKKRKGFIKLALREGVDVVPIYLFGNTSVLSALKHGPLATLSRKLQVSLTWFWGKYYLPIPRDEKILYVVGKPLGLPHIEEPTQEDIDKWHAVYCDEVTKLFELHKERVPTYKHKKLFID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0T2</accession>
    <name>A0AAD8Y0T2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RanBP2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_012230</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0T2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RanBP2-type" evidence="6">
        <location>
            <begin position="213"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="282"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="433"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="500"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="606"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="958"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="52"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="74"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="106"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="175"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="288"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="450"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="621"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="677"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="703"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="750"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="772"/>
            <end position="790"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1737363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="988" mass="105885" checksum="11D82601EBB268C4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1C8</accession>
    <name>A0AAD8Y1C8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012475</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1737030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1C8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050188">
        <property type="entry name" value="RluA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600">
        <property type="entry name" value="MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600:SF40">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE RPUSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="2">
        <location>
            <begin position="126"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="423" mass="45945" checksum="D71A5C3D2898C838" modified="2024-05-29" version="1">MAHKRTIFSISSTYRRRWLLSASLTSFMIMFCAARVCALQHTSLTPLFNPSRAKQCRHSSIRSVTTTLYGFSRQGGNRSKGQTQRPQRRSPQAQQPHPTQQVRRNSSKTSSNNKLEKPEIIFSNNHVLVVNKPAGWKSQPGDGGGQNNDNQSSSYVDPKCLLTYLQSQELGGGSQKNFLSPTHRLDQPCTGVLIFAKNGKAASRIQVAWAKRKVKKIYWVVVEGGDDGLDFLISRSKLVNGSGKNPTYQLSGMLKSTGGGKGGGGPRGNKGGGRGSVICKPLPPNQTSVNGDKSNGGFRVCHIVWEHLKTLTTSKQSTTAPRYLLSVSTDTGAKHQVRALLALAGGAPIAGDLRYGDNYSNRGGKVDAPLPDGSVALHARSVFLPTVSLGGMEFLLDKPFVGNLPGRWREFFGVREQDVKGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1H3</accession>
    <name>A0AAD8Y1H3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011734</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1H3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="188" mass="20528" checksum="4CBC5C8B8EFA7BDE" modified="2024-05-29" version="1">MSDARNSSGNIRGGGSRVTGGSGRTQKHADTGGRKGGGIPGTGSEVLDKKELARRNLQMLSMSKQLALMARESCFTDHTEAEYEELNVPMPDAETAMKKLKAMVKATDDWYDAGFRERFLYDVFEVWKKELKAEFEAAAAKAAASKTAAKQKRSGMGGEGMKEEPIRWKGGDVHRRARGNASGYKYNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2K1</accession>
    <name>A0AAD8Y2K1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nitrate/nitrite transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_011154</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2K1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044772">
        <property type="entry name" value="NO3_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23515">
        <property type="entry name" value="HIGH-AFFINITY NITRATE TRANSPORTER 2.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="384"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="414"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1737860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="444" mass="47744" checksum="E06DFA98F3AEE8C2" modified="2024-05-29" version="1">MIMAGIALSDPNCPFNLLIAAALLSGVGGGAFASSMSNISFYYPKRLQGMALGYNGGIGNLGVSISQLLAPLLMSVGGTSIMIEGDSPVSGWPANAGWLWFPLCAASAILAFFFMSNQPNHGEKTNLVSLINFYWMEAFGFLASFIGVITLIQTRDAAMLNTPAGQVIHKFLLVLLACACEHVFMLLSPKKARDRVKKQVVIFKRKHTYVMTWLYIMCFGSFIGYSGSFPKLIVDLFGYLTADGCLQTAGDFVPAGNGMTSDTCEGEWKVGYDYPNPNAPNGSAVAWIGAAVGSLIRPVGGIMADKYGGAKMTNLAIIWCTLAAFGQGALVQTVSQMEDPTSNKAYYGLFIFLFINLFACCGFMNGTTFRTIGVLFPPEEAGPVLGWSSAIASYGAFVIPVMFGIALQAGNPQITFYCLGGYYVTCFFVNFWYYIRPGCEKPGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3C1</accession>
    <name>A0AAD8Y3C1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_010222</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3C1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="7"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1738906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="449" mass="50454" checksum="B0E617C2A4DC641D" modified="2024-05-29" version="1">MSEVCGNNNCNNLCGDPPRVCSKCKATPYCSRECQKKAWKLHKKLCASLNKGAAQQLHHDDHDEELISEQMHSMVLSSLYMFPRAAQEMYRLFKSTPKEEDDNYLECRVLKMKKLALTLDQCTKEEFMHSLVVLLHPTKTWLIEKPTSPILILFQTGVNADALSTDKRTHLPDDSSYTCLCQIAQLSSAKSDMYNKNQVILGRQFLEVGGANVNARANAGMSFNFPLYNACASRLPTNPEFIQLLLEHGADPNMQTSVGETPLMNCLNYSVGVGIQLLSFEQYHVPINVNLRRYDGHNVLSLVNGSISQISGGTFKDGQETTPMKMEYLLKQLLEFKTLLEARGAMEYEAGDIQAKGGVDMIQQKDIKSSFLLEYDVSSLFNIDLNRGFDAPSWCSGERGFYIRDELAAQYEAHENKEYLHATVGGMWAKTTGGPASRNLRRIGKRFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3D2</accession>
    <name>A0AAD8Y3D2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DNA cross-link repair protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_011024</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3D2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035312">
        <property type="term" value="F:5'-3' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16273">
        <property type="entry name" value="SNM1A-1C-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12650:FF:000001">
        <property type="entry name" value="DNA cross-link repair 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011084">
        <property type="entry name" value="DRMBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240">
        <property type="entry name" value="DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240:SF35">
        <property type="entry name" value="DNA REPAIR METALLO-BETA-LACTAMASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07522">
        <property type="entry name" value="DRMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="7">
        <location>
            <begin position="445"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="DNA repair metallo-beta-lactamase" evidence="8">
        <location>
            <begin position="648"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="174"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="372"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="382"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="408"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1738355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="788" mass="87544" checksum="5A0496AFB6F4C3AC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y439</accession>
    <name>A0AAD8Y439_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dolichol-phosphate mannosyltransferase subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_010974</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the dolichol-phosphate mannose (DPM) synthase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DPM3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y439"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033185">
        <property type="term" value="C:dolichol-phosphate-mannose synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013174">
        <property type="entry name" value="DPM3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16433">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16433:SF0">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08285">
        <property type="entry name" value="DPM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1738305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="112" mass="12463" checksum="0A9B9A95B5109CBD" modified="2024-05-29" version="1">MGLLRRIDPQMTGLLRYQLFLSIGILFIGLWKASITRLATIQKTLSTSIDPSTTKILVIYLPIWAIILLGIYALSSVLYKVATFGDCPEAAVELSGQIEEAKQKLTKQGFKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4D4</accession>
    <name>A0AAD8Y4D4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl hydrolase (Family 43)</fullName>
            <ecNumber evidence="2">3.2.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22925">
        <property type="entry name" value="GLYCOSYL HYDROLASE 43 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22925:SF3">
        <property type="entry name" value="GLYCOSYL HYDROLASE FAMILY PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1055"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1741"/>
            <end position="1768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1744"/>
            <end position="1754"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1861" mass="205624" checksum="F2DA91CFB155094E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4U8</accession>
    <name>A0AAD8Y4U8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SGNH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009746</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4U8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1739203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="108" mass="12359" checksum="4A4B378E66E6C8F7" modified="2024-05-29" version="1">MPLMRSKSEHRPKIVYVITPTAHFNTPDGQYIRKDRMDDERSKCVERVSYNPRAELEKRILKAGVNVDVLLDYDDLELGALHVQRGDCLHYCMPGAADLVAARLLDSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4W1</accession>
    <name>A0AAD8Y4W1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Prolyl 4-hydroxylase alpha subunit-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_010172</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endomembrane system</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4W1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.620:FF:000031">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003582">
        <property type="entry name" value="ShKT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF235">
        <property type="entry name" value="PROCOLLAGEN-PROLINE 4-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01549">
        <property type="entry name" value="ShK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00254">
        <property type="entry name" value="ShKT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51670">
        <property type="entry name" value="SHKT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="ShKT" evidence="12">
        <location>
            <begin position="530"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="11">
        <location>
            <begin position="734"/>
            <end position="839"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1738856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="849" mass="96099" checksum="5DEEDD2AC0FF867C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y522</accession>
    <name>A0AAD8Y522_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">25S rRNA (uridine-N(3))-methyltransferase BMT5-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009798</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y522"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070042">
        <property type="term" value="F:rRNA (uridine-N3-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019446">
        <property type="entry name" value="BMT5-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10354">
        <property type="entry name" value="BMT5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="25S rRNA (uridine-N(3))-methyltransferase BMT5-like" evidence="2">
        <location>
            <begin position="11"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="318" mass="35524" checksum="80FD807E8701FC32" modified="2024-05-29" version="1">MTMAKQLSYILLGDGDFTYSLDMCRYLAALSYAPSTTSGNDNQPPMISSNMTHHNVTCTGVDTSKEVKSKYKDADFILTNIQSINKRSDSTEQQSTKSRITTKIVHGVNAVEPTPDDDNHTPSLQHFDHVLFHHPHLGIEDAQLHKRFLLHFFHAATTRWMKPNGGLLYLTLVRGQCERWMCISGAERHGLVLLRRSKFCPPPPPPPSLSKEKTYYQLRRHQSGKSFANRRVMQGETTQPQRDGGDGESETLVFGRSCDYPLTSSSLDDNVGILPWENAETSPYVNGKSTEGEETKLSSDHVGSSTSLSADPYPCNYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5J6</accession>
    <name>A0AAD8Y5J6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5J6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041928466" evidence="1">
        <location>
            <begin position="31"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="76" mass="8084" checksum="F582F70029D2655F" modified="2024-05-29" version="1">MSKVVHSPAITMKILATILAYSAALVSVNAISNAAHETPESNLISENADEYGADVEGYDGLSIFFKRRCSSPANPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6L4</accession>
    <name>A0AAD8Y6L4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">Aminomethyltransferase</fullName>
            <ecNumber evidence="2 8">2.1.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 8">Glycine cleavage system T protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_008557</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">The glycine cleavage system catalyzes the degradation of glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysyl-[protein] + (6S)-5,6,7,8-tetrahydrofolate = N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16945"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10492"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="2.1.2.10"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the GcvT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.10" evidence="2 8"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6L4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004047">
        <property type="term" value="F:aminomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006546">
        <property type="term" value="P:glycine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.110:FF:000002">
        <property type="entry name" value="Aminomethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1400:FF:000001">
        <property type="entry name" value="Aminomethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.110">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1400">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1250.10">
        <property type="entry name" value="Aminomethyltransferase fragment"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="entry name" value="Probable tRNA modification gtpase trme, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006223">
        <property type="entry name" value="GcvT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028896">
        <property type="entry name" value="GcvT/YgfZ/DmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013977">
        <property type="entry name" value="GcvT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCVT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00528">
        <property type="entry name" value="gcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001567">
        <property type="entry name" value="PRK00389.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757">
        <property type="entry name" value="AMINOMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757:SF2">
        <property type="entry name" value="AMINOMETHYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08669">
        <property type="entry name" value="GCV_T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006487">
        <property type="entry name" value="GcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103025">
        <property type="entry name" value="Folate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="GCVT N-terminal" evidence="9">
        <location>
            <begin position="36"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Aminomethyltransferase C-terminal" evidence="10">
        <location>
            <begin position="327"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR006487-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1740462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="414" mass="45108" checksum="980552A571C89075" modified="2024-05-29" version="1">MMNSTLLVRRTITSSTTRRAFASTTNDDSSLIKTSLYNLHKDLGGDMVPFAGYSLPVLYKNSPNGGVMKEHLWCRSDNKSSLFDVSHMGQIRWHGKDRVEFLERVVVGDIGGLSVGGGCLSLVTNEEGGILDDTVITKYGDYVYMVVNGATKFGDMKHFQQQLDEFDGDVTMEYLEDTMQLLALQGPGAADAVSKILPSGFDLTNMAFMTGTETTLDGIEGCRITRCGYTGEDGFEIAMPAEHAVSIASKLLEDPSVNPTGLGARDSLRLEAGLCLYGHDLNETINPVEGTLAWTMGGPKGRRRAEGGFLGAEKILKPDGKLQKVTKKRVGIMGMKAPAREHAEIYDASGENKIGEVTSGTFSPCLKKPIAMGYVETPLSKVGTEINIKIRGKMQKAEVTKMPFVESRYYRVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9X5</accession>
    <name>A0AAD8Y9X5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA polymerase delta subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9X5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904161">
        <property type="term" value="P:DNA synthesis involved in UV-damage excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019038">
        <property type="entry name" value="POLD3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17598">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17598:SF13">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09507">
        <property type="entry name" value="CDC27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="453"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="256"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="453"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="491" mass="53108" checksum="99F0A249A92CF008" modified="2024-05-29" version="1">MTTASYEAHQLEQILSLLNDQRECLTLRSIMLELTVTRSVARGVLEEVVERAKGTATKYEVVRMIPKRGDDGKRTVMELVATDPSSSGDENKNKGSIFSISICNDAQDETVDMDEDDVDENGNVISNHLTDTSGAAGAIQVVSAAHEKALAVQRDMFTSGSNGGSAQLCSIFGADGVTANGGCYGRCILPAPELCVENEEGIRVIRREKRGRDVVVVGASYPSSTAAGKKSNFGSKTSSSAASKPSTTAKTKKGKATTAAAFFKNASATSSKTKKAEPKKTKKEEEKENSRNKKAITASVDDFVGDVDEDEEFLEEEKARKARVAKEARKEARELMHDEKAKKRNTDGIESRRSNVAPKRQKHDEERKEHDMDIDCDDGDVEDEEKKTGAMDAFTQKKDKSAPAAGGTNSGGVKKRRKKLVEETTVDANGYMRTETITVWEDVSDEEVEFKAKPAVAKAAAPKPKGKSSTVKKSGGSKKQAGLASFFAKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAM0</accession>
    <name>A0AAD8YAM0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phospholipase B-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007672</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAM0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33683">
        <property type="entry name" value="1, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33683:SF46">
        <property type="entry name" value="SUSHI DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042072742" description="Phospholipase B-like" evidence="2">
        <location>
            <begin position="22"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="720"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="735"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="755"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="770"/>
            <end position="788"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="951" mass="104202" checksum="D1F3ABB3CE992524" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YB81</accession>
    <name>A0AAD8YB81_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006847</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YB81"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="193" mass="21489" checksum="73C99E50A2DBFEE8" modified="2024-05-29" version="1">MQDSLREEITSIRYVEPLKFADVKMGSSSQHSHDEQSEGSLTASTTSSYSTSSSTSDADDTNHHDEADGPLSRSVQDPPTSLISRLIIGPDPTLKRRRSVHFHHEVSVVPIPSRTSYTPYTQSRLFIGKKEMISNARRNKREFVYEGFDWRNAVEEDQMYSSLQMDGGELVHPANYVCSSSSPASSSVTKQGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBS9</accession>
    <name>A0AAD8YBS9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_006251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBS9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1742654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="133" mass="15306" checksum="D22B7F0EF00BF346" modified="2024-05-29" version="1">MMAEAHEADDDIFVYMGGDQVVPNDVVRVRIDRSVNMIPTRAFYHRSLLIDVEFHDGIEIIEEVAFFYCCSLISVKLFGVREIKWRAFSNCSDLINVKFVDKLETIEQGAFQDCTSLETIKMPSIRIIDSLHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBY9</accession>
    <name>A0AAD8YBY9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Circumsporozoite protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_006830</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Essential sporozoite protein. In the mosquito vector, required for sporozoite development in the oocyst, migration through the vector hemolymph and entry into the vector salivary glands. In the vertebrate host, required for sporozoite migration through the host dermis and infection of host hepatocytes. Binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes.</text>
    </comment>
    <comment type="function">
        <text evidence="5">In the vertebrate host, binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes and is required for sporozoite invasion of the host hepatocytes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the plasmodium circumsporozoite protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBY9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005046">
        <property type="entry name" value="DUF285"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011889">
        <property type="entry name" value="Liste_lipo_26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051860">
        <property type="entry name" value="Plasmodium_CSP_Invasion"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02167">
        <property type="entry name" value="Liste_lipo_26"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44826">
        <property type="entry name" value="SPORE COAT PROTEIN SP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44826:SF3">
        <property type="entry name" value="SPORE COAT PROTEIN SP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03382">
        <property type="entry name" value="DUF285"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0748">Sporozoite</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041976610" description="Circumsporozoite protein" evidence="8">
        <location>
            <begin position="30"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="392"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="393"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00033726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00045806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1742265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="730" mass="80642" checksum="CFD86D0B7F77242E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCY0</accession>
    <name>A0AAD8YCY0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alkaline phosphatase D family protein</fullName>
            <ecNumber evidence="3">3.1.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004692</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.1" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCY0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="entry name" value="PhoD-like phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33987">
        <property type="entry name" value="CALCINEURIN-LIKE METALLO-PHOSPHOESTERASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33987:SF1">
        <property type="entry name" value="CALCINEURIN-LIKE METALLO-PHOSPHOESTERASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09423">
        <property type="entry name" value="PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="415"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD-like phosphatase metallophosphatase" evidence="2">
        <location>
            <begin position="48"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="448" mass="50551" checksum="DC4CBA48C60EC5F5" modified="2024-05-29" version="1">MQEEASADHELDASFPNINLTRIAFGSCHSRGAVNKRLSTDHNNNKTIWDTIAAVVQPQTFLWTGDAVYPPMEVKGDYPLEVLKYEFYQMKTNTTLGYASFIQNKMLEAGIYGTWDDHDYGGNDRGYELKGKDERRDAYLDFLGVKRKNNDRSGVYNSVEFGKQPNKVKVIFLDTRYARSKHCIPSVGSHPYVPHGAIFACLTRWLTAGFNLCSNGGEVLGEEQWEWFERQLAESKASMHIVVSSIQVLTTNPVVESWGHFPDERERLLKLINPVTGLVLLSGDVHHAEISSTKRINIKSKASSIIEVTSSGLTHSCLGGWYGGFCKPILDYFPKHRFKGGNVASTDDPSYFTKKNFGSISIDWKTRKFHVKVHNESGQVVLHTGPLEIDTAANLSESELAAVDKCIDGHFFITIHLYNMAALVGVVMMFGLVFWMKRRRQRTHTKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD66</accession>
    <name>A0AAD8YD66_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005986</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD66"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041993726" evidence="2">
        <location>
            <begin position="18"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="271"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="303"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="434"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="480"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="550"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="594"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="646" mass="70759" checksum="619F9491F1317C70" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEC1</accession>
    <name>A0AAD8YEC1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MKI67 FHA domain-interacting nucleolar phosphoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_004245</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEC1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12307">
        <property type="entry name" value="RRM_NIFK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46754">
        <property type="entry name" value="MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="66"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="18"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="215"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="249"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="259"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="299"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1744954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="312" mass="35062" checksum="978887F93A5DD7E0" modified="2024-05-29" version="1">MVKSLQRSLEAKLASIEDPVYSDGEDAQNEDSETELISAKINKKSTKRNKRKKDNDKNDTSDEPSSVIYLGHLPVGFEEREITVFLNQFGNVMRCRVSRSKKTGRSRGYAFVEFVDHDVAKVVAETMSGYFLLEKRLVCHILPQDQVHELMFAKAKRIATKADIHKKARLEVNKQRSTDALKGITAKLVKREEMKRKKLASLGIDYDFPGYAAGAGEKPADDAEPSSKRRKTTSSDDNEEEVASDKKAPKSSKKKKKKSNDAKVESEKENVTNTPKKGKDKPTEPLEEAEEAPTTTSRRSTRSKKAKKTPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEC7</accession>
    <name>A0AAD8YEC7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005502</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEC7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014955">
        <property type="entry name" value="DUF1826"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08856">
        <property type="entry name" value="DUF1826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="368" mass="40864" checksum="72D9FB5FB5D86DEA" modified="2024-05-29" version="1">MTIAAATRIIHWCIVLHLSLLQIVGITSFQFRRNNPAFLCISKSIPNAQGRTHDVALSPLLAELSSTVTAADEQQQQQQEQHHRHAIFQHTNAVSKSFPIPHPDIWHKFVTPTSREEESNRNNNSSPSFWEQLLSSAQNKVKNNEKQNQLVNDVTVQFDDATTGAQELVKQCQLFTQRSDDTTDGKQSTLLPENTMMEQEITQHLADVLSYFQAVAGNDNSNIKCQARIVSSIGKNGIKCPRWHADHVPVRLVMSIIGPGCEYIPHEVEIMGSSSNSRLVDRNALNTLDEDDTRIANDIIVPPNLNTEKTGVISAKEGDAVLLMGRAWEDSSEGDFTDDAKLAAVHRSPLLSSGQERILLTVDLVPHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEL4</accession>
    <name>A0AAD8YEL4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005604</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEL4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="443" mass="49725" checksum="7AFA2777BA50B2B6" modified="2024-05-29" version="1" fragment="single">SGLTFWLDVDRDHGTAPHPRAYLLLTAEVRIAVIVENKKTAALTLPYSSKLKSYSQIQTPNMQPRLRKTGNQKPCGKNNNLIISHALTFAAGLIIYSLFNTEDCGDVVMKALKNAKNDNKIQNPPPVAVAKASLRSEPQTVQLYAPAKAKEKEGRKGELNFFDIGITTGTDKVLGEKNLPLCLKDDKACGQPQQVRDECRPFGHFYHTMYQQTIGSYSLDDAAPFQFLEVGFFHGNGYDMYREFLPRGDCHSIEISCLPPGSREEGKWPWGNFPEENPRYKQYLDENRLHCGDGSDPNFLMEVWKNEMKVPGAPPLKIVVDDGSHEAAHMAQTVMFWLPRIEPGGVLVVEDIQPTSVANPFTTQFLPQIMKDLHYCGDKDKPTEDKACFPTLVGMIQSIHCEMHICVFERNQAPAKELSLEESSLPENALDMKKCKSMLPGHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YER1</accession>
    <name>A0AAD8YER1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004133</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YER1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041967114" evidence="2">
        <location>
            <begin position="26"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="240" mass="27367" checksum="1A973E69909B4E16" modified="2024-05-29" version="1">MRRLFGSTAMTVLFVSLRGNSFASAFCVPASSENMFRLRSGALFSSTTSSDTTFWRSNQDCWRPDVRDVERISFGQPAKKKGTGSRGIPHRLNEDERRSFDQARRQGFLQVTGSAWRSQRRDAPLLNTYRSLSDARGKPAIVLHKLSPTSSGEHEDKLVVDLSPLRFPDEFDAVGEEVKAMIQAEYNLESCVDDVEEGGGVMTKDWISWRRATKINMKLDQYINYRHFSWNGMFHGKRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YER4</accession>
    <name>A0AAD8YER4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005679</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YER4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="138" mass="15572" checksum="84442C18B8528C07" modified="2024-05-29" version="1">MLSTMAEAEELIVDFPTHRSRSMKPVHFADTSTLYIVHRHEDDNKGVHRHELWYNKTDYSRMKRANQKSVIKVRAMASAGVPVSYSGDGGSSDDCLIAIEHLLTPATVREALACKQRCVRAVSRPRRTRKASDDESIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YES0</accession>
    <name>A0AAD8YES0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sulfotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YES0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="347" mass="39274" checksum="471FDC7C327EDA5E" modified="2024-05-29" version="1">MNRKNEKKSLGSSSSKILALLSTNRKAIGGTLVLLAIPALLNNLLTPADVSSQESRKSEKSNSQQLNSSISTDSSIFREKAEKLSNSFRQKGGIFVFLHIPKTGGTAVRSYLMDQILNDTSYLGCWKGQKVNDALISDYCEHAGTPNKTIVVYEAHGGPPCLFYNQLSNTLGKWRELAKKNGVPFFAFTLVREPISWYQSFYNFFITKVGQNVTDAGFFDDPHMKANMQCAELFGIHWRTCMDALALFKNQMDWVSTTDKLSMELIPLISYLGRFENRNLSVILPHTQQRKKLVLSEFSEKGKEHLRNWTEWDLLLYNDIQGSYDFNNNWKAFLDANGALHPVQYGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEU3</accession>
    <name>A0AAD8YEU3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004178</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEU3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="180" mass="19487" checksum="E935FBC20AF72B19" modified="2024-05-29" version="1">MSSNREIYGKDGGDKRDSFNEYDWVAAAKGASFSHGDDAHDNSDAHRPNEKSKKGASSSASSAAAGSALSEISCDAVSIMEWATDLLSPSSSENNAQDVFAENPKESPLRHRRIPTPSRVRSMRQGNYPAEQRLPKNDLPGAQSKGFPHWEGTTITADARKSDEISVMTPFGGDAQRNYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEX6</accession>
    <name>A0AAD8YEX6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">AspA/AstE family protein</fullName>
            <ecNumber evidence="6">3.5.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_004738</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEX6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050178">
        <property type="entry name" value="AspA/AstE_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055438">
        <property type="entry name" value="AstE_AspA_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15162">
        <property type="entry name" value="ASPARTOACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15162:SF7">
        <property type="entry name" value="SUCCINYLGLUTAMATE DESUCCINYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24827">
        <property type="entry name" value="AstE_AspA_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Succinylglutamate desuccinylase/Aspartoacylase catalytic" evidence="5">
        <location>
            <begin position="7"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1744205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="251" mass="27891" checksum="92FF2460800F5508" modified="2024-05-29" version="1">MLFDSLTIEFMLGNPAALRQNRRFIQRNLNRLFDINTLCDSDLADQEGYRYELHRARLITESIRHADFVLDIHSCSSDVGSFALPSSLDLSELLAEHLPVKYVVESLVHACLDGGTTLDAALWNDVPGVCVECGQHTHKDVAMFTVSRAAAVISSFLRLQVLQEDGAFATPSSQSLVKPITMVCTNVERVSIGFQWLKKFPEFHFVAEEEPVFRDAERGVVKCPVEGGAFIVMPTAQPVMGEEALFWASAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFJ0</accession>
    <name>A0AAD8YFJ0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_003523</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFJ0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1745599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="102" mass="11492" checksum="ED6939C0E80F9573" modified="2024-05-29" version="1">MLLVGEVEEDEEKQLYHLEEAAIRGHPNARYNLACLEKWNNRFDRAVKHHIIAANLGYDLSIQALKDFYKDGLVSKEDFAAALRGHQAAVDATKSPQREAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFN1</accession>
    <name>A0AAD8YFN1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histone-lysine N-methyltransferase, H3 lysine-79 specific</fullName>
            <ecNumber evidence="1">2.1.1.360</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Histone H3-K79 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_003342</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-lysyl(79)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(79)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:60328"/>
            <dbReference type="Rhea" id="RHEA-COMP:15549"/>
            <dbReference type="Rhea" id="RHEA-COMP:15552"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="2.1.1.360"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.360" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFN1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140956">
        <property type="term" value="F:histone H3K79 trimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025789">
        <property type="entry name" value="DOT1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030445">
        <property type="entry name" value="H3-K79_meTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21451:SF19">
        <property type="entry name" value="ACTIVATED IN BLOCKED UNFOLDED PROTEIN RESPONSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21451">
        <property type="entry name" value="HISTONE H3 METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08123">
        <property type="entry name" value="DOT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DOT1" evidence="6">
        <location>
            <begin position="84"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1745418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="254" mass="29228" checksum="B1E8E939E0470CB2" modified="2024-05-29" version="1">MSKSTENLYSLLKDGVNDKNTRGEANRIITDDLHQLAQKKVLHELDSLYEEYTFATAKDASLTDDLQRRISKNNVTCEHEHTEDSLVYGEIDLKGFCDLLMHHIPHDSDDVFYDLGSGSGRAVFAARFVGDFRECVGIELLSNLHEMASSVRSLYRFQYQHKLIYQNVNFVCSDLLDYHGWWKDGTVVYIPNLLFDDNLKDKIAEKAVRMRTGAFLICLKKFEGAAFNSVFDLVKERPVAMSWGESNTYIYQRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YH09</accession>
    <name>A0AAD8YH09_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Calmodulin-lysine N-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004453</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YH09"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042096948" description="Calmodulin-lysine N-methyltransferase" evidence="2">
        <location>
            <begin position="26"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="355" mass="39453" checksum="A02984D688D7D5FD" modified="2024-05-29" version="1">MKSIAHLSLFVHVILFLHRLHLCFSFSIAGRRLLPTEMRSVAGDGDGDDNGGEHGTGLRRGTTYSWANPKLQTTKDSAKQSGNHTDPEYKRIQFGGCGSILVHSGTSSRVTSLQHTGLSLWSAAYVMSYYIDDMWIQDIKCSNNELNKWTVLDLGAGLGLCSAVAAKHGMNIISTDSDSQALVLLEENVRRNCNEDNGNTSVHTLDWISAAEQADMTTNPVFEELEKYGGSDLVILSDVIYSATKPAWKALIVLLQKLRSQRMRLLCNSPATVERKRCDSTHTPASDPLVLLSYTQRRRDMSPQDEAEFFTMLRKAGMEAVLVPSGQIPHGETYMLTTLFELRWVISFKKCDGFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHH9</accession>
    <name>A0AAD8YHH9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHH9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051279">
        <property type="entry name" value="PP1-Reg/Actin-Interact_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24112">
        <property type="entry name" value="LEUCINE-RICH REPEAT, ISOFORM F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="394" mass="44123" checksum="F24224BE73B4FC41" modified="2024-05-29" version="1">MDSDSDDNNGSGSEASHSGSGSESEASLHNESSSSSDDDDSVEQFNVNLQRVRENEFNVNLQRVKVNDPEATELAGNGRYNCIEHMTDEGWEQLGRDISNNTHLKDVYLYEGAMNDHKMSFFYRGLTRSNSIQLMALYENNLSIAGVRSMVPFLQKNNLKGLNISDNDILSEGLNLLFQALSDSPIEDLRVTNCSIESIALASGRLPRNLKHLHLDWNNIKINADGRNGLAKLLQGGHSTLKGLWLSNNKIDNEGVAILVDILRSNTTLTTLALEHNNDITYDGEMLLLKLVNNLSSIKATLQSNHTLTNLTMKEINPYGEYPYQNDLSEEFQMNINVATQINANEGNLVAAGREKVVVSHLDSQIRLELYCLQDLDDSLYSQIDPFIYLRYFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIN5</accession>
    <name>A0AAD8YIN5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Roadblock/LC7 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002846</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GAMAD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIN5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004942">
        <property type="entry name" value="Roadblock/LAMTOR2_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10779">
        <property type="entry name" value="DYNEIN LIGHT CHAIN ROADBLOCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03259">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00960">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103196">
        <property type="entry name" value="Roadblock/LC7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Roadblock/LAMTOR2" evidence="2">
        <location>
            <begin position="9"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="105" mass="11973" checksum="3612AF179B08C035" modified="2024-05-29" version="1">MAHNQANQVDEILKDLQSTPGFKAYIILNSDGIVIRHTMDSNERAVQHAHHITELYNDSVAQIKDLFDHPEDSRVENVRMRTENYEMIVSSVGSFTLAVFQEETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIN7</accession>
    <name>A0AAD8YIN7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sel1-like repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_002620</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIN7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="7">
        <location>
            <begin position="24"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="163"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="590"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="597"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1747276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="609" mass="68995" checksum="E6BDF1232E015116" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKN7</accession>
    <name>A0AAD8YKN7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000298</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKN7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.90">
        <property type="entry name" value="Protein of unknown function DUF1823"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014952">
        <property type="entry name" value="DUF1823"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43948">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43948:SF10">
        <property type="entry name" value="MRJ, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08853">
        <property type="entry name" value="DUF1823"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="10"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="520" mass="58300" checksum="D30B4DDAAD613C9C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLI7</accession>
    <name>A0AAD8YLI7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase FkbM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001373</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLI7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase FkbM" evidence="1">
        <location>
            <begin position="160"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="278" mass="30590" checksum="15DA842A9BF636A2" modified="2024-05-29" version="1">MEFMNHQPELIYKLLPAELLDRDVKQKKYYVAVDLGSNLGYYSMLLASRASPDTAWLQRSSAALNGLLLSTLTTQSAVSHGGSLTIVDRGVTDEPTIGRLSRHSDSPGMTSFSAGGKFDLKTGDAGTALDVDIQLVRAKDVLEELGIPPTIKATPKDEQSHILHLLKIDVEGFELKALKGLDLDLYRFRHIVMEYFPDMLRGAGTDPPEVLLYILSHGYTFYEIVGSTGELREINVGDNDATGLRDWAENAEKKSGSGFHINLFASIALEDLEGFIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLT4</accession>
    <name>A0AAD8YLT4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Rubredoxin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_001538</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLT4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043448">
        <property type="term" value="P:alkane catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00730">
        <property type="entry name" value="rubredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024934">
        <property type="entry name" value="Rubredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024935">
        <property type="entry name" value="Rubredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050526">
        <property type="entry name" value="Rubredoxin_ET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47627">
        <property type="entry name" value="RUBREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47627:SF1">
        <property type="entry name" value="RUBREDOXIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00301">
        <property type="entry name" value="Rubredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57802">
        <property type="entry name" value="Rubredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50903">
        <property type="entry name" value="RUBREDOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042058337" evidence="7">
        <location>
            <begin position="21"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Rubredoxin-like" evidence="8">
        <location>
            <begin position="109"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="57"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1747575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="210" mass="23258" checksum="3B66D5A989B30A3D" modified="2024-05-29" version="1">MMPRIEVFAAVLALLTGSVAFAPASVPTRGISQRCVQQFVEKNLQHQQRTHLLRPLRMSETEEASAAPVAEKEEEEEEAPMDAATKLAIEKQKRADELRAQEVFMKRSTGLHKCGNCDWEYDPEKGDSFLIGGMIKPGTEFADLPSNWRCPTCRASKDNFEEVVETIPGFEVNQGYGFGTNSMTSGQKNTLIWGGLAAFFILFIGGYAMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLV3</accession>
    <name>A0AAD8YLV3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">50S ribosomal protein L28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_001568</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLV3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.40">
        <property type="entry name" value="Ribosomal protein L28/L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026569">
        <property type="entry name" value="Ribosomal_bL28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="Ribosomal_bL28/bL31-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037147">
        <property type="entry name" value="Ribosomal_bL28_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L28, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL28M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00830">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="L28p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041981255" evidence="4">
        <location>
            <begin position="18"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1747605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="123" mass="13634" checksum="6B511760319DFA98" modified="2024-05-29" version="1">MKTVFALLLALVASAAAFTGTPLQLTRSSPAAVRSNARSTLVMRERACDLLGKTANRKARVVTFSHKRIHKVQQVNLQWKRFYSDDLGRQVRLRLSTKGIKTVNKYGSIDAAAKKFGVNLGKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMJ6</accession>
    <name>A0AAD8YMJ6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Helicase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000681</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMJ6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001497">
        <property type="entry name" value="SNF2 family DNA-dependent ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10799">
        <property type="entry name" value="SNF2/RAD54 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="65"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="252" mass="28546" checksum="64D38A55F862C9F6" modified="2024-05-29" version="1">MNYGYFGNDASLTLGLVKEELDKFSDYDIHCACEEMISENSARRQLLGKYTLLQDDLFSSSKFVRLRHLLPDLIKKGHRMLIFSQWTKVLDLMLNLLGSLELSCLRLDGSTPVSERQALIDKFNNDQSIPVFLLSTRAGGMGLNLTAADVCILHDLDFNPFNDLQAEDRCHRIGQTKPVTIIKMVTQGTVDEDIYSIQERKARMNKAIMEENGKKKSKKESEELCAIALNAVENFKRSKEDDETEAIDLTST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YNM1</accession>
    <name>A0AAD8YNM1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_000549</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YNM1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43736">
        <property type="entry name" value="ADP-RIBOSE PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43736:SF1">
        <property type="entry name" value="DIHYDRONEOPTERIN TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041901607" description="Nudix hydrolase domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="Nudix hydrolase" evidence="4">
        <location>
            <begin position="62"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1748610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="199" mass="21978" checksum="C2D2B1C4AF3ED7BC" modified="2024-05-29" version="1">MAPLLLIAALLCFLNNLSPMDALMTSTTIHFARNSFMHKSKVPTIASRLMSASSSNNNVPSYPRAAVSVVIRFHDASPSSSASTPSTIEPVRYLLIQRGKAPNKGSWSFPGGKIESDEATMDAAKRELREETGLGDSTQHTQQWTLKWYDDGPFTCSDAIADGFHYVISQCFAELSHHHSQILKHRMTPWMLNGGVQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YNU7</accession>
    <name>A0AAD8YNU7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chalcone isomerase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YNU7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016872">
        <property type="term" value="F:intramolecular lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.890.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016087">
        <property type="entry name" value="Chalcone_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016088">
        <property type="entry name" value="Chalcone_isomerase_3-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016089">
        <property type="entry name" value="Chalcone_isomerase_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036298">
        <property type="entry name" value="Chalcone_isomerase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47698">
        <property type="entry name" value="FATTY-ACID-BINDING PROTEIN 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47698:SF2">
        <property type="entry name" value="FATTY-ACID-BINDING PROTEIN 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16036">
        <property type="entry name" value="Chalcone_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54626">
        <property type="entry name" value="Chalcone isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chalcone isomerase" evidence="1">
        <location>
            <begin position="41"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="229" mass="23976" checksum="079317CE8FC07813" modified="2024-05-29" version="1">MAIKVATVGVAVVAIIAAIIMGPTAFLGGDVDISGSDNNLTVDGVAMPTQIKTSGTLQNFIGGGLRMKWGFKVYVVGIYSDPKVMTSLKKKYSGFEAKDSNLSDLATDFAKSKPARTVLLRFQRSVAASDISDALGEALKPKVGAASDEFQKFILDMVGSDRLEKGSDIYITCKGETLSASLTGGNDSSSIRIKGLCPAVFEVYLGDKAVSPQAKKGFAEGVATLMASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPV7</accession>
    <name>A0AAD8YPV7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001151</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPV7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053211">
        <property type="entry name" value="DNA_repair-toleration"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48060">
        <property type="entry name" value="DNA DAMAGE-REPAIR/TOLERATION PROTEIN DRT100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48060:SF21">
        <property type="entry name" value="L DOMAIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="52"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1749212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="660" mass="71740" checksum="07CDED59F0E0C9ED" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3B7</accession>
    <name>A0AAD9D3B7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_016993</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000073">
        <property type="protein sequence ID" value="KAK1732326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3B7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052394">
        <property type="entry name" value="LRR-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114">
        <property type="entry name" value="LEUCINE RICH REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1732326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="405" mass="44530" checksum="37F3519A63D47EA6" modified="2024-05-29" version="1">MMMYIEPVSEQRINVTTQVNIYLTGVPSNQNMTTTEQEVFESLFYTLLQSRLETVDVGILEVVVDAQINDPQFDADSPFDSSQSDTNNGGGETKLLSSVLQLVTNVTLTYSDPPPEGWRDWSIYLTSWIESFGPTMVDIFTDPKHKLYPNQEFFNTISDVSGTNVVPPNTDPTMSPTLAPTYLGAPEYKKPLVTGWQLRMAALALALNENTSISRLSLQSNMFTSEGVEYLIVCLVCNSTIDVVDLEGNSPIDPRILDELCGILQSRGVPNHSNKLELLLERIRGNDPNLTQLDLRGMGIGQEDNDAIMDALAGNAYLRKVDLSDNMIDDDGVSALSLALADNTSITHMCLAENRITSIGAEYLLCALDTNDTIVDVDLAGNSIDAGVMDELNHALKQRRTVDGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3S4</accession>
    <name>A0AAD9D3S4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_016673</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000062">
        <property type="protein sequence ID" value="KAK1732612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3S4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1732612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="277" mass="31299" checksum="273CFB58141BF9A1" modified="2024-05-29" version="1">MDHAVDFNYDDIFVYMGGRVPRHLRAHITRAIVDQSISVVDEYAFYNCTRLRSLECHEGVDRIRKRAFMNCTGLRVAKLIGVKFIEMEAFELCTRMLDIEFGGDLRTIGRRAFSNCNSVRRLRLTSTSVVSIEKLAFENCGRLVDVALPEGIDTVRGQAFSGCINLRRITIPLKTGMFSPDSVSYILPPRSVFDWCERLSSVELVGRIHQSVSYLSLDCWKIGMSEEFDRINDILHSLASRRVENHGNQTMDGVCATPFGTLQTRASSIIERGCSPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D429</accession>
    <name>A0AAD9D429_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_016158</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000053">
        <property type="protein sequence ID" value="KAK1733181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D429"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035770">
        <property type="term" value="C:ribonucleoprotein granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000963">
        <property type="term" value="P:mitochondrial RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044528">
        <property type="term" value="P:regulation of mitochondrial mRNA stability"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050870">
        <property type="entry name" value="FAST_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21228">
        <property type="entry name" value="FAST LEU-RICH DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21228:SF40">
        <property type="entry name" value="LD45607P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="280" mass="31241" checksum="C40443B5AC3FEBD9" modified="2024-05-29" version="1">MKSNRKIFQFFAGASMDIIREFDERHLSNLAYAYALIDYVPEFDDGIDLFDHITMNAVDVKAEFIPQGIFNMAWAYATIGKPHAALFEAMGDQIVASNLLKEFRPQALSNTVWANATVDVPHAKLFEEKVANLIVQSKSLARFNSQDLSNIVWAYAAAQFPHPKMFRKVAEAAIRSKGEFISQDVANLLWSNATMVITDKQLFLSIAPTAAKVIDSCTNQELSNIAWSYAVADVDAPTLFMIISSISVSEWKARLKLRKSSSSTSGICGRRKRSQIPGYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4A8</accession>
    <name>A0AAD9D4A8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015866</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000049">
        <property type="protein sequence ID" value="KAK1733451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4A8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="117" mass="13238" checksum="BA5E07E48B96821E" modified="2024-05-29" version="1" fragment="single">LQTSLTKISEIPPLLQNAEWDRVRTILKTPPVNSLWNLGESSNTIVKLAKETGEFDLLELKDELAISLQMTDQYSYDNVFIYYQPGNGKVKTKEPLEMANKAIVQLKEVVDVASKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4E2</accession>
    <name>A0AAD9D4E2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_016740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000063">
        <property type="protein sequence ID" value="KAK1732599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4E2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1732599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="210" mass="23253" checksum="E8353A6DE89D535A" modified="2024-05-29" version="1">MTLTSPSRQGGGAIATLKCPSCNSEHHAKTDIFGNRYKHCSDEGSDFGVLELFGAKAKCAICLETCEDIVGLPCGHCLCKSDYKRMGGIVRAFNEDEHQNRGECDDDVIVTVKRAGKKEVNGTYKKDCNRYTRSARYDGKDVEYSIEKRVVNGKKMWVLCCRSEEGKEDPVDFYRATVNETCEYPSSVKWVSTLIGSGPAPRSEVSYFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5H6</accession>
    <name>A0AAD9D5H6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000045">
        <property type="protein sequence ID" value="KAK1733678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5H6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="246" mass="27833" checksum="3D47DE03B13D05EE" modified="2024-05-29" version="1">MTKTSHNVKAAATDITETAALSEYEAARARNIERNNARLRSLGLISILEERKSNDIAWGRDIVETKHDSSSDEESSSDEEYSEGNQSSTKKRRKRRAKSNNMPPREGSRKSRRLMNLPSEHTSETIASEDPTERRERIRQERLAMVEECREARQRAALEVAKAGVKLAGKENPTATYEHCLMRVRSMTEKGLINRVRAIERAAGKHCVVKMAIFKSCLQDEDMWELAQLASDALERLKALLPPPSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D696</accession>
    <name>A0AAD9D696_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">tRNA (guanosine(18)-2'-O)-methyltransferase TARBP1</fullName>
            <ecNumber evidence="8">2.1.1.34</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">TAR RNA-binding protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_014767</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 18 (Gm18) in a subset of tRNA. Selectively mediates Gm18 methylation of tRNAGln-TTG/CTG and tRNASer-TGA/GCT. Gm18 modification can enhance the stability of modified tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>guanosine(18) in tRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(18) in tRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20077"/>
            <dbReference type="Rhea" id="RHEA-COMP:10190"/>
            <dbReference type="Rhea" id="RHEA-COMP:10192"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74445"/>
            <dbReference type="EC" id="2.1.1.34"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:20078"/>
        </physiologicalReaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.34" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000038">
        <property type="protein sequence ID" value="KAK1734519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141100">
        <property type="term" value="F:tRNA (guanine(18)-2'-O)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18091">
        <property type="entry name" value="SpoU-like_TRM3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1280.10:FF:000010">
        <property type="entry name" value="probable methyltransferase TARBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045330">
        <property type="entry name" value="TRM3/TARBP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044748">
        <property type="entry name" value="Trm3/TARBP1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12029:SF11">
        <property type="entry name" value="METHYLTRANSFERASE TARBP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12029">
        <property type="entry name" value="RNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="1 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="tRNA/rRNA methyltransferase SpoU type" evidence="12">
        <location>
            <begin position="1706"/>
            <end position="1847"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="438"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="507"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="11"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="441"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="508"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="519"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00093266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00093361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00093594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00093636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00093656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1734519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1860" mass="204177" checksum="6A1D9EEC6C0DFBB4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6A4</accession>
    <name>A0AAD9D6A4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MAP3K-like serine/threonine kinase</fullName>
            <ecNumber evidence="3">2.7.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014046</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6A4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="499"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="449"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="140"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="810" mass="87832" checksum="1E083EF04362BA16" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6C1</accession>
    <name>A0AAD9D6C1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_013452</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6C1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="554"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1735746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="591" mass="66690" checksum="D809ADEA9C3C5C82" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6J3</accession>
    <name>A0AAD9D6J3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Formyltetrahydrofolate deformylase</fullName>
            <ecNumber evidence="4">3.5.1.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_013122</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.10" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1735986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6J3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008864">
        <property type="term" value="F:formyltetrahydrofolate deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08648">
        <property type="entry name" value="FMT_core_Formyl-FH4-Hydrolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.170">
        <property type="entry name" value="Formyl transferase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01927">
        <property type="entry name" value="PurU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041729">
        <property type="entry name" value="Formyl-FH4-Hydrolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004810">
        <property type="entry name" value="PurU"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004684">
        <property type="entry name" value="PRK06027.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00655">
        <property type="entry name" value="PurU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42706">
        <property type="entry name" value="FORMYLTETRAHYDROFOLATE DEFORMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42706:SF1">
        <property type="entry name" value="FORMYLTETRAHYDROFOLATE DEFORMYLASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01575">
        <property type="entry name" value="FFH4HYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="Formyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Formyl transferase N-terminal" evidence="3">
        <location>
            <begin position="142"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1735986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="338" mass="38524" checksum="16776D5D0F409DA8" modified="2024-05-29" version="1">MATIFGAQRLIIKLKLRHITKASSSGLLCRRQFAGLANEANATKEARLLLAGPDARGIVASFSHLLFSRGCGIVDCTSESSEIDAKVDKRGQHSRRMFFQRILFDYSNVSVERDVIEDEINDLCVRFGMESQLSWGGDKRRRIAIFVSKYDHCLWELLLRQRAGELDCEIAMVISSHEKLRHVADTFDIPYHVFPITKDNKLEQEEKQISLIEQHNVDLLVLARYMQILSPSFCSRFQNQIINIHHSFLPAFRGGSPYHKAHERGVKLVGATAHYATTELDEGPIIEQDIMRVSHRDDVKDLVRKGRTLEKTCLTNAVKAHLDDRIITHRSKCIVFAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6T7</accession>
    <name>A0AAD9D6T7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosome biogenesis regulatory protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_014081</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in ribosomal large subunit assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the RRS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6T7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007023">
        <property type="entry name" value="Ribosom_reg"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04939">
        <property type="entry name" value="RRS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="261"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="376"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="451"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="31"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="397"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="456"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1735015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="477" mass="53196" checksum="B2A4EFBA35991421" modified="2024-05-29" version="1">MARRKATARMSKKKEVEVEEASTSSASVAESEAEEESDTNDHSEEEEASDVQSEEEEEGSDEEVNSSDEESSGEEESDDESPENSDDVNTDSVGQNEQCTFDLGNLLSFNTHQVNAAELYRGGSMKNNLNKEWYELRPPTIEASKASALPNPVNESMLLAKAAEGTTQLLRELWKLPTEKTDLGLLAKLPTAETRLPRMLPPPPPKQLTKWEQFALQRGIAPKGKQSRKVFDEATGEWKHLTGSLDNKANAGPESWPILEVKKNDDPMQDPWEKLREEKKSRVGKNTESRMRNAERAGNLEKGTANRMMKNVKKQEKQKVLMRQKEREMGLVAPVGVPVDMRSGGEKAQRGKPSTQLALKATQTSTASLGRFDKQIEGEPERQLNKNTKKRKLDPSVTGNTNKKYLQTEAQKSQDILSKVMNGSKQKDKDVKKGKYAKGETAYDYDFDDGLGSGSFKKKKGRAGAGKMKKLTKKRIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6U6</accession>
    <name>A0AAD9D6U6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">Glutamine synthetase</fullName>
            <ecNumber evidence="2 9">6.3.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_014095</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 9">
            <text>L-glutamate + NH4(+) + ATP = L-glutamine + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16169"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.1.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the glutamine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.2" evidence="2 9"/>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6U6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamine synthetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.590.10:FF:000004">
        <property type="entry name" value="Glutamine synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="entry name" value="Glutamine synthetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.10">
        <property type="entry name" value="Glutamine synthetase/guanido kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008147">
        <property type="entry name" value="Gln_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027303">
        <property type="entry name" value="Gln_synth_gly_rich_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027302">
        <property type="entry name" value="Gln_synth_N_conserv_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050292">
        <property type="entry name" value="Glutamine_Synthetase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20852">
        <property type="entry name" value="GLUTAMINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20852:SF57">
        <property type="entry name" value="GLUTAMINE SYNTHETASE 2 CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03951">
        <property type="entry name" value="Gln-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54368">
        <property type="entry name" value="Glutamine synthetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00180">
        <property type="entry name" value="GLNA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00181">
        <property type="entry name" value="GLNA_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51986">
        <property type="entry name" value="GS_BETA_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51987">
        <property type="entry name" value="GS_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042232591" description="Glutamine synthetase" evidence="10">
        <location>
            <begin position="17"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="GS beta-grasp" evidence="11">
        <location>
            <begin position="63"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="GS catalytic" evidence="12">
        <location>
            <begin position="154"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1735029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="416" mass="45659" checksum="28EF0E2AB39B7B00" modified="2024-05-29" version="1">MKLAVAFLATIGATAAFAPAANTVARTSALNMVQQLDLKTGQSQLDTSVVDRFNALPYPDDKVLAEYVWVDAKGECRSKTRTLPVARTEAVDKLPRWNFDGSSTDQAPGDDSEVILRPCRIFKDPFRPRADGLDNILVMCDTYTPAGEAIPTNTRAIAAKAFEGKEDEEVWFGLEQEFTLFNLDQRTPLGWPKNGVPNRAQGPYYCSAGPENSFGRAVTDAMYRCCLYAGLEISGTNGEVMPGQQEYQIGPCVGIDAGDQLFMSRYILQRVCEEFQVYCTLHPKPIVEGDWNGAGMHTNVSTKSMREAGGLDIIKQAIYKLGAKHQEHIAIYGEGNELRLTGKFETASMDEFSFGVANRGASVRIGRDTEADGCGYFEDRRPSSNADPYLVTGKIMATIMEEVEVPEIAPLNRAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6V9</accession>
    <name>A0AAD9D6V9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014443</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6V9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="60" mass="6548" checksum="FA2CC249BE4986D1" modified="2024-05-29" version="1">MPSFNGRVIRSREVQRANAHASILSSLIPNFTSVRASQLSNAPPLTILADGRLMLLKDSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6Z2</accession>
    <name>A0AAD9D6Z2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_014154</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6Z2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="34"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="448"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="162"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1735088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="515" mass="58772" checksum="9EBE4AB07D259B1E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D890</accession>
    <name>A0AAD9D890_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Peptide deformylase</fullName>
            <ecNumber evidence="2 3">3.5.1.88</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_013070</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Removes the formyl group from the N-terminal Met of newly synthesized proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>N-terminal N-formyl-L-methionyl-[peptide] + H2O = N-terminal L-methionyl-[peptide] + formate</text>
            <dbReference type="Rhea" id="RHEA:24420"/>
            <dbReference type="Rhea" id="RHEA-COMP:10639"/>
            <dbReference type="Rhea" id="RHEA-COMP:10640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:49298"/>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
            <dbReference type="EC" id="3.5.1.88"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the polypeptide deformylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.88" evidence="2 3"/>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D890"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042586">
        <property type="term" value="F:peptide deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00487">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.45.10">
        <property type="entry name" value="Peptide deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00163">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023635">
        <property type="entry name" value="Peptide_deformylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036821">
        <property type="entry name" value="Peptide_deformylase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00079">
        <property type="entry name" value="pept_deformyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001159">
        <property type="entry name" value="PRK00150.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458">
        <property type="entry name" value="PEPTIDE DEFORMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458:SF22">
        <property type="entry name" value="PEPTIDE DEFORMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01327">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01576">
        <property type="entry name" value="PDEFORMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56420">
        <property type="entry name" value="Peptide deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041997009" description="Peptide deformylase" evidence="5">
        <location>
            <begin position="21"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="246"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="248"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="262"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="278"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1736470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="315" mass="35459" checksum="0C19D442CB0647E7" modified="2024-05-29" version="1">MKIYNRLALLIALFASPADSFSGSYQRLSNVVSNQHSFVMRLNPTSFQGTDFVITEYPRPALRHVPNKSISEFDDTFQAKTQEMLMIMYESKGVGLAAPQIGLSENVFVYNPSDSKNMERVVCNPKITKYSEEVIVEQEGCLSLRSDECAGQVARSKWIETEYQNELGQKVIRRLKDFEARVFQHEFDHLKGILCLDRFPPEDREAAQENINKLLGLYTDSDAAADPDEEEFNSMMPRPLSARYMPPLEEEEEEEQEQPVGKSGGFGGGGFGAGGGKKATKKKKETKKKVKARDGKRSDNPMFKKTGKTGFANRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8I8</accession>
    <name>A0AAD9D8I8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8I8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="305" mass="33277" checksum="94357636FD4AB392" modified="2024-05-29" version="1">MTSLKSSSNQITAVNSSGARRKRRHDDVINNNWLKRMFYLCVFIFVLFPLLSIFLATIFGGLLAWAENTTFLNGFLYVVSNLLGMANPLTNWEPTTGTGVVIVIDIYTAVAALISFGIMLNVVNLFRVPHEMNNLIRKVVTNGFLVPTIALGIIIPAWYAGLCSIMGAILALAENWHVSEGILYVLSNILGLANPLTDVSPNKTAGQVIDVVISSIALGYIAIFADYVTTLNPSSYVRFKIRGYLIALGVVDADSTAIAHPLRQLSITNDGEYDDKEEEEGIETKHSKSLLVGSFPVMSTDVSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D905</accession>
    <name>A0AAD9D905_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA pseudouridine synthase, RluA family</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010731</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D905"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluA-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050188">
        <property type="entry name" value="RluA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600">
        <property type="entry name" value="MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600:SF87">
        <property type="entry name" value="RNA PSEUDOURIDYLATE SYNTHASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="2">
        <location>
            <begin position="121"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="350" mass="39082" checksum="3D9DB25FE86767EC" modified="2024-05-29" version="1">MSQEYKDESLHRILCKMDPDTFPSASQSRKAIEHGRLVVLRADDYCLCASASGGTTLDSTISNVGIIADSSITLHDGDVIAIRSRLDNGSYPQSCTKYVDPPTNIKDFLAVENSVLFEDDHIAIVNKPGGLDCIGEKRNDLQSILPFVLRPPDNKTTKNNPSSQYYIPRPVHRLDRKTSGCVLVAKSKNAMRQFSHLFASRQVKKSYCAITFGMPTPFDKNNSTTIDGEEYSIIDYPIDGKDAVTLWRVVQTVTTKKYGKLSLLHCLPKTGRNHQIRRHLSYCLKTSIVGDNKYDGGGDMAKKTRELGMFLCSNRIEFVHAIDKSNVSIEIPIPHKFSALLELNRIEVVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D956</accession>
    <name>A0AAD9D956_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011716</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D956"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="401" mass="45492" checksum="715D8DF820F0F6FF" modified="2024-05-29" version="1">MTMMLHHRSNSSQTHPRRKAILSLCSIGFFLGVIILFSHQLENNLDHQLLDTRNNALRSSSSPWSSTHNFDDADDVKKVSYVTSFWAKERHTTIHPHPHRREIEAALLANIYNPHIDQVVVFLDGVTTDDNVEEEFKSSCVHFHQDMAEINRQFLHTSSSTNTHGVDPMSKVTCVNVITGQPTYHQMFLNALSNVVTGDIVIVANADMAFDDSISKARKLKEDVLLVLGTRGFSQDAIPVSTRQFYDIIARAENQQLKDSVLDQCKVNPRTWDTWIFHKEAIQGQLQEKHFQRPNNNNEMTSFYMNENGAENAALWAVEQCPSLATTYNACDEVLSWSFHLSAKTHHSQGQTIWPKGDGGVGQNPNSVFVPEPWGGSERKKWKSPPYPPKWCKRENGCFFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9M3</accession>
    <name>A0AAD9D9M3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9M3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="220" mass="24015" checksum="B425FC45B35CFF54" modified="2024-05-29" version="1">MVSFVERQLHDGTPRASYLRIVALVDRLLVLSALTNKAGESEGQVICSKLTFLMDGMDSVMKARTYFALGCFYGSSGSLTKAKAYLEMARNLFQEAEDDNSSVRDIADIEIKLNGINSSSDVDSLRSRYEETLAKSGRETTLTIDAGVALAKALHGSDRNIEAEKLLANLLATSRRVHGQDHRCTKSAATALQGLTNELLEDPRSTDSGFGDVDGWFRSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DB51</accession>
    <name>A0AAD9DB51_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008278</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DB51"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="185" mass="19936" checksum="412F5F1C042F3629" modified="2024-05-29" version="1">MPPRRRRGGGGRGGGLSGRGRGDRGGGLSGRGDGGHRDRGRVGRGRGGGFHRIRSDVNENNRPRTRRRIAEEAAAASSNSSTHNSTPAATPSIRDNARDPSSSTGSQHSQDSSTSFYNLEYHHSRNESSMTGGGTNLNTARLNPRICICDCDESSMFGRVDIAWFNMQLKNIEDATPQLRAETII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DB89</accession>
    <name>A0AAD9DB89_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DOMON domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_009951</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DB89"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042147113" description="DOMON domain-containing protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="353"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="261"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1739408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="374" mass="39891" checksum="238DF974A0486C51" modified="2024-05-29" version="1">MNKLSCAAILLASAAVGTQAQDMCSCSPTTFNFLLDFSNNCEVNTIDGNPGVQTAMCFQEVVDAVPGQPASDEPMRRLLRESEHDEDEPRSLQTGEDKVVEVVSAQFLEFGTDGDMTVIHQDNTYTTTSLLDGGAMQFDSVSSKLDTSVPLSDQMENPALVPGGASLILYGKTESGKVIRNRFFWLYEMSNCGRENKPVQVGDQIGWVKVEPGPLGGAWPAFCPALPDGSPTISPRTNDPTLTPSSAPIEQVPTVTPTAKPVITDTPVTTDAPTDAPQSSSLIPGPSPTRKPTHPVFGSKSAKSKSLKPPHSAKSSKSKSAKNSSKSSKSNYHGYLNAHIVYEDFKMMNSSSMLSSFGISLITLAVTFYLSGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBR3</accession>
    <name>A0AAD9DBR3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009722</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBR3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1739963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="131" mass="14613" checksum="3D5A88DB08E9D0D0" modified="2024-05-29" version="1">MRVLIITPRNIRITQEQFEIIHSFQLTPRPLLPLKLLRQPPLLITLELLHPFLLVGAKAQFFLVAPEYRVGLRDALGFGHVGCAVQDLVEVRDLIFAVVAYEEEEGAGVGLDGVPEEGADSFVELFADHLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DC25</accession>
    <name>A0AAD9DC25_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dynein light chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DC25"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="431"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="163"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="233"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="288"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="485"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1097" mass="121040" checksum="E7D3C02297CB749B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDS1</accession>
    <name>A0AAD9DDS1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6824 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005204</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDS1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049227">
        <property type="entry name" value="DUF6824"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20710">
        <property type="entry name" value="DUF6824"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6824" evidence="2">
        <location>
            <begin position="59"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="127" mass="13770" checksum="69B4CDFFB8C0E11A" modified="2024-05-29" version="1">MNTSPPPNVQDPSGAAAAFPPLPSPIMDPAASAHHAQQQPVQVAAPVAANNEIQVSHQDVLFGRGGQTNRHIGNLRYRDIIALHRADYVRASKVEKPNVARRIVQAIRTGKNPGRFLRKATMENGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DE48</accession>
    <name>A0AAD9DE48_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Elongation factor Tu, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_004829</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DE48"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070125">
        <property type="term" value="P:mitochondrial translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01884">
        <property type="entry name" value="EF_Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03697">
        <property type="entry name" value="EFTU_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03707">
        <property type="entry name" value="EFTU_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000001">
        <property type="entry name" value="Elongation factor Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000003">
        <property type="entry name" value="Elongation factor Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_B">
        <property type="entry name" value="EF_Tu_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041709">
        <property type="entry name" value="EF-Tu_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033720">
        <property type="entry name" value="EFTU_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004541">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_bac/org"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00485">
        <property type="entry name" value="EF-Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000766">
        <property type="entry name" value="PRK00049.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009372">
        <property type="entry name" value="PRK12735.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009373">
        <property type="entry name" value="PRK12736.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF22">
        <property type="entry name" value="ELONGATION FACTOR TU, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="7 11" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="10">
        <location>
            <begin position="76"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1744296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="462" mass="50970" checksum="179AA782D04915B3" modified="2024-05-29" version="1" fragment="single">ISPLSLAPSQIQHVRTIIAFLDPTRLCATISPNMNRFATSIAQQSSKRVLSSQYAPGLYVTRRSFAAAGDKFNRDKPHVNIGTIGHVDHGKTTLTQAITKVLSEKGWSKAMTYEDIDRAPEEKSRKITINTSHIEYETATRHYGHIDCPGHADYVKNMITGAAQMDGGILVVAATDGPMPQTREHILLAKQVGIPKLVVFLNKCDMVDDEELLELVEMEIRELLDFYEFDGDETPIIRGSALAAAEGRDPELGANAVLELMQAVDDNIPEPERDMDKPFLMPVEDVFSIAGRGTVVTGRIEQGKINVGDDLEVIGFNNNQKTTCTGVEMFKKLLDYGMAGDNVGALLRGLKREDVRRGQVLCKPGTLSTATKFEAEVYCLNKDEGGRHTPFFSNYRPQFFFRTADITGDLKLREGTEMVMPGDNTTMDVELITPVPIEAGLRFTMREGGRTVGTGIVTKIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEN3</accession>
    <name>A0AAD9DEN3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEN3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="229" mass="24881" checksum="83433E4984053E2E" modified="2024-05-29" version="1">MSQVRNVPSKRVVVEHRIEEEMIAPFVTKAAVQSAAALPQSPAAFIAAIPRGGAVAAAAAFDMGLAKTRLEGLAYGTVTALITSAALNLFKFADGKNCKLIANDRFNNILKITFGILLASTVSLGIYTTAIFTIIGIYSKTALGMGQTTDFITFFNSCEKFRHYGFRSFVACLASFSISWVCALLLTYEEETRWWIALPAILVGVMGFLHYKELFALASTLIYSSSCEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DES5</accession>
    <name>A0AAD9DES5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005085</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DES5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="79" mass="7498" checksum="A56EBB25931F9421" modified="2024-05-29" version="1">MANLATANALATTELLNARLFEHISGGSGSGSGADNDTVGAAVERVGSGVTASAAAAAAVGPPDSFASLYALNYGIGGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFD4</accession>
    <name>A0AAD9DFD4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Syndetin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990745">
        <property type="term" value="C:EARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019514">
        <property type="entry name" value="Syndetin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040047">
        <property type="entry name" value="VPS50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13258">
        <property type="entry name" value="SYNDETIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13258:SF0">
        <property type="entry name" value="SYNDETIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10474">
        <property type="entry name" value="Syndetin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Syndetin C-terminal" evidence="2">
        <location>
            <begin position="1385"/>
            <end position="1585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1615" mass="179662" checksum="3E7D76A52C683137" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DH65</accession>
    <name>A0AAD9DH65_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase</fullName>
            <ecNumber evidence="1">4.2.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_003362</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.-.-" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DH65"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04332">
        <property type="entry name" value="YbaK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.960.10">
        <property type="entry name" value="YbaK/aminoacyl-tRNA synthetase-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30411">
        <property type="entry name" value="CYTOPLASMIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30411:SF4">
        <property type="entry name" value="YBAK_AMINOACYL-TRNA SYNTHETASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55826">
        <property type="entry name" value="YbaK/ProRS associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1745438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="299" mass="33069" checksum="935C0A2E6613AA10" modified="2024-05-29" version="1" fragment="single">HKVSTYHPLSTALSTTTNLGRRTNYAVNSLSTPSNTIIRQNSATMASSSEDEAVQLLLSRIDAIEKSSWTTVANNNKQQKKQSNDEVNVNITPQMRRARRHVQTSHCYSSRWRLCPPDYYTLSLDERKVILGASCVSQLCKACLFENKNYKPTDGSAAAVDPTNSQYYLVVVQYVESIDMKKLASELRGLRPSGPKRLDPNYFSDMRLAPEDVSEKLTGFGHNGVSPFGMLDSTIPIIVCKNIVENVRPKFIWMGGGDKDWKLGMAVSECVSALNAIVLDVSEPRTLLQVGGTNCNTVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHP8</accession>
    <name>A0AAD9DHP8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6824 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003917</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHP8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049227">
        <property type="entry name" value="DUF6824"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20710">
        <property type="entry name" value="DUF6824"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6824" evidence="2">
        <location>
            <begin position="8"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="400"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="400"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="434" mass="46568" checksum="CDFBC0B52E313846" modified="2024-05-29" version="1">MTDPSPNDVLSGRGVSFNRHPGNENFRQLLDAQSNTYGAGTKKQKMAISKSIVERIYSMDPPGRFLKKCPNAGNWEELSMKEAATRTSQAMAYAVRERVKQGKERRSLRLKSNTVGAQSSQPAEDPPRLPSYVNISTVSASTARKSAETDRGGEGGSDADSFASNEDDGNKLGGNNEIPIPPANPSLQQQLLQLQQQSSTTAPLPANNAGVLNNSLVQLLAQAQLQQQQQQQHQQLLRQLVGQFPLGLQTQLPSASLSSTLSMSTPSLSAQGTLLPSINSDILRQASALPQGSTLMNSLQHSNLLQNQAQSQSSSLNTNSLLGLMGMLQNQPAPAPTITPQLPWLSQQLNQVQQNQLNQVQQNQLLASLLTTPNPNSLMLQQQSQPLNLLQQQATLLQQQMAQNTSNSASNSNPLTAANNAASTARGGGDDKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DI44</accession>
    <name>A0AAD9DI44_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">L-3-cyanoalanine synthase</fullName>
            <ecNumber evidence="3">4.4.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_003217</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>hydrogen cyanide + L-cysteine = 3-cyano-L-alanine + hydrogen sulfide + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17821"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18407"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:77860"/>
            <dbReference type="EC" id="4.4.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.9" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DI44"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050017">
        <property type="term" value="F:L-3-cyanoalanine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01561">
        <property type="entry name" value="CBS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000002">
        <property type="entry name" value="Cysteine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000006">
        <property type="entry name" value="Cysteine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005856">
        <property type="entry name" value="Cys_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050214">
        <property type="entry name" value="Cys_Synth/Cystath_Beta-Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01136">
        <property type="entry name" value="cysKM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10314">
        <property type="entry name" value="CYSTATHIONINE BETA-SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="6 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="11">
        <location>
            <begin position="42"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="220"/>
            <end position="224"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="10">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00050896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1746610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="392" mass="41778" checksum="6D63935CBE08219A" modified="2024-05-29" version="1">MLNIFTRSAASAAARSATSKLPSRIAITYQSSRHLNVASRPSDLIGNTPLIDLNKILVAHGVDVSNGVQLYGKLESLGPCSSVKDRLARSLIDDAEEKGLITPGESVLVEPTSGNTGIALAFIARERGYKCILTMPEQMSIERRMMLLALGAEVVLTPKETAVPGALAKAKEIVEGLDGKGIILQQFENEANAKIHRETTGPEVWRDTDGKIDMFFSGVGTGGTISGVAQYIKGSEEHNMPPLKPEMKAIAVEPMEQMLVTAALGGEKLGPQGPHKIQGMGAGLVPKVLDLNILDEVVPVHSDEAMAFANELWMCGLPVGVSSGAIVAAATKVCARPDSAGKLAVAVIPSFGERYFTHPMFSEIKEKAESLKKHALPPPFDNRDYGFATERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DI82</accession>
    <name>A0AAD9DI82_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000735</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DI82"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042095110" evidence="2">
        <location>
            <begin position="21"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="349" mass="39236" checksum="99BB8E9CF00DDB94" modified="2024-05-29" version="1">MLAYKTVSTIFLAWLCCVDALIVPSSVNYNRSSRSFSASLHATASKTTHRRKNKGSKQTNQISVTTQEPWLADYSTSVRSQKKIQSVPSKLRGKIQSCPSGTSCPKHFLNIPSSECNAANVVCALTTSAKTLSRGKHVNNKLNTTSEDLQTALMQTIDILNLLVTDKRLTARQLCNAAWAIAKHVEYDASLFSRDKYILVKDSSKSYSTWDLSQQQMSGDGTDKHIDDVLNLIALRMVEHLEQTRDRKYRIKTGKRAQPGELSMLLWAYAAAKPRDCPPGWEQPRRIEQLSDTQNTNSDNDFDVVTFVKTGRSFLRKVNIRQTILSTGVSLVDCLMRLQLRFAKEKVQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIK5</accession>
    <name>A0AAD9DIK5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002222</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIK5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051341">
        <property type="entry name" value="Zyg-11_UBL_adapter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12904">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12904:SF23">
        <property type="entry name" value="PROTEIN ZER-1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="673" mass="76995" checksum="0DA5C1C2CDF1A6D7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIZ3</accession>
    <name>A0AAD9DIZ3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sel1-like repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002612</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIZ3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="156" mass="17070" checksum="CB9739416BA5A445" modified="2024-05-29" version="1">MKRIEANDPVALCQMGGKLFHEGDYNTAFEYLSKAAGLGDFQAHFNLAVMYGVGQGVEEDEKKMIYHLEEAAIGGHPVARQKLGCIEGDRGEYARGLKHFIIAAKLGHDRSWEVVKESYAEGLVGKEDFASTLSAHQAAVDAMKSPQRQREAAEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJI0</accession>
    <name>A0AAD9DJI0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase</fullName>
            <ecNumber evidence="2">2.4.1.144</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001983</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.144" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1748020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJI0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003830">
        <property type="term" value="F:beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006813">
        <property type="entry name" value="Glyco_trans_17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12224:SF0">
        <property type="entry name" value="BETA-1,4-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12224">
        <property type="entry name" value="BETA-1,4-MANNOSYL-GLYCOPROTEIN BETA-1,4-N-ACETYLGLUCOSAMINYL-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04724">
        <property type="entry name" value="Glyco_transf_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="504"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="526" mass="60248" checksum="5B309B695A50DE18" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DKD1</accession>
    <name>A0AAD9DKD1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Solute carrier family 35 member B1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_000919</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DKD1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005459">
        <property type="term" value="F:UDP-galactose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005460">
        <property type="term" value="F:UDP-glucose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778:SF10">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08449">
        <property type="entry name" value="UAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="259"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="334"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="440"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1748980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="485" mass="52189" checksum="FD4AE160B41371FC" modified="2024-05-29" version="1">MRGLSYNHHNSPLKMKATPAPVVLTAGVGRNVKKPATNKNRKGKGGKQVHIRNNQNIAVDDDEEAGTSILLSATATTALHANGEGNNDNTILAVDSVEEMDRRRQQMIKRASVKLDDLYSAPPVIDTEVEAAKHKSSEFFWLAFCFFGIMGSFVCYGLLLEYATSGGKHLHELSFLFVTSLLYTLTASVGRYIRAEEQSTIPPAQFFVLGLTSMGSTFCSVRALRYVIYPIQVLAKSCKPVPVMLMGALMGKKYPAKKYVKVALIVAGVGLFMGGGDKSKKGADDDGKDASSQMIGVCLLFVSLCFDGGTGAYEDKLMSVHSVGPFDLMYNIQMGKTILAGIGLIVLNQVHIFVQMCQDMGFLLVALGLSGAIGQVFIFVTIAKFGALTCSIIGLARKVTTLVASIYFYGHHLNKVQSLGLVVCIGAMVNDFFGKKGKGGGHGHGGHGPSPQTDQFKDNCEENQPMLATVEEKDSALEMGTRSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-12-02" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6U3Z0C2</accession>
    <name>A0A6U3Z0C2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclin-dependent kinases regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_013351</name>
        <name evidence="5" type="ORF">SMAR0320_LOCUS21860</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the CKS family.</text>
    </comment>
    <dbReference type="EMBL" id="HBGZ01030701">
        <property type="protein sequence ID" value="CAD9628550.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6U3Z0C2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.170.10:FF:000003">
        <property type="entry name" value="Cyclin-dependent kinases regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.170.10">
        <property type="entry name" value="Cyclin-dependent kinase, regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000789">
        <property type="entry name" value="Cyclin-dep_kinase_reg-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036858">
        <property type="entry name" value="Cyclin-dep_kinase_reg-sub_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23415">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01111">
        <property type="entry name" value="CKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00296">
        <property type="entry name" value="CYCLINKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01084">
        <property type="entry name" value="CKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55637">
        <property type="entry name" value="Cell cycle regulatory proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00945">
        <property type="entry name" value="CKS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 4" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU311113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CAD9628550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1736215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="104" mass="12137" checksum="8391DE47EAD38194" modified="2020-12-02" version="1">MSGASRIEYSEKYADEENEYRHVILPKELAKTLPKTRLLSENEWRSIGVQQSRGWQHYAIHRPEPHILLFRRPLGTDPQTGAIDPELKRLALEEYKGQFGLRGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S0XNZ1</accession>
    <name>A0A7S0XNZ1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_010480</name>
        <name evidence="6" type="ORF">SMAR0319_LOCUS456</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">SM1012Hels-07</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="HBFJ01000616">
        <property type="protein sequence ID" value="CAD8733307.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S0XNZ1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006691">
        <property type="term" value="P:leukotriene metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.550">
        <property type="entry name" value="Membrane associated eicosanoid/glutathione metabolism-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050997">
        <property type="entry name" value="MAPEG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001129">
        <property type="entry name" value="Membr-assoc_MAPEG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10250:SF26">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10250">
        <property type="entry name" value="MICROSOMAL GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
        <property type="entry name" value="MAPEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="MAPEG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="112"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CAD8733307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1739164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="196" mass="21186" checksum="0527AFEDB28523F3" modified="2021-06-02" version="1">MTTKPLLICLSTASIGGFLELTTASKFTSSHHQSQLTAITPCILIGTGLWTLAHGFTVGKARIKYATLAKKDGETNVDERYLLPNLYAQGTSKHVRAFNCIQRSHQQIFETYTTVVLSGVMGAISFPICTAVSTFVYAVGRYQLSTGYAEAAEEGGDASKRYKYPLAKFMWYGFLCNVLLGMGSCGLIVGGKKTVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2P0S3</accession>
    <name>A0A7S2P0S3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">dTDP-D-glucose 4,6-dehydratase</fullName>
            <ecNumber evidence="6">4.2.1.46</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_005767</name>
        <name evidence="5" type="ORF">SMAR0320_LOCUS838</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="4.2.1.46" evidence="6"/>
    <dbReference type="EMBL" id="HBGZ01001149">
        <property type="protein sequence ID" value="CAD9571915.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S2P0S3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008460">
        <property type="term" value="F:dTDP-glucose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009225">
        <property type="term" value="P:nucleotide-sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05246">
        <property type="entry name" value="dTDP_GD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000304">
        <property type="entry name" value="UDP-glucose 4,6-dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005888">
        <property type="entry name" value="dTDP_Gluc_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43000">
        <property type="entry name" value="DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="4">
        <location>
            <begin position="20"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CAD9571915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1743146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="379" mass="42466" checksum="D42CF4D50FE65DFE" modified="2021-06-02" version="1">MVNSSFVPDEETDYIPKNILLTGGAGFIASHVAILLATKYPQYNVVVYDKLDYCSCLANLEEVSRLKNFKFVKGDICSPDLVSYVMTEEDIDTVMHFAAQTHVDNSFGNSFNFTQSNIYGTHVLLEAAKIHKGIKRFIHVSTDEVYGEGESFETDAMTEEHILEPTNPYAATKAGAEFLVKSYHRSFKLPCVITRGNNVYGPHQFPEKLIPKFTNQLLRGKPVTLHGDGSNTRNFLYVEDVARAFEIILHKATPGMILNIGGDNEISNLDVAKKLVELLGLKDKMDELITFVPDRKFNDLRYTINSSKLHQLGWTEQMSWEEGLDNTVEWYKKYTGRFGNIDDALVAHPRIGVAPGAAVTNIERSSSVYVKEFAAQGSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1H1W2</accession>
    <name>A0A8K1H1W2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS10c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">rps10</name>
        <name evidence="6" type="ORF">QTG54_017162</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="7"/>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2021" name="Front. Plant Sci." volume="0" first="0" last="0">
            <title>Chloroplast Genomes for Five Skeletonema Species: Comparative and Phylogenetic Analysis.</title>
            <authorList>
                <person name="Liu S."/>
                <person name="Xu Q."/>
                <person name="Liu K."/>
                <person name="Zhao Y."/>
                <person name="Chen N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CNS00100</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the binding of tRNA to the ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Plastid</location>
            <location evidence="4">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MW679506">
        <property type="protein sequence ID" value="UAM91370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_010200875.1">
        <property type="nucleotide sequence ID" value="NC_058701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1H1W2"/>
    <dbReference type="GeneID" id="68637994"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.600:FF:000003">
        <property type="entry name" value="30S ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="entry name" value="Ribosomal protein S10 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_uS10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_uS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_uS10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_uS10_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001861">
        <property type="entry name" value="PRK00596.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01049">
        <property type="entry name" value="rpsJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S10 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00971">
        <property type="entry name" value="RIBOSOMALS10"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="Ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS10" evidence="5">
        <location>
            <begin position="10"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1732119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UAM91370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="107" mass="12422" checksum="886AF3D0DB387EE8" modified="2022-08-03" version="1">MEIKPNEKIRVRLESFNHELLNTSCQKIMEITQGNNIDNVGVVSLPTDKRIYCVLRSPHVNKDSREHFEIRTHKRILEISYDSSVNIFDLLVKSDLPPGVLYRICLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRQ3</accession>
    <name>A0AAD8XRQ3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016943</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000069">
        <property type="protein sequence ID" value="KAK1732364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRQ3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="entry name" value="Intergrase catalytic core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="572"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="725"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="743"/>
            <end position="752"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="771" mass="87569" checksum="1C9B57EFD76E6D49" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRR7</accession>
    <name>A0AAD8XRR7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016989</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000073">
        <property type="protein sequence ID" value="KAK1732322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRR7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="304"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="395"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="658" mass="74455" checksum="675A20EADDF86486" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRW6</accession>
    <name>A0AAD8XRW6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_017055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000077">
        <property type="protein sequence ID" value="KAK1732280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRW6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="338" mass="36029" checksum="28F245A72FA698D2" modified="2024-05-29" version="1">MTAIKIKAASKSTNAPPADEAAPKSPTASISSGDDAAPPASSSNANDRDNDSSIDDGSSNGGSFSGNEEAVVDGEVKASSVKGGEGEEDATGEEEDANHDSNDAAGEEGNVETAATDSAKEEEEEKGNDDEKEAEDAHAANATSGNEGQDEDAIDAEEKEEDGNEGEEEWELKKILSVGEISAKNLMCSAPSCPNVACSVYQSTHDTNCTNAYFSCLDCQQSDYGGWPEDKSEIPMAFMTKQHRDTIRQHCTRNPANAVFPELPTSRNGEEEEKSDDEEAGEGEEKWDLIEVIAVKDLKKKKPKKCQEEGCTSAACSVWASNLAPDDEWYGCIDCMEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRZ6</accession>
    <name>A0AAD8XRZ6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Tim23 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_017001</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000074">
        <property type="protein sequence ID" value="KAK1732301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRZ6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045238">
        <property type="entry name" value="Tim23-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15371:SF0">
        <property type="entry name" value="SD19278P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15371">
        <property type="entry name" value="TIM23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1732301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="219" mass="22585" checksum="5582A34D40F53F27" modified="2024-05-29" version="1">MSNNNLGSGRGGASPYDDDTSSTTSSAGSPIPDFNASNIQLSTVAPAFGISSSAAAASGLQTRQPDYLDYDQKGRGIFSIMCTNSGISYLVGVTIGGLYGLKEGLARTPSSRWKVKLNSVLNHCGRHGSGLGNMMGASAIMYSLYEGVADSFELDAYTGPIQPPAPLFAGMMTGATYYMRAGPRVAALAGTIGLGAVGGTFALYSVLGIPYGSKGWLFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSX0</accession>
    <name>A0AAD8XSX0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_016181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000054">
        <property type="protein sequence ID" value="KAK1733043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSX0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="393" mass="44788" checksum="531B450650781912" modified="2024-05-29" version="1">MMPLEVTEIAAIVSLLICDICPSFTRVNRLLPDNRTIEMTWVENDDDHFGFDMDRFWPTDCTLSPHEKLALYWKYTRSTGCNHFSAILAKVLKGLCDNGELLVHNGMPVVDIFALNSMEFDVSDILSSSDQLLKIHDPVSDVTVPCISTHQQMEKLLNMGEKACHRLGLELPEKVSKEWNMMKKYVPDSYKTTVPHWWLAVVVEGQDTSHSEKQHTMVHLDVCGAAYDESALSKVPGNDSLVSLKVFSTPEYELRPHMAPGLSHKLVMLPTLRPSTDRQRGIISHQPKSLRYFRCYHAKRPSPEISPAAIEVTPLQTFLKRNEFDDAKNVIIDELVETLQQPLSLKNLRVGTKVLTRNTHSHIISYASIQTRTMIVEVIVRRDKRCTLSFQYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XT94</accession>
    <name>A0AAD8XT94_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mpv17/PMP22 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_016151</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000053">
        <property type="protein sequence ID" value="KAK1733174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XT94"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF80">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042163231" evidence="8">
        <location>
            <begin position="27"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="50"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1733174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="271" mass="29656" checksum="04E1FE255A9E7E2D" modified="2024-05-29" version="1">MKTIASSSNTLLLVLSSCGVGSLTNAFMSPQQSTYTPLSYQRNTPLAHLPSPSNDAQPQSSSSSSTCLHLAELSGGITEVWNSYLDALEANPLLVKSITAGVILGAADLSGQALQQAIATNNDDNMELSTNNNNSNSVDIARFLRFAFFGFILQAPWNHFYYQILDGALPPTEDPFTSTTAIKVVIDQFIQAPIFTVIIFGFLGVLEGKSLDSIKEQLDEDYVDTMLANWKLWVPATAVNIAFCPPILRVLFLNVVFFFWSIFLSLKLNKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUJ9</accession>
    <name>A0AAD8XUJ9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sel1-like repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_015664</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000046">
        <property type="protein sequence ID" value="KAK1733621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUJ9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF147">
        <property type="entry name" value="SEL1L ADAPTOR SUBUNIT OF ERAD E3 UBIQUITIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="359"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="671"/>
            <end position="712"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1733621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="768" mass="86167" checksum="3736BFD8312BAC94" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUM6</accession>
    <name>A0AAD8XUM6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA pseudouridine synthase</fullName>
            <ecNumber evidence="4">5.4.99.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_015202</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUM6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050343">
        <property type="entry name" value="RsuA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47683">
        <property type="entry name" value="PSEUDOURIDINE SYNTHASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47683:SF2">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="3">
        <location>
            <begin position="90"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1734199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="387" mass="43524" checksum="A0DD047406B25A9A" modified="2024-05-29" version="1">MPPKNAPRFLDYRQRKLPLDVALSFALPPTIGDNCSARDLILSGRVLVNNITERSCNRLVDRFDDAISIIESEDDTSATMTISFITKPRYYICYKPRGVVCSRRRNEGIDREDSVLISDWLARVFEAAENIIGEDNNNATIKTVGRLDEESEGMLLLTNDGSFSRLLCDPEFGLMKTYRVVVRGSGYNKLITDTVEQSDIQNIGNTNEDCAANEKEVTHELMKKRVSERIESANDTPTVTTDINGKQTMHHFPFETCNVLDVGKLPSQHSSDDSYYALIDLILCEGKRHAVRRICKNAQLRVCYLSRISVEGLNGQYDVVKPESIAEAHSNGFIPGGRHRDVVLNGKLITRSDHKDMSLLHSGHVVELRDCDVDRIFALRTQQELGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUN4</accession>
    <name>A0AAD8XUN4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015575</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000045">
        <property type="protein sequence ID" value="KAK1733720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUN4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAP" evidence="2">
        <location>
            <begin position="80"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="462" mass="52018" checksum="EFECCA1AB77D3D38" modified="2024-05-29" version="1">MQGGQHYAKYFLFEVTHMGILAKAFSQLIYHQSPSPAGNSAAHQAIEPRQDAPLEHHSPPVTQAEPQEEAVNNDWTEASLKALKNDELKAILQGLGLKRSGNKKELVDRILGREVVTENKEKPKWRNSKARAMLVRMLMDKQSNVHKMTWKEIHASHEWFQEYDPMLFHDMRAFWDTHPAKLLLRGDVKAGKHLDMKPALLHQTRSEYKAFSLKTFRAHVYQEKRHQKELPMRDNEDDESVEVWEEFCHDDVSEDGDEEDQIMSPKKAFLVKVNQKADADGPWGDEADAQAAADTQIITVVIWDTSNIQNGPEVYEPAGMEEEDMTDDLQVILVKHDQMFYRVVLANDDGTDDDDDGLDLRVRTNLDALLDENAPTTPSSRARDAINAVSAVVSGAVSSAYAPSPPAAALLPIATVERERGGAVRTQIALQFQIMPTTSQRLSSSLHYFMCKSFVFGESDGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV08</accession>
    <name>A0AAD8XV08_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cyclin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015465</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV08"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000093">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="2">
        <location>
            <begin position="77"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="449"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="479" mass="53548" checksum="F0DB9AE7647CDFB8" modified="2024-05-29" version="1">MNTMLVSPHFDEVEPMQEIEVISSGGYDNITTTCSSTSSPIISSVMTFPPRADSAETIEKNRQKSEDAMQALLAMVEKERTIPPIDYDHNSPAGNAVNNIDRQKMCEWYYEMADFLKIDRSTASRSMMLLDRFMAASTHSHVAAAARQNRDQYQLFALTSLFITIKLFERLNIQAEHVSYLSRGRYGPQEIIKMEIVMLAALQWKVSEASKVDYVDIIMNYIIPRMENCSYVMRSSELLEKIKELALLQIQLSDFEASFSSRRQSIVAFAAVCNAFETKKAGMSQSNKEAFYDCIKSVMRIMSLSDSSGRDELGSTIQELRFTVDPQAAAMSDDATTNAIYREHDAPSHTTEDVEDFASSPIDCALESMESFSMSSFLCCGASTPITQPPKELTVVRNSSSSSSSSDDDCNDDHHNRCNAFDNFSLTNCYSFDSSTSFESVDLKSNNKKGTFKPISSKKKKESTTSRSPTSIAMMLRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV34</accession>
    <name>A0AAD8XV34_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_015218</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1733960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV34"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097272">
        <property type="term" value="P:ammonium homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3430.10:FF:000016">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11730">
        <property type="entry name" value="AMMONIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11730:SF6">
        <property type="entry name" value="AMMONIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111352">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="279"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="339"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="421"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="10">
        <location>
            <begin position="46"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="488"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1733960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="539" mass="58090" checksum="AA9756BE561D75E2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVL7</accession>
    <name>A0AAD8XVL7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014567</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVL7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="103"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="696" mass="76459" checksum="6198EF055668BE81" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVS0</accession>
    <name>A0AAD8XVS0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVS0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="175" mass="20226" checksum="7D564B279AA76923" modified="2024-05-29" version="1">MSALPDNVKAVISRLSVQDQVVIRSYIAGMRDELKELKVKLEHADDDDDPHAHYHGHEKCTADHGHQDHEHKEDHHSHEHHGEKKCTEDHSHDHKHDDHKCDGGHAHEHKHSSHDHTHNHHKKEEHDHHEHAHKHHEEKEDEDMPAWKKQAIDADPNAAPFGGSWNVESSMDATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVX9</accession>
    <name>A0AAD8XVX9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Spermidine/spermine synthase family protein</fullName>
            <ecNumber evidence="5">2.5.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_015078</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000040">
        <property type="protein sequence ID" value="KAK1734311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVX9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010487">
        <property type="term" value="F:thermospermine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006596">
        <property type="term" value="P:polyamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003582">
        <property type="entry name" value="ShKT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43317">
        <property type="entry name" value="THERMOSPERMINE SYNTHASE ACAULIS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43317:SF1">
        <property type="entry name" value="THERMOSPERMINE SYNTHASE ACAULIS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01549">
        <property type="entry name" value="ShK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01564">
        <property type="entry name" value="Spermine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00254">
        <property type="entry name" value="ShKT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51670">
        <property type="entry name" value="SHKT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041979526" evidence="3">
        <location>
            <begin position="26"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="domain" description="ShKT" evidence="4">
        <location>
            <begin position="955"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="49"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1734311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="998" mass="110055" checksum="B272E3B51F8CFB2E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW14</accession>
    <name>A0AAD8XW14_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XW14"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="382" mass="42686" checksum="4ABB83B9190CDED1" modified="2024-05-29" version="1">MNGKTYAVAEGRWWLMKNPIKAHWFKDAKNQTLDDDFITVGQVRIVRVLPGEVGLIREQGTEVLLDVGTHVFNSGIVSVQGKVKYDELKNFNHGRYHYLRVDRGYFARVWAVVMTDGMETVVPRLLGQGTHYIANHMFKFDGFSKVSDPVIAHGSIHKVNVVKGKIAKCVQDTTSRLLGEGEHTIESTDFQVVGFEDIMKSHCIQHGTITTKGKVALAWKDNDPIFITEPGLYEFDSADFSFDSFRDAEERLIQLGAKKIVQVQTGRVGVTYDNGVLKVLRNGTHEIDSATHIVHRFLSIQEKSIRLATLSGNEKLARSMKRSQAGKQSDASAKPNKPKQGVSDLIVDDKDADLTICETKDLVKVGIRADVFFQSPIQRNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW19</accession>
    <name>A0AAD8XW19_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014517</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XW19"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="459" mass="53139" checksum="10B08343BF16F957" modified="2024-05-29" version="1">MKPTTIPITGRRSMYRGFANTTSSDVDVELNETDIDSRATHLLEEIHRVRRNYGENDLVESNVLQQVEQTFEAEDYLRALESEVDRLLRSQAMTKRHRSSTGDVNYLESQNDTHCRACNSSPCKWSPHCDVDALAKRRKALFGEIKSVDDRRKRQISEEIQVISAKLKLTLVDKELHEAYAANDNETITVRSIHGFPATLNRVDAIAALEHEHNRHVGSIVAKKVVDDVLIWMLDGWYFGQYSKPSSSLSNPPPSFVKRGSLLEKANDIQMHSNAAALNSLALHEEKKAKLASMQTTTKYALFCITFSYFRALHLVRQQKEAFSLSRSKPPLSNERIKMIQEHKNCVGRQQRLEYYMRKARVGEERKLQRIEQERLEKRRISQFEDMNRLAMNRLAAIVQRVYRGYLGRKSVENLRLERQKAALALVFLNDCATEIERAWRGYCGRRDAERLRREMAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW70</accession>
    <name>A0AAD8XW70_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014454</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XW70"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="94" mass="10465" checksum="486BA53DF0965395" modified="2024-05-29" version="1">MQAHSPIATVLHTNFSYCNRIVLSTLFISLLLASSCCWCRMPTEWACLLQPRLYLTHLIGIITASADHLLQHDFITDFDGSSGCGKKQIGQSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XX40</accession>
    <name>A0AAD8XX40_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">U3 small nucleolar RNA-associated protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_014280</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XX40"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000378">
        <property type="entry name" value="U3 small nucleolar RNA-associated protein 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012952">
        <property type="entry name" value="BING4_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040315">
        <property type="entry name" value="WDR46/Utp7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14085:SF3">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14085">
        <property type="entry name" value="WD-REPEAT PROTEIN BING4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08149">
        <property type="entry name" value="BING4CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01033">
        <property type="entry name" value="BING4CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="337"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="BING4 C-terminal" evidence="8">
        <location>
            <begin position="420"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="575"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="575"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1735214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="609" mass="69155" checksum="BE493476C70F1DCB" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXA4</accession>
    <name>A0AAD8XXA4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2039 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXA4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019351">
        <property type="entry name" value="DUF2039"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22876:SF5">
        <property type="entry name" value="CHROMOSOME 9 OPEN READING FRAME 85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22876">
        <property type="entry name" value="ZGC:101016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10217">
        <property type="entry name" value="DUF2039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="300" mass="33558" checksum="2E1F9E788168E3D5" modified="2024-05-29" version="1" fragment="single">MPQRTTPGGSKKKKGRAPKHQNSFAFRHNPKSKKTDKILNSPNVGVCRRCHDKIEWRKKYRKYKPRTQLGKCNLCCGKNIKAAYHTICTECAGGDRAIADMEKRRGGGGVVVVQPAGEKDVESPTTDGEEPTSTDDNDATSNPVDQTAIRRARRRLRVCAMCASEPALSKHSYGDGEDEDLIEDIHLLEDKIEDGVNDEGKKLTLREIKSLERKIEKLQLEMKERRKARENKDDEEEEEEGNEDDGSDGGDGEETDSVQLGDVTEEQDNDDDANDPFLQAIGGKDKLLVGEEYQKMLLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXQ1</accession>
    <name>A0AAD8XXQ1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Serine/threonine-protein kinase</fullName>
            <ecNumber evidence="9">2.7.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_014292</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXQ1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000624">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="4"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="301"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="392"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="301"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="315"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="392"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="423"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1735226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="523" mass="59340" checksum="F5FF0E160D76855B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXZ2</accession>
    <name>A0AAD8XXZ2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">REJ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1735954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXZ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042255997" description="REJ domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="236"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="251" mass="25318" checksum="0171BD66E280E34F" modified="2024-05-29" version="1">MKLLHILLISLIASAAASTSSKSSKTSSPTYTPTEYSKSSKSSSRRELSSSKSSKSTSSPTYTPTEYSKSSKSSSRRELSSSKSSKSTSSPTYTPTEYSKSSKASASASASAKSSKSGGRKLESSSTKSSKSTTSSPTYSTKSAKSSDPSSSTKSAKATTSSADSSVSKASKASTKSTKASASDPSSTAKSSKSEPSPSSAKSAKSAYPSGTGDDVSSSSKSGKSGSSSSEDDDNISSSSKSGKSGYDDGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XY64</accession>
    <name>A0AAD8XY64_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013766</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XY64"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="178" mass="18300" checksum="586A886BE207AE52" modified="2024-05-29" version="1">MALTGDVYANEDSSSEEEAAVMENNPSAEAEILAAAADDDNDGNIKENIKFTASRLKEHDEQMDSDSTSQQNTEEKDAAVSSAGAGLLFGLSGLILGGPVLGTIAGVSAAVVASNDQGPAGDNARAAGTFAITTGSKVGDAARDVNEKHGILDWIQNVLSSGWGKFGNLTTSITLQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZA3</accession>
    <name>A0AAD8XZA3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UbiE family methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012708</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZA3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43036:SF2">
        <property type="entry name" value="OS04G0481300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43036">
        <property type="entry name" value="OSJNBB0011N17.9 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042125706" evidence="1">
        <location>
            <begin position="23"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase type 11" evidence="2">
        <location>
            <begin position="214"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="327" mass="36687" checksum="C51B654AA0E7F5EE" modified="2024-05-29" version="1">MKIGYWLAAAVAAACCAPPSCALSFSRAKSITRSNFIQSTASAIFFSDIVASTPACAADKDKMQQNPRYIENEVQMKYGDDSKGNPRTRGVLVRRFTGDSTPYSFKTSPVSLVKEWPESPPFTQKDFFRADEGDDENFYTLPRLVYHIDEPAVASLTQYYRANIKPGSSILDICSSWVSHYPLEFKDNMKRISATGMNPLELMANDQLTDYEARNLNINPALPYEDNSFDVVTCVVSIDYLIKPIESLKEVHRVLKPGGKVIISQSNRCFPSKAISMWLNMNDRQHLELINGYLQYAGFGKAQAYDITASVPGERFNDPMFIVEVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZP3</accession>
    <name>A0AAD8XZP3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_012846</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZP3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041987062" description="Transmembrane protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1736246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="136" mass="14284" checksum="A36ED8201563B25C" modified="2024-05-29" version="1">MRLLLLTALLQALLLSTSNAFTSPSTTTARKSINSKTTLSPLYNTEDSSSDDDSSSSTLTLEEKMKSWEASDEEIRAATLGGVIPGGGGGGERTDGFDIGLYIAFPFMVIGCLIFAFFPLIVGNIDVTSVGPPPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZV1</accession>
    <name>A0AAD8XZV1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">RING-type E3 ubiquitin-protein ligase</fullName>
            <ecNumber evidence="9">2.3.2.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_012955</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZV1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16464">
        <property type="entry name" value="RING-H2_Pirh2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039512">
        <property type="entry name" value="RCHY1_zinc-ribbon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008913">
        <property type="entry name" value="Znf_CHY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037274">
        <property type="entry name" value="Znf_CHY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017921">
        <property type="entry name" value="Znf_CTCHY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21319">
        <property type="entry name" value="RING FINGER AND CHY ZINC FINGER DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21319:SF53">
        <property type="entry name" value="RING FINGER AND CHY ZINC FINGER DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14599">
        <property type="entry name" value="zinc_ribbon_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161219">
        <property type="entry name" value="CHY zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51266">
        <property type="entry name" value="ZF_CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51270">
        <property type="entry name" value="ZF_CTCHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CHY-type" evidence="7">
        <location>
            <begin position="197"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="CTCHY-type" evidence="8">
        <location>
            <begin position="328"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="378"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="120"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="517"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="120"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="169"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="536"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="558"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1736355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="569" mass="62631" checksum="F5AD7737D9CBEBA7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y018</accession>
    <name>A0AAD8Y018_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012509</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1737064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y018"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026894">
        <property type="entry name" value="DnaJ_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052423">
        <property type="entry name" value="EMIR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44094">
        <property type="entry name" value="DNAJ HEAT SHOCK N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44094:SF8">
        <property type="entry name" value="DNAJ HEAT SHOCK N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14308">
        <property type="entry name" value="DnaJ-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="199"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="591"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="603"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="635" mass="68959" checksum="C54F02ABB1054DB1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0B3</accession>
    <name>A0AAD8Y0B3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Hedgehog protein Hint domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012078</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0B3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016540">
        <property type="term" value="P:protein autoprocessing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00081">
        <property type="entry name" value="Hint"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.16.10">
        <property type="entry name" value="Hedgehog/Intein (Hint) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001767">
        <property type="entry name" value="Hedgehog_Hint"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01079">
        <property type="entry name" value="Hint"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="Hedgehog/intein (Hint) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="Hedgehog protein Hint" evidence="2">
        <location>
            <begin position="146"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="608" mass="67737" checksum="5FA12F14CAA8EE9F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0J7</accession>
    <name>A0AAD8Y0J7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0J7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01228">
        <property type="entry name" value="EGGSHELL"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042109118" evidence="1">
        <location>
            <begin position="18"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="311" mass="31666" checksum="193C3250FB75627C" modified="2024-05-29" version="1">MKTTIALLLSLIVATSAFTNSPIGKAMPRLGITTETTQPADVAASTCPARNTESVVLNNMLRSYANWNDVWDGDYGYGGYGGMGGGGGGGMMGPYRGGYRRGGGMGGGYGGGYGGGYGGGYGTGLALRRDVPSRDVSSTPVLSGSDVWRDDWSFPMTSYNRGYGRSSSNNRRYGRGGGYGMGGYGDYGMMGGYGGGYGMGGYGGGYGGYGGGMGGYGGYGGGMGGYGGYGGGYGGYGGGVSSQRYGGYGRGGYGGGGSGGYGLGYSNMNNFPETRERGARRRYSRDYYPNYGYGGYGGGGYGGYYGRGGYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1S2</accession>
    <name>A0AAD8Y1S2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Glutamyl-tRNA reductase</fullName>
            <ecNumber evidence="3 8">1.2.1.70</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_011738</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>(S)-4-amino-5-oxopentanoate + tRNA(Glu) + NADP(+) = L-glutamyl-tRNA(Glu) + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12344"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57501"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="EC" id="1.2.1.70"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glutamyl-tRNA reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.70" evidence="3 8"/>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1S2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008883">
        <property type="term" value="F:glutamyl-tRNA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05213">
        <property type="entry name" value="NAD_bind_Glutamyl_tRNA_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.460.30:FF:000001">
        <property type="entry name" value="Glutamyl-tRNA reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.30">
        <property type="entry name" value="Glutamyl-tRNA reductase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00087">
        <property type="entry name" value="Glu_tRNA_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000343">
        <property type="entry name" value="4pyrrol_synth_GluRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015896">
        <property type="entry name" value="4pyrrol_synth_GluRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015895">
        <property type="entry name" value="4pyrrol_synth_GluRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018214">
        <property type="entry name" value="GluRdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036453">
        <property type="entry name" value="GluRdtase_dimer_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036343">
        <property type="entry name" value="GluRdtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006151">
        <property type="entry name" value="Shikm_DH/Glu-tRNA_Rdtase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01035">
        <property type="entry name" value="hemA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43120">
        <property type="entry name" value="GLUTAMYL-TRNA REDUCTASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43120:SF1">
        <property type="entry name" value="GLUTAMYL-TRNA REDUCTASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00745">
        <property type="entry name" value="GlutR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05201">
        <property type="entry name" value="GlutR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01488">
        <property type="entry name" value="Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69742">
        <property type="entry name" value="Glutamyl tRNA-reductase catalytic, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69075">
        <property type="entry name" value="Glutamyl tRNA-reductase dimerization domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00747">
        <property type="entry name" value="GLUTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0521">NADP</keyword>
    <keyword evidence="5 8 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 8" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042092717" description="Glutamyl-tRNA reductase" evidence="10">
        <location>
            <begin position="22"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamyl-tRNA reductase N-terminal" evidence="13">
        <location>
            <begin position="97"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase" evidence="12">
        <location>
            <begin position="277"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation" evidence="11">
        <location>
            <begin position="419"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF05201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1737452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="535" mass="58543" checksum="6300F125E4CE3C57" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1W0</accession>
    <name>A0AAD8Y1W0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1W0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="219" mass="25287" checksum="BAF0E1146570C6FF" modified="2024-05-29" version="1">MHVGIEKIEEDAFYGCTSLRKINLKGVREIEADAFYSCRALADVEFGTKLDRIGQEAFGNCKSLQKIKMPSVRTVDPMVFINCAALTDAEFGCNLETIEQRAFYLCPNLRRIAVPLKDDIFPASGNMISLHPTRQYMWYNQFDSCENLTTVDLVGVERIHKTISSLLLESWRTEMIAEINRINQMLPINVPSTKADTIRWWIMRVIDRMEHFKAEHIDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y266</accession>
    <name>A0AAD8Y266_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_010915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y266"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1738246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="558" mass="63999" checksum="6239C0A5B79B5616" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y285</accession>
    <name>A0AAD8Y285_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycosyltransferase 61 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_011792</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y285"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049625">
        <property type="entry name" value="Glyco_transf_61_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007657">
        <property type="entry name" value="Glycosyltransferase_61"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961:SF124">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase 61 catalytic" evidence="4">
        <location>
            <begin position="315"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1737506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="549" mass="61070" checksum="227E8F767E0F738F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3A2</accession>
    <name>A0AAD8Y3A2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Vps72/YL1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011063</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3A2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013272">
        <property type="entry name" value="Vps72/YL1_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08265">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00993">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vps72/YL1 C-terminal" evidence="2">
        <location>
            <begin position="175"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="233" mass="25366" checksum="FD175E3D1AB66F09" modified="2024-05-29" version="1">MSTAAQRKAWNEAMREAGAKVPSSGSAGRASDRRRKASRRDKARKSSVYGGEAGGSTLEEREFRVAIHMDMLEGVTDNAAAGVDDDDDYDEFADLDDEGDKGKKGTKKKRQRKSAAKSKKASSSANYLRARSLASILIEEANRSDSTAKQYVAAAVHQYDNSNSGAITPYPPARKYCPVTGLFGVYTEPKSQIPYANLKALEQIRERAPPWMNTSSSGSATYLEAIKTLRNDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3C3</accession>
    <name>A0AAD8Y3C3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Papain family cysteine protease</fullName>
            <ecNumber evidence="8">3.4.22.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_011310</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.22.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3C3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02248">
        <property type="entry name" value="Peptidase_C1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000332">
        <property type="entry name" value="Cathepsin L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013128">
        <property type="entry name" value="Peptidase_C1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000668">
        <property type="entry name" value="Peptidase_C1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039417">
        <property type="entry name" value="Peptidase_C1A_papain-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013201">
        <property type="entry name" value="Prot_inhib_I29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12411">
        <property type="entry name" value="CYSTEINE PROTEASE FAMILY C1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08246">
        <property type="entry name" value="Inhibitor_I29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00112">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00705">
        <property type="entry name" value="PAPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00848">
        <property type="entry name" value="Inhibitor_I29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00645">
        <property type="entry name" value="Pept_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041960034" evidence="5">
        <location>
            <begin position="20"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="Cathepsin propeptide inhibitor" evidence="7">
        <location>
            <begin position="54"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C1A papain C-terminal" evidence="6">
        <location>
            <begin position="172"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="133"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="151"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1738016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="407" mass="44853" checksum="F0458DC577F853CA" modified="2024-05-29" version="1">MMAALKLSTILLAIVLAVANGDATLNAARHFLDSTPPKVVVSSTYPSTEVHSKFQQWKEKFDREYESIKEEALRKLIWIENHAHIETHNDQLPTPSYTLGHNDFSDITNDEFKQRFFLGEYSPGIFEAKGRSDGSIFPLTSQQRKLRGPEDDVLQDDTEDDDDSDTQPVEDVPESKDWNDEGAVSPVKNQWFCGSCWAFSAVGAIEGARAIATGNLTELSVQQLIDCDTTDLGCGGGLMNNAFQYDEDSGGLCSYEAYPYALHQHWFSGCARYLPYCTPVPHSTVSKFVNVTETEDDLKAAIATQPVSVAVSAGTSAWQFYRNGVFSGGCDDEIDHGVLAVAYGHYDPDPVHMNATAMDYFTIKNSWGTMWGEQGFIKLGRGVGNEAEGGSSCVLKFASRPIMKKDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3J3</accession>
    <name>A0AAD8Y3J3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycogenin</fullName>
            <ecNumber evidence="3">2.4.1.186</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011415</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.186" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3J3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008466">
        <property type="term" value="F:glycogenin glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050587">
        <property type="entry name" value="GNT1/Glycosyltrans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11183">
        <property type="entry name" value="GLYCOGENIN SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="785" mass="86573" checksum="1AAFA2427E114DE0" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3Z1</accession>
    <name>A0AAD8Y3Z1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Leucine-rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_010664</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3Z1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1738634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="187" mass="21435" checksum="00CDFB48F6C5D444" modified="2024-05-29" version="1" fragment="single">MADNADDADGADVFMYRGGRAPRNVTHVVIDKSVEVIEDEAFELCENLVQVETHDGIRSVGRMAFWRCKSLRRINLRSAVEIGKSAFCRCVNLVSVEFGETVEIGLMAFWGCENLERLNFTSIIIIGTDSFSYCEALTDIEFSERLETIEAGAFRECKRLQRIAIPLKRDLFVYDDESEQYKQFYRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4P8</accession>
    <name>A0AAD8Y4P8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Strawberry notch family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_010444</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SBNO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026937">
        <property type="entry name" value="SBNO_Helicase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026741">
        <property type="entry name" value="SNO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039187">
        <property type="entry name" value="SNO_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047365">
        <property type="entry name" value="Tudor_AtPTM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12706:SF30">
        <property type="entry name" value="PROTEIN STRAWBERRY NOTCH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12706">
        <property type="entry name" value="STRAWBERRY NOTCH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13872">
        <property type="entry name" value="AAA_34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13871">
        <property type="entry name" value="Helicase_C_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21743">
        <property type="entry name" value="PTM_DIR17_Tudor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="7">
        <location>
            <begin position="118"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="74"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="841"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1621"/>
            <end position="1651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="92"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="841"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="899"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="928"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1638"/>
            <end position="1648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1739128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1835" mass="203950" checksum="FDA3AFB07FB454E8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6T1</accession>
    <name>A0AAD8Y6T1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-CH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_009024</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6T1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-CH-type" evidence="4">
        <location>
            <begin position="13"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1740074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="435" mass="48836" checksum="0B57B434A63D41E4" modified="2024-05-29" version="1">MSSASQSTSVVSITPPDGASCWLCLEEGPDDSGAPLVRDCSCRGHSGFAHLPCLIQYAESKSRDLAERGALTLREFFQEKIFEQCPNCKQTFQGNIPYGMTTAQLAFFEREFKDVQSWQMGALMKRIHVLDGRKDVDRIEGEEICTKMLSLIDEMKKNSDPSLDVLALATIYQEIGIFYYRVDTKQSLKKGKRCLEISRDIVITFGGRELQCLVEAIKNNLANVEARLSGVSIPNEKESDLSSIRARYNCLLQAVGQNDIRTIEMGTLLASKLFNAYHTIEASRLLDRLVIISCRVHGSDHKQTKIAESWRQRLQLRCAFIGSEQQPYQALRYEDDGDSCIVQGPVPKNVPRNDDDCQTFSVPSVEISFSLGTPVMLHGLKKAAHLNGEIGDVREYCKLSGRCVVHLEDKDLKPVKVKHENLRIVFDLPDPKNLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y718</accession>
    <name>A0AAD8Y718_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y718"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042003196" evidence="1">
        <location>
            <begin position="21"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="192" mass="20458" checksum="B9160C9A90E43C26" modified="2024-05-29" version="1">MNLITSILLVFLAAAAIAEANGNRQLGSKGGKASYSYSSKGGKASYSYSSKGGKASYSYPMSMGKSGKGSKSSSKGGKGSKGGKGYSYSMSYPGPDFCDNLRFSECVIYIVEVIETSGVLLFQQQTMSGSPLGEDQDTEQEARDIVEDNRGYVLAGAAQQEIYSRCWTGSGELVDDPVYFPDEPDCRTITLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7F8</accession>
    <name>A0AAD8Y7F8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helicase-associated domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7F8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.530">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005114">
        <property type="entry name" value="Helicase_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33418">
        <property type="entry name" value="HELICASE-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33418:SF1">
        <property type="entry name" value="HELICASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03457">
        <property type="entry name" value="HA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase-associated" evidence="2">
        <location>
            <begin position="468"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase-associated" evidence="2">
        <location>
            <begin position="541"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="205"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="440"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="454"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="615" mass="68514" checksum="75AA877112A76CF5" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7R8</accession>
    <name>A0AAD8Y7R8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008715</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7R8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="412" mass="46351" checksum="0DDF665A0DDCF4C0" modified="2024-05-29" version="1">MLPNSDSRYRKDGGSNNANRNKVLFCCAALALSLTSIKLSGTTRFLGISNAAAEDDLIKAETFSFDLTDEENDITDTTPLFDSSFAEYLKKGLSWYVANAGNKHFFYPDSNFHKTWPKADIPYWTKKRFPLNKYITPGKQTCFMHVGKAGGSTIGCLLGFSLHCDTNNQTVTSLLAATTAHATHRCVHDCSDEAAYHLFVVRDPLARALSAFNYGKQKLLEKNSTSKGWVRDKELIFDCEFSSLNDLAERGLVKDSHNATEECRVGAKNALLGTETSLIHWYYNYQYYYEMVSPDANIVVIRNEHIVDDWNAVETLLGGDADFTQEHVPVNNAREKKPEEVYLSDAAKVVLCETLCNEIQVYKTILKRAQNIKNEHYVQSMQELVTSCPKEAMEESCPDAKPDIREKVDGCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7U7</accession>
    <name>A0AAD8Y7U7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Phosphatidylinositol-4-phosphate 5-kinase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_009306</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7U7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.110.10:FF:000002">
        <property type="entry name" value="Phosphatidylinositol 4-phosphate 5-kinase 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23084:SF263">
        <property type="entry name" value="MORN REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23084">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="399"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1740356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="519" mass="58939" checksum="87C042142128E974" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7Y4</accession>
    <name>A0AAD8Y7Y4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007952</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7Y4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050789">
        <property type="entry name" value="Diverse_Enzym_Activities"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042227131" evidence="1">
        <location>
            <begin position="20"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-related" evidence="2">
        <location>
            <begin position="54"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="220" mass="23381" checksum="9FB8ABD3E0E17C4E" modified="2024-05-29" version="1">MKNLLFLSSATALFSSTSASGVDSATWEQDLVTAWESIGDCSPSTGICSQCGLGVAVVDLNGPNGLETRVYNAGPGDREAPWGPDNHWEIASVTKPFTAVAMLVLEDEGILTRDTTIGELLPCDWEKANSDVASIKLIEIVTHLSGLPAQPPDRGPSIGGNPFADYTEDRLCTSLLKLNGLPTRGRYSYSNYAYGTLGYALTLAIDPVNPPMKILSSEPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8B4</accession>
    <name>A0AAD8Y8B4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Delta(24)-sterol reductase</fullName>
            <ecNumber evidence="2">1.3.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_008500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.72" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8B4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000246">
        <property type="term" value="F:Delta24(24-1) sterol reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050614">
        <property type="term" value="F:Delta24-sterol reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008202">
        <property type="term" value="P:steroid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040165">
        <property type="entry name" value="Diminuto-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10801">
        <property type="entry name" value="24-DEHYDROCHOLESTEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10801:SF0">
        <property type="entry name" value="DELTA(24)-STEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="9">
        <location>
            <begin position="77"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1740405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="551" mass="63371" checksum="4BEAD836EE0D8BD2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8T2</accession>
    <name>A0AAD8Y8T2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ankyrin repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007494</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8T2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24121">
        <property type="entry name" value="NO MECHANORECEPTOR POTENTIAL C, ISOFORM D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24121:SF23">
        <property type="entry name" value="NO MECHANORECEPTOR POTENTIAL C, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="538"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="844" mass="93059" checksum="E12D0868AE5B990D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8T3</accession>
    <name>A0AAD8Y8T3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA pseudouridine synthase</fullName>
            <ecNumber evidence="4">5.4.99.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_007346</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8T3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050343">
        <property type="entry name" value="RsuA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47683">
        <property type="entry name" value="PSEUDOURIDINE SYNTHASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47683:SF2">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="3">
        <location>
            <begin position="92"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="343"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="345"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1741773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="364" mass="41102" checksum="4AB97D0C4FD947EE" modified="2024-05-29" version="1">MSELGICSRREAARILKDASESSNQRALKSVIYVRGSPVMGGTGFKVAQDEKYIEIRSGDAATTSNESHNDDLKEYVPYAERPWHEICGDSIVLNKPIGYVSGQEEHQHVPAVRLLTRSNNIDKDVDGIVSSSLQYTKQKWSGLDLETSSVPKHIRNTLNRDGKAVVDQDNKWEATLQGYACAGRLDINSTGVLIFTRAGMMARRLISPQSKITKEYIVKVAPAVQLTARESEMGMKLPPLTTDLESFLEGGRRLWDDAKPLKPVVEAEWLQNDPEEQPQIRTLRLVLQEGKKRQIRRMCRELLGLHVVDLVRTRIGPVKIDSLPEGKWRTLTKEEVQGIFMDRPKKKKKKGKKKRKSFVSIDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8U8</accession>
    <name>A0AAD8Y8U8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter, ABC-G family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_007220</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="562"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="646"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="682"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="758"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1161"/>
            <end position="1180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1192"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1239"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1275"/>
            <end position="1300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1312"/>
            <end position="1331"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="137"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="818"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="436"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="436"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="453"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1741647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1334" mass="146980" checksum="044AD50B94682DAD" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y928</accession>
    <name>A0AAD8Y928_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">propionyl-CoA carboxylase</fullName>
            <ecNumber evidence="3">6.4.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">QTG54_007758</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>propanoyl-CoA + hydrogencarbonate + ATP = (S)-methylmalonyl-CoA + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23720"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57327"/>
            <dbReference type="ChEBI" id="CHEBI:57392"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.4.1.3"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:23721"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate metabolism; propanoyl-CoA degradation; succinyl-CoA from propanoyl-CoA: step 1/3.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.4.1.3" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y928"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004658">
        <property type="term" value="F:propionyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06850">
        <property type="entry name" value="biotinyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000003">
        <property type="entry name" value="acetyl-CoA carboxylase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.20:FF:000010">
        <property type="entry name" value="Propionyl-CoA carboxylase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050856">
        <property type="entry name" value="Biotin_carboxylase_complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041265">
        <property type="entry name" value="PCC_BT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18866">
        <property type="entry name" value="CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18866:SF33">
        <property type="entry name" value="METHYLCROTONOYL-COA CARBOXYLASE SUBUNIT ALPHA, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18140">
        <property type="entry name" value="PCC_BT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0092">Biotin</keyword>
    <keyword evidence="4 19" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="18">
        <location>
            <begin position="65"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="17">
        <location>
            <begin position="194"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="16">
        <location>
            <begin position="730"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="41"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK1741280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="812" mass="88435" checksum="4726D8948DEB6D40" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9H8</accession>
    <name>A0AAD8Y9H8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">CCT-theta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">QTG54_007266</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03341">
        <property type="entry name" value="TCP1_theta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000008">
        <property type="entry name" value="T-complex protein 1 subunit theta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.132.10">
        <property type="entry name" value="Leishmanolysin , domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012721">
        <property type="entry name" value="Chap_CCT_theta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001577">
        <property type="entry name" value="Peptidase_M8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02346">
        <property type="entry name" value="chap_CCT_theta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01457">
        <property type="entry name" value="Peptidase_M8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13 16" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="18" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="8 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="734"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="857"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="737"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="747"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="active site" evidence="15">
        <location>
            <position position="1132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR601577-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK1741693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1924" mass="210896" checksum="B11C19C8274CA381" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YA75</accession>
    <name>A0AAD8YA75_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Translation initiation factor eIF-2B subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_007189</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YA75"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046523">
        <property type="term" value="F:S-methyl-5-thioribose-1-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="entry name" value="Translation initiation factor eif-2b, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43475">
        <property type="entry name" value="METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43475:SF3">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G14290)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="4">
        <location>
            <begin position="40"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1741616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="463" mass="51510" checksum="1073338482BE832C" modified="2024-05-29" version="1">MESIQEHKMKRTQNSSFRKPSRSPSNFKFKIIMRTATLSNIKRVVSVFFLRQNNNDEAQVALFRRCSQMPTFGGHWAAISGSIETQDVSPLATADREVGEETNLGELLGDYDHLLNSGLHIDIAIDKSKGTFGGRMIRVYPFALTLPSEDIQLLSNIEMRGTEHDKMKFLTISDFLGMSDQCVPSLKRAFHHATYGRYLDLPQEIREWEEDRVNGAAYLARKAVDLAAAHTQSGELSEDELSIAQSISILRPSMVPIVNAMNEFDRQIKHEGYGQIEQVKDELLKSLTDEGNRCVELGYELVMNMYKSKAPSTEFVIGTFSRSSTLKSILQRIIESSDDVSAKVRVVCSQSTPGDEGILMATDITGASCLPDEEFQQQVIDGKMDAVIVGADCVLSEGNGVVNKVGSKALASACKQAGVPIISSADRWKLWSDIHCPPLEDIFELIPSELFNHVLVPKDEEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAN4</accession>
    <name>A0AAD8YAN4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_007663</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAN4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050966">
        <property type="entry name" value="Glutamyl_endopeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15462:SF19">
        <property type="entry name" value="PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15462">
        <property type="entry name" value="SERINE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042258256" description="Peptidase S1 domain-containing protein" evidence="4">
        <location>
            <begin position="36"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="218"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="377"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="232"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="252"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="377"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1742090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="680" mass="74746" checksum="F5A396D8846CDC9B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YB41</accession>
    <name>A0AAD8YB41_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA-directed RNA polymerase II subunit RPB11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_007053</name>
        <name evidence="7" type="ORF">QTG54_013227</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YB41"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06926">
        <property type="entry name" value="RNAP_II_RPB11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00261">
        <property type="entry name" value="RNApol_arch_Rpo11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037685">
        <property type="entry name" value="RBP11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009025">
        <property type="entry name" value="RBP11-like_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008193">
        <property type="entry name" value="RNA_pol_Rpb11_13-16kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022905">
        <property type="entry name" value="Rpo11-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13946">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I,II,III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13946:SF16">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13656">
        <property type="entry name" value="RNA_pol_L_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01154">
        <property type="entry name" value="RNA_POL_L_13KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RBP11-like dimerisation" evidence="6">
        <location>
            <begin position="33"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1736091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1742488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="126" mass="14113" checksum="269F59B14EBF7CFD" modified="2024-05-29" version="1">MANAPERSSAFILDDDEEKIEYQADTKVSNAGTFTFNKEDHTVANLLRMQLLRDPAVKFAGYMHPHPLIHKINLKVQTSTSQVAPAETLSAAIEDLSNETDHLITQVTDAIEKWKRENDTMGMLGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YC36</accession>
    <name>A0AAD8YC36_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YC36"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="191" mass="20287" checksum="B0758E9F7C39343F" modified="2024-05-29" version="1">MATSSHKKRSRGSYGGDGSSSYLSSLPSSVNIMPSPTEKEEEYERAVAFLRNFHSTRVAALSPTSRSPLGAISEIGIGDLVNDFSLALQVESSSKTIKAGPSPLSPSRSPRIKKTTTSTCLLDLATTSSSGSTNSNSSANEKEVNDSSLFSLHQHARDEIFESCSTSSDFGVGYCGLNGLGNKRHCSSRIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YC44</accession>
    <name>A0AAD8YC44_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006038</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YC44"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011735">
        <property type="entry name" value="WlaTC/HtrL_glycosyltransf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09612">
        <property type="entry name" value="HtrL_YibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="560" mass="63824" checksum="B85FEC7B9A7A6C9D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCF4</accession>
    <name>A0AAD8YCF4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1743014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCF4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="255"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="522" mass="56346" checksum="FC60DEFC7088FCC3" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCR8</accession>
    <name>A0AAD8YCR8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_005359</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCR8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042262744" evidence="3">
        <location>
            <begin position="21"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="406"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="588"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="466"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="531"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="588"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1743762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="607" mass="66158" checksum="9327AFF558DFF11D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD65</accession>
    <name>A0AAD8YD65_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005665</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD65"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053038">
        <property type="entry name" value="RLP_Defense"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48064">
        <property type="entry name" value="OS01G0750400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48064:SF6">
        <property type="entry name" value="RECEPTOR-LIKE PROTEIN KINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="286"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="843" mass="93497" checksum="501A9FCA39032425" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD97</accession>
    <name>A0AAD8YD97_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DegT/DnrJ/EryC1 family aminotransferase</fullName>
            <ecNumber evidence="2">2.6.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD97"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244:SF34">
        <property type="entry name" value="DTDP-4-AMINO-4,6-DIDEOXYGALACTOSE TRANSAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="TRANSAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042109459" evidence="1">
        <location>
            <begin position="24"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="434" mass="47364" checksum="550FDDCC1639D1A4" modified="2024-05-29" version="1">MPATRFTKLALASIVALAAGTNALITNPVRTVITRDIKTPDPVPQSGIDEAVSLMTSGRMYRYNVKDSASSTVSKCEVEIAEYTGHKYCVALNSCGSAIMLMMKCAGLQPGDEVLSNAFTFGAVPSAIEHAGGKAVYVESNYDHVMCVDDLEKKLVEYPNCKFCLISHMRGKIADMDAVKDACDRHDVILLEDCAHSLGVEWKGTHTGHVGKVSAISAQSYKMINSGEGGFLLTDDAEIAAKCAVYAGAYEGLASKHTTVPGPEVFADLPTEIPNYSLRMSAIAAAVIRPQILTLDERREKYNKRYAFVTEKLVERKGHLLSIPVNTPGMTPVHDSLQFNLNHDITDEQVQNFLDEAATHGLPVELFGHKSNARNFVNWKFAPADQPLPLTAKMLTRACDVRLPLMWDDEDFETMVDVLCESLDAAIADEDVMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDC8</accession>
    <name>A0AAD8YDC8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006130</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDC8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041923928" description="Ricin B lectin domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B lectin" evidence="3">
        <location>
            <begin position="272"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1743509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="391" mass="42959" checksum="77268EBD6F575477" modified="2024-05-29" version="1">MKPKTQSYAAVVALTACSVALAGEVQSEDPNASSSLQPQESIDDKAINHRVVVEKKSASNHQTNVNRQTSRHLVPTGSSNYAPGCGLSTGTYHSIFLGCYDDHQDDRAFPFQVPSNGHGTLDCERACTSYRYFGRQFKGQCFCGSNYSQIVRHGTDSGCNCCGENVGGGKQCVWENTKHPESQLVEAPATAPAQALTPHSQLFASSAHVGSLSFGSTNIFGEPAKEPEQQSVAQVQNAPSASTTKPTRSFRLRLYWQRGYNWQNSSSEKWWCAECTGNCSSGSRLQIRKCSQTSRQQWAAVDKTIRFAPNTSLCVTASGVGSSNPIRLRQCNGGRDQKFDGVQEQGKFELQPSYNPSRCISQHHHPKDKEPLYPESCSKTRSTKTSYWQVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDK6</accession>
    <name>A0AAD8YDK6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005902</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDK6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="434" mass="49796" checksum="078D700A18486D02" modified="2024-05-29" version="1">MCEADVTPYWTCVYDELSRQDPIPLPLQRLFLCLVAIAYLPIMFPLTVGHFVGLDDSYFEFDKEHTFNFLTLMSVTTGLSPLQLYVCVSLTAAFFATLVWADITAIERPFRWPKVWETENNACYDDMFCEPSRKDRLIRRPGNTLSNFFYLFSAMIVLTSSYSRAFISEEKTSFILSDATFGTMMLILSISSTVWHGCNAMWSHGVDLWSMDAVIIYLPIRMMSLGVFVTLCKHSWDPIMASHIASAACMLIYAAHILSNGSRWKKKHDQKFWHKHFPFAVRNRLLHSPYVQTKKDDTINSLSLGPIPLYEVYLFALMPVIHNIPSWIMAKKVYESFGSVCFARILNISLAVGWAYRMTERWALDACRHIKFFGERMEMAKKNGEHIKSFSWMTLAAVLSPTAVLHYCTGITLTAAFCHARSVEIIMLQKFLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDZ8</accession>
    <name>A0AAD8YDZ8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Aldo-keto reductase family protein</fullName>
            <ecNumber evidence="1">1.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005304</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDZ8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1743707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="116" mass="13804" checksum="88B1D86C23D100AB" modified="2024-05-29" version="1">MHSPMRSYEETLRVWRVFESFVEENKVRQLGLANCYDQKTFLRLYEDSHIKPKVLQNRFYSQSGFDSELRDLCDAYGVTYQSFWTLSANREAIKSHEWKAMALNKNLLHKLSCMPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YE70</accession>
    <name>A0AAD8YE70_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005193</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YE70"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1743596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="601" mass="67541" checksum="BD0BF90F8AFF7F96" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEA8</accession>
    <name>A0AAD8YEA8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sulfurtransferase</fullName>
            <ecNumber evidence="4">2.8.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_004776</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEA8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate-cyanide sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01449">
        <property type="entry name" value="TST_Repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045078">
        <property type="entry name" value="TST/MPST-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11364:SF27">
        <property type="entry name" value="SULFURTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11364">
        <property type="entry name" value="THIOSULFATE SULFERTANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="60"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="240"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1744243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="364" mass="40060" checksum="07C41F79DA97F6EE" modified="2024-05-29" version="1">MMKRLCYIGIIATKCSLSSGFTTQTKTTHRLLFQTTRMMTATSNNNLVTIPDAITAHKQNSKHIKFIDGSWHMPVGDNPRNGRAEFTSGPRIPGAFYYDIDDIAPVMGSDDNPKKLPHMKPSSKMFASAMDQMGILPSDTLYVYATNDCAFYHRAYWTLRSCGHDPALVKLVQGSLDEWKECGGELEEGQLGEEDERLFRMSDLGWEEKTPTYQVMSDNEDVVVVDMDQVLDIVNQKDSDAADAVIVDARSAGRFVGTAPEPRPGLRGGHMPGALNVPFTDLLDADDKTKFRPMDEVRDIFIKAGISPDASNRKVVCSCGSGVTAAALAIGLEECGLRNKEDITIFDGSWIEWGSSDSTPIVTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFU9</accession>
    <name>A0AAD8YFU9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004793</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFU9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="679" mass="76550" checksum="F001567FB2FA354A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFY2</accession>
    <name>A0AAD8YFY2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_003306</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFY2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16448">
        <property type="entry name" value="RING-H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053238">
        <property type="entry name" value="RING-H2_zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14155:SF627">
        <property type="entry name" value="OS06G0192800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14155">
        <property type="entry name" value="RING FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="373"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="117"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="239"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="429"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="20"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="140"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="271"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="290"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="437"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1745382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="475" mass="51369" checksum="BAE5257598D37841" modified="2024-05-29" version="1">MFGESANFEKAEAEANNANMQPFTMNSRNLHSLFNDNPPNTAHGNLRMGNSTTDHYHRPAAGAGGIKDQAKAATVGDTTLGGQTDNQTLSFTLIFLSLMVVYIGFCCHYRKVKVRRSYDDSAHSQNANNNNNRQRRQRDNQAVLDESSSAANRAAADSEEQRKLEERKVRIGEVLWTRLIVDDEDEEGGHVAEPYLNVNGGGGDEENQVNANDDKIHEKSDLVDEEMGSEAAVVVGKTLAQDEDAPSGALATKQEEDEEAPYEETTIATVPSSSEETISTIPSNVPTIGTSPSSSTAVAPSTPPSSPFRKYADALSCNNCHHHATNYCNNQHINCNNDATTSSSPANSKSTSNNSSLTTITLSDIQQTYGDECNICLSTFQVGDRAAWSKHHFNGCVHVFHDECMKRWLLVRDGCPICRRLYLGEGTMKKGLVPTPQDDDGGGVDNDDGEGESGRDLESGGGGMGNAAIITVEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YH30</accession>
    <name>A0AAD8YH30_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004342</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YH30"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="77" mass="8116" checksum="8A12D2CA8960F86A" modified="2024-05-29" version="1">MVPAEVPQMQAAPAQDAAEKEEPPAQNETLDTQERHHSGGDGGSVYGRDDALPSAPAFYARSGSKSAILVHMIGQEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YH60</accession>
    <name>A0AAD8YH60_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mediator of DNA damage checkpoint protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_002820</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YH60"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17744">
        <property type="entry name" value="BRCT_MDC1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051579">
        <property type="entry name" value="DDR_Transcriptional_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23196">
        <property type="entry name" value="PAX TRANSCRIPTION ACTIVATION DOMAIN INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23196:SF1">
        <property type="entry name" value="PAX-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16770">
        <property type="entry name" value="RTT107_BRCT_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBA" evidence="5">
        <location>
            <begin position="430"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="6">
        <location>
            <begin position="492"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="6">
        <location>
            <begin position="605"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="203"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="243"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="298"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="243"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="260"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="298"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="363"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="422"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1746213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="708" mass="78898" checksum="34B392211C1A8B07" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YI14</accession>
    <name>A0AAD8YI14_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase</fullName>
            <ecNumber evidence="14">2.7.8.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_002260</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.5" evidence="14"/>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YI14"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008444">
        <property type="term" value="F:CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046474">
        <property type="term" value="P:glycerophospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050324">
        <property type="entry name" value="CDP-alcohol_PTase-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004570">
        <property type="entry name" value="Phosphatidylglycerol_P_synth"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00560">
        <property type="entry name" value="pgsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269:SF62">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="10" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="206"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="319"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="94"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="98"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1746916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="348" mass="36209" checksum="CB4656A01CE7F47C" modified="2024-05-29" version="1">MKYPMNLIAGVSVLLSSPVMSSSFSPAVFGRATSAFSKASNNGVKNAERMTFILRGGGEDDSIISSSSSASIINANGVNAGGVALSAVSNRGGEVEESSAAAPTTTSSSTKGGVGPNAPPPGPLRRLLPKFPWHELPNYLTYARCISIPIFLALSYYPVIMPNRAPVLSLLFAVASITDWFDGFLARRWDVTSPFGAFLDPVADKLMVSTALIVLAGRYGGIVAIPTAVIMAREVGVSALREWMAQRGARDSVKVGMQGKIKAALTMVSITLMLLVPEGVGLESVAWTKYLGVLGVGGAGSVVEGVVNDGLAWMLGPSLLMLFASAFVTVTSGSVYFKAAAPVLLGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJ71</accession>
    <name>A0AAD8YJ71_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_001271</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJ71"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045348">
        <property type="entry name" value="CPSF4/Yth1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23102:SF24">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23102">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="11">
        <location>
            <begin position="378"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="11">
        <location>
            <begin position="407"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="9">
        <location>
            <begin position="378"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="9">
        <location>
            <begin position="407"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="225"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="64"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="129"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="225"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="306"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1747308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="466" mass="51812" checksum="0DE7303CCCBFD8D8" modified="2024-05-29" version="1" fragment="single">MSRRFVRGAPPSSNGGGNNKWTASSSSSSYHHSARGRGRGEGRGRSFGRGGRFSNHSFVRNEAPTASNKWVRPTNTDAQVGDDNEADATINAKSDELADFPAENTIRDGSKNKDLSDAKAEETITSSSDVHKSEQNLERRGKHKLVIKKKNVTEIPSAGKVEGIIDPVPTESKAEEISSDVHKLDKHLERRGRHKLVMKRNEPNISSPIEHVAFLETKTEEKITLDVHKPEQNLERRGRHKLVVKKDETETLSKSNQKKNTEDTGNYSWKRKSAELSAPSNDEETDATKQDGIQNERAASRTSPPVKRKRPDKIHGPRRICISSAATEEGKDVDGMDEQPQKTMTDFQYKDASARGGRGRGRGKGKAMGLVRVKPKNPSETPICPTFSRGLPCNNAKCRLRHDVSTEASRPICVFFQRNGMCSKGDDCPFKHVKISWDTETCPTFERLGYCEDEGCVLRHVASKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YK08</accession>
    <name>A0AAD8YK08_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Acyl-CoA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_002036</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ACBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YK08"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000582">
        <property type="entry name" value="Acyl-CoA-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035984">
        <property type="entry name" value="Acyl-CoA-binding_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23310:SF62">
        <property type="entry name" value="ACYL-COA BINDING PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23310">
        <property type="entry name" value="ACYL-COA-BINDING PROTEIN, ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00887">
        <property type="entry name" value="ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00689">
        <property type="entry name" value="ACOABINDINGP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47027">
        <property type="entry name" value="Acyl-CoA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51228">
        <property type="entry name" value="ACB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="260"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="350"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="380"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="ACB" evidence="5">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="89"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="108"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="142"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1746692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="404" mass="43815" checksum="2A9F541953609AEE" modified="2024-05-29" version="1">MTAASNFRQKTHFMKSWKPQRPPSNRDRLELYALHKQSVSGDAPTSDPPSASVADKAKLTAWRSKMGLSQQEAMEAYVVECERQVQLYGTRDDGSRSSAGGGGGNSGIGATTSSSQQQQQNNQQQQQQQSSGAPASSQSTPMYHSTTPQNTPAAQNNSNNNNDDGVLLCPRGLAAIPLLCAAASESRSAYLARLQVTHPSNGWWAKQEPLCLEVNNPLSIPEKLIIGIACQIERISLVVSEYMGHGQAVSLLSPRVLQAFLWPVHNVFLSIWILWILVCTYLGSMVSMSQTLLFGAKRTNTPLGRLFLEEILPAARAVESLCEQHQTISVRMSGLALMPMMILCDVANGVVGRLGILVGSVVFVGMGACGWWYWLCVLPWLAVCSVCLAVMSGWCFGLIELSGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YK54</accession>
    <name>A0AAD8YK54_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_000025</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YK54"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16454">
        <property type="entry name" value="RING-H2_PA-TM-RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051826">
        <property type="entry name" value="E3_ubiquitin-ligase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765:SF434">
        <property type="entry name" value="GB|AAD18119.1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765">
        <property type="entry name" value="RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="110"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="58"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1748086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="183" mass="20083" checksum="5EEE2D80E039972F" modified="2024-05-29" version="1">MSALLDFMYYYAIFDYDRAVINNNSTTVSSHDDKKERMSKEDVNLIPEIIYDPTIDSETSVARHQSSSPPLECPPPSTKGARPSELAATESTLELSPPPSAAQSTNRAACAICILDYKAGDTLKILPNCHHAFHKDCIIPWLTERSGHCPLCRMTAHVGTKEGGSRHRSRSSGRCADVSCSIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKK1</accession>
    <name>A0AAD8YKK1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_002150</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKK1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050817">
        <property type="entry name" value="DjlA_DnaK_co-chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24074">
        <property type="entry name" value="CO-CHAPERONE PROTEIN DJLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="188"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="308"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="358"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="47"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1746806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="419" mass="46037" checksum="1AC2A938AAEAFFC2" modified="2024-05-29" version="1">MTDNIKISPTAPSRSTSTTSSSTTSSSAAPVALPSDEALELLLSPDGYYTYLSIPKPDPSSSLTNPYLDAAAAAGSSSTPENSIIDLDQVKKNYRRLSLKHHPDRRGGNEETFRALNRAKIVLSSPKLRREYDLIGLDLEDDAEDHHDDHHNASSDNASSDASKTENEDKEHTNNNNQNKTETVMSHLASATLAGVLQMVVRTALMGVVSVLLSRYTILTIVTLAMLVFLSTRIYSALNVAAKGANVKLNLLSLKDVGVPLLIAVGVYSMFRGRRFVMENDISGGEDNVVVGDGTTTVQETIYHSWTWTFWFGETLVMTLFIANSFEKRSPALLALFTTISGIFALWLRGQFWRYATLLGFQGVIALLVVLAFPIMEMILEQIVEEKMKKVGEKIRAHDARLRELQRKRNVGAAAASLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLK9</accession>
    <name>A0AAD8YLK9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Geranylgeranyl transferase type-2 subunit beta</fullName>
            <ecNumber evidence="9">2.5.1.60</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_000567</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21240"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11537"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57533"/>
            <dbReference type="ChEBI" id="CHEBI:86021"/>
            <dbReference type="EC" id="2.5.1.60"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the protein prenyltransferase subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.60" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLK9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005968">
        <property type="term" value="C:Rab-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004663">
        <property type="term" value="F:Rab geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072657">
        <property type="term" value="P:protein localization to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02894">
        <property type="entry name" value="GGTase-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.20:FF:000012">
        <property type="entry name" value="Geranylgeranyl transferase type-2 subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045089">
        <property type="entry name" value="PGGT1B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001330">
        <property type="entry name" value="Prenyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026873">
        <property type="entry name" value="Ptb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774:SF11">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00432">
        <property type="entry name" value="Prenyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Prenyltransferase alpha-alpha toroid" evidence="10">
        <location>
            <begin position="16"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1748628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="402" mass="43928" checksum="C7C2131822DE19D7" modified="2024-05-29" version="1">MTSETAAPVGPFYDALHANYIVTLGDKLDSPTSYEGAVTEHLRVSGVYWSLAALALLRTEGEVDDLMGLTKPIQAATDGTDENKIRSAIVDWVFQCYDARVGGFGGNCSGENPHDAHLLYTLSALQVLAISNSLDDERLDKDAIANYVSSLQNEDGSFSGDEWGEIDTRFTYIAFSCLALLGKLPLPDWNNSNSTQVVSEEKPIIDTYKAVKYIMSCRNFDGGFGCVPGAESHAGQVFTCVGALSIAQSLHLLEDADLLSWWLAERQCDSGGLNGRPEKQADVCYSWWILSALSILGRVDWINTGKLGQFILNCQDDEDGGIADRPMDMPDVYHTFFGLCGLSLIGQLEKIGNKEGQNYRQIDPVFALPTDVVSRLGLKAQVIRNGGVDVEKRLQLHSILDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3Z9</accession>
    <name>A0AAD9D3Z9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_017063</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000078">
        <property type="protein sequence ID" value="KAK1732238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3Z9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21113">
        <property type="entry name" value="AGAP001705-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21113:SF4">
        <property type="entry name" value="CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="286" mass="31092" checksum="3098AC08EC1CFF23" modified="2024-05-29" version="1">MGGRHVLLDGISPALQYRGWKYMDELQKFVEGGMQGTSFIDAVSGIVNRGCHNPPCGTGAVDGGYERSQNFKKVLETFFDASLPEISPLGTSLGLSPLFTSFNPDALPPSLKSSSPSSVDVPQPVLEHVDSADADPTQDPVSSSDTQINHINDVPTHYCNEQTNLPSDSKAVDVVYQYEVVLSHPIDLQEALLKVKKEVVASLADSLGCITESMRRSLRDTVHNNTLIGIQEGIAKVDTGKESCSMASFSGCIPIVSHLTGYLTILLQMKTFRKQKTKLYTLFNRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4D3</accession>
    <name>A0AAD9D4D3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Adenosine deaminase-like protein</fullName>
            <ecNumber evidence="11">3.5.4.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_016674</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(6)-methyl-AMP + H2O + H(+) = IMP + methylamine</text>
            <dbReference type="Rhea" id="RHEA:16001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:59338"/>
            <dbReference type="ChEBI" id="CHEBI:144842"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:16002"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; purine nucleoside salvage.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.-" evidence="11"/>
    <dbReference type="EMBL" id="JATAAI010000062">
        <property type="protein sequence ID" value="KAK1732613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4D3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004000">
        <property type="term" value="F:adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006154">
        <property type="term" value="P:adenosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046103">
        <property type="term" value="P:inosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409">
        <property type="entry name" value="ADENOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409:SF42">
        <property type="entry name" value="ADENOSINE DEAMINASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="5" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Adenosine deaminase" evidence="10">
        <location>
            <begin position="30"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1732613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="443" mass="50699" checksum="63EEB121578F486C" modified="2024-05-29" version="1">MTTTNNNNSNTSPSSTIINQQLHGFTKSLPKIELHAHLNGSIREHTLIELASERNVTLSPKMILHDAESAQQHNDDSKEERLFWNTHPRFWNTRPRNLQDCFEVFEYIPKCVNDLVALRRITEEVLMDAAEDGVVYIELRTGPKCLLRRHHDDDGSGEGGGIMATKREYVETIVEIMNEFEKKERNRYEMEMECRAQDNMMQQQQIVRLALIPRLIISVDRAGTIEQADENINLAIELFQKQQMLPPGQSKYIVGVELGGNPTRNDFTIFEASFERARRAGLYVAIHIGEVPMKSYDAKYNEALAVINFRPDRLGHALTLSTSLIELLEKNPIPIECCPTSNTMTLDFASHHKGSLIDGIKMHPHLKKWIECNYPISINTDDSGIFCTNLTKEYMLIAKVFELDERKLSEIVLDSVEHAFDDDIKAKLRNDIQSMVEMMVAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D682</accession>
    <name>A0AAD9D682_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_013789</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D682"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1735626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="337" mass="38912" checksum="E0778334748EE68B" modified="2024-05-29" version="1">MADHHEAAADDRDNIMFVYTGGRVPEHLRLHITHARVDESVTEIDEGAFDGCEHLLDVDCHNGLNNIRAFYLCRLLRRANLPGVTFIDQSAFEYCSRLKDVKFSSRLETIETWAFGNCRDLTHIKIPSILRIDYGAFFSCKTLAEAEFGEGLETIEEGAFQYCHSLRRIAIPLKYDLFTLNSNERYDQFDDCYKLATVELVGSIHKTITFLSLQNWRNEMNQEISRINEVLPNLSTFEKAGEMRDWIRRVLRRIEHYKAEHSNLLKEAMVLLELAVWKAKLRQNEEEKHSVLDSNKAKKIKLDLESARHGHRVTCGADIIIKNVLPFLELPKGDDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D692</accession>
    <name>A0AAD9D692_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013819</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D692"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051024">
        <property type="entry name" value="GlcNAc_Chitin_IntDeg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34823:SF1">
        <property type="entry name" value="CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34823">
        <property type="entry name" value="GLCNAC-BINDING PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042229112" evidence="2">
        <location>
            <begin position="20"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="846"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="851"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="933"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="950"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="963"/>
            <end position="996"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1112" mass="118259" checksum="D5E1CB4E46E37140" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8B9</accession>
    <name>A0AAD9D8B9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8B9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="125" mass="13894" checksum="5576E69B5F084EA4" modified="2024-05-29" version="1">MRATLKYPGWALFVYLLIGQGLPAMNYDLGVRMGFALGDLIFYIPLLGFGLLTSNYVALSAALGITTYWPIVCLAAAINAQDVPGWSLDDTPFLIVLPMISMWGLWCLLLISHDLRKGKKKHYID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9B5</accession>
    <name>A0AAD9D9B5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010347</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9B5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052394">
        <property type="entry name" value="LRR-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114">
        <property type="entry name" value="LEUCINE RICH REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="71"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="535" mass="60412" checksum="5438866326032352" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9G3</accession>
    <name>A0AAD9D9G3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011517</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9G3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="161" mass="18147" checksum="B8B5E775A9EC0E5B" modified="2024-05-29" version="1">MHPVCSILRERDDGTTRWLSGITTTSTMRYDLASASSLWYSNQDEGDVFKGLKKMTKSRNKNEACPFVIPTIVSQQKDVVVVQEEENRQDDRPQYHEDSRIGFICVGPSTLSSKLESNMLGWDEHSYGYHGDDGSTFHRGKSSSDEMVLPVLDVVIRLDVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DA38</accession>
    <name>A0AAD9DA38_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pre-mRNA-splicing factor 38</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_009555</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for pre-mRNA splicing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the PRP38 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DA38"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005037">
        <property type="entry name" value="PRP38"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23142">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR 38A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03371">
        <property type="entry name" value="PRP38"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0747">Spliceosome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="125"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="184"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="136"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="184"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="232"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1739796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="276" mass="32212" checksum="F7C5F725B28CA46E" modified="2024-05-29" version="1">MANVTDPLARTVHGKDPQNLIEYITRQKIYDSIYWKEECFGLSASDVATKAIQPEDGILEEFLMNEDFKYVRALGAFYLRWKITHVDEFADELLTSDRYCGIALPHLPKRDVLVSAGYLDGPRRSALTPLMEEQSEEKRKREVEEKERSFREQVGGRESSRDGRRHEDESDRLYRARRDDRMRVGDRDGYYSQDRDERTYDRDERHQSSGIDKRKKEKKDKKYGSLFKKSSSKSEKDQYKSKGIKSDEGGDGNGAEDIDYWNAERAKLGLKPLKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAB8</accession>
    <name>A0AAD9DAB8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Choice-of-anchor L domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009001</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAB8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049804">
        <property type="entry name" value="Choice_anch_L"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF038133">
        <property type="entry name" value="choice_anch_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="363"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="307"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="385" mass="41283" checksum="31A264405B5A4D1C" modified="2024-05-29" version="1">MKIASFALALEIIIRIDRAVASFPTRPNFTTPNEDEDASASASVFASSALNFTAMTKEELIENFISHNGEVEFSNITASPHYGNCTRYFTGGYSVGYAYENDGNTNLTDVHLLPDEGIMLSSGNPLDFEWNDSDGQTTFWGFLGLDLSDADLANVTNTTYGIYDACFIEFGFKCSNEASTPTVSFKYMFGSDEYNEYVDSPFNDAFALILNGENIAKLPSSESSTDVVSINNVNNQLNTQYFHTNDPSDGTIYPQLEADGFTVVLTAVGTPSQDPNEMNTIKIVVGDAGDQALDSWVLLESGTFSCGGPSPGSKSSKRGYSSKSSKGTSTSTKSAKYTKTNAFGSSLQAQEMKASASLVSNSPVVGCGVTVFAILVLAFAFDPLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBZ1</accession>
    <name>A0AAD9DBZ1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Flap endonuclease family protein</fullName>
            <ecNumber evidence="3">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007484</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBZ1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09869">
        <property type="entry name" value="PIN_GEN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041012">
        <property type="entry name" value="GEN_chromo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF59">
        <property type="entry name" value="FI23547P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18704">
        <property type="entry name" value="Chromo_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG-I" evidence="2">
        <location>
            <begin position="119"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="478"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="561"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="622"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="478"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="579"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="625"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="642"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="653"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="687" mass="76413" checksum="CEF97E3EB0B68364" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCH2</accession>
    <name>A0AAD9DCH2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peroxin-13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008793</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCH2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="224"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="360" mass="39000" checksum="CC4386919EFE1641" modified="2024-05-29" version="1">MTSSTPMVVSSSVANGGIRNNNRTIASPAAAAGTQKRKNSTKSTSSMVVKKNSSKPTKKEIPVDDEINTDETTAAAAENNVNTSTTSNNMLGGAGMMGGMGMGVGGMGMMSPMMGMGMMSPYSMGGMGMMGMGGMMGSQWLMSLNQFLFGIQSVVFSIGQAVQIVGMNAQQMKHMYESVKGMVENAIGQVNSWGQMEKWEEITGVKGDDARRWMLGGDNDENDSNNSNSQVQQEQGDEERKILTHNEIIRRRRLAAFRWTMTLTVSYFLYRGVRRLIRMVLYGSRGNGRRQLASSDMHMQQQYNGMGGMSNQYYGGGQGSYGMGGQGGYGMSRYSSYGGGGYGRRNYNAGYQDMGGGDYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDU1</accession>
    <name>A0AAD9DDU1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Coronin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006944</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDU1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015505">
        <property type="entry name" value="Coronin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10856">
        <property type="entry name" value="CORONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10856:SF0">
        <property type="entry name" value="CORONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16300">
        <property type="entry name" value="WD40_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01167">
        <property type="entry name" value="DUF1900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="174" mass="19251" checksum="76AD6B760BA1CF7A" modified="2024-05-29" version="1">MPMYDADTDVIYLCGKGDGNIRTCEFEDKAPYFHKLNDGFRSTVPLKGVCMVPKRGLDIMQCETVRLLKVTNEQGVQPLSFTVPRKSDAFQPDIYPNTASNVPAHTAQEWWGGSSKGPKTMSLNPRDKSTNGAGKAPKKFQSVATLSSDVKKLETRIRYLEGKLDAAGISYDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEC3</accession>
    <name>A0AAD9DEC3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEC3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="130" mass="15424" checksum="41637B8F86C60A56" modified="2024-05-29" version="1">MRRESSTRTPKLLRWGTIIGSVLFHRWLPCQVLRRRENIDRDTQRVLAYYKHAAANSFHDGDERQARYIVWKYKGKKDALWRRLEAKYGVPVKHAWEWDDEEEDGAKDDDEAAEDLDGEGEECEMKGEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEP5</accession>
    <name>A0AAD9DEP5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fructose-6-phosphate aldolase</fullName>
            <ecNumber evidence="3">4.1.2.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006607</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1743010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEP5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018225">
        <property type="entry name" value="Transaldolase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683:SF40">
        <property type="entry name" value="FRUCTOSE-6-PHOSPHATE ALDOLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="TRANSALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01054">
        <property type="entry name" value="TRANSALDOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0704">Schiff base</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042175158" evidence="2">
        <location>
            <begin position="30"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="258" mass="28037" checksum="49ECBFA012446C40" modified="2024-05-29" version="1">MKVAPARINHLSIAALATLLLHIFPLSLSFTPPHRGGCRLFLDTADTNEWDALLPRGMFYGVTTNPTLLERANEPCTVENLHKLASTALQYTDEFMCQSWGATADDLFQTGMAISEYDRERVVIKVPVTATGAEAASKLTKAGVRICFTACYNKKQALIAASSGVEYIAPYLGRITDNGKDGYDECRQMQNIVDGLGSGTRILVASLRDADTIAKLAMEGLDTFTFNPDVAREIFDEPLTDNAAEEFEEAAARGGTSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEV0</accession>
    <name>A0AAD9DEV0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005796</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEV0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041991461" evidence="1">
        <location>
            <begin position="23"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="360" mass="39737" checksum="757C9DE2AE57AB48" modified="2024-05-29" version="1">MGFVQHLIILSALLLIQTESFSFRPDPAPSAQLDRREALKATLGFASVLLSPLTSNAIDYSDDQQGIGVITDSSIGKAFRRSVVRGAQVADKLDEGWEKLSDGLRDKSKCDKNTGRRLYDNGVRKDGTPIGNPGLGALCSLATLVSATKEDYLQKAIQDTKDLVRPSFERSMIGSDEEKRKKSFNFEFYSVMRAITNVLGERRVSVRDFQLAWGRELVSMYAPSANRKDYSSPFPKIDEFEDYDYDKNKLLDALGAVTVTLDAFKSGGILGFVEISIPYDDYGSVVTVAVDDYVPITAEILLSEQKLLSQGPIQALVVYLLENASIAFAADTFYLDPSTTSQTAYNPTQLLLSLSNLRKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFP6</accession>
    <name>A0AAD9DFP6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005027</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFP6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041989818" evidence="2">
        <location>
            <begin position="22"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="557"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="733"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="151"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="257"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="323"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="573"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="845" mass="89109" checksum="14CE358B6C391A60" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG95</accession>
    <name>A0AAD9DG95_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005056</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DG95"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07040">
        <property type="entry name" value="HP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041933305" evidence="1">
        <location>
            <begin position="20"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="264" mass="28265" checksum="56D825614AB768E5" modified="2024-05-29" version="1">MNLIGGFVILFAMLVSTSARSDSKASKSKSTKGTKASSNTNTIVYLFRHAEQQRTTTTLGTATSAYDVVWDGDAVDISAIDGDTIGSNYDDACGSTHCAEELNPLGLMRASMLGQWFQDNGILSSTTDIFATSKRRTQQTVLPAAALAEMTVQTFPVDGTELDPQSASRTTCPTIDAIKNVSNGSQILVASHTSAIYQIMGPGVAGECTGFGIDISDDDIFPKDDRGSVPRAEYGFIWKFSIDAEGNAQFLKRIDFKLNLITEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHU5</accession>
    <name>A0AAD9DHU5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Isoprenylcysteine carboxylmethyltransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_002765</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHU5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052527">
        <property type="entry name" value="Metal_cation-efflux_comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007318">
        <property type="entry name" value="Phopholipid_MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43847">
        <property type="entry name" value="BLL3993 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43847:SF1">
        <property type="entry name" value="BLL3993 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04191">
        <property type="entry name" value="PEMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1746158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="168" mass="19300" checksum="68AE11AD7EA83CDC" modified="2024-05-29" version="1">MNKTLSAHPRCIHRTSEFLGILLCAAAYILQHSYPLAFFSYRSDQSSCIHVYKAIGYLLLVFSAAILKSTQIEMATYGQPHEPGKPTTALITTGPFHYSRNPTYTAIILFLQPGLALVFGSSWLVILLPISYGLFWYVMVKPEEEYLQEKFRVGGEWRKYCEHTRRWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DI48</accession>
    <name>A0AAD9DI48_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phenylalanine-tRNA ligase alpha subunit</fullName>
            <ecNumber evidence="7">6.1.1.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_000630</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DI48"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009328">
        <property type="term" value="C:phenylalanine-tRNA ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002319">
        <property type="entry name" value="Phenylalanyl-tRNA_Synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF40">
        <property type="entry name" value="PHENYLALANINE--TRNA LIGASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01409">
        <property type="entry name" value="tRNA-synt_2d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phenylalanyl-tRNA synthetase" evidence="6">
        <location>
            <begin position="2"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1748691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="188" mass="21622" checksum="0AFEDC9CDEE9D521" modified="2024-05-29" version="1">MQMGFEEMPTSKWVESSFWNFDSLFQPQSHPARDAHDTFFIKEPAATVSVPEDYYERVKTMHESGGSGSIGYRYDFKREEAFKNLLRTHTTAISSQMLYKLANQEGGFQPARYFSIDRVFRNETMDATHLCEFHQVEGLVADYDLSLGDLIGTMRPSSKRLVSQNCVSSLRSTPTQSHPWRFSDIILI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DI79</accession>
    <name>A0AAD9DI79_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA-binding protein 28-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_003125</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DI79"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051945">
        <property type="entry name" value="RRM_MRD1_RNA_proc_ribogen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN 14B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039:SF5">
        <property type="entry name" value="RNA-BINDING PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="15"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="175"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="358"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="39"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="122"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="267"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="502"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="744"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="844"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="267"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="291"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="302"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="317"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="340"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="502"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="744"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="780"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="798"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="808"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="849"/>
            <end position="860"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1746518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="869" mass="95907" checksum="D69C18FE98EEC601" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIG2</accession>
    <name>A0AAD9DIG2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000316</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIG2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="5"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="99" mass="11257" checksum="06732C897FE06C7C" modified="2024-05-29" version="1">MNAAHKRFESMEKALQESINRLEKEKEKLVAAHDVEISSQIKQHDKTRIELSAWKLEMQNALNDIETLKRENDDLRNSFDAVSQANGSSSQSKVETASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJT5</accession>
    <name>A0AAD9DJT5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquitin-activating enzyme E1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000723</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJT5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.60:FF:000001">
        <property type="entry name" value="Ubiquitin-activating enzyme E1 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.60">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, UFD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018965">
        <property type="entry name" value="Ub-activating_enz_E1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038252">
        <property type="entry name" value="UBA_E1_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09358">
        <property type="entry name" value="E1_UFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00985">
        <property type="entry name" value="UBA_e1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-activating enzyme E1 C-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="105" mass="12126" checksum="76543F99FB38EEB8" modified="2024-05-29" version="1">MTLSEPTPPAKTTAMLKGEKWDWTAWDSFDMNMGDITLAEFIQFFESEYNLDVSMISHGVSILFSFFANKKKLAERMKMKMSEVVANVTKKELPPNQLLLFRNHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJV5</accession>
    <name>A0AAD9DJV5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000798</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJV5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="419"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="481" mass="52548" checksum="930E55D98744388C" modified="2024-05-29" version="1">MKRLFGFRAAASSPGKVNGSARHPADDDGNASSAVDDGGSSASDDDSENGSYDASQSSDSGCSDDESSLASLESMTSVGSIQYLFQKVGRSFNAVRSRSINAVKLSSPSRTKSNTENMIIRNNSSSVRAVPEEAAVNHGVNDECTDSDFEHGLVEGDHVIRWKMLGYLYPIQIHGIVLSAGPDIVTLVDFGLTSVKCYDKVGKFDEEAEIKVNKYNKTRRRMNVITLAEEKEIKKWTKVRYGDEVEIKVYNKLRDGRNVDGGGVASSDPSGLEMEKTDVNEIQSSSSRCRELTNKKTPEKNMLKLPSSDPSKLVLARLRFLLEHGEEEQSEQKKNISTLLPPHHLLYANSECIAVWVKTGHWSTLQGSIFLHSSTVGNAKQTATLAMYLSAQTATVPASGLWGWLGGTTTVSLFTAQPWVVPALIGGGMVYIGLPTMLLWKAKGRWSETEKKLNDGFWSSADNETIVALVQNWKCFSEASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRA2</accession>
    <name>A0AAD8XRA2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_017067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000078">
        <property type="protein sequence ID" value="KAK1732242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRA2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="446"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="209"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="469" mass="49737" checksum="A672813427ED74A3" modified="2024-05-29" version="1">MTVGGVGPSTQRQRSYMLSCWGKGGSFFVLRHHHASCSSLTTICFIWLRTDSLCFRLSFSTGINFELELSASAASNYEGIEIVARDRDRDNRTGVDPETGIRSKSVDGSTNTAISRPRRGYYGKSKYAGAVAVLLVAGTGVGIWSSMNQKKKMEENKSIATAIAATKTIKSAKSKAKAGGKPKISKSKSSKAPSSEPSNLPSAMPSLIPTESTEPSSFPSLIPTQPPTPAPTPSGPQTASYDATLGAPKCSHGLSCDSAGLLNGRGTMFNGVETNRPNNLNSCTDGGSGTYHDDESIDRIIVTRVTGGDGDLTEGDEVTITASVWCWSTGSNSFIDFYYASDASNPVWNQIVPRERCPGGGQQTMTASVVLVQGSLQAVRANFMFGSGDPGENSCTSGNYDDTDDLVISVKPNLAAQGIFATPGKSKHDDVQGQGAIVYVEKDAEADEMEKKLQQMNQSKEKPAEDDGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTK9</accession>
    <name>A0AAD8XTK9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Deacetylase sirtuin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_015669</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000046">
        <property type="protein sequence ID" value="KAK1733626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTK9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1733626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="77" mass="7947" checksum="29D44E9A0701BBA5" modified="2024-05-29" version="1" fragment="single">AADGILCIGTSLAVHSAYRLAKRALDKGTEVAILNVGETRIESEGLDSSTGLVTKIESPIGDTLAEVVKSYTAAAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTX8</accession>
    <name>A0AAD8XTX8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Leucine-rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015942</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000050">
        <property type="protein sequence ID" value="KAK1733383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTX8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="224" mass="24366" checksum="FEF4C72F437A6F10" modified="2024-05-29" version="1" fragment="single">MMMAADGYYTFTGRDGEVIPPGVTRVRIHESITVIPAAAFNGNPSIEELDCHDRVKTVGESAFFNCPSLRIVRMPGVKVVKRCAFMSCIALTDVECGKLEIIGFGAFDGCALTCINVPSARIVGGGAFYECDALTKVKFGKELESIRVGAFYCCTSLERITIPLKDGMITRNDIFQGCENLKHVDLVGGGGVHETIAALLLEGWKYDLKEKFYAINQILPNTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XU00</accession>
    <name>A0AAD8XU00_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XU00"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042223574" evidence="1">
        <location>
            <begin position="27"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="141" mass="16322" checksum="CE876AD59BA6E0A1" modified="2024-05-29" version="1">MMHRRAPTILLVMISWWGLFVWFSSTRLNGYTPPKNNDQQIGKGSGYGDVHLISSANTFSGVQIQTCTPDQLLLIQQQLPPHDCETNKRQPWTQQCSFSYATQCPDATWIEDFYRKKHKTKSNRNETFTGMFVGCNKEWMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV22</accession>
    <name>A0AAD8XV22_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_014980</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000040">
        <property type="protein sequence ID" value="KAK1734213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV22"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="225"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1734213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="283" mass="32128" checksum="8EB9049E71BC46CF" modified="2024-05-29" version="1">MGRKRNQGKARKAAKAKAKEEERGNNNNNQRRNERQQSLAALLQQLQSGAASDTTLCRHGFEQIDKMCTDLVIAFRDAFYDNTDGGDADILDCLIAAEDATMDKFADVWNNSAKMEIAISSLLSMGTEYVLCVLDGNYVSARDFATFARYFEQHVAVKLHQTQALVNFPKICETYHVAGSPFDKQKHPSDLHTLVKFFRKRIPCCCLDEKYEEVKGVTKMGWCFNLQCNLLRVERSKTMYCDRCRFVTYCSPECQKAHWSKHQATCDAKAAAKAKFEAKQQDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV56</accession>
    <name>A0AAD8XV56_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1734060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV56"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031052">
        <property type="entry name" value="FHY3/FAR1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31669:SF251">
        <property type="entry name" value="PROTEIN FAR1-RELATED SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31669">
        <property type="entry name" value="PROTEIN FAR1-RELATED SEQUENCE 10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="996"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1002"/>
            <end position="1014"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1022" mass="113713" checksum="3EAB6A89C08B658E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVD1</accession>
    <name>A0AAD8XVD1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ankyrin repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015113</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVD1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24121">
        <property type="entry name" value="NO MECHANORECEPTOR POTENTIAL C, ISOFORM D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24121:SF16">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="294"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="397" mass="44592" checksum="86DCDBE761C847E9" modified="2024-05-29" version="1">MPLHCLCENIHIDDAASLAILKLLILKCPEAIRHANNDGELPIHLVGGWKSPEFCRLLIEAYPGSERITNAGGALPFYCACSYNTRATVEYLYKLYPDAINHTSRGFYPIHYAITGVKQRVHPIAALEVVKYLLDCDPNVKLQKIRGKSLLHYACRKRYNDSNIDAALEIIEAIYDTHPEAIEENRIASDIQRYHQQVQTFINSQLVYSRQAKDRHVMTTPDDNGRLPLHTALQNNVRLGSIKLLVKGNPHSLQTPDNSGTLTLHMACQHHNSANVIQYLVGLDATTLDAVDREGNTALHYACHYARHEIIALLLDKFDAVSVSKRNSQNKLPIDLLWESSAVEVEDKDSVEYTESVFRLLAAYPETLMNIGIQKPLSAFNNACPGQSGRKRKFGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVD6</accession>
    <name>A0AAD8XVD6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015136</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVD6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="211" mass="22892" checksum="175E3AEB7C07C6A5" modified="2024-05-29" version="1">MSFATSAPKVAQAVTATFATYCTADFLSNFIQHPTQKMDYGFLNSFIGREVDQPFWGTRTQHIIGVAGCLAITDHTSQALFQKVFKKELCFAKSPAAFVAHTFLFIFSGVTLYCAGDAALNPNHKEEDRMTTFKSETYNSYVGSNTAWFEPYVPVAVAKLAGPAAGSSWLGSALLPATLAYSTVKGVGWNDWGNSGLNELEEKMNGVGVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVV9</accession>
    <name>A0AAD8XVV9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphodiesterase</fullName>
            <ecNumber evidence="3">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_014910</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="3">Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cyclic nucleotide phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1230:FF:000017">
        <property type="entry name" value="Adenylate cyclase type 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023174">
        <property type="entry name" value="PDEase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16305:SF28">
        <property type="entry name" value="GUANYLATE CYCLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16305">
        <property type="entry name" value="TESTICULAR SOLUBLE ADENYLYL CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00126">
        <property type="entry name" value="PDEASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="5">
        <location>
            <begin position="693"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="5">
        <location>
            <begin position="1026"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="341"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="433"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="529"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="964"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="350"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="539"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="573"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="597"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="964"/>
            <end position="974"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU363067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1734403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1471" mass="162610" checksum="96E5CEA6E554BF06" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWC2</accession>
    <name>A0AAD8XWC2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6824 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014523</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWC2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049227">
        <property type="entry name" value="DUF6824"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20710">
        <property type="entry name" value="DUF6824"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6824" evidence="2">
        <location>
            <begin position="18"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="120" mass="13038" checksum="43F48053429F7AD8" modified="2024-05-29" version="1">MASGSPPLTGVTKITENDIICGRGGVALKHPGNLAYRKIVGLNKGIYATCLKVEKLKISKSIVAAIREIEGRFLEREDGKPTSSLDERDENGNPVTWKDIGDKRAIEKTSQALRRASQSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXG3</accession>
    <name>A0AAD8XXG3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2256 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013876</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXG3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017136">
        <property type="entry name" value="UCP037205"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37463:SF1">
        <property type="entry name" value="DUF2256 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37463">
        <property type="entry name" value="GSL3115 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10013">
        <property type="entry name" value="DUF2256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="280" mass="31870" checksum="9E2CAE3CA4D78452" modified="2024-05-29" version="1">MVIQQLVRVSIYSSAFIHQGRPGPYTYTQHRYSIQRRCTSNSFINNEIDLEAMPRGVKKENLPVKTCTVCNRPFTWRKKWEKVWDEVTTCSTSCNRKRKETNRQLNKTIHDSSNVEDPFVAIRENINIGCTESSIDDKEQLLNNMDSVLESDFDGEDQLLDSICGDMLAMEIGAQDDSSISESDAITDAKAKRKAEKKRKKAERRAQREGRGDPTAGQKQCTLCAKSVNLLIRCQHDKSGEWAMVCGKCWNDVSGGVVDGDDSHPYYRYGGLWKNRRAQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXU1</accession>
    <name>A0AAD8XXU1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">pyridoxal kinase</fullName>
            <ecNumber evidence="2">2.7.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_013620</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pyridoxine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.35" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXU1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008478">
        <property type="term" value="F:pyridoxal kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009443">
        <property type="term" value="P:pyridoxal 5'-phosphate salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01173">
        <property type="entry name" value="pyridoxal_pyridoxamine_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013749">
        <property type="entry name" value="PM/HMP-P_kinase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004625">
        <property type="entry name" value="PyrdxlKinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00687">
        <property type="entry name" value="pyridox_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10534">
        <property type="entry name" value="PYRIDOXAL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10534:SF2">
        <property type="entry name" value="PYRIDOXAL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08543">
        <property type="entry name" value="Phos_pyr_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyridoxamine kinase/Phosphomethylpyrimidine kinase" evidence="7">
        <location>
            <begin position="81"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1735457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="332" mass="36675" checksum="8C6630A4BB9051C2" modified="2024-05-29" version="1">MSMRVLSIQSHVVSGYVGNKAAAFPLQLLGFDVDVINSVQFSNHTGYGSWEGEVLQGDMLLKLVDGMDENGLSNETGHILTGYIGSESFLRAVVTIVRKMKVVNPQVRYVCDPVLGDIGKFYVPEQLVKIYKDEVVPLADVLTPNQFEVEQLTGVRIENINDAQRACGILHDLGVPLVLITSIIFPTNAQQSQDSMGVFASERFMLQNVSCGIETESYEDEQRILYVPKMPGQFTGTGDISAALWLALTADSTSSLAQKLEQLAGTMNAIVERTYQASLEKLQKQGISSLEEPKDEATRKRIVRSREMQLIQSASDILNPPLRFQATKISER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XY14</accession>
    <name>A0AAD8XY14_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Brix domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013708</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XY14"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045112">
        <property type="entry name" value="PPAN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12661">
        <property type="entry name" value="PETER PAN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12661:SF5">
        <property type="entry name" value="SUPPRESSOR OF SWI4 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Brix" evidence="2">
        <location>
            <begin position="35"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="407" mass="46035" checksum="E8BD5BC1C43EEF06" modified="2024-05-29" version="1" fragment="single">MPRRGRKRKKTRTHVVDTDERIRGGLLSNDELKIPRSLVIRRGKVESELTELVTDIRKLMRPYTAVNFKEDAKNRKVTLSHYANSLSTSMGVTHILAVSQNSNRVTLRVGRTPGGPTLSFRVKRFTLGRQIRSVQRRPYDSTKAFESPPVVVTNNFGDVSAAPHVKLMRITFQNMFPAINVSTVKLSECRRVVLFNFIRRDMSQVSSDKKKHVGDDDDLEDEEVEIRHYAIRAKPVGVDRKVRRLVEAKIPNLSKLSDISDYITGQTSSGAPAPAVLRPGEMSDSEPEDEDTQVVLPGKYRGKGNNQAQKSALKLVELGPRLRIKLYKVERGMASGDVMYHAYENKTPEEVKALKQRKEGEAALKKRRREEQEANVARKQAAKDEKLAAKKARKKEREEKAMAALRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYI3</accession>
    <name>A0AAD8XYI3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Iron-sulfur protein NUBPL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_013115</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1735979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYI3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2020.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010376">
        <property type="entry name" value="GBBH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038492">
        <property type="entry name" value="GBBH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000808">
        <property type="entry name" value="Mrp-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044304">
        <property type="entry name" value="NUBPL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961">
        <property type="entry name" value="IRON-SULFUR PROTEIN NUBPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961:SF2">
        <property type="entry name" value="IRON-SULFUR PROTEIN NUBPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06155">
        <property type="entry name" value="GBBH-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01215">
        <property type="entry name" value="MRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma-butyrobetaine hydroxylase-like N-terminal" evidence="5">
        <location>
            <begin position="252"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1735979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="344" mass="38106" checksum="7676991A5775055D" modified="2024-05-29" version="1">MSFGYVNEGSAVMRGPMVTQLLDQFLSLTNWGPLDYLILDMPPGTGDIQLTLSQRLNITAAVIVTTPQELSFVDVERGVEMFDTVNVPCIAVVENMAYFEKEKSANVEVDYETLRDKFLQVLKERDGISDEAAADVVNSLVDTVQENVQNTGKGEMEEIRIFGQGHKRRLSEQWGIEHTFSVPLVSTIAKNGDSGTPFILDNPSSPQADTYKELAKTVARETSKVLFSKTSRPNLSYLSEAHIIQVDGMDQGTLAPAELRRGCRCAACVEELTGKQILNPESIPESIRPMSMSPTGNYAVSVDWSDGHKSLYPYRQIRSMLASKNTNDEVLDGNMEKEKETVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYR9</accession>
    <name>A0AAD8XYR9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sulfotransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013329</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYR9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040632">
        <property type="entry name" value="Sulfotransfer_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978:SF4">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17784">
        <property type="entry name" value="Sulfotransfer_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="397" mass="45227" checksum="F34D63C92FFE4589" modified="2024-05-29" version="1">MIVTSTNNRQRRNDGGGFSTTAVLKLILSAAAVGAFMNLWAFQSYYSEDDIHLTHHDVDDDVVRPSDNGWRADEIEIREEWERPTDDGWVEDESAVQEEWEPILENNSPSSVDEEDTDDVNTAADDNATEDDKAKTDKTDDKDTEQLSPFYSSKSCFKARSNTVPEHLYGKLQKPYFNLGFPKMGTSSLHKFFQCGGLDSVHYRCTRLDSCARCMRESVEAGGLPLDYCELPPRKIDMYAQMDDGHYFPQIELLDELVDGYPKATLFLTFRSMEKWYNSLRKWPPRRNGPHMNDKLKQHNITGFPSGVGNNVDEFADWYCNHVDRVRDIAASNPSLTLVEVDIEDSTIAKRMSDMFDIDESCWGHTNVNPIANPDLDLSEVQVSQKYNQIVNKKASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZM5</accession>
    <name>A0AAD8XZM5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_012710</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZM5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00499">
        <property type="entry name" value="Ribosomal_eL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001380">
        <property type="entry name" value="Ribosomal_eL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018256">
        <property type="entry name" value="Ribosomal_eL13_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11722:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01294">
        <property type="entry name" value="Ribosomal_L13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01104">
        <property type="entry name" value="RIBOSOMAL_L13E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1736688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="207" mass="22907" checksum="CD74A1C0F2CF982B" modified="2024-05-29" version="1">MVKHNNVVPNIHCHKKYCESSRGPLKVRLTLNQAGKKKSRRLARAAKAAAIAPRPLKLLRPSVHCQTQRYSAKVRLGKGFTLEELKAAGLTARFARTVGIAVDHRRTNKSAESLAANVARLEEYKTKLIVFPKKRLSKVKNGDSSAEECKAATQFKGVVMPLAKASNEIVMADIPTQDISAFTQMRVARKETKVAGFRCSVANREEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y053</accession>
    <name>A0AAD8Y053_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Hexose transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">QTG54_012523</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>D-fructose(out) = D-fructose(in)</text>
            <dbReference type="Rhea" id="RHEA:60372"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:60373"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>D-galactose(in) = D-galactose(out)</text>
            <dbReference type="Rhea" id="RHEA:34915"/>
            <dbReference type="ChEBI" id="CHEBI:4139"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="7">
            <dbReference type="Rhea" id="RHEA:34917"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>D-glucosamine(out) = D-glucosamine(in)</text>
            <dbReference type="Rhea" id="RHEA:78423"/>
            <dbReference type="ChEBI" id="CHEBI:58723"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:78424"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-glucose(out) = D-glucose(in)</text>
            <dbReference type="Rhea" id="RHEA:60376"/>
            <dbReference type="ChEBI" id="CHEBI:4167"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:60377"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-mannose(out) = D-mannose(in)</text>
            <dbReference type="Rhea" id="RHEA:78391"/>
            <dbReference type="ChEBI" id="CHEBI:4208"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:78392"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-xylose(out) = D-xylose(in)</text>
            <dbReference type="Rhea" id="RHEA:78427"/>
            <dbReference type="ChEBI" id="CHEBI:53455"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:78428"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y053"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015149">
        <property type="term" value="F:hexose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045263">
        <property type="entry name" value="GLUT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503:SF8">
        <property type="entry name" value="FACILITATED GLUCOSE TRANSPORTER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="18" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="117"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="279"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="376"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="412"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="441"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="470"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="504"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="532"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="17">
        <location>
            <begin position="122"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1736501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="617" mass="67428" checksum="2BC50BDFFA4413C9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0K3</accession>
    <name>A0AAD8Y0K3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0K3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="365" mass="40680" checksum="E26E35D8175D1478" modified="2024-05-29" version="1">MILKSSLYSAAGVALLSSAATDAFVPSKGTTRALLEVRSSLDRDWDNSDFLSSLSGGSDEIAEVNAKYQAQSQSRAKINEWRALQMQKEMESSSTPLNASNESGDYGPTPELLRKMMGDENIRQQAPPETQQAPAVPPPPQQPQMQQQQFYDANGNPIDMTMVYDANGNLVQFYPPPPPQQQPMQQQPEQEQVPSMNYDALMQQDTDPPMQQQQLMQHLCPEDSTPSVEPVPLEPPLPPNPKTLGDEPRPQGYNEDAYAVSNTADVYFAQLKQDSRVRKRAWLSGDKDTANQVFTDPTVTVIKDQWVDNPYTREKNIQEARAEIEGAVRMQHDSDDESTKFSSSGVSYKEKLEQIKAKRRGDGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0U5</accession>
    <name>A0AAD8Y0U5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DEX1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_012194</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0U5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056376">
        <property type="entry name" value="DEX1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045232">
        <property type="entry name" value="FAM234"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21419">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21419:SF23">
        <property type="entry name" value="PROTEIN DEFECTIVE IN EXINE FORMATION 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23722">
        <property type="entry name" value="Beta-sand_DEX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="Integrin alpha N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042238367" description="DEX1 C-terminal domain-containing protein" evidence="7">
        <location>
            <begin position="33"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1079"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="domain" description="DEX1 C-terminal" evidence="8">
        <location>
            <begin position="975"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="106"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="175"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="357"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="443"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="574"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="119"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="381"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="449"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF23722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1737327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1127" mass="125138" checksum="9B8B5A59B24CCFF4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1F3</accession>
    <name>A0AAD8Y1F3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytosolic iron-sulfur assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_011928</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MIP18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1F3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.130:FF:000004">
        <property type="entry name" value="cytosolic iron-sulfur assembly component 2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="entry name" value="Fe-S cluster assembly (FSCA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039796">
        <property type="entry name" value="MIP18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12377:SF0">
        <property type="entry name" value="CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12377">
        <property type="entry name" value="CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="Fe-S cluster assembly (FSCA) domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIP18 family-like" evidence="4">
        <location>
            <begin position="149"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="41"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="15"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="54"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1737642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="286" mass="31358" checksum="B86DE33200F0BC4D" modified="2024-05-29" version="1">MQSSAKENPNPVVHTTQRSTSTRSSLSQSLGYEAIRRYNLGAPSPTISTTVDESSSPFTSSSSYLSAPPTAEEHSVAIALSEAAYEPNSDSSLDLLQRAGFALFHPQRIHKECRAIRFPSYSPASVKNPARPSSSSLDAQHSRDEITSEEVFDIIRNIQDPEHPLTLEQLNVVRMDMVDVVDLSVTNDANAMDGQKRKFSTVHVQFCPTIPHCSMATLIGLSISVKLLRSLPPRFKVSVKIEPGTHVSEHAINKQLADKERVRAALENDHLLGVVNRCIAGGMKMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y225</accession>
    <name>A0AAD8Y225_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Spermidine/spermine synthase family protein</fullName>
            <ecNumber evidence="8">2.5.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_011266</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y225"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010487">
        <property type="term" value="F:thermospermine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006596">
        <property type="term" value="P:polyamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.90.10">
        <property type="entry name" value="S-adenosylmethionine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003582">
        <property type="entry name" value="ShKT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43317">
        <property type="entry name" value="THERMOSPERMINE SYNTHASE ACAULIS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43317:SF1">
        <property type="entry name" value="THERMOSPERMINE SYNTHASE ACAULIS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01549">
        <property type="entry name" value="ShK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01564">
        <property type="entry name" value="Spermine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00254">
        <property type="entry name" value="ShKT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51670">
        <property type="entry name" value="SHKT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PABS" evidence="6">
        <location>
            <begin position="176"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="ShKT" evidence="7">
        <location>
            <begin position="1012"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="83"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="331"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1737972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1058" mass="118521" checksum="0CC5D4E5494F9DF3" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2H5</accession>
    <name>A0AAD8Y2H5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011098</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2H5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042292709" evidence="1">
        <location>
            <begin position="20"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="137" mass="15514" checksum="238B7FFFF2E25522" modified="2024-05-29" version="1">MRKLISTVVAIIVLTEVHGRTPGWFYSVRGGTGLLPNMMYPDALTSVVHGCAELDKETDDKQVQHTKLSGITKKVVKTASSVSHERVDNELFEKLNDKIFHHQQDHDDRSDNDEEKPAVAKISYGAREFLLEDDMYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3Q5</accession>
    <name>A0AAD8Y3Q5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF1275 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010233</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3Q5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010699">
        <property type="entry name" value="DUF1275"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37314">
        <property type="entry name" value="SLR0142 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37314:SF4">
        <property type="entry name" value="UPF0700 TRANSMEMBRANE PROTEIN YOAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06912">
        <property type="entry name" value="DUF1275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="254"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="450" mass="49207" checksum="D9E7BA0F2D69D16D" modified="2024-05-29" version="1">MPMSTGEQTAAAAADNHDNVELACSSGGENDGKKTSPIDFSGPPPPKSMQEHTKHGYMFTVTVGLLMAFSAGYSNAVCLGGFLNVGADSATQSVAGVTGVYTNSAIFLVEPDYEQMSFMFGTIFSVMFGAFLAAIMNPYPIAFEISPRYGPTFLLGSLFMVVGATEAVHNDRREFFFTAIANGLMNGVSSMYSANLLRTSHLTGTTTDIGLFLGMALRGNRTNNWKLYILIGLAVFFWTGSVCGYVASQMKRQYSLIFNACFLFLLSVSVTIRTCILYHGCTKWTDALDHLDVVPKNQEADGTENDDRLSEDELEKIFDEIAALSEDGEVDQHLLLAYLASQDLKVKKNRKGLVGLLHHAFVTRGDGDWKLDKEEWKDLVHQSIIHQSMMNSAMLNQSMMTTHMTKESIRKSSKNLYSSIKNIDGASTSAVAGPEALRQLSIMQLGASLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3V8</accession>
    <name>A0AAD8Y3V8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009749</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3V8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="244"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="271" mass="29815" checksum="F52A3E6F73B2BE0D" modified="2024-05-29" version="1">MQEVAEEDPEEGAWAATPSTVGEEEATPLIDHSSGVIYGSPLTNMMSYTASSSFPSSNTTCSSAVTPRFSNVTLDDEDMLNDPPPRVPSMSSTTSHPTSSHFRAMRSSRVPPPRQSSSIRHPVSNGSANNNNNDTLQYNTVNNNHHHRPATLTRPILPQRPPQHQHHSTRSSRIKTSTTLIILVLGLFLAICTLFQYFVMGPDSFNLPSDLDLNNNDGGSTIGDHGEEEGGSSKAKKKKYRMRMLFCLMSLGGILLRIMMLILLSQIFCRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4B3</accession>
    <name>A0AAD8Y4B3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010601</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4B3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="2">
        <location>
            <begin position="140"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1082" mass="122811" checksum="24553DC356F2E06D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4G1</accession>
    <name>A0AAD8Y4G1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009835</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4G1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="102"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="85"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="183" mass="21282" checksum="60F2EBD19F47C2F5" modified="2024-05-29" version="1">MVLEEEDEEVEDVSEEDDPDPEEEDDDAEDDSEEEEGEDEDVVFPAPTAKAKLLKSLFGFKTSSLMSKGRTDVKVFGKTVRKQRQHSEKEKARERQAVQNLREGLLTAKRDLKQRRKEHKKQVERLKRQCELQENDRSYDKSLTSMEQRTSALEEGQLELLVLAKQQMKLIENLTERHARAHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4M7</accession>
    <name>A0AAD8Y4M7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA topoisomerase 1</fullName>
            <ecNumber evidence="3">5.6.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">DNA topoisomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_010766</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the type IB topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4M7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.11.10">
        <property type="entry name" value="DNA Topoisomerase I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.15.10">
        <property type="entry name" value="Topoisomerase I, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.41">
        <property type="entry name" value="Yeast DNA topoisomerase - domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013034">
        <property type="entry name" value="DNA_topo_DNA_db_N_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013030">
        <property type="entry name" value="DNA_topo_DNA_db_N_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001631">
        <property type="entry name" value="TopoI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014711">
        <property type="entry name" value="TopoI_cat_a-hlx-sub_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013500">
        <property type="entry name" value="TopoI_cat_euk"/>
    </dbReference>
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        <property type="entry name" value="TopoI_DNA-bd_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036202">
        <property type="entry name" value="TopoI_DNA-bd_euk_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013499">
        <property type="entry name" value="TopoI_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051062">
        <property type="entry name" value="Topoisomerase_IB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10290:SF3">
        <property type="entry name" value="DNA TOPOISOMERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10290">
        <property type="entry name" value="DNA TOPOISOMERASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01028">
        <property type="entry name" value="Topoisom_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02919">
        <property type="entry name" value="Topoisom_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00416">
        <property type="entry name" value="EUTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00435">
        <property type="entry name" value="TOPEUc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56741">
        <property type="entry name" value="Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52038">
        <property type="entry name" value="TOPO_IB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="DNA topoisomerase I eukaryotic-type" evidence="11">
        <location>
            <begin position="294"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="49"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="113"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1738736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="514" mass="58145" checksum="8F252640B5FE010E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4N7</accession>
    <name>A0AAD8Y4N7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Guanine nucleotide-binding protein subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_010781</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="AlphaFoldDB" id="A0AAD8Y4N7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002307">
        <property type="entry name" value="Guanine nucleotide-binding protein G(k) subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000692">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF302">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-5 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0807">Transducer</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="430"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="447"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="87"/>
            <end position="92"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="233"/>
            <end position="234"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="258"/>
            <end position="264"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="283"/>
            <end position="287"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="352"/>
            <end position="355"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="411"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1738751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="850" mass="95831" checksum="675CE685FD4EF8E9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4P3</accession>
    <name>A0AAD8Y4P3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carbohydrate-binding module family 96 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_009415</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4P3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055372">
        <property type="entry name" value="CBM96"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF033679">
        <property type="entry name" value="DNRLRE_dom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24517">
        <property type="entry name" value="CBM96"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Carbohydrate-binding module family 96" evidence="5">
        <location>
            <begin position="125"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate-binding module family 96" evidence="5">
        <location>
            <begin position="320"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="86"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="104"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1739656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="482" mass="53377" checksum="44D4D0950BFF056B" modified="2024-05-29" version="1">MTELTANVRYGEAIYFPDFAHRCCRGEKEGDHAFKPTWMTSDHMFQNKELCCTEQFDWVELDRCLGIGFVEMNVFRETPAIVEDLDDAGNTTENTLALPRKPTSRPTTSMPSVSLQPTRDEGVAVQALADTTVSQNNANKNYGSHSMLVVDGGMAGVQQKYDTLVKFDLSFLESGMSFGKVFLRMFVKDAASDFCGRFDTTQNAYWNEDSTTWMNAPTSSTGMNIGEAWNAVSGEWFELDVTGVLARQEQKLLSIRISSTEPKRCIFSSTSDPGRAPYLFARFSKQEQETPALPGLTSPPTLPPAPVPTHRKHGEALMLFASDDTTISKEEPHLVSGKEATLVVTDDEFSTKDILLKFDISEMRKTTPRSVILMLHVPQNCMSAGVFVSTSRHGNGWTEDTVSWSIAPTFQYGGDGHGTEIGAFGGELEGGKYATFNIIALMSWYTVNYQDIVTIRISSNNGHHCEYTSKEGGNPPKLVIQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5M8</accession>
    <name>A0AAD8Y5M8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Methionine synthase reductase</fullName>
            <ecNumber evidence="11">1.16.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_009397</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.16.1.8" evidence="11"/>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5M8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030586">
        <property type="term" value="F:[methionine synthase] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050667">
        <property type="term" value="P:homocysteine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF84">
        <property type="entry name" value="METHIONINE SYNTHASE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0288">FMN</keyword>
    <keyword evidence="10" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="9 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="13">
        <location>
            <begin position="38"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Flavodoxin-like" evidence="13">
        <location>
            <begin position="269"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="14">
        <location>
            <begin position="596"/>
            <end position="866"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00039088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00040659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1739638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1070" mass="116819" checksum="93676AE521A15D40" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5Q5</accession>
    <name>A0AAD8Y5Q5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF306 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_010065</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protease inhibitor I13 (potato type I serine protease inhibitor) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5Q5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009611">
        <property type="term" value="P:response to wounding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.10.10">
        <property type="entry name" value="Trypsin Inhibitor V, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005184">
        <property type="entry name" value="DUF306_Meta_HslJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038670">
        <property type="entry name" value="HslJ-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000864">
        <property type="entry name" value="Prot_inh_pot1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036354">
        <property type="entry name" value="Prot_inh_pot1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33091">
        <property type="entry name" value="PROTEIN, PUTATIVE, EXPRESSED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33091:SF29">
        <property type="entry name" value="SUBTILISIN INHIBITOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03724">
        <property type="entry name" value="META"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00280">
        <property type="entry name" value="potato_inhibit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00292">
        <property type="entry name" value="POTATOINHBTR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54654">
        <property type="entry name" value="CI-2 family of serine protease inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0722">Serine protease inhibitor</keyword>
    <feature type="domain" description="DUF306" evidence="4">
        <location>
            <begin position="105"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1739522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="303" mass="33605" checksum="305573EDED678C3F" modified="2024-05-29" version="1">MKQLPQRTTAVIKIYSTATTTTSISNTNEKNTYQLISSKIKQAMRLSNLPSLGLASILFNALQSTAHEPILRGGQLPIPEAPSPEFGNELQDTPVVKDLYLDTFQLAGSNWRASNIRGALLGSDADVTMFFKSKTSVEGSGGCNQFDASWEKLGTLIQINGTEQPLILEHMRVEDLAPTRRYCDGMMAQVENYFFRGLTQDSLFYEFDGEELTLWDAVMGENGRQTRGMFIGRFNNVHVPSWGGQSLVGMTGEEAKAAIEDINPSLQVQTIPEGSMMTMDHRLDRVRIFVGEDGNVNREPQRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5W6</accession>
    <name>A0AAD8Y5W6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009193</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5W6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="131" mass="13821" checksum="E6AEA9D484611565" modified="2024-05-29" version="1">MLGRAGSNSVLIPYSSVAGVFTLIRLWQHLGPNTYTFWGGTLFLVFVLSGVGFNVLYGMICVEFLHVAIGGSFVGAMIPFTIALWNAELPGPTDVDSGEVIKGVVGYVTSLLSGRKDDAGYGGLSENTSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y659</accession>
    <name>A0AAD8Y659_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008549</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y659"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="475"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="197"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="535" mass="59225" checksum="EF61617FF37B9D46" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y665</accession>
    <name>A0AAD8Y665_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CAP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_008546</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y665"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041926361" evidence="2">
        <location>
            <begin position="23"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="3">
        <location>
            <begin position="309"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1740451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="497" mass="54532" checksum="F53276C322DCB58A" modified="2024-05-29" version="1">MMIKSTTLFLAIGSIVAAASNSADVPPSISNEDWDYQVVGEARSADEDRGLLRSNTECITIRMKGDGNADKNSVLLEDLTDGTTISDGPGTLPAGIWDSPCLQAPDGNLLKLTIDTPSGYSSTAFHAVFVGTFRFIRVAGGEKNDVDVRCFRLTANHPFVEDANCDDAPSQQSSNSGGGSSGGPPVQQASTLPFTSRMGCGSGEKKIQVTFEKDSYNENKWWIQKKNTNNKVLECDGNGAYCESEVVDACLEADDYEVVMRDAIGDGCPKFELKMEKSGGGWSHPLIARCYNGKEWKRHFHTKPSTMTPREVDWLDAHNERRQKYYYDGNSIKSNGNDNYIPQVWDSRLAEMAQGYANRLLDDCESNEMSHDSTRQGAGENMAKNRGTVGSAYGSQYPAGNIVNRFVEAELDKPFGERYHLTQVLWQASGYVGCADGFKEYVFGGVTKHCHTQVCRYSAPGNCGVNANNDFEKMMYSFDELNCGGDMKNPPDGMHAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6A1</accession>
    <name>A0AAD8Y6A1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sel1 repeat family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008933</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1739983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6A1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1739983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="129" mass="14736" checksum="86A822E2C4CE7A1A" modified="2024-05-29" version="1">MICNGCNYANRMRELEGNVQQKCPFCRHPRAKSQKEAERDLMKRAEANDPVYMSQVGVRCYQEGDYKGAFGYLTKAAGLGDAVAHFQLSCMYYDGKGVQKDKKKEVYHLEQAAIRGHLRARHNLGFIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6B4</accession>
    <name>A0AAD8Y6B4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Quinone oxidoreductase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_008563</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6B4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003960">
        <property type="term" value="F:quinone reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE PIG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106:SF13">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="3">
        <location>
            <begin position="93"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1740468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="450" mass="49116" checksum="00BD6FAA336B22B8" modified="2024-05-29" version="1">MDANKQRWTILGQDPEILLAALANILSWFVVTFCPRFLPYLLPSSPEEEQDGDAISIDATRTRCISIGRPGGMEQLRLVTLKKDICTIGYNVKHVSPAPYTPADGFELPDDCVVVKNLAFSVNYADCTIRWGLYESAKKFVGYPIVPGFDVAGTIERVPKNNNSNFKVGDRVFGCTLFGAYSSRVVIPTIQLRKIPDCIDSFSKAASFPAVSLTALYALHLAGYFPGGFDEGASRHKFKNKSILIHSAAGGVGSFLVQMSKILGLGPIVGVVGRSSKVDEAYRLGCDAVIDKSSEDLWSAATKACPDGFSTIMDANGVSTLKESYNSLAPSGRLIVFGFHSNLPLGQAMLNPLEWIKMARKQSNMPKFNAMDLTVSNKSVLGFNLSFFADEREILSDMFDQILEWISNEKLECPNVVEMEMKNIALAHEFISSGKSIGKIVVTTEPTSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8F2</accession>
    <name>A0AAD8Y8F2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Histone chaperone, ASF1 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_008545</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ASF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8F2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006335">
        <property type="term" value="P:DNA replication-dependent chromatin assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1490:FF:000001">
        <property type="entry name" value="Histone chaperone ASF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1490">
        <property type="entry name" value="Histone chaperone ASF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006818">
        <property type="entry name" value="ASF1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036747">
        <property type="entry name" value="ASF1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12040">
        <property type="entry name" value="ANTI-SILENCING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12040:SF0">
        <property type="entry name" value="HISTONE CHAPERONE ASF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04729">
        <property type="entry name" value="ASF1_hist_chap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101546">
        <property type="entry name" value="ASF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="167"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1740450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="202" mass="22328" checksum="5DBD4DF7FB42B24C" modified="2024-05-29" version="1">MALVNVVNMAVLDNPASFLSPFSFEITFECLQPLSDDLEWKVLYVGSAEDTSHDQVLDEILVGPIPVGINKFVLQADAPDISQIPEGDVLGVTVVLVTCSYREKEFVRVGYYVNNEYTEEYDEEVGPPKPLDMSKVRRSVLAEKPRVTRFPIQWGDNKDEEIENVQQNGQGGMEGQSMEEAKMAGANGGGETDSMMVDAVME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8L7</accession>
    <name>A0AAD8Y8L7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008214</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8L7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="158" mass="17840" checksum="721060CCEF88D8DB" modified="2024-05-29" version="1">MGKSKRTSSRNVLETLAAELWVREVNDAVKSRYADSNGVAMVCEDHQRKESRFQVGVAKSKIDQLMKGNNDEEDFVRSKSITFLKDATNDEGSGKRCVKDYLRAIAADIDPNYKEKTMARAAGLWSGYFGDRDICDDESVEVQSCMCVEKKSFVIGYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9I2</accession>
    <name>A0AAD8Y9I2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007983</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9I2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="93" mass="10420" checksum="48A5E470D622AA3F" modified="2024-05-29" version="1">MTTPKKTFFQRFGPPALARGLWGNRSMPTKYKLLFVGQSVIFTMAMWVRGEDVERAQARKKLEDSEKQRAEITTNAVAANAAPSEDNKSADNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YA10</accession>
    <name>A0AAD8YA10_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TMEM70 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007372</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YA10"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033615">
        <property type="term" value="P:mitochondrial proton-transporting ATP synthase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009724">
        <property type="entry name" value="TMEM70"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13281">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 70, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13281:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 70, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="232" mass="25263" checksum="E7B37EC43DEFA95D" modified="2024-05-29" version="1">MIRISTFRLASSLKGVKKIAPAARCSLCVPADRVATIPTPLQLRALSTTNEDKEKEPVVLYEGPFASLTLRLKRVSLTSAVIGIVGLPALSFFYGAADSVPATGQVAVIATAGLTAVGSTVLLGYCFSPYVHTLERVAADAAQDKNDQLIRMVTRDILARKVETIFDPTKDVAAPSSSNSRPFCNFMVHGLPFYIHPQMVHDDELRVQLVGEEKQNEVDNKNKTKTDDDEFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAY5</accession>
    <name>A0AAD8YAY5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_007313</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAY5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1741740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="168" mass="18503" checksum="DEDA872C416A250B" modified="2024-05-29" version="1">MKMSFFDDMGKFFDNLGGGDEESGASSKVEIVDGAYTGSKRIISIPAKTMKMGGLRLYCNLYLMGVQNTPEPGCWKASKSDDSEVNLRYVDLSGSIIIQFSEECITVDRLGSSPSNKYLMHESMILNGFLDELNSIVYEGSVSEEKRLLTLPEPGNQLEEARDAISFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBA7</accession>
    <name>A0AAD8YBA7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Rossmann-fold NAD(P)-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006594</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBA7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43490">
        <property type="entry name" value="(+)-NEOMENTHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43490:SF99">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1742997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="354" mass="38659" checksum="47A92920917DD8CB" modified="2024-05-29" version="1">MMPELRSKVSFTMASSSLTILSFLLSTLGFASALAAAAAPMRSYLITGANKGQGYALCKRILSEYGDTHVYLCSRDVQRGREAKESLLTESECDIHPDRIDVLQLDVTSDTSVQDAMNTVRLNLGPDDKLAGVVSNAGILWGYPLPELMEVCAVGVRRVLDAFVPLCQEEDGRVVVVTSGLGPLMHSYASEEHQNALKSDDCTWDDTISPLITKCISAYETTESSLEERIAAFDKISFPGGPFSDSAPDFHMYGLAKMFGDAYMLHVAKNYPKLRVTSVDPGLVYTDLILKMPKYAGKEIDDTTAQTPEEGVEATMRLLFDDEAGKGEDGSGKLYAMKDGKLVFSDIDKMPQKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YC13</accession>
    <name>A0AAD8YC13_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Trafficking protein particle complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_005993</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Part of the multisubunit transport protein particle (TRAPP) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Golgi apparatus</location>
            <location evidence="7">cis-Golgi network</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAPP small subunits family. TRAPPC4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YC13"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030008">
        <property type="term" value="C:TRAPP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14856">
        <property type="entry name" value="TRAPPC4_synbindin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007233">
        <property type="entry name" value="TRAPPC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23249">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23249:SF15">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04099">
        <property type="entry name" value="Sybindin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01399">
        <property type="entry name" value="Sybindin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="5 7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1743372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="193" mass="21048" checksum="3E624A8B1548520E" modified="2024-05-29" version="1">MGFLHLFIVNKSGGLILHRPLGPSAPKINTNDWLRIGSTFHSLHAIAAEASPVKLPGNKNPGENRVYVLYFELLQSATYIAVRIKVCSSHLVCCTSINTTNVLAGADDGIEEIEGGGVILKCLQTRTGIKFVLTAEPGTADLDSVLREIYVLYSECALKDPFYELEMPIRCELFTLAVDGLIERLESGGVKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCP5</accession>
    <name>A0AAD8YCP5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FH2 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006237</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCDC53 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCP5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071203">
        <property type="term" value="C:WASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2220">
        <property type="entry name" value="Formin, FH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015425">
        <property type="entry name" value="FH2_Formin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042201">
        <property type="entry name" value="FH2_Formin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019309">
        <property type="entry name" value="WASHC3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13015">
        <property type="entry name" value="PROTEIN AD-016-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13015:SF0">
        <property type="entry name" value="WASH COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10152">
        <property type="entry name" value="CCDC53"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02181">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00498">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51444">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FH2" evidence="3">
        <location>
            <begin position="343"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="125"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="186"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="258"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="68"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="125"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="157"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="186"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1742640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="809" mass="92010" checksum="E92ECB5436625612" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD43</accession>
    <name>A0AAD8YD43_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Vacuolar calcium ion transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_005878</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD43"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF22">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="122"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="210"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="440"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="503"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="536"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="564"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="9">
        <location>
            <begin position="60"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="9">
        <location>
            <begin position="440"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="242"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="306"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="340"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="390"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1743257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="610" mass="66158" checksum="BDA94D914023CA12" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDU5</accession>
    <name>A0AAD8YDU5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDU5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="176" mass="18844" checksum="DED6671AD8B66947" modified="2024-05-29" version="1">MSRGFSSSPHNNTNNNGNNGDGTDNGDAVLLAEGKVVEVTNHFDAAAAISAALASSHLAQATGVDESSISRSAANDKMQSYKRTSSSDSYARVKKGLPTPAEAAAEMRQRRTSYESLDESDRGAEMVHKTDEAGDVETTGQQAESVGEKEADDEQQMSKKNEESDPKEKMETRRNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDW3</accession>
    <name>A0AAD8YDW3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005006</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDW3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="208" mass="24062" checksum="230975136FD535B0" modified="2024-05-29" version="1">MKDHEARMRVFYYNHHLAINDKESSAIHVYRYDDSKKDKAWRCLDRIYPGRVYVDEDEVTHSRETKCDARILRMLLTDDRGSFLVGFGVKLPTERDYTASHGALHYYTLNDEGEYVLKQAVKLAGKHIWNGSVVGIAVDGETMILSVQEPWERSVAVKYTLVCGVWKEERVINRERAIGSNLQLLGNKFIATYSDNAEFYTLDEEAFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YE90</accession>
    <name>A0AAD8YE90_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_005457</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YE90"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046964">
        <property type="term" value="F:3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778:SF8">
        <property type="entry name" value="ADENOSINE 3'-PHOSPHO 5'-PHOSPHOSULFATE TRANSPORTER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08449">
        <property type="entry name" value="UAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="177"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1743860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="242" mass="26909" checksum="2D64291432F92F42" modified="2024-05-29" version="1">MVFHELALESINVVYSQPPYSFQYLTSSITLFQFGFCVILPATLSMTCAGGDVISNFPREWKQFFVYVKLSAVVYGATALATMSLAYSGVTYVTRKHYSVWDYGSALLLCVGAAGFCMSPKSDDDTSSNIMEDTKSDEMMESVANTQGPHWIGISLLIGSVFCDAFVPNLSEQLMQQGTMGRTKAINRKDSGDEDDDEEVEMKSLLSSNNADTNNSHYEHSQSQTQKKKDCRQLHLWSTQTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEG4</accession>
    <name>A0AAD8YEG4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WRKY transcription factor 19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005676</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEG4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="154" mass="16877" checksum="AB53750E67BFFB8B" modified="2024-05-29" version="1">MSKKRDSSALSNQKAFAFAADTRDETSASMDSDERNTQSDRKRKPSSTYMELPPKKDAHLMGVLIKSSKVEHGATWTKKKCSSEGCSNFAKNGGVCLKHGAQKRLCRMEGCMNGVKNGGVCFMHGAHKRLCRMEGCMNGVIKGGVCIRHGAYRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEH7</accession>
    <name>A0AAD8YEH7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_006131</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEH7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042165377" evidence="7">
        <location>
            <begin position="39"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="8">
        <location>
            <begin position="265"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="59"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="773"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="77"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="106"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1743510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="825" mass="89029" checksum="13F135C839CF0911" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YF98</accession>
    <name>A0AAD8YF98_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">E2 ubiquitin-conjugating enzyme</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_005047</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YF98"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23804">
        <property type="entry name" value="UBCc_UBE2S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000031">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="9">
        <location>
            <begin position="99"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="262"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="299"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="342"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1744514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="351" mass="37473" checksum="59794FB3E28C0C84" modified="2024-05-29" version="1">MEHSSSSSPEQQQQPPSATTAAATASRTTSSSTTATFAASATTTTSTSLFRSTSSIKPQHSTSSLFSSTRSLSSSTSSMGGSTTIAMGGGGCGENLPPRTLARVARDVRDLVKSPPEGVRLVVDEESGMPGSLAEIVAEIEGPEDTPYHTRYFQLKLVLSTDFPSKPPRGYFLTKIYHPNVDPTTGAICVNTLKKDWTPTTSLSHVLTVIRCLMIVPFPESSLNDEAGKNFMDSYDEYAKRARLLAGVHGLTRWSSAPIMMNGAANMSGGEGKTPENDSDNEDMTKKKQQHHHLDGKKSPTTLPNNAVDNSGSSPGKKLKKSSHHSNIVRASGNGGKSLDKKSKKKSLKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFP5</accession>
    <name>A0AAD8YFP5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004673</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFP5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="176" mass="20244" checksum="317A32F6EB3B4F80" modified="2024-05-29" version="1">MRARLYKAEAYEAKIRIASQEQSLSTLKQELEELRFFAAVEQGAAMENNSTISSNHNDPPPKEDEDMMDVKQKAAEKDAELIECLATELEETEKELKRTKRQLKEERSKNKSLNEGVETHSKLMIGKMQQELDAERAKNEALSEEMSLIATRRESNNEWQTKEAALNRTIENQQAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGF0</accession>
    <name>A0AAD8YGF0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_003967</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGF0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="75"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1744676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="261" mass="29579" checksum="536AAF721D316776" modified="2024-05-29" version="1">MSATTNDTSDPAARLQELIQKREEILRGGEIHSQLHQIKELVQKEEACVLEIERQRVDAIMKEYEEQHPLITEECPLCLEDIPMASNRSFVRFSCCGKGCCRDCNLKASIHKVKKCPMCRADIPTERKAIKQIKALAKKGVAFAQAEEGWKFLYGGNGYPLDVKQAVKFLELASEQKNPKAMRFLGHTLYEGKLVTRDVQRGLYLTHEAADLGNVESRLYLGKLYVLGNGHMRDIPKAIHNYTIAYDVNTTIKHKVGQHII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YH35</accession>
    <name>A0AAD8YH35_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003802</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YH35"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="156" mass="17998" checksum="90D375732F4DC6D7" modified="2024-05-29" version="1">MCRNRHNIHGVDASDELTVDSDSQASFPPMRTMTQPTVPTERPRKVIDTKNLNEQDLKNLKSSDPFLYYSIPFVRDAEVVNKEFQIPIQDGSQPSTNTKVERKSRISYECHPDLLLDGLLDDDLVGQECSLEHEDFAFDSILQLMMITNDERRQRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIL1</accession>
    <name>A0AAD8YIL1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Zf-MYND and TPR domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_002593</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIL1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="14"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="153"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1747249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="306" mass="34482" checksum="FA2DC6421498424F" modified="2024-05-29" version="1">MSDVEIGMMYVMCCASCGTEEVDHIKLKKCNACYLVKYCSVKCQKEHRPKHKRECKKRAAELRDEILFKQPESSHLGDCPICCLPLAPSIDEKASPMMACCSKIICNGCNIANQIREVKGKLLLKCPYCRHQLPKSQEEAAQIRMKRVEVNDPVAIWRLGVRCRREGDYESAFQHYKKAAELGNADAHYNVSCVYRDGEGVEKDKKKEVYHLEEAAIAGHTFARHNLACYEGINGRHERAAKHWIINAKLGDQKSMEGLKEGYPDGLVSKEDFAAALRAYQAALDATKSPQRDKAAEYEIFKSTSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIQ1</accession>
    <name>A0AAD8YIQ1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Superoxide dismutase [Fe]</fullName>
            <ecNumber evidence="3">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_001272</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIQ1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016872">
        <property type="term" value="F:intramolecular lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="entry name" value="Iron/manganese superoxide dismutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016087">
        <property type="entry name" value="Chalcone_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016088">
        <property type="entry name" value="Chalcone_isomerase_3-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036298">
        <property type="entry name" value="Chalcone_isomerase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42769">
        <property type="entry name" value="SUPEROXIDE DISMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42769:SF3">
        <property type="entry name" value="SUPEROXIDE DISMUTASE [FE] 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16036">
        <property type="entry name" value="Chalcone_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54626">
        <property type="entry name" value="Chalcone isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chalcone isomerase" evidence="10">
        <location>
            <begin position="104"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Manganese/iron superoxide dismutase N-terminal" evidence="8">
        <location>
            <begin position="303"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="Manganese/iron superoxide dismutase C-terminal" evidence="9">
        <location>
            <begin position="396"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1747309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="545" mass="59336" checksum="926936F952240933" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIV7</accession>
    <name>A0AAD8YIV7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002152</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIV7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00267">
        <property type="entry name" value="ABC_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32114">
        <property type="entry name" value="ABC TRANSPORTER ABCH.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32114:SF2">
        <property type="entry name" value="ABC TRANSPORTER ABCH.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad50/SbcC-type AAA" evidence="2">
        <location>
            <begin position="21"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="367"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="486"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="700" mass="77393" checksum="A6D4B50F97D8D778" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJF8</accession>
    <name>A0AAD8YJF8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002888</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJF8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="38"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="216" mass="25290" checksum="C8FA7C1CDCCF2CFD" modified="2024-05-29" version="1">MISKSRTKWYLIECLSAMHLYHRNDYDLRSEWEEKLEHTCYNCGRQFMKNKSRFLHLPKHMHRCPGCESYFDHNSSADGVAKDMDHRSGRSGRKKGFWLSVPLLIRSIASSRKKKEHQSARSGHTTIATVNCSTDKIESDRQNDAQVDGLIRHRKEQLNDDVIVDNSSCLADRDPCPFAFTYVTETVEPYQMHETDDESETHEVETYQLEWLLFNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJM5</accession>
    <name>A0AAD8YJM5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJM5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="47"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="428"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="117"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="490"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="53"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="429"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="659" mass="75120" checksum="3EE125D09D535397" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YK52</accession>
    <name>A0AAD8YK52_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Zinc finger CHCC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YK52"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.40:FF:000001">
        <property type="entry name" value="NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.40">
        <property type="entry name" value="q5lls5 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019401">
        <property type="entry name" value="Znf_CHCC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13156:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13156">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-A SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10276">
        <property type="entry name" value="zf-CHCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zinc finger CHCC-type" evidence="1">
        <location>
            <begin position="83"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="127" mass="13657" checksum="04A4F85DAEA3DAD7" modified="2024-05-29" version="1">MTMKAIQLLRQAALRTHARPSFTASSCRALSSVIPEAPQSAMDGSDKSLNRLERTESQYKLGKHRSNALELIEKVPPIEVEGDMAICDGGGGALGHPLEYIKVGYRGGKPVSCVYCGLKYVQKAGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKR1</accession>
    <name>A0AAD8YKR1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">5'-3' exonuclease</fullName>
            <ecNumber evidence="6">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_001895</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKR1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008409">
        <property type="term" value="F:5'-3' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033567">
        <property type="term" value="P:DNA replication, Okazaki fragment processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09898">
        <property type="entry name" value="H3TH_53EXO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09859">
        <property type="entry name" value="PIN_53EXO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000003">
        <property type="entry name" value="DNA polymerase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.10">
        <property type="entry name" value="Taq DNA Polymerase, Chain T, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020046">
        <property type="entry name" value="5-3_exonucl_a-hlix_arch_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002421">
        <property type="entry name" value="5-3_exonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001098">
        <property type="entry name" value="DNA-dir_DNA_pol_A_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020045">
        <property type="entry name" value="DNA_polI_H3TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038969">
        <property type="entry name" value="FEN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42646:SF2">
        <property type="entry name" value="5'-3' EXONUCLEASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42646">
        <property type="entry name" value="FLAP ENDONUCLEASE XNI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01367">
        <property type="entry name" value="5_3_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02739">
        <property type="entry name" value="5_3_exonuc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00476">
        <property type="entry name" value="DNA_pol_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00475">
        <property type="entry name" value="53EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="5'-3' exonuclease" evidence="5">
        <location>
            <begin position="538"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="98"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="152"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="226"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="298"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="471"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="114"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="197"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="227"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="242"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="332"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="473"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1747932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="861" mass="96336" checksum="E9DE0EF7C9EC70B2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YML1</accession>
    <name>A0AAD8YML1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_001864</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2160.10:FF:000002">
        <property type="entry name" value="Putative Ubiquitin-protein ligase E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2410.10:FF:000011">
        <property type="entry name" value="Putative Ubiquitin-protein ligase E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044611">
        <property type="entry name" value="E3A/B/C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700:SF2">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="7">
        <location>
            <begin position="971"/>
            <end position="1334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="505"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="853"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="16"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="510"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="526"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="5">
        <location>
            <position position="1302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1747901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1334" mass="148682" checksum="7EE4116B5476EE7A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMU5</accession>
    <name>A0AAD8YMU5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Tim44-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_000861</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tim44 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMU5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.240">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039544">
        <property type="entry name" value="Tim44-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007379">
        <property type="entry name" value="Tim44-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10721">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10721:SF1">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04280">
        <property type="entry name" value="Tim44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00978">
        <property type="entry name" value="Tim44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Tim44-like" evidence="8">
        <location>
            <begin position="259"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="376"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="386"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1748922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="454" mass="51551" checksum="3929386988C84032" modified="2024-05-29" version="1">MLRISLLRLESSISRPSATLPKSLVASYSSFRSVPSQKTDQRCRLLQRQQLSLIHEGIGTRTFSDNSDDGKKKKDLRVTIEKLKGVKSDTSDESTSADTNSDANKEHLDKFASMASSFVDTISETWNELVASGQAKDINKKIGTPSDGEQPNYANDDEAADKYEEYKGSKDIMLIDPEEHLSAWERMEKRLRDAPIIADILEKSGKVYEKSGAQERVQQTQQKIKHLKEDAEEAWETSQNPWVYRASSVYDTLTAESEFAAATRHLQKLDPDFTMENWKRDVMEHTLPNIMKLFLEGRVQELKPWLGEAVYNRLAAEARARKSEGVQIDTNVLAIMNGEIMACEMGGSTNVDKGDDPLILFHFMCQQIHCVRKKVKDEKKANSEDSNADSEGDKDESDEKTYMERELGEIVEGSEDDIRANSYVVAFQRQYDEEQMSLNWKIVDLRYNGAIAYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YN45</accession>
    <name>A0AAD8YN45_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">phosphoribosylaminoimidazole carboxylase</fullName>
            <ecNumber evidence="2">4.1.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_001041</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (carboxylase route): step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.21" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YN45"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004638">
        <property type="term" value="F:phosphoribosylaminoimidazole carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039476">
        <property type="entry name" value="P2CMN_synthase_LarB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000031">
        <property type="entry name" value="PurE_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF033503">
        <property type="entry name" value="LarB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43064">
        <property type="entry name" value="PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43064:SF1">
        <property type="entry name" value="SLL1489 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00731">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01001">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52255">
        <property type="entry name" value="N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PurE" evidence="3">
        <location>
            <begin position="178"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1749102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="308" mass="32693" checksum="9DEA3FA838826D11" modified="2024-05-29" version="1">MPLYRRSLCQLGRECSRHSLIQSRFVTRKPLLPFRLCQHRHISCSGTKLNSQSPDEILSAFANLDHSRVKRAGFPEAVFGQGKTPSQIHLILDSMANNVNEMIDAASESDGIVNSASTAIIATRIDKSVYDEVLEIGPLKYGIMQYHETAKILSVRANALNDVNGNERTDLQFSTTQKSVVVACAGTTDLPVAEEAALTLSLSGIQVTRVYDCGVAGLHRILTALPKLRDPSVGCVLVCAGMDGALPSVVGGLVDVPVVAIPTSVGYGVSLGGISALLTMLNSCSPGVGVVNVDNGFGGAVWAMKCLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YN82</accession>
    <name>A0AAD8YN82_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001057</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YN82"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1749118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="258" mass="27858" checksum="E60C3867D0B34105" modified="2024-05-29" version="1">MNAVGSPHAVAAAAAAAASQSSPQRKRKHEAPADYLERPIKWGKSSRDVTCTQEQFEAMLQKSYGPRINNDGIRKSGKDKHGHTLYYDRGLVRCQACNNKRVVYGAIVQHIVGEGHCKRVAKIYKDKESITYSKLELQEKQDADAEGNEAVASDETTGQVIVPALPDYDNMLQAAAGGGKKSPTKRKAPKKNAGKKKATATDDDDSQIALTVQGGLVVNGLDIVKYIRGLEGRISELEMKLAAATSTEVPLTENPTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YNI3</accession>
    <name>A0AAD8YNI3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_001222</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YNI3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002935">
        <property type="entry name" value="SAM_O-MeTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01596">
        <property type="entry name" value="Methyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1749283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="259" mass="28755" checksum="BB4518C43D3B4E30" modified="2024-05-29" version="1">MGSAPTSSANGTVASRNPYFNFSMSAVIQRFSFYYCKAKSYIYDALILTMTEAWYRAVLEKLPDGSNLLDVGIGTGGALLRCTDLLVKKDLKVVGIDIDAAYVEAGHEAILYAGMDDRISINVVNVYEAKEKVMELVKQMGGSEDSDGRFVDAVYFSGSFSLLPDPVKALHLVSEFVKTKDGEKGSIFITQTYQRKTPFFLPYMKPLLKYATTIDFGQLVTEEDILRTFEESRLEVVQHEVIPGSVDNSLQAAYLSILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YNN9</accession>
    <name>A0AAD8YNN9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Pre-mRNA-splicing factor RBM22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_000579</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YNN9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071006">
        <property type="term" value="C:U2-type catalytic step 1 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071007">
        <property type="term" value="C:U2-type catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036002">
        <property type="term" value="F:pre-mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039171">
        <property type="entry name" value="Cwc2/Slt11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048995">
        <property type="entry name" value="STL11/RBM22-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032297">
        <property type="entry name" value="Torus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR RBM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089:SF6">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR RBM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21369">
        <property type="entry name" value="STL11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16131">
        <property type="entry name" value="Torus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="9">
        <location>
            <begin position="161"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="243"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="161"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="181"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="345"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="355"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1748640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="408" mass="44735" checksum="0B0D81F33BE9C2C6" modified="2024-05-29" version="1">MASIKKDDNKQKWEETEFPLVCETCLGDNPYVRMTKETHGKKCKICDIPFTVFAWQAGTRGRLKKVEICRTCARSKNVCQVCIYDLQYGLPVQVRDKILAEEGCKDAVVAVPQSDANRAWMTAQQERDIEQGKAIQGCVPTNSAAAMKLQSMARMEPRYERNLPKLCSFFAKGECNRGSQCPFRHELPRDKNDPLSKQNTKDRFFGTNDPVASGMVRRQKEKAEKRRAELKARGGDGDERAVSTLYVRFTDEGSQKRITEAEVRDKFYSFGEIASVRMHADKGAFVEFTSPQATQHAIANTNRSNIGGRKVIVNWARVPKRGAVSAGPQSQPGVAGEGGRIRPMAPPGGFKGKNSAASAGFSTSLGVPRPGGGVIRRPGVSGARGAAPKPYYPSTDPGRLGSQSSPQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPS0</accession>
    <name>A0AAD8YPS0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF1336 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001208</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPS0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009769">
        <property type="entry name" value="EDR2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31558">
        <property type="entry name" value="CW14 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31558:SF3">
        <property type="entry name" value="CW14 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07059">
        <property type="entry name" value="EDR2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="363"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="300"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1749269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="991" mass="108368" checksum="C03686BEBED31CAE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPX8</accession>
    <name>A0AAD8YPX8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nuclear segregation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001181</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPX8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042175">
        <property type="term" value="C:nuclear outer membrane-endoplasmic reticulum membrane network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008298">
        <property type="term" value="P:intracellular mRNA localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039604">
        <property type="entry name" value="Bfr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31027:SF2">
        <property type="entry name" value="LEBERCILIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31027">
        <property type="entry name" value="NUCLEAR SEGREGATION PROTEIN BFR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="307"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="30"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="327"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="363"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1749242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="374" mass="42204" checksum="4A04CE85C5764952" modified="2024-05-29" version="1">MKFTNLADIEKEIARLQRKQETSSMSLSDEKKLIKDIEALQASRRTAEELKSKQGDLDTIKDDRKVIQADLNAKDKEIDSIQKEIDAQSKILKDLVDKQSSQRGTVDELMKQRDALKSDIDDKFKEKNTLRTEFREKTNDWYHNQRAIKAQRQMQYEEEKKRREEEKAAYLKKKEEEELAKTPYEEEMALCEYLADYLTKTYLTDSQEEEAKKAKEAEEKAKADVVAVKDDPFAGFKAFSKKPEDEVNYFGKGKGIKKLKAKKSSKAPTFSLSLDLFDQFGLITLNPPTSLDGVAASVEELKAKKQWYSEQPRGSVPTAKDIRKANAEAAAKAQSKGAKAGNKGKKGNFSISNEDFAPLGTGAVSSGTGENWLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3U1</accession>
    <name>A0AAD9D3U1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3U1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="490" mass="56844" checksum="A809C8182DDB0E25" modified="2024-05-29" version="1">MRKTLLGGTKQQSKQQTVQKSMEGPLPYVEANTKISRVLKHMKLKTNKEDMQASRLDEFYKLVARETAAAIVLQSSCRRVLATACVRQLALETAQATKIQCFVRRFIARRVPQTEANQIGTQRSDNLPIHRENALAKPLVGSKPNPMEDALLASRICRYADQLLCKTNSMHRQTKTCSKRVASMHAEHSKAALKIQCCWRRFDAQLRNRALLYERSVEQHCNKIRIITSEHNYWTQKIHALETHFEDQFNLLQQISPQEVEGGWEEQVKLNLTDTRERITKAKLDMLFRIQVKLKSVESKLNDILSNEKGAADSMNHWGKWRQAEQDALWNFQRQHDDKVAEKEKRKSIVDEQLRWAVKFYVASGKPDKRRPLVVDDSDSVNIRIEELTAAAALQMNKIQEMNHLSRTWTPFQRMMDQFNQGTIFEGLTQNGDTRQYSHEEMVHPTLISQSKSYMARAKLEPFPQKIPWHLLKELETSKKRLNVSLTSIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D479</accession>
    <name>A0AAD9D479_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GST N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_016900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000067">
        <property type="protein sequence ID" value="KAK1732419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D479"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007494">
        <property type="entry name" value="Glutaredoxin2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04399">
        <property type="entry name" value="Glutaredoxin2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042271984" description="GST N-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="GST N-terminal" evidence="3">
        <location>
            <begin position="66"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Glutaredoxin 2 C-terminal" evidence="2">
        <location>
            <begin position="225"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1732419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="308" mass="33995" checksum="FA4E9F0383F2DBFC" modified="2024-05-29" version="1">MKVSLVSLAALLGVAAGFSAAPSSIGNTRSVATTSLTSVQLSSTQVDAAPFAKPPRVVREQLPTVYVYDHCPFCVRVRLAMGVKNVKHLIHFLANDDIASPTALVGKKIAPIFELPEDNFVMGESLDIIAKIDTDPRFGPTNQILPASGRKDIKAWQKSVQTLLRTLQRPRYVATGLLPEFQQIDGRHAFIKNHQLPPYEKPEWKGDGTQENPGMDMDVKLKLYAEAMAADPTPLVEDLNARLVELDDMLYSEHYCSEGGFSLDDVDLWARLRSITIVSGVQWPTKLRSYMDNLSALGDVPLYDEMAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4A6</accession>
    <name>A0AAD9D4A6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_016750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000064">
        <property type="protein sequence ID" value="KAK1732538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4A6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1732538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="62" mass="6938" checksum="58423AD9F8D78BE5" modified="2024-05-29" version="1">MELWLSDTCSQFVLSQLTEAEFGGGLETIEDGAFVGCQSSLRRIAIPLQDDLNVYTEQQRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D553</accession>
    <name>A0AAD9D553_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ubiquitin-conjugating enzyme E2</fullName>
            <ecNumber evidence="9">2.3.2.23</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_015190</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D553"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd14314">
        <property type="entry name" value="UBA_II_E2_pyUCE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23800">
        <property type="entry name" value="UBCc_UBE2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="8">
        <location>
            <begin position="2"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="7">
        <location>
            <begin position="163"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="5">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1734187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="203" mass="22299" checksum="9D4C6B9B0843BA5A" modified="2024-05-29" version="1">MAANGRVKKEISIICKTDPTSGVIATTAGDDLSIPGKPGWRHLIGTIQGPSGTPYENGVFDVDILIDGEYPFAPPKMKFITKIWHPNVSSATGAICLDILKDQWTPALTIKTAMMSLQALLCSPEPNDPQDAQVAKMYLENKPEFDRTAKFWVEQYASPKSDTSKEDAVGRVCEMGFDKESARKALEKHKWDEQAAVNDLLGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5K8</accession>
    <name>A0AAD9D5K8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Integrase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_015610</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000045">
        <property type="protein sequence ID" value="KAK1733755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5K8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039537">
        <property type="entry name" value="Retrotran_Ty1/copia-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42648">
        <property type="entry name" value="TRANSPOSASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42648:SF11">
        <property type="entry name" value="TRANSPOSON TY4-P GAG-POL POLYPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0229">DNA integration</keyword>
    <keyword evidence="9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="8" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="12">
        <location>
            <begin position="236"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="582"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="2"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="227"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="590"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1733755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="611" mass="69375" checksum="9BF51E9CF8F6C3CE" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5M8</accession>
    <name>A0AAD9D5M8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2'-phosphotransferase</fullName>
            <ecNumber evidence="3">2.7.1.160</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_015512</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2'-phospho-[ligated tRNA] + NAD(+) = mature tRNA + ADP-alpha-D-ribose 1'',2''-cyclic phosphate + nicotinamide</text>
            <dbReference type="Rhea" id="RHEA:23324"/>
            <dbReference type="Rhea" id="RHEA-COMP:11106"/>
            <dbReference type="Rhea" id="RHEA-COMP:11107"/>
            <dbReference type="ChEBI" id="CHEBI:17154"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:76596"/>
            <dbReference type="ChEBI" id="CHEBI:82883"/>
            <dbReference type="ChEBI" id="CHEBI:85027"/>
            <dbReference type="EC" id="2.7.1.160"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KptA/TPT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.160" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000044">
        <property type="protein sequence ID" value="KAK1733815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5M8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000215">
        <property type="term" value="F:tRNA 2'-phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006388">
        <property type="term" value="P:tRNA splicing, via endonucleolytic cleavage and ligation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.170.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.970">
        <property type="entry name" value="RNA 2'-phosphotransferase, Tpt1/KptA family, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002745">
        <property type="entry name" value="Ptrans_KptA/Tpt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042081">
        <property type="entry name" value="RNA_2'-PTrans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042080">
        <property type="entry name" value="RNA_2'-PTrans_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12684">
        <property type="entry name" value="PUTATIVE PHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12684:SF2">
        <property type="entry name" value="TRNA 2'-PHOSPHOTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01885">
        <property type="entry name" value="PTS_2-RNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1733815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="253" mass="28343" checksum="035C898A8520E805" modified="2024-05-29" version="1">MTTIIRNQDVTLSKALSYVLRHAAPSLGLEPSPDGYVPVEDILSLSHPKFRDKQSGRQRYTVDDVIRVVEMNEKRRFKLEYKSALDDGYVEGTVQSISAERNKKLLCIRANQGHSFKAGLQSNKLLMPLDAGELNSSELIIVHGTTQRAWELIRIEGLRRMKRNHIHFATGLPNENGQKSPISGMRSSSEIYIYISGKKCAEDAIPFYRSDNGVILTAGVDEGGLLPIKYFDKVVQASSGNVIWKHGQDWEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6M4</accession>
    <name>A0AAD9D6M4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">DDE superfamily endonuclease</fullName>
            <ecNumber evidence="11">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_013558</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HARBI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="11"/>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6M4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045249">
        <property type="entry name" value="HARBI1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027806">
        <property type="entry name" value="HARBI1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22930:SF85">
        <property type="entry name" value="GH03217P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13359">
        <property type="entry name" value="DDE_Tnp_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042162834" evidence="9">
        <location>
            <begin position="42"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="domain" description="DDE Tnp4" evidence="10">
        <location>
            <begin position="301"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="509"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1735852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="574" mass="66715" checksum="16E3A509F62B25BC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6N8</accession>
    <name>A0AAD9D6N8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Putative GTP diphosphokinase RSH1, chloroplastic</fullName>
            <ecNumber evidence="2">2.7.6.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">RelA/SpoT homolog 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">ppGpp synthetase RSH1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_014325</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Purine metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RelA/SpoT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.5" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6N8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008728">
        <property type="term" value="F:GTP diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015969">
        <property type="term" value="P:guanosine tetraphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04876">
        <property type="entry name" value="ACT_RelA-SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05399">
        <property type="entry name" value="NT_Rel-Spo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01668">
        <property type="entry name" value="TGS_RSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000002">
        <property type="entry name" value="GTP pyrophosphokinase (RelA/SpoT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3210.10:FF:000001">
        <property type="entry name" value="GTP pyrophosphokinase RelA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.460.10:FF:000001">
        <property type="entry name" value="GTP pyrophosphokinase RelA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004811">
        <property type="entry name" value="RelA/Spo_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045600">
        <property type="entry name" value="RelA/SpoT_AH_RIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007685">
        <property type="entry name" value="RelA_SpoT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033655">
        <property type="entry name" value="TGS_RelA/SpoT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00691">
        <property type="entry name" value="spoT_relA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21262:SF31">
        <property type="entry name" value="GTP PYROPHOSPHOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21262">
        <property type="entry name" value="GUANOSINE-3',5'-BIS DIPHOSPHATE 3'-PYROPHOSPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13291">
        <property type="entry name" value="ACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13328">
        <property type="entry name" value="HD_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19296">
        <property type="entry name" value="RelA_AH_RIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04607">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00954">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="9">
        <location>
            <begin position="265"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="10">
        <location>
            <begin position="610"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="8">
        <location>
            <begin position="885"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="45"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="781"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="46"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="75"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="781"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="795"/>
            <end position="805"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00070102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00075768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00082153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1734865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="957" mass="106782" checksum="855973CC29391832" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D726</accession>
    <name>A0AAD9D726_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014259</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D726"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1735193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="465" mass="51974" checksum="4D9ADA1C8A1C57E3" modified="2024-05-29" version="1">MAAHKSSNGKIHKKNCKPSSLDTTKMDLDHCTKALKSALYGGSPDLYFIIKRVRELFDNGAENSDMAAFHLHSIARGLMSLNTPLLLGIVACPYMSSLLFGEEEDLLSTKYRLVKNTKLAKYNGRPSDEFLEDIEDETEKEEVTLLVERYDKLDDSWGQPSSMSFCYLYFNLIVACTIRGQLSHSSTHDGNGTLRGGNPKMKSPETLLSTAALRRAMELWTDPHVLASCGDAMAPAASLAVTAVEYYQVHNLLCEEHLCNAHELVPGLAIDHLAMTCMKEILDGAGSASYSSKLLKSLKDICGKVWDANCPWRNLPIERRATFAIAFYDYVENADNNSFSSYGRGVELPDNDDMNQIFRTIVGLHNPIDATIAGSVWKTAAEDGEFIGVHGSGCNYRSRAFFYYLLRSESDGWEGMDVTKLIKEFEDIPRIHKAPDDPKVKEKDECFRLAEGDKRHDEMNRIFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D797</accession>
    <name>A0AAD9D797_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase (GlcNAc)</fullName>
            <ecNumber evidence="3">2.4.1.229</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012579</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.229" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D797"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033830">
        <property type="term" value="F:Skp1-protein-hydroxyproline N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021067">
        <property type="entry name" value="Glycosyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34496">
        <property type="entry name" value="GLCNAC TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34496:SF6">
        <property type="entry name" value="GLYCOSYLTRANSFERASE 2-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11397">
        <property type="entry name" value="GlcNAc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="632" mass="70591" checksum="73C31E17B12EC565" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7G3</accession>
    <name>A0AAD9D7G3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoinositide-specific phospholipase C domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013746</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7G3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051057">
        <property type="entry name" value="PI-PLC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593:SF140">
        <property type="entry name" value="PLC-LIKE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26178">
        <property type="entry name" value="PI-PLC_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="460" mass="51457" checksum="C9FF6A79F2EC0102" modified="2024-05-29" version="1">MYDMNSIGSGVHERTPISARAAAASLQQPRSHFKQTPSNTRRQQQQDNASIQNASQNSTHSDDELGRLVSPPKKNRCTLPVASFSLVVVAVALIVTWQVFPTEEIVVKFLPKFEAPASPYMGEEAPGTATSDSDQNNGDGGIDIDIPLENEVPISDATSVPSFMKCPIDSDELCCNGSPQNCELKVNETMFATLHNAMSTEEGDFTFGFNHYKTLEKAMVAGYRGINLDVCNCNGKLQFCHNVCDYGERVPQEVFTNVVNFLKEYPSEVIILIFQATTEKGPIVWNDLYDEMKQVEDFEDMLYVHQGEGQEWPLMGDLVKSNKRIVTFYFNGGTCTDDICPEPFLPFFKYTAETEYQSANLDELRNIQYSCQLTRGPGGFKGDFFAVNNFVTPPDPEASAITNTQKFLSERLTSCANFNGKRPNFVYVDFWGEGVTSQLVQYANKQMASQKEKEEQKERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8S7</accession>
    <name>A0AAD9D8S7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RanBD1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8S7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000156">
        <property type="entry name" value="Ran_bind_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045255">
        <property type="entry name" value="RanBP1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23138:SF87">
        <property type="entry name" value="E3 SUMO-PROTEIN LIGASE RANBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23138">
        <property type="entry name" value="RAN BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00638">
        <property type="entry name" value="Ran_BP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50196">
        <property type="entry name" value="RANBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RanBD1" evidence="2">
        <location>
            <begin position="87"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="249" mass="27961" checksum="FEC37452A9B18FA3" modified="2024-05-29" version="1">MEYIIPCRGKRRRIVCSDDGVKEEANPTNQTATDEQSSRNRAESVASTAATNPESDTDEDEDPLAEEANQLQNEIILKKLQRANGEGDEVQLLHTSSRAKLFEYVKGNDGNDDEGAWSYRGEGQVKFIRCLEEGYNRGMIRMELTKNCTLEVLMCHECTHEDAMAMNSNRGKAYTWICKDWAYNTTKKTFAIRFDDSMQALEWKQMFEQSKINNCNVRRGVGVPDAAAVDDVTSTFKSLSTATAASPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8Y1</accession>
    <name>A0AAD9D8Y1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Guanine nucleotide exchange factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_012072</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00171">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1000.11:FF:000002">
        <property type="entry name" value="Cytohesin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
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        <property type="entry name" value="DCB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015403">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HDS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032691">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HUS"/>
    </dbReference>
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        <property type="entry name" value="Sec7/BIG1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
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    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
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    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF375">
        <property type="entry name" value="LD29171P"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF16213">
        <property type="entry name" value="DCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09324">
        <property type="entry name" value="Sec7-like_HDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12783">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SEC7" evidence="8">
        <location>
            <begin position="841"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="347"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
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            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
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            <end position="829"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1087"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1511"/>
            <end position="1530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1690"/>
            <end position="1710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="117"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="155"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="167"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
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            <end position="241"/>
        </location>
    </feature>
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        <location>
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            <end position="253"/>
        </location>
    </feature>
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        <location>
            <begin position="357"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="477"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="798"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
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        </location>
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    </feature>
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        </location>
    </feature>
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    </feature>
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        <location>
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            <end position="1704"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1737205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2187" mass="240165" checksum="AE51F82AE2F420D6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9T8</accession>
    <name>A0AAD9D9T8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polygalacturonase</fullName>
            <ecNumber evidence="2">3.2.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011249</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="protein sequence ID" value="KAK1737955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9T8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051801">
        <property type="entry name" value="GH28_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31339">
        <property type="entry name" value="PECTIN LYASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="352" mass="38779" checksum="E09BAF791B236C44" modified="2024-05-29" version="1">MGKSSLNNGRNNTQATKKRRISLTCVFALIAVTYSLFIYFVIVGFDGGKKETVVVGFDNGGGKENDGSAPLKLRPRNNAQDNMKAQSQQSQPISPNTPDDFCGSCKFRDTDFSCTERIDWVIKNKKITMKEAIMENLKYCLKEGVQYVETDNSKTSSSLGGKNNVEVAMSTSTPIYWIMVDVTEYGAIGDNNTDNTDAFHAAIEELNKAGGGELLVPSGGVYQTAPITLGPHTTLTVHGTIRGVADQHKFPAIDPLPSFGRDADFRVKRRRQALVSARHAPNITIRGDGVIDGAGWYWYPFFLNHTAANYLGRPHIIEIENCTGVEITGVTLRDPAFWTLHPVYCTDVYIHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DA72</accession>
    <name>A0AAD9DA72_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Protein transport protein SEC31-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_009601</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat SEC31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DA72"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090110">
        <property type="term" value="P:COPII-coated vesicle cargo loading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007029">
        <property type="term" value="P:endoplasmic reticulum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.940.10">
        <property type="entry name" value="Functional domain of the splicing factor Prp18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024298">
        <property type="entry name" value="Sec16_Sec23-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040251">
        <property type="entry name" value="SEC31-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13923">
        <property type="entry name" value="SEC31-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13923:SF11">
        <property type="entry name" value="SECRETORY 31, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12931">
        <property type="entry name" value="TPR_Sec16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4 9" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="192"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="259"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="11">
        <location>
            <begin position="790"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="742"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="766"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="742"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="772"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="801"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="838"/>
            <end position="852"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1739842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1045" mass="113729" checksum="431CCAF89712899E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAF4</accession>
    <name>A0AAD9DAF4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Bestrophin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_010630</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAF4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044669">
        <property type="entry name" value="YneE/VCCN1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281">
        <property type="entry name" value="UPF0187 PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281:SF19">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION CHANNEL-FORMING PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25539">
        <property type="entry name" value="Bestrophin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="406"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1738600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="445" mass="49620" checksum="146719AFE084FD4E" modified="2024-05-29" version="1">MTGNNNSVDDDTMIQPGLGLHRRPTQQDNLRTSLRHGHGISLVHVNPMIAGHNASLITPDASDTSHYSFSSALIYQASTKEDEIFRKHVSSFSYRVICNGPFLFAIASYIAVTAIILNVPVLRESTFMDWLSKSDSGMAFFSAWEGRCLWGTLIFAAINLAQQGQGSFTEKENFRRLCALIVCFSIACKNQLYGQSIEADGDYLLTRGLISKTEYEQVIKRQGWQPYYFLGALREIIDVDLKMSGQRAKINNDVYSFKGSTTDAQLLMMDGALGQMASIIGDLIRVKATGLPMGYDSIFYFIYLVYFVVTTLSWAIKLQWYTPILMSLLHLVVRCITELGTCLEDPFGNDITDLPLDKFCRAIEAQIAAVFTDTFPESTEYVSAWPTRRATASNSTTTRPTTCLSVEEPVTPTDDDFEENYPQDKPTRQLSTILSGDALSGDDEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DB02</accession>
    <name>A0AAD9DB02_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008837</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DB02"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042146722" evidence="1">
        <location>
            <begin position="16"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="533" mass="60917" checksum="574CAA81DFB9D19E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBR0</accession>
    <name>A0AAD9DBR0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heterotrimeric G protein alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_007955</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBR0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000051">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF302">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-5 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0807">Transducer</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="46"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="174"/>
            <end position="180"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="199"/>
            <end position="203"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="268"/>
            <end position="271"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1741477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="357" mass="40568" checksum="53E0D53944992131" modified="2024-05-29" version="1">MGACLSTGSAEDLAAMKASKEIEKMMNQQFEMDNSKVKLLLLGAGESGKSTIFKQMRVLFGAPLTDDEKQQITPVVYNNTITSMKILCSEAKNLGYDADVVAKDKFDFMLTLDDQCDVNEDVGVAIKELWTDPGILLTWKRRSEYQIIESVKYYFNEIERIMKDNYVATQQDMLLARVRTSGIVTEKYVIDGVDFEMYDVGGQRNERKKWIHCFDDVTAVIFVAALSEYDQALFEDATTNRMVEAVDLFGDICNNKVFESSAMILFLNKKDLYEEKIKAVHIGDQPAFSNFSGNIGDSDYYDKGIQYFLDMFLAENQNPDRQIYSHATCATDSQNVEVVFNSCKDIIMRKNMEDMGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCJ9</accession>
    <name>A0AAD9DCJ9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Carbonyl reductase</fullName>
            <ecNumber evidence="5">1.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_008870</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCJ9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43963">
        <property type="entry name" value="CARBONYL REDUCTASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43963:SF6">
        <property type="entry name" value="CHAIN DEHYDROGENASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1740775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="335" mass="36849" checksum="C072617FACB80B68" modified="2024-05-29" version="1">MNLRRSFREAADKKLQSAKVSNTMASHILILLSMVLMVGRTCHAFATPSNKIALITGGNKGIGKEIARRIGTEPGFTAIIASRDVALGQKAADDLKESGEYECDVVALPVPLDLTDDKSIIAAAKHVEKEYGRLDVLINTAAICFNDPTLYGKVDHTPFQNQADITIRTNYFGTLKVTQECLPLLKQADSPRIINVASAAGRLTILRSQELVDKFTSNTLTEPQLSTLMEQFVNDVQNGTHEEKGWPNTCYGMSKLGIIALTKILARENEGMLINSVDPGYCKTDQNNNQGTVDPADGAYTPYLLALMEQDDEDDGEDMSGLHFYDQQEIPWSYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DED5</accession>
    <name>A0AAD9DED5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Silicon transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006666</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1743069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DED5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015708">
        <property type="term" value="P:silicic acid import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004693">
        <property type="entry name" value="Silicon_transpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03842">
        <property type="entry name" value="Silic_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="123"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="190"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="284"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="380"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="414"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="483"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="518" mass="56437" checksum="2BF4E10C835D6514" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEL2</accession>
    <name>A0AAD9DEL2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEL2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="338" mass="36942" checksum="161D8D7A3D4830B1" modified="2024-05-29" version="1">MTVKDYGSSSQSTQPTNVQVIAPATLNAGYTFDAVYEGNTFTVTVPDGGVVKGQRFIVPFIPTAEATIMEASLLPLNSPNTRGNGMGEDSIPTGVWRDALCDCCKFGPCHPSFLTACLCKPIIIAQLLTRMKMTWLAQRTRFRNTNTNLSDSRTEIDQRWKNTFRNIILVSVIFCVLVMVVVPAPQLDPTDPNAYDELSDAEKKAYFINSSINSSLSALLGFYFFYLMVQLRATLRHVYSIPEEKCLFLYCGGNPSDGICGSGDGNRLCSAGVPVGVEDVCCVLFCPLCTTSQMARHTVDYEYRSATCCNSVGVTKYMDDEAYEGIENGVGEGSVLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFH5</accession>
    <name>A0AAD9DFH5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Metalloendopeptidase OMA1</fullName>
            <ecNumber evidence="8">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_005310</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFH5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.10">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051156">
        <property type="entry name" value="Mito/Outer_Membr_Metalloprot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22726">
        <property type="entry name" value="METALLOENDOPEPTIDASE OMA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22726:SF1">
        <property type="entry name" value="METALLOENDOPEPTIDASE OMA1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M48" evidence="7">
        <location>
            <begin position="227"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1743713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="440" mass="50080" checksum="35ED3B0A883DDBC7" modified="2024-05-29" version="1">MAMVVQSFLLTRSTPKLAAIMYSKSALLSSSAPLLHRHCFRSCRSSLQRRTAQIHHRFSTTSSSPVNKSPVNKDKWRQIARIAYYIRIPVLTLSIYGIGYQQGIMDFAREKEIMEAKLLQTVLAGVGCTSPEDLDMVLIAHEGEDWRIVLSRLREKFQIFHSDDMERYKEHHHRMVMLRDVAKVGEKIIKVARSYVKSKLAEVVRDAVNQLPPEVQEDEKRLYEALEQIEEVALWTKATRHMEGDTWKFVLIPSVIPNAFVSEILPHRIFITTSMIETFIKSDDELALTLGHEVSHLILGHSSNRNSFEVFFRTAEILVLSLDPTEGLLSLAFMAFLASLRHAIGAEFSRNDEREADELGIKLCAMACFDTKSASHVFHRMHLADVESGKQAASNRAGLLSFFDSHPPSEERYHSLLEESGKKIGKIRGYNVCLVEDYFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFN6</accession>
    <name>A0AAD9DFN6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004997</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFN6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041917881" evidence="1">
        <location>
            <begin position="22"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="403" mass="44821" checksum="0830B625B8A52D29" modified="2024-05-29" version="1">MMMRAAVVPSSPLLLHLLTQARTITSFAPPVTIARPQICSSINRHVSTTSSLFDMMKNPTSCSSTAASTPLTSTTLGSVAAGGDHAGLSATFSSKTGELIPVPEHLVPESMIEWGEIPSYFEILVSEDLLEENEEKKTKMERTTITVLPEVGCGIDNLETTKKVEEFNLHTNESRHVKWKDGKEQDVLVLDRKVGPSTAPDQLVYVETMFQVASEVVTDDQDAAATDNEDREQVYPRRIRVTFTIDTTSNHIIKDTITINIERLYSTTSTKGTRWSGPQHNSGGLDARSVMNTIGKDIVYGDVFGVKRLKSGEDVWMMDDAVKRIVIEGTEDDDSIRLPQNILVQFHNKESSQSWGIELSHFDVSGSKMYRRSVLRAFDSSEDGFGSVTYREEEKTLENDYND</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFR7</accession>
    <name>A0AAD9DFR7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_002688</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFR7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042168963" evidence="3">
        <location>
            <begin position="21"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="268"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="335"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="268"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1746081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="420" mass="47228" checksum="13EA115621849A32" modified="2024-05-29" version="1">MKSIIFALVLFFPTAITTTGFQLALTSKIINLTRSRTQTPPSTTEVVAVAPPSKPDSNNNKRSIIALATTSSSLLSIIHRPNVACATTATTIIPPSPLSSVSLIDPAILTTTEGLSVINSNNNKNLLSVLMTTFMSTIQMKQHSMAMFAIAVGMTAVLLKCAEGGYVKFVEFVAEQCLGYYGMNSVGGLRRHKRGVVVDEEETKKKKKKVDWNDYVLRLSRRRKEGAVDDDDKIVLDNKTMLFQQPAAKVAKDRYDNIMMERANQSYREKQYEQHHHDTDLSSTTSASDDLDTPSRSSWNKYKTTLDTLTQNQVEHDETSDKLQIMKNLLTWEDYKHLVSELQLKKEECSMLQEEVSSLKKLLQVERTVHSYHTPQVVVDSGSSDDDKELELKTLEDKAKEYDETIQQAKVKDGDSVRWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFT8</accession>
    <name>A0AAD9DFT8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF2256 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003496</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFT8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017136">
        <property type="entry name" value="UCP037205"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37463:SF1">
        <property type="entry name" value="DUF2256 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37463">
        <property type="entry name" value="GSL3115 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10013">
        <property type="entry name" value="DUF2256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042149665" description="DUF2256 domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="120" mass="13461" checksum="8DCC17FA781CBFDD" modified="2024-05-29" version="1">MKRQVHRLQLIAAAWLLASSSSLIGRSCSSFILPSSTVAHSKIISAASSSTRITTRLFGRGRGGNDKKEKKPSKSNLPEKICVVCNRPFTWRKKWERSWDEVTCCSKSCNAKRRSMKDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGK9</accession>
    <name>A0AAD9DGK9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase</fullName>
            <ecNumber evidence="7">4.1.3.44</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_002310</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.44" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGK9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102521">
        <property type="term" value="F:tRNA-4-demethylwyosine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031591">
        <property type="term" value="P:wybutosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013917">
        <property type="entry name" value="tRNA_wybutosine-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034556">
        <property type="entry name" value="tRNA_wybutosine-synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13930">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13930:SF0">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE TYW1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08608">
        <property type="entry name" value="Wyosine_form"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA wybutosine-synthesis" evidence="6">
        <location>
            <begin position="558"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="245"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="683"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="262"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="310"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="693"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1746966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="770" mass="85579" checksum="566E637090C321E4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGN0</accession>
    <name>A0AAD9DGN0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGN0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="248" mass="27330" checksum="C1C90FAEC0F448F9" modified="2024-05-29" version="1">MNKREKIGPSSTSKQKQIPPPPRKQSSVQTLKALGRMHMDTDDAASVSARSISSRRSRQPPPPPPVGRNTFSNPNPSSPSKKGSNTSIRSLSTKELSRLRKERHSSEGNNERIAELRAQQNSERDESAHIDLGRSLERIRAERKAAKDSLKERRKSGRSHNQKERFGESSQTFTLPMNDVRRGRATGARDDDILGAAAEIRARARRSLSRSKGREKAAEDVFGTRSVSGDDHTVDGDAVSVSSRGGDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHU9</accession>
    <name>A0AAD9DHU9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ataxin-10 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_001740</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHU9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051374">
        <property type="entry name" value="Ataxin-10/CTR86_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019156">
        <property type="entry name" value="Ataxin-10_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13255">
        <property type="entry name" value="ATAXIN-10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13255:SF0">
        <property type="entry name" value="ATAXIN-10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09759">
        <property type="entry name" value="Atx10homo_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ataxin-10" evidence="4">
        <location>
            <begin position="849"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="151"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="591"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1747777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="950" mass="103830" checksum="3B44A87984CDA309" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIM3</accession>
    <name>A0AAD9DIM3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methylmalonyl-CoA epimerase</fullName>
            <ecNumber evidence="4">5.1.99.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_001200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methylmalonyl-CoA epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.99.1" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIM3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004493">
        <property type="term" value="F:methylmalonyl-CoA epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046491">
        <property type="term" value="P:L-methylmalonyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07249">
        <property type="entry name" value="MMCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017515">
        <property type="entry name" value="MeMalonyl-CoA_epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051785">
        <property type="entry name" value="MMCE/EMCE_epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43048">
        <property type="entry name" value="METHYLMALONYL-COA EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43048:SF3">
        <property type="entry name" value="METHYLMALONYL-COA EPIMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13669">
        <property type="entry name" value="Glyoxalase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="3">
        <location>
            <begin position="73"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1749261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="219" mass="23819" checksum="FE50AE27D02E63CC" modified="2024-05-29" version="1">MVTSASFLSGVLFRLTSRAIRHQGRHQYKTCSTSTNHSIRYAPLPIASMRTSFPLRSLTSSTLQSSRPFKVLGLQQVAIGSLDKSALSNLWCNIFGVQQIGSYKSEKENVDEDILLLGKPGSPHSVEVDLMVPIDPEKSPKVNVPSLNHIGLWVDDLPEAVKWMERNGVRFTPGGIRKGAAGHDVTFIHPKGNEQSPIGGGGVLIELVQAPKEVIEALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIT1</accession>
    <name>A0AAD9DIT1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002447</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIT1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00136">
        <property type="entry name" value="PDZ_canonical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="134"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="303"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="468" mass="51139" checksum="64D9D1512B3532FC" modified="2024-05-29" version="1">MAIDKLPRRSIQERQQRTANRSPPPPPPFSQPMNAPSSPSNRTSSTRRNRRSSSRSSSPRTTVLGRANYQASAFAPPPFAALSLSNAPTSSHRNPPPPPPRRSSVGNVTAASSSSASGSRRAHQIIRMTLQRPMGIVFAPNEELGYGVRIIDLPQQGAAAMSQQLCVGDALVSVNDMDCTMSNSKEIMTLIGQAEGNVDLAFLRSSNAATSAEGEIDQESTQSIQVVNLKWQDISSGHKGRYSGAVNQHMRPHGYGKFTYDQGPSLEGEWDNGVLFELKAPAAAAADAAGAGNRRHIRRHSSKSSAASVHSQSQRNEGMSYATSIHPSSFRLSDYPNEMQQHQQLDGGQSREDSPVQYYCLGETIRSPQHMVQMASVEDTIQSVYTLQVSDFAFVMRSTGDWSFCQLIEREDNDAGEDIMTFCVNEVGHRKNLRPARWVKMVRSCSEGISVRPGGAFYGNDMDSEPSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DKV0</accession>
    <name>A0AAD9DKV0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">phosphopyruvate hydratase</fullName>
            <ecNumber evidence="5">4.2.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_001037</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the enolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DKV0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000015">
        <property type="term" value="C:phosphopyruvate hydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03313">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.10:FF:000001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.120:FF:000002">
        <property type="entry name" value="Enolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="entry name" value="Enolase-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="entry name" value="Enolase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020809">
        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01060">
        <property type="entry name" value="eno"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902:SF1">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03952">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00002">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00178">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01193">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="Enolase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="Enolase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="8 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enolase N-terminal" evidence="10">
        <location>
            <begin position="65"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Enolase C-terminal TIM barrel" evidence="9">
        <location>
            <begin position="203"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1749098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="497" mass="53574" checksum="35301D23F5D4CF6F" modified="2024-05-29" version="1" fragment="single">LKKRSTHSTLPHNCSTRSSLHTSYSTMVKYSAFTLAAIAIGQTYGFTAPNARNTRISTTLDMAKISSVKAREILDSRGNPTVEVELCTEDGKFVASVPSGASTGAYEACELRDGGSRYLGKGVLQAVGNVNDVLGPAVIGMDPADQRAVDDKMLEIDGTKNKNNMGANAILGVSLACSKAGAAANGIPLYAHYAKLAGNDNEKYTMPVPCFNVINGGSHAGNKLAFQEYFVIPTGAESFSEAMQIGCEVYHTLGKIIKAKFGGDATLIGDEGGFAPPCDNREGCELIMEALKKAGYEDKCTIGLDVAASEFRVKGEDKYDLDFKYDGDIISGDELGELYQSLAADYPIVTIEDPFDEDDWENWSKFTEKNREAFQVVGDDLTVTNIEKIGRAIDEKSCTCLLLKVNQIGSISESIDAVKKSKQAGWGVMTSHRSGETEDTYIADLAVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGAENTVYAGKNFRTTSWMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2LFD1</accession>
    <name>A0A7S2LFD1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004031</name>
        <name evidence="2" type="ORF">SMAR0320_LOCUS11255</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="HBGZ01015746">
        <property type="protein sequence ID" value="CAD9603713.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S2LFD1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CAD9603713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="131" mass="14427" checksum="75043664EBE7F9BE" modified="2021-06-02" version="1">MVSIKKKIKNALKKDSSKKSAAAAPEPSAPSPPTYDALMEARENDEANVCMPKDDIREEQGMVIVEDVTDMEEYLSVVEEVPTTQEQETQEEEEVTELVEPATPAEMKVVDEAPFKSSGFMCGITNCLGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1GXN0</accession>
    <name>A0A8K1GXN0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome b6-f complex subunit 6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cytochrome b6-f complex subunit PetL</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Cytochrome b6-f complex subunit VI</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 12" type="primary">petL</name>
        <name evidence="11" type="ORF">QTG54_017187</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="12"/>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2021" name="Front. Plant Sci." volume="0" first="0" last="0">
            <title>Chloroplast Genomes for Five Skeletonema Species: Comparative and Phylogenetic Analysis.</title>
            <authorList>
                <person name="Liu S."/>
                <person name="Xu Q."/>
                <person name="Liu K."/>
                <person name="Zhao Y."/>
                <person name="Chen N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CNS00100</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 10">Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9 10">The 4 large subunits of the cytochrome b6-f complex are cytochrome b6, subunit IV (17 kDa polypeptide, PetD), cytochrome f and the Rieske protein, while the 4 small subunits are PetG, PetL, PetM and PetN. The complex functions as a dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Plastid</location>
            <location evidence="10">Chloroplast thylakoid membrane</location>
            <topology evidence="10">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the PetL family.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MW679506">
        <property type="protein sequence ID" value="UAM91390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_010200900.1">
        <property type="nucleotide sequence ID" value="NC_058701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1GXN0"/>
    <dbReference type="GeneID" id="68638027"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009512">
        <property type="term" value="C:cytochrome b6f complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00433">
        <property type="entry name" value="Cytb6_f_PetL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007802">
        <property type="entry name" value="Cyt_b6/f_cplx_su6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05115">
        <property type="entry name" value="PetL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4 10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="12" id="KW-0934">Plastid</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1732144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="UAM91390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="31" mass="3406" checksum="AD6F838D4D37FCEB" modified="2022-08-03" version="1">MSILINYFLLVGFCFALAAGLYLGLKSIKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1H027</accession>
    <name>A0A8K1H027_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Large ribosomal subunit protein bL32c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">rpl32</name>
        <name evidence="7" type="ORF">QTG54_017177</name>
        <name evidence="8" type="ORF">QTG54_017256</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="9"/>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2021" name="Front. Plant Sci." volume="0" first="0" last="0">
            <title>Chloroplast Genomes for Five Skeletonema Species: Comparative and Phylogenetic Analysis.</title>
            <authorList>
                <person name="Liu S."/>
                <person name="Xu Q."/>
                <person name="Liu K."/>
                <person name="Zhao Y."/>
                <person name="Chen N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CNS00100</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Plastid</location>
            <location evidence="5">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL32 family.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MW679506">
        <property type="protein sequence ID" value="UAM91327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MW679506">
        <property type="protein sequence ID" value="UAM91383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_010200828.1">
        <property type="nucleotide sequence ID" value="NC_058701.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_010200890.1">
        <property type="nucleotide sequence ID" value="NC_058701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1H027"/>
    <dbReference type="GeneID" id="68637945"/>
    <dbReference type="GeneID" id="68638013"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00340">
        <property type="entry name" value="Ribosomal_bL32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002677">
        <property type="entry name" value="Ribosomal_bL32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044958">
        <property type="entry name" value="Ribosomal_bL32_plant/cyanobact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01031">
        <property type="entry name" value="rpmF_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36083">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L32, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36083:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL32C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01783">
        <property type="entry name" value="Ribosomal_L32p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="9" id="KW-0934">Plastid</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1732134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1732213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UAM91383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="54" mass="6172" checksum="8E0CDEC940094203" modified="2022-08-03" version="1">MAVPKKRTSKSKKNSRKANWKRKAAKSAQKSLSLAKSILRGKTTSFVYRLYVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRC2</accession>
    <name>A0AAD8XRC2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutaminyl-peptide cyclotransferase</fullName>
            <ecNumber evidence="3">2.3.2.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_017047</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.5" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000077">
        <property type="protein sequence ID" value="KAK1732272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRC2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016603">
        <property type="term" value="F:glutaminyl-peptide cyclotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007788">
        <property type="entry name" value="QCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31270">
        <property type="entry name" value="GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31270:SF1">
        <property type="entry name" value="GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05096">
        <property type="entry name" value="Glu_cyclase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75011">
        <property type="entry name" value="3-carboxy-cis,cis-mucoante lactonizing enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="425"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="736" mass="83450" checksum="24684B1C3FC452FD" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRF4</accession>
    <name>A0AAD8XRF4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">U-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_017081</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000079">
        <property type="protein sequence ID" value="KAK1732233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRF4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16655">
        <property type="entry name" value="RING-Ubox_WDSUB1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.550">
        <property type="entry name" value="Membrane associated eicosanoid/glutathione metabolism-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001129">
        <property type="entry name" value="Membr-assoc_MAPEG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052085">
        <property type="entry name" value="WD-SAM-U-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46573">
        <property type="entry name" value="WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46573:SF1">
        <property type="entry name" value="WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
        <property type="entry name" value="MAPEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="MAPEG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="479"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="524"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="605"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="649"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="domain" description="U-box" evidence="7">
        <location>
            <begin position="388"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="70"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="70"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="235"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1732233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="671" mass="73442" checksum="834315E04913E96D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRP1</accession>
    <name>A0AAD8XRP1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">mannose-6-phosphate isomerase</fullName>
            <ecNumber evidence="5">5.3.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_016732</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-mannose 6-phosphate = D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12356"/>
            <dbReference type="ChEBI" id="CHEBI:58735"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="5.3.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the mannose-6-phosphate isomerase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.8" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000063">
        <property type="protein sequence ID" value="KAK1732591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRP1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004476">
        <property type="term" value="F:mannose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009298">
        <property type="term" value="P:GDP-mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07011">
        <property type="entry name" value="cupin_PMI_type_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.441.10:FF:000003">
        <property type="entry name" value="Mannose-6-phosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.441.10">
        <property type="entry name" value="Phosphomannose Isomerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001250">
        <property type="entry name" value="Man6P_Isoase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016305">
        <property type="entry name" value="Mannose-6-P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018050">
        <property type="entry name" value="Pmannose_isomerase-type1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046457">
        <property type="entry name" value="PMI_typeI_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046458">
        <property type="entry name" value="PMI_typeI_hel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00218">
        <property type="entry name" value="manA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10309">
        <property type="entry name" value="MANNOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10309:SF0">
        <property type="entry name" value="MANNOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20511">
        <property type="entry name" value="PMI_typeI_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20512">
        <property type="entry name" value="PMI_typeI_hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00714">
        <property type="entry name" value="MAN6PISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00965">
        <property type="entry name" value="PMI_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00966">
        <property type="entry name" value="PMI_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Phosphomannose isomerase type I catalytic" evidence="10">
        <location>
            <begin position="16"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphomannose isomerase type I helical insertion" evidence="11">
        <location>
            <begin position="173"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="434"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="442"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF20511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF20512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1732591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="477" mass="52768" checksum="A3DF8E427E7391D9" modified="2024-05-29" version="1">MASVHTYDKSSQRHVLPLRPTIKDYAWGIRGLDSRVARFALESGVIDEVDPDSPYAELWLGTHPSGPTTLRDGTTLESVVGGQLPFLFKILSAGKALSIQAHPCKDGAKRLHLENPTNYGDDNHKPELAVALTPFEAMCGFRRLEEIAILIKKHPEFAACISNEAKLAIFLCSRDEDDKKKALRMLFQSFMSCPVETSQVQLKKLLKRLQKEQSVDHVHPHEEPPWERKCARAILRLAQQFPGDSGAMAPFLLNYLLIAPGESFYMAANEPHAYVAGEIIECMACSDNVVRAGLTPKFKDVDNLVNMLTYSMGGPTINAGTPAYGDDRIMRYTPPTREFEVMIITCNPGEDITLPALSVPAIFVVLEGSGNTDNEEGQRLVMRPGRSYYMPEHCPELTLAVNDSKRGPLRIALAHENQHLDEPTLSCAEDSKQWGGEFALPTPTSNPGTPRSPNKYVGVRELNLKPGVTVPFKVPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRQ0</accession>
    <name>A0AAD8XRQ0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Enoyl-CoA hydratase domain-containing protein 3, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_017035</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">May play a role in fatty acid biosynthesis and insulin sensitivity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000077">
        <property type="protein sequence ID" value="KAK1732260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRQ0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016836">
        <property type="term" value="F:hydro-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052377">
        <property type="entry name" value="Mitochondrial_ECH-domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006008">
        <property type="entry name" value="PRK08139.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43602">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43602:SF1">
        <property type="entry name" value="ENOYL-COA HYDRATASE DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1732260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="286" mass="31193" checksum="5BBC44F205E46F2A" modified="2024-05-29" version="1">MMINKVCILPRHWFNSRVVKHTTRRASLSSSSCCDELIRRYDDTVNSVTTLTLNNPKKYNVLSSAVLDAMQLQLDDIAANDSISVLVIRSTGNAFSAGHDLKEIHAHGTNEETVALFQKCSKLMMSVNKLPQPVIASVQGIATAAGCQLVASCDLAVAANEATFGVSGINVGLFCSTPAVALSRNVHAKQAMHMLLTGDLISSEQAVAYGLINKAVSMDTLEAETMMLAKKVASKSNYAIRLGKDVFYKQLQCDDLKDAYELTTERIASNFQHDDTKRMIAKFVNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XT01</accession>
    <name>A0AAD8XT01_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
            <ecNumber evidence="2">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016538</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000057">
        <property type="protein sequence ID" value="KAK1732826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XT01"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF152">
        <property type="entry name" value="UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="459"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="620" mass="68488" checksum="3128DEB69F2BC9EA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTI7</accession>
    <name>A0AAD8XTI7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016026</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000051">
        <property type="protein sequence ID" value="KAK1733309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTI7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="256" mass="28034" checksum="9923A5A5519675F5" modified="2024-05-29" version="1">MVPTAAAITLATHAVGNAIILYQIFSPLLEHDAIDMTHLDPSVIIDTAIPLKHLGHFLALSCILSIAIISGCQWATLTRNEIQEQSHKYLSLVNNNMILTGIATVFAQCSFILCGINPMKLPIHTFISALYVTTITVLPITLLAPSGEVIASMQHGKSRVNYEAVVAYLFGPMSNNINQSTQHKQQRQQQLYQRKVQRMHQYSTLGTLIGMCACAIFRVLDHGMQIQRYPMPIIIGATAGRVGGVLMAVLVTVTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XU10</accession>
    <name>A0AAD8XU10_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015567</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000045">
        <property type="protein sequence ID" value="KAK1733712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XU10"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051261">
        <property type="entry name" value="NLR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24106">
        <property type="entry name" value="NACHT, LRR AND CARD DOMAINS-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="355" mass="39294" checksum="0637608E84EF563A" modified="2024-05-29" version="1" fragment="single">MDHRYYNYYEANAADISLEDITSSEQNKQILRRLRDDDLGWHDHITLGREGRFYLTERCELLLIREGDDLGWLGYFIGRSVKLQGLEIWHLNLPENEGWEQQIHAFLDGVARNQSIRRICAIELGEYESTAFLRALGNWSQLEELVYSRNILDSNGCSVLGTLLESGACKLKELLLYNNNIGDDGVAALASRLRSIAPSLKTLGLSWNSIGNDGLSALVAALESCTSLEELDLSDNDFSLATAGLASLSDWLQTAVLNLNELSLRYCAINDEGLQALTEGAVNHCKGLNLSENDSITALGLRYLSTSLQCDSCRLESLFIGSINIGDDGAEVLARGLIGNKVLRCLELRDDEGDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUU5</accession>
    <name>A0AAD8XUU5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Leucine-rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015053</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000040">
        <property type="protein sequence ID" value="KAK1734286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUU5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="163" mass="17725" checksum="5CF8555B9620EA3D" modified="2024-05-29" version="1">MIRQSHSRLQETFLGHPTLLDVVCRDGVVKVAQAGFLDCPSLTRVKMPSVEGIGRGAFKDCKALMYIECGKLEFIDVGAFGHCKSLRSINLPSAKTVQMCAFSNCEALANVKFGKKLESIGFRAFNDCTSLERITIPLKDGMVSSVAFSGCENLERVDLIGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV72</accession>
    <name>A0AAD8XV72_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015212</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV72"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.200">
        <property type="entry name" value="LURP1-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007612">
        <property type="entry name" value="LOR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038595">
        <property type="entry name" value="LOR_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025659">
        <property type="entry name" value="Tubby-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04525">
        <property type="entry name" value="LOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54518">
        <property type="entry name" value="Tubby C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="134" mass="15483" checksum="F95CDE38228CDB7A" modified="2024-05-29" version="1">MDRVLIAATPSYDLYRSDGTKIGWIEKKLISFMDTFDVYMEGKGGFGVTGLFKPTPAYRIEGDFLDRNFSFKNEEGKVVARANMDSWIQIDMMNHYQVQVAEGMDACLVLACVCCIDEEFDEEHQERKKKREEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVM1</accession>
    <name>A0AAD8XVM1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ankyrin repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015035</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000040">
        <property type="protein sequence ID" value="KAK1734268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVM1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039323">
        <property type="entry name" value="ANKRD_45/46/60"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22677">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22677:SF4">
        <property type="entry name" value="USHER SYNDROME TYPE-1G PROTEIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="29"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="29"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="62"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="95" mass="10203" checksum="0EB02458F46038E9" modified="2024-05-29" version="1" fragment="single">MHKASKKGHVDLVRKLIINGADVNAKDNDEYTPLHFSCGYGHVNVAKLLIKCGAKVNAKNYAGGTPLYSACNYGHIDVGKLLIEKGADFNAKSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWE7</accession>
    <name>A0AAD8XWE7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ankyrin repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014712</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWE7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24121">
        <property type="entry name" value="NO MECHANORECEPTOR POTENTIAL C, ISOFORM D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24121:SF23">
        <property type="entry name" value="NO MECHANORECEPTOR POTENTIAL C, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="522"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="26"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="53"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="603" mass="66729" checksum="48A5336DD17B3457" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XX67</accession>
    <name>A0AAD8XX67_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Mitochondrial sodium/calcium exchanger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_013916</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XX67"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051359">
        <property type="entry name" value="CaCA_antiporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025774">
        <property type="entry name" value="PiNMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12266:SF0">
        <property type="entry name" value="MITOCHONDRIAL SODIUM_CALCIUM EXCHANGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12266">
        <property type="entry name" value="NA+/CA2+ K+ INDEPENDENT EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51581">
        <property type="entry name" value="SAM_GTMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="294"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="490"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="515"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="547"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="585"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="614"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="659"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="12">
        <location>
            <begin position="199"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="12">
        <location>
            <begin position="554"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase type 11" evidence="13">
        <location>
            <begin position="821"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="100"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif II" evidence="9">
        <location>
            <begin position="884"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif III" evidence="9">
        <location>
            <begin position="911"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="108"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1735302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1006" mass="110273" checksum="DBC5F655F072840D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXJ5</accession>
    <name>A0AAD8XXJ5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAM151 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013879</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the menorin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXJ5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019356">
        <property type="entry name" value="Menorin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21184:SF6">
        <property type="entry name" value="CONSERVED PLASMA MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21184">
        <property type="entry name" value="MENORIN (DENDRITIC BRANCHING PROTEIN)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10223">
        <property type="entry name" value="Menorin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Menorin-like" evidence="2">
        <location>
            <begin position="43"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00044953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="311" mass="35691" checksum="5A6AFF216F154EF2" modified="2024-05-29" version="1" fragment="single">LLRTRPLYWLAHPKYIRPIRHLLLLASGFWVASNIMPVPLIDFRWYHAVNDQHKLDNVLASSAKHTQLHAIEADIIYSEAKGQSVMGHPPQVDGELTLALLLQQLNEANFQSTSMTDTDANILKLDFKSMKALQASINDVENYLKDLPHQLHQHVWINADILAGPGGKGEDMQPKFDSVEFMELLTSETSLMKSITLSIGWTTSLTDIHAPYTMDMIDEMLTLLRSYPCKNITFPIRATSVLTSWEALRKLYDNNVDENKRWTLTLWWSLTSEQHKMTKDAMNRIHSLLESDYQSILPNRTFYDLVNFSPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XY35</accession>
    <name>A0AAD8XY35_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XY35"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="638"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="644"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1097" mass="123945" checksum="6977780F045FC920" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZ74</accession>
    <name>A0AAD8XZ74_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chitinase</fullName>
            <ecNumber evidence="3">3.2.1.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013301</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZ74"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00325">
        <property type="entry name" value="chitinase_GH19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.530.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22595:SF79">
        <property type="entry name" value="CHITINASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22595">
        <property type="entry name" value="CHITINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="Lysozyme-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042148018" evidence="2">
        <location>
            <begin position="20"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="483" mass="53774" checksum="C845BEF8A8524206" modified="2024-05-29" version="1">MKFYFGTFLLLLSISEADAQTATGGALSECANGGCNLGEYCVGNSFLKDVDDTGEYGCSKCNGSRDWWPCNFETTCFCHALDAPRIPPAPRSGVTVNAALDTCRDVLTEDTFNNIVQPTSEEGKQLFTYAGLCDAIYNYNQYHDEKFAQMGTVSQVRRELAAFLSHASVETDGFSVTREEHHCVNPITGLDGNVYCMPCKEQFYSKETKTCTQSYFVDEQSYYKYCDLSRQNNQGCSCTVAGVKMANVPLQDDLRAPAIGYVRADDMYFRRGSFDTSFNYGYMGAGIAIKGDAQYFCEQPDLLATNPQYAWQSGIYKWMEYMPYEFGSTAHKQALKGNFGGTINVLNGPLECPSSMNISEKHVQMVRDRVREICRAGSALGVMLELNQCENSYDRDCQKCDGLEDIYYSCQQDGSCPECNGWEENLLSLAPTVTPAIVKPPTFEDWGKYWNNPNPGTRNGATSSYPSSVWYSIVSVVVLIIHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZM4</accession>
    <name>A0AAD8XZM4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012957</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZM4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039872">
        <property type="entry name" value="KIAA0513"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13663">
        <property type="entry name" value="SIMILAR TO RIKEN CDNA 6430548M08"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13663:SF2">
        <property type="entry name" value="SIMILAR TO RIKEN CDNA 6430548M08"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="515"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="569"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="769"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="791" mass="86894" checksum="37E8820119F7D411" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y009</accession>
    <name>A0AAD8Y009_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA-directed primase/polymerase protein</fullName>
            <ecNumber evidence="3">2.7.7.102</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_012494</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:22509"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ssDNA + n NTP = ssDNA/pppN(pN)n-1 hybrid + (n-1) diphosphate.</text>
            <dbReference type="EC" id="2.7.7.102"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.102" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1737049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y009"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006264">
        <property type="term" value="P:mitochondrial DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009411">
        <property type="term" value="P:response to UV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044917">
        <property type="entry name" value="PRIMPOL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31399">
        <property type="entry name" value="DNA-DIRECTED PRIMASE / POLYMERASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31399:SF0">
        <property type="entry name" value="DNA-DIRECTED PRIMASE_POLYMERASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03121">
        <property type="entry name" value="Herpes_UL52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="430"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="430"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00026139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00044677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1737049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="605" mass="69188" checksum="64CF027F2824BBBF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0J0</accession>
    <name>A0AAD8Y0J0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0J0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042246015" evidence="2">
        <location>
            <begin position="24"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="176" mass="20817" checksum="93A663A5AF77DEAC" modified="2024-05-29" version="1">MKASLLSTPLGLWLLTITHQAHARPDAHQQFEHTAASGDIQKKKKIDRHKQRKQIATDTRQQISSGSIPSDNDFHKSFHRRQIEKQIRLDQLHAQVSETLTAHHSGQRKLSDAELESHTKKQMALERKRKSLQDLTPERYLERMKRQEEKLVKKVERKERRKEERFRMMMDRGGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1G4</accession>
    <name>A0AAD8Y1G4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Palmitoyltransferase</fullName>
            <ecNumber evidence="14">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">QTG54_012013</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="14">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the snRNP core protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="14"/>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1G4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01721">
        <property type="entry name" value="Sm_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000002">
        <property type="entry name" value="Small nuclear ribonucleoprotein Sm D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034099">
        <property type="entry name" value="SmD3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12246">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 14 17" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="10" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 14 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Sm" evidence="16">
        <location>
            <begin position="369"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="480"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="15">
        <location>
            <begin position="486"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1737146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="534" mass="58632" checksum="4DE7E64228CB0940" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1K1</accession>
    <name>A0AAD8Y1K1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012002</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1K1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="570"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="236"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="577"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="622" mass="67355" checksum="646E7664C446E1A3" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y239</accession>
    <name>A0AAD8Y239_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cupin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010873</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y239"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042157735" description="Cupin-like domain-containing protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="392" mass="45016" checksum="44EE80497A6C837F" modified="2024-05-29" version="1">MVMKSLLLFCCTTALLYSPTVVHSMSEEHRLEQRQKHGYAQWPPTVVPNTPGWNRIMNRRFEQISRIRNRDDKWNAWVAIMTSALIATNYTENGWGLTRAPDHITRRLQLRLNRTLLEEGIIDPSGKYTYKEHYIPVIGGEEHARPLMITNAHDNREILNEMTPFFEWWSGIDLKPSIAYGIRAYRNDSNLLMHIDKPTSHVISGIYHVGRSEDAEPWPIVIEDFHGNTNQVYLTPGDILFYESSKCNHGRPQTFYGGYYASLFMHYAPASPDFDGKALLHERDLAVPPHWHVDFPPQEGLDEFEMVGTSFKEPKCKNLLCSLDETSEQSKNTVNWYGPAPKGMIVTNGWDPETMEPPKEWVERGYDGGKKRDGNADGIDSDNSSDEEEDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y271</accession>
    <name>A0AAD8Y271_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">3-phosphoinositide-dependent protein kinase</fullName>
            <ecNumber evidence="9">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_011751</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y271"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="242"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="197"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="520"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="901"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="200"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1737465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="951" mass="107002" checksum="9DC82F492819B8C5" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2P5</accession>
    <name>A0AAD8Y2P5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transglutaminase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2P5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.620.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35532:SF5">
        <property type="entry name" value="CARBOHYDRATE-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35532">
        <property type="entry name" value="SIMILAR TO POLYHYDROXYALKANOATE DEPOLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transglutaminase-like" evidence="1">
        <location>
            <begin position="149"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="294" mass="32936" checksum="2138CF8E523E7F3A" modified="2024-05-29" version="1">MMQYLARHIMPYDVPNIASLGFQSNGQPKPDGMSDGIVDQTVYYSIQAKTLYPWTDSIPQDVYFEYVVPYAVTNEPRTNHRPLLFNALEGSLKQYERAAIGNSTQSTQDQIKEVVKLINTELWALMGRDSKPIVFKASQTPRIYDPLSVIAYGYSSCTGLAIMLVSALRSVGIPARMAGTPAWYGDPSKGDHSWVEVYVVSNETGKDGEWMFLEPTPGIAEGKEDTANADNLDRDPCKRWFCKADRFNGSTKTYATRYDKQATSFFPMAWADDDRGVPGEDRSKFYTSTCGKCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2R0</accession>
    <name>A0AAD8Y2R0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010594</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2R0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="1">
        <location>
            <begin position="285"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1178" mass="133045" checksum="AF350036C4C1155B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2W2</accession>
    <name>A0AAD8Y2W2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011106</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="153"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="282"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="524"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="567"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="611"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="798"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="920"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1253"/>
            <end position="1284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="181"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="539"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="576"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="652"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="666"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="685"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="925"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="938"/>
            <end position="953"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1322" mass="145492" checksum="496A6FCBFDF62C31" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3U1</accession>
    <name>A0AAD8Y3U1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3U1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="242" mass="25596" checksum="452ED37EEDBEC1C9" modified="2024-05-29" version="1">MSHNPDHRAPAPAPAYDFFSPPPCNPDYRENNTEEDYAIPPSGEDSSAEQNATTQRTKRQAAGVAVGAGLAGLVVSGPILGAAAAGGAVYAATTNSGVAGSVARQTGESVASAGDKCKEIDKKHAIMKRSSQLVKTAAKKTREFDEKHKITSKSIRTSKKIGNSALEGAKKVDEKHHVVDNTKLAAKKAIEKAKDVNQKHHVTEKTVKAASFTSKKVLAGAKFVSSKVMAKEKKFATTTVYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y419</accession>
    <name>A0AAD8Y419_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010494</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y419"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="451" mass="51656" checksum="3C298C396E39A6EF" modified="2024-05-29" version="1">MATRSSHLRQAVSIGASLSFALAIGLGWYANRLRRSRWLETDKEQNQETTHSVINHFSSLILDPETTVEEANKRRTTSYYLKMREAHHKSLVLGVYPSRLKKLRKKEIDRTLSYWNKGNQSHRTIVCMCDEITQKVLSNARRLVLAPLQYSSDIDSLSAWIPDLNIIPKEDMHVTIALPWWWHTIRPGNNELTKKMANRFKQTLLVEFHYGFQIELERIVLLGGKVLVALWRCVGERETDDGRVIVDRHGTNIDPMVWLREEIVRCFITESPDQRRQPLTYQHNKSEGDRAEENAWQHTIMQRTPGMGKPGSADGFIHTTLCRLPLDCLSSKDIELDELHRLCRELSATLNGHRMVVDKYRFIETMGEGGESNPCYKPIYDEIIEAPARHEVHIDGTVESRNAQVSDVLERHNTIGPSGNFWNEEVVAPAPSTDTQASGTTLSALFEPPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y427</accession>
    <name>A0AAD8Y427_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_009797</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y427"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070042">
        <property type="term" value="F:rRNA (uridine-N3-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019446">
        <property type="entry name" value="BMT5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10354">
        <property type="entry name" value="BMT5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="311"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="278"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="288"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="298"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1739254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="521" mass="58448" checksum="8E6B56AFE5FDC97B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y443</accession>
    <name>A0AAD8Y443_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010159</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y443"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="345" mass="38045" checksum="19F3D039273696F5" modified="2024-05-29" version="1">MKRLLSLQQWPIIMAFAQAASDRTSSAQQLPLTPSFHKFHDAAFELLPSRSGSDAILNRLQQLANAYPTYVTLTTTQKLFGLDDGQQQHSYAVIIQDKQATQDIQDHRRTDVSSSAQLELVESSTSNNMKDVVDWFHHSIQNDDASASDGAASTKEEEAVPSTTTTHADIILNAATIGSDKVIGLAEVMLQAANCESVNDSHDGGNSNANFLSDRRLQCRNNLKDAGVGSKDVEWLANVVFTRRTIILSSAATHGSAAPHHGSLSLLWLVVACVGLFLAVAFMTVLTLKRKHRGRIWLEEEAKRRVAEVDYSSDFIQKDFTRELTSFDEELTVQLIEPSHNVILV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4M0</accession>
    <name>A0AAD8Y4M0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Chloride channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_009910</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the chloride channel (TC 2.A.49) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4M0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04591">
        <property type="entry name" value="CBS_pair_voltage-gated_CLC_euk_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3080.10">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051280">
        <property type="entry name" value="Cl-channel/antiporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="ClC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11689">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11689:SF136">
        <property type="entry name" value="H(+)_CL(-) EXCHANGE TRANSPORTER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0129">CBS domain</keyword>
    <keyword evidence="9 11" id="KW-0868">Chloride</keyword>
    <keyword evidence="6 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="354"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="444"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="483"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="568"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="593"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="634"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="13">
        <location>
            <begin position="844"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="24"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="70"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="73"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1739367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="913" mass="100491" checksum="781662A9F8F4347D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5M9</accession>
    <name>A0AAD8Y5M9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WRKY transcription factor 19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010098</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5M9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="277" mass="29481" checksum="E6C3D05907B1F65F" modified="2024-05-29" version="1">MSEEEDLAVLIYKSSKTAKARAAAAAAKEKGRMNASSTGWRTSTRKRSSSEQDDEASMDRPGKKTAKQGATKKKLCSSEGCTNQVVQGGVCRRHGAKLQLCKSKGCQNISINGGVCIRHGAKRKLCDSEGCTNHVVKGGVCRRHGAELKLCSSEGCTHISQKGGMCKRHGTMRKSCSSEGCTNLVQQGGVCYKHGAKRNRCSSEGCTNLVVQGGVCRRHGAKLKLCSSEGCPNLAQKGGVCKRHGAKKKTCSSKGCTNQATQKGGVCKSHWAERTRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5Y6</accession>
    <name>A0AAD8Y5Y6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009577</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5Y6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1739818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="237" mass="22221" checksum="BC425DDE3FE44525" modified="2024-05-29" version="1">MTMMLDIDRPDGPLLPGEHAVPGCKQEGVGLLDGDIVGLPVGDFVGLLEGDAVGLLVGGSVGLLDGDAVGLFDGDSVGLLVGGSVGVVDGDAVGVVDGDAVGLLVGGSVGLLEGDAVGLFVGGSVGLLDGDAVGLFDGDSVGLLVGGSVGLLDGDAVGVVDGDAVGLLVGGSVGLLDGEAVGLLDGGSVGLFDGDAVGVVDGDSVGLLVGGSVGILDGDAVELLDGDAVGLLEGEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y613</accession>
    <name>A0AAD8Y613_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Endo-1,4-beta-xylanase</fullName>
            <ecNumber evidence="7">3.2.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_009622</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 10 (cellulase F) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y613"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044846">
        <property type="entry name" value="GH10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001000">
        <property type="entry name" value="GH10_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490:SF1">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00331">
        <property type="entry name" value="Glyco_hydro_10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00134">
        <property type="entry name" value="GLHYDRLASE10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00633">
        <property type="entry name" value="Glyco_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51760">
        <property type="entry name" value="GH10_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH10" evidence="6">
        <location>
            <begin position="58"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="423"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="435"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1739863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="462" mass="51541" checksum="702E156082D529A3" modified="2024-05-29" version="1">MTSDETLSSIASRCCKRVYIGTAVLPKPLFLHEHQDHKGIPCATISTVDQNQIPDPAATPTNELPQYTHTILSEFNSIVIEHHLKWGPLVHTLPGPISQSSPPTMHLGKYDFSHVDAMVDFAIHHNLHIKGHVLIWHVTSPPFLEDMSPTQVREAVKRHIFTTMNYFKGRIKMWDVVNESLAADGTLVENVFYRKMGPDYIEQCFRWAHEADPDAFLIYNDNKVEGCGAVETNDGDSCSSDGHSKAPIQAKADGFYNLLQDLVEKGVPIHGAGMQGHFSAGGTKHQRPPTPAMVKRQIRRIGELGLKVNMSEMDVRISKLPASADDELKSTAQTQIYQDILSAALSEPSFDGIWLWGFADRHTWVKNFYYDDAPLIFDEKYQRKESYVGVQNALKTLCPGGRVGEMVGGESAQCFLEQDVDENGNAWGEGWMQPEPKEDGNGEKNGDSTKEGQPDWLLPDTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y617</accession>
    <name>A0AAD8Y617_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_009524</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y617"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17961">
        <property type="entry name" value="DEADc_DDX56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF21">
        <property type="entry name" value="DEAD-BOX HELICASE 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="50"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="276"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="366"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="462"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="589"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="672"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="381"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="594"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="689"/>
            <end position="704"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1739765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="713" mass="78934" checksum="F24099064573792C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y628</accession>
    <name>A0AAD8Y628_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF839 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009539</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y628"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008557">
        <property type="entry name" value="PhoX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35399:SF2">
        <property type="entry name" value="DUF839 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35399">
        <property type="entry name" value="SLR8030 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05787">
        <property type="entry name" value="PhoX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63825">
        <property type="entry name" value="YWTD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="420" mass="45278" checksum="DF84560199852255" modified="2024-05-29" version="1">MTTEPSSTPSSSASPSSIPSFLPTVTTEPTSTPSAHPSISTQPTSSPSAFPSASPFVLFTYGESLYTDNDLGIQISVGLTAKQIAQTGSRVSYANGGQSSISYHEAMDGAGIAQLPDGGYAYLSNAEKSSGAGGVYGLYFNKDGQITDYKALLTGTSRNCGGGMSPWNTWISCEEAGGGQCWQIEPDPNKPNHNSPKATLLGGPSGGEYETVAVDNTNKNKPVFFVTEDESDGELRRFEADGYGWDALHVGGRTTYLEFLDGNRFQWTTSLSAGENSAASYYPNAEGIIYHNSTLYFVAKVTRTLFILDLNDMTYTSERTGSSWVGQGSFNSQPDQIIESDLDERKYIYFTEDGGSAPGVHVRDREGKYYTMVRGVPGGRYSGDETAGIAFSPDRKKFYFGFQDAGVLMEVTRYDGHVFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6J8</accession>
    <name>A0AAD8Y6J8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heat shock factor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_009731</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6J8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000479">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF206">
        <property type="entry name" value="HSF-TYPE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="6">
        <location>
            <begin position="23"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1739972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="326" mass="36692" checksum="478DBBA01A967E37" modified="2024-05-29" version="1">MNVNQTTPTNNMTASSSSTPRRTKAEFPIKVYAMLELADNIFEFAQAVTWLPHGRAFGIHNKVKFMEEVVPMFFNQTKIRSFNRQLHLWGFRRIGRGDEQVWHHDNFLRGKPEDMKHMVRTKIKGNTAISSEDVIVPNFDDLPPLPVCNKRPTAILDVMEDAIMKLPSASASGAITHCGSTMPTVSPPQPQPGIFNGDCQMVLPNHFNLDCNQDEEIPSPPLFQRRVSTESEFMMHPCIPIMHCHLPLQAGNIELTQPMHETSMEGSSHQAQSHIMCQDDFNDLCFSPLKQNNEDFEPLSFMDDNAPCDDFASFIEGAIHQIGGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6V8</accession>
    <name>A0AAD8Y6V8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6V8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005046">
        <property type="entry name" value="DUF285"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03382">
        <property type="entry name" value="DUF285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042089623" description="SnoaL-like domain-containing protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="94" mass="10356" checksum="D636F05E69125ECF" modified="2024-05-29" version="1">MPVSTLVPSVLFLLIISLSSRANAAQQCFAADGVDLKAAVNKYYAGNWAAADTEKYGTIEDWCTKFVTTMRDLFRDKHTFNSNISAWDTSSVPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y773</accession>
    <name>A0AAD8Y773_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008258</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y773"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34407">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34407:SF1">
        <property type="entry name" value="SGNH HYDROLASE-TYPE ESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="442" mass="49272" checksum="CAB0CC211CC9F749" modified="2024-05-29" version="1">MACGINHVGITQPGWVRQYTECAWPARLEHLFNRVLFQGKEVVKVSNLAVGGSNSEVGKAVLEYHLFPDAFDQPDIVIWSHAANDAQEKDKERAFFESIPGFVNAAHNLRICDDHLPLVVMNEEFFGQDNDISGAIYKASNWFGLMGISQRNVISHKTFAKFDNDDYVNSIIDAKGVHPGMGGHIGASWTVFYNFISAFTDACDYRRVSSSPTSIASPDVAAKKIGPYKENGYGDISSEWKKHQDKVREMCARQEQEVSTSNNDETAATTTTSNQQLHPPCTYAFMVNPMTSIRTSGDVNKKMNEVLISNTGWNAEGFPVKQPRAGFYAKEPNAHFSLKIDASMETKYMTIMSMKSYGDNFKDTILEVDVQIQRKGDAAEEEVVKSSKYEVTGYHETKTSIHIPHKFELPDGGAEKGDSIVVNFRLVSGSYFKIAGLAFCRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7C4</accession>
    <name>A0AAD8Y7C4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_008381</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7C4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF36">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="3">
        <location>
            <begin position="92"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1741129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="151" mass="16338" checksum="0723568EDFCC4BF2" modified="2024-05-29" version="1">MHGNSGKGIDASMIEIKELEEVDEERKVVTSLMQSIVTQPMSTEPMNSATSNAPVLSYSSRNANKESLPPVLMHKLRKEYPSLGGAPAKVALNSLDLHVERGRVLGLLGKNGAGKTTALKILAGMHDSSGGMDLWLDLTSKRNDLMLQEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9V6</accession>
    <name>A0AAD8Y9V6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DENN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006767</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032483">
        <property type="term" value="P:regulation of Rab protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001194">
        <property type="entry name" value="cDENN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005112">
        <property type="entry name" value="dDENN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043153">
        <property type="entry name" value="DENN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051696">
        <property type="entry name" value="DENN_Domain_GEFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037516">
        <property type="entry name" value="Tripartite_DENN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005113">
        <property type="entry name" value="uDENN_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12296:SF21">
        <property type="entry name" value="DENN DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12296">
        <property type="entry name" value="DENN DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03455">
        <property type="entry name" value="dDENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02141">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03456">
        <property type="entry name" value="uDENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00801">
        <property type="entry name" value="dDENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00799">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00800">
        <property type="entry name" value="uDENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50211">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDENN" evidence="3">
        <location>
            <begin position="752"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="1">
        <location>
            <begin position="1486"/>
            <end position="1522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="31"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="213"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="294"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="434"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="558"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="689"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1288"/>
            <end position="1327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1715"/>
            <end position="1763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="213"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="323"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="337"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="348"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="393"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="464"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="701"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1303"/>
            <end position="1327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1715"/>
            <end position="1724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1742202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2091" mass="230862" checksum="1EE7E85FCFF7E9B4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAJ2</accession>
    <name>A0AAD8YAJ2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glucose-6-phosphate 1-dehydrogenase</fullName>
            <ecNumber evidence="8">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_006451</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15841"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="1.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glucose-6-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAJ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004345">
        <property type="term" value="F:glucose-6-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009051">
        <property type="term" value="P:pentose-phosphate shunt, oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00966">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019796">
        <property type="entry name" value="G6P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022675">
        <property type="entry name" value="G6P_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00871">
        <property type="entry name" value="zwf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429:SF0">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02781">
        <property type="entry name" value="G6PD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00479">
        <property type="entry name" value="G6PD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00079">
        <property type="entry name" value="G6PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00069">
        <property type="entry name" value="G6P_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 8" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="5 8" id="KW-0521">NADP</keyword>
    <keyword evidence="6 8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="570"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1742854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="602" mass="68073" checksum="B1112D79C3E32FF0" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBC0</accession>
    <name>A0AAD8YBC0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006675</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1743078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBC0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="597"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="627"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="699"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="818"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="632"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="733"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="763"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="820"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="830"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="840"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="990"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1030"/>
            <end position="1039"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1047" mass="115590" checksum="2AB33599C0DC56AA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCC3</accession>
    <name>A0AAD8YCC3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005829</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCC3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="298" mass="34490" checksum="48372A139E22C5FF" modified="2024-05-29" version="1">MEAPESVIRPPSSNNGAKGSRRQLYVIGGIASFMFMLFVILPQQYAWMTNEMEVHQPVNHNLTHHHEIIETVPVTIVCQLSGEMGNNLGKLGRCMSLKWWLESGAFYNSTNKLGYSARVALRHQQHNKWVRGAQDLQRCFPNTNQFDFSEANNNEFADIWKMQHQLLGGDERVEANSPFHEINSIDEKEIVSGLQSFVSEASKHHAMVYNAASKRNVSLPFLFSAQFQNLPLEDRFHEEIRQFFRFNESSCCKVMADPDENVFHYRNFKKEMPKRWNSYGFTKLIHSKQLICLDTKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCQ6</accession>
    <name>A0AAD8YCQ6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Calcium/calmodulin-dependent protein kinase II association-domain domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005618</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCQ6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004683">
        <property type="term" value="F:calcium/calmodulin-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013543">
        <property type="entry name" value="Ca/CaM-dep_prot_kinase-assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011944">
        <property type="entry name" value="Steroid_delta5-4_isomerase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02246">
        <property type="entry name" value="SgcJ/EcaC family oxidoreductase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08332">
        <property type="entry name" value="CaMKII_AD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041907631" description="Calcium/calmodulin-dependent protein kinase II association-domain domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium/calmodulin-dependent protein kinase II association-domain" evidence="2">
        <location>
            <begin position="79"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium/calmodulin-dependent protein kinase II association-domain" evidence="2">
        <location>
            <begin position="211"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium/calmodulin-dependent protein kinase II association-domain" evidence="2">
        <location>
            <begin position="336"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="477" mass="52937" checksum="3AAC265068B951AB" modified="2024-05-29" version="1">MRFTAAILSIGLTRLTHSSAFAPVAITAASRSLSTTTSLSGGVLTDLVNAIDAPRITKVPAAAFSTAAPSPPTMPDITETEVRALFELWNQALATGDSRIVADRYIKSPMLLPTVSDQPRTDFDSVKDYFDAFLLKEPQGKILEGKIYIGDGWASDTGIYEFTMGTTGDKVKARYSYNYVQEDGQWKIQHHHSSVMPEEIALGKSITEDGVRELFGLWNNALATLDPKKVAARYAREGVLLPTVSDVPRTDFTSIEDYFINFLKNKPQGEILESHVTIGKNTCSDVGIYEFTMGSTGAKVKGRYSFVYVWEDDEWKINHHHSSVMPEGTMAQPIKEEEVRNLFQLWNSALATEDPDAVAKRYAKNAVLLPTVSDVPRTNYDLIKHYFVGFLTKKPQGEILESSVTIGHNWCQDAGIYEFTMGTTGDKVKGRYSFVYVWEDGQWKISHHHSSVMPEPFLGPAPKPVEESVEGVDTILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD42</accession>
    <name>A0AAD8YD42_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">U6 snRNA-associated Sm-like protein LSm3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_004794</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD42"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120114">
        <property type="term" value="C:Sm-like protein family complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01730">
        <property type="entry name" value="LSm3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034105">
        <property type="entry name" value="Lsm3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040002">
        <property type="entry name" value="Sm-like_LSM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13110">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="9">
        <location>
            <begin position="3"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1744261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="112" mass="12979" checksum="41937765124A3B54" modified="2024-05-29" version="1">MEEPLDLIKLSIDERVYVKCRNERELRGKLHAYDQHLNMVLSEVEETITSTEEDEETGEEIVNKKTRSVGMLFVRGDIVVSLLWNMNGSTNHNCKLIWTWYALKDVPSAPVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDL7</accession>
    <name>A0AAD8YDL7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDL7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041944938" evidence="1">
        <location>
            <begin position="29"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="233" mass="25535" checksum="651C005B0B73D1A4" modified="2024-05-29" version="1">MMHTIAATTIAITAQLFLALSWITPTAATDVIGSVLGSSSCRLEQAECVCSPRTFTFRLNFNGSCDINTIQGNPGVNGTQCELRGFPTENEVEDKTPVEVASVDIQEVNVDVDGNQHWRWKRFEGPFYDGDTIEYTSMSDSLKSDEPLGEQDVPKGFFISFTGKNAGDEYLFHGIIWMYNLDNCDAEPITEGNAIGLFEVVEYTSAIPAFCPAVGLTSFELDGDLVANKVKME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDT9</accession>
    <name>A0AAD8YDT9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_004961</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDT9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052420">
        <property type="entry name" value="Espin/Espin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153">
        <property type="entry name" value="ESPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153:SF8">
        <property type="entry name" value="FORKED, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1744428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="196" mass="21971" checksum="992E338D4C90727A" modified="2024-05-29" version="1">MSLSINKFMNYVAIVLDLIHRQEWAALEKVATTKHKLFKVISEHIKKCDEFNGMTLLHAARCTHGQDCVGRTPLHVACGTGADAEIIRLLVEAYPQACDLQDEDGRLPLHLACDIECVLFEGDQTERAPPTIDVVRALLSGSWRSVLVEDEDEMSPIEYAIVSDANIKVVKLLQKTSMTLRRKEAQANCKKYSKGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDV7</accession>
    <name>A0AAD8YDV7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDV7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="120" mass="13501" checksum="88D30C50C03D72BD" modified="2024-05-29" version="1">MLDMLMAMMPSKREPEFLPFPFDGVLIRRKNRVNTSLEVDKKMDEEMAEAESSCPGLHLSMDNGDDDDGEDVIAVFKKKKSSSRTATDSLIESNNSNGLQTEREGIHQEEKSSWCNDKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEB7</accession>
    <name>A0AAD8YEB7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Altered inheritance of mitochondria protein 24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEB7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.160.10">
        <property type="entry name" value="Mitochondrial biogenesis AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002838">
        <property type="entry name" value="AIM24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036983">
        <property type="entry name" value="AIM24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016031">
        <property type="entry name" value="Trp_RNA-bd_attenuator-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43657:SF1">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 24, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43657">
        <property type="entry name" value="TRYPTOPHAN RNA-BINDING ATTENUATOR PROTEIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01987">
        <property type="entry name" value="AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51219">
        <property type="entry name" value="TRAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="440"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="478"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="555" mass="58181" checksum="73A1DD9A2F2200E8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEK0</accession>
    <name>A0AAD8YEK0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bestrophin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006161</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEK0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030552">
        <property type="term" value="F:cAMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004862">
        <property type="term" value="F:cAMP-dependent protein kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034236">
        <property type="term" value="F:protein kinase A catalytic subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021134">
        <property type="entry name" value="Bestrophin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050503">
        <property type="entry name" value="cAMP-dep_PK_reg_su-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635:SF152">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE TYPE I REGULATORY SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01062">
        <property type="entry name" value="Bestrophin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="316"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="493"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="520"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="107"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="590" mass="66722" checksum="2BFF08058FC460BC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YF65</accession>
    <name>A0AAD8YF65_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003310</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YF65"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="270" mass="29740" checksum="4605183A7BFAF4B4" modified="2024-05-29" version="1">MDNSNAIEEGQGNGIPAAPAANNKQKKKLKKIANHTPMEILHGTLAILSVGTSLSGIILTIADSATRGITIFAGALTAVIGPYVYYQQTKLTDIIALKETYDAIGREVGRLAAENRRLHDTMGDLKQSIDHLEDMETALDVITDRQGQSIDAYADYVEDSAEILVQMQKNLKAYVLQNLLQVVIHHDRDHDMLVEESEIGNLIRRIKMINGVDVVEEEFRELVIKAGGSLSAIMDIIKNSMLDDDDDELRSSVFILKDSVHSSRGGSERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFV3</accession>
    <name>A0AAD8YFV3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFV3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="496"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="517" mass="59002" checksum="11E83919E807C220" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YG74</accession>
    <name>A0AAD8YG74_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">HECT-type E3 ubiquitin transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_003928</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1746004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052113">
        <property type="entry name" value="FYVE-type_Zinc_Finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39490">
        <property type="entry name" value="ARRESTIN DOMAIN-CONTAINING PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39490:SF8">
        <property type="entry name" value="ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="WW" evidence="6">
        <location>
            <begin position="6"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="6">
        <location>
            <begin position="92"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="7">
        <location>
            <begin position="221"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="CAP-Gly" evidence="8">
        <location>
            <begin position="1972"/>
            <end position="2008"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="185"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="305"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1746004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2332" mass="252129" checksum="2E721F0A378DD6F3" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGP1</accession>
    <name>A0AAD8YGP1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aspartate aminotransferase</fullName>
            <ecNumber evidence="8">2.6.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_003867</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.1" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGP1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033853">
        <property type="term" value="F:aspartate-prephenate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033854">
        <property type="term" value="F:glutamate-prephenate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004069">
        <property type="term" value="F:L-aspartate:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000033">
        <property type="entry name" value="Aspartate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050596">
        <property type="entry name" value="AspAT/PAT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46383">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46383:SF1">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042009390" evidence="6">
        <location>
            <begin position="24"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="7">
        <location>
            <begin position="77"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1745943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="440" mass="47003" checksum="85A276774D322633" modified="2024-05-29" version="1">MTRTVVFTATAILIGQSLSSCAAFSPAASTSSFSFALNDAVNTPVEPPLNPLLSQIKPSKTVEVFSLVKQMEAEGETVTSLCVGEPDFAPPQCVLDAATAAMNGGQTRYTAVTGTADLRKAIAEDLKSRKGVEYNPVTEIVVGNGAKQCVYQGLLAACGAGDEVVVPAPYWPSYPEMALLVGASPVILETSVDDGYLINPDALDKCLEEHPKAKVLMLCNPSNPTGGVHSTELLTQIAKVLEKYPNVVILADEIYERLVYTDDGQCTSFASLPGMFSRTITINGFSKSHAMTGFRLGYLAAPERFAKATSVLQGQITSCASSVSQAAGVSALNDVDDSWLENNVVIMKEKRDYVLQELAKMDGVSVSVPPNGAFYVLPDVSKYYNGDDTQLCLDLLKEKKLALVPGESFGAPGTVRISYATSMEELETAMTKLREFLESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGS5</accession>
    <name>A0AAD8YGS5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002848</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGS5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="112" mass="12846" checksum="C0AADD0522AD2618" modified="2024-05-29" version="1">MTLNKFSNTLNVTQMRLPATILVPTFPDKKDEEELDLQSLTEEDLKLLKKTDPFLYYSIPAVNKAALSLKKVDHSKASQSQSTKLHARSDLHLSAIRPWQWMSCSSVWERLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGZ9</accession>
    <name>A0AAD8YGZ9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004561</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGZ9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C19 ubiquitin carboxyl-terminal hydrolase" evidence="2">
        <location>
            <begin position="80"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="152"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="208" mass="22420" checksum="17AE2E19443196DE" modified="2024-05-29" version="1">MPPYQQPETPSSTPPPPPMSSAGLPTLSSSTAQALLGQRDSCNAANNHIMASTSVDSGLEDVEIPPNFRPPPPPREVASGVANLGNTCYMNAALQALAHAPELCHALDAESHIKRCPVALRNERRRRKLQRENASGNVSNAATNAKSHRRISSGSSKGSTNSKNQRSKKVLKRIEKDPQQGALLEKKPTPMLISDRMKMSMNIVLSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHG9</accession>
    <name>A0AAD8YHG9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHG9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="91" mass="10145" checksum="29DDFCDA89971880" modified="2024-05-29" version="1">MNLAVGIEAIPISMGRTDSVFYCGLLASWLGQVPGVLLLTKYWRNDLFALYSGIAGGYCVLVFLYAYIVLNSDWKKYSEIARKRVEVSDGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHT9</accession>
    <name>A0AAD8YHT9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2',5'-phosphodiesterase</fullName>
            <ecNumber evidence="3">3.1.13.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003728</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.4" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHT9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004535">
        <property type="term" value="F:poly(A)-specific ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000288">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF37">
        <property type="entry name" value="2',5'-PHOSPHODIESTERASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="611"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="923" mass="104106" checksum="8F8C4482B267154F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJG3</accession>
    <name>A0AAD8YJG3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001677</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJG3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="245" mass="26924" checksum="B1C4606351BC9114" modified="2024-05-29" version="1">MQPSNAVSFAVDTSSSDTEGNVEIHSSHVGETLSFDQKLRPRPSSATGQQLALSNGESYPTPLTQSATALRLRTYNAFPASDEALTSHYSADLELSFNLWMCADGIDVLASSYARVVVDPVILSSSEKDISGPLAARIVSAWMSGHGDDVYADKIIRAVAERSAQDSILGMTKDHSMSDRKLLVDKIKVLNDMLLGYLRKPSTRPLFQQALVKSAAHFLGMLRMSTRRMIFTRKKTSTMQRKRHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJL2</accession>
    <name>A0AAD8YJL2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC1 kinase family protein</fullName>
            <ecNumber evidence="3">2.7.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003089</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.-.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJL2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05121">
        <property type="entry name" value="ABC1_ADCK3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050154">
        <property type="entry name" value="UbiB_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566">
        <property type="entry name" value="CHAPERONE-ACTIVITY OF BC1 COMPLEX CABC1 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566:SF128">
        <property type="entry name" value="UBIB DOMAIN CONTAINING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="2">
        <location>
            <begin position="160"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="600" mass="67240" checksum="8F5E8CD0496AC3CE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJU8</accession>
    <name>A0AAD8YJU8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Importin-13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_001400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the importin beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJU8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051345">
        <property type="entry name" value="Importin_beta-like_NTR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363:SF33">
        <property type="entry name" value="IMPORTIN-13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363">
        <property type="entry name" value="TRANSPORTIN 3 AND IMPORTIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1747437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1108" mass="119804" checksum="01E50960E15027EE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJW9</accession>
    <name>A0AAD8YJW9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001326</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJW9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="349" mass="39918" checksum="B200250DD6AC0709" modified="2024-05-29" version="1">MTLANSDLKCIKQQYRRRWKSAQSEESDPLAYFEIDFHRPVQVNELRIQFKADLLAWTALSIKRVGMRRLIGKNAAPQLPSRLFTAMQNAKQKYLRARMLLQSASTPHIILNAGAFTMNKLHPPPPPPPPPPPSESKDETFIDGWLQQKSKQLPSSENMQRKRQQWYSKQCLFPTHITEASMVDTSPLLSLLHDHAIESDDSSLRHPSDKQPTVDEMRKIASLCATYKTTAIQNKKEFEYKRAVIAKERQSEIELPAKPPDHPEFTPLKPAENVLLAKIHGTNYNLCLARAVCPQRTNNMLKCWKSTDPRVVKALVEQGLDQLMCMEEREAVERCIGQSVQKIMKDIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLR2</accession>
    <name>A0AAD8YLR2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Serine/threonine-protein kinase</fullName>
            <ecNumber evidence="7">2.7.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_001508</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLR2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345:SF91">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE PLK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1747545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="222" mass="25461" checksum="884F3F37E554DE5D" modified="2024-05-29" version="1">MPFCRGGDLFGVVLEVAERRQQNEAELGSGGMLEPVARYWFRQLLFGLHYLQTRGICHRDLSLENILVDVNHCLVIDMGMCLRVPYYCHHDPRRSSDVTEGDTRRLIVPMGTCGKINYMSPEIFANREHFDGFAVDLWAAGVILYIMVTGFPPYDAPSERDERFGLIAQGLLNQQLQAWEIFLSDEIAHLLQWMLRPNPADRPTLKQVMMHDWVVNGEVMPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLW1</accession>
    <name>A0AAD8YLW1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">EH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_000732</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLW1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09913">
        <property type="entry name" value="EHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040990">
        <property type="entry name" value="DUF5600"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031692">
        <property type="entry name" value="EHD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216:SF31">
        <property type="entry name" value="AT21416P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216">
        <property type="entry name" value="EH DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18150">
        <property type="entry name" value="DUF5600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16880">
        <property type="entry name" value="EHD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042234541" evidence="7">
        <location>
            <begin position="36"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="domain" description="Dynamin-type G" evidence="8">
        <location>
            <begin position="342"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="85"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="85"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="147"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="233"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="262"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1748793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="689" mass="79042" checksum="376E8B2E7A2E3732" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YN73</accession>
    <name>A0AAD8YN73_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sfi1 spindle body domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000488</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YN73"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="419"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="448"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="482" mass="54523" checksum="81E8112565513684" modified="2024-05-29" version="1">MSRTSFGAYEEGKDCSTWDEKIDWSRSGNFTFASPVSSSESEAPPPPPTDDSDSSYSTFAEHVPSSSSSSIDKNDDIDDGATNRQFEGVEVIGALTLLEGHEDDIDDAAAAKCDEDGILSFDRPRSYDIDMSYTSSNDGQLEDVDVVNALNLLEGYEEGFNNDDDDSVEVETSGNNALECFNVILGRFATRCALDHWKCMTTKETEKCKQMQRQQACLQLLQTLLKVKVRHSLLLWSHSINRIAWQENAVGAFRQRNLGNAFRSWRDVTKASKMRRQVYFLMMIFNRWRVLTEESVATRQKKYAALMHWAERLTRKSFSVLKVHAVSQREEREHSRGSYQPRHLFRSSLRSPEQSFANSTPDYTNQLSFRKSAQVPRFSDQESRYRGSGFASSRESFTTAFQSISPSARTNKHRFQELGSSRTASHSSSYHSTGRRSISSEMLHNSRRMSLSQPYSSHPTGTSQDDQDKFAIPFGCAADDIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YNK4</accession>
    <name>A0AAD8YNK4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PTM/DIR17-like Tudor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000519</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YNK4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047365">
        <property type="entry name" value="Tudor_AtPTM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21743">
        <property type="entry name" value="PTM_DIR17_Tudor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PTM/DIR17-like Tudor" evidence="1">
        <location>
            <begin position="88"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="168" mass="19387" checksum="CC3817363762806A" modified="2024-05-29" version="1">MGKKRDLMTVEERPMECILCLHSAGYHAMHPLYDTCGKEGRQYVLKATKSGIGGNQEVGMGSYVMCTNVDSDQGIFVWIGGQKYKVGTNIYKEFPDEQTGYHRFFKGEVKRFDTKRKFYKIVYEDGDKEEMTESQVKKYLQNPTNAATTKKAQSLLLWLHEIFVSMRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3V4</accession>
    <name>A0AAD9D3V4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016601</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000060">
        <property type="protein sequence ID" value="KAK1732702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3V4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="431"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="327"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="434"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="486" mass="54301" checksum="BD56B24DC55D7654" modified="2024-05-29" version="1">MAILDHQLTVARTGTTPTPAKDLIFIYKGGRAPEHVTHVRIDKSFDKIDDGAFEYCISLESIETHNWIRRVGKYAFHRCHSLKRIKLPGVTEVDEGAFWGCTSLTELEFGVGLQRIGEGAFSHCTLKRLVIPSRVSIEKCAFIDCAELTDVELSGGFDSIERGAFFGCRSPLRLKISGITIINEEFIGSSGISDAEFSEELELVRANAFSRCASLKSMVMPSVTAIEKYAFSDCTSLKSMKMPSVLTIGAYAFNNCEELTDLEVPVDFELMEKYAFHKCHSLKRIAIPLKDGVISDNAFTECEELSRVDLVGDVHNTISTFGLESSRDEMKKEMNQINLDLLQIKRDRESARIDNKDVSDITKSIQRWIKSTLEKYTKLEAQHSKLLKEAVKGAQKQWLSLFSGLTTDNDEFITTKGKVMLQLRETVVSTTADAPHELSKKDIRKKKTEEENAKKAAAKAQQDMMGGGFLSRLAAGVPSLEKKDLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3Y6</accession>
    <name>A0AAD9D3Y6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000054">
        <property type="protein sequence ID" value="KAK1733046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3Y6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="195" mass="22139" checksum="9E6045A48113DD92" modified="2024-05-29" version="1">MAKPISLKLSCIRLPPQKQYNTPEELMKLNSIETPEDAPEPSQLSKREKKQLQNKLNSNDPAIAKVLQAIQSGDAGFTRMADPEYKRGVKEFTQPPLNAMLPAEYKKMFKNCYELSNHPKAMDAIKMINMRRAAKQRLMTIHPECLQPNGAIAVPLDSEFMRLQENIENKIRGDGGLAFVFKRLDELGLYVNPIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D485</accession>
    <name>A0AAD9D485_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_016129</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000053">
        <property type="protein sequence ID" value="KAK1733152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D485"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="37"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1733152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="257" mass="29015" checksum="B89B035E814A44CC" modified="2024-05-29" version="1" fragment="single">CQRDHRPQHKRPCKKRAAELHDEILFKQPESSHKGDCPICCLPLSLDQTKSTMMTCCSKVICGGCYHSYKVRIFEEKLEQTCPFCRHPAPKSEEEEINNVLKRVKANDPVAMVQMSLRRYEAGDYDDAFRYVKKAAEFGDAGGHYELSIFYLEGPCVEKDEKKEVYHLEQAAIGGHPKARHNLGCKEKKNGRMDRAIKHMNIAAKLGHDVSLDALKVCFRGGLVSKEDFAAALRAHQAAVDATKSPQREAAEEARKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4M7</accession>
    <name>A0AAD9D4M7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000047">
        <property type="protein sequence ID" value="KAK1733587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4M7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051024">
        <property type="entry name" value="GlcNAc_Chitin_IntDeg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34823:SF1">
        <property type="entry name" value="CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34823">
        <property type="entry name" value="GLCNAC-BINDING PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042220017" evidence="1">
        <location>
            <begin position="18"/>
            <end position="841"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="841" mass="91188" checksum="5AC5F2F90262699C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5M4</accession>
    <name>A0AAD9D5M4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NUBPL iron-transfer P-loop NTPase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_015497</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000044">
        <property type="protein sequence ID" value="KAK1733800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5M4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02037">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000808">
        <property type="entry name" value="Mrp-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044304">
        <property type="entry name" value="NUBPL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961">
        <property type="entry name" value="IRON-SULFUR PROTEIN NUBPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961:SF2">
        <property type="entry name" value="IRON-SULFUR PROTEIN NUBPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01215">
        <property type="entry name" value="MRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="486"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="486"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1733800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="585" mass="63196" checksum="B95366F96585AA8C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5S1</accession>
    <name>A0AAD9D5S1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thymidylate kinase</fullName>
            <ecNumber evidence="3">2.7.4.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_014705</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; dTTP biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thymidylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5S1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:dTMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006227">
        <property type="term" value="P:dUDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01672">
        <property type="entry name" value="TMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000679">
        <property type="entry name" value="Thymidylate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00165">
        <property type="entry name" value="Thymidylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018095">
        <property type="entry name" value="Thymidylate_kin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10344">
        <property type="entry name" value="THYMIDYLATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10344:SF1">
        <property type="entry name" value="THYMIDYLATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01331">
        <property type="entry name" value="THYMIDYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate kinase-like" evidence="11">
        <location>
            <begin position="16"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="227"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1734832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="252" mass="28044" checksum="D0A0AB8597D19EBE" modified="2024-05-29" version="1">MITTPGSPKRGAFILLEGVDRCGKTTQVSLLTRHLLNLSLATVAYRFPDRTTQVGGLINGYLQSSAEVGGVDDRAIHLLFSANRWEAAPKLADTLAQGSHIICDRYAYSGVAFTSAKREEDRSSMSGGELTLDWCMCPDIGLPAPDAVIFLDLEQEEAEKRGGYGGERYEKKELQTRVRSRFAELQSLDEKDGRVPWHVVDASKSIEEVHQELVSIVTNTIDRVQTESSPLQRMWADGEYELPEPNNEKEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D607</accession>
    <name>A0AAD9D607_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nucleosome assembly protein family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_015193</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the nucleosome assembly protein (NAP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D607"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.90">
        <property type="entry name" value="Nucleosome assembly protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037231">
        <property type="entry name" value="NAP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002164">
        <property type="entry name" value="NAP_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11875">
        <property type="entry name" value="TESTIS-SPECIFIC Y-ENCODED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00956">
        <property type="entry name" value="NAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143113">
        <property type="entry name" value="NAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="40"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="387"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="387"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1734190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="418" mass="46000" checksum="7184637F1F8C5FD9" modified="2024-05-29" version="1">MADEDNSTSAAPPADTAEAEASSAGADDVAVNDAAAAISSIAVEDASDDEANEAVPAPPQEEEDEVVPPPPAAAAYQFNFNPPPQPHLAAADPNNMDFANLNPSEINAQFLSLLPPCIHPRLDKLKSLSEDRTQLLEQYLVERAELEQKYNGLMKPLYEMRRDVVTGKCDGDIASNDTTGASNGEDQQEVKGIPQFWACAMGHIDLLAELITEEDVDCMEHLVDVTCDDFADGSGFELHFHFSPNDFFTNSVLTKRYEVPNLLTEDEPMLQSVTGTDIHWFPNKSLTHKTITKKQRKKGGPNAGQVRTIQKTERAESFFHFFTPPKMPELGDVVDEEEAEAMEEHFDHDYEMACAIRGSLIPNAVHWFTGEAMEEAMYGDEGMDMMFEDDEDDDVEGGLNPFPPPATGEGENPECKQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6B1</accession>
    <name>A0AAD9D6B1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arylsulfatase G</fullName>
            <ecNumber evidence="3">3.1.6.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014721</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.15" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000038">
        <property type="protein sequence ID" value="KAK1734473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6B1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033889">
        <property type="term" value="F:N-sulfoglucosamine-3-sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050738">
        <property type="entry name" value="Sulfatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42693:SF33">
        <property type="entry name" value="ARYLSULFATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42693">
        <property type="entry name" value="ARYLSULFATASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14707">
        <property type="entry name" value="Sulfatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="329" mass="36227" checksum="CFCD77B1031D4B0B" modified="2024-05-29" version="1">MDWILGGVMDALDEAGSEVSDDTLVIFTSDNGPWTAEQSCAGSKGPFKGTWLKEHVSDDCTACPSEYKPSPLPGQKRRCIYPGTNYEVMGVSCGEDTGLGSAWEANVRMPAIVRWKGGGVPEGKTSSEMVSTLDVLPTVLSMIGKDIPIGSEVDGIDVTDVFLGQAQSSSSSLPLREGEDSQNETNRRRSERAIFFWRDGFKTGPLPAPFGRFDVVAMKIGWYKLWFWTKSSHYNADEEVYHDPPLIFDVLNDPAEAYPLDPDKHDDLIRHALHLMSEHKASIEWSAPLTLARDPKYLPCVNVESGCRTRPLPLDLDGGGDSIDQAEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6M5</accession>
    <name>A0AAD9D6M5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014646</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6M5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="105" mass="12022" checksum="B0A031721A6CF5B2" modified="2024-05-29" version="1">MSRTDGRKLVAFAGTAIVGALGFATIYLPFMADRDKLRGLFEEGEQSIPEGARREIQAILKAERESQQRMDEVVQQQQQYEEAEQQIEKQKASPGSMWSNFRRKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6V6</accession>
    <name>A0AAD9D6V6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014156</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6V6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160532">
        <property type="entry name" value="Ava3019-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042171279" evidence="2">
        <location>
            <begin position="23"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="266" mass="28685" checksum="31F84A44F73E80F9" modified="2024-05-29" version="1">MTKMCWPYQLLTLAAIASVGSSFSPASSSPPPYTASLKSRPAAITPLCSSPPRPSSATETTTTSTSSSSFPTSDIFDATTTLTNYDQSQQQFIQSDGNQGMGGGLSALHHIQSLQPTTRTSLQQAITTLTNQAHSERATDSSKGRIMLGICASNAPEALGGLKSWVAQLTLPRGMLHGMDVDGVPIPVEELGSVYVKYSTGGAMTFREMRKSKRGFDALWRPGDALLEMYDGDFRGVYFSVELGDGVFRQFGVLPTDLFMEEEEDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D974</accession>
    <name>A0AAD9D974_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Presequence protease</fullName>
            <ecNumber evidence="4">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_010762</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D974"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013578">
        <property type="entry name" value="Peptidase_M16C_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055130">
        <property type="entry name" value="PreP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016">
        <property type="entry name" value="PRESEQUENCE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016:SF13">
        <property type="entry name" value="PRESEQUENCE PROTEASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08367">
        <property type="entry name" value="M16C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22516">
        <property type="entry name" value="PreP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01264">
        <property type="entry name" value="M16C_associated"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16C associated" evidence="3">
        <location>
            <begin position="653"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1738732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1222" mass="135353" checksum="211D94D226B1F10B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAB7</accession>
    <name>A0AAD9DAB7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_008942</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1739992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAB7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="15"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1739992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="203" mass="23109" checksum="569B38E1A4BAA892" modified="2024-05-29" version="1">MITDIVESQIELLCCAACGAAEADHVKLKKCTACYLARYCSVQCQRDDWQQHKRACKKRAAELRDEILFKQSESSYLGDCPICFLPLSLDSKAIMWSCCCKRICNGCNYSNMTREMEGSLKHTCAFCRLSFPTSQEEIELNIMKRVEVNDPGATQEKGWRLYNERDYKGAFEYYAKAAKLGDAEAHCNLACMYIGRALVLRKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAR4</accession>
    <name>A0AAD9DAR4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lysine methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008671</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAR4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF109">
        <property type="entry name" value="RIBOSOMAL LYSINE N-METHYLTRANSFERASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HMG box" evidence="2">
        <location>
            <begin position="11"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="1">
        <location>
            <begin position="11"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="319" mass="35705" checksum="AAFB690AEE39779A" modified="2024-05-29" version="1">MSSDARDPNAPKKPLTALDFYAQAARRKEDAAKDVTADDTQTQASSELYELEFNNLSDAEKATWYKLARRDKIRYKKEMATYEPPVDSSSGCRLLLMGRFFPFDSEGIPFADTTLTIKETQNSCHIGEDGGTGLNVWDGAQLLLRYIEKVPNIVKNKRVIELGSGCGIVGVAAAICGCKEVIMTDLAYALPLMRENVDINRVAWKDTDVVVSCKECDWFQPPPVDELLGHYDSKADVLLVADCVWLSSLIAPLLRTLKLYTTESTDVFITYQQRGKEAHDLFMEGIHNLFDVVDVDTLKEADLAKPDVFHLLHCKRKVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAT0</accession>
    <name>A0AAD9DAT0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009757</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAT0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="374"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="439" mass="47689" checksum="A08B7CC094CFEF73" modified="2024-05-29" version="1">MVSGMAASIRSSLESSTFDLSGHDATSIQSITHDAFSTPFPPLDQMIRITFVVGAGKLSRQKYDAKAMQILTAALRELDYVEDRGAGCSFDCAGCFKTQHDTGKNLFTVVVFPKVSGGGNASNNASGDANEEEEPLLPTNSPGYKIAVCSISTFQSLLSSQCPTYAQKRKCMECIEGLVELLQSIENKLMGGHPLDSAEQSLYDEIGELKEKLAYTQKEAAKHVDEGLLTVQEKEMLVEMNQKRIATLMKEKSSAAVAEKLKKALARKEYLQRLTDEKLSSLSSTYPPPLRHEGKLTPLRKKLLPLLALEGKAKGGFLTLAETRALTEKEEIESEIEHLEEASYGWFEEEDAFEERLQKSRDKFNAKYAKKSGGKASAKKTPAAGRSGGGGNSVNKWVLPGQKQTGGWEKAGGKKSSAKGKGGSVFSAMMLDDSSSDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAU9</accession>
    <name>A0AAD9DAU9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Mitochondrial carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_008791</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAU9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990542">
        <property type="term" value="P:mitochondrial transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045315">
        <property type="entry name" value="Mtm1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45760">
        <property type="entry name" value="FI19922P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45760:SF2">
        <property type="entry name" value="FI19922P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="101"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="199"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="315"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1740696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="404" mass="43187" checksum="CFDDDBF6BF03A234" modified="2024-05-29" version="1">MAARPISPSPPVRSDAGRSSKGSASQSSSLLSRIISGSTGSIIYALSGTPIEVVKIRQQTAPREDSFSSSLKRQGNPVKKLLRSRGAIVLNNGLMLPIDAFPCLVAPGGGGVSKMDYSIYSRLFESCRTASSIVQEQSSGTFRMLKTIFRNEGVAGLYAGLKPTLAMSIPNTVLYLSSYDEISERLHAMHSSNSNVDASRAYIPLVAGSTARIISSFATAPLELIRTRQASIIAGSIPQGRAPGILEEFRLLVRTGGLMSCYNGLGPLLLRDAPFAAIYFLCLEQFRGSLSDNTSLGRWSGRHYTDQGVQIPASIDVMHTFAAGASAALVATALTGPFDVVKTVRQVSNGGNANTLSCIRQIFRDEGVKGLWRGNVSRMIKIVPGHAAMITCYEFGKRVFDGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DB76</accession>
    <name>A0AAD9DB76_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sphingosine kinase</fullName>
            <ecNumber evidence="3">2.7.1.91</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009968</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.91" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DB76"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008481">
        <property type="term" value="F:sphingosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050187">
        <property type="entry name" value="Lipid_Phosphate_FormReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358:SF31">
        <property type="entry name" value="ACYLGLYCEROL KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358">
        <property type="entry name" value="SPHINGOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="2">
        <location>
            <begin position="171"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="463" mass="51460" checksum="B9A534048823B4EE" modified="2024-05-29" version="1">MANNPTWPAAAASRIRIKITNDSYCRLFYNRSTGSINLVPLTADDASAITTASHAEIYDHSQTSANVEQDPLYQSYLSQSKDDSNQIIVDSFHPDDVIGANLSGGNGPKSKSGATFVYETMVKPMLEQAGVEHDKLATNHGGHAKERMELRKSTSDDNDNNGEERGDCIDSELKDISEYDAIIAMGGDGILFEIFQGIHARSMDEAQILSKLKFGIVPCGTCNGLAKSILHWSDNAEYTPMESVFQICKGHTARLDLASYQLAKTEKTYTSFLSFSWGLIADCDLESECLRWLGALRTDIWAVYRGILFPKKYRARFSYLPLSNKTNNGSASTKIDLPKLNEPLPKDWVTIEDDFSVFWVCNTTHASYNVFTCPMSKMNDGVFHVLIVRSSVSRLRLLQMLLKLETGGHIECEGLEIISCLAYRLEPLSDNTYNDLDGELIEGGTIQARLFNTAQFFAGKVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBF8</accession>
    <name>A0AAD9DBF8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Exocyst complex component Sec15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_009409</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBF8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090522">
        <property type="term" value="P:vesicle tethering involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.670">
        <property type="entry name" value="Dsl1p vesicle tethering complex, Tip20p subunit, domain D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007225">
        <property type="entry name" value="EXOC6/Sec15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046361">
        <property type="entry name" value="EXOC6/Sec15_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042044">
        <property type="entry name" value="EXOC6PINT-1/Sec15/Tip20_C_dom2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12702:SF0">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12702">
        <property type="entry name" value="SEC15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04091">
        <property type="entry name" value="Sec15_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exocyst complex subunit EXOC6/Sec15 C-terminal" evidence="3">
        <location>
            <begin position="975"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="515"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="638"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="842"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="47"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="83"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="642"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1739650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1267" mass="137873" checksum="9E850FEFD8E77E45" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBX5</accession>
    <name>A0AAD9DBX5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6824 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009138</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBX5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049227">
        <property type="entry name" value="DUF6824"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20710">
        <property type="entry name" value="DUF6824"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6824" evidence="1">
        <location>
            <begin position="19"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="271" mass="29946" checksum="E66F7C367ED71CEB" modified="2024-05-29" version="1">MSGSSSINSDCIIKLTHTDVLLGRGVGTNRRAGNTYFREVVNQHVEEYLASTKTHKMEITRSVIDRIHALNPPGRFLEKDEVWGGWRECEMKRAHEKTAQALRDGAARLRTSSKRSISSDAMITAQLSRPAKKQRKDVEVNNLDDVSVGSAEPVIKVNLPMKEEEEEEEDIEALITGLYSPIFSSATSVVDSAAVSPPCPISPCPSANSSVSQVNRKDSFDGTFGGLPFHIVDCNCLENDEFDIAPLEDVVSLDGMVDMQDEDIFRLWLTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCA3</accession>
    <name>A0AAD9DCA3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Rhomboid family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_008570</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCA3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066:SF1">
        <property type="entry name" value="RHOMBOID PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066">
        <property type="entry name" value="RHOMBOID-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="447"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="472"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="581"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="603"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="648"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="682"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="10">
        <location>
            <begin position="302"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="540"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1740475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="777" mass="87153" checksum="0E5EFCBF02EB6770" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCC5</accession>
    <name>A0AAD9DCC5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA pseudouridine synthase</fullName>
            <ecNumber evidence="6">5.4.99.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_008645</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCC5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050343">
        <property type="entry name" value="RsuA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00093">
        <property type="entry name" value="pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47683">
        <property type="entry name" value="PSEUDOURIDINE SYNTHASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47683:SF2">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041910555" evidence="4">
        <location>
            <begin position="23"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="5">
        <location>
            <begin position="161"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="64"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1740550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="371" mass="41277" checksum="45283343D6BB6717" modified="2024-05-29" version="1">MKAIISTMLSTMFLLRPSSVRGLSTFASCSSSRYLLRTAPTQLSRTYDVYTTGTSAAITKTNGGVLMSMSSSPSSSSETRKKKTPKKKMGVQRIDKVLADRGVGTRSQTFEIAKGKRITMASHPDAPHEERTRIKGPKEKVPPDAALFLDGNLLPSAAPLLLVYHKPKFVLSVMEDDKKYKDQERKHLGQVLSARYKRCGMHPVGRLDYDTTGLILFSLEGKLTQRLLHPKRGVEKEYVATVQGKADEEKLKQMLSDGVETTDGTFSAQLLEVTPSDGPASAPADDEMLWDEESSTEDRAQMDYSGEHSDVRLIVTEGKYRMVRRILANCGHPVVELRRERHGKVTLGDLAVGEFRDLKDEELEWAESLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCI7</accession>
    <name>A0AAD9DCI7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Mif2/CENP-C cupin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_008838</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CENP-C/MIF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCI7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019237">
        <property type="term" value="F:centromeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051315">
        <property type="term" value="P:attachment of mitotic spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051382">
        <property type="term" value="P:kinetochore assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051455">
        <property type="term" value="P:spindle attachment to meiosis I kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028386">
        <property type="entry name" value="CENP-C/Mif2/cnp3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16684">
        <property type="entry name" value="CENTROMERE PROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16684:SF11">
        <property type="entry name" value="CENTROMERE PROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="509"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="71"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="143"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="226"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="303"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="331"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="352"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="363"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="400"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="511"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="534"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1740743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="736" mass="81556" checksum="F2846B42E3E8F1EA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DD56</accession>
    <name>A0AAD9DD56_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Altered inheritance of mitochondria protein 24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DD56"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.160.10">
        <property type="entry name" value="Mitochondrial biogenesis AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002838">
        <property type="entry name" value="AIM24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036983">
        <property type="entry name" value="AIM24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016031">
        <property type="entry name" value="Trp_RNA-bd_attenuator-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00266">
        <property type="entry name" value="TIGR00266 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43657:SF1">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 24, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43657">
        <property type="entry name" value="TRYPTOPHAN RNA-BINDING ATTENUATOR PROTEIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01987">
        <property type="entry name" value="AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51219">
        <property type="entry name" value="TRAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="346" mass="35859" checksum="848989125FE9EA5A" modified="2024-05-29" version="1">MSNALISNSLSVVRSSGRSLLRRGSISRTQSSYLRSNTSSSHLTSIPCIYRAQSTTTTSSSSIQPRQDALTSSDGVIGVPIDFDTSSSIEGKESQIVTIRLEKDQVLRAESGAMMYMTDGIQMNTTTGGGLSAGFKRMLTGQSVFISDYTYDGTAGPCGYVALGTDFPSKIVRIPLQEYGGKIICQQGALLCASHTVDINIEFTKKFSAGFFGGEGFVLQGLSGTGDALVKAGGALIRKDLREGEKLKISSGCLVAFQAGVEFDVEQVSGFKNVIFGGEGLFLTTLTGPGAVWLQGQPPQRMISEIARRVPSGGGIGLAVPIPGMGGGTGDGGGEGGGESTGSAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DE41</accession>
    <name>A0AAD9DE41_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_004799</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DE41"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="3">
        <location>
            <begin position="63"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="1">
        <location>
            <begin position="63"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="29"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="185"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1744266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="382" mass="43737" checksum="10DEF378E93D9EB7" modified="2024-05-29" version="1" fragment="single">MCNTTTRLPNQVVSAPFRRLNSNNYLKEAPQQPIKSEPPCESVPSTPAPSASTFSNGEVPKKPMRPLTAYHIYFQIEREFIIQTLSGEDADKSIHEGKKCLDDVPERYINTKLSPDWYFGPGKRAKRKHRKQHGKIGFLELSRVISTRWAKLVETDPDIKQFVSKLAKQELEVYQREVEEYKELTKDMVPSAAPAKTTAKKSKKRKQSEQSQQQEVAPAASMMRMMPQHQMMASQPTPEMIASYQRTFYGAASQPIEDKSFMNNSVQLRQEINQLKNEIEYVNSCITKYSHHFEGQPTPTFTQTTDSAPPKKQFYRRQSSNISISIFDSVMDESGKVEPKTKKTKKSFYRRQSSDMSLSFLDSIMEEAGKNKSSSKKTKKSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEK9</accession>
    <name>A0AAD9DEK9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_006502</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEK9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1742905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="240" mass="25608" checksum="D2A25F4A8A261A1D" modified="2024-05-29" version="1">MSPARAGTPPVISVNRSGALDAEDALSVQSQIDAKALASTAARDRVKLQLILASLSKSADGTEVLDVGPTNPSLSHAYGAKAAQRNEIYGNVWSTVHKKLQRSMNKIVAGVNLGCRDKMLLMFLSTSNWLDLSMGDFDTLDEVASAKKGAFVSMLLPDSNAMQITRRRLAGVPDSQRNALLLGDAPKNVGKTDQTLNVMTVVEDMTSILGLGGNIIAFCRTGRAYDVEKEEGAILRSCTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG57</accession>
    <name>A0AAD9DG57_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein arginine methyltransferase NDUFAF7</fullName>
            <ecNumber evidence="7">2.1.1.320</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_003093</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:48108"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:88221"/>
            <dbReference type="EC" id="2.1.1.320"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NDUFAF7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.320" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DG57"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035243">
        <property type="term" value="F:protein-arginine omega-N symmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003788">
        <property type="entry name" value="NDUFAF7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038375">
        <property type="entry name" value="NDUFAF7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049:SF5">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02636">
        <property type="entry name" value="Methyltransf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1746486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="421" mass="47261" checksum="6DD2EE8CBCA84138" modified="2024-05-29" version="1">MLLRKYICRRLLEYYSQPAHKVVGTPDASVDFSSLLGQWHWKRTYKQLYKQQKGMWLTPVELFAPYYSNVFANFVSSSMKPMLESKKHNSDGFQIVELGGGRGTNAKALLNHLQLHHNDVYDRLTEYTIFDTSPTLHELQRQNLKIDSDHADKINLVNVDMMEIAEGTSPFLTHSNIPTTLIALELLDNLPHDKIAKCFETDEILQAELIPLDDDCTTSGASSEAIIDTSKQYHEEFSPASDPLLQNILSIDPSLSTRLASSGPRWIPSVALGVLMRLFECRPNSAVAFADFDWLPPPDLSTPEDQSLILAAEPALGDPIVTDMKGIDHPCYLTSPPDALCDILFPTDFARMASFTKSILRRDNERRAMPVSVAAMKQNDFLLQYGLDEVNKTKSWAGYSPLINDFGNCSVLTVTPHHLCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DH54</accession>
    <name>A0AAD9DH54_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003589</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DH54"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="361" mass="40406" checksum="ADB3B861B4187032" modified="2024-05-29" version="1">MSSHIFWSNVNVMNTNNIIAIVATSLLCIASVPSVLSFGGYVVTSNNGNNVAARNYHKCWRAQQQDMMCHRRFGLTDGVRLRHNVQLQMAADESTNDGVDNNELRVSKRKRLLNVFRRVFRRRSTEQQEDELEEEEESISITITEDASIELTDDNAEEDEILEVEAPSSITEDIAWKGDGDNVDDDIVSSSTTTNTTTPTPISSTRQATASPNTDLSGTWAPIVTPSFKSEYDDYLKNFIVNGIEYQRETIRQLDNGQSLEIIAQNPAGNWNRTLIASDSSNPLNTTIVDPDKDTDDGTKHKSLLRGKPRVKGGVFETVRYLDVEDADVLVCESKFLPSEFESSSSSFKYGSVLWKFRRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHX9</accession>
    <name>A0AAD9DHX9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1</fullName>
            <ecNumber evidence="4">3.6.4.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_000390</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHX9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45766">
        <property type="entry name" value="DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45766:SF6">
        <property type="entry name" value="SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="59"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="389"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1748451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="564" mass="63224" checksum="E05A2DB3C3E95C47" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIK2</accession>
    <name>A0AAD9DIK2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_001442</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIK2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050189">
        <property type="entry name" value="MFS_Efflux_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43124:SF3">
        <property type="entry name" value="CHLORAMPHENICOL EFFLUX PUMP RV0191"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43124">
        <property type="entry name" value="PURINE EFFLUX PUMP PBUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="325"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="356"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="456"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1747479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="699" mass="77098" checksum="76F65CA4EAD54299" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJ80</accession>
    <name>A0AAD9DJ80_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJ80"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="82" mass="9353" checksum="2B8DCE81D99210F7" modified="2024-05-29" version="1">MRWSNIRDRADDAVVGGSTVESSRTSACQSMSSSEKTGVNYDKELIELPKSTHIDRDEGRRRFSLFRRRRTNPDVENMSASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DK81</accession>
    <name>A0AAD9DK81_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase (GlcNAc)</fullName>
            <ecNumber evidence="3">2.4.1.229</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001203</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.229" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DK81"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033830">
        <property type="term" value="F:Skp1-protein-hydroxyproline N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021067">
        <property type="entry name" value="Glycosyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34496">
        <property type="entry name" value="GLCNAC TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34496:SF6">
        <property type="entry name" value="GLYCOSYLTRANSFERASE 2-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11397">
        <property type="entry name" value="GlcNAc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="182"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1749264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="983" mass="109814" checksum="E96071689DB7A901" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DKG6</accession>
    <name>A0AAD9DKG6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heat shock protein 90 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_001024</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DKG6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="124"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="131"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1749085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="261" mass="29946" checksum="A08DB2119D31B84A" modified="2024-05-29" version="1">MKALKESETNDISQIGMFGVGFYSTFLVADRVSVASKHNDDDTQNVWESLNGEASFHVGPDPRGNTLGRGTEITLHLKEDAEEYLSPYKLKEMIGHYSEFVTHPVSLRQIKTIQVPKERMNLMKKRKKEGDGDDIEVSDEDEAEEKEPEMEEVTTYEYEQINTDPAIWARDKDGITDEEYQEFWKVVSKGDSAGDAEDWTHFNAEGNINFKSILYVPSEVPFALQQGNMEMMKPGLRLYVRKVLISDEFDLMPRYLNLSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRN1</accession>
    <name>A0AAD8XRN1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Photosystem II reaction center protein K</fullName>
            <shortName evidence="9">PSII-K</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">psbK</name>
        <name evidence="11" type="ORF">QTG54_017203</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="11"/>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">PSII is composed of 1 copy each of membrane proteins PsbA, PsbB, PsbC, PsbD, PsbE, PsbF, PsbH, PsbI, PsbJ, PsbK, PsbL, PsbM, PsbT, PsbX, PsbY, PsbZ, Psb30/Ycf12, at least 3 peripheral proteins of the oxygen-evolving complex and a large number of cofactors. It forms dimeric complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Plastid</location>
            <location evidence="9">Chloroplast thylakoid membrane</location>
            <topology evidence="9">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the PsbK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRN1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009539">
        <property type="term" value="C:photosystem II reaction center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00441">
        <property type="entry name" value="PSII_PsbK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003687">
        <property type="entry name" value="PSII_PsbK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037270">
        <property type="entry name" value="PSII_PsbK_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002715">
        <property type="entry name" value="PRK02553.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35325">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35325:SF1">
        <property type="entry name" value="PHOTOSYSTEM II REACTION CENTER PROTEIN K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02533">
        <property type="entry name" value="PsbK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161037">
        <property type="entry name" value="Photosystem II reaction center protein K, PsbK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="7 9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 9" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="11" id="KW-0934">Plastid</keyword>
    <keyword evidence="2 9" id="KW-0674">Reaction center</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="propeptide" id="PRO_5041757128" evidence="9">
        <location>
            <begin position="1"/>
            <end position="7"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041757127" description="Photosystem II reaction center protein K" evidence="9">
        <location>
            <begin position="8"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1732160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="44" mass="5024" checksum="20A8A7414D2653FA" modified="2024-05-29" version="1">MESLLLARLPEAYVVFSPLVDLFPIIPLFFLLLAFVWQAAVGFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSH2</accession>
    <name>A0AAD8XSH2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sel1 domain protein repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000055">
        <property type="protein sequence ID" value="KAK1733014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSH2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="117" mass="13103" checksum="7B492C777FBC297E" modified="2024-05-29" version="1">MYNLGGYYDTGRPSIPKDQAMARVWFQRAAEKGESRGAYNLACSYRDGEGGAVDKAQAAKYFRMAGERGHIQGVTCYGLALMSGDGIKRDIVEGKKWLKRELMRGMNLQYSNCKCMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XT44</accession>
    <name>A0AAD8XT44_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sel1-like repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_016140</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000053">
        <property type="protein sequence ID" value="KAK1733163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XT44"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="7">
        <location>
            <begin position="17"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="79"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1733163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="309" mass="34510" checksum="70DF8F51644ED473" modified="2024-05-29" version="1">MSETNAAEADDVMMCRCASCGATEADDIKLKTCTGCKSARYCSIKCQKEHRSQHKRACKKRATELRDEVLFRQTEGTDCPICLLPMPLDPDKLAMISCCGRKICAGCEFANALREIEEGLKPTCPFCRLPAPRDDEKTFEVNMKRRAEVDDPAALQWMGVECQQKGDYSGAFEFWTRAAELGESESHYQLSVMYHGGYGVEMDEKKKIHHLEEAAIGGDIVARVNLGVLEQGNGRFERAEKHFTIAANLGCEDAINKLRHLQLRGFMSYEDLDTVIHSHQAALDAMKSSQREAGEANLRRAAREGGYDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTE2</accession>
    <name>A0AAD8XTE2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015926</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000050">
        <property type="protein sequence ID" value="KAK1733367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTE2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="165"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="241" mass="27035" checksum="4CD3C251401C436C" modified="2024-05-29" version="1">MEPPPIPSVLLRGEWSMGKVLEVYWRFSMIGDTYLGRCLAGLMPEKPNFGILPPHFTAGRENPFIEEGMKRCFGVILRRYGGFGVEGALLLFLASIVYHHEWLKTQIAGTTDHPFLQIPILNDPKLLEELKKLVTLDPAGAVTMATGVPESVKLRDKLREVIGLLTEYRNDVKWLKENLTEMVKNAMEEKATENGNITATFVAEQVAAATSKLAAPLVKQMEEMEQDLLLLLGHAHRVLWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTQ2</accession>
    <name>A0AAD8XTQ2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015556</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000045">
        <property type="protein sequence ID" value="KAK1733701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTQ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22895">
        <property type="entry name" value="ARMADILLO REPEAT-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22895:SF0">
        <property type="entry name" value="ARMADILLO REPEAT-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
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        <location>
            <begin position="11"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="165"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="369"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="609"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="166"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
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            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="615"/>
            <end position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="632" mass="68562" checksum="B48C5B404532347C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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    <name>A0AAD8XU98_9STRA</name>
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        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="5" type="ORF">QTG54_015569</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
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            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000045">
        <property type="protein sequence ID" value="KAK1733714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:GTPase activator activity"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
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        <property type="entry name" value="LRR_dom_sf"/>
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    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="271"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1733714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="308" mass="35234" checksum="0703777DD3A07F65" modified="2024-05-29" version="1">MDLEHLTLQRCDINDEGLQALTEGAVTHCKDLNLSGNDSITASGLRYLSTSLQSDTCHLESLLIGSINLRDDGAEVLARGLIGNQFLKCLHLCQVTPFTPAGWNAFITALCDTSSVNNTYLSNHTFHEFYMSNYEEGFDIDESVVLYLQLNKEHPEHAARCKILMNHAHLNMAPLLQWELKFLPLAVGWFERAKPCVTLSIQEKFPNPRRRVLDESEEVFQSRILTSVYEFVRGMPKKVLERRDELALAAAYDEKIAMVGDESNRILRILKKRLREDVEERDRKITKLEEENKRLRGIVDSVRNSLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUI9</accession>
    <name>A0AAD8XUI9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015688</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
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            <taxon>Sar</taxon>
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            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
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            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000046">
        <property type="protein sequence ID" value="KAK1733645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
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            <end position="82"/>
        </location>
    </feature>
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        </location>
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        <location>
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            <end position="610"/>
        </location>
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            <end position="637"/>
        </location>
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            <end position="652"/>
        </location>
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        <location>
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        </location>
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        </location>
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            <end position="714"/>
        </location>
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            <end position="737"/>
        </location>
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        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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            <end position="825"/>
        </location>
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        <location>
            <begin position="866"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1041"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
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            <end position="1111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1189"/>
            <end position="1217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1309" mass="146219" checksum="3D1EBB37D6BB7D88" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUN7</accession>
    <name>A0AAD8XUN7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_015451</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
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            <taxon>Sar</taxon>
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            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUN7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052420">
        <property type="entry name" value="Espin/Espin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153">
        <property type="entry name" value="ESPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153:SF8">
        <property type="entry name" value="FORKED, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="195"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="195"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1733924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="220" mass="23747" checksum="184CC1C636DA38F4" modified="2024-05-29" version="1">MTTSNSKVLNSVYLLGLILDNDWKMIRTLIAVSSPDYFRGMTVSMHKLNGMTFLHVIVRDNPPLDIVGNIIKLCPEMAAARDGLGRTPLHIAAGSKVSPLLLKLIARAYPAACDAQDEDGRTPLHFVCDTSFVLFSDNDPSQKASQHEAVVALLSESSYASTIEDADEMSPLEYAIMCGASLKTVQLLQASATKSLQSRARSASPNPGPGANKRRRVSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV06</accession>
    <name>A0AAD8XV06_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015442</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV06"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="76" mass="8722" checksum="E822A5F23E941FD3" modified="2024-05-29" version="1">MSTEINYLKSSLQEKEDAISKMGASVQGDGVAKEEKEQVFAELMFLSKSFQELESSLETNRQNYEECIQSLRKRQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWQ4</accession>
    <name>A0AAD8XWQ4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014149</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWQ4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="375" mass="43318" checksum="E4A8043DEB9D5F35" modified="2024-05-29" version="1">MESPHLNKTVTTDEERPDDNYNFSQPTTILLTLVVIYIICTAIWFIHSRYCSANRKGPTFLSALRQRLALWKGSLFRNNRNSHYNDNNLPSHYDLDEREYKSWSVTDVASWSRSKLAVTQLQSNGNHHYNNSPYFRNNTSTTQYHESNHEYDMIIQQAIYALMQQQIDGASLDYITLEYLSRWMPFGTAVRLMSQYDALLTTYSSQEGNNQENHTGWLSEDLPSWYSDNQLHQERNNHHDVEAPDALNSEHVQRLMKDRFGLTLPALRTEEKLPSDTKVASALEMTSRATPIRVTQTKKPAVNNSTNLDDILKSMPPHIRAVAERRSDLVADLLASRQQQQQPLIPIHEEHLTGESEEEADLDSESASLLRRRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XY36</accession>
    <name>A0AAD8XY36_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_013721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XY36"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1735558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="280" mass="31597" checksum="5A100E54B407556D" modified="2024-05-29" version="1">MYEIFGQNLSRCCTELEELSIVNTGIVRGENTPMYSVGLASALVSTLKRRKDMIRKFDYEVYGRPLLFNRFGVGANTDIIRKTNCDVFSAVLQSTKLEQLCIKCSAGPYRDLVRAATICKAENGSREKKSSSIRDLSILCLETRECNGNYIMHPVGPLLDHFSDCKCLQTLYLTLPKPCWRESQTLEALTNLLTNKPELLRVGLSFSGLDDREGKVLEYLSGILAQLALGSVNIFDFGGLLNVDEARLLKLIQGMEKLGFDVRRNRLHAAIRFQRSERRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYC5</accession>
    <name>A0AAD8XYC5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cyclin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_013414</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYC5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000093">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02984">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0195">Cyclin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="2">
        <location>
            <begin position="38"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin C-terminal" evidence="3">
        <location>
            <begin position="205"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1735708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="308" mass="34947" checksum="900319B253F546E2" modified="2024-05-29" version="1">MQPTDILSRDTVAVADTLAAMIKREQLTTSSWHWHDDGYLDPSDPTIITADDRKKLVDWCYHFVDHCQLSRVTVASAMEMVDRFLSITSTSISNSADADATTVRTVSDEALRDQSKFQLLTVTALYVAIKVNERVALSSDLFAEMCSQVYTTEEIEDMERVLLSGLSWRCHAPTAHQVGLSILSLILPYVDIPEASWGFLMDEMKYLIELAVLDYYFSTQRTSTVALAAIYNATGDMRSKEHRERLRAFLSVIMECFDFDHSKQVSEVRRKLQSLLLQDDDVDERSLDEGSVDLDDSVKTCRVSNRLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYY9</accession>
    <name>A0AAD8XYY9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SGT1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013079</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYY9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010770">
        <property type="entry name" value="Ecd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13060:SF0">
        <property type="entry name" value="PROTEIN ECDYSONELESS HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13060">
        <property type="entry name" value="SGT1 PROTEIN HSGT1 SUPPRESSOR OF GCR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07093">
        <property type="entry name" value="SGT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="649"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="760"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="659"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="671"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="898" mass="100296" checksum="82A209BAF3647175" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZF4</accession>
    <name>A0AAD8XZF4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cationic amino acid transport permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_012569</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZF4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029485">
        <property type="entry name" value="CAT_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43243:SF82">
        <property type="entry name" value="CATIONIC AMINO ACID TRANSPORTER C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43243">
        <property type="entry name" value="INNER MEMBRANE TRANSPORTER YGJI-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13906">
        <property type="entry name" value="AA_permease_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="143"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="255"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="299"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="352"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="407"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="437"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="468"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="497"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="Cationic amino acid transporter C-terminal" evidence="6">
        <location>
            <begin position="472"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1736547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="535" mass="57451" checksum="F82D274865FEE1D6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZG0</accession>
    <name>A0AAD8XZG0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thioredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_012893</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZG0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000245">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="30"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="33"/>
        </location>
    </feature>
    <feature type="site" description="Deprotonates C-terminal active site Cys" evidence="3">
        <location>
            <position position="24"/>
        </location>
    </feature>
    <feature type="site" description="Contributes to redox potential value" evidence="3">
        <location>
            <position position="31"/>
        </location>
    </feature>
    <feature type="site" description="Contributes to redox potential value" evidence="3">
        <location>
            <position position="32"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="4">
        <location>
            <begin position="30"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1736293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="103" mass="11511" checksum="8D9780D579273B28" modified="2024-05-29" version="1">MVKYVESEGEWMALMNEEKLVVVDFTASWCGPCRMVAPHFEALSKEYTNVIFVKVDVDKQDKITQMCGVQVMPTFQFFKGGQKVDELKGADVATLKSKVAALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZQ4</accession>
    <name>A0AAD8XZQ4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZQ4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="129" mass="13527" checksum="8DB04ED22929808A" modified="2024-05-29" version="1">MYQNAPPQGYGGGPPSSQQQYGGYPTYPNRQYGNTYQQPATGATADAATAIATNNNNSTVNKPTTTTTTTTAAVVPSPPVSSDSPSANPWASSSNQHPTHTTPPNNGEYESATYPAPERHSSRATPSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZW1</accession>
    <name>A0AAD8XZW1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutathione peroxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_012431</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glutathione peroxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZW1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00340">
        <property type="entry name" value="GSH_Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000889">
        <property type="entry name" value="Glutathione_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029760">
        <property type="entry name" value="GPX_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003582">
        <property type="entry name" value="ShKT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592:SF132">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE 7, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00255">
        <property type="entry name" value="GSHPx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01549">
        <property type="entry name" value="ShK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01011">
        <property type="entry name" value="GLUTPROXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00763">
        <property type="entry name" value="GLUTATHIONE_PEROXID_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51355">
        <property type="entry name" value="GLUTATHIONE_PEROXID_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51670">
        <property type="entry name" value="SHKT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 4 8" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042061809" description="Glutathione peroxidase" evidence="5">
        <location>
            <begin position="24"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="ShKT" evidence="7">
        <location>
            <begin position="28"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="6">
        <location>
            <begin position="79"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1736986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="244" mass="27540" checksum="715BA3853812471D" modified="2024-05-29" version="1">MKTAFHFLYAALLILVSIPHSQGNLSYNVIEDKLEECADWAEQGECTKNPRYMEEKCPASCKWQASEDERTKKAIEEKLENIESFFDLEAEDIDGELLKFDQFKGKVTVIANVASFCGYTESHYKGLVDLYSQFKASAIGFNILAFPCNQFGEQEPNQCHSIKEFALSKGVEFTMMNKVDVNGSEASPVYLFLKKVAGPPRIIWNFATYYVVRPDGTVNSYSGVEPTELKDVILEAMGMDKDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y039</accession>
    <name>A0AAD8Y039_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Replication protein A subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_013071</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the replication factor A protein 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y039"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04474">
        <property type="entry name" value="RPA1_DBD_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04475">
        <property type="entry name" value="RPA1_DBD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04476">
        <property type="entry name" value="RPA1_DBD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04477">
        <property type="entry name" value="RPA1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000041">
        <property type="entry name" value="Replication protein A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000064">
        <property type="entry name" value="Replication protein A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000090">
        <property type="entry name" value="Replication protein A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047192">
        <property type="entry name" value="Euk_RPA1_DBD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013955">
        <property type="entry name" value="Rep_factor-A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007199">
        <property type="entry name" value="Rep_factor-A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031657">
        <property type="entry name" value="REPA_OB_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004591">
        <property type="entry name" value="Rfa1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00617">
        <property type="entry name" value="rpa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47165">
        <property type="entry name" value="OS03G0429900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47165:SF4">
        <property type="entry name" value="OS03G0429900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04057">
        <property type="entry name" value="Rep-A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08646">
        <property type="entry name" value="Rep_fac-A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16900">
        <property type="entry name" value="REPA_OB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Replication factor-A protein 1 N-terminal" evidence="12">
        <location>
            <begin position="3"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="OB" evidence="11">
        <location>
            <begin position="204"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="Replication protein A OB" evidence="14">
        <location>
            <begin position="311"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="Replication factor A C-terminal" evidence="13">
        <location>
            <begin position="467"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="145"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="426"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF16900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1736471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="629" mass="68041" checksum="2724E5AEB9012402" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y041</accession>
    <name>A0AAD8Y041_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012604</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y041"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF109">
        <property type="entry name" value="RIBOSOMAL LYSINE N-METHYLTRANSFERASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1736582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="356" mass="40410" checksum="CD863524EEEBF1B3" modified="2024-05-29" version="1">MQEPHPIASAFFASHDKTIESRRLDNDSSAQQRTFVSNIRNSIGWRTRFASATMHPVQITPVECRTLESDNSSPVKFHVRQVFPEHNQIKQASNLGTGATVWPGSIILLRYLEKLAHDPQQQNVLLGKVIADLGSGTAITSLASALLGARLVFCTDGCDPVVDLARQNIHSANLELTNTDESLKGTTIEKEDCQFDVRGCKIIAKRYLWGDSTLLQELPNDNEGNPMNTDTTQIDIILSADCIVPKLYPIKPLIDAIDELSGNETITYLSYEQRYYNEYNPSEEFRRLARLRNLKVEVVPSCELNEFYPANDIEIWKVSRYKINLEEEDQFDTEQKTKVSVSQEKNNHEALLWHMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0Q7</accession>
    <name>A0AAD8Y0Q7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0Q7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1736816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="98" mass="11001" checksum="B074270DE3DD707F" modified="2024-05-29" version="1">MCMWLIPSHHRTCGAEDRCRYALLTCRGGRGYLFIASVRSRILRGCRLIVLSRCIACSGLYIPRATIVCVCFDVSVWGGSIAIHIWGCICSGFEWGWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1C5</accession>
    <name>A0AAD8Y1C5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphoglycolate phosphatase</fullName>
            <ecNumber evidence="6">3.1.3.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_011662</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="4">Divalent metal ions. Mg(2+) is the most effective.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.18" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000024">
        <property type="protein sequence ID" value="KAK1737678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1C5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008967">
        <property type="term" value="F:phosphoglycolate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000039">
        <property type="entry name" value="Phosphoglycolate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006349">
        <property type="entry name" value="PGP_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01452">
        <property type="entry name" value="PGP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288">
        <property type="entry name" value="4-NITROPHENYLPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288:SF46">
        <property type="entry name" value="HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13242">
        <property type="entry name" value="Hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000915">
        <property type="entry name" value="PGP-type_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01139">
        <property type="entry name" value="C2.A:_Pyridoxal_Phosphate_Phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00039">
        <property type="entry name" value="phosphoglycolate_phosphatase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042000873" evidence="5">
        <location>
            <begin position="20"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1737678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="354" mass="37988" checksum="F8BA57738F4ED1BE" modified="2024-05-29" version="1">MHIARSSLSAALMATSVRAFSPAASSSFRSSAAISNLSSRTFSSTTSLNANVLKLTEPAKDLLPDVDVFIFDCDGVIWRGDSVIEGIPETLEKLRALGKKMYFVTNNSTKSRKGYKKKFDSLGLDVPAEEIFSSSFAAAAYLEQTNFKESGKKVYVVGEIGIQEELDLIGVPHFGGPEDGGKQPDMGPGGALPHDSDVGAVIVGFDRNINYYKIQYAQLCINENPGCEFIATNTDAVTHLTDAQEWAGNGSMVGAIKGCTGQEPTVVGKPSPLMIDYLCSKLGLDKGRICMVGDRLDTDILFGTDNGLKSLLVLSGVTTEEKLLSQENTITPDYYADSIVDFFVDENAKVEASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1H5</accession>
    <name>A0AAD8Y1H5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">cGMP-dependent protein kinase</fullName>
            <ecNumber evidence="4">2.7.11.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">QTG54_011540</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.12"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.12" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1H5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030553">
        <property type="term" value="F:cGMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004692">
        <property type="term" value="F:cGMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000068">
        <property type="entry name" value="cGMP-dependent protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF143">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00103">
        <property type="entry name" value="CAMPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0140">cGMP</keyword>
    <keyword evidence="12" id="KW-0142">cGMP-binding</keyword>
    <keyword evidence="10 21" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7 21" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="19">
        <location>
            <begin position="207"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="19">
        <location>
            <begin position="326"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="18">
        <location>
            <begin position="586"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="20">
        <location>
            <begin position="845"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="13"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="17">
        <location>
            <begin position="82"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="115"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="615"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAK1737768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="903" mass="102103" checksum="3FC16875EADCA9AF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1I0</accession>
    <name>A0AAD8Y1I0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sel1-like repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_011459</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1I0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="7">
        <location>
            <begin position="31"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="98"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1737687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="323" mass="35286" checksum="7D5E85D1B6B21367" modified="2024-05-29" version="1">MTNEDGKEGGIGVSTDTDIGKAGEIDMTSFCASCGIAEVDDIKLTTCDANNCKLVRYCSVACHREHRLQHKEECKKRVAELRDDLLFAQPESSNFGDCPICFLPLAINTKSNVLMSCCSKAICDGCSYANKIRGRRESLEQICPFCRHPVPATDADIDANRMKRVEANDPVALRRVGKTCYDEGDYGSACEYLTKAAGLGDVEALYHLSVMYKKGDGVEKDGKMAVYHMEEAAIAGHPLARFNLGIYEWNNGSMERALKHFIIAANLGDDKSVEILKKGYSRGLVSKDDFAAALRAHQAAVDATKSPGRDAAAAEKARRRNAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-06-18" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y244</accession>
    <name>A0AAD8Y244_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Multidrug resistance-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_011422</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
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</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y297</accession>
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                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        </source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAK1737710.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
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    <sequence length="303" mass="34240" checksum="48058536E1E6FDD2" modified="2024-05-29" version="1">MKKHSGKGTIAYDNGDTFEGEFDNNEPNGVGKMTYKDGRVCEGIWKNGKIEYEGELVDGKPHGRGKNMYPNGCVYEGEWENGVRHGNGRYEWNDGMSYEGEWRADKRQGKGISKYSDGTSYEGEWKDDKRDGEGISKYPVGSVQYDGDYKDGLPDGNGTCNFKNGNVYTGELRADYPHGKGVMTYANQDIYDGEWKAGFRDGKGTMKYHNEDVYTGEFGKGKMHGKGTYEYANGDVLKSIGEWKQGKKCGAFDDIIRYNKRVYYENDEVKSDPNVKREASWDEDTDTEEGPPSKRRNVSISRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2B1</accession>
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        <submittedName>
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        </submittedName>
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        <name evidence="5" type="ORF">QTG54_011837</name>
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            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
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            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
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        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.13" evidence="5"/>
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        <property type="protein sequence ID" value="KAK1737551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="F:ADP-ribose diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="entry name" value="NUDIX_NadM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43736">
        <property type="entry name" value="ADP-RIBOSE PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43736:SF5">
        <property type="entry name" value="NUDIX HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="Nudix hydrolase" evidence="4">
        <location>
            <begin position="133"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1737551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="329" mass="36250" checksum="0897766691DCF9ED" modified="2024-05-29" version="1">MVDNSGLIQRQTASSSSSSTSALPLVRSTTMDTTTTFRRRRTPHSSSNNIKSWMLITLASITIFMFGIFITIISQHKKQLKTAGSIYTKSNTNKLSNTAACPHGQERTWHGGHPAQDRPGSCWCGQDEYCMCTPSVAIDIVLYQKRPSTKNNPSDGADYDVWVVRRSDTNQLATIGGFVDTGETTENAVLREVEEETGITIPPQLMSSRHSGASSPNKNNSAIKLIGVYSDPRRDNRRHIVSIAYALEFNPDSMTTKYGSGIPHAGDDAKDVIAIPLEEIGVKYVGEDWYADHLSILLDFKMQLMVMKDGEVDRSKELYGGDVARSTCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y351</accession>
    <name>A0AAD8Y351_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010988</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y351"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042280276" evidence="1">
        <location>
            <begin position="20"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="198" mass="22058" checksum="ECDD29B545BF4C3D" modified="2024-05-29" version="1">MNAILLILLFLIIDANVSAASGRVHLRGKRAKFDKLDDPQDRTADAAEEDSICQDVDMDLVATKWNLTNFTWHGFPEPDGGEETLKPVAPERHGMTLLLEEDGFSGTCGNNLCWGVAEKIGDKMFWIHALARTKMTSTPQEEAYAAMLTNSPYIYKTCVDSATNHTNLHLFEVVDTDDDGNPKQGRLMAIYDQIQLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y470</accession>
    <name>A0AAD8Y470_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sulfate permease family inorganic anion transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_011019</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y470"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052706">
        <property type="entry name" value="Membrane-Transporter-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43310">
        <property type="entry name" value="SULFATE TRANSPORTER YBAR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43310:SF1">
        <property type="entry name" value="SULFATE TRANSPORTER YBAR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="469"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="7">
        <location>
            <begin position="515"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="603"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1738350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="683" mass="74786" checksum="485FF5DFC49FF9AD" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4Z6</accession>
    <name>A0AAD8Y4Z6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">NAD-dependent protein deacetylase sirtuin-1</fullName>
            <ecNumber evidence="9">2.3.1.286</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_009553</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.286" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4Z6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017136">
        <property type="term" value="F:histone deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF9">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="8">
        <location>
            <begin position="1"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="126"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1739794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="208" mass="23341" checksum="7A6A15ECC5D9E30B" modified="2024-05-29" version="1">MFQIQGETFDKRLASVANLISQKKNIVVLYLFDLNAFSEDPRPFWKFVRTNNFASGKIAPSTSHLFLAWLDEQQTMLLRIYTQNIDGLEQSAGVDEDKIGLRASDVEAGVPICHRRIAKKGKISHNTAKTNSIEIPPERRSSRKRSSNNNGMAEEFYPPPVEQGCCGGIIKPNITFFGEKLDSTISRRLEEDYKKADALIVMGTSLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5A7</accession>
    <name>A0AAD8Y5A7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Nucleoporin SEH1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_009971</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat SEC13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5A7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035859">
        <property type="term" value="C:Seh1-associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037363">
        <property type="entry name" value="Sec13/Seh1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024:SF3">
        <property type="entry name" value="NUCLEOPORIN SEH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="30"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="11">
        <location>
            <begin position="535"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="11">
        <location>
            <begin position="606"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="9">
        <location>
            <begin position="535"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="9">
        <location>
            <begin position="606"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="335"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="474"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="583"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="690"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="345"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="521"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="583"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="698"/>
            <end position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1739428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="788" mass="87532" checksum="0F6FAF709AD6D387" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5X7</accession>
    <name>A0AAD8Y5X7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HTH psq-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5X7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="TrpR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="668" mass="73429" checksum="37BFB43CF4E99720" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6I4</accession>
    <name>A0AAD8Y6I4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA(Ile)-lysidine synthetase</fullName>
            <ecNumber evidence="1">6.3.4.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_008741</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(34) in tRNA(Ile2) + L-lysine + ATP = lysidine(34) in tRNA(Ile2) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:43744"/>
            <dbReference type="Rhea" id="RHEA-COMP:10625"/>
            <dbReference type="Rhea" id="RHEA-COMP:10670"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:83665"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.19"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.19" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032267">
        <property type="term" value="F:tRNA(Ile)-lysidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01992">
        <property type="entry name" value="TilS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.580">
        <property type="entry name" value="Acetamidase/Formamidase-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.320">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01161">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010323">
        <property type="entry name" value="DUF924"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004304">
        <property type="entry name" value="FmdA_AmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054833">
        <property type="entry name" value="FormamaseFmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012094">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012795">
        <property type="entry name" value="tRNA_Ile_lys_synt_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF045496">
        <property type="entry name" value="FormamaseFmdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02432">
        <property type="entry name" value="lysidine_TilS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31891">
        <property type="entry name" value="FORMAMIDASE C869.04-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31891:SF1">
        <property type="entry name" value="FORMAMIDASE C869.04-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06041">
        <property type="entry name" value="DUF924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03069">
        <property type="entry name" value="FmdA_AmdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141130">
        <property type="entry name" value="Acetamidase/Formamidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal" evidence="7">
        <location>
            <begin position="475"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1740646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1395" mass="155340" checksum="63DA6A2A5F1A0D0B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y703</accession>
    <name>A0AAD8Y703_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_009308</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y703"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052420">
        <property type="entry name" value="Espin/Espin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153">
        <property type="entry name" value="ESPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153:SF8">
        <property type="entry name" value="FORKED, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="210"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1740358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="479" mass="53575" checksum="3807B45F39D77A85" modified="2024-05-29" version="1">MSDTPLATTQLFKAINACKWQTVGQQIQSDPSLAKIESDGLLPLHAVCNAPLRAPLKLIKMLLTAHPAAAQLKCGKEDRLPIHILLATTATPYIPYTPPSEDVVSALIELYPGAARVPDVSNQLPIHLACNITGVSEKVLTFILSTYPEGAYVRDFHGKYPLDYATTNKDIPTRKLALAALDRGTLYASISKMTSLRLSKENESKTRSMEEVYEKKLNKMESHAKEERAKLVAQLDSMTKQLKEEKESNQALCEEKEKMVIEKDQAVARAIQFERARYAKLEEQLRSDLADVQLKNMDLLEQLESTQGDLDASKETEEKYIGEIDALKQQLSETNNKLDGTKDEFYMTQEELETVQVELVAATNVIKQKSARITHLEQSLDSTKSSVLHLIQEHERAQANMEKQKEYLGIFINQQINAEKEAKTSLLKMSLLVDAIDVSQRVEGNLEKVVAEEGAMIDASTMTVKEALEEKTELAEESQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y772</accession>
    <name>A0AAD8Y772_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009234</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y772"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="176" mass="19203" checksum="DA2BE6B9152282D7" modified="2024-05-29" version="1" fragment="single">QQVTGLLVNSNGLLLQGTNLRNKVQTTLTLLLLKLQGDVTDGSLGNTLHKMGGETSNLVTHTLGGGDGDLIDDTLVGVEVESKTGVVLLDDGTCGFLDGLGTDSLLFCSDTKAMMVRIHVGNKDLRQKSKSSLWTCVESWFPMAVEVVERCEREHIMCTSDVKKKDNFICLRRKLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7K0</accession>
    <name>A0AAD8Y7K0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007727</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7K0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="91" mass="10226" checksum="642C0EDD6F92F689" modified="2024-05-29" version="1">MEHRAMMSRSQSLRRIPAEAESSSNRTSDLRGSLSFMSSSGWFNKGKVDNTTSMKNEEFGFGLGYEPKKANANHPHVLLRRLSSSNCECKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8I3</accession>
    <name>A0AAD8Y8I3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA pseudouridine synthase</fullName>
            <ecNumber evidence="4">5.4.99.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_008420</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>uridine(38/39/40) in tRNA = pseudouridine(38/39/40) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:22376"/>
            <dbReference type="Rhea" id="RHEA-COMP:10085"/>
            <dbReference type="Rhea" id="RHEA-COMP:10087"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.12" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8I3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160147">
        <property type="term" value="F:tRNA pseudouridine(38-40) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00171">
        <property type="entry name" value="TruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142:SF0">
        <property type="entry name" value="TRNA PSEUDOURIDINE SYNTHASE-LIKE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pseudouridine synthase I TruA alpha/beta" evidence="5">
        <location>
            <begin position="200"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1741168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="333" mass="37923" checksum="31A45E96F399226F" modified="2024-05-29" version="1">MPHQRDRNARASASSTIEDGTQRFAIRFSFDGTTYQGFQSQPYQNTIQDQLEHRLRGLLKRHVRIIAWGRTDTGVHAQGAVATVDLTKDEVERFAKMAGKDYLDETNSNETKAARFLFSVLKEFACNTGFTGNPQVRYGSISSKTVVAVPLDFDARYSALWKRYVYYICSGSFYDQSPFVWSRYAWRVREELDLTAMKEAANLLSGEQHNFSWMSVTQAGELRDPRRIVKLTVEEVPVQLENDDTLPYFLRAQNTNIYKISGSCDFFLYKMMRRIVGILVAIGQGKGDVATLTKCVDAFDKDEKCKEKIPHAFLETAPAKGLCLEHIEYSIPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y905</accession>
    <name>A0AAD8Y905_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">WD40 repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_007722</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y905"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052414">
        <property type="entry name" value="U3_snoRNA-assoc_WDR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44267">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44267:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="347"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="401"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="404"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1741244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="590" mass="63070" checksum="EC73E9F6C6A58FD7" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9I5</accession>
    <name>A0AAD8Y9I5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EGF-like domain-containing protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006713</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9I5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="170"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="630" mass="71229" checksum="A4EB2A54F87E4A63" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9L0</accession>
    <name>A0AAD8Y9L0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9L0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="906" mass="101775" checksum="3E77FCC644F6C698" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAA7</accession>
    <name>A0AAD8YAA7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Leucine aminopeptidase</fullName>
            <ecNumber evidence="9">3.4.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_007858</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>Release of N-terminal proline from a peptide.</text>
            <dbReference type="EC" id="3.4.11.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low.</text>
            <dbReference type="EC" id="3.4.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.1" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAA7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00433">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="entry name" value="Leucine Aminopeptidase, subunit E, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00181">
        <property type="entry name" value="Cytosol_peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023042">
        <property type="entry name" value="Peptidase_M17_leu_NH2_pept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008283">
        <property type="entry name" value="Peptidase_M17_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002076">
        <property type="entry name" value="PRK00913.2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963:SF23">
        <property type="entry name" value="CYTOSOL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="LEUCINE AMINOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02789">
        <property type="entry name" value="Peptidase_M17_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="Macro domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00631">
        <property type="entry name" value="CYTOSOL_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041929713" evidence="7">
        <location>
            <begin position="25"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="domain" description="Cytosol aminopeptidase" evidence="8">
        <location>
            <begin position="467"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1741380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="615" mass="64602" checksum="E6A333E8C7C94AE2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAK7</accession>
    <name>A0AAD8YAK7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007657</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAK7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051861">
        <property type="entry name" value="NET_actin-binding_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32258:SF28">
        <property type="entry name" value="PROTEIN NETWORKED 3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32258">
        <property type="entry name" value="PROTEIN NETWORKED 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="236"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="394"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="535"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="676"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="875"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="990"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1089"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="634"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="912"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="49"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="253"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="425"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="554"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="708"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="737"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="884"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="990"/>
            <end position="1005"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1110" mass="122131" checksum="77B048B5C026B575" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAM2</accession>
    <name>A0AAD8YAM2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAM2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="96" mass="11050" checksum="5BB97759DC956D8B" modified="2024-05-29" version="1">MDSSLPPPPLRSRVPAAEDSESRAHATLTVDTEALTEARVVKKKKKRWAIMIHDDWFTTDLYIHSLIIHQTCLEPDRSFHGCVHINSINDKYIVFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAM9</accession>
    <name>A0AAD8YAM9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Zf-MYND and TPR domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_006828</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAM9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="16"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="81"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1742263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="304" mass="34030" checksum="BE873FDFE9A33749" modified="2024-05-29" version="1">MSTESNEAVDTMLLCCAACGIVEVDDIKLRECADCDLVRYCSDECQIEHKSQHEAACKKRTAELRDEILFKQPDSSHLGDCPICMIPLQLHLKRSAIMSCCSKVICCGCSHGTIRGEKASLDFPCPFCRKSTRIIDEDVMKQRLKRVGANDPVAMYQEGTFQFEDGNYERSFEHFIKAAELGHAEAHNLLSRMYNNGHGVEKDNGKAIHHVEEATIGGHPTARYNLGVYEWNNDHNERAVKHWIIAANQGEDDSIKALMEAFKSGVVSKNDLAAALRAHQAAVDATKSPQREAAEDFFRQIDKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YB75</accession>
    <name>A0AAD8YB75_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YB75"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="457" mass="51006" checksum="071BBCE6BFC6240D" modified="2024-05-29" version="1">MMNIDVSSTSTQSSNEMDGRNASIRPPSPHAGDKRRPGRKESQHASTEAIRKHAVTALATSISRPEHLTALTVGLRAFNHSDESVHDEEIDSVADAALCRLLSFLLFKEFSIDKLDSEERLNCLPEEILRNCQLFELIYGCSKEKITASFQRVGPDLLRLLCHIIMYEIERYALNPELSHPPDSKSRGGLDSGAQQDTCLQSATRILFLYARVQSLTEAMAQHKKLLSLCITLIKYPIDVVPFEAQHNVLFILANMACCRSCVLTLSSYDSLMDTVAYAADQNRVTTATEKTSWAEYYQPLRFNCTAFRCLLNLSHPKENKITMVGKDGLLRSIAYVIGLQTSQWVGIPQTLNDMATQTRRFAMSTLRNIASAPPEQKYRLCSFKNGILLDALCTAAQDDHDPVAKEKSFAVIFNLVCSNTVEILTMHPQLLELLVDAVASSHPRHPMYHKGASTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBQ3</accession>
    <name>A0AAD8YBQ3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ankyrin repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_006695</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBQ3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052420">
        <property type="entry name" value="Espin/Espin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011646">
        <property type="entry name" value="KAP_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153">
        <property type="entry name" value="ESPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153:SF8">
        <property type="entry name" value="FORKED, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07693">
        <property type="entry name" value="KAP_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="207"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="KAP NTPase" evidence="5">
        <location>
            <begin position="323"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="695"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="755"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="710"/>
            <end position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1742130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="834" mass="92006" checksum="C4934341D61AFFA5" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBX0</accession>
    <name>A0AAD8YBX0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBX0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="508" mass="55912" checksum="9013B1EA20801B72" modified="2024-05-29" version="1">MAMESSATAGNLLTPPKAPLGAAYLDRAVTITVLSCDGVVTKRYEPKLARKKNRQVTKTTTSLVASFSQTLSANSSFLTHVPSMPMEHLDESCTKPDKAKSIPQPTVKWPSMDVGEVGGETLGQELSTLRFTRRFDEKNISETFPISLSLSRCGKMISLGRADVIISVKEKRHSYVNVPISSTIKKVGVSSPMKNKSSSKNRIPMVRVKGDNLQFGLKDCSVLSVLVSVTDVQEQDDTNDVQENELMHNQDFEEVTNDDDECEVNDVTFELDDKYENILDFLNEAGDDAIDLSSENDDIANCDEEEKVDCPRPEGVIDGGDIDDDEQNKIRDAPALPQDEDEESKINDAPAVPQDEDEEKVVDALNLQLDEGEVDEGNVDEDEETVTDVPALPQNEADECEEDEETCYFWPWVYAILKIKSSRPGALTLLLDGGEVDAGDVNEDKEKVADAPALPHDSVGEQKVTVENTDEEQEEISIVESVEEDTNNNGTASGMLLRLFGYMQTSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBY4</accession>
    <name>A0AAD8YBY4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006059</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBY4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="200" mass="22197" checksum="022887523C9C0E55" modified="2024-05-29" version="1">MSDLTAIVAESVESYARTCANAKEENERLQAEIEATRLAALSVARYSGTINITGQGGLPVYACGYFQEAVFNGSGFEPSDSEGNPVYKFGINLRNLVECPINDVENAEIRVNGVKIALVGDGQNASDTDLISGQYWELRSYGSLRTDWNDIFLDFIVDPIPGRDINWSFHDWSTCNPEDFDNFTFSSINIDTNKYYQGNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YC54</accession>
    <name>A0AAD8YC54_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Subtilisin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005336</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YC54"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042070970" description="Subtilisin" evidence="1">
        <location>
            <begin position="18"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="125" mass="13859" checksum="10FC74D5FA854E81" modified="2024-05-29" version="1">MMLLLLLSTLLCLCASAYQATTIPPLIDVPTFSLSTSSGGDDASSSSSTMNILTYASPVAIKPHRMWSISLYKGTLSHENFIKEKRGILQLLRPAMLSDELDYISTRTLREMDIISEFGRIKDIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCL1</accession>
    <name>A0AAD8YCL1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006428</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCL1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051826">
        <property type="entry name" value="E3_ubiquitin-ligase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765:SF411">
        <property type="entry name" value="OS02G0248440 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765">
        <property type="entry name" value="RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="2">
        <location>
            <begin position="308"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="389" mass="43338" checksum="96F9796EF8AD0137" modified="2024-05-29" version="1">MIIMSPIDAAAAAFGYIQHGQKNSTQPSHVTNNDENICFNKEKSEQDDDSCATAILLKRFASFLGSVIHDFGLGDTFVQPISDIRVTARIISEMVTSFTASSSKLPVPDATEDISLDSSIYTLSEHQTPVATAPHSGGGLALLGSELFLEEDDNERLDYSISQLDVLRMSRAASRRLRVDSIDQLPTTIYHEEQDEATIHHEEQDEATVDHEEQNELICSSHEDFEEDLPAHVHMPVVDVTKEAVLKHTLQQGDHPEFSWLIVPEDPLQDDLTRISQHNDQLRAVPETISICSSRHSEEKVRDAFDHCVICQEPLQEGDNVRVLPCQHLFHYGCIDDKLTIGENSEEDAGCPMCKKDLEEQQGESYHSDGSVPSWSFKRLGSLLASMGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCQ8</accession>
    <name>A0AAD8YCQ8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">WD40 repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005344</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCQ8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080008">
        <property type="term" value="C:Cul4-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990756">
        <property type="term" value="F:ubiquitin-like ligase-substrate adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052596">
        <property type="entry name" value="AMBRA1_autophagy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22874">
        <property type="entry name" value="ACTIVATING MOLECULE IN BECN1-REGULATED AUTOPHAGY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22874:SF1">
        <property type="entry name" value="ACTIVATING MOLECULE IN BECN1-REGULATED AUTOPHAGY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="181" mass="20738" checksum="CAD0AFC192B18A9C" modified="2024-05-29" version="1" fragment="single">QRTHTRLNHGDHTVKITCAHTGKLLRQLEGHPRTPWTVKYHPTNYRIVASGCLGCQVRVWDWNFQTERYGRNGGRVWNVNGGDDISLVVVVLVVVVVVVVVGMIGKLLGIWVEVGLLVVQGVLLISIGREVLVGLRMNEWIVQMLLRLIRRLRQQQQYLALVHGKYNTDNTPRRLQHLKME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YE69</accession>
    <name>A0AAD8YE69_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005427</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YE69"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37231">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37231:SF2">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1743830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="167" mass="17986" checksum="46F5A8F93D9E060F" modified="2024-05-29" version="1">MKTMAKATGMFAAYAAIVVTSAALLLSPSNAFAFSPVTKSIMHPNKMTSTSSRCRFPLHQSLSHNDKSTCSSFLPKKTTSCRRKLHESPTLLGISGLIASTIVLYSESVLFNTGCGLPAGPFGLVGAVEGISYLGVVGLIGFSLYTKVKQEVDFRLDLVAYWELQRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEI1</accession>
    <name>A0AAD8YEI1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEI1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="134" mass="15074" checksum="BBFC3023D977AFDF" modified="2024-05-29" version="1">MDRTSLKSPYAVLRSNERKQRETRQPDEPLDAKLQIENDASDEDVEENDTAPSIESAKMPDNAREENKKDSDSSSTKQSSIEHAEKSNDATHPRKTQNEDKSKDPLYWLAGGESDSDEESWDFDGPMILPPPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFT1</accession>
    <name>A0AAD8YFT1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">26S proteasome subunit S5B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004389</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFT1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019538">
        <property type="entry name" value="PSMD5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13554:SF10">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13554">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10508">
        <property type="entry name" value="Proteasom_PSMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0647">Proteasome</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1745098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="421" mass="46475" checksum="1EB39929B7E8E105" modified="2024-05-29" version="1">MVPPSDVEEALSAFAAALNESSASSPDASILESKLSGPDGVVTALLPKLWLPQSDPNNSLSILVHLVEAYPKKYMNVAASAIRRDIEHNFDTTKMDTTAGRSNSDTQTGIATDAHAALLALCKWDNHEYHKSNTCQTLFQHLATLWKYLQQQQKDKLRESSTAQMRIAALMIDVCLLGGKEVALALSDDTGSIAANDSLDALEVLAVENKDYSMTRNDELHNGLLYLIGSSSENVEFDPINGYAALRLLTEICRVGISSSTECTTKNKFYSLLESLQGTGRSIRPSDYISLSLYHAFGEANNQKDPTECLLASAKSPFVEERLGAYNVLRAMASRGCCVRMLLLYKGEDGNSIFVEWLLNQDNEFTNEGRQAKYNIVQSLLADDNNIEGLISTKAFREMQLWMKRGPAHITTFRGIWQLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFX1</accession>
    <name>A0AAD8YFX1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003778</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFX1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24121">
        <property type="entry name" value="NO MECHANORECEPTOR POTENTIAL C, ISOFORM D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24121:SF23">
        <property type="entry name" value="NO MECHANORECEPTOR POTENTIAL C, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="437"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="511"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1157" mass="124875" checksum="8589F1809F3D8E04" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHS9</accession>
    <name>A0AAD8YHS9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sulfite exporter TauE/SafE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_003713</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHS9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052017">
        <property type="entry name" value="TSUP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30269:SF37">
        <property type="entry name" value="MEMBRANE TRANSPORTER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30269">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN YFCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1745789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="309" mass="33590" checksum="AF5115B2E78905F3" modified="2024-05-29" version="1">MEEYVQHGTSSQLPTLVVISLFLGMGKGGVPGLATIATAATVVTAPTHIPNGLGYAVALMVPILTMIDIYAAYLHQHALDWNTIGMILGQYVAERYLTDKGARLFIGLLLLFILALRTWKQMDKEEDREDETVAVHMPLIDRKNEGNVRLDAMESGESNKSDDDPSTTAGLRNITTTRRKASIDPTKRLVWACFVGLMGGMATMLTNSMGPILNVYLLSIAELTPQSYVGTRAMFFCFLNVGKLPIRVMGGSLGLPMMPLAFGLGAVSVLGVFLAKPIMLSINERLFVKLELSVVAFAGLRLCYMGIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHT0</accession>
    <name>A0AAD8YHT0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Leucine-rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHT0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1745340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="170" mass="19156" checksum="BCE7D33981D6CCCF" modified="2024-05-29" version="1">MGIRWLYSATKVKFGKELESIGNGAFCRCKSLERITIPLKDNMITENGIFQGCKKLESVDLVEGAVLRRIINALVLDEWRNDMDVEINAINQSLPTTPAGDDFYDVGGKAEAVQLWIRSVLHKIVQYKAQHHSYVNEAATTLQLDLPNDIVNKNVLPFLELPSYTFEGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHT6</accession>
    <name>A0AAD8YHT6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003644</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHT6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="74"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="243" mass="26982" checksum="3715BC5C2AF6A482" modified="2024-05-29" version="1">MMDISTTEAASSPPVTPPKKQPKILKQGSKSATPPRLYDEATFTTLDVDADRMPLSILLEPPAAPFTREGTEQEQQHQELPPNTTPSRPSSRVTSTASRAATRSSPITQLFSIQDYNKHVLNSSPNQLCIIRFHAPWCQVCRTTNVSWERMASKIVKMNSSNRNVKFLSVSLDGKNEDVAELKDMLNIEGVPQGVIHHASDGVFGQKVNLNRKNLGVLKKQLESYLTNDMGADMFLYGLKKET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHU9</accession>
    <name>A0AAD8YHU9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SNF2/RAD54 helicase family protein</fullName>
            <ecNumber evidence="7">3.6.4.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_002170</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHU9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015616">
        <property type="term" value="F:DNA translocase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045003">
        <property type="term" value="P:double-strand break repair via synthesis-dependent strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000332">
        <property type="entry name" value="DNA repair and recombination protein RAD54-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.850">
        <property type="entry name" value="SWI2/SNF2 ATPases, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050496">
        <property type="entry name" value="SNF2_RAD54_helicase_repair"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629:SF7">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629">
        <property type="entry name" value="SNF2/RAD54 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="219"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="156"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1746826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="431" mass="48348" checksum="86EE6CAC55AAAA41" modified="2024-05-29" version="1">MALNSIPVKRRVLLTGTPMQNDLEEFYAMVDFTNPGILGTQEDFRRKMLYPILRGREPDATDKQKQKMTEIQQNMSSIVNDFILRRINTLNAEHLPPKLVQVVCCNLTEIQQNMYQHLCNSKAMQHVLDGKQVNCLGSIQMLMKLCNHPSLVVNDDSSSSLGQSGRGGRNKKKISYAEEEEKSSAAPGADGIAKFMPYEAMSGGRNAPVYPELSGKMFVLWRLMREMRKPGNGGDKIVIISNYTQTLDLIGRMCKENNWKSCRLDGSISMKKRQAMCDEFNDPSSSLVAFLLSSKAGGCGLNLIGGNRLVLFDPDWNPAVDKQAAARCWRDGQKKRCFTYRFLATGTVEEKIFQRQLSKEGLQSVVDDKDQVNALSTKDLKNLFKFRQGTPSDTHDKLKCERCQIIVDDAEAEAAKVLPKKLAACRELLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIF7</accession>
    <name>A0AAD8YIF7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chloroplast protein import component Tic20-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003279</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIF7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041938007" evidence="2">
        <location>
            <begin position="20"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="133" mass="15503" checksum="6C33494CA18E16F5" modified="2024-05-29" version="1">MRLPTEVVALAIFFAKSCTLCFGFTSHSHINSMTKVAKKADMIRWSKEDNTNDEDSKGNEQQQQPINNLDIFGQPKDKERRKFEDEGDIRGPDRIKSCVPYMLPLIDGDSFGRFIYERIPRLHLWTTYFCDHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIN3</accession>
    <name>A0AAD8YIN3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIN3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="292" mass="32879" checksum="ADA859C6EFF65377" modified="2024-05-29" version="1">MSPLSRLDDSPSPPLRFHHPHDVSSRRAADDDMMERKSSHRKRNSSPDSIGTVIVPLPLPPSPPQQRGSYHTRRNNIPLPPIFSLLRRSQRSLSFAHGSSYAGPRPVGKDGNPLKSCLSKTKQGRVDPKVSFSHVSIREYSRVVGDNPCVCCGPPLSLGWKFNKRGRTDIDTFEAIKTQSSLANGRQCLRLSANERERLLLDIGGSSHSQIMKGSMQANYDNKLRWQSFDKLGGENHYKSIGPRERVLIMKESARRKFDRACKGTSSLKEQQDLWDMAQEVTLTKLKRHTTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIS2</accession>
    <name>A0AAD8YIS2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Amine oxidase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_003875</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the flavin monoamine oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIS2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20404">
        <property type="entry name" value="Tudor_Agenet_AtEML-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050281">
        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742">
        <property type="entry name" value="FLAVIN MONOAMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742:SF386">
        <property type="entry name" value="LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="4">
        <location>
            <begin position="545"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="199"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="490"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="13"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="42"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="77"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="199"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="509"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="523"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1745951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1052" mass="116716" checksum="F0DA2030F9A21065" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIW6</accession>
    <name>A0AAD8YIW6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_002226</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfotransferase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIW6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11783">
        <property type="entry name" value="SULFOTRANSFERASE SULT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sulfotransferase" evidence="3">
        <location>
            <begin position="45"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1746882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="133" mass="15479" checksum="3EFB4EF2C5FE73DF" modified="2024-05-29" version="1">MESTKKEGNISDVNRWPNWGTKPYKVMPHISPESKRIGETFRLRPTDVVVLSFPKTGTTWTQNCCEQLRTRAGGYDFDDITIRQPWIEFAHDLGQDLDNDQIAPPRIFKSHQLYRLSIQEANTCVLFVIQKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIX2</accession>
    <name>A0AAD8YIX2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003819</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="480"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="609"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="710"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="852"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1131"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1309"/>
            <end position="1368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1428"/>
            <end position="1513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1537"/>
            <end position="1574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="296"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="364"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="541"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="628"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="684"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="721"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="761"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="793"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="893"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="926"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="947"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="960"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1131"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1161"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1227"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1318"/>
            <end position="1332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1345"/>
            <end position="1355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1457"/>
            <end position="1468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1483"/>
            <end position="1513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1546"/>
            <end position="1555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1574" mass="171928" checksum="4819D57E81A19C64" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJA1</accession>
    <name>A0AAD8YJA1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cystathionine beta-synthase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002924</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJA1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041987492" evidence="1">
        <location>
            <begin position="22"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="506" mass="56296" checksum="6C03199D20F2CFC4" modified="2024-05-29" version="1">MMRCFVFILLLPALTFQSCIAWVCPSLEPFATTLISRKNLPSSVLAISQTPYISDIGQSWDGVHAKERHPANVAAPDSDADAAATDSSTYLIHKGRAIKMIKRCVAIEGLSVSDGWTPQASEAFSLAVEAVVRANPILTGQLIEEKTSLWPWAQPRTLRVIPGVFSPESHSFLTTINPPADLASPAQVLYEEEINKGTSAKELFQHVHSHVAPRLLGKAEFSYDQIKNASPLFEAKLMDFGDGYAAYSIKMSHALGDGTTFFQVIKQISSYMNGHEPQPINWDNPLKATHEIYPETFSNQDYERSYGGPFGWGVFKNIRTLGKRKCEYLLLSKDKITQKKRELQKSDENARISSNDVVMSVICEMCGSSDIFAFDRSVRGIKDDVDKSDAGNFFWEIPFEREKAAANPSVIRNILMSESGTYYDTDEVPLMPFLNGRVGRITSLASITQKTTFPGSKVICQFPSASFISDLPLDVAVIFRFDEEHFGIMHNFRRVNPSPLLSEIIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMF9</accession>
    <name>A0AAD8YMF9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMF9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1749301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="572" mass="65023" checksum="EA4BE0A6E08B8F93" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMN0</accession>
    <name>A0AAD8YMN0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">H(+)-exporting diphosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000742</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMN0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042106100" description="H(+)-exporting diphosphatase" evidence="1">
        <location>
            <begin position="33"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="345" mass="36292" checksum="9ED0FA2FF27CF3DD" modified="2024-05-29" version="1">MMMLRRDRRALCCMSAALIISTCVLRSESVVAFAPPSTSAAKRRIQNSMLLESTANNGEMVLARDGDRLLNVAFSNLDDRDKYETVLTGLCAKVIDGGAANSKNGLVDPIRLMEESNSNGITIGPRGIISLVDATALASDARIMAKILSLAITNGSILRYGTLQGEINPFPQSSASAFPFGNRNNNDIERLQNLPAVPVDDRAAEVSQAVLFSGIVGGCVAINAFGGLFGMEDLTPITNLVVGIAITTVVVDNFFDAIVMGGSAVAKMNEDKLPAGAKNMSAPQKEDMPMGIGTGSMTGSVVRGLSRLLNVNTERDCQCEAAAVFAAYSLGSLLCIQPNALEGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMV1</accession>
    <name>A0AAD8YMV1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MBL-fold metallo-hydrolase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001999</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1748036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMV1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16279">
        <property type="entry name" value="metallo-hydrolase-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42663:SF6">
        <property type="entry name" value="HYDROLASE C777.06C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42663">
        <property type="entry name" value="HYDROLASE C777.06C-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="2">
        <location>
            <begin position="148"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="399" mass="44322" checksum="4F803115ECB0DCD4" modified="2024-05-29" version="1">MPNKPTALAKTTPAIPSQHFYWLRLAGIVAIAALAVASCSLLYNYYHDKKSGHRPSSLSASCESTSQEVKPGLLFLGTGSSTGCPKPNCALLFNAGKNSVPPLHNNSNEYMEKMKNLVEGNPSVMIVHRNNDAIDGQEASSDASNETRTVLIDAGKTFTENALRWMPRHGLTSIDSVVLSHEHMDAMAGLDDLRGFQMQPTRNAKTGLPEQTLKTQLFYLFPKEESTQSLVAGEKTCPDGSKIHRHVSKLDWRVVQNFKPFNAAGLEMIPLPVMHGEDLVCNGYAFSVADGEQRMNVVYLSDISRMLPETEEFILEKLPPIDVLVVDSLNWDRSNKTHFSFKDALTLIRRLKPKRTFLVGMSCDQFLPHDEANEELKHLDVKVELAYDGLFLPADAHDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMZ6</accession>
    <name>A0AAD8YMZ6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000368</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMZ6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042212827" evidence="2">
        <location>
            <begin position="17"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="87" mass="9601" checksum="259C523244DF1396" modified="2024-05-29" version="1">MFKQLIAILLIALSERQWNFNEGRGPWGMKKNAEIWNGRELITGKGVIPSIQDGDFVGFAFVGFAGVSTLALTAWLAIKGDENSIKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YNB8</accession>
    <name>A0AAD8YNB8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YNB8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="295" mass="32543" checksum="E7CCFAC6C3346F24" modified="2024-05-29" version="1">MSLNYHELTMNEPRDSPAKRKQHIVICTIMGVMFLHSGIMAGLFHPMSIEKGEFPGGEFTHKFLTRDYAASSGTQRAIEADLGIENTDKMGWDAPSDSADLLFSVFLDNDGSIPGGMTRYASGMITEDKEKKRMLLDTNSKAEEMTAKDYPKNVKYDVAILPKVNAATVLHPTTGGVWSALLQQYKIFPALKKYYEELGGSGSFVMISTCSEKQGMCMYYVPLSEKEAFYIGNELTEEYAVQYAGASFMEKFLGLDFNDSPLPSFGIGGTKVSNVFKGIKKLLGISSKTSGKEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YP41</accession>
    <name>A0AAD8YP41_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2854 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YP41"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021275">
        <property type="entry name" value="DUF2854"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35551">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35551:SF1">
        <property type="entry name" value="ACCLIMATION OF PHOTOSYNTHESIS TO ENVIRONMENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11016">
        <property type="entry name" value="DUF2854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="227" mass="24597" checksum="E5711DC707E0765B" modified="2024-05-29" version="1">MSDEDDWAAPKSAMIGGAGVNNAGEPPFEIRGFSLGNLVIGAGIGITVLSFADYLSTAGGDGLSMSGVGFVYGIPIFLAGSALKYAEIEPVPCISTPAVSESLFESKATEIIKKIKQDVTRHRYGDEAHLDTTVKKLGLVIPGKDYPQLKELQEDVTEDGDLAFTMVWQSLDTPYKMWADEKRRKRYETFFGPGVGAEVVKINAEQRMVGIRLTTGGLCQKSIWLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YP61</accession>
    <name>A0AAD8YP61_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pyridoxal reductase</fullName>
            <ecNumber evidence="5">1.1.1.65</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_000776</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.65" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YP61"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050236">
        <property type="term" value="F:pyridoxine 4-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050791">
        <property type="entry name" value="Aldo-Keto_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625">
        <property type="entry name" value="AFLATOXIN B1 ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625:SF5">
        <property type="entry name" value="PYRIDOXAL REDUCTASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042048578" evidence="3">
        <location>
            <begin position="22"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="199"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="125"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1748837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="514" mass="56335" checksum="89B4FFC752AF6BC2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3I4</accession>
    <name>A0AAD9D3I4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Flavodoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_016722</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the flavodoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000063">
        <property type="protein sequence ID" value="KAK1732581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3I4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050619">
        <property type="entry name" value="Flavodoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010086">
        <property type="entry name" value="Flavodoxin_lc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01752">
        <property type="entry name" value="flav_long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006738">
        <property type="entry name" value="PRK09267.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42809:SF1">
        <property type="entry name" value="FLAVODOXIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42809">
        <property type="entry name" value="FLAVODOXIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0288">FMN</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="7">
        <location>
            <begin position="55"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1732581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="222" mass="24336" checksum="ACC60B33E5F9E40D" modified="2024-05-29" version="1">MSRCKWPNNCSSCSHKFDIMKFIIAIVAVSSFSGTTLAFAPSASSRIATALNAKVGIYYSTQTGNCEIVAEYIAQAAGLEFADIGDVSDDMILGLDSIIVGAPTWNTDEEEERSGTEWDTWLYSSLPKLDLSGKKVAVFGVGDQQSYNDYYCDAAGELYDQFKKCGCTMCGFTSIEGYEHSASKAERDGKFVGLMCDEDNQYDLSEGRAKDWVDQLKGEGFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D465</accession>
    <name>A0AAD9D465_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GCK domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016909</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000068">
        <property type="protein sequence ID" value="KAK1732374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D465"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="305" mass="33503" checksum="0C365E825A44B534" modified="2024-05-29" version="1">MSSAIIAAAARHARNLPASLGCRALGSSASTAASQVVGASVTSSGAYNAHNTRNNLTSLLTLAAATSLAAAYSILSIDNNIAYCEATTGPADVMEESDDFVIVEDGMDAGVADSDTSSPDSPTDAGPADAEEDDEEDPSNDEETSCSICLINRQGPCRKYWLKFERCMKEHSAEKEKTIAEADSKEAEEAAKKEEEDDDTELTEQEQIEREWDAFMEKSIRPGEDDDDDDDDDDDEDDDDEDQDDDENESGKEGIPEKEEITLAERCDKFMIPWIGCIQEHRNIYSLISNDFYQKTTLILWKTLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4U8</accession>
    <name>A0AAD9D4U8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Fatty acid desaturase</fullName>
            <ecNumber evidence="14">1.14.19.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_016306</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the fatty acid desaturase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.-" evidence="14"/>
    <dbReference type="EMBL" id="JATAAI010000055">
        <property type="protein sequence ID" value="KAK1732975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4U8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016717">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03506">
        <property type="entry name" value="Delta6-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353:SF88">
        <property type="entry name" value="DELTA(5) FATTY ACID DESATURASE FAT-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353">
        <property type="entry name" value="FATTY ACID DESATURASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="400"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="431"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="13">
        <location>
            <begin position="134"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="70"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="78"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="96"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1732975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="586" mass="66625" checksum="9FA21C878A2DCF15" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5G4</accession>
    <name>A0AAD9D5G4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heat shock factor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_015549</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000045">
        <property type="protein sequence ID" value="KAK1733694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5G4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000479">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF206">
        <property type="entry name" value="HSF-TYPE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="5">
        <location>
            <begin position="2"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="102"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="224"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="294"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="343"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="309"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="343"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="353"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1733694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="402" mass="44932" checksum="7D4EB975019ECAE7" modified="2024-05-29" version="1">MPHGRAWKVKNKELLVEEVIPKFFGQSKFASFARQLSGWGFKSAIRLCTDFGCYYHECFLRGHPRLTALMRRVSPGQGKVTPNMHSEPDFYLIAQQCSLETPADVPDRDDKRVVSKVAKASVSGRQKSQCPGDSDVGDEASGYKEDDDPLMTRKTAEPGMDGMSNQHQWDPFDQEIDSTHLHHQEAAPRAAMNQFFSMRSQSHSFASGGTKESESNAQAAMNYDPFPYQQQSGSGSYRDRGYSDPSPMSNHQLGPHSAYSMHPAPARQEYYGSNVNQYAAGSSHQAAAAAGYYYPPHHHHSQSQQQQFHQHDAHSHHDMSQSHDYWYRNPNYNNYHSAQGLAQAQAQGYAQAPTSANTTTQPHSPAQGDRNRNSPHPLPTFSPLKSFQEDEGESDSKPKPQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5U6</accession>
    <name>A0AAD9D5U6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA exonuclease 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_014272</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the REXO4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5U6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06144">
        <property type="entry name" value="REX4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000007">
        <property type="entry name" value="Interferon-stimulated exonuclease gene 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037431">
        <property type="entry name" value="REX4_DEDDh_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047021">
        <property type="entry name" value="REXO1/3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801:SF45">
        <property type="entry name" value="RNA EXONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801">
        <property type="entry name" value="RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exonuclease" evidence="11">
        <location>
            <begin position="177"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1735206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="360" mass="40510" checksum="75E6B622268D8FA4" modified="2024-05-29" version="1" fragment="single">MVFYTKKAKAEMRRRRKKMAKSHGDGDDGAADNDDNITEAGHKRRADQMINDAAQISTTSTKKVKTTGNNDQPTTITIPANLTTLEAKKFRKDARRKARGAQGHSEDKLKFIIEGQEAIEAEKEAAAKEDKKKSKQKKEFPRINDILSTHATQKKLQEKIDKQTAINSAIPLAEKQKYVAIDCEMVGIGTDGVKSALARASVTNWDGEVLLDTFVRVPERVTDFRTHVSGVRSKDIHAKNEDAMDHEECRLKVGELLMGKILVGHALKNDLSALMISHPRSEIRDTARYKPFMRATGRSGGKLRPRKLRDLVYENVGMRIQVEGEAHCSIDDARASMELFKYARSRWEKELEKGNKGIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6D1</accession>
    <name>A0AAD9D6D1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peripheral subunit-binding (PSBD) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_013482</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6D1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="entry name" value="E3-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042281396" description="Peripheral subunit-binding (PSBD) domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="3">
        <location>
            <begin position="374"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1735776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="434" mass="45833" checksum="016FDE1E997B756A" modified="2024-05-29" version="1">MKLPTIIGVSTILLIGVRGFAPVSQSCSSTSSIATIRTNAASSSYSKLAVTADNDALLDALTQTVDAATRAASASSQIAQSLSSTTTSSAPLMTSEAITTAQSNLDILHQNLLTSTDPSTLSNALHEALQTSITAADHALATTSVLSYNLAHFDSILATSMHNAHPFASIMTPEMAEISQAKLALLLHNLSGVDANDHFLTNFMSHVDSRLDGLDSVGDSNMVLFGAAAVVMAYSQREVGVANYKEELRRKIELGEFDADELVKEVSLSGAEANEASVTATDVSFSKDPAIVTTVDASPLFQHNREKEDKPELIMAAATVTEPEAAPKPPTEDIPMESLLKQVEEVAVNTMASVVETVTKKKTVEAKKIKNEPTSSPLARLLAMELNLNLVDIGKGTGKNGKILIADVRKFHSKLEEARSSIATSGAYFASVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8K8</accession>
    <name>A0AAD9D8K8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 61 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011366</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8K8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1980">
        <property type="entry name" value="Nitrogenase molybdenum iron protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38360:SF1">
        <property type="entry name" value="F12P19.7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38360">
        <property type="entry name" value="OS03G0120000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53807">
        <property type="entry name" value="Helical backbone' metal receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041927553" evidence="1">
        <location>
            <begin position="17"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="488" mass="54687" checksum="4D560BC8C604AC5E" modified="2024-05-29" version="1">MKFFLAAALLVATTSGAYVAPTTNYDRCLTPSEADDIATAISNGIDVDLFPDKVFPDQSSYWDMEYHGTYKILKNTQDTISTSYLLYQCGLSTMPFDETELAQFDSVFPVPYEGGIVVTATTQIPNVEILGRRDQICAFAITENLVSSPCLSQVLIPEGKEDGSVTILPLYNDTAVEDYLAANPDSLILGGSWDSAPKMKNKVVISDIGESPQKAIDDGVDVNEAQAEWLEPVGSLFNQEKFAHTYNLERKQRYECHTDNAAQLAAVADDARPKVLWGYFSDYSSGFDAPASPNYYVTYAEHCQADLLIPEEGKEGSIDSWGYKYMTDEEWLEFGRDADVWIYPSDNFNKLLSQKNEYLQQFKAVQNEQVYDYQMSGGEGWFEKRLAEYDIVLLDMCQVVGRNLETFPPHQRMWLRNVFTESPRTLGVCTDVDELFEPRHMECVRNDEAVNTDSDAPGILSEQPSSANQVGLAHAFLASMVLMWTVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8N6</accession>
    <name>A0AAD9D8N6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010831</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8N6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="211" mass="23897" checksum="0FE07880C1F77260" modified="2024-05-29" version="1">MSNSQQLPAVAADNRRNKSIPRMAIFLVFLPSLLFNIATMHSSLSKSTRSPSDDEAAYLDYPVLEHQQSRRKHQASNNPHHNPSTTTELLPTAATHPRGSTPYNCGVVFFFHVPSTGGASIANWFRKYARPPNGNITFYQKWTRSIGRDGKFRPNQHQVHDAFIEGMNAHVENLAADEWRSGQYHLVQPPLNSTEDLWYKWRATVEVKGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9S6</accession>
    <name>A0AAD9D9S6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)H-dependent oxidoreductase</fullName>
            <ecNumber evidence="2">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9S6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.360:FF:000078">
        <property type="entry name" value="Chromate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050712">
        <property type="entry name" value="NAD(P)H-dep_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30543">
        <property type="entry name" value="CHROMATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30543:SF21">
        <property type="entry name" value="NAD(P)H-DEPENDENT FMN REDUCTASE LOT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADPH-dependent FMN reductase-like" evidence="1">
        <location>
            <begin position="8"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="224" mass="24253" checksum="B7356C71CA57FF56" modified="2024-05-29" version="1">MTTITLKTIIFLGSARNITPPWGGDSRLGDRVIKWVKSVMESRKESLGADTIAHDFRIIDPIEVFGPNGALSYSGGELSKPTFFMDQSTLPAAAKELQEAIKEADCYLVVSPEYNHSIPPALSSVMGHFGGSNYKCKPSGIITYSPGVFGGIRAAMAIQVMLHELGCLPVSKLCGVGNVSEVLNEDGKPIDPNNRLLKQLPELLTQLEWMAVAMANQRKLSGTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DA36</accession>
    <name>A0AAD9DA36_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DA36"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="999"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1006"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1056"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1068" mass="120573" checksum="FBA79E61AE7ABC7E" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DA51</accession>
    <name>A0AAD9DA51_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-galactosidase</fullName>
            <ecNumber evidence="3">3.2.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lactase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_010954</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009341">
        <property type="term" value="C:beta-galactosidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005990">
        <property type="term" value="P:lactose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000018">
        <property type="entry name" value="Beta-galactosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004199">
        <property type="entry name" value="B-gal_small/dom_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050347">
        <property type="entry name" value="Bact_Beta-galactosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006101">
        <property type="entry name" value="Glyco_hydro_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006103">
        <property type="entry name" value="Glyco_hydro_2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023230">
        <property type="entry name" value="Glyco_hydro_2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006104">
        <property type="entry name" value="Glyco_hydro_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46323">
        <property type="entry name" value="BETA-GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46323:SF2">
        <property type="entry name" value="BETA-GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02929">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02836">
        <property type="entry name" value="Glyco_hydro_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02837">
        <property type="entry name" value="Glyco_hydro_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00132">
        <property type="entry name" value="GLHYDRLASE2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01038">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="beta-Galactosidase/glucuronidase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00719">
        <property type="entry name" value="GLYCOSYL_HYDROL_F2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042277779" description="beta-galactosidase" evidence="7">
        <location>
            <begin position="22"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="domain" description="Beta galactosidase small chain/" evidence="8">
        <location>
            <begin position="966"/>
            <end position="1285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1738285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1291" mass="145409" checksum="99BE2C00A1CED1BE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DC33</accession>
    <name>A0AAD9DC33_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CPW-WPC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DC33"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042190391" description="CPW-WPC domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="146" mass="16310" checksum="019A109CC203806E" modified="2024-05-29" version="1">MMQKLFLLFLAAIATGAEASWGEKSNEDWYKDCPQSETNKYSEECYKATCPPPFVCDKMTPDEWVEKALESYPRCCGDDLTECKCPVKDVWPPFKAKIGDYCAKVEICEPSATDNSVPSSTSGDVSFLRGGVDDVNEQIQRKELSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DC56</accession>
    <name>A0AAD9DC56_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF3291 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DC56"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021708">
        <property type="entry name" value="DUF3291"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11695">
        <property type="entry name" value="DUF3291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3291" evidence="1">
        <location>
            <begin position="42"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="140" mass="15885" checksum="168D4A52FB30D051" modified="2024-05-29" version="1">MTTDMNLVSITGFVTKDLLSTIKFLYYTSRAFKSAQIAEGNISSTTFKDADIFMTLTVWEDKESMRKFYLGGEHREAMRQTKPLGLYAKVHSYLTDEVPTTEEAIKIWRNDGRIVHGEPDPKYGDEIVSDEDVSTECIGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCY6</accession>
    <name>A0AAD9DCY6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_007897</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCY6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051068">
        <property type="entry name" value="MFS_Domain-Containing_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23510">
        <property type="entry name" value="INNER MEMBRANE TRANSPORT PROTEIN YAJR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23510:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="332"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="370"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1741419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="549" mass="60244" checksum="668235016BA3AE00" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDE0</accession>
    <name>A0AAD9DDE0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007248</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDE0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053259">
        <property type="entry name" value="Golvesin-related_Golgi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32301">
        <property type="entry name" value="COUNTIN RECEPTOR CNR3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32301:SF6">
        <property type="entry name" value="GOLVESIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041937560" evidence="2">
        <location>
            <begin position="21"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="848"/>
            <end position="873"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="913" mass="103484" checksum="B18A6AA8EA83FF36" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DE10</accession>
    <name>A0AAD9DE10_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">PAS domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_006216</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DE10"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005216">
        <property type="term" value="F:monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098703">
        <property type="term" value="P:calcium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.20:FF:000060">
        <property type="entry name" value="Sensor protein FixL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024862">
        <property type="entry name" value="TRPV"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10582:SF2">
        <property type="entry name" value="INACTIVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10582">
        <property type="entry name" value="TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="610"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="648"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="689"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="733"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="789"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="903"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="12">
        <location>
            <begin position="130"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="13">
        <location>
            <begin position="207"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1059"/>
            <end position="1089"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1742619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1089" mass="122601" checksum="9D28CF7B82799D6C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DE70</accession>
    <name>A0AAD9DE70_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006441</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DE70"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050602">
        <property type="entry name" value="Malonyl-ACP_OMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13090">
        <property type="entry name" value="ARGININE-HYDROXYLASE NDUFAF5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13090:SF1">
        <property type="entry name" value="ARGININE-HYDROXYLASE NDUFAF5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="3">
        <location>
            <begin position="180"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1742844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="428" mass="47024" checksum="0C7007B64C556B5E" modified="2024-05-29" version="1">MSANKILSKHRLVGSLLRRHISSTKTSSSCIIYKRIIATGQQSHHAHYFSTATGGSETAPFDRSVKLKQRTRAAESCRQHYHYNNTNDVSSSRPILPYDYFHREIAQRLVDRLDDINIRENGEGGFPLALEIGSGAGFVHDAIMDGCAADHNEEEEEDELLLDSSTDNNNVIYSGRGGVRKLVQLDSCSAMLHRDDDSTTASSTTDDTTTICETYKLVTEEEGPFPFPDGTFDLVISSMAFHWINDLPRLLTEIKRVLKPDGCLLFALPGGNTLPELRSSLVLAELERTGGVSTHLGPYVDLSNVGSLLTGTGFKLPTIDVDDVQIGYPNMMVLMEHLGRMGEGNACLNRKERVGLGTFVGAACLYNELYSATEHDGDDDDEEDDGIVASAQIIYGIAWKEHEAQPKPLERGTATHKMTDIAVTKTKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DED6</accession>
    <name>A0AAD9DED6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006292</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DED6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="144"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="326"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="353" mass="38916" checksum="F4DF59F703134A5A" modified="2024-05-29" version="1">MNTKRRRQRTDQQGSTASCSSSSTTTTSSSLKSPLKNLKRLFKPSPSSEEKIDAARRKASERLKPKPFSQSKVDRLRELKEIKAESTLSSNSIRNDGLQEKEKPPDDGMTRHGIIFSCSLMIYGMIQIILLLPKIIQSSGYQTFIVDVCLIILQASCLRSLLCMLALLAFDAIELGRADTLIKGRRLYISQVSKYTFLISVAIVLSSLIVVAAAMFLQKAACFIIQGESDLIIHVHVARISDVMEKLVDGSEDATMGALLKYLMRIVTILLKSAWTVVTRLSTSLAPAIVSLFSQPPSEWKNSVAVCEISSPSLLPSQLVHRTLSLFSYITTRLGVFCVAAFGIAQVLLPKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEZ0</accession>
    <name>A0AAD9DEZ0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3'(2'),5'-bisphosphate nucleotidase</fullName>
            <ecNumber evidence="2">3.1.3.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_005916</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.7" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEZ0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008441">
        <property type="term" value="F:3'(2'),5'-bisphosphate nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050725">
        <property type="entry name" value="CysQ/Inositol_MonoPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43028">
        <property type="entry name" value="3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43028:SF5">
        <property type="entry name" value="3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600760-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1743295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="473" mass="51300" checksum="EA014CE53451E009" modified="2024-05-29" version="1">MDLSATSAQNVASSTASKTTDEIHNTLQLDADVGRIVSESFDSVGDMTDMTINDISITELLSTCIDACRRGCEVIRNVRHKLVQSSNVVGSDSKFFCCGAVKYKISNDPRSALTEADEASQKVITECLHNCWAKEIRSGLIKVVGEEDEGDDDFVDSVPLYDMMAHFDKYNTPSIDQEPVQRDLLSPSDSTQILHSSNEKNELIIFIDPMDGTREFVENRIENVQCLIGITLNGKPIAGAVGMPMIHEDKIEIAYGIDLPADSAQSTSTPLSKLSGVKYFNTLNPLVKQLSVTDTGMGDYIDGEDDVKKLVVLSGDSKKPALTMSMKCLESDVLGTFVDSAPPIRKIVAGGCGNKMLFVQRRFEALSERIRHQEGTDLSSIIGSISLAPPGSSSWDTAGPTALLLAADPNAVVTDLIGRPLVYDGEHLSNDCGVVVSAGHMATRIHREMCEKLRRDEVFCEALGVVLCDAEII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGG7</accession>
    <name>A0AAD9DGG7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGG7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="101" mass="11071" checksum="2B6692556E0501DE" modified="2024-05-29" version="1">MVNVEIEGAAEIEGAAWSLGRVQGSVRILFQGAANSIHDVFIRLLRDLRARDEKNQGRGLCRCCGVVQTHEIVGFPVAEGYHSKIGWYTMGLASDALQWGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGG9</accession>
    <name>A0AAD9DGG9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGG9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="96" mass="10159" checksum="E224846045152AC4" modified="2024-05-29" version="1">MMTTKNVGPPFEELHLSNLPSEEHNIESSESINTVVNCINLYDNTVLTSLNLRGCGISHAGATKISCALASNASITVLDLSNNRSATQESALLIGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHB3</accession>
    <name>A0AAD9DHB3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Armadillo repeat-containing protein 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_003784</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the beta-catenin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHB3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043495">
        <property type="term" value="F:protein-membrane adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071562">
        <property type="term" value="P:nucleus-vacuole junction assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045156">
        <property type="entry name" value="Vac8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47249">
        <property type="entry name" value="VACUOLAR PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47249:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1745860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="509" mass="56215" checksum="8B12940EB16090DC" modified="2024-05-29" version="1">MSTSISQEKVISPSQMKLKQRSRYSQMRKIPPSPKDNRKKASNAASSDRSPRKDEVRSPRASTRRTSSSSPRSSPAIHTTTSPRIEPAVQKIEPVVQKPKDADELQTELQQQMLASLKEPDASLKALLDVLTDPSATHHRRVNACGAIKTLTLKKTNQIPLVRTAGVVSSLTTVLCTVAATEEERTRCINALMQLCIPEENWKIVYLFPHTAEALARNMADKYPQIRYAACLSTSFLAKKNRKEMASNRILMYAIARVIEVDKNGNLEKKSAKDKKVLIAARLCTLKMLLHLSKDKDVSPKLARMESITTALVTVANHMEKDANILCMATLTNLTRHPDNLNHLMFKVPKLASIFVTNVEGSEVECGKCALYALQNLSCDSNCRQELANTANLLGSVTKAAFKHDCPEQQLSALHTLKNLSDDPFNLVTMTNTPGCTATLLALANNSGSGMAQYLACDTLATLSHWLLTLSARKNTKLMGDEKDGAESGAKRVEMGRRTFETSTYQMWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHB9</accession>
    <name>A0AAD9DHB9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Pheophorbide a oxygenase</fullName>
            <ecNumber evidence="11">1.14.15.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_002706</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.15.17" evidence="11"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHB9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032441">
        <property type="term" value="F:pheophorbide a oxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050584">
        <property type="entry name" value="Cholesterol_7-desaturase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21266:SF32">
        <property type="entry name" value="CHOLESTEROL 7-DESATURASE NVD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21266">
        <property type="entry name" value="IRON-SULFUR DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Rieske" evidence="10">
        <location>
            <begin position="71"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1746099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="602" mass="66762" checksum="FABA41DF3EDFEFAA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHV4</accession>
    <name>A0AAD9DHV4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peroxisome biogenesis factor 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_002795</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHV4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008733">
        <property type="entry name" value="PEX11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652:SF25">
        <property type="entry name" value="MICROBODY (PEROXISOME) PROLIFERATION PROTEIN PEROXIN 11C (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05648">
        <property type="entry name" value="PEX11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="1" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1746188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="299" mass="33533" checksum="1D835013E03A01B0" modified="2024-05-29" version="1">MPPLRQRKPGNTADEDDSSEHQEDGGVSNGQQAQNKPLSNPPPTPAPSPLLDTVCTFGAQTFTTDQGLKIIQWSSWAIAYLTASSRQHKETLSPALQKLSGEVSFTRYVLRFYGFFQSLEGYRSGSWAGGSWDNPKIAKIAKYLMAGSMLFYYPLEHVAYAGWQLPTLSKFSRDNANKMSALSCIFWTTYIIGDFWASCLKWNELKKKLNDLGRLLAIKKRDDDKAGMMEVEKEQHAVAKRIRIVKLQVVRCLLFILPSVNWSLPNWATNPLLGELPLNGLMLAEAYTSVYQTLVGMRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHX7</accession>
    <name>A0AAD9DHX7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type E3 ubiquitin transferase BRCA1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHX7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="703" mass="76996" checksum="6EC5957C16C0C42B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHZ9</accession>
    <name>A0AAD9DHZ9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">riboflavin kinase</fullName>
            <ecNumber evidence="2">2.7.1.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_000450</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.26" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHZ9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008531">
        <property type="term" value="F:riboflavin kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009398">
        <property type="term" value="P:FMN biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.30">
        <property type="entry name" value="Riboflavin kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023468">
        <property type="entry name" value="Riboflavin_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015865">
        <property type="entry name" value="Riboflavin_kinase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023465">
        <property type="entry name" value="Riboflavin_kinase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749:SF6">
        <property type="entry name" value="RIBOFLAVIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749">
        <property type="entry name" value="RIBOFLAVIN KINASE/FMN ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01687">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00904">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82114">
        <property type="entry name" value="Riboflavin kinase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="Riboflavin kinase" evidence="10">
        <location>
            <begin position="217"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="113"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="116"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1748511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="417" mass="46414" checksum="043D80985F6A7ADD" modified="2024-05-29" version="1">MYLLPQKLKHMVIFKSRAIIQSASAQSVAHLSTQRIRVILTNLNTMQLPPLLMLPALLLLCCCSSSLAFSILSRSATAVTFRRTNHYAINDSSDGESQQRGMEEAFASLDALSPSDWDDEENQNSNDEDYESELKSSRTDETGASDTGKSTREEVEHYLEMTTELDGTAVQDIEEDWEEEVEDIINDQIESGQDMDVEDKENSDVNEDLPWESINPILRLRGQVATGYGRGGKKLGVPTANLPASLFQSALEDVATGVYFGWSVIEGENEKQGRNGPIKAVVNVGYSPTFEGKENKEKIVEAHLITKSSPMAVIDEASISENVLDKGDESDIIDEIEDDFYGETMRLQLIGFLRPEQKFDSFPDLIAQIHRDIGTADLALKAMPFIFSKEDAFIQDDAEWIGSDGGDDVASWEFETW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJ31</accession>
    <name>A0AAD9DJ31_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_001336</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJ31"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021259">
        <property type="entry name" value="DUF2817"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10994">
        <property type="entry name" value="DUF2817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="235" mass="26196" checksum="3B0D24D3ECF60125" modified="2024-05-29" version="1">MIYQNNHHMNYSYIYERGGVNGIRDCVNCEDHCIKGVQQCQKDNSFSAIPQESWVFYGGNGRWENSVVAVQHAIDEFAGFSLSSGDADAQSKVLWIDVHTGLGKYGSYTSLIKKEVTDNNLWTSQLNTLVADLEEKQASNSKAVSSGYEQTVGFINGDVLCPPPACFAVSQEFGTRPGVAVILSLVLENKFFNWGKSEYAYLTSNAFQPRRLSWRRIALRGGSEMLLAALKFQPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DKF1</accession>
    <name>A0AAD9DKF1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YkgJ family cysteine cluster protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000979</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DKF1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005358">
        <property type="entry name" value="Puta_zinc/iron-chelating_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35866">
        <property type="entry name" value="PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35866:SF1">
        <property type="entry name" value="YKGJ FAMILY CYSTEINE CLUSTER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03692">
        <property type="entry name" value="CxxCxxCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042029107" evidence="2">
        <location>
            <begin position="17"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1749040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="210" mass="23631" checksum="D104D2256E56F54F" modified="2024-05-29" version="1">MLLFLIILTPQADALANKPFIRKLRGVIPANYPLSLPWYEDGLNFSCTGCGKCCKVDGDVWLAPEEVPPITQHLGLNLSEFRSNYIKAEITPSDGNEEESWMCLKRDEGACVFLGKDNRCSIYDHRPVQCRTYPFWPSLLSEEAAWLEEAVLPDEVTIDEGSSERHWSPELGGCEGIAVTTTNEIKEGEASDSDDEQESTLFKEKRLKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DKJ2</accession>
    <name>A0AAD9DKJ2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pentatricopeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_000707</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DKJ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="18"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="53"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="157"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="352"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="370"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="385"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="405"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="428"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="446"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="480"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="499"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="510"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1748768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="543" mass="62041" checksum="C21B29AB405CB2BA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2KDL7</accession>
    <name>A0A7S2KDL7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Hexosyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006505</name>
        <name evidence="1" type="ORF">SMAR0320_LOCUS1485</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="HBGZ01002106">
        <property type="protein sequence ID" value="CAD9573799.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S2KDL7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CAD9573799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="389" mass="44543" checksum="A2EB01629846D4EA" modified="2021-06-02" version="1">MAPPRRHLHNKKHRHHIIFASIIILLLILVAAQLKQELFVINHSHQKAVEIEANKVDDPNQNPVQVAFGLSGNHPGFLSEFEVALKSVLLSAPLERNLSVHILADQEAFVSLKGIFNRTELSTWQTRNPTEIHAYDVTPDHPQMKHEIEDVHKPHFPNYVLDVRHTMGAFYRLFVDRYVSKKAAKHILYMDTDVVVMANLEALWKLVEHQERNVLFHWGKTMCSGFVVMNLQRMKEILTLAKRSNFTEADGSKLDLNSDQTIYQAVNISYPNEVNVLPPGWDMTVTNIWQSNNHPYDKNFPNVGMLHFNGGGSTQEAYFGDENGTEHNFITNFKDTWGNGKFYATLPWEWARYQAMSLVRPGSKGHSIQFYFSKGMQGAVNVSESERLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRU5</accession>
    <name>A0AAD8XRU5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_016852</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000066">
        <property type="protein sequence ID" value="KAK1732458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15560">
        <property type="entry name" value="PHD2_3_BPTF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013637">
        <property type="entry name" value="Lys_sp_deMease-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037869">
        <property type="entry name" value="Spp1/CFP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46174">
        <property type="entry name" value="CXXC-TYPE ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46174:SF1">
        <property type="entry name" value="CXXC-TYPE ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08429">
        <property type="entry name" value="PLU-1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="8">
        <location>
            <begin position="1439"/>
            <end position="1491"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="8">
        <location>
            <begin position="1791"/>
            <end position="1841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="100"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="294"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="630"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1137"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2137"/>
            <end position="2168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="126"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="144"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="179"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="338"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1137"/>
            <end position="1152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1732458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2168" mass="237316" checksum="D4D8D6CD5E58FF0C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSK5</accession>
    <name>A0AAD8XSK5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_016212</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000054">
        <property type="protein sequence ID" value="KAK1733074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSK5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="30"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="30"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="51"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="70"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1733074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="95" mass="10641" checksum="BAF80980CC69A0B4" modified="2024-05-29" version="1">MGWTEMPKRCEACKSNRVKRLADQRSKLDSKKRNMCFAFQKGECPHGANCKFSHNPKHAGGIKLRNNASGREEESVSKESDNENDGAPVEMTEAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSP2</accession>
    <name>A0AAD8XSP2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ethylbenzene dehydrogenase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_016653</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000061">
        <property type="protein sequence ID" value="KAK1732676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSP2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36044">
        <property type="entry name" value="HEME BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36044:SF1">
        <property type="entry name" value="HEME BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042257273" evidence="3">
        <location>
            <begin position="29"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="300"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1732676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="328" mass="34940" checksum="82545B0A5A327AD1" modified="2024-05-29" version="1">MIFPKTKSAAFSLALSIAAFETLPTITAEDSCTSIDYITCIKTASPPTLDASFISDWGGVEVFESPLTGALTSKMYTAGNMKIQCVYDATDIYFLYQIPGKYMFDINDNKKFPEACAPYAVDIGAHWELKTTERGVMYGPNEGTGNDLIANKDDEFAVGPYCRVDDNFGTSPGNEWSGAWDFTGNATNANGAEGYYIFETSRSLTTPSPETDAQLTPGTEVNFGVSFWDPFETASGWTDAGHVVTGCSEDWIGLRLVDENGAATPVFDHVGGDEESAEPMESGTDGMETTSTSTPAPSGAASIIAGTAFTFVAAVFATCVVFEAISIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUF2</accession>
    <name>A0AAD8XUF2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015758</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000047">
        <property type="protein sequence ID" value="KAK1733585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUF2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="736" mass="83438" checksum="A3F92BF3DE97C3E1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV05</accession>
    <name>A0AAD8XV05_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HPP family transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015186</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV05"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007065">
        <property type="entry name" value="HPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058581">
        <property type="entry name" value="TM_HPP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33741">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN DDB_G0269096-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33741:SF5">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN DDB_G0269096-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04982">
        <property type="entry name" value="TM_HPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="300"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="HPP transmembrane region" evidence="2">
        <location>
            <begin position="207"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="381" mass="42195" checksum="C03CE22325151772" modified="2024-05-29" version="1">MELSTLSLLDSVLPHSKPQRVVWREVVPITEDPDQPFNLRLKLAAQAGIGLAAGVRFHFRGTQGLVVYMARGTTDINKLKSETNEQYLLSATDVIGSIVCLRNPRRDCLAERRQAREATRRRLRNKMLAVIRIGGPILREMLKREYDEGIVPVLYEDTPSSNISSSMDSRRSAYSLASFQKKTLSIKNRIIMAARKWKGANNDPPPPFSNVEALWTFSGCFLTILMLLYFSDFINEQNSQYSLVLGPFGALVTLQYSLTSAPASQPRNVILGQAISISIALCMTYTRLEANIRRSLGTALCVSLMARLGVTHPPAGAAALIFTGGGYTWVHMGIMLAGNVLAIISAAGINNFNVKRQYPTSWGFGYWIKYVCPRKGSKKGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVL5</accession>
    <name>A0AAD8XVL5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_015012</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000040">
        <property type="protein sequence ID" value="KAK1734245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVL5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="225"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1734245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="276" mass="31396" checksum="F8BB0D0F1A43E58B" modified="2024-05-29" version="1">MGRKRNQGKARKAAKAKAREAAEEERGNNNQKADGQQQSLADQMQQLEMIGNMSRHDTTIKCRHGFEETETLADFSSEFILAFREAFYGVANEAEAALSACLIAAAKATKDKFAEVWNDSTNMEIAISFILRAGTIAILEDEHKSAKDCALFARFLEQYAAVQFKQTQVLINWSKIIRRGDEHSLVKFFRRRIPCCCLDEKYQVVKSITKMGICYNPKCHFPDGCVERSKLLYCSRCRIVTYCSRECQKACWTKHKLQCDKDAGLKAKFDAEQQNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW92</accession>
    <name>A0AAD8XW92_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutaredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014478</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XW92"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015038">
        <property type="term" value="F:glutathione disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03419">
        <property type="entry name" value="GRX_GRXh_1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014025">
        <property type="entry name" value="Glutaredoxin_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694">
        <property type="entry name" value="GLUTAREDOXIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694:SF18">
        <property type="entry name" value="GLUTAREDOXIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00160">
        <property type="entry name" value="GLUTAREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="1">
        <location>
            <begin position="74"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="196" mass="21459" checksum="A124BFD2A13445C6" modified="2024-05-29" version="1">MKFPVIVGAVLVAGSGVAVAFTSRNSAAVRSASTAFANNFSSRASTRSTTAAYATPMEFAKAEIASNDVVVFSKAYSTLESMNIEAKVIELDQRDDGNDIQAAVLDISGQRTVPNVFIKGKHLGGNDDTQAAARSGKLQRCWRAKYLDVHIMCTLVSILVKTSRHTALFEQYNKISRTQNKINCSYSQMYLQDKRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW97</accession>
    <name>A0AAD8XW97_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Metacaspase</fullName>
            <ecNumber evidence="4">3.4.22.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_014637</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.22.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XW97"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12660">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050452">
        <property type="entry name" value="Metacaspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104:SF30">
        <property type="entry name" value="METACASPASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104">
        <property type="entry name" value="METACASPASE-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="Caspase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C14 caspase" evidence="3">
        <location>
            <begin position="142"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C14 caspase" evidence="3">
        <location>
            <begin position="282"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="58"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="110"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1734764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="501" mass="54770" checksum="9FC8BA1DB4E3E2A9" modified="2024-05-29" version="1">MSEKRRPSSSRGKPPPPPPPRRQSSSAGQSKKAELTIKSSSSTRREARSVKSHANSKSRRDSQSRSKSRPRDDSRNSKPRDKSRSRSKSRPRSSPRNNENDTQQRRSKSKSSSSRSKPPQSKGTRSKSSPRSGTPHGKSSSSSSSSNKGNKAQAESFNAKKRQQKFASQAKKAIPTNIRMISGSHDMQTSADVGNINAQFELPNPAGRAGGACTAALLQVLYDAHDRGDVDMSWVDALREMREILHEKGFDQIPQLSSSRMIDVCDPFVITPESFDPGFNKQRAVLIGINYKGQKGQLSGCHNDVHNVTQYLKEVQGFKDENITILMDDGMHKPPTKSAIISAFKRLVKQTKEGDVVFCQYSGHGGRLPDDNGDEDDGYDETLIPLDFQKSGHIRDDDLLKILIHPMPAKVTMTCLMDSCHSGTVLDLPYRFVGDGDHVEMEMNDRVNFTEALWSGLSVAAGVVAGNAIADAVNVAPEMMILGGGPNAIHEHSDTACCAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWF9</accession>
    <name>A0AAD8XWF9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1800 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014314</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWF9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014917">
        <property type="entry name" value="DUF1800"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43737">
        <property type="entry name" value="BLL7424 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43737:SF1">
        <property type="entry name" value="DUF1501 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08811">
        <property type="entry name" value="DUF1800"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="936"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="936" mass="103180" checksum="913BD0870550428D" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWZ5</accession>
    <name>A0AAD8XWZ5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWZ5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1735456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="112" mass="13169" checksum="6F6D575DF1C0F606" modified="2024-05-29" version="1">MMACCSKVICDGCFHANYMREFEERLENRCHSAEKITKTYEECDKQKMKEWRRMIQCYKGNIAVHLVLMKAAELGDAAAHYRLSCMYHNGMASRRWGKGNEVEKDCEKEFTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXG0</accession>
    <name>A0AAD8XXG0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_013949</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXG0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1735335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="31" mass="3568" checksum="60DDA6B03822107A" modified="2024-05-29" version="1">MYALMVGHFTPPDQSQFSPPSYNVIPTDLQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0D1</accession>
    <name>A0AAD8Y0D1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pre-rRNA-processing protein Ipi1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012757</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0D1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="488"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="254"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="496"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1162" mass="127563" checksum="F1589A53828ECD40" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0H9</accession>
    <name>A0AAD8Y0H9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_012718</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0H9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042148025" description="Transmembrane protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="319"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1736696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="440" mass="46916" checksum="FA4412CA44D52C30" modified="2024-05-29" version="1">MHSRRAFPLLLLAAFSVTAANAFIPRRQRRYLTEASRPSIGSSSQSLHKRDATLPFGLQLRGGDADGDVASEVENGEETIDDKAADSDQAANKVWEEEIKRTQSFYQEQSASDASESVDDGANNDEDINSEVSADQSDTTVDVIEGDDIEPAQANEDIVDAVEGEFDAEVNDTVEVDAVDDVSDEALQEATEEEVVAENEVQDEVSEEEEVAETLQVEVVTEEQTSDSGEVGNVDAEEVVSSEEAEIKDTVEESDEVAKEEAAGGEDVEGVVAAEEDVLDGDTVGEEQSTADEEKAGSDGVVDSSVTPLGDASDDGVAEVDAAAAATAESSESTPEQDASSIAVTDEPTSLVRKVSAVVQVMLLRGRIAVSKNKGVQYLAQNKPKIKVIALASLGGVLSLLVGGHVFLAMQETDVLELPNDEWREEESYVDEADEDDNDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0T0</accession>
    <name>A0AAD8Y0T0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L36</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_012737</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0T0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1760:FF:000001">
        <property type="entry name" value="60S ribosomal protein L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1760">
        <property type="entry name" value="60S ribosomal protein L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000509">
        <property type="entry name" value="Ribosomal_eL36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038097">
        <property type="entry name" value="Ribosomal_eL36_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10114">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01158">
        <property type="entry name" value="Ribosomal_L36e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01190">
        <property type="entry name" value="RIBOSOMAL_L36E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1736715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="107" mass="11771" checksum="3295D4909C5119B0" modified="2024-05-29" version="1">MARNGIAKGANSGFVTEKRERAARPSRSTGKLGKRTALCREIAREVAGLSPYERRILDMIKTGGSAADKRIYKFAKRRLGSHKRAVAKREDIKAVNSKMRAKQAGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y159</accession>
    <name>A0AAD8Y159_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011844</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y159"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="311" mass="35000" checksum="EB081A585F888CEC" modified="2024-05-29" version="1">MSPSSIDNELEEVADMFDSIGDHRVIVAAATLDEMDRKPSDEVDIADVSVSVADTEHADNTHPYLMRYADIYAHSQEFSDPDEVSKAGNTKFIKISRSTDQGDFKKGEVVIYHDKETNTSYEATIVDVHYDERKQPHYDLMFKGDNNDNSDGKEDTVRLSVKDGIKQQPKTLEAVSETTCSLTETNAVKCVNFEINPTPLFVAMYNGEWEAAQKRLRTHPEEASVWVARYNTNADDIKVFRWRLLPLHLCVALSGSNDDDDDATDHEEAAAPDVPDDEKMSWIKRERATIPSTHTFGCPSQGLSSSHTMYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1U5</accession>
    <name>A0AAD8Y1U5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heat shock factor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_011768</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1U5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF206">
        <property type="entry name" value="HSF-TYPE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="6">
        <location>
            <begin position="149"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="55"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1737482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="386" mass="42399" checksum="D52247A04EC4B6E2" modified="2024-05-29" version="1">MLHRNAASGGMDAAQQANLLNLLQRQQLQMGNLSVANHANNSVGAAMAMMATLQQQQQGGASGGGGGTASHRNSMTGVPGATTVGSSFNMGGATDMNTFMMNMNYMGGVGGTHPPTATVALNSSNHSNNNNEKQGPLLLIPPKKSKNKHKQTFSMKLMNILSLRECHSSIRWMPNGRSFCIVDSKILVEKVLPVYFKEAKYTSFTRKLNRWGFKHYSLPINSAGGGSSATAEKEMSIYSHDKFRRDDPELCETMDGGHRRRNARKDEERTRQFYSQLKPEVRDLLRQGQGVGVSAGEEGASVVGVINNFHYKLKPLQSRQEQEEHHPLVKTLLDSRLSCSKCKRCNCNCCNNNSRCTATATTTGESNDGHVILHVEQCCFNVCRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y321</accession>
    <name>A0AAD8Y321_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Leucine-rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y321"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="282" mass="31635" checksum="FD296F0BC48426C2" modified="2024-05-29" version="1">MVDLAAGSDVDIFVYLGGEQEVPHDIKHVIIDESVKIIPPRAFWNRTKLISVKFHNGIEKIEGGAFNRCWSLRRATLLGVREIGKCAFSSCVGLSKMEFGDKLETIGQGAFDFCAALRRIVIPLKDDMFPLFGRHQRYTQFEYCVNLTAVDVAITGIHKTVSSFLLENWRDEIKEEIGCINQILPKTPHSDKTAQISQWIRSVLGRIEHYKAEHNRLLQEATALLELALWKAKLDEKGDGDTKGDVTTEGAIVVEKSGRSDRRITSGASIVIKNVLPFIQLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y372</accession>
    <name>A0AAD8Y372_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010856</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y372"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="307" mass="34964" checksum="CD2B0086FDE3E8E1" modified="2024-05-29" version="1">MTSTSPKKVVLHADDNFIKHLYAEHDKDHKPCPTCSFTGGPNKNTTQRKKTSEIINRRVNKFYHLFDPMMNFLLMNRYAMYNKQHKIDVETMPVDHVMVVHLIDLPSDNSGSSRPQLRIDKLEARAVTDLNDAERTSLQHDVSSKEPDEFLLPHLVSYRTPNEGYIWTSIRTNSYDFNPLIIGRVSQKALMGRIIAFAQGINEIAKGERQDLYDMIKKQMKEARKTKVAVPLRSLLQERNVAVAAGNAHAASCHQLNESDKENIDHSQNNTIPADRNDDGDCTGLNKLNTTTQKRILKDEKKATKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y385</accession>
    <name>A0AAD8Y385_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA pseudouridine synthase, RluA family</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010889</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y385"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluA-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050188">
        <property type="entry name" value="RluA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600">
        <property type="entry name" value="MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600:SF87">
        <property type="entry name" value="RNA PSEUDOURIDYLATE SYNTHASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="2">
        <location>
            <begin position="2"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="170" mass="18984" checksum="80A7F959F0F8CA3B" modified="2024-05-29" version="1">MIVHRLDRDTSGVLLLARNDDALKQLHNDFKNKARVKKTYVALVCGHWTGQSSRSCVARDEGEIDLPLVRDIERPPFMRVATAETEERLPVTRLELHPITGRTHQLRVHCAAMGHPIVGDSIYGFCGEGAPHGGLSNAKEECMLCLHAQQLNVFHPYTNAPMSFSSRSPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3A4</accession>
    <name>A0AAD8Y3A4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_010180</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3A4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="5">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="107"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="139"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1738864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="173" mass="18048" checksum="96D352B1D0CF9D47" modified="2024-05-29" version="1">MVDTSSYKVGIVLSLEDKSKSGGKPLKVCSVNIGGDPICVVTNAHNVRQSSRLVVAPIGSTIINDEGEEMEIKKTAVGGVMSEGMFCDSRMLGWGSGSSGIAAQVPDSFEVGSAPPTSKPGSPPTASSESAIPAVEVKPLFEKKLTKEEKKKLAEERKAARKAAKEAKKAAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2024-10-02" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3Q4</accession>
    <name>A0AAD8Y3Q4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010532</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="1">
        <location>
            <begin position="321"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1294" mass="145819" checksum="ECDBC94C1C1BA30C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y400</accession>
    <name>A0AAD8Y400_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tyrosine-protein kinase ephrin type A/B receptor-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010914</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00185">
        <property type="entry name" value="TNFRSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.50.10">
        <property type="entry name" value="Tumor Necrosis Factor Receptor, subunit A, domain 2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011641">
        <property type="entry name" value="Tyr-kin_ephrin_A/B_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46104:SF1">
        <property type="entry name" value="GENE 9195-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46104">
        <property type="entry name" value="GENE 9195-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07699">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01411">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein kinase ephrin type A/B receptor-like" evidence="2">
        <location>
            <begin position="328"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine-protein kinase ephrin type A/B receptor-like" evidence="2">
        <location>
            <begin position="372"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine-protein kinase ephrin type A/B receptor-like" evidence="2">
        <location>
            <begin position="434"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1439"/>
            <end position="1473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1439"/>
            <end position="1448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1457"/>
            <end position="1472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1592" mass="173176" checksum="DE53E39ED3D1BCC8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y491</accession>
    <name>A0AAD8Y491_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">WW domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011049</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y491"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47852">
        <property type="entry name" value="OS06G0298400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47852:SF2">
        <property type="entry name" value="WW DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="146"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="218"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="355"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="419"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="464"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="286"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="454"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="526" mass="58460" checksum="D4BD421C00A074B8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5D6</accession>
    <name>A0AAD8Y5D6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009672</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5D6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47679:SF2">
        <property type="entry name" value="C-TERMINAL OF ROC (COR) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47679">
        <property type="entry name" value="PROTEIN TORNADO 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1739913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="368" mass="41074" checksum="711524D260F2A777" modified="2024-05-29" version="1" fragment="single">MEGLCRNQSIERLDIWRCEIDFSSLTPFIVNNSNLRSLELWNVDISLGNASNLAMALSRRQHESLTRFVLDQNNLDDDSLSEITAALSDYSSLGSLCVMGNQIRREGCLLLGTIFGSSALCLKEVDLCRNELDDEDLQTLAAALTNATTLQRLSLSRIRSITAAGLRALSHLFSSACPVETLFLEEMNIGDEGAEALSDGLMGNTTLKHLVLTPNSAGITSTGWAAFSRLLCDTSSINNTYRSNHTLKHIGGGYHYVPNPDGSDKLFRSGNCFRGIPPAIVQYLKKNKEYHSLQDAAKIKIGWCHTDIPVEVFFEYKLKFLPLLVRWYGRFGTRKCSNCQNEKTREFQRRELSAVYKLIRGMPMLTVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6Q8</accession>
    <name>A0AAD8Y6Q8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">cAMP-dependent protein kinase regulatory chain-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_008632</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the metallo-beta-lactamase superfamily. cNMP phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042781">
        <property type="term" value="F:3'-tRNA processing endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.15.10:FF:000029">
        <property type="entry name" value="Cyclic nucleotide-binding domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46018">
        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46018:SF2">
        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="11">
        <location>
            <begin position="498"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="12"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="305"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="437"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1066"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1127"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1171"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="14"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="331"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1131"/>
            <end position="1149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00061002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1740537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1367" mass="149245" checksum="7F5170CC63DFD992" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y771</accession>
    <name>A0AAD8Y771_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y771"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="294" mass="31398" checksum="5B231C941F76CF05" modified="2024-05-29" version="1">MTLSNNSSFLNKLSTLRDFVTGMGMKVSESDFSFNVELALERILTGDNSASYDNSSGGVVTSSSSFAASSKKSSAMATPSSKKRSAAAIKSSTKATPKSSNHNKRSRPATFVQLVVQSVVTEAANIHRATAIITTDYSYANDGHELLDFTQNWKNNTHSTSSSATPIDPMVRFRSTSGNVEGSLNSYLCSSMSENLLNDPIEFFDLFSNNGGGGGVTDSKLFFSEGKGSGGRRGKGEELPLFEGNKSNDGGDGIPSKKTILSTDRLDDDDSDATVSISNNNDEDGDMKIIPWKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7A6</accession>
    <name>A0AAD8Y7A6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short-chain dehydrogenase</fullName>
            <ecNumber evidence="4">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_008520</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7A6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901:SF1">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="90"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="280"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="459"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="844"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="93"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="280"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="299"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="477"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="850"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="940"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="952"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="968"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="979"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1000"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1051"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1088"/>
            <end position="1097"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1740425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1108" mass="123183" checksum="6224177B2C18CF58" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7R6</accession>
    <name>A0AAD8Y7R6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_007832</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7R6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022036">
        <property type="entry name" value="DUF3605"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35020">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-INDUCED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35020:SF2">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-INDUCED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12239">
        <property type="entry name" value="DUF3605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1741354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="264" mass="29987" checksum="B637D1CD51A87D5D" modified="2024-05-29" version="1">MGCSQSKSTTNAVNWDRIPSVIRCNASDSDSVCSESTPTTEKAVIVPTISNAHRLYIPNDIIFSYGSIDKVIECLHAKEKRVLTKTYNRQGRCCRKATHTEKITFEMPIHCLKHAKKDEQGRFIGNGSIFWRLPEVEASRVVDYEANKKKYTNAYDRLHIESFGWDAVETVDGKITAVRGKNATRKIVWMKNKYPYAWEDGVEHYVCWSTDAPAQSIDECIKNIEENVGADKEAVWFTSSANHLLVSGIDHIHVIVRSKPEYVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7S4</accession>
    <name>A0AAD8Y7S4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl hydrolase (Family 16)</fullName>
            <ecNumber evidence="3">3.2.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008329</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.-.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7S4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08023">
        <property type="entry name" value="GH16_laminarinase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF55">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 16 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="151" mass="17002" checksum="C7CD525D4F71AEA5" modified="2024-05-29" version="1">MYCHGYRPALWMLPESWMYGGWPNSGEIGIMEAVGYEENKFHGSVHTGAYNHGIGTQKTGSISKPEADWHIFEIDWQVDKIRFAVDNQVYFVFAPDDTSDSAKWPFGEDFHLLLNIAVGGNWGGFYGVDAAAFDGDVGQYMEVDWVRAYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y837</accession>
    <name>A0AAD8Y837_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Late embryogenesis abundant protein LEA-2 subgroup domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008844</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y837"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117070">
        <property type="entry name" value="LEA14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041985421" description="Late embryogenesis abundant protein LEA-2 subgroup domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="311"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="494" mass="53472" checksum="83EB3AEEE6A260AE" modified="2024-05-29" version="1">MTRRSIFRLAAAIAVVTTTLSSSFISASAADFELPLFNPKEIIDTDTPNESFIGPNCAAHTNCTECGGALSALCHWCAKNNKCHAKGDPFGCLIGASCDAPPPTPKPTKPPTPPAKKCIDFKDCQSCANSSWECHWCPQDNDGTCHAKGSWSGCASGADCFAIDRCQRLEPERVYHGGTFSKASFEGVGPVATTVLAVIMGLVLCCATCCFAGATFVKGAVDDLVRPDDMVYEDDGMSGQYDDDDNQLELEAPLLLENGSAGETDGEAIADANRRSNSLTRSEQVSVTQLSAMSVTTNRHPPKKKSSIRRMYGVCQVVYLVTIFFTVILFVVGMSYAPRQPQYNVCTNQLGWKSIIEGMASLKVSASFDLLISVYNPNRVEVDLKNGAGQFHYDGEYIGSFEIPEGKIAEEAISDIIVKVTFTPDKWQALSLTSEYYRGTLRFIVGGHAHVSVPALGNYSFEAKFDDIEVNTNDPSLDDTHLCACPGWKKPGHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8N1</accession>
    <name>A0AAD8Y8N1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008307</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8N1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="582"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="269"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="628" mass="68873" checksum="3D38DB347332E532" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y974</accession>
    <name>A0AAD8Y974_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008328</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y974"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="324" mass="35073" checksum="C6880D25F4F7CCE8" modified="2024-05-29" version="1">MSTAIEEGRDEEEEDEGINLELRPEYQRSLQRRRLNATVALAIGCIILATTVLLKGGSGGRNSDGGLDTRDDDDIFSRSKDLVIDDDAFDDDGGLDESKDWVSFTSPLPPPTPLPTPLPTTFSPTPKPMPVPYVNLCTPPLPSSIEGDGSFTVLDHVELMQDSDDCNSMMDYCNGAISALVIAGSGEIVIAGFPAHSRPRTSESVGEKAGWRVGLVRVFAYSCEYNSYRKLGPDLSPLNPEAVGDLFGTSVVASRDGRVLAIGAKVDNHLDWARTEEDATLVPYVAVHRLVDDGVSQSGNSGERRSRANGRLQGRIRVKRELLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y985</accession>
    <name>A0AAD8Y985_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-hydroxyacyl-[acyl-carrier-protein] dehydratase</fullName>
            <ecNumber evidence="2">4.2.1.59</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_006714</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.59" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y985"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019171">
        <property type="term" value="F:(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01288">
        <property type="entry name" value="FabZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.129.10:FF:000001">
        <property type="entry name" value="3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00406">
        <property type="entry name" value="FabZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013114">
        <property type="entry name" value="FabA_FabZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010084">
        <property type="entry name" value="FabZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01750">
        <property type="entry name" value="fabZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000582">
        <property type="entry name" value="PRK00006.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30272">
        <property type="entry name" value="3-HYDROXYACYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30272:SF1">
        <property type="entry name" value="3-HYDROXYACYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07977">
        <property type="entry name" value="FabA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042283116" description="3-hydroxyacyl-[acyl-carrier-protein] dehydratase" evidence="9">
        <location>
            <begin position="19"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1742149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="217" mass="23326" checksum="2DD83AA98372C759" modified="2024-05-29" version="1">MKLATIILSLYLASSSSAADLPASDAARKLGGKSKSARKLIAEAAEAEAEVEPPPPRSAAEISALTSSVKTIFSLEDIKGILPHRYPFLLVDKVVEYEQGKRAVGIKSVTLNEPHFTGHFPDRPIMPGVLQVEALAQLAGIVFLQMEGASELGAVFFFAGVDGVKWKKPVVPGDSLVMEVEIKKWNKRFGIATATGRAYVDGEMAVELDEMKFALAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAW4</accession>
    <name>A0AAD8YAW4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006688</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1743091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAW4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1743091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="236" mass="26188" checksum="2071A7B08499F720" modified="2024-05-29" version="1" fragment="single">MDVQDYEYYEARAKDVKLEDITSSQLNAYILERLRDNDPDFTHISIGEEYTDERDFVVREGDDLGWLGYFVGRSKELECLKISDLPDSLNIDSFLRGIGHNRSIESLAISIDLGEESFQTLVPFLRNNNSLGDLHFIGFNIGLQCARNIGSLLGQQCSLKCLYFEENNLGDEGLAEIAAALRAQPQIEELGLLGNQNIGRNGCVALGSALEGMRNPGLAMLDLGHTDIDDEGIHAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAY3</accession>
    <name>A0AAD8YAY3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chloroplast protein-transporting ATPase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006399</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAY3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00198">
        <property type="entry name" value="vWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014018">
        <property type="entry name" value="SecA_motor_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052969">
        <property type="entry name" value="Thr-specific_kinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47763">
        <property type="entry name" value="ALPHA-PROTEIN KINASE VWKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47763:SF4">
        <property type="entry name" value="ALPHA-PROTEIN KINASE VWKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51196">
        <property type="entry name" value="SECA_MOTOR_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042062243" description="Chloroplast protein-transporting ATPase" evidence="1">
        <location>
            <begin position="17"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="domain" description="SecA family profile" evidence="3">
        <location>
            <begin position="1"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="518"/>
            <end position="690"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1742802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="723" mass="79305" checksum="845680655B633273" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YB39</accession>
    <name>A0AAD8YB39_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_006555</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YB39"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09272">
        <property type="entry name" value="RNase_HI_RT_Ty1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1742958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="117" mass="13332" checksum="CB4C86E26A553069" modified="2024-05-29" version="1">MEAEISALAHCCKELFPLIDLAKSLAEHFKLEPVESTMSVTIHEDNAAALILGNTLPPGYTPRSKFFHLETIWFREEIARRGINLVKVDTKEQLGDIFTKGLTQVTFEYLRKKLLGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YB69</accession>
    <name>A0AAD8YB69_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ADP,ATP carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_006534</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ADP/ATP translocase tlc family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YB69"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005471">
        <property type="term" value="F:ATP:ADP antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004667">
        <property type="entry name" value="ADP_ATP_car_bac_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31187">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31187:SF1">
        <property type="entry name" value="ADP,ATP CARRIER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03219">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="258"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="287"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="323"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="383"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="417"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="453"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="508"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="551"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="580"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1742937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="669" mass="73914" checksum="E53D0888A63BB41A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBI0</accession>
    <name>A0AAD8YBI0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_005804</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBI0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF27">
        <property type="entry name" value="ATPASE FAMILY GENE 2 PROTEIN HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="276"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="583"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="518"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="535"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1743183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="838" mass="91102" checksum="783ACA053FCA916D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBY8</accession>
    <name>A0AAD8YBY8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBY8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="247"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="329" mass="36256" checksum="1CD48623739702C6" modified="2024-05-29" version="1">MLSAPSVSVSEGTIKATAVVAFVAVLAIPVYHKHIKPKFKGQELDAKKDDDAGRGRRGRLSRRPSVLEELTSVPLVLRAMLWLQCFQGLMLWLSPKIIAEVYGLTDMSPLATMLCEDFGRMWTGLHFGALVSGRKGVSTATVISSGLVFLLLSELKALLNDEYLGGNTPNRVVILIVIKLASLWALEYGPEISIQEGLLAETLSKVIPTQEHIGQFMAFYVALDGACMYFAPYRYAAFWGYAINDEVLRFLTVVAGEGSMMMGAFWFTLLRGEHAWKAYGVAALVYFGCTVDVGFISKTGWFIGEAGVWVDLILSYITIITAQPWTIFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YC32</accession>
    <name>A0AAD8YC32_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005303</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YC32"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1743706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="76" mass="8861" checksum="19061712F50ECE86" modified="2024-05-29" version="1">MRYCNFTEFTPMEASHEDPHTAAIKAKLQSKEWQENAVKNNIFSGCEEPTKTRRDVPLPPIRKFTTLNLGKRQRIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD08</accession>
    <name>A0AAD8YD08_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WRKY19-like zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005575</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD08"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056866">
        <property type="entry name" value="Znf_WRKY19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24906">
        <property type="entry name" value="Zf_WRKY19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="465" mass="49908" checksum="96199A1461EDF5D4" modified="2024-05-29" version="1">MSTKQQSQAKKIVPPNDCGEEEVDDVGALIYRESQLRKAEAAVAAKSKRKSIALNLRTSTRMRTPAINQGLKSLPIPQRKGASKRRKRESALEEDRPRKKMAKKKYRCKCSADGCTNKIQNGGVCIRHGAKRKRYICNSEGCTNNVIKGGVCTKHGAEIKLCSSEECTNNAVKGGVCKKHGGNKRCSSDRCTNFAVKGRVCVRHGANKKICSNDGCANQAKRGGVCMRHGAKKYRYECSADGCMNQAKRGGVCRRHGANSRQCITEGCTNIVVKGDLCIKHGAKVKRCSSEGCTNRVYNGGVCVRHGAKVKRCSSEGCTNKIVKGGVCMKHGAKVKRCISDGCTNHAKKGGVCIKHGAGGKPLCSSEGCLNQVKNGGVCIKHGAKVKRCSTEGCTKQAQKGGVCISHGANRITNDESTAFGSEYEQTTAAQTLPNQRAPRSTVIGQEGRSVPGEVTIICQEIIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YE20</accession>
    <name>A0AAD8YE20_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Abnormal spindle-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_005334</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051295">
        <property type="term" value="P:establishment of meiotic spindle localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007051">
        <property type="term" value="P:spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21223">
        <property type="entry name" value="CH_ASPM_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051185">
        <property type="entry name" value="ASPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22706">
        <property type="entry name" value="ASSEMBLY FACTOR FOR SPINDLE MICROTUBULES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22706:SF1">
        <property type="entry name" value="ASSEMBLY FACTOR FOR SPINDLE MICROTUBULES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="6">
        <location>
            <begin position="696"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="381"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1936"/>
            <end position="1957"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2088"/>
            <end position="2113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2183"/>
            <end position="2217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2237"/>
            <end position="2346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="433"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="2088"/>
            <end position="2097"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="2098"/>
            <end position="2107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="2237"/>
            <end position="2252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="2274"/>
            <end position="2287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="2303"/>
            <end position="2334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="2335"/>
            <end position="2345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1743737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2420" mass="272468" checksum="4066ED84D196E7B9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YE36</accession>
    <name>A0AAD8YE36_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Eukaryotic translation initiation factor 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_005382</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2-beta/eIF-5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YE36"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071074">
        <property type="term" value="F:eukaryotic initiation factor eIF2 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005092">
        <property type="term" value="F:GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Eukaryotic translation initiation factor 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.170:FF:000002">
        <property type="entry name" value="Eukaryotic translation initiation factor 5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045196">
        <property type="entry name" value="IF2/IF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002735">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016189">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016190">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_Zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001:SF7">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01873">
        <property type="entry name" value="eIF-5_eIF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00653">
        <property type="entry name" value="eIF2B_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100966">
        <property type="entry name" value="Translation initiation factor 2 beta, aIF2beta, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75689">
        <property type="entry name" value="Zinc-binding domain of translation initiation factor 2 beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Translation initiation factor IF2/IF5" evidence="7">
        <location>
            <begin position="19"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="155"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="155"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="180"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1743785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="349" mass="39753" checksum="163DA3F0B12FCECB" modified="2024-05-29" version="1">MAKGQIINISGTSPVDDPEYRYKMPKVVGKLEGRGNGSKTVIVNISELALSLHRDPGEVNKFFGTELGAQTTYSDETNRAVVNGHHTDAVLQQAVHKYVEAFVICPNCGLPETDYKIKSGVITHKCAACGAKEMVDMSHKLTNYIWHRIRRRSRMPRRMRRKIRRRTKRRIREKKDKKSKDKKKEKKEKKKKSKDKDGELEDAVGDISLGDDDVEHVDDDNAMATKKFLSEIPMPLLPLFLTKWPTSKWLRPQDPHLCPCRLTTDFFKTKQVAKNAPSISKITQGKTVMERHLISACECLCADEPKKFAVLLKQLYDEDILEEILSWNGLEREGLITLLIVSTKSRGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YE53</accession>
    <name>A0AAD8YE53_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YE53"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000160">
        <property type="entry name" value="Polyubiquitin-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042090682" evidence="1">
        <location>
            <begin position="24"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="54"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="284" mass="30640" checksum="30434308A6839252" modified="2024-05-29" version="1">MVSSKSSLLLAACLLASSQSCSGARLPFLGAAAPLHHSRPSTALNTALHVRGGMQLFVKTLTGKTVSIEIEEGESIEDVKAKIAEKEGIPAEQQRIIFGGQQLQDGKTIDDYNIGDDATLHLVLRLRGGGAVKSAVEKALGRGVFQVDESFVQSNLKGMSEEERELMNMFINQSLGLTEEEAEVKPTATDGRAPALAAYYRISNLPRRTCDTSPLEEVEFNSRSAMPRDRAFDLPGGKGARLVEVEHKSGFGLLGKEETKLTGVYKRGDNRGALLGALKRMRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEA0</accession>
    <name>A0AAD8YEA0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEA0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="193" mass="22856" checksum="3B9B0DF9FE3CD716" modified="2024-05-29" version="1">MDLDGTNVTGDVRDIKETDFTNLNEMFLSKSVYGSNVYCEFDCIADVPSVMQAWHRLSKRIPSLFEKIRQWYLDLESTDQYHSEYHNYGVDPPFYIEPVKVGPRLGWRWINYQKHPCKVNWLDPEPEIPSENDYGARVKYESYVRDLQDIELELQASPFKDCYLPTEEEYCRLSKEFDENRVFSDEEDDSCGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YF25</accession>
    <name>A0AAD8YF25_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005628</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YF25"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="197" mass="22547" checksum="11B1C4C5F244DC2E" modified="2024-05-29" version="1">MADIVITRSTAIDGKERVPDTLVMIMSIHHSMTLTLGLPLVMKYRQLRTVHLLTFNLQWAAALAISANEYCKTLDLKNQKQLWTFRIVNGICFGIMAWMRGIYWLFLCGKLHMRLYEDEEYTMMCVGVMIYTLITGFNVMLCIYPFGKKMLKFGPRSKEMGLVDMDDGEELEDTKKEGGVHPSPSNNSLMEKGDTDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YF40</accession>
    <name>A0AAD8YF40_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YF40"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="281"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="523" mass="56612" checksum="5499F34A4A28960C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFA5</accession>
    <name>A0AAD8YFA5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mismatch repair endonuclease PMS2</fullName>
            <ecNumber evidence="7">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_005482</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFA5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032389">
        <property type="term" value="C:MutLalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.100:FF:000001">
        <property type="entry name" value="Mismatch repair endonuclease pms1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="entry name" value="MutL, C-terminal domain, dimerisation subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.100">
        <property type="entry name" value="MutL, C-terminal domain, regulatory subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="MutL/Mlh/PMS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014790">
        <property type="entry name" value="MutL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042121">
        <property type="entry name" value="MutL_C_regsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00585">
        <property type="entry name" value="mutl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073:SF52">
        <property type="entry name" value="MISMATCH REPAIR ENDONUCLEASE PMS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01119">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08676">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00853">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118116">
        <property type="entry name" value="DNA mismatch repair protein MutL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair protein S5" evidence="6">
        <location>
            <begin position="250"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="MutL C-terminal dimerisation" evidence="5">
        <location>
            <begin position="763"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="423"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="557"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="442"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="465"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="512"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="523"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1743885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1033" mass="113696" checksum="EB5DCF4C6923B9AF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFT6</accession>
    <name>A0AAD8YFT6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004404</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFT6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="606"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="622"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="660" mass="72912" checksum="AA6EFAEEC9DE0669" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YG45</accession>
    <name>A0AAD8YG45_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005044</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YG45"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="283" mass="31524" checksum="41E552AFC1AE7FFA" modified="2024-05-29" version="1">MLQDSTYSKRKEASGQGWQEHFVNQLAASKTQSVGEAVSQCLSYVTLSNFASVDEMQILHQAAMDVKIQSSNSNLQEDTNDGTHVMGATVAAHHNCTRYSVEQLLNSNAKEISALFLHRLLRFLDGSSHWEEEGEEEVCEPIEEIMLELGRMVFGHADWTDSTVKWYTEPDHTGTLHPEPKVNIYDVGGFFKKHEDGMDMTLLVVLNDSFAGGGTAFYCHHDDDNDGESVSKLPDRVERAESGTAIIWGAYMKHMGLPITSGQRSIFVGSFDLEENVENESNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGA4</accession>
    <name>A0AAD8YGA4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002656</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGA4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="822" mass="91247" checksum="06205489922017DB" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGB3</accession>
    <name>A0AAD8YGB3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_002671</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGB3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF15">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042142595" evidence="3">
        <location>
            <begin position="22"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="18"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="427"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="40"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1746064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="499" mass="54749" checksum="545FF77DC2EC22C0" modified="2024-05-29" version="1">MLSSSSSDLLFLALAARLGHSDSSSSSSDDDESGSRNESTDSSSGDGDSSVSIGSVENDDEDEYEQVFIESMQNVKDNEDVRDLCAEGSYGYIQNMTNEDWEQLGRDISNHDHLGSLSITRHALEDENMSFLFRGLTKSNTIKYVTLYENDFGAEGVLAMVPFLQNVDYLEELNLNDNTITSEGFNSVFRALHGSAINYLRCSGCGIDSIKIDNDYIPRNLRILGLCHNSINADGCRELAKLLQRSLLSLELSKNSIDDEGVEILANSLCNSSLLQIDLTQNQISVEGLKLLLKVVNDISSIEATLRSNHTLNLINVVANDDAGGGGDKESEEVQQQINDTVMINRRNRNYPEAAGKEKVIHSQLNSIKRRNLAALLGVDGEVLYSEINCLHLPEVLSIIGETHGQGEIYVALRSSIAALFSTVDRKQCLQQQRAYHRAKLEAIEAEIAAIEGAQENAEVSRGVCNLASGHYTSFPTNELTSSRAVFVQPLGACCYRNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YH69</accession>
    <name>A0AAD8YH69_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aspartyl/asparaginyl beta-hydroxylase</fullName>
            <ecNumber evidence="6">1.14.11.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_003383</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aspartyl/asparaginyl beta-hydroxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.16" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YH69"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062101">
        <property type="term" value="F:peptidyl-aspartic acid 3-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007803">
        <property type="entry name" value="Asp/Arg/Pro-Hydrxlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051821">
        <property type="entry name" value="Asp/Asn_beta-hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46332:SF5">
        <property type="entry name" value="ASPARTATE BETA-HYDROXYLASE DOMAIN CONTAINING 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46332">
        <property type="entry name" value="ASPARTATE BETA-HYDROXYLASE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05118">
        <property type="entry name" value="Asp_Arg_Hydrox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="22"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Aspartyl/asparaginy/proline hydroxylase" evidence="5">
        <location>
            <begin position="253"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1745459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="454" mass="51353" checksum="5C3EAFC41E202FBC" modified="2024-05-29" version="1" fragment="single">PKPTQNPKWLQNGAQLLLGDPILRPYLPSFGCLFLPLLVDDNITMMEALHSFYHNDDQIVLKAILSVFCLGFAFLLWIRPINNHAATATNACNNPSCLRCHSTSQQHAQSFQSNVMMLRRLVQLEPELFRDMRGEIWDEVAIIEQRFESNHHNTSSSSFLKQLLELLTRTRRLITLKKSHDTTNEQNMIPLSPQEGQNPTVFFLQQLEAIPLHNIEACTKQHCPCIRLWKELHLPPNAPPVKLTGDIETLKTHFSVIREELLSAIQTNTATFHPFDDAVYEHANGKEQKQQEQQAEWSSIYLYRQGIKQVDTCKKYFSITTNILETMCPHRMGGCGFGSVYFSKLKQNTKVVEHCGPTNVRLRCHLPLAVPNKTSGSYLRVGEHCVSWEEGKPILFDDSFLHSAVYAGCNDSDGSSISSDQSSGDRIVLIVDFWHPSLSVADRTALGVLYPPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHK7</accession>
    <name>A0AAD8YHK7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004612</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHK7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="152" mass="17283" checksum="0576AD3DAB2621AC" modified="2024-05-29" version="1">MSSKLVKKLLNQTNTQLESNDDTKHQSSSKSRKDAGSRSRTTVTHNITKEEAIQGHIQSILRLDSLVQEHTSTTAQKSFTRRSSDLKLQAKKQRRLKKSGGGASNSRSSSSSFSKQRQQPTFNKDKEKRKKDEEYYSDIARALKKAKKRSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHM9</accession>
    <name>A0AAD8YHM9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Multiprotein-bridging factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_002083</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHM9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="entry name" value="lambda repressor-like DNA-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013729">
        <property type="entry name" value="MBF1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10245:SF15">
        <property type="entry name" value="ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10245">
        <property type="entry name" value="ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1 MULTIPROTEIN BRIDGING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08523">
        <property type="entry name" value="MBF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="lambda repressor-like DNA-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="4">
        <location>
            <begin position="86"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1746739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="125" mass="13465" checksum="9CDFF0FAE51CD76F" modified="2024-05-29" version="1">MPNTNIQTGQDWGAVNVGRSSAGRVAVPKTAHGVTRAKAMGLLATEKKFGAGGNRSAHTASVNAKKIEDSDELKLNKVDKSLSKAIQQARMAKKMTQKDLATRINEKPQVVGEYESGKLFQMVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHW9</accession>
    <name>A0AAD8YHW9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHW9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="27" mass="3131" checksum="6741D49AE2F3ACD8" modified="2024-05-29" version="1">MTSSKEAQLALYVGKGFSMYSREKDRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJC2</accession>
    <name>A0AAD8YJC2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_001361</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJC2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042138053" description="EF-hand domain-containing protein" evidence="2">
        <location>
            <begin position="29"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="68"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="151"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="187"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1747398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="254" mass="29441" checksum="921603304C6E134C" modified="2024-05-29" version="1">MINANAREWCKMVQVVRVVLICVIETLSEMMDRNDEYLGNIHNEWCPRGGASIFATTSTIRRLPKTSFQEAKLRRVYEAKDFDNKGYVSTNDYETWGKIAAEKVGLVMDDEIKGYWVTACQSYFGDTKSFDDWIDYFNAFIENNPDNYEEISRDINVTVFKAIDSNKDGVVSVAEYKAIVTAIFPDLTDDDVEYGFNMIDEDGDGVLSQEEVATAWLRYYYDEEDTKYKHFYGRWDEKSKGGSIWTWLTSSCYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJQ3</accession>
    <name>A0AAD8YJQ3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Soluble adenylyl cyclase</fullName>
            <ecNumber evidence="6">4.6.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_001812</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IUNH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.1" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016799">
        <property type="term" value="F:hydrolase activity, hydrolyzing N-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="entry name" value="Ribonucleoside hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16305:SF28">
        <property type="entry name" value="GUANYLATE CYCLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16305">
        <property type="entry name" value="TESTICULAR SOLUBLE ADENYLYL CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="Nucleoside hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="5">
        <location>
            <begin position="585"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="60"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="142"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="207"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="178"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="273"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="283"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1747849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1915" mass="212875" checksum="0154946E6C57DC30" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJT5</accession>
    <name>A0AAD8YJT5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_003194</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJT5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="99" mass="10464" checksum="48BAC7AEC29AA13C" modified="2024-05-29" version="1">MSTNNGHLRTLPIPLLSPHIIYIKMKLILSLFVLVASANAFAPATTGVISRSVALNVVTGAGGSPAATKEEDLELTTQIILDYVNAQNDEAGIDDSDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJT8</accession>
    <name>A0AAD8YJT8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6817 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001385</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJT8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049202">
        <property type="entry name" value="DUF6817"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37391">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37391:SF2">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20680">
        <property type="entry name" value="DUF6817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041917854" description="DUF6817 domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6817" evidence="2">
        <location>
            <begin position="57"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="299" mass="33696" checksum="80D2805899DACB1A" modified="2024-05-29" version="1">MRRHLQLLLLILISYTFAAASAYHAISKYKAPNANTPPDQVATWKAEDEALHSYITQSVPAVLDHTGSEAFDAHLRGVQAILRYWGAPPHLYNAGLFHSIYGTEGFQGFSIPLSDRDAIRNLIGDEAEKLCWIFCMVDRSTVDETVFNWKLEDVKAGEATNYTFLARPELGRFEIHVNKNEWIDFIELTLSDWLEQVQGAAETTSDLFYWKAGEAYAYRRTAYAKMAEILSHERPDRLSSVVKETVAHVYGTEQSSTRHLVQLRTPPMSDSAKEALAALRSAGEDIPVDFAPQSIRDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJZ2</accession>
    <name>A0AAD8YJZ2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GDP-fucose protein O-fucosyltransferase family protein</fullName>
            <ecNumber evidence="4">2.4.1.221</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_002243</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.221" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJZ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046922">
        <property type="term" value="F:peptide-O-fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11296">
        <property type="entry name" value="O-FucT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019378">
        <property type="entry name" value="GDP-Fuc_O-FucTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31469">
        <property type="entry name" value="OS07G0633600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31469:SF8">
        <property type="entry name" value="OS07G0641000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10250">
        <property type="entry name" value="O-FucT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0294">Fucose metabolism</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1746899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="236" mass="27721" checksum="52378DDDE2C32B85" modified="2024-05-29" version="1">MQEAPVVHFMCDSKMRVRFLTHFYAFLFFESWEQDLFTKRFVRDHLRYADEIQCAAARVVAAIRDRARRRDPTGNSNGDFDSFHIRKLSIQKCMVEADQIYENSKDELQENATVFVATDHKEKPFFKALADHYDLVFLSDFKEELKDVNTNYFGMIDQLVASRGRVFFGCTLQLFRVSSFVCEDITRRRIRWRAGIAASFLNPITIRARKRNRCINLTRLCNFLITHVSFQSAGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKB1</accession>
    <name>A0AAD8YKB1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">holo-[acyl-carrier-protein] synthase</fullName>
            <ecNumber evidence="1">2.7.8.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_001931</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.7" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKB1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="entry name" value="4'-phosphopantetheinyl transferase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050559">
        <property type="entry name" value="P-Pant_transferase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12215:SF10">
        <property type="entry name" value="L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12215">
        <property type="entry name" value="PHOSPHOPANTETHEINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="4'-phosphopantetheinyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="4'-phosphopantetheinyl transferase" evidence="3">
        <location>
            <begin position="183"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1747968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="404" mass="45929" checksum="7EC654FFAE543710" modified="2024-05-29" version="1">MKLSIVRLDHSIAEIKTTSPGIEIESLSRAVFEYLSCKSAIEDPITSRWNPFARQKASCNSSLKETLIKSIMRYFKAHDRWTAFSSLLLKSIAFHRHIDPNVPIDVADKMLPVIDLPRTKFNRPFLPQTLAEKTSTRVADEEVEESRESVMNVSHQFPYVCMIQKQGSDHTHASSTQLQYDMIGCDLVIFEARLNKYSPTITAFLESFVGCFTTSEWQAISNDARSLPRSDDSLLKEFFLRWAMKEAYTKALGVGLNIDFDSFETRLIGHDVDSTDIEGVWIPRDGIWESITPDIQQNNPNEQVEHQFSFVGQVIRTRDPNSDYWVFSFIPLVEEVVENSIQSEETASSGCICICKGPFNEEADAATSSDSKQHRIIVENLSLLDLIQLHGMKSTDIDVMRQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLH3</accession>
    <name>A0AAD8YLH3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_001435</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLH3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.20">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042277251" evidence="3">
        <location>
            <begin position="23"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1747472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="267" mass="29387" checksum="98C014A6DE3A1BBE" modified="2024-05-29" version="1">MKTTSSVFSAAILLSAASAARAASDNQCFDFTPMSSVSNYLGATLDYSVADRICCHNHKFAEYRGYLAAPEVDFFGRLDPSVETVFYDSVCGLPLFIAPRGRTFDDFKKESLKHGWPSFRPEEMISENVIIHDDGRMESVCLSHLGHNLPTGGVDRYCIDLVCMAGEPLSAGDERNQILQYMHQEQIINATELNTTSYTSSAEQYSGKTSNATAIIISVAVVGLFLVVVAFVCCEKPGWKRKGDEIQVGSSETSTSIHEDDEENEIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLT3</accession>
    <name>A0AAD8YLT3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001822</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLT3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="226"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="372"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="288"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="116"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="231"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="395"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="407"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="428"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="441" mass="47076" checksum="BD519F12D1B89692" modified="2024-05-29" version="1">MVTKTTDSAPAHAAEPALPPQQSVLNSEHDSVDAAKEVPKQQQQQQQDNKLDTSPLNPAAGDEKFEAKKAPAAAAAAPKAPDESGATSTKIQPVTRPAILSPPAIPAAASKPLATPHSSTPKVPTKSATRQRKALPPIAGHSLADPTVIAGVNSIIALLQSYGPLSYEQLKFNMATQLVPLNQPVKSDTKDKLQQVLGILVELGIIHQVDKASLGKNGNLMTKSAAKKLKEKKEEESSAAKEKEGESGVVPKSGTKSVDRPDLNPIYCFGNGIPRMDVVLPSQILSDIKESGEEVLRMQKRIEILRNALREIDETASEDKGKDDKVGNKSYEKAKGVLKQLLELHPEVVQDPVYAAALRMFKLKEGIPGLNEEDEERTLQNIHGSSGGKLKKRASASSLGSAEGSGKKKRKKGRPRKNSSANIVEKVATSSSVVKANASWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YM61</accession>
    <name>A0AAD8YM61_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mitochondrial inner membrane protease subunit</fullName>
            <ecNumber evidence="6">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_001858</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.</text>
            <dbReference type="EC" id="3.4.21.89"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peptidase S26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YM61"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009003">
        <property type="term" value="F:signal peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06462">
        <property type="entry name" value="Peptidase_S24_S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.109.10">
        <property type="entry name" value="Umud Fragment, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019758">
        <property type="entry name" value="Pept_S26A_signal_pept_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019757">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Lys-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019756">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02227">
        <property type="entry name" value="sigpep_I_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43390:SF1">
        <property type="entry name" value="CHLOROPLAST PROCESSING PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43390">
        <property type="entry name" value="SIGNAL PEPTIDASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="LexA/Signal peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00501">
        <property type="entry name" value="SPASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00760">
        <property type="entry name" value="SPASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00761">
        <property type="entry name" value="SPASE_I_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042176034" description="Mitochondrial inner membrane protease subunit" evidence="7">
        <location>
            <begin position="23"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S26" evidence="8">
        <location>
            <begin position="177"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR600223-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1747895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="390" mass="43196" checksum="660BA898B98C6D0E" modified="2024-05-29" version="1">MKGYYCVLSIFSAACCCQAVGAFAPSHYAATQRRRILHQRAVQNDAAEEQPQKNIFNTLRSNLKTAADEGFGTRARNVGDTMKIDDTVVPLCSNLEKRQSLADRGVYPGVEYLICDIDSEEEVDRSVSIRPAYPLRDYLERSDWPVTVAVADVPLWLAKATYEAGTAVGTLMLAGTYLSIAAILASFIRIVVVPSESMEPALQPRDVVLVTRSILPPRNGDVVFFNPPKELDEAIANSKVGKAAAAENVQIVSTKGKQFLKRVVGVPGDRVGVFNSNPYVLLECIGDDCTYRVDRTGEYSRPDMFDDESWNRISPTINTNIHEDTERLDRGEYFVAGDNGFRSVDSRVWGPLKKKYLFGTAQWVIFPANHFGPIQPGPFSVEKGLTTERN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPH5</accession>
    <name>A0AAD8YPH5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000849</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPH5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="821" mass="90998" checksum="D3DEE914308785ED" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D524</accession>
    <name>A0AAD9D524_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MAP3K-like serine/threonine kinase</fullName>
            <ecNumber evidence="3">2.7.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D524"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050167">
        <property type="entry name" value="Ser_Thr_protein_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257">
        <property type="entry name" value="SERINE-THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257:SF958">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE WNK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="419" mass="47688" checksum="FDEDE69ACA1DB49A" modified="2024-05-29" version="1">MKYLSPNKTSPPPPPTEEEEETINYVSKFERGIADLAMEARYLSVLSHENIVTLWFVSEGSLEEVFNCGDEGGGGGNGSGRRRRRSSVKHHGNNDSSSNSNNAEGGRHHHQHGYFLLLDALHETLHQRISHSYIPQVVDTPLRIYQTNKKAYSNNTHIAKVQLAKRLSSLKSIALALQYLHEDCNLIYRDIKPSNIGFHRRYDGGDGSSCTCGHVESSGDDQQQSSKCTCNYTDIPKLFDFGLAKELKSKFRKAHPSHSHDDPPTFKLTSATGSRRYMSPEVALREPYNHKADVYSFGMVVYQISALVVPFHGLAMKNHEQVVAREGLRPDVTIPSKESSVRRTRDFRRHYSKEKDRGKKILMLSKRARCVWPEGLNALITECWDDDMRKRPEMREVVERLDACIEELNKRQRHRELGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D526</accession>
    <name>A0AAD9D526_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Calcium-transporting ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_014873</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18105"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D526"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000028">
        <property type="entry name" value="Calcium-transporting P-type ATPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000065">
        <property type="entry name" value="Sarcoplasmic/endoplasmic reticulum calcium ATPase 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08282">
        <property type="entry name" value="Hydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00121">
        <property type="entry name" value="NAKATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042252990" evidence="11">
        <location>
            <begin position="20"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="860"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="934"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="12">
        <location>
            <begin position="52"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1734366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1087" mass="117268" checksum="A089B66F1877C23F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5J2</accession>
    <name>A0AAD9D5J2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heat shock factor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_015550</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000045">
        <property type="protein sequence ID" value="KAK1733695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5J2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF206">
        <property type="entry name" value="HSF-TYPE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="5">
        <location>
            <begin position="2"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="121"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1733695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="183" mass="20536" checksum="D0D36F33AAE6E1D5" modified="2024-05-29" version="1">MPHGRAWKVKNKELLVEEVIPKFFGQSKFASFARQLSGWGFKSTIVSICLYSNFILIALTNHFIRLCTDFGCYYHECFLRGHPRLTALMRRVSTGQGKVTPNMHSEPDFYLIAQQYPLETPADVPDRDNKRVVSKVAKASVSGRQKSQCPGDSDVGDEASGYKEDDDPLMTRKTAEPGMDGIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D684</accession>
    <name>A0AAD9D684_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Esterase, PHB depolymerase family</fullName>
            <ecNumber evidence="4">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_014937</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D684"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050955">
        <property type="entry name" value="Plant_Biomass_Hydrol_Est"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037:SF5">
        <property type="entry name" value="FERULOYL ESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037">
        <property type="entry name" value="UNNAMED PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042271588" evidence="3">
        <location>
            <begin position="21"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1734430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="352" mass="39244" checksum="D3385057FEBA9332" modified="2024-05-29" version="1">MFLPTIISITFLFGGLFTDALPSEGRKHNFLRNGKLPIPTRDSTHVITVTVEEDNTSLGGFERPKFIEREFTVFDPVHKRKGNAKRPLVLAYHGVMSDSETMRQLTQFDREAKDRGWVAAYPQGEWKFSEKMTNWNGAGCCSQGQDDIAFTKDMIDYIVKHFNVDENEVYVTGVSNGGFMVYRLLCEMGDRENGKPWISAASVHSGLLGAWQADFSSCSISTDTSLVHFHGLADPVVNITGKPEGKQELLPFAPVTNAEWKSVNASIDYVAEAMCGSNAITSTSNPTESTTCHQMCDGKVEYCMVEELQHMWSGCSDESLHMYDPNHATNVDATKYFADSFARHSSKKETNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7F8</accession>
    <name>A0AAD9D7F8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphodiesterase</fullName>
            <ecNumber evidence="6">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_013837</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="6">Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cyclic nucleotide phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7F8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023088">
        <property type="entry name" value="PDEase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023174">
        <property type="entry name" value="PDEase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00387">
        <property type="entry name" value="PDIESTERASE1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00126">
        <property type="entry name" value="PDEASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDEase" evidence="8">
        <location>
            <begin position="324"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="547"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="189"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="547"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="397"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="397"/>
            <end position="401"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="401"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="440"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="441"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="441"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="441"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="639"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="639"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="690"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1735674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="747" mass="84312" checksum="4C08E75DCD782314" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7R4</accession>
    <name>A0AAD9D7R4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NADPH oxidase</fullName>
            <ecNumber evidence="5">1.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_013391</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.3.-" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000031">
        <property type="protein sequence ID" value="KAK1735944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7R4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF153">
        <property type="entry name" value="SUPEROXIDE-GENERATING NADPH OXIDASE HEAVY CHAIN SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
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    <keyword evidence="1 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="198"/>
            <end position="222"/>
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    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
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            <end position="274"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="280"/>
            <end position="309"/>
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    </feature>
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        <location>
            <begin position="321"/>
            <end position="338"/>
        </location>
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    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="677"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="43"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="73"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="85"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1735944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="826" mass="93655" checksum="0394DE896B4B8570" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7V5</accession>
    <name>A0AAD9D7V5_9STRA</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013276</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
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            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7V5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="Formin_homology_domain"/>
    </dbReference>
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        <property type="entry name" value="FORMIN-J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="508"/>
            <end position="529"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="761"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
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        <location>
            <begin position="137"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <end position="210"/>
        </location>
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        </location>
    </feature>
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        </location>
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        </location>
    </feature>
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            <begin position="823"/>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
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        <source>
            <dbReference type="EMBL" id="KAK1736140.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7Y4</accession>
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    <gene>
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        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
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            <taxon>Skeletonemataceae</taxon>
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    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="5"/>
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        <property type="protein sequence ID" value="KAK1737561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7Y4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="transmembrane protease serine 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
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        <property type="entry name" value="AT26814P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Trypsin-like serine proteases"/>
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    </dbReference>
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    </dbReference>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0843">Virulence</keyword>
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        <location>
            <begin position="1"/>
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        </location>
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    <feature type="chain" id="PRO_5041986533" evidence="3">
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            <begin position="20"/>
            <end position="220"/>
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    <feature type="domain" description="Peptidase S1" evidence="4">
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            <begin position="26"/>
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        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAK1737561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="220" mass="24803" checksum="300870202CF248C5" modified="2024-05-29" version="1">MNSMLWLLYYSTLIAQALASSHRDLIINGTIAPQQRYPYAVYLQDNDFPFCGGSLIAPDVVLTAAHCIPEDDYIGNITVMEGEHNLTDTELGDVVRIRENVIHPLYQEENEKDFDIALTFLERPTAIERDSLVHLNRDNSYPPDDTIATYLGWGVVNSKGEASNILREVDVSVMTNEECNRINGTVFDKFFFSMSGHITPSMMCTFAEGKDSCQRDQVVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7Z1</accession>
    <name>A0AAD9D7Z1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MORN repeat-containing protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_013199</name>
        <name evidence="4" type="ORF">QTG54_013893</name>
    </gene>
    <organism evidence="5 6">
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            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
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        </lineage>
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    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="protein sequence ID" value="KAK1735279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="KAK1736063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7Z1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23084:SF263">
        <property type="entry name" value="MORN REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23084">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="321"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="259"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="202"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="345"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="361"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1735279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1736063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="376" mass="41024" checksum="FE7168B0919BE890" modified="2024-05-29" version="1">MSDRTNTNGENNNVSWDSHLVAVLTYDRNSSASGVNRTNGQTDEMADGKAHGTVTYADGSVYTGMLEEGNKPGDFGTVTYVGGSAYTGELKDGKPYGFGTMTYHDKSVYVGQWKAGERSGSGKSTAVMMTSDGKHTVSIDKSEWSTNNFSPGRPAMADNEDRVAERHPFTPTNLFGSATKAQANESLATKAQLDEISPENAKSTNSSSSTKSMNSLLNAVSMEHEERIEKTKLIENTLDQHGAFIHENRGDICLLNKSLAEQEANVRELRKKVDEGVEEREELKNAVNELKSTIDVMTSSQKEEHKTKVAFACANEYFPIPARDSAKKPPADAKKPAVAKKQDENSQPVNRTSTSSAKKSTPFRRSRRKSACTSEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D853</accession>
    <name>A0AAD9D853_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012858</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D853"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1736258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="34" mass="3787" checksum="5258A006026DC0FB" modified="2024-05-29" version="1">MVSHSSSQTSDDSLMRFFRNTSAVWPYSTASSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8B0</accession>
    <name>A0AAD9D8B0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012552</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8B0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="81" mass="8119" checksum="27175449240ED862" modified="2024-05-29" version="1">MKYGSTVIDYMIGGGIAGALFKGSAVRTPTGARLDASIMGNYSASSVSTAMKGKPLSGILPGAALGLLAGVTIVTMDMHKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8S1</accession>
    <name>A0AAD9D8S1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012318</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8S1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018790">
        <property type="entry name" value="DUF2358"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31094">
        <property type="entry name" value="RIKEN CDNA 2310061I04 GENE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31094:SF2">
        <property type="entry name" value="RIKEN CDNA 2310061I04 GENE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10184">
        <property type="entry name" value="DUF2358"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1736873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="266" mass="29230" checksum="C0E0AEFED6785373" modified="2024-05-29" version="1">MRTLSLLVTIAAASISDQNNNMVAALSTISKSSSSSRIRNPPPSPLFPLLESSTVEKEHISLPGSSDNNSNNLSPFLQEMVDEQRELQMNVGKAMDTLRKDYPDFLSRTPDYSLYHENISLKASDGQIQLSKLTSYKKALGLVRSALSLVYDADRSIIQSRMVYDPTRTELRVSYNAMLVPKIMGVTGRTVHVDGISIYAFDLSASVDREGKKNEGAGKIREHRIEKLLVNGAAMQPPYFNNFGLEALVGQRSGALVGAGAWSFEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D943</accession>
    <name>A0AAD9D943_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycerol-3-phosphate acyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010672</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.15" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D943"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004366">
        <property type="term" value="F:glycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006655">
        <property type="term" value="P:phosphatidylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07985">
        <property type="entry name" value="LPLAT_GPAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1130.10">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016222">
        <property type="entry name" value="G3P_O-acylTrfase_chlp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35695">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35695:SF1">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042234570" evidence="1">
        <location>
            <begin position="24"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="2">
        <location>
            <begin position="223"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="456" mass="49605" checksum="9C3AE7A4F1CC1EC4" modified="2024-05-29" version="1">MKFSSSILSAALLVSASCSSAAAFSTHQRTLSSSSIMRTSSSSTTTFLASTTEKSTECSSSTTTTTTITPEFAGARDQAITTLKAQLPPEALSTLEQPLTHFISEYFQSLSDSAAAGTKNPDGSDVTPQQAVKNMLTTLSYGLKYGLGKDKFIFENVRHMALRGADFNDTSVIDSRYEEDSLKEKLGPDVTTDFYAAGCEFFRPSMDLEHSVVLGQDNLKQAREQIDAGENVIFLANHQSEADPQVVSCLFETVGKEMGDLAAHVTYVAGHKVTTDALAVPFSMGRNLLCIHSKKHIDADPETKPAKSRQNMTAMNSMLKGLKEGGMAIWVAPSGGRDRRNVESGKIPIAPFDQKTVDMFRLMGNKSKVPTHFYPMAMVSYDLCPPPDFVEAGVGEQRNVRFTPIGIAICDEVPNVGGAEKRHLFTEKAEEECIAGYTDLLKGLKMDKYIPEEYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D965</accession>
    <name>A0AAD9D965_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">PAN2-PAN3 deadenylation complex subunit PAN3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_010732</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D965"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031251">
        <property type="term" value="C:PAN complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008143">
        <property type="term" value="F:poly(A) binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.3700:FF:000001">
        <property type="entry name" value="PAN2-PAN3 deadenylation complex subunit PAN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.5160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030844">
        <property type="entry name" value="PAN3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041332">
        <property type="entry name" value="Pan3_CK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12272">
        <property type="entry name" value="DEADENYLATION COMPLEX SUBUNIT PAN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12272:SF11">
        <property type="entry name" value="PAN2-PAN3 DEADENYLATION COMPLEX SUBUNIT PAN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18101">
        <property type="entry name" value="Pan3_CK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="183"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="19"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="83"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1738702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="606" mass="67268" checksum="F74B59D7B536A415" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D993</accession>
    <name>A0AAD9D993_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF924 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D993"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.320">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010323">
        <property type="entry name" value="DUF924"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06041">
        <property type="entry name" value="DUF924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="213" mass="24418" checksum="A180F19374CC7E8A" modified="2024-05-29" version="1">MMILKPTVLRAAPLLSRMMMMSSSSFSTRNDTIIGSSSADEVLKFWFEDLSPQQWFIQSDQVDTTIRNKFLDTHNKAAAGELDNWRKDARGSLAEIIILDQFSRNLYRNTPQAFAQDGMALVLAQEAIGKGFEDDLSTEQVQFLYLPFMHSESLVIHERAVELYTALGMNLEFEMKHKAIIERFGRYPHRNAILERESTPEEIEFLKGPDSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9E0</accession>
    <name>A0AAD9D9E0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA mismatch repair protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_011819</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the post-replicative DNA mismatch repair system (MMR).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9E0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032301">
        <property type="term" value="C:MutSalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="entry name" value="MutS, connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017261">
        <property type="entry name" value="DNA_mismatch_repair_MutS/MSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF148">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55271">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="8">
        <location>
            <begin position="1041"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="29"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="156"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="55"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="187"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="226"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="238"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="293"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR037677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1737533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1197" mass="131986" checksum="C6784FC183E1BE3C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9E2</accession>
    <name>A0AAD9D9E2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cyclin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_011638</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000024">
        <property type="protein sequence ID" value="KAK1737654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9E2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000093">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0195">Cyclin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="3">
        <location>
            <begin position="51"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="270"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1737654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="306" mass="35587" checksum="29E4E504B159C93F" modified="2024-05-29" version="1">MGYHEKQQLWWNFSMAELGSLFRKEQSTYRYKIHPEWHHSISIHWRHKICDWCYEFIDHYNFDREVVGVAIYYFDRYISSQTSCEGVHTKDKFQIIAVTSLFLAIKLHSMSENSLVESRSQALARLLYDHVDPQEIYEMEMNILVLLDWRLNPPTLHQFAINFSQLHPLGDCCSTTTSYLYEATRYQVELAIFSPELLATFTSSVIAYAALKNAEEKITVDNPHILTPDMNQSFEALMTDPTMTMTLDSTAVARCQLSLKRLCPQLPGLDEFSDTDTDDRDIQPDYYVQEDTPDPASISPLNVAYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAI0</accession>
    <name>A0AAD9DAI0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAI0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="521"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="565"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="521"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="540"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="565"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="577"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="853" mass="98816" checksum="C7D6AC37FDCF8071" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAT8</accession>
    <name>A0AAD9DAT8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Translocon Sec61/SecY plug domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010244</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAT8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3370.10">
        <property type="entry name" value="SecY subunit domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002208">
        <property type="entry name" value="SecY/SEC61-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023201">
        <property type="entry name" value="SecY_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019561">
        <property type="entry name" value="Translocon_Sec61/SecY_plug_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10906">
        <property type="entry name" value="SECY/SEC61-ALPHA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10559">
        <property type="entry name" value="Plug_translocon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103491">
        <property type="entry name" value="Preprotein translocase SecY subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="Translocon Sec61/SecY plug" evidence="2">
        <location>
            <begin position="38"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="119" mass="13921" checksum="6FA20772AEC579C8" modified="2024-05-29" version="1">MRFLHLIRPVMCVLPEVASPDRKIPFREKVLWTTITLFIFLVCCQIPIYGVQSAKSSDPFYWMRVILASNRGTLMELGISPLSPRDLSCSYWREVGLLRLITMSRRIVHCLRAQNYLEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBV1</accession>
    <name>A0AAD9DBV1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MBL-fold metallo-hydrolase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBV1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42773:SF1">
        <property type="entry name" value="METALLO-BETA-LACTAMASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42773">
        <property type="entry name" value="METALLO-BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13370">
        <property type="entry name" value="Fer4_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042155728" evidence="1">
        <location>
            <begin position="29"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="2">
        <location>
            <begin position="169"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="407" mass="44942" checksum="1C1DA6301BEA1937" modified="2024-05-29" version="1">MKSSLFVLRSGAALHLVLLGSVTLPAASFSCISRIRTLSSAHSQPLRTAPQRLDENVQGILYVNDRCINCAACSNFAPNVFERGPKLKHIVYKQPTVQNKNELEEARAALAACPVAAIRVESKVTDSDAELKRALSIQPNGDALFPRQIISEIDLGVFYLGHHNEASFGAIPYLVRGKSPYSIDISVMVDVPRFSRSAVTAVKSLSPSGPDYLFLTHVDDTADHNKWVEEFPTMQRIFHAGDLGRHNWIGDTTLENVEILLKGNVEDGAKELMIWDINGNQMDEMQPLQEEEILILHTPGHSPGSISLLFRPKSDSVHNCNGILFTGDTYSWTTRDGGHMSGFPRYGNDLPEQAQTLKLLGELSHMWDIIAPGHGHLRSYTTLKGEENESKTKGDDIDIAVSELLSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCS6</accession>
    <name>A0AAD9DCS6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Recoverin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_006438</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the recoverin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028846">
        <property type="entry name" value="Recoverin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055">
        <property type="entry name" value="CALCIUM BINDING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055:SF178">
        <property type="entry name" value="NEUROCALCIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0519">Myristate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="922"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="1578"/>
            <end position="1613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="62"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="189"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="283"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="363"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="425"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="592"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="110"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="283"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="386"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="592"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1742841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1693" mass="182168" checksum="0D9B8250B6B621D2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DE83</accession>
    <name>A0AAD9DE83_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DNA-(Apurinic or apyridinic site) endonuclease</fullName>
            <ecNumber evidence="10">3.1.11.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_007080</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="6 8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6 8">Probably binds two magnesium or manganese ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.2" evidence="10"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DE83"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003906">
        <property type="term" value="F:DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008311">
        <property type="term" value="F:double-stranded DNA 3'-5' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09087">
        <property type="entry name" value="Ape1-like_AP-endo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004808">
        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020847">
        <property type="entry name" value="AP_endonuclease_F1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00633">
        <property type="entry name" value="xth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748">
        <property type="entry name" value="AP ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748:SF6">
        <property type="entry name" value="DNA-(APURINIC OR APYRIMIDINIC SITE) ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00726">
        <property type="entry name" value="AP_NUCLEASE_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51435">
        <property type="entry name" value="AP_NUCLEASE_F1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 6 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="9">
        <location>
            <begin position="18"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="9">
        <location>
            <begin position="157"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="5">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="325"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="325"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="7">
        <location>
            <position position="292"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA substrate" evidence="7">
        <location>
            <position position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1742515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="336" mass="37963" checksum="CFC28EE711272022" modified="2024-05-29" version="1">MEPETAMTSKGSYTFTVISWNVAGLRAFIKKQPDALANLAERYQADVICLQEHKLQDVHLDDPKLKIREHFEEKLGGFESHWSYSTTKKGYSGTAMFIRKRGGGDDASKKGKKQAKIGAFFTSKNKEGDEAAKGDSIGDIPVSHLQPLNVMTELGLPKHDGEGRTVTAEFPLFHLTNVYVPNSGQKLDRLGYRTEEWDTDFLNKMQQLEKGKPVIWLGDLNVAHNEKDTWNEGAKHLVKSAGTTPQERASFDRQLGAGFVDAFRHLHQDAMGHYSYWSQRAGNREPKGLRLDYFICSKDLMEDDDDRKVVVRNSFMVPDELGSDHCPIVLEIEMKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DER6</accession>
    <name>A0AAD9DER6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WRKY19-like zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006667</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1743070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DER6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056866">
        <property type="entry name" value="Znf_WRKY19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24906">
        <property type="entry name" value="Zf_WRKY19"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="363"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="414" mass="43765" checksum="B6EA8514EF29C382" modified="2024-05-29" version="1">MSSSSSVVVIGGPPADNKSAEERTQIRFNDDDSFSVIDSLGSLAQDRNVDEEEESSSSGESEASDAEDKEEASTSSREDNQQQQPVPAQKITAAVTPTPPKPKAKPAKQKTQPPTAAQRQKAPRKNKQPAASSPPLAAVDDDDQTSVALRISGGGKGGRAARANKRKVEKQASTSTVEAVAKRTRTNQQSSSSSSTTTATTTTKVAAAATTTTTTTKRSRKTCSITTCTTQVRNNGLCQKHGAKPKRCTFHSSCTNQVINNGLCIRHGAIAPKKKTYARKVCEVDDCPNFAKKGGVCIRHGATQARKRCGFEGCLRQEQKGGLCFRHGSQQVLLCGEVVTAAEAEGAVCTNTTAAAATARKYKTCSKEGCTKLAQNGGVCYSHGAKVKKCSSEGCTNNSKRRGLCKKHGAYSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEX6</accession>
    <name>A0AAD9DEX6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_004412</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEX6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000011">
        <property type="entry name" value="Putative ABC transporter ATP-binding component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF15">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="36"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="ABC-transporter extension" evidence="6">
        <location>
            <begin position="182"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="299"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="36"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1745121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="343" mass="38782" checksum="67C3E883402D3FF5" modified="2024-05-29" version="1">MKALAAKSIPIPASLDMYFLDSEYPARDDITALQAVMESNDEIAHLEEKANQLNDAMAEADEAQQTEIQTSLEAIYDRLDQLDASTAEARATTILHGLGFTIAMMNQTTCEFSGGWRMRVSLARALFLEPEFLLLDEPTNHLDMDAVLWLEDYLSNWNKILFFVCHSQDFMNSVCTHIVRLDMTYKKLRYYSGNYDTYVQTRRDQDMVQMRQYEAEQRDIAEIKDFIARFGHGTVKMVRQAQAREKLLAKKLEEGLTSQPEVDPDWDWSFPDAGHLPVPVLAIENVSFNYPGGKELYSKVDFGVDLQTRVALVGPNGAGKTTLVKLMTGDLNPTRGKSRGTSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGQ1</accession>
    <name>A0AAD9DGQ1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Solute carrier family 40 member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_003333</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">May be involved in iron transport and iron homeostasis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGQ1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005381">
        <property type="term" value="F:iron ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009716">
        <property type="entry name" value="Ferroportin-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11660">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 40 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11660:SF57">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 40 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06963">
        <property type="entry name" value="FPN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041901641" description="Solute carrier family 40 member" evidence="7">
        <location>
            <begin position="16"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1745409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="97" mass="10974" checksum="67649FD51CA37BF0" modified="2024-05-29" version="1">MLILGVVLSRVGLWANDLSIFQLTQRTVDEHVRGVVGGSQYSMNSFFDLLHFSLGIFFSDPSHFYVLCLIGYSAVITAFLLMLRGVYFSPAFRNMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DI04</accession>
    <name>A0AAD9DI04_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_000465</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DI04"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="195"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="292"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1748526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="429" mass="46881" checksum="23DFE25EE9AC8B43" modified="2024-05-29" version="1" fragment="single">MHHQVLQSQLDRERRAAKKRKKAKKAKAKSYVPPSIPTNETGSVDCKRRGSFDESVLTRTSSCSSNLDDGEVVNDMDLVFGPQSPYHPTKRKDIWDHVVRIAKFDHESKRLVNLMAPYTLTALICNMFAIIDIAIISSVLGAESLSAFLVTGYFLSMVCKAAKGFTDAQATLCAHAVGAGNYFLAGQYIQLTQMVFVLTGVLPLLIMGSSMYQVLVWLDVSSHVATLGGNFATIQAIALLVGGFNDAQTQFLSAIDPSISSNAIEMLMHASYTAGIAAYLYDNANATLIDLAWMKCWIAILFIPINFIVLSSRGWLDLCWVGMIRSNALKNREAVKQMLKTGIPLGIGSLIRESEWVLMVLLASRIGTDDVATFAVIRRTFDIFSSLIEGLCCGAELRCAYHMGTGRQVHAARSAYKSLIIGMSVGTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIU2</accession>
    <name>A0AAD9DIU2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sel1-like repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_002584</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIU2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="150"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="426"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="690"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="700"/>
            <end position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1747240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="711" mass="80101" checksum="A768B2A89DFA5C7F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIV7</accession>
    <name>A0AAD9DIV7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_000811</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIV7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000192">
        <property type="entry name" value="CTD small phosphatase-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011948">
        <property type="entry name" value="Dullard_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02251">
        <property type="entry name" value="HIF-SF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="10">
        <location>
            <begin position="228"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="57"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="122"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1748872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="442" mass="49003" checksum="1EA8D42B5206726D" modified="2024-05-29" version="1">MMKTHISQQHLTVHMAYDHELTAAAVYNNSASDYSDPLRAEKALSIGISRTWSGDDENRLRMKSAQTPQGVRGQSDLRSPGMKKTPMAINAPKLSAFDSEEGGDHADDTNEVVIPDFITQTDRHGVASTPRSASAVQAARQMHPSGPEPNLHVEGGTLVEDSKSDDDDACESLLDSLRMMCCCFLQDSDAIAATGDTKDTHTFTEEDSALRNGNDPNRIKLLPALHSDDHGKKCLVLDLDETLVHSSFRAVQGADFVIPVQIEDVVHFVYVAKRPGVDEFLIEMAKHYEIVVYTASLNKYADPLLDLLDPQRVIRTRLFRESCVFYEGNYVKDMSLLNRDLSQAIIIDNSPSSYLFHPENAIDCGSFIDDPNDRELDQIGKFLVGIKDVEDVRGTANLPDEIMHNTLKIAVHHEKLWSLLGLDLKLSVGVPLIVEIAGFYKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIW0</accession>
    <name>A0AAD9DIW0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">homoserine dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_001757</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the homoserine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.3" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIW0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004412">
        <property type="term" value="F:homoserine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001342">
        <property type="entry name" value="HDH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43331">
        <property type="entry name" value="HOMOSERINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43331:SF1">
        <property type="entry name" value="HOMOSERINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00742">
        <property type="entry name" value="Homoserine_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homoserine dehydrogenase catalytic" evidence="4">
        <location>
            <begin position="209"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1747794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="429" mass="46528" checksum="727871DC4A01309B" modified="2024-05-29" version="1">MKEISLVLLGFGSANRTLAQMLLDKSEKDNSCRQCLRVVAPGGTSTSELVPWKVVCIITRRHGRVCVPHSSKSEINVEEALERIGAGGILDATLVRNTNEATTSTAHSTTTDDTIKLLNELGKTQTANIVVEAIPSNPKSDGEPAISFIRTALQAGMHVASANKCPLTHTRNDKETYFELQGIAKRNGKIYLHESAVMDGVPIFSFWDNLPGVTCTKIRGLLNSTSTMILSRIEGNIDKVVESDGKVEHVGETFEEALEAAKKVGIVEEDESLDIDGWDAAMKLRALCVFLSSSGNLSLPEDHDVIVPPLEAIPRDSISQIDPELICTEFRASRKKVRSVASAELVDLPSDPAIGRHHPVKSWKMSVENEFLSQSDPLYNLNGSSASVQFSTDVMGPISVVSQDPTLMDTAYGLFADVVRIASQSINNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIY7</accession>
    <name>A0AAD9DIY7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_002597</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIY7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="4"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1747253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="309" mass="34500" checksum="99FD29755278BB7F" modified="2024-05-29" version="1">MMCCAACGAAEADHIKLKKCNACYLVKYCSVKCQKEHRPKHKRECKKRAAELRDEILFKQPESTHLGDCPICFLPLPIDNDKSNMMACCSKTICNGCDRANQIREFEGKLLRKCLFCRTAAPKSQEEAARIQMKRIEVNDPVAMRRMGFERQEKEDYDGAFEYFTKATALGDVGAHFNLSLLYHEGKGVGKDKKKEVYHLEEAAIAGHTSARHNLGCLEAGNGRADRAMKHWVIAANLGDDGSLEILKDAFGKGLVISKEDFAAALRAHQAAVDATKSPQREVAELAREELEKIKLQREREVVAGNLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJ16</accession>
    <name>A0AAD9DJ16_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Phosphatase</fullName>
            <ecNumber evidence="8">3.1.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_000991</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJ16"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006384">
        <property type="entry name" value="HAD_hydro_PyrdxlP_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016965">
        <property type="entry name" value="Pase_PHOSPHO-typ"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01489">
        <property type="entry name" value="DKMTPPase-SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20889:SF12">
        <property type="entry name" value="LP01149P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20889">
        <property type="entry name" value="PHOSPHATASE, ORPHAN 1, 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06888">
        <property type="entry name" value="Put_Phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF031051">
        <property type="entry name" value="PyrdxlP_Pase_PHOSPHO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="30"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="32"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR031051-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR031051-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR031051-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1749052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="304" mass="33979" checksum="E429C55F583371B1" modified="2024-05-29" version="1">MTAAAAADQLQQDMQSLSENHSVETIFVWDFDWTIINCNSDEYVPAGFLGDEEVAKRITAEMKEHGPTKWHECVANLINACMLEKACSNDDILEKAAEMPYLVDVKQALTDVANNKHCRQAIISDGNDMFIDAFLRKNVMIDFFTAVETNVGSWENNNAETSFKIRYQSSKYGGHECKLRCPPNLCKTQVLKDILNRMKEANGKDAKRPRIVYVGDGHNDACPALQVLNENDVLLAREGKRCPNPNSVYGPQFDKNHDNATSGTFAILSTLEKAERREGCVPKCRVCPWNTGKELLSLVLGILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJ42</accession>
    <name>A0AAD9DJ42_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cyclin C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001548</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJ42"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02984">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01332">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin C-terminal" evidence="2">
        <location>
            <begin position="222"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="356" mass="39426" checksum="ADA5896C2D61D2E9" modified="2024-05-29" version="1">MAAKRRLVDDLLRGENHQILNRSSRGRPEACLHPVWREKVIRWYFSIVSALDRQHHSPDGPFNRSSVHVTTALLDSYLLALPSELALRYKHDRAAYQLLATTCLLIGMRLTQHDQQRKSQVPSENENSDGNDHPTCQLKRAKTHRDHMDQADHQDVDAGAENGSPSHGRPHASCSSTTMVAIPTAATILQMSAAPKTISESKILTMVREVTGSRAFPRSHVITALDYIRVLTSSTQEENSDVKLTQEVAEEAYRLADISLTDVSLIGCRPSVVASAAITLALFRSHHGSRDMVSLRQDVCATIVGEDPAFQVAVRKVEAKLLAAAHQATHAHAPRQMQMNPPIMHRATAHLIPLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DKH1</accession>
    <name>A0AAD9DKH1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_001039</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the cytochrome b5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DKH1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000002">
        <property type="entry name" value="Cytochrome b5 type B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050668">
        <property type="entry name" value="Cytochrome_b5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19359">
        <property type="entry name" value="CYTOCHROME B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19359:SF14">
        <property type="entry name" value="CYTOCHROME B5 A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 8" id="KW-0408">Iron</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="9">
        <location>
            <begin position="4"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1749100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="135" mass="14546" checksum="D4B5744D73FCE52A" modified="2024-05-29" version="1">MAAEKEFTAADVAKHNTAEDCWLIIGNENTGGAKVYDVTSYLDDHPGGAEVMLDVGGKDADEFFEDIGHSNDAREELAKHVVGVLKLTEEEKEKRRLAAEKKSGADSGGMSMIAVLVAAAGIGYYFYKQKVDSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1GY20</accession>
    <name>A0A8K1GY20_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 8">Small ribosomal subunit protein uS17c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">rps17</name>
        <name evidence="10" type="ORF">QTG54_017143</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="11"/>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2021" name="Front. Plant Sci." volume="0" first="0" last="0">
            <title>Chloroplast Genomes for Five Skeletonema Species: Comparative and Phylogenetic Analysis.</title>
            <authorList>
                <person name="Liu S."/>
                <person name="Xu Q."/>
                <person name="Liu K."/>
                <person name="Zhao Y."/>
                <person name="Chen N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CNS00100</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Plastid</location>
            <location evidence="8">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 9">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MW679506">
        <property type="protein sequence ID" value="UAM91351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_010200856.1">
        <property type="nucleotide sequence ID" value="NC_058701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1GY20"/>
    <dbReference type="GeneID" id="68637975"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00364">
        <property type="entry name" value="Ribosomal_uS17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01345_B">
        <property type="entry name" value="Ribosomal_uS17_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_uS17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019984">
        <property type="entry name" value="Ribosomal_uS17_bact/chlr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019979">
        <property type="entry name" value="Ribosomal_uS17_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004123">
        <property type="entry name" value="PRK05610.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03635">
        <property type="entry name" value="uS17_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S11 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US17M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00973">
        <property type="entry name" value="RIBOSOMALS17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00056">
        <property type="entry name" value="RIBOSOMAL_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="11" id="KW-0934">Plastid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1732100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UAM91351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="84" mass="9577" checksum="D145555EFAF9A80B" modified="2022-08-03" version="1">MPVKEKVGIVVSNKMQKTVVVKVESRFPHPIYSKTMIKTSKYLAHDEMSECNIGDQVLVQECRPLSKKKRWSVTKIISKSSVIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRP6</accession>
    <name>A0AAD8XRP6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Gamma-glutamylcyclotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_016876</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000066">
        <property type="protein sequence ID" value="KAK1732482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRP6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35748">
        <property type="entry name" value="OS05G0358400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35748:SF1">
        <property type="entry name" value="OS05G0358400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1732482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="294" mass="33167" checksum="90B74FDA9FBCC0AD" modified="2024-05-29" version="1">MKINIIASLLSSVAVIVTGFSSHTLPTIGLKRKTTPIIRMATADADEAGDDHITILGFGSLLSEKSSRTTFPTLKNFRLGRVLDHRRTFAHPASIFFQRNIANLETLEISSLSVEYKEGCSMVCSVFEVPNEGLSAADAPGDTFIPSQKFLEREEEFEITRVRYEELATSSTSGKQEIKEGVICRRSTDEAYIARWGQERFQKNYLDYGIKTIWGWTEGIRPCPVYLRHCILAAWSCDSEENWSKDGIGGICYNSFLDETVMVDRATSIREYIDQYPEVMNTEPPDNLKERYSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTK2</accession>
    <name>A0AAD8XTK2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015872</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000049">
        <property type="protein sequence ID" value="KAK1733457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTK2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="163" mass="17683" checksum="EAD7625F13A1E586" modified="2024-05-29" version="1">MKMMNLQTVDAIKKGGYKFTLFGDDTSACADDQGNYYSWIRYEASSAEECGESCSNCPGNGKKKDLVLRGFEYVRQYGTCYCLVDSDISFPLTFCSDEGALQALSGVIGGQSGSGEIMNTASLNGSDQCWKVSSKGSKATKTKSSKQPIRRKLGQKNSSHKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUS8</accession>
    <name>A0AAD8XUS8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helicase-associated domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015424</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUS8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.530">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005114">
        <property type="entry name" value="Helicase_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33418">
        <property type="entry name" value="HELICASE-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33418:SF1">
        <property type="entry name" value="HELICASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03457">
        <property type="entry name" value="HA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase-associated" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase-associated" evidence="1">
        <location>
            <begin position="76"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase-associated" evidence="1">
        <location>
            <begin position="148"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase-associated" evidence="1">
        <location>
            <begin position="219"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="472" mass="55586" checksum="DACB00FEC5C89719" modified="2024-05-29" version="1" fragment="single">WEERLAQLKAFKEEHNHANVPYKYPTNPQLGNWVTEQRTHYRLKKEGKQSSMKNERIRELEAIGFVWVLQAKGPQVKWEERLAQLKAFKEEHNHANVPYKYPTNPQLGSWVVEQRTHYRLRREGKQSSMKNERIRELEAIGFVWNIYDDIWDQMMAELAGYVERAGGINKIHHRDDLFGNWFTRQRALKRLRKRGKTCSLTDERIAQLDKYGFHWDVREKAWSDMFKDLEEYKEKHGTTKVKIEDNPVLYRWCTRQRQLNALVDESGISMLKPERKQRLDGIKFDFYRRKGSQRESKIEWKMMHEIVGILEDLGLEWDSLDQVFGSLKFRPDGVIIVPIDSFVIFVEIDEKSHNPTSKSYRVPMEKGREESLKKEANRMGMEHVAFIRVNTGNLFEVSPKQLVTIGKVLQEIRSEKPAGCSIHYVDYDADHVHVQASIESMKSILGFVDDVKINQSEYFNGKAAKLTSKDIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVS3</accession>
    <name>A0AAD8XVS3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Chlorophyll a/b binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014912</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVS3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="204" mass="21128" checksum="D31065E635BF5E97" modified="2024-05-29" version="1" fragment="single">DLLVNHKSENSKHGSTAVVQLNGTLLKLGLFIKVIPAEVNVSVTEVTNVLVSSSRNITHEGNLQPSNEGDDLALSLEGDGIRSDQGGNSVGEGVEGISGVVDVSGEVDSGTGHNLAKEGKLSDTSVLDLNITETVETFLGNVSGEQAEGIEESKRRLDTELILEGVQGGGGGLVLGRGESGGRADKGSDDGRLHDGCCYDFMRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWT1</accession>
    <name>A0AAD8XWT1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AP2/ERF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014634</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWT1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="551"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="93"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="551"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="589"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="636"/>
            <end position="646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="842" mass="91380" checksum="6EC3DDFEC56CAA5D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXG8</accession>
    <name>A0AAD8XXG8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013832</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXG8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041929709" evidence="2">
        <location>
            <begin position="19"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="219" mass="24083" checksum="0A94EE851B8C906B" modified="2024-05-29" version="1">MMKTVLVAGIIALPISSAFVSPHSRYGQRFHVAINDCVAASEHIFSTCSTKLNLLGNLFGNDVADVETKELARFSNLLVSSDVNIDVKFDSLSIMISSWSKMFSDHKKMGLTTAVDVVELPKSGDSAGVQLLFKKGKGGRFAYRDKDDKNDDGDKKKQKEDSVKEGGVQVMINKLSDGNLEVIASRCEIEEGTIIKEMSEQTIIDSLGQTMKAWKKEQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXT3</accession>
    <name>A0AAD8XXT3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">cGMP-dependent protein kinase</fullName>
            <ecNumber evidence="4">2.7.11.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">QTG54_013795</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.12"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.12" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXT3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030553">
        <property type="term" value="F:cGMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004692">
        <property type="term" value="F:cGMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000068">
        <property type="entry name" value="cGMP-dependent protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002374">
        <property type="entry name" value="cGMP_dep_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF143">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000559">
        <property type="entry name" value="cGMP-dep_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00103">
        <property type="entry name" value="CAMPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 17 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0140">cGMP</keyword>
    <keyword evidence="12" id="KW-0142">cGMP-binding</keyword>
    <keyword evidence="10 23" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 17 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7 23" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="21">
        <location>
            <begin position="103"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="21">
        <location>
            <begin position="221"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="21">
        <location>
            <begin position="347"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="20">
        <location>
            <begin position="474"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="22">
        <location>
            <begin position="735"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="772"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="774"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="16">
        <location>
            <position position="599"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <begin position="480"/>
            <end position="488"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17 18">
        <location>
            <position position="503"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000559-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR000559-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAK1735632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="792" mass="87867" checksum="94ACA10FC0823279" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XY59</accession>
    <name>A0AAD8XY59_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Amino acid/polyamine permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_013505</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the amino acid-polyamine-organocation (APC) superfamily. Polyamine:cation symporter (PHS) (TC 2.A.3.12) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XY59"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015203">
        <property type="term" value="F:polyamine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044566">
        <property type="entry name" value="RMV1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45826:SF2">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45826">
        <property type="entry name" value="POLYAMINE TRANSPORTER PUT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="375"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="425"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="472"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="513"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="569"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="595"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="626"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="651"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1735799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="726" mass="80231" checksum="BFE11780F42E6965" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYK2</accession>
    <name>A0AAD8XYK2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_012851</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000041">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase ERECTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000400">
        <property type="entry name" value="Nuclear pore complex protein NUP107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013210">
        <property type="entry name" value="LRR_N_plant-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052941">
        <property type="entry name" value="StomDev_PlantInt_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48004">
        <property type="entry name" value="OS01G0149700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48004:SF99">
        <property type="entry name" value="OS09G0491612 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08263">
        <property type="entry name" value="LRRNT_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1183"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1261"/>
            <end position="1282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1317"/>
            <end position="1335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1355"/>
            <end position="1377"/>
        </location>
    </feature>
    <feature type="domain" description="Leucine-rich repeat-containing N-terminal plant-type" evidence="9">
        <location>
            <begin position="645"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="domain" description="Leucine-rich repeat-containing N-terminal plant-type" evidence="9">
        <location>
            <begin position="1013"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="169"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="224"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="375"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="98"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1419"/>
            <end position="1460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="235"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="381"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="398"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1736251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1472" mass="163639" checksum="114EF754582463CD" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZ93</accession>
    <name>A0AAD8XZ93_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SOUL heme-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012954</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HEBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZ93"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="entry name" value="Regulatory factor, effector binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006917">
        <property type="entry name" value="SOUL_heme-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11220">
        <property type="entry name" value="HEME-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11220:SF58">
        <property type="entry name" value="SOUL HEME-BINDING FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04832">
        <property type="entry name" value="SOUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="Probable bacterial effector-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="171" mass="18950" checksum="819862B7EDBA23AE" modified="2024-05-29" version="1">MGSVFGKESVEEPPHDTLLSRSDATTSYELRKYGQRYAATITYKKTGDKSENSPFGALAKYIGVFGTPQNEGDTSIAMTAPVVMENSNKPTQIAMTAPVVMENNKDDDSDSNKKMMFMLPVEYDSMDKIPKPTNPSVHIEEIPSQTGVVHVYNGKWGEARNTELAKVWHNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZJ5</accession>
    <name>A0AAD8XZJ5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZJ5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="228" mass="24651" checksum="0FE3FB7B0E153A4D" modified="2024-05-29" version="1">MSTVPKYVYCFPFFSALIALILCFAGTSCKFLSISTTDATTPFSLDFGLWYHQTVNVTSNGIIASSTCSLYPPDQQVDSAWVAARVFNLIAIILGATVIIFDGCSGCITTNPKKRLQGGALVYLIVAFCSGMSLILLNTNICSSNRNSTVAALNNMDFSSCVLSTGGKSAIASCVFWVVAAVLSALLHPSSRLRRARDDNGLDEPLVQEYEYEKEAFIDENETDTETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y216</accession>
    <name>A0AAD8Y216_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011687</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y216"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042105660" description="RING-type domain-containing protein" evidence="1">
        <location>
            <begin position="30"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="236" mass="26499" checksum="7C33FE9DFEC562B1" modified="2024-05-29" version="1">MGANLSQFVWCVSTSIALVFAAILLSAEGSNGNGSNDNDNDNDHSNSIKVYASCGIVVDEDGKKCDACEFACKHKKRASEGFLFKQPNKSTHLEDCSICCLPFSYDLKESSIMPCCCEWICIGCEASDMIREKQERLEHKCPFCRHPAVQSSEVYRQCIMNRIEVKDPVAMQIMGTTCYHQGHYDSAANYLTRAAELDNAEAHYQLSNFTVLRSLEIIFFLRKRFTKGLVRIDSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y338</accession>
    <name>A0AAD8Y338_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010789</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y338"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="480" mass="54503" checksum="581BDF7361EBA126" modified="2024-05-29" version="1">MEEGSGSNGAREPQEARLQSPDSQMKRPQHSPPQHDATAGEQTKRRRTDLNITDLPDEGLRLIADYLPKTSRALLALAITTDSASWRDINWNKSIAPTLTSFLRREKQQRPLAATRAVLLKSSAGGDDNERFWEHVDFVDIGDLASRLNDDDVAGFLMCINAIQKLKTLKLTGVVNITGRGLDPLRGSRILEQLDLSLVGLDESPDLSPQPLIKDTVVVPILDSILIDQSDHNMKHLQFPRKWKRSGLLDQFILRYDQTEYRRNMCCLQCRRRCKDVLSPSRSDFSCRIEQNTCYGCLKHYCYDCLDEDPNFDAEEWGPMLTFCNVCEKEYCARCSGNDSDGMRGMFECTGRPCGRDCHKCVCDHCYEKGTGKCMECGNAFCKDCQEDDFMSCEGCGDRACYMCMQLDTCEFEGCDAENCHRCVDDKVNAVSFCFESDCQNSYCFQHRLEQCNKDWNTCCEGCMRLIGPELKRGYVPRVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y384</accession>
    <name>A0AAD8Y384_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fibrous sheath-interacting protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011033</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y384"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041961373" description="Fibrous sheath-interacting protein 1" evidence="2">
        <location>
            <begin position="25"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="271"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="321"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="413" mass="44812" checksum="67B761ED8205C8F3" modified="2024-05-29" version="1">MKTATHLLCTVAVVVTSSHHRCSAYVTAPSSFGIKSYATRAIRGKKGYSTIGTSRASTCMYSVPYLPSMEEEGDDGSFFLSASQQAANERYELLKQGKDPLAISLSIAPAQEESQEQEQDTAEKEEVTAAVNESDSIDDNTGVESLPTLQTDDYDNLLSSLSESPLAQSLEEEEEEDTTAATELEEGSSASSTLDEIKRVEDEITAVKSQIKYKFQKRLMDTRMQFDDAERVGEGNTAEEMEAARNARLAAADQVKQVLVSGEELEEEEAAVSVPTSTDSTSTVDAGEGSTAEEMEEARKARLAEADEIAKTLKNIEPTAVTAPTTSTVQVEEEVEEETIEPVVETSPAASKIEEEPSNANQSKLSSDGKVIYEPSQAALDINQENVDNGLMVLTRSFLVLNSIVQRLDEDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3B3</accession>
    <name>A0AAD8Y3B3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_010207</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3B3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1738891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="156" mass="17295" checksum="D9B70590F4932D9E" modified="2024-05-29" version="1">MRVEHVECHDLEQALVDDFEAECGKLASSAAAENLRSSLKEAWSRLFDAKGNLLPPQPKQSKRNTTTTKRRVKTEPAIRIFVAGDKSQVGKSSICMGLLGALLKTGKYTPSDLAYIKPATQCEAIQLVEEFCKHKGITSVSQLGQLYITRDSRDHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3D9</accession>
    <name>A0AAD8Y3D9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_011325</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3D9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06174">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049680">
        <property type="entry name" value="FLVCR1-2_SLC49-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10924">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10924:SF6">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 49 MEMBER A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="565"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="599"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="629"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="732"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="376"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="380"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="424"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1738031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="796" mass="87063" checksum="685DCB6B56F444A2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3M5</accession>
    <name>A0AAD8Y3M5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Methyltransferase</fullName>
            <ecNumber evidence="6">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_010269</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3M5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051419">
        <property type="entry name" value="Lys/N-term_MeTrsfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12176:SF80">
        <property type="entry name" value="EEF1A LYSINE METHYLTRANSFERASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12176">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="5">
        <location>
            <begin position="61"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="10"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1738953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="311" mass="34755" checksum="FA5F15A337922E41" modified="2024-05-29" version="1">MKKRQRRIEDEEEEVGDGNEEEDEVAEEHPQDDEECADDAEDGGHDICEMPIVEVITPPDKPKKVLEVGCGDVALGVDLAADLVKMQEDTDIGAELLVDEISCIDYSDIVVKTLIEKQKKEHNGSSSTLQASFHSLDARSLHYAPNTFDLVLEKGTLDAMLSDKDEGKQNCIQIVKEMARVTNIGGSILIVSHLNANESKGMKWLEDVVFSGLKAEFRERREAIKKQQAEFYSWSIHIHGGEGQLIKDEDDEEVMSYGPAVYIIKKKSVPADRAQELFSSKKKDAKNVESENGDETELTLPPVKVEFLTYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3Q1</accession>
    <name>A0AAD8Y3Q1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010895</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3Q1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="138" mass="15430" checksum="6EF77A8F71621C1B" modified="2024-05-29" version="1">MGITDIVAFCSWILKDLRTENILQICSGYVLLIMSILVFYFQMKETIDSTPDRIDLLANWLVYVDAILNVVLRHVELSVKFLDDETNRIELAVVILLLITAVLYVSADVIRIKSSGGGGTQQLQSAQKTPTPTQQTDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3T6</accession>
    <name>A0AAD8Y3T6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dolichol kinase</fullName>
            <ecNumber evidence="3">2.7.1.108</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_010723</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the polyprenol kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.108" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3T6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004168">
        <property type="term" value="F:dolichol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043048">
        <property type="term" value="P:dolichyl monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032974">
        <property type="entry name" value="Polypren_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13205:SF15">
        <property type="entry name" value="DOLICHOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13205">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 15-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="66"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="200"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="275"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="476"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="511"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="550"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1738693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="611" mass="67929" checksum="D91C17E04391687F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4I3</accession>
    <name>A0AAD8Y4I3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010223</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4I3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="182"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="137"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="303" mass="31402" checksum="1379E8E01D5D109F" modified="2024-05-29" version="1">MIESFGGKVTTRFSKNTSFLLAGNNPVAKRFTDARAKSIEIINLVRLNGLLKGQLTFDRLGKLEALDSEEFMGDAYQPATNASVAFGDAKPAAAKKGAKKPAAAKKEAKKPAAAKKEAKKPAAVNPPLESDDDTKPAAAAAATSQALVAHANPSESTSSTAVVPVSGKKTKFQMPRPGQNGAISGIFDGQRFVLTGLFPELGGGGGLNLGKDKMKALIENFGGRVTGSVSGKTNFVVVGKDPGASKVGKATAKSIPLVDLLALNRVIHGQATLDDISSEPAPRITNFSAGYKGNGLLKNTAEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4Y5</accession>
    <name>A0AAD8Y4Y5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4Y5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="228" mass="25945" checksum="D3574F11FAA66F88" modified="2024-05-29" version="1">MAPNANNHLDPSYAFQPKMTHHPTSINRGKPSTPQTQSQRVAPSLVTSRVDDYPPDSADTLKMFNESLQQGDRQGSHLSTMSDVTLEFGCNLNEDWTNVPHQKPFTAKRDETDHLATIINLKMELAEVHAKNDQLALLLRQCMAEKIDIECKMRDSLRSSNMQTQSEPAHNHRHSFHAPPSYQPTKHVHRTNSMEHAPSTHKPRVWHEEVLSTNARQNKIDYVGKLMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y535</accession>
    <name>A0AAD8Y535_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NXPE C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010277</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y535"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057106">
        <property type="entry name" value="NXPE4_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24536">
        <property type="entry name" value="NXPE4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042256451" description="NXPE C-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="NXPE C-terminal" evidence="2">
        <location>
            <begin position="69"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="341" mass="37944" checksum="47158F88C6E7B791" modified="2024-05-29" version="1">MAPLILLCVCSLFSFAIIIHQYHALGSLRVKNAQHTGEEAMSTTTATTAICNNLNMLTSGSWNNVTKQWHPFNCSFTPFDKPRVDNCLSNKQIGFYGDSTLRNIAHELINLDKANITLAGWASSAKRYICGAGQIGSNGSSLAMYWTPSAFYQKPASMKSIETDDVSIISISVWDMGTYYRGVNPWFVAMKKIILEAAKKRRNKPLYVMNLHNIYASKCTLKNDNDQGRKALKLCQECNKMDAMFAFRDAIASAVRCVKEDGYHNVYLIDTFGVTNSSFGEEHSDGVHFSSEVTQVELQVLLSAICNSSFQHDLNETLLSSGTCPSQPNFEEGRQLGCKQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5M7</accession>
    <name>A0AAD8Y5M7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DUF2786 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_009116</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="protein sequence ID" value="KAK1740166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP001224775">
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="DUF2786"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DUF7168"/>
        <property type="match status" value="1"/>
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            <begin position="440"/>
            <end position="479"/>
        </location>
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            <begin position="526"/>
            <end position="657"/>
        </location>
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            <end position="23"/>
        </location>
    </feature>
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            <end position="210"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="392"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="408"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="634"/>
            <end position="679"/>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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            <end position="12"/>
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    </feature>
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            <end position="204"/>
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            <end position="344"/>
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            <end position="373"/>
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            <end position="392"/>
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            <end position="645"/>
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    </feature>
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        </source>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="751" mass="84846" checksum="7D8EBF6377E99F3B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
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        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
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                <person name="Vandepoele K."/>
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                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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        <source>
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    </evidence>
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        <source>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y707</accession>
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            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
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    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y707"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
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            <end position="480"/>
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            <end position="808"/>
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            <end position="935"/>
        </location>
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            <end position="14"/>
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    <feature type="compositionally biased region" description="Basic residues" evidence="1">
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    </feature>
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        </location>
    </feature>
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        <location>
            <begin position="915"/>
            <end position="924"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1073" mass="118310" checksum="9125532783604335" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y708</accession>
    <name>A0AAD8Y708_9STRA</name>
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        <submittedName>
            <fullName evidence="2">Transcription initiation factor TFIIE subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009225</name>
    </gene>
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                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        <property type="protein sequence ID" value="KAK1740275.1"/>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAK1740275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="355" mass="39584" checksum="EAD6AEBD699B0C6F" modified="2024-05-29" version="1">MVDTNSGRFLCRECVRAYTNHPNAPPVEEYTLQLVDNQVELKSAMDNLRRVNVQFSSKMESGGGGGGGEGSSNNQQQQRPLRQGIFELLQKVRPIRGAEPITSNLPSENISMGVGSKRLVGTGRTAKNRNTKLVKQGIPIHGRRGGSNYYDTDELTFLKNAMGQEIAFELERGGGARANLLCTKGKIRNKLVDAAARKTGVDLGLVARVILEERERLKRKREEKEKEDENGGGGKKKKKAGVQEFEFLQDNLGENGWDGGQLTKEEKENRRLAYLGGDDDSSDDEDFEKKMATNILTDETDELRNLPENDFKAAFQQQYKMEVERQINLLGLKSLDDLMPSLEDDEDGGVDWEDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
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                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
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        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
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        <source>
            <dbReference type="EMBL" id="KAK1740828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="227" mass="25916" checksum="6B15C5790D0A7C42" modified="2024-05-29" version="1">MGIIHIPRTIAAALRGAIKRRLSPLSDQEISLVGTKDVPHIYSSRAGLFDVDLMGHMNNASYLQHAELARWEWSSFGGSLAQSFKTKSFFIVTASMIRYRREIVPFKRFDVETRLVGLDDRNLWVYQTFHHHVNRENKQEESDGPTRGKILAQILTQAVMAKPEKGVINPRAWLEDNSIYSSSVLDGIMNEKGENIESIFDEKAKRFTHLEDILKRSAANYDDKVPK</sequence>
</entry>
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    <accession>A0AAD8Y7P0</accession>
    <name>A0AAD8Y7P0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008783</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
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        <lineage>
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            <taxon>Skeletonemataceae</taxon>
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    <reference evidence="3" key="1">
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                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
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    <proteinExistence type="predicted"/>
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            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042110650" evidence="2">
        <location>
            <begin position="20"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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        </location>
    </feature>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
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        </location>
    </feature>
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        <location>
            <begin position="732"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="785" mass="88545" checksum="FCDFB5A0342D5E35" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7Q1</accession>
    <name>A0AAD8Y7Q1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_009115</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7Q1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="204"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="252"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="40"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1740165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="415" mass="46133" checksum="18984CC191DE6A4A" modified="2024-05-29" version="1">MKLLSKLLKKKKKNNLLPPSSTTPKRNKKSQDPQTPPISPSRQFVTTTNNGQHIDDDDISAVTPATALPESPNSIAGRKRYNNNPVENKPAVSLLLGGNNDDDSSSHDFMVFEDKTEDNSSYGSSSYQRLAATGFGGGKSSAPFPGGKLKVSFSDDAANNYRMKMKNDTATATTTPTTSAIKKKSGAVKNLVKKRSSILTKTSYFTKIVNSAFDKVDVDKSGGVTLEELYSGLLLIHLQMAIYVGAPACRPASKKYVSEVFHIVDTDNSGTLDRNEFKIVMQILYSQVFTRIVIQWTLTLMLVPVTTKYILQYTTLFLLAMHEFWKDVDDDLDPVQRLLWKLWESWLFYSPDALDQVGALCWLVLCKIPFKSMPPVMLTVAQTSVALPWALNHVEDFFRRAAHSLVSDEVISSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8A2</accession>
    <name>A0AAD8Y8A2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8A2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="451"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="505" mass="56925" checksum="46CE1E8B9569C257" modified="2024-05-29" version="1">MADVEISGDGSGNSKRRRLSDGAARLHNDDDSPPNCLADLPSGILAHTASFLAAPSRVLLLHALNDSDDDVPSSSSAIVGSHHEVLDFGQIEKDLAEKLSDQDIQRILLHTDAVNKVKKLLLTNCIKMTGVGLEPLRGSEIIEQIDLSIVEFVGDDRETSISCDHVLPILDSLIEREGPAMKHLQFPKKWRKEVVTESDFHAFLGRYNQMWEGRGRIDCPMCKEQSVLAYDGEEQDIIGPWVYTSEHSEEWNFYGTHNNVCYGCLKYSCGECDDGGSLLHFCYKCERTYCVHCATLNYCSVCEKEYCLDYCKEFYSCDGRPDADFGDYDFKCGQNICEDCVYSERRECRKCKKSYCSTDCSNRTYDEDEINRCDHCCSFLCYDCDNPLSSSNTLAVADFFNKVLSGRHDIDKLRKCGDCNKAACADCQLKFGKSVENLDCKGCVKMIVSALLEEKEMKKELQGELERKNERLESNSAQIEELKEENCRLKNGIKEVKNAIKGLPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8D9</accession>
    <name>A0AAD8Y8D9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008157</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8D9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="171" mass="19600" checksum="4FD2D9C33E9839B1" modified="2024-05-29" version="1">MSDNILFRQPESSHLGDCPICILPLPLDTKKSMMQSCCTKRICIGCYCAGIKFEMGEKLGKRKRICPFCRQPEPKEDVEIEGYKTRRMEVNDPVAIREAGKRCYHQGDYESAFEYFSKAADQVMRKHIIACHLCTETGTVLAGKWQRDYTIWKRLLLAVIPKLDTILGCTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8H1</accession>
    <name>A0AAD8Y8H1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008139</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8H1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAP" evidence="2">
        <location>
            <begin position="42"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="149" mass="17459" checksum="54C859320791BC3C" modified="2024-05-29" version="1">MYASFNKREPRQDAPLEHHSPPVTQAEPQEEAVNNDWTEASLKALKNDELKAILQGLGLKRSGNKKELVDRILGREVVTENKKKPKWRNSKARAMLVRMLMDKQSNVHKMTWKEIHASHEWFQEYDPMLFQRYVRDLRKANPQKVAVGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8K2</accession>
    <name>A0AAD8Y8K2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipase class 3 family protein</fullName>
            <ecNumber evidence="2">3.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007374</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8K2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051218">
        <property type="entry name" value="Sec_MonoDiacylglyc_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856:SF11">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="1">
        <location>
            <begin position="128"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="380" mass="42923" checksum="FA322B3E6C95CFA0" modified="2024-05-29" version="1">MLWASKLVYSFAKLLQEGRAGGLDLADTFPPEVLAAYKDERLDVRDLGEGNGLSFNAVLKIVVANAENLKKIEPEFEYVAKMIEKIQAVENADESSDELFLETFSSIDAATQCVYGVLKDTKNKRVTVVFRGSTDFSTRDWQTNLSAQLEGIKTPKLLKDSLKGKLKKRVLVHRGFYEYIFDNKRAKGDQRYDMILNDIKPFVEEGYKIYVTGHSLGAALASLLAFKLAGSDKSWIPKPVTCISYASPFVGTDGFRTAFTLLEQMGHIRYLRVNNDADTVPTIPPFSLGWKKRLYKHVGINLRLYDDSFILSHPNSNGWGFVNAVRNSVLKPVWSVLTYHSLQTHEDRMDAQKERLQHMNLDDLYANEELFGKPKTSLCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8K8</accession>
    <name>A0AAD8Y8K8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8K8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="220" mass="23256" checksum="EA431F359941C879" modified="2024-05-29" version="1">MAAPGNTFTTTTTNNSMEEDTLLLAAEAAAALIDNANSSTTSNNNTDLLTQVELAAAAMGGGQSLQKGGFDNDGLLLMGQREHDADQAMMTAFENEFGGGATTNDDNINNDTATIANSNRNKQSNFLTFSSRVPQNQPLSMEHTNFLSYYYSNESAGHNATMRGNGKKKNDDDEIVVEEGEDEGGGKKGGGASSAKTAANEEGEQHRQRQHSTKGYGGDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8L8</accession>
    <name>A0AAD8Y8L8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nudix hydrolase</fullName>
            <ecNumber evidence="2">3.6.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8L8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03676">
        <property type="entry name" value="NUDIX_Tnr3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="192"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="380" mass="43258" checksum="B96BB774C8350192" modified="2024-05-29" version="1">MAACCVLRLNNSFLLRTTSSAAIGRRMMSSSTASANNPPTLLQRIQALDKSSLAPSYTALVLFYPSPSSQYAVVGHVQNSLMKSTLINCKNDQGEPIFVLEEKRSNQLGTVKDILRLNVDVQYERNNTNDDAYEPAELFQRRTESFAQVTKKVVSRQHSDIYPVYPFVERMDPLYDDNVILAHVNRSTAAYLGIDSVGVHLNCYVRQNNVIQGVWLAKRASTKSHHPNYWDTTVAGGQPHNLSLYDNIVKEAHEEAGVPSEWLRNDASNKAFSDHTHDPLTITTAKEDGSCMKRSFYYSFDLQVPDEWQPTPVDGEVQEFKLYSIEELDRELRFGQSLRPAMRAVLLDFMMRHGLFKDVEGEVDRSELSKAMRRERIRLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y934</accession>
    <name>A0AAD8Y934_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helicase-associated domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007647</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y934"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.530">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005114">
        <property type="entry name" value="Helicase_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33418">
        <property type="entry name" value="HELICASE-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33418:SF1">
        <property type="entry name" value="HELICASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03457">
        <property type="entry name" value="HA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase-associated" evidence="2">
        <location>
            <begin position="10"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase-associated" evidence="2">
        <location>
            <begin position="86"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="189" mass="22066" checksum="B8CD2850E7336C41" modified="2024-05-29" version="1">MVQSSQEDPGWEEQFFALKAYQRETGHCKVPARFKSNPKLGRWVMTQRRQFTLLMQGYPSALTAERIQRLESIAFTWSIRPEPVKTWNRKFQELKVYKNTFGNCMVPQRYQANPQLGTWVHTQRRQYKLMIEGKKSSMTREKAQALDSIGFFWAAKPSSASRSNNNAHHTQHARIGQEMNNSIGLVEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y968</accession>
    <name>A0AAD8Y968_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Hemolysin-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_007755</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y968"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1280.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22777">
        <property type="entry name" value="HEMOLYSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22777:SF17">
        <property type="entry name" value="UPF0053 PROTEIN SLL0260"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0129">CBS domain</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="302"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="336"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="374"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="13">
        <location>
            <begin position="230"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="448"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="581"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="514"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="815"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="125"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="159"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1741277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="850" mass="93545" checksum="808ECF54DB363966" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9G0</accession>
    <name>A0AAD8Y9G0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008463</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9G0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43689:SF8">
        <property type="entry name" value="ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43689">
        <property type="entry name" value="HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="119"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="403" mass="43395" checksum="993C9C748EE5F54F" modified="2024-05-29" version="1">MKTSTMMRSNYAMALAAILASPQTAHSFTLTLPKSSSSLTTSLSATSSSYQEDLTFTPPNTLIEGSISEELCTAAAQKMKRVMVPISTDISETGFVGISFIHFEAQKSSSSSNKKTLPLLLVHGFDSSALEYRRLGPQLAAMGVDVYAVDLLGWGYTQLENVKSFSAAAKVEALQGFWNTVGGSGEVVVGGASLGGAATIEFAAKNLYKQEGAVNSDNNSTEGFVRGTVLIDAQGFVDGIGPMSFLPAPLARAGIKVLQSVPLRNSANQMSYYNPETYATEDALKVGRLHCLRDGWEDGMLSFMQSGGFRPKEKVSQIDVPSLVLWGRQDGILEGKEFAQKFIDAMPNAELQWVEECGHVPHLEQPELTARYIADFLESDKMTPLGKSASVNPLFGNLLSFLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9V8</accession>
    <name>A0AAD8Y9V8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pentapeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_007914</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9V8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044213">
        <property type="entry name" value="At2g44920-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47200">
        <property type="entry name" value="THYLAKOID LUMENAL 15 KDA PROTEIN 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47200:SF2">
        <property type="entry name" value="THYLAKOID LUMENAL 15 KDA PROTEIN 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1741436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="265" mass="28496" checksum="821726E96D677430" modified="2024-05-29" version="1">MTTNDDWIMLIITIELFNTTTVVFKMVSFRTTFIAAAACGGAAAFSPSGLPSLNSRSTQVELHATSSIQDRFSAAATTLLSFTLLTTPLVTTPQSAFAEDPSQGASLAANSKITTGGASTLQSGRTIAITRGVNLDRSDFKGQNLKGVAFQQSIVRDSDFRGANLVGASFFDATIDGSNFEDADMSLCNLEMAQLNRANLHNTVMREMYVSGSTLFEGVKDIEGSDWSETQLRKDQKKYLCEHPTAKGTNPVTGVDTRESLMCLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YB07</accession>
    <name>A0AAD8YB07_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipase class 3 family protein</fullName>
            <ecNumber evidence="2">3.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007343</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YB07"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051218">
        <property type="entry name" value="Sec_MonoDiacylglyc_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856:SF11">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="1">
        <location>
            <begin position="129"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="382" mass="43253" checksum="A72152C98D648CA0" modified="2024-05-29" version="1">MPMLWASKLVYSFAKLLEAGREGSLDLGDTFPPEVLAAYKDKRLDVRDMEGGNGLPYNKVVEIVVANAENLKEIESEWEYVGNIIQKIQAAEDADKSSDDFFLETFSSIDAATQCVYGVLKDNKNKRVVVVFRGSTDLSTRDWQTNLSAQLEGMKTPKLLKDSLKGKLKKRVLVHRGFYNYIFNNKRAKGDQRYDMILNDIKPFVEQGYKIYVTGHSLGAALSSLLAFKLAGSDKSWIPKPVTCISYASPMVGTDGFRTAFTLLEQMGHIRYLRVNNDADTVPTIPPFSLGLKRRLMKHVGINLRLYDDSFILSHPNSNGWGFVNAVRNSVLKPVWSVLKYHSLQTHEERMNAQKETLQNLHLNDLYDDGKLLGKEFNRDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBG4</accession>
    <name>A0AAD8YBG4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA (cytosine-5-)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_006669</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1743072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBG4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044027">
        <property type="term" value="P:negative regulation of gene expression via chromosomal CpG island methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.120.10">
        <property type="entry name" value="DNA Methylase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050390">
        <property type="entry name" value="C5-Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056866">
        <property type="entry name" value="Znf_WRKY19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10629">
        <property type="entry name" value="CYTOSINE-SPECIFIC METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10629:SF52">
        <property type="entry name" value="DNA (CYTOSINE-5)-METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24906">
        <property type="entry name" value="Zf_WRKY19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 5 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="8">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="237"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="296"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="407"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="249"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="278"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF24906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1743072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="951" mass="105695" checksum="641D8A0FC8D68D39" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBZ8</accession>
    <name>A0AAD8YBZ8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ankyrin repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006356</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBZ8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052420">
        <property type="entry name" value="Espin/Espin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153">
        <property type="entry name" value="ESPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153:SF8">
        <property type="entry name" value="FORKED, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="246" mass="27199" checksum="5EC9E0C78D8C39EE" modified="2024-05-29" version="1">MHFSFPHIKRSKLPLYLFEEDWAAALAEIECHPREARHWEFRAGFFDGEHESSVLPLHVACSLHTPLHVVRAIVEAYPEAMRMNESAFKRLPIHVACQFAERPEVIKYLVEEDRSTALEPDVLGRLPIHYACSNGSDPTVIKTLLAANPASALYADYNGWLPIHVAINFGASTKVIEELVKACPASVAVQTMKGSTTVSLAEKVSTKNKADILKVLKDAVASGKCEGRHTSKFGKTSHVMQISRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD40</accession>
    <name>A0AAD8YD40_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">N-terminal acetyltransferase A, auxiliary subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_005539</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD40"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.1040:FF:000003">
        <property type="entry name" value="N-terminal acetyltransferase A, auxiliary subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1010">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021183">
        <property type="entry name" value="NatA_aux_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767:SF2">
        <property type="entry name" value="N(ALPHA)-ACETYLTRANSFERASE 15_16, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767">
        <property type="entry name" value="N-TERMINAL ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12569">
        <property type="entry name" value="NatA_aux_su"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000422">
        <property type="entry name" value="N-terminal-AcTrfase-A_aux_su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="103"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="661"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="678"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="691"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1743942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="920" mass="103226" checksum="8EC31DDA8094861F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDZ5</accession>
    <name>A0AAD8YDZ5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA2/NAM7 family helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005066</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDZ5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20336">
        <property type="entry name" value="Rcat_RBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF495">
        <property type="entry name" value="HELICASE SENATAXIN ISOFORM X1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="1">
        <location>
            <begin position="453"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="2">
        <location>
            <begin position="869"/>
            <end position="1031"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1058" mass="119104" checksum="84DA0B53AA11944A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEB1</accession>
    <name>A0AAD8YEB1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">STI1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004034</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEB1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042082280" description="STI1 domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="389"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="419" mass="46536" checksum="91B7DD48623C200C" modified="2024-05-29" version="1">MKFSYLSSILFVPLASAFAPSSSGITQYNAGVAQRQCELFSTPSPEDIRRLMEEESSDPKTLADSAERMKNMTPEDMATLIAEMENMDPVQKAQLKGMGMDPDTMLISMKMMKDNPAMMATAQKLMSNMTPEEMMKQSKEAQEKMSSMSKEELEAAAEVAKKQMEQISPDMIDEAVKAMKEVSAADAYTSSDPNVVDAMYAVGEMMSKPPTGKVTFQAFSVLPPIVALRGDRDQDLSKSELEECWEEGSLGATRVDRAGFKRVWDEVQEYFEEDIMEESRLTIHAKVAKKRSSVTPEVQATAAAPVVGQSLGEDEMKFVNEQVKSMSDDDMIAMLEGMGNIGPEEEARMKAMGADPAMMRKAADMMKSNPMMRKAAAMMMKNMSPEQMMQASQQAQSQMKNMSKEDMEKAFEEMNKNAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YF57</accession>
    <name>A0AAD8YF57_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cold shock protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_004014</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YF57"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012156">
        <property type="entry name" value="Cold_shock_CspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050181">
        <property type="entry name" value="Cold_shock_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019844">
        <property type="entry name" value="CSD_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11544">
        <property type="entry name" value="COLD SHOCK DOMAIN CONTAINING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002599">
        <property type="entry name" value="Cold_shock_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00050">
        <property type="entry name" value="COLDSHOCK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00352">
        <property type="entry name" value="CSD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSD" evidence="3">
        <location>
            <begin position="2"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1744723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="81" mass="8946" checksum="ED7643357C8796D9" modified="2024-05-29" version="1">MSLNGTVKFFSDKGFGFITPEDGSEDVFVHFSAIVKDGYKSLNDGETVTFEKVFDDVKQKYSAANVVGNGDGTPRRHTNYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFB2</accession>
    <name>A0AAD8YFB2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFB2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="147" mass="16837" checksum="8F230716E92C30D1" modified="2024-05-29" version="1">MNNIDNDDPISATGIQRRQFLIASATLLQLSLATAPANAREPKLTERTNFQQSPINKRFGITLSEPERIYNLSFITYLSRFLLVFDKECQQWWYTQAQAIPPNSSKEEVDRIRFEQFGKFSASVEVGLMDYEGRDGGDGVKSLLMHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGJ9</accession>
    <name>A0AAD8YGJ9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004333</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGJ9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1745042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="306" mass="35115" checksum="CA6B6BE36C4AD9B2" modified="2024-05-29" version="1" fragment="single">EKERAYNNNARGTFLSICPRFLSWCCLCNHVLGIQLDRGGGGKEHRVKIIRQKESRNYVEELMYKYKSDKSRDDHSYVKLYNMIFASIRHSVTNITEIGISHGQSIQAWFRYFPNADIHGFDVKWYGEDVVKINLEHLKPRVHTHIVNILENNITMSGLGFLPESMDIIIDDGPHSVSSQEGFLQKIFPCLKPGGYYIIEDIGIAGNGNGVSLFHDDPSKLQQATRDILEAHDTIWVDTAIGHRAWKEWLKRVGGRWARNTTHHNSYMIVIQKRTDPLREPYQMHYKHSAMNLGGVVLENVNANAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGX3</accession>
    <name>A0AAD8YGX3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_002986</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGX3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007203">
        <property type="entry name" value="ORMDL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12665">
        <property type="entry name" value="ORMDL PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04061">
        <property type="entry name" value="ORMDL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="255"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1746379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="291" mass="32521" checksum="4FF670A358D9358D" modified="2024-05-29" version="1">MASSAQASPRQRISSADLDAFDDFNHINNNNNNNGGNRSLLSDATNNNKAHHQHIIIGKSIAPTTNNQKQLQGWIQPLPFELSRNRNTDWIAEGGPSLLLFYLLLILVVLLTFLAFVPEPKLAWTLTNLRMPLGNPADYMDGTQGEMNAMTCWEQIVSKPAIHHLDTRARTYSDASTGSNMDQHYMGLRQRMTVAIKKLRSRDVLCVIPTLLAHASCHVAKYQSEYVLVNVGMPFMNGVRLFGINRTIGIDDGAYETEEDDDDCANDTEEDSTNDESLGLEIINEETKKTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHR1</accession>
    <name>A0AAD8YHR1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_002128</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHR1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="13"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1746784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="189" mass="20811" checksum="D7F976316C9751C0" modified="2024-05-29" version="1">MSEENVVADDSCCASCGVAEVDDIKLTECSACDLVRYCSDACQKEHTSHHQQECKKRAAELRDELLFKRAAELGDVDAQYELACLYEFGKGVEKDRGKAIHHLEEAAIGGHPYARRTLGLIEWDNGNIQRALKHFIIAASLGDDVSIKFLMKAFRSGLVSKDDLASALRAHQAAVDATKSPQREAFEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YI82</accession>
    <name>A0AAD8YI82_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome c oxidase assembly protein Cox11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_002383</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
            <orientation evidence="2">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YI82"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.370.10:FF:000001">
        <property type="entry name" value="COX11 cytochrome c oxidase assembly homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.370.10">
        <property type="entry name" value="Ctag/Cox11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00155">
        <property type="entry name" value="CtaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023471">
        <property type="entry name" value="CtaG/Cox11_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007533">
        <property type="entry name" value="Cyt_c_oxidase_assmbl_CtaG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21320:SF3">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21320">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04442">
        <property type="entry name" value="CtaG_Cox11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110111">
        <property type="entry name" value="Ctag/Cox11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1747039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="329" mass="36179" checksum="B32C5F1E89421B63" modified="2024-05-29" version="1">MNNKHSSSPNNTINFNSTYLRRKFSSTTEQQAEKVTLTESQAAALAQRRAYEFYRIKSGAPKNSKGSSQSNESIDDRNTKLASYAAAAVIGALGATYAAVPLYKIFCQTTGFGGTTQRVNLSEWAENQEAREESGRGKVSQALWDKLIAMSNVPSEMLPGSSPGSSSHGRGARTWTDEEAAAKLASLRPVKDGRLITVRFDSTVGDVLPWSFIPAQLDVKVVPGETALSFFTATNKSDKAITGVATYNVHPPKVGLYFSKIQCFCFEEQRLLPGETVDMPVFFFIDPEIMDDPGLKHVNNVTLSYTFFQTDMDDEEDDDDDEEDEDEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIA9</accession>
    <name>A0AAD8YIA9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIA9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="196" mass="22399" checksum="935C2FAF3690B150" modified="2024-05-29" version="1">MFHPSAATDTLQGRAIEKINKLWGEEHRGWDSYRNIGIPVCKKKYKPFDFTIQRRNEVTGEVEIKVVRLYGCHAHSNIRKAVIERHGERRGWEPFGQWSLTKAKVAARRESKRLNAQRNSSDSSDSSSGYDSSVSASSSEEETASPSFCVIKDDFQGQQPWLTLCNNGACNWKLRGKYDDIREELSEEMLCRPVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIL6</accession>
    <name>A0AAD8YIL6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_003684</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIL6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052420">
        <property type="entry name" value="Espin/Espin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153">
        <property type="entry name" value="ESPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153:SF8">
        <property type="entry name" value="FORKED, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="104"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1745760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="268" mass="30880" checksum="4576EA2DE524DEC6" modified="2024-05-29" version="1">MNAAKMMKEERVSSSESSIIQSRVRKKTTITRLVISRQWSLLEKLMKCDRFDIPIDDDSSIIVGQHSISEDLIVHFVCRFQAPFRIVVLFEEEYPESLSCFDAMGRYPLHIACAWGNSPDTIKFLIDSYPDAAMVQDANGKCAIHHLCHTFKRHYQDATHIHFNDSMMAIVKILHTAAPMSFNVEDNEGKNAVEYAIESEVNIQIIRAMQRVCRDVWLEMKEKTKNTPHDTLQMDLQRIQRDLRYQQISSNAQISKESSSERVPLTEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKF5</accession>
    <name>A0AAD8YKF5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">SP-RING finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_001611</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKF5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061665">
        <property type="term" value="F:SUMO ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16650">
        <property type="entry name" value="SP-RING_PIAS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004181">
        <property type="entry name" value="Znf_MIZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782:SF4">
        <property type="entry name" value="TONALLI, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782">
        <property type="entry name" value="ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02891">
        <property type="entry name" value="zf-MIZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51044">
        <property type="entry name" value="ZF_SP_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SP-RING-type" evidence="5">
        <location>
            <begin position="157"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1747648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="313" mass="34993" checksum="9369DFDECD41680E" modified="2024-05-29" version="1">MRCVPLHRTPKEEKKRADMHLWPLGSFVQIKFANGCDQVIPVIQRKQQSHDHSKWLGNCRPLDLTKYVTGSGTDYPLEITICTKEVIEGALERGGEVLMNSYAINVAICEYTPPDDLYNQLMGKAEGVEVLMPKLSLRSAKRMLIECIVNNTISLDSDEEEGDGKDSESDFLTFSLLCHASMTKIETPVRGQLCTHLQCFDLRNYLYTNNVVSAGRWRCPYCEKFVSVRDLVHCGLFQAILDDLDDKIVPGVRDNVCVKADGTWQLLGENKLRHKKSSSKAEAGASAAVNIEEVIGSESDGPEEIEVEVIEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKR3</accession>
    <name>A0AAD8YKR3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HEAT repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_000328</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKR3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019887">
        <property type="term" value="F:protein kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000550">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23346:SF7">
        <property type="entry name" value="STALLED RIBOSOME SENSOR GCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23346">
        <property type="entry name" value="TRANSLATIONAL ACTIVATOR GCN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24984">
        <property type="entry name" value="HEAT_EF3_GNC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24987">
        <property type="entry name" value="HEAT_EF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TOG" evidence="4">
        <location>
            <begin position="261"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="2">
        <location>
            <begin position="432"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="495"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="535"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="535"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1748389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="575" mass="61820" checksum="694BCD4A65AD6D7E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YL12</accession>
    <name>A0AAD8YL12_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">FACT complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_000460</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the FACT complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the peptidase M24 family. SPT16 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YL12"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035101">
        <property type="term" value="C:FACT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.150:FF:000005">
        <property type="entry name" value="FACT complex subunit SPT16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000017">
        <property type="entry name" value="FACT complex subunit SPT16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056595">
        <property type="entry name" value="Fact-SPT16_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048969">
        <property type="entry name" value="FACT_SPT16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013953">
        <property type="entry name" value="FACT_SPT16_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013719">
        <property type="entry name" value="RTT106/SPT16-like_middle_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040258">
        <property type="entry name" value="Spt16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13980">
        <property type="entry name" value="CDC68 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13980:SF15">
        <property type="entry name" value="FACT COMPLEX SUBUNIT SPT16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24824">
        <property type="entry name" value="PH_SPT16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08512">
        <property type="entry name" value="Rttp106-like_middle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21091">
        <property type="entry name" value="SPT16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01287">
        <property type="entry name" value="Rtt106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01286">
        <property type="entry name" value="SPT16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 10" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="FACT complex subunit SPT16 middle" evidence="12">
        <location>
            <begin position="2"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="Histone chaperone RTT106/FACT complex subunit SPT16-like middle" evidence="13">
        <location>
            <begin position="177"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="311"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="312"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="332"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="372"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1748521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="398" mass="46607" checksum="5F155DDB1A341116" modified="2024-05-29" version="1">MKEIEEKEEANLVKQDKLVRTKNERVPRLSDLTMRPVFAGRKTQGNLESHTNGLRFISTRGEIVDIMYANVKHAIFQPCENEIMVLIHFHLKNPIMVGKKKQQDIQFFTEVIDASQAVDAGKRSMYDPDEMDDEQRERQLKKRLNEAFKDFARKVEGVARKNGYSLEFDIPYRDLSFIGNPHKEMVSIQPTLNCLCNLTETPFFVVDLSDIDHVHFERVTFMSKAFDMVLVNKDFTKQPFRIDMIANEEKDSIQEWLTDMEISYTEGPMNLNWKQIMSHVLGDDRFYMDTEEDEVTAKEAGWEFLRMFGRDEADDEEGSEEESGYSEVSEKESEEDADSADEDFDTDEDDESEFDGDEDLEEQGMDWEDMEREAAADDRRKKRDGEEDVRPAKRKRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YL65</accession>
    <name>A0AAD8YL65_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_000583</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YL65"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008964">
        <property type="term" value="F:phosphoenolpyruvate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1748644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="80" mass="9153" checksum="1623F70A648B36E9" modified="2024-05-29" version="1">MLAFAECRGLGSGTMEILMETDNVDPDKIFEKLTTQKYRKISELLAHLERTDLPPFERAEALNNMRAIIAAIWGSDEIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLK0</accession>
    <name>A0AAD8YLK0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_001403</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLK0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="114" mass="12949" checksum="4861C882EC3454AC" modified="2024-05-29" version="1">MYTIDPSGGWRHRHGTIAAIGRGAERISVSSSSILEEDLTKYRIKSSGWRRALDVAMNAAINTFEKNEDNSNVDVLNNPTEKYSAWKKTVCPDDIEECYKRAIFPERQEEELVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLS3</accession>
    <name>A0AAD8YLS3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tubby family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_001585</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TUB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLS3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.90.10">
        <property type="entry name" value="Tubby Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025659">
        <property type="entry name" value="Tubby-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000007">
        <property type="entry name" value="Tubby_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16517:SF7">
        <property type="entry name" value="PROTEIN KING TUBBY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16517">
        <property type="entry name" value="TUBBY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01167">
        <property type="entry name" value="Tub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01573">
        <property type="entry name" value="SUPERTUBBY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54518">
        <property type="entry name" value="Tubby C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubby C-terminal" evidence="3">
        <location>
            <begin position="58"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1747622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="275" mass="30872" checksum="418680E7AF87BBFD" modified="2024-05-29" version="1">MEPVRIGHPRSPKQSNDSASSNNDAAVVTAPNIFALPTEVNYQAIGFVQTVVTRFGSNRYELAFQVGGVETVALIAQKVTKSMTSNYHLFDALRGGENTKMTKKAGHYIGKLRRDKDQPQGCYTLYDSSREKQQLAAFVYDIPNLVSQVKEGQPPRKMQAVIPKYSEGNALLEEETLNIKHHNNRLMEHLHNGTWQHHDLVAVQTRPPSFHEGQYRLNFQGRVLTPSVKNMQLEDQVGQTFLQFGKVDDARFHLDFKAPFTAVSAFAAALAQFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLV7</accession>
    <name>A0AAD8YLV7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000958</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLV7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1749019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="132" mass="14863" checksum="1658838ECA68E4ED" modified="2024-05-29" version="1">MELRRVEDEVKSHCKSWRDLCRPSGGACNGDSMPTLKELFSKLNDEDIFPPEPEEEPEEVEDDTQMKEDEKMVKEEKTDKEECLDSDKNSTENSISANSVPVSKPALSASESIAFSDSIFIGYIAQKEKKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMI4</accession>
    <name>A0AAD8YMI4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001819</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMI4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044772">
        <property type="term" value="P:mitotic cell cycle phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000093">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046965">
        <property type="entry name" value="Cyclin_A/B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001771">
        <property type="entry name" value="Cyclin_A_B_D_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="1">
        <location>
            <begin position="16"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="278" mass="31767" checksum="20DD5ECEDFA9BA24" modified="2024-05-29" version="1">MQHKEEILNQLHAMCAKDEQATRCHHNYFTQEVNEDCRRKMVEWSFTVVDSFNLSRESVWRAMDILDRFLSSGKGSSVKARENKQSFQLASTVCLYMAVKVHEDVEMTIGFLVKLCRSYYTASEFISMEHDILFALRWSICQTTPLDFARQCLLLQLDCFDPETIDCILENTQKQMDLATSDVYFASYKQSSVGIACLGAALVESDVNSAEQEEFWSQLSSMLNFDFASKEVREVERHMLSGSTICKPKRQSQLVLSKTTSQKSCNEQTSPVSILSCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMJ3</accession>
    <name>A0AAD8YMJ3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Parahox neighbor</fullName>
            <ecNumber evidence="7">3.5.2.17</ecNumber>
            <ecNumber evidence="6">4.1.1.97</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">QTG54_000014</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+) = (S)-allantoin + CO2</text>
            <dbReference type="Rhea" id="RHEA:26301"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15678"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58639"/>
            <dbReference type="EC" id="4.1.1.97"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-hydroxyisourate + H2O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23736"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
            <dbReference type="ChEBI" id="CHEBI:58639"/>
            <dbReference type="EC" id="3.5.2.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Purine metabolism; urate degradation; (S)-allantoin from urate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the OHCU decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.17" evidence="7"/>
    <dbReference type="EC" id="4.1.1.97" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMJ3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051997">
        <property type="term" value="F:2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033971">
        <property type="term" value="F:hydroxyisourate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000255">
        <property type="term" value="P:allantoin metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019628">
        <property type="term" value="P:urate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05822">
        <property type="entry name" value="TLP_HIUase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3330.10">
        <property type="entry name" value="Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.180">
        <property type="entry name" value="Transthyretin/hydroxyisourate hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014306">
        <property type="entry name" value="Hydroxyisourate_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018020">
        <property type="entry name" value="OHCU_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017580">
        <property type="entry name" value="OHCU_decarboxylase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036778">
        <property type="entry name" value="OHCU_decarboxylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023418">
        <property type="entry name" value="Thyroxine_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000895">
        <property type="entry name" value="Transthyretin/HIU_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023416">
        <property type="entry name" value="Transthyretin/HIU_hydrolase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036817">
        <property type="entry name" value="Transthyretin/HIU_hydrolase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02962">
        <property type="entry name" value="hdxy_isourate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03164">
        <property type="entry name" value="UHCUDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43466">
        <property type="entry name" value="2-OXO-4-HYDROXY-4-CARBOXY-5-UREIDOIMIDAZOLINE DECARBOXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43466:SF1">
        <property type="entry name" value="2-OXO-4-HYDROXY-4-CARBOXY-5-UREIDOIMIDAZOLINE DECARBOXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09349">
        <property type="entry name" value="OHCU_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00576">
        <property type="entry name" value="Transthyretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00189">
        <property type="entry name" value="TRNSTHYRETIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49472">
        <property type="entry name" value="Transthyretin (synonym: prealbumin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158694">
        <property type="entry name" value="UraD-Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00768">
        <property type="entry name" value="TRANSTHYRETIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 18" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase" evidence="17">
        <location>
            <begin position="22"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Transthyretin/hydroxyisourate hydrolase" evidence="16">
        <location>
            <begin position="217"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR600895-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF09349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1748075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="333" mass="37548" checksum="C7EE1521848AC720" modified="2024-05-29" version="1">MSSLSSPTMIPLDVLLALPTASEFLAHLGGIYEKSPTFIEQFYTENLCPTTNDASTIQATKARITNIKILFDEMKQYVRRSPSEVQLELLRSHPDLCLKLEQIDATQRDEDEATITEESRQEQGRAGLATLTPDERQNFTEWNEDYKSKFNIPFILAVRNASKYTVLSALEGRLSNVNSSPQEEIAHALFQVDKIAYMRLLEKVTYSQNQEGHGGFLTCHVLDTANGVPAAGMRIELYKYDNTDTKQMVKSFVTNSDGRLPSGPALKGAEFTVGQYQWIFYVGDYFARFSSSRICGTPFLDVVRLDFGLDDPTDHYHVPLLCSPWSYSTYRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMN7</accession>
    <name>A0AAD8YMN7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001122</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMN7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="178"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1749183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="271" mass="29993" checksum="49B4B496892F2935" modified="2024-05-29" version="1">MVMMALEGLERVLQMEGNRDSNEAESGEEGTGHQTIVKCAELIQSVIKSPHHSSAVLKRAKRVWGTHIVACALCEKYYSVRLLETHWCSECKCHVCRHCNCAVYHLSYQEELWAEDEDKQEAKKNAKKSKKAKKKEKEKAKKEKKRLETQQQAAAKPSNPRSAPSSKSAKTKDEDGKSGSNSNESGKAMSSSRGSIDDDTDYGMDGGDAVQDEVEVSSGQPPIDLVSYLQQTGSIIALAKLMDSLYENEDIDEVANEQPNVDVKQRALATQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YNH2</accession>
    <name>A0AAD8YNH2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pentatricopeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YNH2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051222">
        <property type="entry name" value="PPR/CCM1_RNA-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47942:SF63">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47942">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT (TPR)-LIKE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="531"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1056" mass="119139" checksum="DEBB410C6F129D87" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YP17</accession>
    <name>A0AAD8YP17_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000669</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YP17"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042085909" description="VWFA domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="462"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="600" mass="65013" checksum="C8FCF1823ED45BB0" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPP1</accession>
    <name>A0AAD8YPP1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="8">3.4.19.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_001163</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPP1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02257">
        <property type="entry name" value="Peptidase_C19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF98">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBP-type" evidence="7">
        <location>
            <begin position="2"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="6">
        <location>
            <begin position="235"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="78"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="387"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="80"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="111"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="123"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1749224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="576" mass="64549" checksum="3739ADABE5986877" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3V0</accession>
    <name>A0AAD9D3V0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein L13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_016479</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3V0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_uL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_uL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005823">
        <property type="entry name" value="Ribosomal_uL13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_uL13_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01066">
        <property type="entry name" value="rplM_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545:SF41">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L13, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="RIBOSOMAL PROTEIN L13"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF00572">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1732941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="178" mass="20116" checksum="F94A1358D93AAA59" modified="2024-05-29" version="1">MSFPGRAVQRTWHLVDASSQTVGRLATTIAPILKGKHKPTFRPNGDCGDYVVVINADKVHFSGKKWDDKIYRWHTGYPGGLKERPAKDMLARKPESVLKKAILGMLYRNNLRQTYMEPRLKIYAGPDHPHKAQLPDGVETLPVHPRKRKGSYHFGLGDKYSVTPFQVGLGEMPETEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4Y8</accession>
    <name>A0AAD9D4Y8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_015013</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000040">
        <property type="protein sequence ID" value="KAK1734246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4Y8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="225"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1734246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="287" mass="32557" checksum="6D2AFB1C48F88709" modified="2024-05-29" version="1">MGRKRNQGKARKAAKAMAREEAEEVQHRSNNESMTSGQQQSLTSQMLQLQVCGNASPHDTTVTCRHGFDPLFEKDICFQYANAFREAYNYKNRQDCDANLSSCLIAAHKATILDKFAEVGKDSAKMEIVTSYFLSNGTQYILEGNDDSARTCTVFARWFEQCTAVGLHKTQALINRVKIDDANNPSDIHTLVKFLRKRIPCRCLDKKYKEVKDTAKLGFCYNPECTIPNGQVERSKTFYCSRCRNVTYCSRDCQKADSTTHKHECDKFVAEIAKFEAKKQSLCTTIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5A3</accession>
    <name>A0AAD9D5A3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015802</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000048">
        <property type="protein sequence ID" value="KAK1733514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5A3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="166" mass="19134" checksum="D29BC30C7A48B4D3" modified="2024-05-29" version="1">MHDRVRIIEKEAFDGCVQLKSIKLLDVRVIKDYAFGGTMQLHGVEFGEELHTIGHMAFAHSSLEYVKLPKVRVLNSSAFYACEKLVKVDLSEDLETIHPLVFARCPHLERISLPLRPNIFQDHSVFNVYDDELDLLDNDNWIYNRHALSRVDLVGGSTAQLPRYIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6A8</accession>
    <name>A0AAD9D6A8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014797</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000038">
        <property type="protein sequence ID" value="KAK1734549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="993"/>
            <end position="1116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1157"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1263"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="308"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="329"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="398"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="446"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="463"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="473"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="512"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="552"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="567"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="593"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="623"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="680"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="773"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="828"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="860"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="909"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="934"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1003"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1013"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1023"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1048"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1076"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1163"/>
            <end position="1179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1290" mass="142488" checksum="22302969252A097B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6X8</accession>
    <name>A0AAD9D6X8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014109</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6X8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1735043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="120" mass="13887" checksum="C47C104A19103373" modified="2024-05-29" version="1" fragment="single">MARTSDRICETLDQLNDHLKSFKRFTNAKVCEVCGKETRNWNEGCILAFHNISFFGFGLTQSQSDSADFHKKQTNTWAPPTQTAIDRNKRRIRDFCKEIENDIVAAHDEDDDNRKMSLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D782</accession>
    <name>A0AAD9D782_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">alpha-L-rhamnosidase</fullName>
            <ecNumber evidence="2">3.2.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_013972</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing alpha-L-rhamnose residues in alpha-L-rhamnosides.</text>
            <dbReference type="EC" id="3.2.1.40"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.40" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D782"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030596">
        <property type="term" value="F:alpha-L-rhamnosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016007">
        <property type="entry name" value="Alpha_rhamnosid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035396">
        <property type="entry name" value="Bac_rhamnosid6H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013737">
        <property type="entry name" value="Bac_rhamnosid_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33307:SF11">
        <property type="entry name" value="ALPHA-L-RHAMNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33307">
        <property type="entry name" value="ALPHA-RHAMNOSIDASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17389">
        <property type="entry name" value="Bac_rhamnosid6H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08531">
        <property type="entry name" value="Bac_rhamnosid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bacterial alpha-L-rhamnosidase N-terminal" evidence="3">
        <location>
            <begin position="105"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-rhamnosidase six-hairpin glycosidase" evidence="4">
        <location>
            <begin position="507"/>
            <end position="736"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1735358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="799" mass="89369" checksum="2C9632FBB43234B7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7Q0</accession>
    <name>A0AAD9D7Q0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012143</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7Q0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="75" mass="8418" checksum="20C408691FCA462E" modified="2024-05-29" version="1">MIKQILQKIPGGQNVQAFVGTSILIGLCAIPVFGKDTKTGHDLFSQEKPQAIVESESKLRKDYMDTKKEQQQQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8C2</accession>
    <name>A0AAD9D8C2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8C2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1736559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="84" mass="9321" checksum="1DE3B9710A3F2D7C" modified="2024-05-29" version="1">MIIPIKVPKGRGGEDGSSSMEKIEWVMLELNGELVKPQQEAVRNTTEAEQSDKRRVELGSVQFDDAGAPTLIIGNHELKEHQSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8D3</accession>
    <name>A0AAD9D8D3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8D3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33828:SF2">
        <property type="entry name" value="NUCLEOLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33828">
        <property type="entry name" value="OS05G0596200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="119" mass="12679" checksum="B74985F736ECE4EF" modified="2024-05-29" version="1">MSDAAPKQKIGQKHPTPTPGNGDRVFYETLYNQRPESEMAQEWCVSYGVLSEEDAAKIYKKILKRKAAAKSVGGGSSSPVKSEKKKSASKKKAKKVMDDVEFDAGMGAGGDEGIGIGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8U1</accession>
    <name>A0AAD9D8U1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sulfite exporter TauE/SafE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_010536</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8U1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052017">
        <property type="entry name" value="TSUP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30269:SF38">
        <property type="entry name" value="SULFITE EXPORTER TAUE_SAFE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30269">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN YFCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="392"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="148"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="159"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1738506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="411" mass="44248" checksum="283948BDA0366281" modified="2024-05-29" version="1">MSIQLTATAADIGLLSTCAFLGTIGASLTGFGQAIIFLFVWQIVELAGYNGDFKSAVFIQALSLFSMQPLVLYKAKVWKNAHRRVLYLFVPITLVSTPIGQLVSEDVPTNIVQAVAGVLVTFVACWEMYSKRNWFLSLLSPCDNKKKNEGGGQTNADDSADHTAERGEAGVEEVGDESNDKKEEILTREVGLVDADLDEATTTAAAAGTINVGNNEEPSQKELAAAAATSTLPKPTISSVYTSLAIEPNNNIDASTAESKAARQEDEERLKIGINKPTFITLLAGGASGFLGGLVAIRGPPLIFYFLHPPHPITFNKSSQRATGVVIMFCNVLMRMIFYLINTFSVNSSGKIGFVKEDWRLYLSVIVCSIAGGLVGSKMFEYLKDSKDTIRGILSVFLLLCGVSLLFSAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D949</accession>
    <name>A0AAD9D949_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dedicator of cytokinesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_010687</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DOCK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027007">
        <property type="entry name" value="C2_DOCK-type_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026791">
        <property type="entry name" value="DOCK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23317">
        <property type="entry name" value="DEDICATOR OF CYTOKINESIS DOCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23317:SF76">
        <property type="entry name" value="LD20667P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51650">
        <property type="entry name" value="C2_DOCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2 DOCK-type" evidence="3">
        <location>
            <begin position="1491"/>
            <end position="1689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="408"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="566"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="683"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="781"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="912"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1028"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1708"/>
            <end position="1773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1996"/>
            <end position="2020"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2085"/>
            <end position="2121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="23"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="152"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="208"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
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            <begin position="219"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="242"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
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            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="298"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="422"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="589"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="687"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="718"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="917"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1751"/>
            <end position="1763"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1738657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2121" mass="228493" checksum="8FC19820B7E4B523" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAC8</accession>
    <name>A0AAD9DAC8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009046</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAC8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="158" mass="17848" checksum="A68D86300F953346" modified="2024-05-29" version="1">MHDFDIEIANIQCHGNTLHDIAKITFVLQEGRQEGRQEGSNRNDHHVEAALHSLLLDYTIHHELFGIVANHIVGLDSLNGISPQSLSSIVWAFTKVRLFHRELFDKIGDHIVQLQSLDDFNPEHISNTIWAFANASSIPHHPQLFDKIGDFIVSNNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAE0</accession>
    <name>A0AAD9DAE0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter, ABC-G family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_010553</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAE0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF139">
        <property type="entry name" value="PROTEIN SCARLET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="13"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="454"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="487"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="544"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="576"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="605"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="675"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="117"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1738523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="704" mass="77482" checksum="A6502F73451E8CFA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAE6</accession>
    <name>A0AAD9DAE6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L35a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_010568</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic ribosomal protein eL33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAE6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.190:FF:000001">
        <property type="entry name" value="60S ribosomal protein L35a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.190">
        <property type="entry name" value="translation elongation factor selb, chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00573">
        <property type="entry name" value="Ribosomal_eL33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001780">
        <property type="entry name" value="Ribosomal_eL33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038661">
        <property type="entry name" value="Ribosomal_eL33_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10902">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L35A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01247">
        <property type="entry name" value="Ribosomal_L35Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1738538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="113" mass="12486" checksum="7E4E083576076886" modified="2024-05-29" version="1">MTKQNAAPVRLYVNGAILGYKRGLRNQYNHTSLIKIKGLDSKEDAQFYLGKKVAYITKVSTAGGKNGSKFRVNWGKVCRAHGSNGVVKCKFARDLPPQSIGGRVRIMLYPSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAP1</accession>
    <name>A0AAD9DAP1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010425</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAP1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052201">
        <property type="entry name" value="LRR-containing_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24111:SF0">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24111">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="55"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="55"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="577" mass="65326" checksum="C2C079829A9EF1C8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBF1</accession>
    <name>A0AAD9DBF1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_009377</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the RBR family. RNF14 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBF1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20354">
        <property type="entry name" value="Rcat_RBR_RNF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047548">
        <property type="entry name" value="Rcat_RBR_RNF14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22191">
        <property type="entry name" value="IBR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00647">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="13">
        <location>
            <begin position="476"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="480"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1739618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="840" mass="94356" checksum="A636F13606920371" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBM2</accession>
    <name>A0AAD9DBM2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Integrase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_009602</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09272">
        <property type="entry name" value="RNase_HI_RT_Ty1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013103">
        <property type="entry name" value="RVT_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11439">
        <property type="entry name" value="GAG-POL-RELATED RETROTRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11439:SF524">
        <property type="entry name" value="RNA-DIRECTED DNA POLYMERASE, PROTEIN KINASE RLK-PELLE-DLSV FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07727">
        <property type="entry name" value="RVT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042228678" description="Integrase catalytic domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="2149"/>
        </location>
    </feature>
    <feature type="domain" description="Integrase catalytic" evidence="3">
        <location>
            <begin position="1055"/>
            <end position="1216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="524"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="872"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1285"/>
            <end position="1367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="536"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="561"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="872"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1298"/>
            <end position="1307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1356"/>
            <end position="1367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1739843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2149" mass="243796" checksum="B50CFC140C26955A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DC63</accession>
    <name>A0AAD9DC63_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SdrD B-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_006716</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049804">
        <property type="entry name" value="Choice_anch_L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051417">
        <property type="entry name" value="SDr/BOS_complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033764">
        <property type="entry name" value="Sdr_B"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF038133">
        <property type="entry name" value="choice_anch_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23303">
        <property type="entry name" value="CARBOXYPEPTIDASE REGULATORY REGION-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23303:SF15">
        <property type="entry name" value="COLOSSIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17210">
        <property type="entry name" value="SdrD_B"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117074">
        <property type="entry name" value="Hypothetical protein PA1324"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042116010" evidence="5">
        <location>
            <begin position="29"/>
            <end position="2675"/>
        </location>
    </feature>
    <feature type="domain" description="SD-repeat containing protein B" evidence="6">
        <location>
            <begin position="1323"/>
            <end position="1429"/>
        </location>
    </feature>
    <feature type="domain" description="SD-repeat containing protein B" evidence="6">
        <location>
            <begin position="1434"/>
            <end position="1554"/>
        </location>
    </feature>
    <feature type="domain" description="SD-repeat containing protein B" evidence="6">
        <location>
            <begin position="1559"/>
            <end position="1652"/>
        </location>
    </feature>
    <feature type="domain" description="SD-repeat containing protein B" evidence="6">
        <location>
            <begin position="1679"/>
            <end position="1780"/>
        </location>
    </feature>
    <feature type="domain" description="SD-repeat containing protein B" evidence="6">
        <location>
            <begin position="1795"/>
            <end position="1899"/>
        </location>
    </feature>
    <feature type="domain" description="SD-repeat containing protein B" evidence="6">
        <location>
            <begin position="1905"/>
            <end position="2027"/>
        </location>
    </feature>
    <feature type="domain" description="SD-repeat containing protein B" evidence="6">
        <location>
            <begin position="2035"/>
            <end position="2138"/>
        </location>
    </feature>
    <feature type="domain" description="SD-repeat containing protein B" evidence="6">
        <location>
            <begin position="2151"/>
            <end position="2263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="300"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="302"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="345"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="355"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="397"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="438"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="449"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="517"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="533"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="559"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="575"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="646"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="659"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="691"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="701"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="732"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="743"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="767"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="778"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="847"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1139"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1151"/>
            <end position="1319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1329"/>
            <end position="1339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1742151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2675" mass="277839" checksum="5D782A46A6ECBCC4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCD1</accession>
    <name>A0AAD9DCD1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Methionine-tRNA ligase</fullName>
            <ecNumber evidence="6">6.1.1.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_008854</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCD1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02799">
        <property type="entry name" value="tRNA_bind_EMAP-II_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000225">
        <property type="entry name" value="tyrosine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051270">
        <property type="entry name" value="Tyrosine-tRNA_ligase_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586:SF33">
        <property type="entry name" value="AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586">
        <property type="entry name" value="TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="5">
        <location>
            <begin position="76"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="28"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="55"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1740759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="243" mass="25930" checksum="04DA801551523A7C" modified="2024-05-29" version="1">MGAKSALEQLEDLIADLEAKLNLAPGADPVVAADNKKPQQQQQKQQKKKEKKQAAKQNAGKAKGGAAAPVDPNLPDICKLEFKVGVITKAWVHPDADKLYCEEIDCGEEAPRQIASGLRAHYSLEEMQGQRLLVVSNLKAKNLVGFKSFGMVLCAAETNEDGTEKVEFVEPPEGAPLGEVVTFEGLPPPAPFSASQVEKKKLFAACMGGMKTNDKCEGTFNGSVFMTTAGPCKAKSIKGGAMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCZ3</accession>
    <name>A0AAD9DCZ3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">C2 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006364</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010828">
        <property type="term" value="P:positive regulation of D-glucose transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090314">
        <property type="term" value="P:positive regulation of protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031340">
        <property type="term" value="P:positive regulation of vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072659">
        <property type="term" value="P:protein localization to plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038983">
        <property type="entry name" value="C2CD5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057815">
        <property type="entry name" value="C2CD5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056430">
        <property type="entry name" value="C2CD5_YbjQ-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056431">
        <property type="entry name" value="C2CD5_YbjQ-rel_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035439">
        <property type="entry name" value="UPF0145_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37412">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37412:SF2">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23025">
        <property type="entry name" value="YbjQ_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23028">
        <property type="entry name" value="YbjQ_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23128">
        <property type="entry name" value="YbjQ_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117782">
        <property type="entry name" value="YbjQ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="951"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1010"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1061"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1089"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1125"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1135"/>
            <end position="1150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1551" mass="170884" checksum="DEBA8B4FF482FD39" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDX3</accession>
    <name>A0AAD9DDX3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WRKY transcription factor 19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006703</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDX3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="202" mass="21848" checksum="870DC491E7AD227B" modified="2024-05-29" version="1">MVKEEDYAALIYQDTMRRRAEAAAIAKVAAAKSSESRPRRTSPRLMDNDGSTKSEVKEAPKKKRKSADDSDTEHSAQKQKRRKKNEKMCSADSCKEVKGGVCIKHGAKVAFLCTFQGCPNQVKRGGVCFRHEAGAVAKALKNGGVCIRHGATVKLCSSEGCTNQVRSEGVCFRHGAKVKLCSNEGCTNQVKSGGVCINYAAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEP1</accession>
    <name>A0AAD9DEP1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_006592</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEP1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45667">
        <property type="entry name" value="S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041974180" evidence="11">
        <location>
            <begin position="36"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="344"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="100"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="180"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="278"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1742995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="369" mass="38933" checksum="D39C7B17597BE110" modified="2024-05-29" version="1">MSTMAVSARSRSKAPCRVFFCTILCLSLLILPSRATKVCQTFQPLKRNQLNMGTTMVVAAAATFPRGGGAAKITATTAPAASSTTISSALILKSFLKTIADARSHLAAAAAARAVSIFSMYPVDTIKTRMQMKQGDAFRLSGLYKGCAGSLVGQVPYGVLTFGSYEIYKQALLNKFPNTKPALIYALSAILGDVTGSGWLCPSEVMKQQLQAGLYPSMSEAIKGIWSKSGIAGFYQGFTGGLARDVPFRVAQLTTFEVTKSLYLKAKKGRTGDDNAALSAVEAAVCGAAAGSFSAAITNPLDRIKTLMMTDTANAYGGSVVACASKILKDEGIGGLFAGVAPRVGYIAPSVCIFFVTYEFVQQKMQKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEW5</accession>
    <name>A0AAD9DEW5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_005841</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEW5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="142"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="254"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="492"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="84"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="254"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="516"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="539"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1743220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="554" mass="62744" checksum="12771C83371900A1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DF47</accession>
    <name>A0AAD9DF47_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DF47"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="110" mass="12628" checksum="E9E48825C64DB8F4" modified="2024-05-29" version="1">MSVESTGVRCMLLGQRQNSERQKSAVFISGRSYSIRYVESEEEFNKFTEDLNEIKNTIAALNEIHQNGQMTERTYRERLTSDWLDGCVASFISAYGLDSVPMTSELRLMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFP7</accession>
    <name>A0AAD9DFP7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1746021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFP7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="153" mass="17256" checksum="1447200FF4FC84C1" modified="2024-05-29" version="1">MTVLTLFASFNPPVLCKYMSSAPRCLVFVTGQTFAANLRGNENYSRELSRPKLRKKRRPDPWEMEDKDDSNDWEVEEEEIIDFFYWEDGDDLEEAAAAVEKQFAEFEAAVSALSDTDIAMSDTSVTTGTSSSAAIASVSTWFLLVTVPIWYLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHD1</accession>
    <name>A0AAD9DHD1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sel1-like repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002566</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHD1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="137" mass="14971" checksum="D3AFDA084CF6C9A9" modified="2024-05-29" version="1">MGRRRYKEGNTKSAFGYYSKATELGDVGAHFSLSLMYQEGLGVEKDEKKEVHHLEEAAIGGHPKARHNLGFVELINGRDARAVKHLIIAANMGHDGSLVALKLCYRKGLISKENFAAALRGHQAAVDSTKSPQREAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHM4</accession>
    <name>A0AAD9DHM4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001485</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHM4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="248" mass="26092" checksum="F6D87C3DE03B7820" modified="2024-05-29" version="1">MEAYGPVKDLKLVTDKKATEESRYETSLSCCRWDEIGGTCNSRGCGTGTYGAELVAETTGGGLGGTRLGGKDKNIFMAGRFDPSKQPVMPPPPPQMMGMGPPHPHHGPPGGMGPGGPMGPPGFGGPGRVVHRNMDTTMIVDLLLVMAVVAVDMMIVVHLLDMVVAVDLMIVVHRLGMAAGGEGTMIVGLHLGIISVGDMVVVVVVTMMVDMEVIGREEDHPVRQDVGGTNVQVNSKCIRCVVIAYDCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHN0</accession>
    <name>A0AAD9DHN0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHN0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="148" mass="17182" checksum="3491E1D7F7DB9690" modified="2024-05-29" version="1">MIKYTQGYYSFHTLFIVYGSSLYKACFCAVISSVLYFLYYWFYIHEVINLLDHPYPVAAVVSSVAIALSFKLTFSYNRWWEACTTLHNMHAKWLDVGSTMAAFHLQSRIYESVHRLHLGSIKMSILTLFVGVKLLKEQVQASLRHVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHV2</accession>
    <name>A0AAD9DHV2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Molybdenum cofactor sulfurase</fullName>
            <ecNumber evidence="3">2.8.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003276</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.9" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHV2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008265">
        <property type="term" value="F:molybdenum cofactor sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005303">
        <property type="entry name" value="MOCOS_middle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237:SF80">
        <property type="entry name" value="MOLYBDENUM COFACTOR SULFURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SULFURASE MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03473">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03476">
        <property type="entry name" value="MOSC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141673">
        <property type="entry name" value="MOSC N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="MOSC" evidence="2">
        <location>
            <begin position="882"/>
            <end position="1051"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1051" mass="117410" checksum="8C8463E059F632AD" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DI65</accession>
    <name>A0AAD9DI65_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003277</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DI65"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="144"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="225"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="635" mass="70512" checksum="17C60B175DD2F964" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJE8</accession>
    <name>A0AAD9DJE8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha and gamma adaptin binding protein p34</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJE8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11960">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019341">
        <property type="entry name" value="Alpha/Gamma-adaptin-bd_p34"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14659">
        <property type="entry name" value="ALPHA- AND GAMMA-ADAPTIN-BINDING PROTEIN P34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14659:SF1">
        <property type="entry name" value="ALPHA- AND GAMMA-ADAPTIN-BINDING PROTEIN P34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10199">
        <property type="entry name" value="Adaptin_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="372" mass="40501" checksum="5BA2566B7642DDCE" modified="2024-05-29" version="1" fragment="single">SLLRSLDRIATLEIEHTNNIISVANLNHRSIMSCHSIVRIGPLNSDDGCYATILRSSITNYFSSSSSNEDNDTKNDPHRLAISNRYFDASVAFAGLNQSTDDVITASESAVEDGIILVCDSSLSASQGMCFDSLNKLHDNAEKSTDLGDLLRLCVGVSFGPSPLADGTKASEEEYSRRVLWCLDRGYEYVEADMSLVGMESGHNDRDKEGFARIIEAISSCMWSSHVMKKRTAAATTSVTAANIGSGNTQSQPNEKANADTTASAVPTSDSEREKAAVANLMEGVDQDIESKNKAEEIKKQELAFHELERVIADAKNIRESSQNDSISDEERRKLAGDTALRMMDLFDKLGFGDDEEDSDETEASSLPEGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJK5</accession>
    <name>A0AAD9DJK5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000453</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJK5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="67" mass="6934" checksum="358DC20AF1BD5F61" modified="2024-05-29" version="1">MELDLTSPIVPTGKATKEVKSTPKKTPKPSILSPASTKKAAKGAGSVATPAGRRSARIARKSMDKDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DKC4</accession>
    <name>A0AAD9DKC4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000482</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DKC4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071203">
        <property type="term" value="C:WASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019309">
        <property type="entry name" value="WASHC3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10152">
        <property type="entry name" value="CCDC53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="186" mass="20657" checksum="166F6CDEEA420347" modified="2024-05-29" version="1">MAAAALPPLPSVRAKELESRASALSRRHASTDDDDRNIDANDKNAQSEQTELVEKPYSSLHEKNIQSNIEASTLAAEQQHRERLEQIEMLHQKEQKVFDQLPPLDPTVTCDAIHQYLSTTSQFLNSYIADANASLEGTSHKLSVLEKQMSLLESKLESIPGLFSEDEEQSVNATDQDNIIDNVAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-12-02" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6V0ZIP8</accession>
    <name>A0A6V0ZIP8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Autophagy-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_002980</name>
        <name evidence="7" type="ORF">SMAR1039_LOCUS555</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">FE7</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ATG8 family.</text>
    </comment>
    <dbReference type="EMBL" id="HBGM01000794">
        <property type="protein sequence ID" value="CAD9313431.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6V0ZIP8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16128">
        <property type="entry name" value="Ubl_ATG8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004241">
        <property type="entry name" value="Atg8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10969">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02991">
        <property type="entry name" value="ATG8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0072">Autophagy</keyword>
    <keyword evidence="4 5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="lipid moiety-binding region" description="Phosphatidylserine amidated glycine; alternate" evidence="5">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604241-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CAD9313431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1746373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="117" mass="13516" checksum="93894CF42B5DFE62" modified="2020-12-02" version="1">MSKSFKEEHPLEKRKSEAERIRAKYPDRVPVICEKADRSDIPDIDKKKYLVPADLTVGQFHYVIRKRIQLAPEKALFLFCSNTIPPNAALMSTVYEEQKDEDGFLYVQYSGESTFGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2L0X7</accession>
    <name>A0A7S2L0X7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003461</name>
        <name evidence="2" type="ORF">SMAR0320_LOCUS7097</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="HBGZ01009941">
        <property type="protein sequence ID" value="CAD9591381.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S2L0X7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CAD9591381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="141" mass="16179" checksum="2CCAE778892CEB8F" modified="2021-06-02" version="1">MLQPLSENYSHQFDEEAVPDHLESVEEEEGIDKDRWDEGGRSDCGYTDTIHDTLMTVGSWMHGLFGEPTEEMNMQMKGIGNYFQEASYAVRDFRRGTIEEGEFNFEADDLDLDLDGLDIDEDVSDEYELPSDDEPSDEEGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2L8J3</accession>
    <name>A0A7S2L8J3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">Malate synthase</fullName>
            <ecNumber evidence="2 8">2.3.3.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_007259</name>
        <name evidence="13" type="ORF">SMAR0320_LOCUS9522</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>glyoxylate + acetyl-CoA + H2O = (S)-malate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18181"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the malate synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.9" evidence="2 8"/>
    <dbReference type="EMBL" id="HBGZ01013273">
        <property type="protein sequence ID" value="CAD9598573.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S2L8J3"/>
    <dbReference type="UniPathway" id="UPA00703">
        <property type="reaction ID" value="UER00720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004474">
        <property type="term" value="F:malate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00727">
        <property type="entry name" value="malate_synt_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1220.12:FF:000001">
        <property type="entry name" value="Malate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.360:FF:000001">
        <property type="entry name" value="Malate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.360">
        <property type="entry name" value="Malate synthase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1220.12">
        <property type="entry name" value="Malate synthase, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044856">
        <property type="entry name" value="Malate_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011076">
        <property type="entry name" value="Malate_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006252">
        <property type="entry name" value="Malate_synthA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019830">
        <property type="entry name" value="Malate_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001465">
        <property type="entry name" value="Malate_synthase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048355">
        <property type="entry name" value="MS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048356">
        <property type="entry name" value="MS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046363">
        <property type="entry name" value="MS_N_TIM-barrel_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01344">
        <property type="entry name" value="malate_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42902">
        <property type="entry name" value="MALATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42902:SF1">
        <property type="entry name" value="MALATE SYNTHASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20659">
        <property type="entry name" value="MS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20656">
        <property type="entry name" value="MS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01274">
        <property type="entry name" value="MS_TIM-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001363">
        <property type="entry name" value="Malate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51645">
        <property type="entry name" value="Malate synthase G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00510">
        <property type="entry name" value="MALATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 8" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Malate synthase N-terminal" evidence="11">
        <location>
            <begin position="10"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="Malate synthase TIM barrel" evidence="10">
        <location>
            <begin position="173"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="Malate synthase C-terminal" evidence="12">
        <location>
            <begin position="430"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="76"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001363-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF20656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF20659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CAD9598573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1741686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="564" mass="63134" checksum="32B8B80BF7C6CE05" modified="2021-06-02" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1H185</accession>
    <name>A0A8K1H185_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Large ribosomal subunit protein bL35c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rpl35</name>
        <name evidence="6" type="ORF">QTG54_017230</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="7"/>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2021" name="Front. Plant Sci." volume="0" first="0" last="0">
            <title>Chloroplast Genomes for Five Skeletonema Species: Comparative and Phylogenetic Analysis.</title>
            <authorList>
                <person name="Liu S."/>
                <person name="Xu Q."/>
                <person name="Liu K."/>
                <person name="Zhao Y."/>
                <person name="Chen N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CNS00100</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Plastid</location>
            <location evidence="5">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL35 family.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MW679506">
        <property type="protein sequence ID" value="UAM91429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_010200943.1">
        <property type="nucleotide sequence ID" value="NC_058701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1H185"/>
    <dbReference type="GeneID" id="68638082"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.410.60:FF:000001">
        <property type="entry name" value="50S ribosomal protein L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00514">
        <property type="entry name" value="Ribosomal_bL35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001706">
        <property type="entry name" value="Ribosomal_bL35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021137">
        <property type="entry name" value="Ribosomal_bL35-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018265">
        <property type="entry name" value="Ribosomal_bL35_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037229">
        <property type="entry name" value="Ribosomal_bL35_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00001">
        <property type="entry name" value="rpmI_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33343">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN BL35M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33343:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL35M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01632">
        <property type="entry name" value="Ribosomal_L35p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00064">
        <property type="entry name" value="RIBOSOMALL35"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143034">
        <property type="entry name" value="L35p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00936">
        <property type="entry name" value="RIBOSOMAL_L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 7" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00072523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1732187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UAM91429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="64" mass="7483" checksum="C010664ED20D0794" modified="2022-08-03" version="1">MPKLKTRKAALKRYKKTGAGNFLRRHAFKGHLLMKKSNVQKRRLSQRVCVTKSDSKPIKLMLPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRU4</accession>
    <name>A0AAD8XRU4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WRKY transcription factor 19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016643</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000061">
        <property type="protein sequence ID" value="KAK1732666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRU4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="212" mass="23191" checksum="702CF3EB6D2C77FA" modified="2024-05-29" version="1">MSTKQRAEAATATKVVEEDDIGALIYKESQLRKKEAAAAKNIERRSSSASKHRATSTHKDTAAAIRGDSSFATPDSRQLIEKRKRHLPTDVDEGKEPAEKVARKKYRYECSADGCTNHVVKGGVCKRHGAKPKIKKCSSDGCTNQVQHSEGCTNQVVKGGVCIKHGAKPMVRQCSNEGCSNIVIRKGVCWTHGAKHNRCISRKDVPISIKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XT06</accession>
    <name>A0AAD8XT06_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_016013</name>
        <name evidence="2" type="ORF">QTG54_016714</name>
        <name evidence="3" type="ORF">QTG54_016718</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000063">
        <property type="protein sequence ID" value="KAK1732573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000063">
        <property type="protein sequence ID" value="KAK1732577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000051">
        <property type="protein sequence ID" value="KAK1733296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XT06"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1733296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="78" mass="8702" checksum="6BC8B45147F770A7" modified="2024-05-29" version="1">MTINYIGLVILIIGGLFLLMAIAQPKNFIVYKGLIARSEVCWGEGNGPKVMAAYSLMMIVFGLLLMFRVFGKQDEKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTX0</accession>
    <name>A0AAD8XTX0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA mismatch repair protein MutS family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_015792</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000048">
        <property type="protein sequence ID" value="KAK1733504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032301">
        <property type="term" value="C:MutSalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20404">
        <property type="entry name" value="Tudor_Agenet_AtEML-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="entry name" value="MutS, connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF148">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55271">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair protein MutS core" evidence="3">
        <location>
            <begin position="742"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="157"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="203"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="46"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="219"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1733504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1340" mass="148676" checksum="1288F8C866ABD395" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUC6</accession>
    <name>A0AAD8XUC6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WRKY transcription factor 19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015766</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000047">
        <property type="protein sequence ID" value="KAK1733593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUC6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="342" mass="36921" checksum="F4E156899DD34C77" modified="2024-05-29" version="1">MKQATPKKKAVVQKEEEKDDIESQFRKREAEVAAIKKGSHADITRRRSSRLASAAITAARDAKLIVTVKKEATAKSKKRPCSDDAVVPRKVARKQYRNKCSADTFVGACKNDEANVKVELCTSEGFATFGRGGEVHGRPRAKKTCAIKGCTKGSRRKGGVCKSHGPELKLCSTDKCTNIAKGGGVCQRHKARRYICSSVGCTNVSYKGGACKRHGAKVKGGVCKRHGAKVPRCRTKGCPNGAVQGGVCVRHGAKVRLCSFPECTNQAKMRGVCIKHGAQGKPPCSVEGCTNKSVNKGVCQRHGAKIKRCSMKGCTNQVVKGGGVQKTWSKTRMLCRWMHESC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUC9</accession>
    <name>A0AAD8XUC9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fidgetin-like protein 1</fullName>
            <ecNumber evidence="7">3.6.4.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_015804</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000048">
        <property type="protein sequence ID" value="KAK1733516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUC9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000022">
        <property type="entry name" value="Fidgetin like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000093">
        <property type="entry name" value="Fidgetin-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050304">
        <property type="entry name" value="MT-severing_AAA_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015415">
        <property type="entry name" value="Spast_Vps4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074:SF17">
        <property type="entry name" value="FIDGETIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09336">
        <property type="entry name" value="Vps4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="99"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1733516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="354" mass="39376" checksum="4415D416290402FE" modified="2024-05-29" version="1">MKSSLETISEGGGLSVGEPTRKTTAEPKKRTATRSQRGEKLPHRLEKELVQKINNEIVVTGQEVTFDDIAGLEDTKNTVKEMLIYPMKRPDLFTGLRTCPKGLLLFGPPGTGKTMIGKAIAHESGATFFSISASSLKSKWIGEGEKLVKTLFAVASYQSPSVVFIDEVDSMLTQRKSDEDEASRSMKNEFLVQLDGAGNETKGHVIVIGATSLPHELDDAARRRFVKRLYFPLPDQAVREQQLRTLLANNRHSLKDSEITKLSHATDGYSCADLKNLCTDASMGPMRSLTDDEMMSINADEVPPISYKHFRRSLRGMNPSVAQSDLQVYLDWNDKYGSKVSNNLDDYRRPGRKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUR4</accession>
    <name>A0AAD8XUR4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015377</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUR4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="260" mass="28684" checksum="A95DB4DA54AEB490" modified="2024-05-29" version="1">MIAAQLPNNNSDDDGGEEEHAVLPTVDTPTPYTPKEKYRADRDPNVEQLQFPPLAPGVLETYKWANGDPYDGLSARIGIPPQLKDTIIAYAKGLGIWDIILNTMEPENQMRPDSTKILTVASPYSGQNFTWSVKRPDNFEGSSSDMHWFDIAVVVFFFILCSTRRSTSSTCQGGFDEVLNAIGTYLGLDNLVSFSIGILAVTKADKGYVHVDFSKSGKKAANFLVNLQTPGDDPELTVIEEDDVGNRRVPRSSTQMNLVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVC7</accession>
    <name>A0AAD8XVC7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Bestrophin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_015284</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1734026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044669">
        <property type="entry name" value="YneE/VCCN1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281">
        <property type="entry name" value="UPF0187 PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281:SF19">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION CHANNEL-FORMING PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25539">
        <property type="entry name" value="Bestrophin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="612"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="839"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="633"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="698"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="741"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="767"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="873"/>
            <end position="886"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1734026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1326" mass="148709" checksum="0F7062E2DE5E15DA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVC9</accession>
    <name>A0AAD8XVC9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Prolyl 4-hydroxylase alpha subunit-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_014804</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000038">
        <property type="protein sequence ID" value="KAK1734556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVC9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF226">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042188073" evidence="7">
        <location>
            <begin position="27"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="8">
        <location>
            <begin position="424"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="37"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="55"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1734556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="551" mass="60375" checksum="C4D5360A295BCB65" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVJ7</accession>
    <name>A0AAD8XVJ7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">G protein-coupled receptor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_015052</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000040">
        <property type="protein sequence ID" value="KAK1734285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVJ7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="225"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1734285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="429" mass="48417" checksum="AD6E370D030097AC" modified="2024-05-29" version="1">MSNEASYTWQQKWIAIAPKPFSLLSILGSSYILKHILTSKERRSQVYHHILLGLCAYDIIASFTMFWGTWAIPSGTPNVYLASGTIGTCNAQAFLQQLGVAVPIYTAELAAYYFLVVAFGWKERQLKRIEILLHLIPSALGWTSSIVGIATNSFSDSVFWCWYSPDKYGLRFGFFYGIVWACILLVCLLMALMYMKVLMQERKVKKYQHPNVVGATQTDTDRQTKQQRREKKASASKKIAAQAILYSGSFILTWLFASWARIYEMVNGKDAPFAIQALFTIFSPLQGFFNMWIYFRPRYARYRLDHPDFSITRFICDCGGLRSRLRTSGGSARANSTYRVGFDPAVANDLHDSSNAADKLSSKSATIKKLATNGDNRHCRNSTMKVVAGEDGGIEEENDPCQRQSTVRFADVNIGIEEEKVEEIADMIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVY1</accession>
    <name>A0AAD8XVY1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">N-acetylgalactosamine-6-sulfatase</fullName>
            <ecNumber evidence="8">3.1.6.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_014832</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.4" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000038">
        <property type="protein sequence ID" value="KAK1734584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVY1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043890">
        <property type="term" value="F:N-acetylgalactosamine-6-sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050738">
        <property type="entry name" value="Sulfatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42693:SF11">
        <property type="entry name" value="ARYLSULFATASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42693">
        <property type="entry name" value="ARYLSULFATASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14707">
        <property type="entry name" value="Sulfatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00149">
        <property type="entry name" value="SULFATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042212817" evidence="6">
        <location>
            <begin position="30"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase N-terminal" evidence="7">
        <location>
            <begin position="42"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="62"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1734584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="619" mass="68206" checksum="59D885098F0A611A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW62</accession>
    <name>A0AAD8XW62_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014656</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XW62"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="600"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="609" mass="64729" checksum="FE4C851AD44B7426" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWD8</accession>
    <name>A0AAD8XWD8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Serine/threonine-protein kinase</fullName>
            <ecNumber evidence="14">2.7.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_014180</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="14"/>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWD8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030553">
        <property type="term" value="F:cGMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050205">
        <property type="entry name" value="CDPK_Ser/Thr_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24349">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0140">cGMP</keyword>
    <keyword evidence="8" id="KW-0142">cGMP-binding</keyword>
    <keyword evidence="6 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="100"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="13">
        <location>
            <begin position="435"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="12">
        <location>
            <begin position="492"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1735114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="633" mass="70805" checksum="DFDEFBE5797401C0" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWY6</accession>
    <name>A0AAD8XWY6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_014055</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWY6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="7">
        <location>
            <begin position="17"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="83"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="268"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="272"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="299"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1735441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="311" mass="34932" checksum="09CB7EB534498C51" modified="2024-05-29" version="1">MSADDCEAGVMTMMSCCASCGIAEADDIKLKECPTCDLVRYCSDECQENYTSQHKEACMKRAVEELRDDLLFKQPESSYLGDCPICMLPMPLDLSKSIVAVCCSKSICRGCFHANYMSEEEGWSNRRCPFCREPVSSKMEECDKQRMKRIEANDPVALCEEGAAELGDVDAHYRLSDLYRNGRGVVKDGEKEVHHLEVAAIGGHPRARYNLGCHEWNNGNSERAVKHWIIAAAQGHDGSIKALMYEFRRGFVSKDDLAAALRAHQAAVDATKSPHREVAETQREAAEEYIRSQSPQRQAAEDYRRKMKSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXD9</accession>
    <name>A0AAD8XXD9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXD9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="301" mass="32567" checksum="86E34B3C7D7189BE" modified="2024-05-29" version="1">MKNIICSGLQRAETQIGSKANMAWTLRYTLDALLEEMGFTVTSNEQAWRPDPTMNEYQCIGVTTAFTPLQTEISEAPDYEDNANAAVSSFANTDDVSTSETPTSSASFCSVPFVLIVTTVILAAYCDGFSTSYPTRKSHRCRLHNYSSQLLSSSQSNEQQQPQMNGPSPIITPPPPELNRVPLPAMLAGGLFLFATSVPSSQRSRADKLLRLAQEALRSDPVVTMELGPGIEAGNVYASSKGTVGNVDQLVLQFQINGGNAWAQGITYGVEDENSLRLVALEVANMDAVLNNQSFQVPLNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYI8</accession>
    <name>A0AAD8XYI8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_013209</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYI8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF288">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1736073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="143" mass="16082" checksum="7B423246BE9E9350" modified="2024-05-29" version="1">MTHGVGTACWMAPEVLKHARSSKYSDVYGFGIVLWELATRSQVYEGLESTQIIAMVANDNLRPEVPDGCPWNDLMVKCWNEAPQDRPSFEDIVRELNRLRPVVRNSKYTGESLKVPKWKANSYQRGGSKSGSQPKVTVPRQTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYL2</accession>
    <name>A0AAD8XYL2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012884</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYL2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026898">
        <property type="entry name" value="PrsW"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13367">
        <property type="entry name" value="PrsW-protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="427"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="457"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="487"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="662"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="732"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="774"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="843" mass="95164" checksum="3B520E9AD8F088D4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYQ2</accession>
    <name>A0AAD8XYQ2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.10">
        <property type="entry name" value="Bactericidal permeability-increasing protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31138">
        <property type="entry name" value="CHROMOSOME 19, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31138:SF1">
        <property type="entry name" value="PDZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1518" mass="164857" checksum="DADD994035FACA96" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYS5</accession>
    <name>A0AAD8XYS5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoglycerate mutase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000031">
        <property type="protein sequence ID" value="KAK1735933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYS5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47821">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47821:SF2">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041957636" evidence="1">
        <location>
            <begin position="28"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="277" mass="30818" checksum="A65CDF03DA62DC7D" modified="2024-05-29" version="1">MMPSFQLANKHQRLSSLLLLLPTAARAALSTTSSSPTIINHLLHRPHLTHSYYALRHGQSLANVAQIISSDPQISTVQHGLSKVGQEQATLAGKSFAKQYLNDASSSKNVNYKGVAIFSSDFTRARETATLFTQQLHNHQEIPIYTNDIVLETRLRERYFGELNGGPDDQYQKVWDVDCTNPNHDEFGVEAANCVLERTTRLVTELDELLSSSTASTTAASSSSNGSEEEQKWKVILVAHGDVLQIMQTGFLRHEDAARHRSLEHLETATIRELILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZ61</accession>
    <name>A0AAD8XZ61_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012636</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZ61"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="344"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="395"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="441"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="569" mass="63873" checksum="1970F00511A5FA55" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0U0</accession>
    <name>A0AAD8Y0U0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA polymerase phi</fullName>
            <ecNumber evidence="8">2.7.7.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_012752</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16841">
        <property type="entry name" value="RraA_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.40">
        <property type="entry name" value="Ribonuclease E inhibitor RraA/RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007015">
        <property type="entry name" value="DNA_pol_V/MYBBP1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005493">
        <property type="entry name" value="RraA/RraA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036704">
        <property type="entry name" value="RraA/RraA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13213:SF2">
        <property type="entry name" value="MYB-BINDING PROTEIN 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13213">
        <property type="entry name" value="MYB-BINDING PROTEIN 1A FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04931">
        <property type="entry name" value="DNA_pol_phi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03737">
        <property type="entry name" value="RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89562">
        <property type="entry name" value="RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="7">
        <location>
            <begin position="1443"/>
            <end position="1508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="627"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="936"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1375"/>
            <end position="1416"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1037"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1832"/>
            <end position="1859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="40"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="54"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="633"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="944"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="984"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1395"/>
            <end position="1408"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="1667"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="1668"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR605493-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1736730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2000" mass="219416" checksum="2FDD226D5468DFCF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y129</accession>
    <name>A0AAD8Y129_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Acid phosphatase family protein</fullName>
            <ecNumber evidence="1">3.1.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012075</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y129"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010036">
        <property type="entry name" value="MDP_1_eu_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17901:SF14">
        <property type="entry name" value="MAGNESIUM-DEPENDENT PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17901">
        <property type="entry name" value="MAGNESIUM-DEPENDENT PHOSPHATASE 1 MDP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12689">
        <property type="entry name" value="Acid_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="265" mass="29238" checksum="18464497A3E79AC5" modified="2024-05-29" version="1">MSRRRILSAIVVAATNSFRSAAFLVPHKTANVSTQLKLSSDGPFPSKMGAGHGPFPYLCVFDLDACFWDQEMYTLSKICDSSNVVKGDLNGRGEGVVGVMSGRSKISLHTGSLIALQNHFDNKFDNMKVCFASSADTPLAEKIGRSALKLLEVVPGVSVWDLVVDRDWDGEDINQIGRQPPLSSNKAATHFPILRELTKVPYDRMLFFDDCQWGDHCGMVEARCKESESGRGPTTVRTPYGLGREEWAEGLSKYAKNIKNEMNVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y167</accession>
    <name>A0AAD8Y167_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Ribosome recycling factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_011859</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RRF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y167"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00520">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.20:FF:000001">
        <property type="entry name" value="Ribosome-recycling factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.40:FF:000001">
        <property type="entry name" value="Ribosome-recycling factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.20">
        <property type="entry name" value="Ribosome-recycling factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00040">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002661">
        <property type="entry name" value="Ribosome_recyc_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023584">
        <property type="entry name" value="Ribosome_recyc_fac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036191">
        <property type="entry name" value="RRF_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00496">
        <property type="entry name" value="frr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982:SF3">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME RECYCLING FACTOR PSEUDO 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982">
        <property type="entry name" value="RIBOSOME RECYCLING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01765">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55194">
        <property type="entry name" value="Ribosome recycling factor, RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042175135" evidence="10">
        <location>
            <begin position="20"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="546"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="612"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="672"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosome recycling factor" evidence="12">
        <location>
            <begin position="78"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="SLC26A/SulP transporter" evidence="11">
        <location>
            <begin position="263"/>
            <end position="668"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1737573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="714" mass="75110" checksum="2651246947A41ECE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1J3</accession>
    <name>A0AAD8Y1J3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011183</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1J3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="26" mass="2894" checksum="493B7A0DC781DFAB" modified="2024-05-29" version="1">MKPKFIFLDEITSGLDSENAVVVIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2A0</accession>
    <name>A0AAD8Y2A0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_010978</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2A0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000018">
        <property type="entry name" value="S-adenosylmethionine mitochondrial carrier protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45667">
        <property type="entry name" value="S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="9"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="97"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="198"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1738309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="292" mass="31061" checksum="849AEDC43EB6E8D6" modified="2024-05-29" version="1">MAPDKERHTPFLTSLIAGGMAGTTVDLALFPIDTLKTRLQSPQGFVAAGGFRGVYRGIMAAAAGSSPGAALFFGTYETMKPVIANLQSTYRGEEASSPALTHMISASIGEAAACLVRVPTEVVKSKMQTNAAGASSLSATFKLVVSEKDGRAFGSQVFGGLYRGYGITLMREVPFAFIQFPMYERLKVELAKIQGFETSPLQAATCGSFSGGIAAAFTTPLDVVKTRLMLGSDKNGVKYHGANDVIGRILKEEGTPVLLSGIQPRVMWISIGGFVFFGAYESYRSLLMNLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y386</accession>
    <name>A0AAD8Y386_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011269</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y386"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="301" mass="32862" checksum="E1C99E7550978107" modified="2024-05-29" version="1">MNGQEGKQIGQVFQNPISFPDEDGNYHQNSSSVGINQGYSFNFPDDPHPMGNRQFLFGKDDKMIVFNEIVMHATGPFAKFIGATLSEEVVSNDPNYVADITVAVPTSTPDPDTTGNDAYIREEGATYDFRITANGGFYDPIQSVNGEGKLEQIGERFQNPVYTYSGNRVGTNQGYAFIFPVTNFTREMTMGNRVFPLQNGTLNVFNEIIVKATGIYSEFTGGRFKEVVVSANPDFVSEITLILPSVNQKEEDDGAEKEDNVESAEKEGDGNEGASMTSGGDSVLLTPTLFGLGVVLLQSMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4G2</accession>
    <name>A0AAD8Y4G2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histidinol dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010193</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4G2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004399">
        <property type="term" value="F:histidinol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1980">
        <property type="entry name" value="Nitrogenase molybdenum iron protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012131">
        <property type="entry name" value="Hstdl_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256:SF2">
        <property type="entry name" value="HISTIDINE BIOSYNTHESIS TRIFUNCTIONAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256">
        <property type="entry name" value="HISTIDINOL DEHYDROGENASE HDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00815">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="128" mass="13833" checksum="03AB58B35A0992DA" modified="2024-05-29" version="1">MYCHVGQIGTRALGNSNENSQEVADRCANYGGLFIGTHAAEVLGDYGAGPNHTLPTGGTGRYTGGLSVFNFLRIRTWMRIDNKKESQDMVEDSVRMARLEGLEGHARAAEARSLTLTPAYKKANNGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6P4</accession>
    <name>A0AAD8Y6P4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cilia- and flagella-associated protein 52</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_009128</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
            <location evidence="1">Flagellum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the CFAP52 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6P4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031514">
        <property type="term" value="C:motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050630">
        <property type="entry name" value="WD_repeat_EMAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720:SF14">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720">
        <property type="entry name" value="WD-40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="17"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="68"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1740178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="634" mass="71092" checksum="42B6EC6EACCE8C64" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7B9</accession>
    <name>A0AAD8Y7B9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-CH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_009021</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7B9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-CH-type" evidence="4">
        <location>
            <begin position="7"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1740071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="177" mass="20315" checksum="0342E13619258DBF" modified="2024-05-29" version="1">MMKAAAALPEDAPCCWLCLEEGPESSGQPLVRDCSCRGTSGFAHLSCMITNARHHGRQAVEDDGPYFELSTCFESCPNCKQLYQDNLHYEMLKSLIAFVDEEFEDMEYRHLQVCSRRDTIRNVDVENIEDRSKGEAMVTKMLSLMEQLKYYDHWTMGDIELEVSVYSAICDFYYNTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7C2</accession>
    <name>A0AAD8Y7C2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008363</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7C2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1741111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="513" mass="57642" checksum="A99345AAFF85F950" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7D8</accession>
    <name>A0AAD8Y7D8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008393</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7D8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1741141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="262" mass="29182" checksum="ED85A99EEC8B3975" modified="2024-05-29" version="1">MATPAAASSPTSSSSSSMITSLLETVGIEIFICYLRPSNLISLSLTSHQLHDTILQPTTLIQICSQHYLPIQLGVNTNYLAELTLLGDDNNSHRSKRELVDHVLDKLHTSQLLLVNTNSIHDSEKKAKQLFLDENKSSAMCYAANDTSQRTTTVECHFQSNATKESATAWIDYILNRDACNRYGQDKLNNKLIRDWFMIILSSLQEMNDNSSIQIWRWGCKHSNLSGKGVSGVGVMISSSLSCVDDLGLQGLELELRLTRLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8E2</accession>
    <name>A0AAD8Y8E2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8E2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="195" mass="20876" checksum="D588051786359842" modified="2024-05-29" version="1">MMATASTTTNELATDGKDGQPAPRRRAGGRRGTNTLSSSFKAALSISNDQNSDDPPPESDDAAPKRRTSSRRQQRGGSLGSCLSNSLNRSTNGIERTEGRLSVSFSDNRGLSTATIADILAGSGLDPDEPGSESEKSLKEMMDEQEEAIEGRDSLASLGGSTPLSPRSQRRRRPQLQTIVSQRIMKFDSDGSDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8W5</accession>
    <name>A0AAD8Y8W5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Lipase class 3 family protein</fullName>
            <ecNumber evidence="9">3.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_008442</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8W5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31403">
        <property type="entry name" value="PHOSPHOLIPASE A1-IBETA2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31403:SF7">
        <property type="entry name" value="PHOSPHOLIPASE A1-IGAMMA3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="8">
        <location>
            <begin position="161"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1741190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="419" mass="47660" checksum="3784BAA3F2B8D2F7" modified="2024-05-29" version="1">MGETKFDELISDLVKVSSFVYEFRDLRAVVKKNKQGTIKKRSTGWFSSEEYKVEYVTPAHIITQKGSQQDDKNQHLKYDITLPAIKQFLEENRKWFKLEDGAWKFDESRTEKKEPFPLEKELDVLMEDNLRIIDYDDEFTEGDGGLVYGVAVNLTHKWITVVFRGSVGKTDFLTDRDFNLDYNSFFKTEGNISGGKPGTHAGFTKYLVDEKMGDQDGRKCLDRILACVNNEFETNKDVAGKDFSLYVTGHSLGGGLANLFAFRVAQLKAMNHESVKFLPNKVTALTFAAPVAGNHDYNKEFQSLEKKGILRHIRVANEGDAVPTNEIPLPFSLALAGNSHEYTQNGVNLHLFPDKELAVDYRNTKPFNSQFFYLNPMKSAETHFVAEYIRRVELPANKNSSCYQKTVEEIYAHAGDCTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y982</accession>
    <name>A0AAD8Y982_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lactate racemase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007430</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y982"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048068">
        <property type="entry name" value="LarA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043166">
        <property type="entry name" value="LarA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33171">
        <property type="entry name" value="LAR_N DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33171:SF17">
        <property type="entry name" value="LARA-LIKE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="456"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="489"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="537" mass="59760" checksum="2F79F6D99D198FC9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9E1</accession>
    <name>A0AAD8Y9E1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008433</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9E1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="116"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="326" mass="36207" checksum="78FB6168DD83DF03" modified="2024-05-29" version="1">MITQRRSRRRRRDGDEEAGPHATVHACRRLGCCLHCKYLHDTKAGGTEYGVLLERLSEIGFGVINKAVFVDTSLSLPEAELTQEISKAKQQSMLRLQPIFEAIEQTSEDSSISLQSEEVEQLMASHEEELICLRSELEASFAQVLAKNVKELTSSHMAELERVREEAEQERMANLSHTMTNSSQSKQVAQNVASHQEYAVEIVSIGADLLGLPGGDNGNLSSKEENWTRFIERVEEKRIERSSSIPTSPVLVIGQCDLFSPLIDKLLALSRGEYTVRKIEVATSKLAKILHFRMKAIGEAANAQIGKIEEDHVTVPDLSLAPLSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9J1</accession>
    <name>A0AAD8Y9J1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_007935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9J1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1741457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="252" mass="28834" checksum="3176FC8824910583" modified="2024-05-29" version="1">MSIIAEDRNEEDGKKSYPGLMSFFGGFHTLMKCANCNGEMFANILSTFVASWRNSTKKVEWFTLPSDPKQREAETPQHTAAHYAAAALPLKEKFGSWPSAVEVNNHMMERAEKYPICALVLLFLRSEVILKMLRASEKIGKRGCVELFFYCLKLDVPIFAVTHKTDYMRLVCDLLQWYKCASPADKVIYEHLIYTQVTSLGQSQWSDLFMEKTIGDIRSYAGRTYRRGTSAKIEHACEDIPTREIRVTSWMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9M2</accession>
    <name>A0AAD8Y9M2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mitochondrial carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_007326</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9M2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF10">
        <property type="entry name" value="SLC (SOLUTE CARRIER) HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="17"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="170"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="274"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1741753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="366" mass="39730" checksum="7B047EA7E0B6C9AB" modified="2024-05-29" version="1">MSARMEGDDHSYSYSATTIRNGLISGYTAGICGIVIGHPLDSLKVLLQTANAGPTNPSSASGSGVRVGAKVVNSSNFVISRASSTAAAAAVSTRPSSVQTSNIIPAGKRSLTSLYAGVTGPLLTVGLIQSINFAVYDSVRRVLYERQLRRENDSGVVLVNCLPDDYLHYDDLQNVAVASFISGGATSFLTSPVTMVKTKQQIMQWSFRKAIQDTWSRGNSKLKLQNFYTGFGIHFCCDAFGRSLYMFTYEYLKRSMSERQHVDVDSNSASPANLSIPQRMICAASAGMTCWAFIYPADVIRSRLYSQSLNSQSLPTTMDGIRLAQQMVRETGYQSLYRGMPISVARAGPVAAAILPVYDYMLDMIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9X4</accession>
    <name>A0AAD8Y9X4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006908</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9X4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="3"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="389" mass="43980" checksum="BCB2329AA14D439E" modified="2024-05-29" version="1">MGGGNFDILPEEVLRSILSYMDVPSIGAISATHKPQHKNLASLASDEDTWYMLTQRRFGIGCNHKRRTWRKKKKNVVLVKRGSSSSLSSEASTGVGESRRRRPQTYGGATWKDAFRSLSLAMRIPETSLTSGSAAKSGGAVFASPSNRWWNKRSTVLNDPEPDLFKACNYLGIWCMLNHAENCQTKLCTNSANSRRRRVVSLPYRQDMRYLELKLCLQNTKSGFGTICIPSIDMIRMATLEEDDYFNAWGWDKCDYDYPLTFNMVKHGPWAPKLLLHQCVDSDRTCDIERELDVKDAIVLRPFEVVILSIHIACPFEMSYETDVLSTMSSIRVPVTSYGPLSSNHLGVQQHKHSVATARFLEEDALWEYYSQLPGGCLSLTDRSRLVPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YA24</accession>
    <name>A0AAD8YA24_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007176</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YA24"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="197" mass="21180" checksum="967CC33802FA7A1D" modified="2024-05-29" version="1">MGVFKVINAVVGGGAEVAEPEEPGLTLIDMIVSQMTDVPLDGTSLLFCMAMSLSLCFVVVLAIAPRSGLQHVCEKEESGEQTESEQKDTHEVGELMGKIINTEAEAEQDDTEDETVSKDDSKPYDEPPTPTMSPPPTETIDMKGVDKNSSENIAPSIPDMSMTRMSSRRKGGLTAKAKSIGGSIRRLGLNEYTSKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAS6</accession>
    <name>A0AAD8YAS6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Actin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_007208</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAS6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="351"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1741635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="542" mass="58778" checksum="CF8E08BF135144E9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBH3</accession>
    <name>A0AAD8YBH3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006952</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBH3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="269" mass="28026" checksum="3E597D49407CE4B1" modified="2024-05-29" version="1">METGGSKYSGESAFQSTKVSKTDAVQTGASNYSGDSAFQSTKVSKTDAVLTGASNYSGESAFQSTKVSKTDAVQTGASNYSGDSAFQSVKVAKADAVQTGASNYSGDSAFQSVKVAKADAVQTGASKYSGESAFQARKVTKVDSVQTGSSKYSGESMFTAKKVVKADSVQTGSSKYSGESMFTAKKVAKADSVQTGSSKYSGESMFTAKKVAKADSVQSGTSSYTGGSMFQTKKLPRHHLGRILQEHQVTLETACSQLRRSPNLVASKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBS2</accession>
    <name>A0AAD8YBS2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006475</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBS2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF309">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="397"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="397"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1742878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="657" mass="72372" checksum="AD80CD27B7D391D8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD38</accession>
    <name>A0AAD8YD38_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nascent polypeptide-associated complex subunit alpha-like UBA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006432</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD38"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044034">
        <property type="entry name" value="NAC-like_UBA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19026">
        <property type="entry name" value="UBA_HYPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nascent polypeptide-associated complex subunit alpha-like UBA" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="32" mass="3531" checksum="DCA2E09DC28BD1E9" modified="2024-05-29" version="1">MVMSQAGCNRKRAVKALKDHDSDLIEAIMSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDG7</accession>
    <name>A0AAD8YDG7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sulfotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005857</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDG7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="431" mass="48625" checksum="E82E1D5B2CC37F42" modified="2024-05-29" version="1">MALLTTSSSSSVRRSSSSRLVKLLAVLLFLTLVTIQFSLVARLSKLSELDDPPRLHGGSKHIRHDGNKDTQSADRGAKDNTSLLQDEERLITPSTSDGTLQGKERLWQMLITRNVTQLYASYWNSVPHWDAVTNNIHRTAPIIHGLETCETFQKITSDSPSQRRIAPAGLFNTGTNLLSVLLEYNCQNPHRVEKFNGNAKRGHGNEWQTRWGKHTPARYRRTYSTSKNPKYSVDEVLPIVLVRNPYGWMKSMCRNPYTASWEGRSNSKTCPKLKKGNNQWNEVNVKFGPGQTHHKSLGHLFNDWYGDYFYSNSTKDDGNERNTTAPFPRLIIRFEDIIFFPQEVTEAVCKCAGGTLGHRADDKDVANGTFHYVVRSAKAGFGHGPQSHRNGLIDSWIRYGSVDPQSEYSPHDLALAQEVLDPLIMDAFAYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDT7</accession>
    <name>A0AAD8YDT7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sulfotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005801</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDT7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053259">
        <property type="entry name" value="Golvesin-related_Golgi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32301">
        <property type="entry name" value="COUNTIN RECEPTOR CNR3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32301:SF6">
        <property type="entry name" value="GOLVESIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1035"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1037"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1047"/>
            <end position="1059"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1136" mass="129534" checksum="FD0661B1872883A6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YE71</accession>
    <name>A0AAD8YE71_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YE71"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="164"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="375"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="603"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="204"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="334"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="171"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="383"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="405"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="440"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="453"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="606"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="642"/>
            <end position="653"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="653" mass="73005" checksum="BA1B488F979C1B1C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YE92</accession>
    <name>A0AAD8YE92_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA (guanine(9)-N(1))-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.221</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_006026</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>guanosine(9) in tRNA + S-adenosyl-L-methionine = N(1)-methylguanosine(9) in tRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:43156"/>
            <dbReference type="Rhea" id="RHEA-COMP:10367"/>
            <dbReference type="Rhea" id="RHEA-COMP:10368"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.221"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.221" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YE92"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002939">
        <property type="term" value="P:tRNA N1-guanine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028564">
        <property type="entry name" value="MT_TRM10-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038459">
        <property type="entry name" value="MT_TRM10-typ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007356">
        <property type="entry name" value="tRNA_m1G_MeTrfase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13563">
        <property type="entry name" value="TRNA (GUANINE-9-) METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13563:SF13">
        <property type="entry name" value="TRNA METHYLTRANSFERASE 10 HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51675">
        <property type="entry name" value="SAM_MT_TRM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent MTase TRM10-type" evidence="6">
        <location>
            <begin position="65"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1743405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="300" mass="33949" checksum="0B481AD2F50A359C" modified="2024-05-29" version="1">MDSDAAAADAATDTAAALDRLQISDDANTDDAAELPAASSTLECKPDAASTPIILCDAFYGFPTQKRPRNERVRAVSRQLTNFLQWRSEASEKNSNNIHSHVHVLGKGKDIESVKTRIDELGTQTKASTEQIIFDPDIEIRQFLDKQNGTSSTQESQEEVVYLSPDASYTLPTTCRPPRIVIVGMLIDRRITEDRSRRRAEESLNIRAAKLPLDELRVKELSSCEPLNVDTVMELMQRWWWNCDRVEERLQQINGSGETKCDDNTEKYGKLYKKCFIEAAAYAMKSQRDRHPNRTVHKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YE93</accession>
    <name>A0AAD8YE93_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Bacterial surface antigen (D15) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_004200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YE93"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.310">
        <property type="entry name" value="membrane protein fhac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.50">
        <property type="entry name" value="membrane protein fhac: a member of the omp85/tpsb transporter family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bacterial surface antigen (D15)" evidence="4">
        <location>
            <begin position="428"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="347"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1744909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="646" mass="69227" checksum="EEB971FED8747F2D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEL0</accession>
    <name>A0AAD8YEL0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005403</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEL0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042045213" evidence="1">
        <location>
            <begin position="23"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="221" mass="24002" checksum="4C3887C8405279B3" modified="2024-05-29" version="1">MLKLNCMFLLIAAVAQLPMSCSFLSPSTMNHQIPRQLLAASSSDDFMVTSNHRRTILSGPLIFTAGTILSTVFDNKAALAADGQLSVLLDQIKEGSKQLEAVPDLIKAEKWDAVRAVLVKPPLSNMWTSGGANKLLNKYADAIGSELPDGDEIAALELREDLISHLRYLDMAVYNNVFNPIGSEGTTGATKELIRSYYEDPINEFTASKKAIDDLIGLASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEP8</accession>
    <name>A0AAD8YEP8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WRKY19-like zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005682</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEP8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056866">
        <property type="entry name" value="Znf_WRKY19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24906">
        <property type="entry name" value="Zf_WRKY19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="9"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="463" mass="50001" checksum="84FF2587E5091E83" modified="2024-05-29" version="1">MVTLIRTLKRITTSTSPPTNESSKSKTATVATGTDQNFSANHVHHGQLKKIQTTANDAIEMSKKERTSSDNTTSPQNSSDEKSAAVNSNEKNTETKLDQKRKASTHEELPTKKAAVNKYKKICSTNGCTHVAVQAGVCMRHGARRKLCSSEGCTNAVVGGVCIRHVAKVTRKLCSREECTNQARKGGVCIRHGAQKKRCSSEGCTNQVRQGGVCVRHGAKRKLCSSEGCTNQAISIRGGVCMRHGAQKKLCSSTSSGTATSTAQTAQNISAVKKTETTANDAIEMNKKERASSAVTLRSTSTSSQKPFATADSTSDEESAAADADERNSQTKFDRKRKASTDEDEELPTKKAAVNKYKKICSTNGCTHVAVQGGVCMRHGARRKLCSSEECTNQAIKGGVCMRHGAQVTRKRCSREECTNQAQKGGVCMRHGAQRKLCSREECTNYAKKGGVCMRHRANPWDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YF41</accession>
    <name>A0AAD8YF41_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">inositol-3-phosphate synthase</fullName>
            <ecNumber evidence="5">5.5.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_004328</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:10716"/>
            <dbReference type="ChEBI" id="CHEBI:58401"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="5.5.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Polyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the myo-inositol 1-phosphate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.5.1.4" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YF41"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004512">
        <property type="term" value="F:inositol-3-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006021">
        <property type="term" value="P:inositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002587">
        <property type="entry name" value="Myo-inos-1-P_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013021">
        <property type="entry name" value="Myo-inos-1-P_Synthase_GAPDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11510">
        <property type="entry name" value="MYO-INOSITOL-1 PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01658">
        <property type="entry name" value="Inos-1-P_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07994">
        <property type="entry name" value="NAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015578">
        <property type="entry name" value="Myoinos-ppht_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0398">Inositol biosynthesis</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myo-inositol-1-phosphate synthase GAPDH-like" evidence="7">
        <location>
            <begin position="276"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1745037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="474" mass="51821" checksum="F812D008206C916D" modified="2024-05-29" version="1">MMVQGVTAGILVVGIGGNNGVTLLAGQIANRDKLSWETGPGRVSANWFGCLTQIPPRGVHGGVGFQGRYEGLASADKAAIGGWDIRSTKLGQALYDCRVLEPDLVRQVREEMDGMDIMPGVWDPSFIGESQHETALNVVSGEDNSSTRCRLERIRRDIRMWKEKNNVDGHITVIWSASVERPSEAEYKSADELLEAIYDDSNTDDISPSVLYAAASALEGCSFVNGGSQNTLSAAMTSLFEQSYRQPDAPSTSALSKFAPYSSCPAYCLGTDFKAGQTKFKTAAVEYLRALGLSPRVIASSNHLGNNDMLNLTQKKTLDAKMRVKSDIFGPWQEDDLDHKVSVMYTPYIGDEKRDYVEYTSFGFLSSPHTMVTYTRCMDSILCVPLMVDAAIWCDYFVNHKVSPTDAARATAYLFKVPEGGAKGVDPGFFYQMKELDNVMQKASGKEDDVIAMGLSKGIISEEQANALRALSTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGD2</accession>
    <name>A0AAD8YGD2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGD2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="111"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="164"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="178" mass="19587" checksum="E015BC646785B536" modified="2024-05-29" version="1">MMMTTRPPPGDLLTYAYSLALAESKAKEDAYRRTISINMEPISEEGKPTDDSSSDVASAAITEDSRKELALQRLLKIVDDNKIIIDDRLRRVIAGQDETYTSTDAVESIRRSSSSGSSISSEGRLRRRPSTNKGSLIHRSRRQLGSLFRKSSSRSDGEKESTGDTDSSISSSPTTSHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGI4</accession>
    <name>A0AAD8YGI4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Asparagine synthetase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_004420</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGI4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051857">
        <property type="entry name" value="Asn_synthetase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45937">
        <property type="entry name" value="ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45937:SF1">
        <property type="entry name" value="ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="5">
        <location>
            <begin position="27"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="487"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="551"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="487"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="553"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1745129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="743" mass="81973" checksum="E99D56D7BD99A1DB" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGL3</accession>
    <name>A0AAD8YGL3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_002743</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072380">
        <property type="term" value="C:TRC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006620">
        <property type="term" value="P:post-translational protein targeting to endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047150">
        <property type="entry name" value="SGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45831">
        <property type="entry name" value="LD24721P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45831:SF2">
        <property type="entry name" value="LD24721P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="766"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="837"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="933"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1039"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1216"/>
            <end position="1249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="156"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="683"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="714"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1281"/>
            <end position="1354"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="870"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1011"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1124"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="40"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="67"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="723"/>
            <end position="733"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1746136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1354" mass="149849" checksum="0B32A62125BDA4C1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGZ2</accession>
    <name>A0AAD8YGZ2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Homeobox domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_003016</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGZ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008422">
        <property type="entry name" value="KN_HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050224">
        <property type="entry name" value="TALE_homeobox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11850">
        <property type="entry name" value="HOMEOBOX PROTEIN TRANSCRIPTION FACTORS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05920">
        <property type="entry name" value="Homeobox_KN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 4 7" id="KW-0371">Homeobox</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="6">
        <location>
            <begin position="10"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Homeobox" evidence="6">
        <location>
            <begin position="82"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="4">
        <location>
            <begin position="12"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="4">
        <location>
            <begin position="84"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1746409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="178" mass="20875" checksum="ED106D0237B92679" modified="2024-05-29" version="1">MSSASKPKRKKPDPSAAKLTPEATQHLKDWMLSPEHLDHPYPTEEDKTELMGLTGLSRKQITCWFSNNRKRFWKPKMDELGREANLMGNTLSDHTVDYLKNWMLSPEHIQNPYPTPQEKLQIMADTGIDKKQLICWFSNNRKRIWKVKIQELKELYGVSADANLSDEHWECTRVHLQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHB3</accession>
    <name>A0AAD8YHB3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">5-formyltetrahydrofolate cyclo-ligase</fullName>
            <ecNumber evidence="5 6">6.3.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_003458</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>(6S)-5-formyl-5,6,7,8-tetrahydrofolate + ATP = (6R)-5,10-methenyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10488"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.2" evidence="5 6"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHB3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030272">
        <property type="term" value="F:5-formyltetrahydrofolate cyclo-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009396">
        <property type="term" value="P:folic acid-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002698">
        <property type="entry name" value="FTHF_cligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02727">
        <property type="entry name" value="MTHFS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23407:SF1">
        <property type="entry name" value="5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23407">
        <property type="entry name" value="ATPASE INHIBITOR/5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01812">
        <property type="entry name" value="5-FTHF_cyc-lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00036539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1745534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="300" mass="34099" checksum="5CC852EDAAB640ED" modified="2024-05-29" version="1">MHHTKILLFSSFCNPSLQNFGSSALSRVKINHSKNIRGVHLRPYHYRQSCISFTSTRLHTKISMSDSTKNITDIRKQKQLLRKQIRSRIRSVYPSPSSSTSDDDINAAKMRLTSQSNQVFDQLFKLPQYEAASSIGFFLSMPFGEIQTRDAIQRMVNEDGKTLYVPRVGMNFELCDMDLVRCDSNCDSSNLEGKLFYDNFPTNRWNIPEPPTTNSNVATPGDIDLLIVPGLAFDCNLHRLGQGKGYYDRFIAKMNAATDTEKKMLLVGVCLEEQFLKDGTIPISDHDFIMDMVLTPSEKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHC3</accession>
    <name>A0AAD8YHC3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Serine/threonine-protein kinase</fullName>
            <ecNumber evidence="8">2.7.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_004492</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHC3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF37">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT PRKX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="7">
        <location>
            <begin position="189"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1745201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="243" mass="27221" checksum="46BAF08EB04A2AAA" modified="2024-05-29" version="1">MPCAQAHSLLIVASISINDEALAFSSSISLSYLRTFYLKGKSRGYMHMRLSHILCINSSLHLHHRDGYLKITDFGFSKIVTYKTFTLCGTPEYIAPEVLLNKGHGKGVDWWTLGILIYEMIAGEPPFIAEDDDPIRIYQQVLSGTIRFTRSFDKTAKQLTKKLLTADLTRRLGCLKSGSADIRSSRFFDNMDFDALLAKQLPAPIIPCIKDSTDTSNFDSYPPGCVDDTTPPEFDGEDPFLCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YI13</accession>
    <name>A0AAD8YI13_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Raptor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_002263</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat RAPTOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071230">
        <property type="term" value="P:cellular response to amino acid stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030307">
        <property type="term" value="P:positive regulation of cell growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010506">
        <property type="term" value="P:regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031929">
        <property type="term" value="P:TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004083">
        <property type="entry name" value="Raptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029347">
        <property type="entry name" value="Raptor_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12848">
        <property type="entry name" value="REGULATORY-ASSOCIATED PROTEIN OF MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12848:SF16">
        <property type="entry name" value="REGULATORY-ASSOCIATED PROTEIN OF MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14538">
        <property type="entry name" value="Raptor_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01547">
        <property type="entry name" value="YEAST176DUF"/>
    </dbReference>
    <dbReference type="SMART" id="SM01302">
        <property type="entry name" value="Raptor_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Raptor N-terminal CASPase-like" evidence="6">
        <location>
            <begin position="147"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="1522"/>
            <end position="1565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="544"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="872"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="951"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1113"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="8"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="544"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="560"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="887"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1130"/>
            <end position="1146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1746919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1652" mass="180608" checksum="2F91BE37632A0A3F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YI58</accession>
    <name>A0AAD8YI58_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyltransferase</fullName>
            <ecNumber evidence="1">2.4.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002338</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YI58"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018641">
        <property type="entry name" value="Trfase_1_rSAM/seldom-assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36529:SF1">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36529">
        <property type="entry name" value="SLL1095 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09837">
        <property type="entry name" value="DUF2064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="319" mass="34088" checksum="DFFE558C2DBCAC6A" modified="2024-05-29" version="1">MSASVGGAVCVFAKCPIPGRSKTRIAPLLGEEGAASLATAMLSDILVSLTTCAHLKETLKVLVYAPGSSEGEAHMKSILHSLHLSAISCGEESSRIFDEWVLLPMASGASKEDLTSSSLGSKLEDALDKTRSLLAKVHKMTTTQQSNEAVVFLGMDAPELPLEEIVYGLQTSSGNKAHLCPADDGGYGMLSVPRNAPSSQIFHGIRWSNNSTAVSQLKSLSDCCIDISIGKMMNDCDEPDDVIRLAKRLICSRDSNQDDNRQSKDDVLESLSSSIGSAIRDAETANVCQYTWKALFDLNVITETSDGICLNNSRIASAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YI71</accession>
    <name>A0AAD8YI71_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YI71"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="333"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="376" mass="35407" checksum="C9148ADAEBF5065C" modified="2024-05-29" version="1">MEDTLGIPVGAIDGDAVGCDEGLLDGDEVGGSEGDELGLSVGEPVGWLDGLIEGDAVGEADGIVLGVAEGTVLGVAEGASVGALVGWLDGESEGSDEGSALGAPVGWLEGIAEGSEDTLGEADGWLDGLIEGDAVGKADGDTLGLAEGKVLGDALGEPVGSIDGDALGSDDGLLDGDALGAADGDELGATDGNLVGVELGEADGSRLGEADGDAEGGALGLAEGRAEGDADGSNDGTSLGATDGEADGDADGSDDGDELGAADGDVLGADDGDELGASDGEAEGVALGLLVGVADGVEDGDELGILVGRLDGGAEGAADGELLGTSVGVVLGEADGGADGDADGCEEGDADGNADGDEDGVADGDTDGDELGLLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIS3</accession>
    <name>A0AAD8YIS3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_003759</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIS3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="479"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1745835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="742" mass="84285" checksum="8EDC2F49B20AC4DF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIS6</accession>
    <name>A0AAD8YIS6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein SDA1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_002669</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for 60S pre-ribosomal subunits export to the cytoplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the SDA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIS6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027312">
        <property type="entry name" value="Sda1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007949">
        <property type="entry name" value="SDA1_MD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012977">
        <property type="entry name" value="SDA1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12730">
        <property type="entry name" value="HSDA/SDA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12730:SF0">
        <property type="entry name" value="PROTEIN SDA1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05285">
        <property type="entry name" value="SDA1_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08158">
        <property type="entry name" value="SDA1_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SDA1 N-terminal" evidence="9">
        <location>
            <begin position="118"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="SDA1 middle" evidence="8">
        <location>
            <begin position="599"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="573"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="715"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="772"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="603"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="651"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="717"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="797"/>
            <end position="826"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1746062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="834" mass="92763" checksum="86F37D9A3A0B66AE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIZ6</accession>
    <name>A0AAD8YIZ6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidyl serine alpha-galactosyltransferase</fullName>
            <ecNumber evidence="2">2.4.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIZ6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044845">
        <property type="entry name" value="HPAT/SRGT1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31485">
        <property type="entry name" value="PEPTIDYL SERINE ALPHA-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31485:SF7">
        <property type="entry name" value="PEPTIDYL SERINE ALPHA-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="922" mass="102453" checksum="C1D492995DA806E5" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJF7</accession>
    <name>A0AAD8YJF7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CobW/HypB/UreG nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJF7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW/HypB/UreG nucleotide-binding" evidence="1">
        <location>
            <begin position="4"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="57" mass="6020" checksum="B307DA74D8CE60F1" modified="2024-05-29" version="1">MAEGVVELQNGCACCSLADELLTSVERLTEGGRELDAIELSGVADPVAVRDNWDKIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YK62</accession>
    <name>A0AAD8YK62_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sel1-like repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_000028</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YK62"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="8">
        <location>
            <begin position="17"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="155"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="8">
        <location>
            <begin position="300"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="365"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="437"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="634"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1748089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="817" mass="92631" checksum="0B2401AFDCEC466B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YL51</accession>
    <name>A0AAD8YL51_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phytochelatin synthase</fullName>
            <ecNumber evidence="2">2.3.2.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.15" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YL51"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016756">
        <property type="term" value="F:glutathione gamma-glutamylcysteinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046938">
        <property type="term" value="P:phytochelatin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010038">
        <property type="term" value="P:response to metal ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.30">
        <property type="entry name" value="Phytochelatin synthase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007719">
        <property type="entry name" value="PCS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038156">
        <property type="entry name" value="PCS_N_sf"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51443">
        <property type="entry name" value="PCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Peptidase C83" evidence="1">
        <location>
            <begin position="37"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="146" mass="16448" checksum="ECB00FC846C8175B" modified="2024-05-29" version="1">MGRLAAYISNRRIELLSESSPFGAFLMGASSSSSSSNNNKHLLYLMHPTAVTLLYDTSKSSNVMISEYSLDYFLLNSGGFDAQINQAYCGVATVSALLNSLKYMKRFRDVDDISGWTFDLPVDQRYDPYPYATQKIFSWEIVFVTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLN0</accession>
    <name>A0AAD8YLN0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GMP synthase [glutamine-hydrolyzing]</fullName>
            <ecNumber evidence="2">6.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">GMP synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Glutamine amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">QTG54_000853</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the conversion of xanthine monophosphate (XMP) to GMP in the presence of glutamine and ATP through an adenyl-XMP intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>XMP + L-glutamine + ATP + H2O = GMP + L-glutamate + AMP + diphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.2" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLN0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003921">
        <property type="term" value="F:GMP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01742">
        <property type="entry name" value="GATase1_GMP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01997">
        <property type="entry name" value="GMP_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.10:FF:000002">
        <property type="entry name" value="GMP synthase [glutamine-hydrolyzing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000001">
        <property type="entry name" value="GMP synthase [glutamine-hydrolyzing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000001">
        <property type="entry name" value="GMP synthase [glutamine-hydrolyzing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00344">
        <property type="entry name" value="GMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001674">
        <property type="entry name" value="GMP_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004739">
        <property type="entry name" value="GMP_synth_GATase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022955">
        <property type="entry name" value="GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025777">
        <property type="entry name" value="GMPS_ATP_PPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00884">
        <property type="entry name" value="guaA_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00888">
        <property type="entry name" value="guaA_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000848">
        <property type="entry name" value="PRK00074.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11922:SF2">
        <property type="entry name" value="GMP SYNTHASE [GLUTAMINE-HYDROLYZING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11922">
        <property type="entry name" value="GMP SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00958">
        <property type="entry name" value="GMP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00097">
        <property type="entry name" value="ANTSNTHASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00096">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54810">
        <property type="entry name" value="GMP synthetase C-terminal dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51553">
        <property type="entry name" value="GMPS_ATP_PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="6 14" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="4 16" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 14" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMPS ATP-PPase" evidence="15">
        <location>
            <begin position="282"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="310"/>
            <end position="316"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1748914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="603" mass="66773" checksum="AFDCD79124435B7F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMR0</accession>
    <name>A0AAD8YMR0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000787</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMR0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="443" mass="47758" checksum="ED594EB35A1F09F7" modified="2024-05-29" version="1">MVSFRKKKSSKAAGKAGADDVATPKGGAPPQADDSRDEQPAIPSRPPTMDDIPDLLATMEKEKGEKAANATKRVYELCDVGHKQNRVPMVCSGQYDVLTPLANCLTQESGDGRHLACLALNNLSIPTENKRVMALGPSSAAVIGGLCKVIAEDKQESYLCCICLMNLSFLEASITTMLQHSPVPEGASPVAPLDNPESLIRILEKLLKNAPAVPKSGSGKSEGVRWACGLIKNLAKSEENAAMLGKTDIPKCVVENVRNSQTPPSRWTSNSLEDFSLFVILNLAQWPVSKESLVDAGAVDVVKPIMAEGDLQGLKATMACSFLGASWGDFPETGSAAAKSISELMTNIIEKKGRMDNTLMESSSCTLLPKLTVILVMLQLKTRPVPRFSLFHPQLLSASRLCLTSLWLPTMKPMVDQNTCLMSSQPNIRWCHLQHASCHPPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YN80</accession>
    <name>A0AAD8YN80_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Gamma-soluble NSF attachment protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">N-ethylmaleimide-sensitive factor attachment protein gamma</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_000503</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YN80"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005483">
        <property type="term" value="F:soluble NSF attachment protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000744">
        <property type="entry name" value="NSF_attach"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13768:SF2">
        <property type="entry name" value="GAMMA-SOLUBLE NSF ATTACHMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13768">
        <property type="entry name" value="SOLUBLE NSF ATTACHMENT PROTEIN SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14938">
        <property type="entry name" value="SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="468"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="509"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00042485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1748564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="523" mass="55976" checksum="370E07597B60A26D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D369</accession>
    <name>A0AAD9D369_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_017098</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="mitochondrion" evidence="1"/>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000083">
        <property type="protein sequence ID" value="KAK1732057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D369"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1732057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="67" mass="7836" checksum="131F5CCF44DC604C" modified="2024-05-29" version="1">MVEGFQIKFVKNLVSLSTSESTHILELICFLRLRYQKHLYSVGKLQFSDYEPLTDKQVDLILDSKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D401</accession>
    <name>A0AAD9D401_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ankyrin repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_017019</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000076">
        <property type="protein sequence ID" value="KAK1732284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D401"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052420">
        <property type="entry name" value="Espin/Espin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153">
        <property type="entry name" value="ESPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153:SF8">
        <property type="entry name" value="FORKED, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="230" mass="25419" checksum="351EBDD90AEE0929" modified="2024-05-29" version="1">MTLSINKLMNYVAIVLDLIHCQEWAALEKVATEHKLFKVISEHIQKCDEFNGMTLLHAVVKYNPSLHILDAMIDAHGDALMGQDCVGRTPLHVACGTGASAEIIRRLVKAYPQACDLQDEDGRLPLHIACDIECVLFEGDQTERAPPTIDVVRALLSGSLRSVLVEDEDEMSPIEYAIVSDANINVVKLLQKASMTLRRKEVQASKATARSYAAEIRPIVPLPRSVLSYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4S3</accession>
    <name>A0AAD9D4S3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015279</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1734021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4S3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="131"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="478"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="536"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="75"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="610" mass="68544" checksum="59C417D4E2F3B868" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5H1</accession>
    <name>A0AAD9D5H1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aldo-keto reductase family protein</fullName>
            <ecNumber evidence="4">1.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_014674</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5H1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="3">
        <location>
            <begin position="19"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="353"/>
            <end position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1734801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="646" mass="73729" checksum="434534646962688A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5L7</accession>
    <name>A0AAD9D5L7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SET domain-containing protein</fullName>
            <ecNumber evidence="3">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015386</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5L7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF137">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042181402" evidence="1">
        <location>
            <begin position="27"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="75"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="453" mass="50936" checksum="078C3BAEB7AA6B8C" modified="2024-05-29" version="1">MISMSTRCVPLLSVLLLLLAFRNGVSFLLPSASSLLTTSSKSRADVTNTLLNYSQQRDVYTMEAWAIENGYQKVDGVELYSEGDDDWSMMTNTDIPAGTTIMFIPSTLVLSSDAIVKEYGSNFDLELTENALKQMERDLAKRLPLFRLLVKILAEYEKGENSFYAPWINSFPTQYYNGVSMTDACFACLPPYAALLSMNERNAYSRFLNAIRKGFLPLNPDVTGDDSVMKFAYNVALTRFHEVFEPTRQKLIAPMADMINHSSDPNAEISFDTENNCYVTAIADIYAGSPLSVSLGDPTDPTPLFAKYGFLPTGCNTIFCKAIHLEPQINELGYEFNQLLFQTDTGEVYPAVWDIFLLKILQDYDADLASQFTMACQNNDEATKETFHSNYFAYTLEALREHVYSILNDVDQMTMEAQSYDLETHPRVPVIVDHNNLVRDTFSMTASLLDSMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D906</accession>
    <name>A0AAD9D906_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012147</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D906"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="175" mass="19055" checksum="E56C85325D35385D" modified="2024-05-29" version="1">MSTMSQAQPRHGARRAFGSIINTNSTPRKAAKGGASAITDEVHSAKKEKQASLFSMATRSSKKRAASLKEAEDKEVSAVESPSKKTATKNAVLPKAAKSLFKEEVVGEEYLGAREVFRTLPEVDAAFWDEMEDLLEIKLANPIGSEDEFDVNGQDDNEDKQPANLKEEEEVAGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D927</accession>
    <name>A0AAD9D927_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012207</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D927"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="70" mass="7540" checksum="A9023714C473CEAD" modified="2024-05-29" version="1">MTTPPPASSSKNPFSSGLGRGGRMGAWAVAIGAVAAWNYYDNQKNTADAFSKEEQESWNTQKKTASTKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9V3</accession>
    <name>A0AAD9D9V3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011294</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9V3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277">
        <property type="entry name" value="ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277:SF81">
        <property type="entry name" value="PROTEIN ABHD13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="2">
        <location>
            <begin position="95"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="359"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="460"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="482"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="508"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="527"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="544" mass="60955" checksum="D554F596B4784C03" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAM4</accession>
    <name>A0AAD9DAM4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fascin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009272</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAM4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008999">
        <property type="entry name" value="Actin-crosslinking"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50405">
        <property type="entry name" value="Actin-crosslinking proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="536"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="567"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="629" mass="68761" checksum="0F4307A2A5FDBBDE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAN2</accession>
    <name>A0AAD9DAN2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010808</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAN2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042179767" evidence="2">
        <location>
            <begin position="16"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="456"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="468"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="517" mass="53207" checksum="CD1DD4DDC32808A3" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAQ9</accession>
    <name>A0AAD9DAQ9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cysteine oxygenase/2-aminoethanethiol dioxygenase family protein</fullName>
            <ecNumber evidence="4">1.13.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_008656</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAQ9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012864">
        <property type="entry name" value="PCO/ADO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22966">
        <property type="entry name" value="2-AMINOETHANETHIOL DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22966:SF61">
        <property type="entry name" value="2-AMINOETHANETHIOL DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07847">
        <property type="entry name" value="PCO_ADO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1740561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="354" mass="38852" checksum="2F8CC390FDBE2C2A" modified="2024-05-29" version="1">MCVSTMANDGGLRKVFQSADLVYNQLLILDQHKLHDNSNIAAGDKRKPSRSLSEVSSSSIIKSPKINLSQHSSASLRRAVTPLIQSMEQLDAAALLSLNPNQDGNGAVLDPKKGSSVPPIHDRIVPYHRFHRAENTVRYLHAREVADKYTVGIFIFPPGASIPLHDHPSMVVISRVLYGELKVKSYSVVSSVHDDDVVEEMKEETSGTKCDSSPSRIRSSINRIKDFVSRAVLSSHHDHHAATQHKLQVQVNKSPLGVQFSSDGDGESSAIISAPNVTALYPDEGNCHSFVAGPYGAAVLDVLLPPYAEDEHRDCTFYEAVENEHGYCLTPIDQPSDFDCLSGEYGRFNSCDQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAW5</accession>
    <name>A0AAD9DAW5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Replication factor C subunit 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_008851</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the activator 1 small subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAW5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000030">
        <property type="entry name" value="replication factor C subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.272.10:FF:000002">
        <property type="entry name" value="Replication factor C subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000136">
        <property type="entry name" value="Replication factor C subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050238">
        <property type="entry name" value="DNA_Rep/Repair_Clamp_Loader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669">
        <property type="entry name" value="REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669:SF1">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13177">
        <property type="entry name" value="DNA_pol3_delta2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21960">
        <property type="entry name" value="RCF1-5-like_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22534">
        <property type="entry name" value="RFC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1740756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="376" mass="42424" checksum="ECC6FAFB120860F6" modified="2024-05-29" version="1">MLWVDKHRPSRLSQLTYHTTLTQRLESLAADPGGLPHLLFYGPPGAGKKTRIMSLLRQVFGPGAERLRLDKRTFTTPTKRTVDINMITSNYHIEMAPGDAGLNDRFVIQDVIKEMASSKNIATVGMYKEKSGTNDDDTAKNTKKKADYKVVVLVEVDKLTRQAQAALRRTMEKYSASCRLILCCNNPSKVIDPVRSRCLGIRVAAPNVDEIAAVLKVVARKESISLPDELAINISRESNRNLRRALLMLESCHVTARDESPNALKATQPVPHTDWERYISQLAKEIVKEQSPQRLMATREKLYELLINCIPAQVILKTLVMELLNSLDDSIKGEVITWAAFYEHRISLGSKEIFHLEAFIAKFMAIYKKYLADLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCZ5</accession>
    <name>A0AAD9DCZ5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">U3 small nucleolar RNA-associated protein 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_008447</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UTP11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCZ5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007144">
        <property type="entry name" value="SSU_processome_Utp11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12838">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12838:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03998">
        <property type="entry name" value="Utp11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="140"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="315"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="140"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="238"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1741195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="342" mass="40082" checksum="149AF2C066AFFB9A" modified="2024-05-29" version="1">MSSLRNAVKRITHKERSQPQSRSHLGLLEKKGDYRQRSRDYHRKQDRLKSMRDKIANKNPDEFYFGMHNSRVDNYGLRKGGSSGRHVKTDEARQKELEEKGLGADAVRIMKDQDLAYVRMQRVMDGKKVERLQSSLHYLEGNHRQYNRDDNDGHVDNSEDDEEESGALLKMVAKKRKHTVFVDGGQSAVDNFDAARHFDTIPELVGRSFNRPRVKELEREAMRRLGGTVAVRDADDDYYYDDDEDEDDNFDEEGNPKQVQLTEKQLVKQERNQMKLEKRIAKSRSAAYSEMELRNERMKKLQNAEAHLIVEKQTRMKGRKRKIAGKEDGKPAVYKWRRKRAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDC3</accession>
    <name>A0AAD9DDC3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_005778</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDC3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051068">
        <property type="entry name" value="MFS_Domain-Containing_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23510">
        <property type="entry name" value="INNER MEMBRANE TRANSPORT PROTEIN YAJR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23510:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042148893" evidence="7">
        <location>
            <begin position="21"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="414"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="8"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1743157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="547" mass="60665" checksum="5C492D8E91729BAD" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDI8</accession>
    <name>A0AAD9DDI8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sulfite exporter TauE/SafE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_005973</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDI8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031464">
        <property type="term" value="C:Cul4A-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14255">
        <property type="entry name" value="CEREBLON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14255:SF3">
        <property type="entry name" value="SULFITE EXPORTER TAUE_SAFE FAMILY PROTEIN 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041900557" evidence="6">
        <location>
            <begin position="22"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="90"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="191"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="419"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1743352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="499" mass="54485" checksum="5747E7233EA03538" modified="2024-05-29" version="1">MPPRIIHIIALAALLISSAAAFEWLDLVSESSDRVNDASTSRIFTILNSLTSSPETQPLLFDQQHANSTDFVNNHPSDHAPLFPLKAEDFIGFFLAALGLILAAGGGIGGGGILVPIYILVLGFMPKHAIPLSNVTVFGGAIANTIRNVRQRHPTADRPLIDWDLILVMEPSTLAGALIGANLNKVLSETAIAVMLVILLTFTAYNTLKKAMKLYKKESVELMKKSIGTRTVSPSTVIKDDSDALLDLNQYLLLNDSLEEFEPSDHLGASGDFTAGELSMQEVTNFGTGPPSPISVQNGYDDYYYNDKEDDFPEHVDPFQLQQILDEERHPKRTKIALIVTMFLVVLTINILKGGGGFQPLGIECGSAAFWVAQVVLLLWIFMIAFIARKTLIKDTKRRIDAGYSYLPEDVRWDERSTVVYPLISTLAGLCGGLFGVGGGIIKGPLMFFILGTLLHFLSTLQEYKSISVVVSDDFFTSHASSNRRVIIFALGVATLLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDQ5</accession>
    <name>A0AAD9DDQ5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDQ5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="296" mass="34072" checksum="C815F6D6046CEE4A" modified="2024-05-29" version="1">MKYNDYYWDELPMEAKAAAANLGFTQEIWDSNQESTCCKEEWDELTEVQQYAATLLGYNQKMWDNMAMYLLNLRFSVLCFLLGSIFYFRLSFLDLVWVKYVRDHVPEILADEDDDEIWIQWAAEHNAADVLEVRDDYYEQYELFHKLGVTAFVVMGFSAVCRERSRASLILLVAGLAGMAGAHSSTDQIAAYWSCISVHLFLMSCYNLDSKLFFAGCILECMLSYLLLAGYMGLWIAYADMIASLLWLYCALQEVPAVFEFGFSSGKDGHSTHREVFIEMMYSLISLPPNFKVKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEA0</accession>
    <name>A0AAD9DEA0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA photo-lyase FAD-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_007078</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="4">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA photolyase class-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEA0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003904">
        <property type="term" value="F:deoxyribodipyrimidine photo-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032922">
        <property type="term" value="P:circadian regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043153">
        <property type="term" value="P:entrainment of circadian clock by photoperiod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.579.10">
        <property type="entry name" value="DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="CRYPTOCHROME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455:SF18">
        <property type="entry name" value="SI:CH1073-390K14.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="Cryptochrome/photolyase FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="Cryptochrome/photolyase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0274">FAD</keyword>
    <keyword evidence="2 4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cryptochrome/DNA photolyase FAD-binding" evidence="6">
        <location>
            <begin position="198"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="421"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="421"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="473"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602081-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1742513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="492" mass="56291" checksum="B526E7FE25562175" modified="2024-05-29" version="1">MSNNHRQRQAPRSTLSVYHTLSVRARSTERETVHGSHVAFVNEGLVDLDLRLSSGNSEPTATNSDIQGDIYEHKFQCITVCRAGAAFTLRSIHKQRPINQILCHMESSHLKSFARDKAVRRWCRHEQIPIKEMNQTGVTRCLSDRDDFRKTLTSSWDNRYMQRQQKCIITKQKQEELRAAKKKAPSTPSPWLRSLASFQSRMHWRSHFIQKLESQPSLEKQDQCLAFSHLRRQPDDFNEKYFEAWCQGRTGFPFVDACMRSLIHTGWLNFRMRAMLVSFATYNLWLDWKKIAGHLARLFLDYEPGIHYPQLQMQAGTTGINAMRVYNVTKQGKDQDPSGVFIKKYVPELATVPDEYIHEPHKMPASLQKKCGVVIGDGKGGNEKKSIEIFQTQQSTTILSTKECICYPSPIVDEKITAKSSKDKLSAVRKQDSTKREAEQVYLKHGSRRTNGDRDGAKPKALNSASKRVKVDSAQQSLMKSWSQSQNGGGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEJ3</accession>
    <name>A0AAD9DEJ3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phospholipase/carboxylesterase family protein</fullName>
            <ecNumber evidence="5">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_005870</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEJ3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008474">
        <property type="term" value="F:palmitoyl-(protein) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050565">
        <property type="entry name" value="LYPA1-2/EST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655:SF17">
        <property type="entry name" value="LYSOPHOSPHOLIPASE-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655">
        <property type="entry name" value="LYSOPHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
        <property type="entry name" value="Abhydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042139842" evidence="3">
        <location>
            <begin position="22"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipase/carboxylesterase/thioesterase" evidence="4">
        <location>
            <begin position="39"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1743249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="286" mass="31501" checksum="0604810275EFFCB8" modified="2024-05-29" version="1">MTMMKLPVVVCLLAASSLASAFQSHDVGNRWTPPSSGDDRGAVVFLHGMGDTANGGWAALDHMLPSICPRLSTDKIEYIFPQAPVKGITLNGGELVPAWFDLFDFPVDSTSRDDVIGQLNAVCMLEDTVKSIEQERGIPASRIVVGGFAQGGAVAMLASYFRKERKHQPFAGCICLSGWLPNSWNFPVNSYVAEMTPLLWAHGAYDNKVLFMQQAIGTQRLMKEGIDVTVRTYPCAHESYNSQEINDMAEFVDELLFPKVPKQVATAEFVASVKYLFDHNTDQYNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEL1</accession>
    <name>A0AAD9DEL1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA-directed RNA polymerase II subunit RPB2</fullName>
            <ecNumber evidence="2">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_005930</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEL1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1070.20:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1100.10:FF:000003">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1110.10:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1070.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="entry name" value="RNA polymerase Rpb2, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007646">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007647">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007175">
        <property type="entry name" value="PRK09606.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04566">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04567">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 14" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA polymerase beta subunit protrusion" evidence="10">
        <location>
            <begin position="67"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="9">
        <location>
            <begin position="254"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="11">
        <location>
            <begin position="516"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="12">
        <location>
            <begin position="617"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="13">
        <location>
            <begin position="704"/>
            <end position="752"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1743309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="827" mass="93434" checksum="B579391809C6266F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEX0</accession>
    <name>A0AAD9DEX0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NEDD8-activating enzyme E1 regulatory subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005856</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEX0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019781">
        <property type="term" value="F:NEDD8 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045116">
        <property type="term" value="P:protein neddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF29">
        <property type="entry name" value="NEDD8-ACTIVATING ENZYME E1 REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1743235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="667" mass="73661" checksum="B6C1C8F6CC4C3EAA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFH8</accession>
    <name>A0AAD9DFH8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_003720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFH8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1745796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="406" mass="46756" checksum="7B027FF26F158627" modified="2024-05-29" version="1">MALNWKDIHLANEYIYDERLAKHRERGWDFSHLDHIIKTLLFQMPNLANHDLYLYGSVESANDSSRPGSRVGDQIPFFVVISLPTGRVPTRTVGRTNNHTSQMRVISFDDMSYDWAPATDPSYGGRLFYLVCNADYSAVPDDEYEARNHEFSSLFVVTPQDFATDDEGEYRVNYVSFSFLNQDGEEETTAWNLSEHPSLPDYLDQKVDECFAFEDVEDVEEEEKVRVRERIEEAVQTEIRKIRATQEERLNLFFGDLTWNQDSLGDLNVFKITPVNYSATIIPNLDRYFDDLVRQQVGSGERVVYSNHASVTGYELFRRLPPNNSLPGFNTELTPSSPAALFYSCLLVDFLHTTRYIDNLTGLSFDTPVIFDRILETFGIARVLQYFGQDTISGAYSFSRATFFLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFR6</accession>
    <name>A0AAD9DFR6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">E3 ubiquitin-protein ligase, Topors family</fullName>
            <ecNumber evidence="7">2.3.2.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_005087</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
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    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="RNF141-like"/>
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    </dbReference>
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        <property type="entry name" value="Znf_RING-type_Topors"/>
    </dbReference>
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        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
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        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
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        <property type="entry name" value="RING FINGER PROTEIN 141-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
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    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
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    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
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            <begin position="746"/>
            <end position="787"/>
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        <location>
            <begin position="25"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="100"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
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            <begin position="277"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
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            <begin position="350"/>
            <end position="407"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
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    <feature type="region of interest" description="Disordered" evidence="5">
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            <begin position="576"/>
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    <feature type="region of interest" description="Disordered" evidence="5">
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            <begin position="611"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
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            <begin position="698"/>
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    <feature type="region of interest" description="Disordered" evidence="5">
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            <begin position="799"/>
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        <location>
            <begin position="870"/>
            <end position="911"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1744554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1065" mass="114804" checksum="7533EFEE8C96601A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGZ0</accession>
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        <recommendedName>
            <fullName evidence="2">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="3" type="ORF">QTG54_003364</name>
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    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
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            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
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                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
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                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
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    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        <property type="protein sequence ID" value="KAK1745440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
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        <property type="entry name" value="Rad60/SUMO-like_dom"/>
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    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
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        <property type="match status" value="1"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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            <end position="142"/>
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        <source>
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        <source>
            <dbReference type="PROSITE" id="PS50053"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAK1745440.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHE3</accession>
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        <recommendedName>
            <fullName evidence="4">Sulfotransferase domain-containing protein</fullName>
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                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
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                <person name="Godhe A."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
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    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        <property type="protein sequence ID" value="KAK1747896.1"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Golvesin-related_Golgi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32301">
        <property type="entry name" value="COUNTIN RECEPTOR CNR3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32301:SF6">
        <property type="entry name" value="GOLVESIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="449"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="570"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="628"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="726"/>
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    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <end position="260"/>
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    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
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    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="707"/>
            <end position="719"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1038" mass="117626" checksum="51073A72B9D6A0EC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHU3</accession>
    <name>A0AAD9DHU3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_002887</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHU3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044669">
        <property type="entry name" value="YneE/VCCN1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281">
        <property type="entry name" value="UPF0187 PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281:SF19">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION CHANNEL-FORMING PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25539">
        <property type="entry name" value="Bestrophin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1746280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="163" mass="18454" checksum="D7EBD49A8DEFFAE0" modified="2024-05-29" version="1" fragment="single">MLSLLLPGRVRPNYVAVGYIHDEVEEGKKLIMRGVLFEKELEVMASEPGWQPYYCLDVMRCVFTDFMQTSESRLYPEQLKSMEDSIRDMAISIGGLIRLKNTGLPTAYDSFYQTAGIIFLVMASFAWSPEMGWYTPPTAGVITLVFLLMTKIGELMVDPFGND</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJ49</accession>
    <name>A0AAD9DJ49_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJ49"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="225" mass="24875" checksum="E20FBE855615FAD4" modified="2024-05-29" version="1">MLKKLQFKKQGSISKEKSLTVDTTHEIRTSSRRSPAAGMKNKRKDQSKSPRKTAIRPSSSTSRRSSSTASTAASTAASSFASTAPRNTNELNKLLASQILDTSDQSEDGSDVTTGPVDDMLFVLGEAINKGANEVEDFVETKIDSFKDSWDRFTIGLSFRFSDNSTIASDFSEEFEPVKLVKEKGIALEIIDEDSESEVSEKRAVTDEIKNQVQSIIDTYFLYEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJL8</accession>
    <name>A0AAD9DJL8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000498</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJL8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042052723" evidence="2">
        <location>
            <begin position="26"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="621" mass="68723" checksum="85472FCCEFF4A569" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DK28</accession>
    <name>A0AAD9DK28_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ferredoxin-dependent bilin reductase</fullName>
            <ecNumber evidence="4">1.3.7.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_000589</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HY2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.7.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DK28"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016636">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010024">
        <property type="term" value="P:phytochromobilin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1500.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009249">
        <property type="entry name" value="Ferredoxin-dep_bilin_Rdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34557">
        <property type="entry name" value="PHYTOCHROMOBILIN:FERREDOXIN OXIDOREDUCTASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34557:SF1">
        <property type="entry name" value="PHYTOCHROMOBILIN:FERREDOXIN OXIDOREDUCTASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05996">
        <property type="entry name" value="Fe_bilin_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042069056" evidence="3">
        <location>
            <begin position="31"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1748650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="356" mass="39924" checksum="27C8C4118A100925" modified="2024-05-29" version="1">MMPSITMAAALMSAALLLLPAHSFAPPTSSLCYRSKVSPQLQQLKPKKSSYTTSLHLYNKFHEYAWEKLHYNDESSYASTVPDNLKTNKSPVKGSDNNVVACIRSMSEFRKSNTTSNNNVEALRLVRSAFLETQTDSSEALKSPMAIHVLNFVMFPTTHIRDASSGAPVGLPIFGADIVSLPGNKHLVALDFQPVLPINNDDESSANMFPEQYSHLESKLLAIHAKYQKGSDEATEPLLAWGGDIPPQALRWFSPYALWTRLSDENAIQTVSTTVWDAYREYVDLYFELMDAVQEDLDDGKLEIIPGDEKNNAVLSGQREYLEYRRINDPARPMLQRLYGKDWAEELIDGVLFPTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRM5</accession>
    <name>A0AAD8XRM5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_017179</name>
        <name evidence="3" type="ORF">QTG54_017254</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="2"/>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRM5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0934">Plastid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="320" mass="37217" checksum="0262C050260FB656" modified="2024-05-29" version="1">MVFNNRIKEVQKLAYDGFSIVFNSIAKFLGYPDVPGMPIFPLDSKSREQFTVQDLLPKHITEIPPNQAQRPETLTEALFGTFPYTMPIEKHFYQHKAEGYYNFYVENYRNMYFLPDWLSGYIQIHFNITVDHSNLELCRDVFFYVVLLYGAIVSLRTMLFWMLAINPYTYPWVFAVDFVDWIYDGLAGILPCIVGIDLVPTFLGMLIGKIADSVNHLVFTMPFLPSEGNKVKMLIDGELKDVVQFHYLPYLWYKYSIPLNLREFWYAERPDILNFMEKNYGQFGINFQPLLSGSEVSPILDSTGLTDSIIIHSKDFFGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSG2</accession>
    <name>A0AAD8XSG2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000055">
        <property type="protein sequence ID" value="KAK1732999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSG2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="342" mass="37739" checksum="CE7B157B8561F5E2" modified="2024-05-29" version="1">MITTKTKSTGDLMPSSSMSTITSSVHSIKSNAATRRQHIRNGGSGGNSLRSRPIKHHRQRPPLNPIHKTSNNNNLKREYKIRESQTLLLLITTTISFLLFLLFTLPFYALVGLTMMTTFLGLGIVVATSALKTRYLLELEHPLGLLRYLPQKVRVPLTEKSLHDCLISPSTSLNSLKSLDRGSGGGGSGNNSNNSSKNSLSSMLNNKGNNGSNHSSMESLASYNNNSSKKNSSSLSSLSYPRRSSSRPSLLPPPPPPPDRDEDDDDIKPNHTSEFTCSGFDVMRQATVKMGNKTVANQSISQQPKQHQDEKENGDNDKRKREEGGIKSDRYSIYQTNQQVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSI5</accession>
    <name>A0AAD8XSI5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sulfotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016592</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000060">
        <property type="protein sequence ID" value="KAK1732693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSI5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="429" mass="48924" checksum="796359573A0BA4E8" modified="2024-05-29" version="1">MRSAGFLKDKRELLSTYTTHVSPLCTTDTAAPHKQSNVLLDGRLHDAANSAVSTTISSRAMKFLLFLLTILLLAVPYGREILHELGTDNMITKTINARHIRPNLLLSVDTGPYPQRIAPLDPTDKFSFVHISKCAGSTWIRLFKEVLKLNICPEKEDGVEHSVSYQQKYKCKGADYTLISLRSPRHHVWSQFTMCKYSRWGKRVTRKSDDFPRSGDEYEDDEVDFDSWLDNFVSMGNATDNHYNCYHPANFQTRALTSPLDDVHDGRGGFNPNMTLAMNTYKNLDFVALVEFVHESQCMLYYRLGDKAPPTAISYLDKSCHCEKQHEEHQKSKTVYVQHHNMGKRSNLRDLPAATLSKVATLTSADSFMYVNALKNFMDEMAWLESDDGLGRRVVCDNVLKKWESELAYLDGGRFNVTQLYHDAVVEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XT43</accession>
    <name>A0AAD8XT43_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000050">
        <property type="protein sequence ID" value="KAK1733356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XT43"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="87" mass="9491" checksum="1A7D0719115CD53C" modified="2024-05-29" version="1">MLLCHLFCPPSADLDLVGPTVQSCSVCCFFFFLPAAAALLLLDLLLLLLSFEVTRASVEPAVLVVRLDRSILYSFAVIAAFICCLCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTB4</accession>
    <name>A0AAD8XTB4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015879</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000049">
        <property type="protein sequence ID" value="KAK1733464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTB4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013584">
        <property type="entry name" value="RAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08373">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00952">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51286">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RAP" evidence="1">
        <location>
            <begin position="116"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="203" mass="22564" checksum="897A8AFECD98FFC9" modified="2024-05-29" version="1">MGITDTQLFLSFVPTAAKLIDSYNNQALANIAWAYTVADVDAPTLFNLRQNSNPGLPIELLDRSYNAFTSEEPTVSKLQCDVVSQLSSIGLNPQEEVLMGSGYRIDAIVEVNGKIVGVEVDGPSHFIDEGRSPTGSTILKRRQVCSVDGIELVSVPYWEWNKLLGKDEVKRQEYLQKLLGYHTQAINKMQDNDPDFIELEDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUN5</accession>
    <name>A0AAD8XUN5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heat shock factor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_015214</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUN5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF206">
        <property type="entry name" value="HSF-TYPE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="6">
        <location>
            <begin position="28"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1734211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="321" mass="35390" checksum="0CC5BB36EC3D1922" modified="2024-05-29" version="1">MAIRSPASEEGMHSSKKAASSSTSPRRSKSEFPIKLYAMLELADNIPVFARAVTWLPHGRAFKVLDEDTFMEEVVPMFFNQTKIRSFNRQIGRGNEKVWFNDNFLRGVPASMAHLIRTKIKGNTVGSIDDGTIPNFDDMPPLPICDKHPSDVLNEIENAILKIHSSSIAHRDLTMSTLSHASFNDVTDHPTVSLGSSESPCEFSVDVDTDEPFMSPPSLLPAASNGSQGQGVTFMRFHLPLQASTSESMPYTNQTSVEGSSHQAQSHVMLQADFNDVCFSPLKHSNDDFEPLPFWVDNDSCVSDDFANFIGGAIQNVDFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUQ9</accession>
    <name>A0AAD8XUQ9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RED-like protein N-terminal region-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_015566</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000045">
        <property type="protein sequence ID" value="KAK1733711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUQ9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039896">
        <property type="entry name" value="Red-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012916">
        <property type="entry name" value="RED_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12765">
        <property type="entry name" value="RED PROTEIN IK FACTOR CYTOKINE IK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07808">
        <property type="entry name" value="RED_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RED-like N-terminal" evidence="4">
        <location>
            <begin position="79"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="25"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="56"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="96"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="114"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="248"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1733711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="399" mass="44925" checksum="BB383A7D4F55D88D" modified="2024-05-29" version="1" fragment="single">MDNNAFRTLVNQQLKSTKEIAREAVESEFRQKKQKRGGGRRSRVEYDSDSASDDDDLKRRREGDKKSGEEVSDEPEWKRRRKEKAAATTGGGGQQWRDRAKERREGKNLDYNDAVTTATIHSSSINGGGDEYTDKKRQAELSKFLGGDEEHTHLVKGLDLALAQKVRREEMGAADAADGREEDLDQLLEDAYNTQQKEESLELKSKQSSSIAMIQPKSELGKSVQHYLLKKQQQEQQLRHNNHSAAVTSTQQQSIQINSTKQNSIQRSHYTFSLDSTIQKRHDAWDVPQLQMIGGGGSSGQQEQSLFEKRGMTPLDCHLIATIRKKLDGAMNKGGVGGKRKEMNDGGVERIGNIDNVKQLHQQEVHGKEQIHQEDNVITEKTLISNLTNSKKDDSDDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUS1</accession>
    <name>A0AAD8XUS1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_015635</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000045">
        <property type="protein sequence ID" value="KAK1733780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUS1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF147">
        <property type="entry name" value="SEL1L ADAPTOR SUBUNIT OF ERAD E3 UBIQUITIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="14"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="79"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1733780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="304" mass="34411" checksum="3D4DB4880E9C80E2" modified="2024-05-29" version="1">MSSDLEAETGNICCASCDIAEVDVIKLKECNDCDLVRYCSDECQEKHRPHHESKCKERAAELRDEILFRQPESSHHGDCPICFLPLSIDTDESSLYGCCSKLICNGCAYANQKRAFKENLEHNCPFCRKILTKTQEEMIQNNMKRADANDPVALQDMAKRYYHEGDYERSFQYWTNAAELGDAEAHHCLSIMYAKGEGAEKNEKMELYHEEEAAIRGHPTARHFLACMELINERFGRAVKHLIIAANLGFDESVQALKTRYADGKVSKEDFAAALRAHHAAVDATKSPQREVAAKAEATGWRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVA4</accession>
    <name>A0AAD8XVA4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014864</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVA4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="257" mass="28827" checksum="94388E2E5C18733F" modified="2024-05-29" version="1">MEEQQLDPLINAAVLAGDVHQMHMQQQPQNNDLPELPQPATAPPLHRHHHHAQQAAPPPQMVVHNVVHTTMYPPPALGGQPLQSHPTLPQLQQQQQQQIATTAAPPRKKSDHTNYNHQSQSSGNTITLNHPQNETYKLKTNQYLLETSSRLDDAVSELYHYTSLLSNHNKQSSSVECITNMEQSIIPLLKICSNAMKDAGKYFAPFSGTVNIHNRNDAEKKRRLVLEEENKAVLLQQNEEGSGGGNKRRARRSVLRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVE0</accession>
    <name>A0AAD8XVE0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Multidrug resistance-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_015128</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVE0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042626">
        <property type="term" value="F:ATPase-coupled transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF456">
        <property type="entry name" value="MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN LETHAL(2)03659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="28"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1734125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="321" mass="35447" checksum="329700D96A949CFC" modified="2024-05-29" version="1">MGAFVTLSASFCITMFNIGLTAGLSGLLLVWSSCKMDLFDFNLIQAHESDINDYHIGLLNTSLWGSGSAITSIERMHSLEILPQEKSMITSEECKVDKSWPKKGELVFDNVSLRYRPGLPLSWTGCRSQSSMGSVSQWWDELHTGSFRRTRTTQWNVHPSTRPAVFSGTIRSNLDPFLVHSDEELIRALELVKFPHKLLNEAVEEGGGNFSAGEKQLLCLARAMLANPRLLVLDEATSSCDRETDSSVQQMLRSEFPDTTLLTIAHRLDTIIDYDAVIVMENGKVAEMGSPRGLLSSSGIFTDMVNATGPESAAQLKLLVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW56</accession>
    <name>A0AAD8XW56_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_014938</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XW56"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052273">
        <property type="entry name" value="PPIase_FKBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46222">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP7/14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46222:SF3">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0697">Rotamase</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="6">
        <location>
            <begin position="222"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1734431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="330" mass="36271" checksum="D836D1C87D99665C" modified="2024-05-29" version="1">MRRYGECTRDLRGFIFCMVWIIFSSCILAWGLSLPSKHLINRRTAINTAIVSPFLLTSSPSNAVSPTTIENPNPRAITTIRLNSPNQKAGLELYNIQIGTPPRDVVAVKAVQVNGQGARDGAERGMILLDYANREDLIARLTSGVYPIEIRLFNLALGGDSIGDLGRSMVTPEDALQLSSSLSKSDTNASVMGGSAQPPSAGFVINTIKQAQDECMVKSRRGDTMQIRYEARVGDRNGPIYDASEYRGTGQPYAYILGNNDVIKGVDLGTFDMCPGEVRELTIPAELGYRSGSKLFKQIPPNSTLFWKIELVELNFIREGMNNRPREASY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWU3</accession>
    <name>A0AAD8XWU3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cysteine-rich secretory protein-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_014115</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWU3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05380">
        <property type="entry name" value="CAP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051860">
        <property type="entry name" value="Plasmodium_CSP_Invasion"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44826">
        <property type="entry name" value="SPORE COAT PROTEIN SP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="3">
        <location>
            <begin position="468"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="519"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="191"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="244"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="293"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="527"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1735049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="657" mass="71575" checksum="E057E1DB645D983F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXC2</accession>
    <name>A0AAD8XXC2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoglycolate phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_013784</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.18" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXC2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008967">
        <property type="term" value="F:phosphoglycolate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43885">
        <property type="entry name" value="HALOACID DEHALOGENASE-LIKE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43885:SF1">
        <property type="entry name" value="SUPERFAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G13290)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1735621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="266" mass="29580" checksum="4DE16F448D94456A" modified="2024-05-29" version="1">MVSNRSNSSSSSPCGQTVSNQLSATAAAPLKGIIFDMDGTLIQLNVVNELIQRIYQVADEDPLGKCLERDDLDVMIAKLSPEGQRKAKKTIVEILQRHVDNMTIQEGGPELVAFLARNGVKRAVLTRNYERNAIVMQQMYAQVMTEATFDLIIGKDTPYDTSFPPEQEIPKADRIRQICNIWGCDTNEVIMMGDSITDDIVEGNRAGCGGTVLLQPIGYQLNNFYGTRIGDSRERTPTMCVESLTDVRHFFAAQMNNDVCYQQGEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXC9</accession>
    <name>A0AAD8XXC9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXC9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="73" mass="7856" checksum="AF33EFE2067D06C0" modified="2024-05-29" version="1">MNDGIDNLQSGYRNVTSSINENKSSNALKNTDAIIPMLVLHLAAHIGGGTNDNANDAHKELEVTFASNTSRWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXH1</accession>
    <name>A0AAD8XXH1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sig3-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_013891</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXH1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050839">
        <property type="term" value="F:cell adhesion molecule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007157">
        <property type="term" value="P:heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051216">
        <property type="entry name" value="Teneurin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11219">
        <property type="entry name" value="TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11219:SF69">
        <property type="entry name" value="TENEURIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23106">
        <property type="entry name" value="EGF_Teneurin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00011">
        <property type="entry name" value="EGFLAMININ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1 4" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042091097" evidence="5">
        <location>
            <begin position="16"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="6">
        <location>
            <begin position="173"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="198"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1735277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="227" mass="24119" checksum="38EE23FBE001649B" modified="2024-05-29" version="1">MKILLLATILATVGAYCPNACSGHGSCGINASLNLSDKCTCYNRPNGDPAWTGHDCSLRTCPQGSAWASELAVSENNVHPRMECSNKGLCDRESGECSCFENYDGKACERTMCPNDCSGRGICLTQKALAILQGTVYDAPWDADKAMGCKCDDGFRGADCSQKECPSGPDVLNGDGGSEGRDCSGRGICSYETGLCTCFKGYYGTRCEFQTILEASHGRSSQTSGPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYT8</accession>
    <name>A0AAD8XYT8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein CASP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_013359</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CASP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYT8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012955">
        <property type="entry name" value="CASP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057476">
        <property type="entry name" value="Cux_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14043">
        <property type="entry name" value="CCAAT DISPLACEMENT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14043:SF2">
        <property type="entry name" value="HOMEOBOX PROTEIN CUT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08172">
        <property type="entry name" value="CASP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25398">
        <property type="entry name" value="CUX1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cux N-terminal" evidence="13">
        <location>
            <begin position="5"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="CASP C-terminal" evidence="12">
        <location>
            <begin position="515"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="346"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="544"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="75"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="372"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="615"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="358"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="547"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF25398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1736223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="811" mass="90862" checksum="0533B332B9B861D1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYU1</accession>
    <name>A0AAD8XYU1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Serine/threonine-protein kinase</fullName>
            <ecNumber evidence="9">2.7.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_012847</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052420">
        <property type="entry name" value="Espin/Espin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153">
        <property type="entry name" value="ESPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153:SF8">
        <property type="entry name" value="FORKED, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="860"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="917"/>
            <end position="1250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1624"/>
            <end position="1644"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1586"/>
            <end position="1619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1635"/>
            <end position="1644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1736247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1717" mass="190804" checksum="AF5A4D98A0E442A3" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y077</accession>
    <name>A0AAD8Y077_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012018</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y077"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="294" mass="32947" checksum="FEC4ECBAE9417915" modified="2024-05-29" version="1" fragment="single">MRFCTSVNLCTDADYCLASAPLEARNYVLACYAVSLIQGNTILGGSVKHATLNGYIKAVVDMHTDRQLTSPRLVEKDLVSPLLDAVKRYESVPNRRDMIYDSMVSHMLQVTAGLQDDCLHSAILDWIILGRYGGFRQSEWCQTSQSIAMTRPSLALTVQEPLAFIPSDFAFFDSEGRPLPDVEDDSVDMVELTWRFQKNSNNGERIPFKRDYSSPDLCPVLAAVRIRRRAARLGIHSASTLAVYSDPKSVTGYSYITANQTAAFLRTTAQKVFMLDSKDDRLQRWSCHSLRVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0F8</accession>
    <name>A0AAD8Y0F8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA (guanine(26)-N(2))-dimethyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.216</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_012323</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>guanosine(26) in tRNA + 2 S-adenosyl-L-methionine = N(2)-dimethylguanosine(26) in tRNA + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:43140"/>
            <dbReference type="Rhea" id="RHEA-COMP:10359"/>
            <dbReference type="Rhea" id="RHEA-COMP:10360"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74513"/>
            <dbReference type="EC" id="2.1.1.216"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.216" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0F8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160104">
        <property type="term" value="F:tRNA (guanine(26)-N2)-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002940">
        <property type="term" value="P:tRNA N2-guanine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.56.70:FF:000001">
        <property type="entry name" value="tRNA (guanine(26)-N(2))-dimethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.70">
        <property type="entry name" value="N2,N2-dimethylguanosine tRNA methyltransferase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002905">
        <property type="entry name" value="Trm1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042296">
        <property type="entry name" value="tRNA_met_Trm1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10631">
        <property type="entry name" value="N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10631:SF3">
        <property type="entry name" value="TRNA (GUANINE(26)-N(2))-DIMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02005">
        <property type="entry name" value="TRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51626">
        <property type="entry name" value="SAM_MT_TRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 9 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="1 9" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="640"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="707"/>
            <end position="742"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00051897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1736878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="742" mass="81203" checksum="7CA13C88532A3CAC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y177</accession>
    <name>A0AAD8Y177_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011874</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y177"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="567"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="607"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="567"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="668" mass="74444" checksum="8C577B63176A1199" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1R0</accession>
    <name>A0AAD8Y1R0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011884</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1R0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="134" mass="14634" checksum="83DEA7D5A30989D2" modified="2024-05-29" version="1">MSDEDDGSDCGPSLPAGVLRSRGGWAGDSLEIDHQREALQQSESGNNKADHAAVDLSQFRNEEVGKGYQAKHVIRQAGAPSKVSGIVNMSKKDISSKKDESKPKPNDTTTKETYLACRGMRNFIREVDKILEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y275</accession>
    <name>A0AAD8Y275_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y275"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="284" mass="31486" checksum="3CB5535F20AAA1FE" modified="2024-05-29" version="1">MDSETASSFQTTSMERKEALDTRDLRMPVLGREQSRTFSMRTESKSSPVQSRTSSDVTVVERSDSISTKFSGNRNPTIHMPPLNRFQSNSTAGAVVCEADDFMSTMKEFDDEVQQQKMSSNLSGSTMSQTRCTSPNSMSSKIEFSSKTSSSALLNAAMADLDGPPLKQDCGDLLAEGIEHLSMAMLVNIYGKLREMSLLGHVSVKLRDIDVNSHQYNSRKKEMKRLGEWTAADEAKGYLDTTRNAGFIVRAVMDEHELFEAEHARGANSEINHALLAYDARLTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2A1</accession>
    <name>A0AAD8Y2A1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2A1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="509"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="535"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="684"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="137"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="570"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="610"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="684"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="718"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="912" mass="100789" checksum="B0030C471E602FD8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2M3</accession>
    <name>A0AAD8Y2M3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_011169</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2M3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF121">
        <property type="entry name" value="OS09G0315000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1737875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="239" mass="26971" checksum="18359191563A3C1C" modified="2024-05-29" version="1">MMILSVQQHHAVIYHRHDRAAADAGGMQTQYNLQPSVLPNFYKTSPFTAGFITASTRAAIADSIAQRLDVCNDEFDMKRCCAMVLYSGVILGLCCELMFNHIFPVIFAGETNPLVLAVKMALFDVFINAPLIWLPPAYIVQALAYRFPKREAIQRYITDVKQNGLLKKYWSLWLPASLTNFLFVPAHFRVAFVAAVGFFWMIVLSAVANKNNGELEVEICPIDCPQEPEPKMDYPRAME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y398</accession>
    <name>A0AAD8Y398_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_011280</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 5"/>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y398"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000006">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005818">
        <property type="entry name" value="Histone_H1/H5_H15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43811:SF19">
        <property type="entry name" value="39 KDA FK506-BINDING NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43811">
        <property type="entry name" value="FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00538">
        <property type="entry name" value="Linker_histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00526">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51504">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="H15" evidence="7">
        <location>
            <begin position="3"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="6">
        <location>
            <begin position="100"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1737986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="184" mass="19626" checksum="4E8F8B151DC43E44" modified="2024-05-29" version="1">MTPPKTLLDKIVYAIRQQPAASANGVSRAAIVKYLSAEFGVDKTKAASKKAFKDGVSKGILIQTGQSFRVKGDKVPEVSEEPKVVIEELKEGKGPPAQSGDTVTVKYEGKLTDGTIFDSAKSFEFTLGAGEVIKGWDQGIAGMKVGGKRKLFVPSKLGYGKRGAAPEIPPNADLQFEVKLKSIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3G1</accession>
    <name>A0AAD8Y3G1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rhodanese-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3G1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020936">
        <property type="entry name" value="TrhO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040503">
        <property type="entry name" value="TRHO_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43268:SF7">
        <property type="entry name" value="RHODANESE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43268">
        <property type="entry name" value="THIOSULFATE SULFURTRANSFERASE/RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17773">
        <property type="entry name" value="UPF0176_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="225"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="466" mass="52391" checksum="1F3BE101DB660010" modified="2024-05-29" version="1">MSTTEEIPTKHMIALYYCYPPAGLPKDQLEPHKLFHQETCTNLNLGGRIRVSEEGINGVLSGTENALREYEASLRKELLQLVVAVIDNDHDDDPTTEWLDIKYCHLRNDIPTEQQLFDSLQVKITREVVSLIEPTPQNQGKNKGKRCRQRRKQKRKEKQMQEKLAEASVGEDGPSNNVTAKLAAAKEVVNIEDWKNNTPAQHLSPEEWNNKLLELAQQEEEGSFEESEAVLLDTRNIYETRVGHFAVPQLPTLFPNTRKFSSLPLALNTEEAAEALAGKQVFMYCTGGVRCERAGTYLRALSDSNSGAWQGKEKPKAIFQLKGGIQKYLETYGEQVEPKSDDDADAKPCLYRGKNFVFDQRRTDPVIGNGITSKTASDRPERVSSVGQCIICSKIHDDYDNGFSPCDEKEARCCRCRVLVLVCNDCRPNVRSCGEPETDNVTDLLCGRTTCIDEGNIAENVETVRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3Z7</accession>
    <name>A0AAD8Y3Z7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Histone-lysine N-methyltransferase</fullName>
            <ecNumber evidence="13">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_009809</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="13"/>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15545">
        <property type="entry name" value="PHD_BAZ2A_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.890.10">
        <property type="entry name" value="Methyl-cpg-binding Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053114">
        <property type="entry name" value="ATXR5/ATXR6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001739">
        <property type="entry name" value="Methyl_CpG_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48442">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48442:SF1">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01429">
        <property type="entry name" value="MBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50982">
        <property type="entry name" value="MBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Myb-like" evidence="8">
        <location>
            <begin position="19"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="12">
        <location>
            <begin position="19"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="12">
        <location>
            <begin position="72"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="8">
        <location>
            <begin position="72"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="MBD" evidence="11">
        <location>
            <begin position="399"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="9">
        <location>
            <begin position="1132"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="7">
        <location>
            <begin position="1506"/>
            <end position="1556"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="10">
        <location>
            <begin position="1720"/>
            <end position="1842"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="159"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="494"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="542"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="578"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="761"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
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            <begin position="868"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="958"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="241"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="252"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="382"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
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        </location>
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        <location>
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        </location>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1739266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1865" mass="208573" checksum="5D1CFA427DCB629C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y472</accession>
    <name>A0AAD8Y472_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_010784</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y472"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1738754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="67" mass="7832" checksum="DA0169E0C29331DC" modified="2024-05-29" version="1">MADNPQNRSSASANDEGEIRFNQLLDEQDHNRCKEGNKNALLAEKLERLRALRDELAKDNWMFESKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4B6</accession>
    <name>A0AAD8Y4B6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009917</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4B6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1739374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="166" mass="18587" checksum="3C4009AD8E6001FE" modified="2024-05-29" version="1">MSPPQRNNNKAIDTASEEWPEIQTLVSRLAPVDPTPKEVNVNNSLSAQDLKSLKKRDPFLYYSIPGVRDATVRLEHDVDMHQIAQKGLKRQCQSCPASMQTSSTSEPVAKVKRCTRVSFECHTDLLLDLDDLSGSDGLGDMGKALEKYSLEDDSCEEFLFKLLERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4J5</accession>
    <name>A0AAD8Y4J5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_010560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4J5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1738530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="316" mass="35977" checksum="5F6624E5C58846E8" modified="2024-05-29" version="1">MADHADDGDGVGDIFIYRGGRAHLHVTRVVIDKSVEEIENNAFDGCEQMVHVETHDGIRKVGGINLKSAIEIDRAAFYCCRNLESVEFGENLEIIGGTAFHGCSSLERLNLPSIIVIEEAAFYNCKALTDIELSERLETIESAAFRACERLQRIAIPLKRNLFSFFVRHDHNQIYNQFDKCDQLTTVDLVGGIHTTVASLHMESWKTEMKETISRINQVLPDADQGDKIAIIRQWMDSVIDKMVHYKAEHYRYVKEAITLLELALWKAKLGAREDNYAEGRTRKTKTDVECARRERRVICGADTVIKNVLPFLYLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4P7</accession>
    <name>A0AAD8Y4P7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_010796</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 17">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4P7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF803">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="14">
        <location>
            <begin position="273"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="62"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="147"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1738766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="685" mass="75251" checksum="DD19AD05521EEAD7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4S1</accession>
    <name>A0AAD8Y4S1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RecQ-mediated genome instability protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_009460</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RMI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4S1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016604">
        <property type="term" value="C:nuclear body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031422">
        <property type="term" value="C:RecQ family helicase-topoisomerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.770">
        <property type="entry name" value="RecQ-mediated genome instability protein Rmi1, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042470">
        <property type="entry name" value="RMI1_N_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013894">
        <property type="entry name" value="RMI1_OB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14790:SF15">
        <property type="entry name" value="RECQ-MEDIATED GENOME INSTABILITY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14790">
        <property type="entry name" value="RECQ-MEDIATED GENOME INSTABILITY PROTEIN 1 RMI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08585">
        <property type="entry name" value="RMI1_N_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecQ mediated genome instability protein 1 OB-fold" evidence="4">
        <location>
            <begin position="211"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="147"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="298"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="98"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="298"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="315"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="351"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="396"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="407"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="425"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="447"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="460"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="472"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1739701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="722" mass="79101" checksum="A44673338479CABC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5C3</accession>
    <name>A0AAD8Y5C3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_008939</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1739989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5C3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF147">
        <property type="entry name" value="SEL1L ADAPTOR SUBUNIT OF ERAD E3 UBIQUITIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="285"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1739989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="510" mass="56600" checksum="BAD6C188A633B4F9" modified="2024-05-29" version="1">MKFYSSSPKAAISYDRNMSIMTACCSKWICRGCGHANQMREAEEKMAKKCPFCRSPVPTSKEGVDKDAMKRVEVNDPAALRHMGIARYNEGNYKSSFAYLLKGAELGDVGAHYQISLLYRDGEGVEKDVKKKVYHLEEAAIGGHLGARYNLGNHECRNSRHDRAAKHYIIAANLGHEGSLQALKKGFKAGWVSKEDFAAALRAYQAAIDAMKSPQRDEAEAFVALQSTLDVAPSSLCVVSGKDFSVGDISVGVVFRSGGAVTLLSSSSSTMMSGVVEESDDMMCCAACGTAGIDEIKLKDCSACKLVKYCSVKCQKEHRPQHKRACKKRAAELRDEILFKQHESTHLGDCPICCLPLQYDNDKSTMMSCCCKTICNGCEYANRMREFEGKLKHTCPFCRHPLPNFEEEIRKNYMKRIEEEADKNYMKRIEANDPVAFFEMGLRRRDEGDIEGAFKYMTKAAELGDAGAHYVLSGMYAEGKVVEKDEKKEMHHLEEAAIAGNPMLGTISDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6X5</accession>
    <name>A0AAD8Y6X5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Conserved oligomeric Golgi complex subunit 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008737</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6X5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048682">
        <property type="entry name" value="COG4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24016">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24016:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="514"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="550"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="524"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="873" mass="95769" checksum="BE5CB1E714D67932" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6X8</accession>
    <name>A0AAD8Y6X8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Aminopeptidase N</fullName>
            <ecNumber evidence="14">3.4.11.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_009263</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.2" evidence="14"/>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6X8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016285">
        <property type="term" value="F:alanyl aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09600">
        <property type="entry name" value="M1_APN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.390.10:FF:000002">
        <property type="entry name" value="Aminopeptidase N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2010.30:FF:000002">
        <property type="entry name" value="Putative aminopeptidase N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.10">
        <property type="entry name" value="Peptidase M1, alanyl aminopeptidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038438">
        <property type="entry name" value="PepN_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012779">
        <property type="entry name" value="Peptidase_M1_pepN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024601">
        <property type="entry name" value="Peptidase_M1_pepN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037144">
        <property type="entry name" value="Peptidase_M1_pepN_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035414">
        <property type="entry name" value="Peptidase_M1_pepN_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02414">
        <property type="entry name" value="pepN_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46322">
        <property type="entry name" value="PUROMYCIN-SENSITIVE AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46322:SF1">
        <property type="entry name" value="PUROMYCIN-SENSITIVE AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11940">
        <property type="entry name" value="DUF3458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17432">
        <property type="entry name" value="DUF3458_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 14" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041988520" evidence="9">
        <location>
            <begin position="20"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="13">
        <location>
            <begin position="177"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="10">
        <location>
            <begin position="339"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 alanyl aminopeptidase Ig-like fold" evidence="11">
        <location>
            <begin position="558"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 alanyl aminopeptidase C-terminal" evidence="12">
        <location>
            <begin position="654"/>
            <end position="991"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF11940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1740313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="992" mass="109716" checksum="DDA8D81850CAD66D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7F9</accession>
    <name>A0AAD8Y7F9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ankyrin repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008215</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7F9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24186:SF38">
        <property type="entry name" value="ANKYRIN REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24186">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="371" mass="42152" checksum="AB827C08C33E8A11" modified="2024-05-29" version="1">MSNAATSLRSQLDYLIHRFRDDTIIDGEATALINEVRLALEEDFVVLISQYSQEDLQAAVLLTYDDSRRLPLHLACDKNAPMSILKALLDADVDKLSIREADRWGDLPLHTACSRKQTEVVELLVDSDSSKQTLYIKADNGSLPIHTAARYSAPASVITLLLDSAESRKTLLEPDVFGQLPLHAACRNGASPDVIGLLLDFDNEKETVMIEDNVGRLPVHLALLHTTKDQIEVVRIILQHMICTRMERKGLDLWKTEIKNMLTSMQTHERDFTTRDKLDMISDAMRNFNARVFTLELTVWRASCLQFDTRFQSMEDVLEHESSQASGDFDSHAYKLDRRIKSGADIIVRDVMSFVENEPVDEVIDQFKNYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7U4</accession>
    <name>A0AAD8Y7U4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008858</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7U4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031415">
        <property type="term" value="C:NatA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051556">
        <property type="entry name" value="N-term/lysine_N-AcTrnsfr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42919:SF20">
        <property type="entry name" value="GCN5-RELATED N-ACETYLTRANSFERASE 10, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42919">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041940990" description="N-acetyltransferase domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="161"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="309" mass="33263" checksum="E755FFA9DF0DE016" modified="2024-05-29" version="1">MKSSLLLAASALFGSQTAFVSSFSTNGAALQSKTPMKLDMFFATEAADDDTAAASTTKESMDVKLTPLDGSESSVINAAKFMVDSFWLQSPQNLIDGGGDLSSISDASKSSLTNIQADDLLSKYGERMGKRKLDALIVVASDGSSDTKSLSADDILGLVTIEVRLLNSNDLLSADESEFRLTQAVASLGPKQRREYKDASVLDIARELLPPEVTAVCSLSNLCTSPKARRMGIAAKLCSEAERLTKEELSFDEIYLRVESENEAAKKLYEDKLGYQCKFEASATALRVDAERGGFVEVDSDIVVMSKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y902</accession>
    <name>A0AAD8Y902_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">UDP-glucuronate 4-epimerase</fullName>
            <ecNumber evidence="6">5.1.3.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_007451</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.6" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y902"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050378">
        <property type="term" value="F:UDP-glucuronate 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43103:SF3">
        <property type="entry name" value="ADP-L-GLYCERO-D-MANNO-HEPTOSE-6-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43103">
        <property type="entry name" value="NUCLEOSIDE-DIPHOSPHATE-SUGAR EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041982745" evidence="4">
        <location>
            <begin position="39"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="5">
        <location>
            <begin position="280"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="45"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1741878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1002" mass="111167" checksum="C43085156131F7DB" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9E5</accession>
    <name>A0AAD8Y9E5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_006816</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9E5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1742251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="265" mass="29720" checksum="D30377E986CBCD62" modified="2024-05-29" version="1">MVNTCPEALNERLGRRTLLHYVISEGMDIQIIKYITTQAPTLISQTDSFGSIPLHLAASYPSSSRPVLSHLLEIYPDGAHALDHRSQTALHRACKSRASLSKVLALIEANPKALFWRDHGKNTPLNWAEKFDHSLTDVCPEVVELISMMEDILTLQCSERVSNGQYAHDHTTDVLHDDTIIDEERQRAKEILSHFQAMSWYEGIRIAFACNRNLISLIEVQLELYPTLLSILAHPNCGCVGKNFGLESTYAILLRCPGAFGVDRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YB47</accession>
    <name>A0AAD8YB47_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Thioredoxin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_007403</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YB47"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43601">
        <property type="entry name" value="THIOREDOXIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43601:SF32">
        <property type="entry name" value="THIOREDOXIN-LIKE 2-2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="76"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="65"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1741830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="218" mass="24726" checksum="47D3EC9CBDC7B802" modified="2024-05-29" version="1">MAGLVSASLNQRSILVGILVIVCNNVFTAAAWTTTAPTSIQRSHKNYPHSSHRIRLSTTQLSYRDDEHDTLESKKKSSPPPAKDFQSRMKRMAMRRRETGKSWRPPNVQTATSLEDFANVIQEGRTKNQLVVVRFYANWCKKCQALRPSFDKVASSKPQVIFVDVPVTNTNVELHQGLGVKSVPFAHIYCPEKGLVVEEKISRRRFSEFEELVEQHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YB82</accession>
    <name>A0AAD8YB82_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">UDP-glucose 6-dehydrogenase</fullName>
            <ecNumber evidence="3 8">1.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_006706</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>UDP-alpha-D-glucose + 2 NAD(+) + H2O = UDP-alpha-D-glucuronate + 2 NADH + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:23596"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="1.1.1.22"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; UDP-alpha-D-glucuronate biosynthesis; UDP-alpha-D-glucuronate from UDP-alpha-D-glucose: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.22" evidence="3 8"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YB82"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003979">
        <property type="term" value="F:UDP-glucose 6-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006024">
        <property type="term" value="P:glycosaminoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.100:FF:000001">
        <property type="entry name" value="UDP-glucose 6-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000032">
        <property type="entry name" value="UDP-glucose 6-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000114">
        <property type="entry name" value="UDP-glucose 6-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.100">
        <property type="entry name" value="Cytochrome c1, transmembrane anchor, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028356">
        <property type="entry name" value="UDPglc_DH_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11374:SF3">
        <property type="entry name" value="UDP-GLUCOSE 6-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11374">
        <property type="entry name" value="UDP-GLUCOSE DEHYDROGENASE/UDP-MANNAC DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500133">
        <property type="entry name" value="UDPglc_DH_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="UDP-glucose/GDP-mannose dehydrogenase C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 10" id="KW-0520">NAD</keyword>
    <keyword evidence="5 8 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDP-glucose/GDP-mannose dehydrogenase C-terminal" evidence="11">
        <location>
            <begin position="332"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="276"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="12"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="90"/>
            <end position="94"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="131"/>
            <end position="132"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="276"/>
            <end position="279"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="346"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR500133-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR500133-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1742141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="474" mass="52488" checksum="46AA85C8AD7BC97F" modified="2024-05-29" version="1">MSEFTLNICCMGAGYVGGPTMAVIALKCPQIRVCVVDLSQKQIDAWNSDSLPIYEPGLPEVVSECRGRNLFFSTDIDGEIKRADIIFISVNTPTKTMGIGAGRAANIKNCELCARKIAEVSDSGKIVVEKSTVPVRTAQAVRRVLECNDKGLKFQVLSNPEFLAEGTAMEDLKAPDRVLIGGVQDEDGIKAAETLVSVYANWVPREQILTTNLWSSELSKLVANAFLAQRVSSINSISALCEATGADVNEISRAVGIDQRIGRRFLNSSIGFGGSCFQKDILNLVYLCETYGLHECAEYWNQVIVMNDYQKKRFTEKMVSSMFNTVTGKKIAILGYAFKKDTGDVRETPSMFVVRDLVLEQAKIHVFDPQVKREDMWIEMDYTCGMTEKTHPGLDKAVTTSPDAYSACDGAHAFAVLTEWDEFKTLDFERIYKGMAKPAFVFDGRNILDHAKLREIGFEVHAIGKPDPNKFSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBB3</accession>
    <name>A0AAD8YBB3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PAP2 family protein</fullName>
            <ecNumber evidence="4">3.1.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006892</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBB3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042392">
        <property type="term" value="F:sphingosine-1-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14969:SF13">
        <property type="entry name" value="AT30094P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14969">
        <property type="entry name" value="SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042068599" evidence="2">
        <location>
            <begin position="30"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="3">
        <location>
            <begin position="119"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1742327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="316" mass="33758" checksum="5553D8032E087980" modified="2024-05-29" version="1">MPSPRSSHCLLSAALIIISSAIDATLVDAFTVPATVRAIPSEANAIINHYRHERKNLNLPHKQEMIVTLNSSSNNSEEVRTDSLPSNSLFDGATTVIGKSASSLVSLSFFLLLSTQRDAITTTLFIGSILNAISGKILKKLINHERPAELELSDKVKLKPSDGGMPSSHAMSLSFIGTVILLGVIVPATTTAAGGGSSSIMSITGGALMVIYSAIALRYRVRDHLHTLDQIIVGYGLGLFNAIVWLKFAVNNNDGAVRPVVSMVQKYLISSETNQFPVVGLLVPILVGVLVVGSFERRIGVWLKERNGGGGEDKMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBE3</accession>
    <name>A0AAD8YBE3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Nitroreductase family protein</fullName>
            <ecNumber evidence="10">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_006639</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nitroreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="10"/>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1743042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBE3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02135">
        <property type="entry name" value="YdjA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="entry name" value="NADH Oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052530">
        <property type="entry name" value="NAD(P)H_nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026021">
        <property type="entry name" value="YdjA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43821">
        <property type="entry name" value="NAD(P)H NITROREDUCTASE YDJA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43821:SF1">
        <property type="entry name" value="NAD(P)H NITROREDUCTASE YDJA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="FMN-dependent nitroreductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042003199" evidence="8">
        <location>
            <begin position="20"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Nitroreductase" evidence="9">
        <location>
            <begin position="51"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1743042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="235" mass="26018" checksum="901B272AD029FF48" modified="2024-05-29" version="1">MRSIICILVAAAQLLATDAFTTPQTTITTTTRSSQLNARPEARSREVHKNILSRRTINEFEPTLPDNWEKALEKSIEAAIYAPNHKRTEPWRFYLLGPKSIEKVCQLNADIVASKKGEEAGQKKLKRWLQMPGWLVVTCVKGDDDFNNPTSLAREDYAACCCAVQNLCLSLHSQGIGTKWTTGPVNFDDRFAEAVGFAPEKEFTVGTLWFGSAVGSTPSPPLKKLAVEGTFTKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YC95</accession>
    <name>A0AAD8YC95_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Ion transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">QTG54_005784</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R05AC</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. Two pore calcium channel subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YC95"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034702">
        <property type="term" value="C:monoatomic ion channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005245">
        <property type="term" value="F:voltage-gated calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044581">
        <property type="entry name" value="TPC1_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46988">
        <property type="entry name" value="TWO PORE CALCIUM CHANNEL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46988:SF2">
        <property type="entry name" value="TWO PORE CALCIUM CHANNEL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="8" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="252"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="317"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="545"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="583"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="612"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="699"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="15">
        <location>
            <begin position="357"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1743163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="801" mass="91866" checksum="A13D56F061E4B1F9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YC96</accession>
    <name>A0AAD8YC96_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vam6/VPS39/TRAP1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YC96"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034058">
        <property type="term" value="P:endosomal vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1480">
        <property type="entry name" value="Coatomer, gamma subunit, appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013041">
        <property type="entry name" value="Clathrin_app_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013040">
        <property type="entry name" value="Coatomer_gsu_app_Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037067">
        <property type="entry name" value="Coatomer_gsu_app_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032914">
        <property type="entry name" value="Vam6/VPS39/TRAP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894">
        <property type="entry name" value="CNH DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894:SF27">
        <property type="entry name" value="TRANSFORMING GROWTH FACTOR-BETA RECEPTOR-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08752">
        <property type="entry name" value="COP-gamma_platf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49348">
        <property type="entry name" value="Clathrin adaptor appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Coatomer gamma subunit appendage Ig-like subdomain" evidence="1">
        <location>
            <begin position="502"/>
            <end position="640"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="678" mass="74593" checksum="48BC9B4E476BB7B8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCE5</accession>
    <name>A0AAD8YCE5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MOSC domain-containing protein</fullName>
            <ecNumber evidence="3">1.7.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006572</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.7.-.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCE5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005303">
        <property type="entry name" value="MOCOS_middle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237:SF19">
        <property type="entry name" value="MITOCHONDRIAL AMIDOXIME REDUCING COMPONENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SULFURASE MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03473">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03476">
        <property type="entry name" value="MOSC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141673">
        <property type="entry name" value="MOSC N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="MOSC" evidence="2">
        <location>
            <begin position="215"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="399" mass="44402" checksum="C27019E983E454FD" modified="2024-05-29" version="1">MMIADNNFSTVAVCTAIVIVLLNIFHPKRIHLLIKSHRARMELRKLCAQKQIDEDSSTTQDDDDRPRVSGIFIHPIKSMRPVSITETKFDKHGLLSDRRLMLVRPLPTPLHGSFAKGEATHRFFTQRQAPSLATIELTPVLSQDRTRILLKLSSKLSGSNDHAYIDTHPHTIKKYPVRYSAGVWSDVVEVADVGDDAAEYVASIVCKDDPSFKDVRVVSILESSMRKVSDKYCPDAARVGFFSDLPQGGLTDGFPILVATEASLELLNQKLKEKGKDSIPMSRFRPNIVIGKTNKAFDEDNWKAIKIGRGKDAVILHLVKGCPRCKQSCTNQLTGERGEEPVATLSEFRALGRSAEDVYFAQNAVLNGDSYNKGIQVGDPVTILTRGEDVWDMEDVQAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDP1</accession>
    <name>A0AAD8YDP1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pescadillo homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_006211</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
            <location evidence="4">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
            <location evidence="4">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the pescadillo family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDP1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070545">
        <property type="term" value="C:PeBoW complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000466">
        <property type="term" value="P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd17709">
        <property type="entry name" value="BRCT_pescadillo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03028">
        <property type="entry name" value="Pescadillo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010613">
        <property type="entry name" value="PES"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12221">
        <property type="entry name" value="PESCADILLO - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12221:SF6">
        <property type="entry name" value="PESCADILLO HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16589">
        <property type="entry name" value="BRCT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06732">
        <property type="entry name" value="Pescadillo_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2 4" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="BRCT" evidence="6">
        <location>
            <begin position="437"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="334"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="585"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="656"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="341"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="355"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="380"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="589"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="666"/>
            <end position="712"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1743590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="724" mass="81201" checksum="A0795B5B9BB63676" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEN7</accession>
    <name>A0AAD8YEN7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cyclin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_004986</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEN7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000093">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0195">Cyclin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="3">
        <location>
            <begin position="80"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="311"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1744453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="343" mass="39698" checksum="4A41FFB5F55DC67F" modified="2024-05-29" version="1">MTIPPQTTLTTECVVVEDLCERLKGMRRKEISTHYRIPDYLAPEWQALLVEEAARDDSELPNPDEEITQINEQWRVKICDWCYQVVDHFDYNREVVTVAMSYLDRYIAKRTVNRRIFQLVAMTALYLATKLFERNSLHLPSLVGISRGYFLAEHIVAMEDSMLQALSWHVHPSTPRAFCWEMMRLVSPELTPRIRHDIGNLAIFLTELSVCDYYFVTRKFFSCTSNDHLSCHLFYHCLTLTFNETGKNSSIAIASIMNAIELMGPKKIEPKYKVHFLHNIVRIGLDIADDDEIIECYERLREMYIEGGYTPTSEDDVDVDVQPPDTANTNKRKRDGGDTIVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YER7</accession>
    <name>A0AAD8YER7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005712</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YER7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="161" mass="18290" checksum="3DCB7919666A47F6" modified="2024-05-29" version="1" fragment="single">TDDNNSDDPSWNEVHFQKTLKTLVEKGDLLQINGINYKFSNQYLQRRVEALRARAESIEEQTHKTAVEHHHAREIPSKEAPKKKTVHAKMKINEGKIITVVNPEVKHEDDMDTTPTDEIDVEGVGMRAAVGKNKKHVKIIPRKVVGTTKNIRMKESSMSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFI9</accession>
    <name>A0AAD8YFI9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005632</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFI9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="632" mass="71012" checksum="D1DC8704EB7C473D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFP3</accession>
    <name>A0AAD8YFP3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fatty acid hydroxylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004314</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFP3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="262" mass="29506" checksum="F6B32D1382C70DD4" modified="2024-05-29" version="1">MCNPKTFTAATPTRRPSMRAQQQKLQSVVLDSATALFVFITSTTIHLVAMIEKLFKCKVLPTREPGAPPVRYVSLDLRSVTYLSINSLNEYAFVMRLTHYLWHGGHLQMVPWRMEEISVANTILALGIMLVSMDLLYAPLHHFLHLPSMYPLIHKHHHRQHYPVRGYLDAGNEHPIEHMIGVVCTWFAVLTAEMLLPSCQLWLTGNAHSPDLVTKGGGVHAVTVLIFFNLHAALAMLNHSPYNVNFSMPFIGSSNLFGKDND</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFP7</accession>
    <name>A0AAD8YFP7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFP7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="1">
        <location>
            <begin position="259"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1249" mass="140978" checksum="3A4C2CAD9387A437" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFV0</accession>
    <name>A0AAD8YFV0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Zinc metalloprotease (Family M50)</fullName>
            <ecNumber evidence="15">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_004105</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M50B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="15"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFV0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044838">
        <property type="entry name" value="EGY1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31412">
        <property type="entry name" value="ZINC METALLOPROTEASE EGY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31412:SF0">
        <property type="entry name" value="ZINC METALLOPROTEASE EGY1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="7 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042049037" evidence="14">
        <location>
            <begin position="19"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="567"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="664"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="712"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="114"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1744814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="730" mass="80025" checksum="24DD1DCD95D31E54" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGM3</accession>
    <name>A0AAD8YGM3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sulfotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003502</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGM3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005331">
        <property type="entry name" value="Sulfotransferase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03567">
        <property type="entry name" value="Sulfotransfer_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="467" mass="52675" checksum="097D587E4EEEDF12" modified="2024-05-29" version="1">MTMVVVMKQNQAVLSSSSSGTKKRGQIILRSAVLAICVVATVLFILSLQMTLKLHSEDSTAGVVHKSLREFDGKVVSNDTEETQLVPATIEDDSQSSMYKVIDRSKRTVIPDKDRSLAFVHIGKSGGSTISLLLRNGCIQAAEGETCEEERWKKFPGKVGETETIASQRIQFYLHVSNVDSGKMAEYYSRVSSIVVVARDPLDRWISAFLSRHPDNIDGMRLRNRAASLRAQARGQTPPIWAQKRVFGIDGVRNDQIHRVAYDGCYPNVQEFVDCATTDEPPSENDLYNTRIMFMEKAKMHFEQVTLNCRETCKEIAAATSRYIHHVRVNYEAYLKELPSDKEVFVIRTKSLWQDWVKVNNLLGSPKDVAIPDSINEGKVVNTQDRLPVRSNLSNEGRESLCKLLRNEYILYIDLLNRAVNLSDSDIKSALDDVHKNCPAILESIGRNSYKISKWRSTLQKNENTIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGT8</accession>
    <name>A0AAD8YGT8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_004570</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGT8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216:SF65">
        <property type="entry name" value="PAXILLIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216">
        <property type="entry name" value="PAXILLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042104429" evidence="4">
        <location>
            <begin position="20"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="337"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="601"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="1056"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="230"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="682"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="282"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="322"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="682"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1745279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1137" mass="124374" checksum="A888FED952FC7BD0" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHF8</accession>
    <name>A0AAD8YHF8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004648</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHF8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24186:SF38">
        <property type="entry name" value="ANKYRIN REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24186">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="252" mass="27878" checksum="A6A4E722FD778536" modified="2024-05-29" version="1">MVRYVRWDGMSLLHYAASNHLPRAVEVCRLLIQAFRGLVLELDESTDDLYLQPLHTACHRGNLPVVECILDMHPDAIRGESSDGSFPIHYAVHALTRTPQAAVEVVKNLLSVDPSVASQEVNGITNAYPLINVCVMPNVLSWNAGLEVIKLLYNAYPEAIVNAEEIFRRGIDISHFVDAVRDFINEQLRYATQASNLQLVRTQDGNGRLPLHHALEEVAPWGAIKLLVQADPATLQIPDSEGSLPLHIAASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIA1</accession>
    <name>A0AAD8YIA1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ion transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_003635</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIA1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005216">
        <property type="term" value="F:monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052420">
        <property type="entry name" value="Espin/Espin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153">
        <property type="entry name" value="ESPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153:SF8">
        <property type="entry name" value="FORKED, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="378"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="417"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="456"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="487"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="520"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="632"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="730"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="9">
        <location>
            <begin position="380"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1745711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="849" mass="95714" checksum="B349B8FC3A99EBEE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIU0</accession>
    <name>A0AAD8YIU0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sulfoquinovosyl transferase SQD2</fullName>
            <ecNumber evidence="4">2.4.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_003905</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIU0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03814">
        <property type="entry name" value="GT4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050194">
        <property type="entry name" value="Glycosyltransferase_grp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45947">
        <property type="entry name" value="SULFOQUINOVOSYL TRANSFERASE SQD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45947:SF3">
        <property type="entry name" value="SULFOQUINOVOSYL TRANSFERASE SQD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase subfamily 4-like N-terminal" evidence="3">
        <location>
            <begin position="84"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="2">
        <location>
            <begin position="274"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1745981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="505" mass="55978" checksum="C0DEE76A2F358E9C" modified="2024-05-29" version="1">MKLYSAAVIASLAASTSSAFAPAPSSLSRATVKTSSTTTTSNTINLFATSPTASSSEMTVPPLKRNPPRKIALLIEPTPFTHVSGYANRFKEMLRYLSKAGDDVTILTTDSKTPTDELPQESFGYDIEHTQGFVFPLYNHITLTFDLPEMKGAKMMEKKRPDLIHVTSPGFMLFAGLFYARVMRIPLLLSYHTHLPLYGRNYLGFVPGIEEIAWALMRFCHSRADLTLVTSPQMKEEMEANGIPRVDVWRKGIDTVRFDPKFKSEEMRKKMTDGNEEDFLMVYVGRLGAEKRLKDIKPVLEQIPNARLCIVGTGPQEDELKEHFKDTKTVFTGQLSGDELSSAFASADAFMMPSDSETLGFVVLESMASGVPVVGCAAGGIPDLIRDGDTGFLVQPGDTEGYLNCAKKLMDTKYRSEMGVRARTEAEQWGWEAATSVLRNVQYEKALINFHKRAFGGFGSANTVGVWRLLRMRIARVFQKLRIPGFRKVKADEDDGSIDAQAQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJH1</accession>
    <name>A0AAD8YJH1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dynein heavy chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_001692</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJH1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005858">
        <property type="term" value="C:axonemal dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000153">
        <property type="entry name" value="Dynein axonemal heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.490.20:FF:000006">
        <property type="entry name" value="Dynein axonemal heavy chain 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041228">
        <property type="entry name" value="Dynein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043160">
        <property type="entry name" value="Dynein_C_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004273">
        <property type="entry name" value="Dynein_heavy_D6_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46532:SF11">
        <property type="entry name" value="DYNEIN AXONEMAL HEAVY CHAIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46532">
        <property type="entry name" value="MALE FERTILITY FACTOR KL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18199">
        <property type="entry name" value="Dynein_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03028">
        <property type="entry name" value="Dynein_heavy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein heavy chain region D6 P-loop" evidence="1">
        <location>
            <begin position="52"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain AAA lid" evidence="2">
        <location>
            <begin position="198"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain C-terminal" evidence="3">
        <location>
            <begin position="348"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1747729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="646" mass="72748" checksum="022903FFD3A42D5C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YK86</accession>
    <name>A0AAD8YK86_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Orotidine 5'-phosphate decarboxylase</fullName>
            <ecNumber evidence="7">2.4.2.10</ecNumber>
            <ecNumber evidence="8">4.1.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">OMP decarboxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">QTG54_002393</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>orotidine 5'-phosphate + H(+) = UMP + CO2</text>
            <dbReference type="Rhea" id="RHEA:11596"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="EC" id="4.1.1.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the OMP decarboxylase family. Type 2 subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.10" evidence="7"/>
    <dbReference type="EC" id="4.1.1.23" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YK86"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004588">
        <property type="term" value="F:orotate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004590">
        <property type="term" value="F:orotidine-5'-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04725">
        <property type="entry name" value="OMP_decarboxylase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000008">
        <property type="entry name" value="Orotate phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01208">
        <property type="entry name" value="PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018089">
        <property type="entry name" value="OMPdecase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011995">
        <property type="entry name" value="OMPdecase_type-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001754">
        <property type="entry name" value="OMPdeCOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023031">
        <property type="entry name" value="OPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004467">
        <property type="entry name" value="Or_phspho_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00336">
        <property type="entry name" value="pyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02127">
        <property type="entry name" value="pyrF_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43375">
        <property type="entry name" value="OROTIDINE 5'-PHOSPHATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43375:SF1">
        <property type="entry name" value="OROTIDINE 5'-PHOSPHATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00215">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00934">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00156">
        <property type="entry name" value="OMPDECASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="14 18" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Orotidine 5'-phosphate decarboxylase" evidence="17">
        <location>
            <begin position="17"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00011971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00012321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00021923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00033428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1747049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="526" mass="56030" checksum="6764C40B779ED63C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKD2</accession>
    <name>A0AAD8YKD2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_000145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKD2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1748206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="116" mass="12906" checksum="F8C66CA0A630BE11" modified="2024-05-29" version="1">MQKQILKFIVPDLGATIDIPLSRAEMEGMKDGSMIAKVMTKKIEPAIFDYMARTSHTCVICNSNRANRMTCNLAPYPNSPEGPSVYAFNPYPVCFSSLCNAESTRRAHEIDVNCQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKG8</accession>
    <name>A0AAD8YKG8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Autophagy-related protein 9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_002021</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Preautophagosomal structure membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ATG9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1748058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKG8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005776">
        <property type="term" value="C:autophagosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034497">
        <property type="term" value="P:protein localization to phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007241">
        <property type="entry name" value="Autophagy-rel_prot_9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13038">
        <property type="entry name" value="APG9 AUTOPHAGY 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13038:SF10">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04109">
        <property type="entry name" value="ATG9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0072">Autophagy</keyword>
    <keyword evidence="8 10" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="406"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="491"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="531"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1748058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="937" mass="105739" checksum="B754C3058509BA92" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKY6</accession>
    <name>A0AAD8YKY6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Serine hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002531</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKY6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF6">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="2">
        <location>
            <begin position="65"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="309" mass="33887" checksum="119B4700DD70BF2D" modified="2024-05-29" version="1">MVVSSFSRLFLISCVAQRNIASSPVQAFFASNQVPTIPLHQMHHRRLSSSAVAATTSTRDDGDAFRILCLHGKGGNGEEFLKRLLPLRALLDDRLVDEKNKSDDVFARNKSIKWEALTAPYQISDSDDAYAWWTMSPGVRSFNADEYIGFDKSASNVMNAVFPNNDSSTTATECSYDLIFGHSQGAILLSALLATNIDLQRSNCSYILNGAAWPNPYGKALMSLPVQQSQHEMKKDTKMLFVMGKSDNINPIESAKQVHDCYQAAGIDVSIVYHEGGHSVPNGGDVDSERALEDVCDFILQAVSGKAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKZ2</accession>
    <name>A0AAD8YKZ2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_000463</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKZ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1748524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="62" mass="7070" checksum="BE2ACFA574B2763E" modified="2024-05-29" version="1">MRTVGSMDVERKIKPLKDTILTKDRNLLKDPKGVALYRLRENLNFIMKAKKELGKKVAGSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YL06</accession>
    <name>A0AAD8YL06_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">tRNA pseudouridine(38-40) synthase TruA</fullName>
            <ecNumber evidence="6">5.4.99.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_001258</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.12" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YL06"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160147">
        <property type="term" value="F:tRNA pseudouridine(38-40) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00171">
        <property type="entry name" value="TruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142:SF0">
        <property type="entry name" value="TRNA PSEUDOURIDINE SYNTHASE-LIKE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pseudouridine synthase I TruA alpha/beta" evidence="5">
        <location>
            <begin position="276"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="98"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1747295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="766" mass="86123" checksum="C51F40640CEC762E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YM80</accession>
    <name>A0AAD8YM80_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fatty acid desaturase</fullName>
            <ecNumber evidence="4">1.14.19.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_001763</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YM80"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016717">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042759">
        <property type="term" value="P:long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006636">
        <property type="term" value="P:unsaturated fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03506">
        <property type="entry name" value="Delta6-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353:SF19">
        <property type="entry name" value="DELTA(5) FATTY ACID DESATURASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353">
        <property type="entry name" value="FATTY ACID DESATURASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041938011" evidence="1">
        <location>
            <begin position="21"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="2">
        <location>
            <begin position="86"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid desaturase" evidence="3">
        <location>
            <begin position="203"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1747800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="462" mass="51451" checksum="8825E31761EACAC0" modified="2024-05-29" version="1">MKLHQACLAIALVGSTSVNGFSSPRMTMPSVSRTARFSAVVEEVTTTNGATASMEMPTAWECDEEAECVEVPACNDEECRTTLDVRIHSKWYDLSGWRKAHPAGAHWIDWYDGRDATEVMDAFHSAKGREMYKRLPASAPDTAAVLEASTAPYSQTELNFRKLRAELEEDGWWNRDFVHEGTLLAIWTSLFVGATLTVESAPPLSCFLLGLTMTNAGWLGHDYIHAVAAGLGPTWWSDKHNKHHALTNEMGVDEDIATDPFLFPYAPDPENDSPLLAVNGVEEKRPDAKNELWYLLAHYAVLLTIFPLQVWVPAVFLSGLMSALIVTPTHQSEEFFEEYQPDWVTAQFQSTRNAVTTNPFSEWLWGGMQYQLEHHLFPSMPRSKYPLLRPILQKFADENNVPGGYRESGEFEILYMNWDLYRKVAEADPVPGAPYSRGNGQLGAIDMQGGVAAGGVGLGKLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YND7</accession>
    <name>A0AAD8YND7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sorting and assembly machinery component 50 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_000341</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAM50/omp85 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YND7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.50">
        <property type="entry name" value="membrane protein fhac: a member of the omp85/tpsb transporter family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039910">
        <property type="entry name" value="D15-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815:SF18">
        <property type="entry name" value="SORTING AND ASSEMBLY MACHINERY COMPONENT 50 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815">
        <property type="entry name" value="SORTING AND ASSEMBLY MACHINERY SAMM50 PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="domain" description="Bacterial surface antigen (D15)" evidence="7">
        <location>
            <begin position="393"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1748402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="653" mass="70076" checksum="DB8C34F1109ED734" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YNQ4</accession>
    <name>A0AAD8YNQ4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000594</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YNQ4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="546" mass="63011" checksum="34EC12AA2DAA39E8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPG6</accession>
    <name>A0AAD8YPG6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001058</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPG6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041917999" evidence="1">
        <location>
            <begin position="23"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1749119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="361" mass="40344" checksum="0E9056D1BF95D5F3" modified="2024-05-29" version="1">MMLLASSAIVAYVLLLAPLTIALSVWDGVIGSDQRMALHRYASKAGLEHKSFSRPLDQSNNNGNNIIERTLDAILTEIESKDNNIHGKQQYVEYWTRQEWRHIEAHSDVDEALAKMHDQNPSLLVDDELESKFSATYSNTHGFRFPSNGHVLYLQVGSEVKGPTCVFPSRSSGGDLLQSNEHQEKACATEGGNHQDNGDIKLVTVPAVSGRLLRFDGQDLHAVPRPHDLWMLPFVKGGAEYKPEEVWGRSVILFNVWPGDPPLNVSLDSNEGGEGEAHTNELCNAFSEWDEVDVVQNTQIEVPDTQESNQYVKVWLLGNERRRGYPMRTANLLSPAHGGRESLRKALSEKSLVTELLLRQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D412</accession>
    <name>A0AAD9D412_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Helicase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_017014</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000074">
        <property type="protein sequence ID" value="KAK1732314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D412"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005114">
        <property type="entry name" value="Helicase_assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03457">
        <property type="entry name" value="HA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase-associated" evidence="2">
        <location>
            <begin position="247"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="329"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="388"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="462"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="581"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="668" mass="76114" checksum="D2B42F942C5C2825" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6B2</accession>
    <name>A0AAD9D6B2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_013422</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6B2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1735716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="64" mass="7405" checksum="06672C1C4AF458E6" modified="2024-05-29" version="1">MITHSDTFYLCENLKHVDLVDGELHLTIAALQLGEWRNDMYEEIDSINQILPDTPARGLNYDNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6D0</accession>
    <name>A0AAD9D6D0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Heat shock protein 70 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_014482</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6D0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1734609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="358" mass="39131" checksum="8769A474E16D69B9" modified="2024-05-29" version="1">MRRRRRKTDKQSKWSKELAKLEASTSTSSTHNKRIVKKKKKTKMTAKHQNDSQSGGMDALIPSLIGVVVLIVVVMAKMGFRGRATVAGIDLGTTNSVVCVQAPSSGVGEIVCIPDPATNSPVVPSVVSFLDNHHTRNFRTTKEEKEAAPLGMFPHPVDVVVVNHDSVKSLVGEVDYDIISNDESDGDASFSVPYHVPTEDATTITTSTPSSTNVTPSEIGSYIIHHLRTLTRNHLQHDNVHSAVIAIPAKFEPAQRDATIRAFELAGFKVARILEEPTAAALAYGLHKRDDVHYVMVYDFGGGTLDIVYSVAHWLLEQQGGEEIVKAVMASIDKIEASLNNDEEGVTLKTQYRNIARN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6M7</accession>
    <name>A0AAD9D6M7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GTP 3',8-cyclase</fullName>
            <ecNumber evidence="3">4.1.99.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">QTG54_014708</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>GTP + AH2 + S-adenosyl-L-methionine = (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-deoxyadenosine + L-methionine + A + H(+)</text>
            <dbReference type="Rhea" id="RHEA:49576"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.1.99.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.22" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6M7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061799">
        <property type="term" value="F:cyclic pyranopterin monophosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061798">
        <property type="term" value="F:GTP 3',8'-cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21117">
        <property type="entry name" value="Twitch_MoaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013483">
        <property type="entry name" value="MoaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040064">
        <property type="entry name" value="MoaA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000385">
        <property type="entry name" value="MoaA_NifB_PqqE_Fe-S-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010505">
        <property type="entry name" value="MoaA_twitch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050105">
        <property type="entry name" value="MoCo_biosynth_MoaA/MoaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02666">
        <property type="entry name" value="moaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22960:SF0">
        <property type="entry name" value="MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22960">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06463">
        <property type="entry name" value="Mob_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01383">
        <property type="entry name" value="cyclic_pyranopterin_phosphate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01386">
        <property type="entry name" value="main_SPASM_domain-containing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01067">
        <property type="entry name" value="SPASM/twitch_domain_containing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01305">
        <property type="entry name" value="MOAA_NIFB_PQQE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="12 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="15">
        <location>
            <begin position="167"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1734835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="525" mass="58955" checksum="1EB480CF87D5267A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6W5</accession>
    <name>A0AAD9D6W5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_014155</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion inner membrane</location>
            <topology evidence="8">Peripheral membrane protein</topology>
            <orientation evidence="8">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the small Tim family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6W5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050673">
        <property type="entry name" value="Mito_inner_translocase_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13172">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0811">Translocation</keyword>
    <keyword evidence="1 8" id="KW-0813">Transport</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Tim10-like" evidence="9">
        <location>
            <begin position="18"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1735089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="98" mass="11255" checksum="C5B0D7082CE9B0F9" modified="2024-05-29" version="1">MDQVQNLPPHMQSEFMKNMEQMQMKDSLVMYNTLVERCFGTCISSFRSKSLDKYETTCMENCASRYIKMTQRVGLRFAEHQAMQQKRAADAAAAAATN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7I6</accession>
    <name>A0AAD9D7I6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7I6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="178"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="381" mass="42454" checksum="BCE95689E756B9BF" modified="2024-05-29" version="1">MNHNNDDINEACSSLLESPPYRNKEPLPVYRQYGQTSNSQQQQQQQQNKQAPTLPVMCTLISPPTPDKPAAFACSPASTLKHANTTAAAATTTYYTEPQKTKSVSFAPTATVQPINIPKASEMTTQEKQLIWYLGYDYNQFKNNAASDGGVKLVRSMKDSCHFFCIGSFDGSCDEDTSSSSNSGSNHSSDAATAGSSRTSPSGKFYNEHEYNDYVKEDGQEVCKRGLGYHFSRIRKRNRVMTRSAVVAWQKCMQKPSNKQRIEKVVQRKMHATPNLSSSRKNRPQLQQTQSVVLGSVSTKCSRVSREEALWRGNIDFRVAYPERCRFGIVDSIQRKRSSGSAADDVAYHAGKRRRSNECAYSREADGNNSMKVSAARYAQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7S5</accession>
    <name>A0AAD9D7S5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aspartate--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Aspartyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_012024</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Asp) + L-aspartate + ATP = L-aspartyl-tRNA(Asp) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19649"/>
            <dbReference type="Rhea" id="RHEA-COMP:9660"/>
            <dbReference type="Rhea" id="RHEA-COMP:9678"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.12" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7S5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017101">
        <property type="term" value="C:aminoacyl-tRNA synthetase multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04320">
        <property type="entry name" value="AspRS_cyto_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00776">
        <property type="entry name" value="AsxRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000013">
        <property type="entry name" value="Aspartate--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02075">
        <property type="entry name" value="Asp_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004523">
        <property type="entry name" value="Asp-tRNA_synthase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00458">
        <property type="entry name" value="aspS_nondisc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003483">
        <property type="entry name" value="PRK05159.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450:SF1">
        <property type="entry name" value="ASPARTATE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450">
        <property type="entry name" value="ASPARTYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="13">
        <location>
            <begin position="302"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="61"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1737157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="609" mass="68111" checksum="9E59B568B50DF2C5" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7X2</accession>
    <name>A0AAD9D7X2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">IMPACT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012174</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IMPACT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7X2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140469">
        <property type="term" value="P:GCN2-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006446">
        <property type="term" value="P:regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.30">
        <property type="entry name" value="Impact, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023582">
        <property type="entry name" value="Impact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001498">
        <property type="entry name" value="Impact_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036956">
        <property type="entry name" value="Impact_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301">
        <property type="entry name" value="IMPACT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301:SF25">
        <property type="entry name" value="PROTEIN IMPACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01205">
        <property type="entry name" value="Impact_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Impact N-terminal" evidence="2">
        <location>
            <begin position="214"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="325" mass="36544" checksum="9FEA831904C79F35" modified="2024-05-29" version="1">MTVDVLSEEVILRRSEELAALQAYYDDALLPSLIPPSSSEDNRHQATIALEGPWFIQLGNLSLFGLGIPTLEIRLPSSYPFGNECPTPIIHNVMMNPQIKEELLQELQDMYDMELDVGIMWGERCREEISILEETYTTQQQIQQQDDDHRTALKAANDDDNDQEVQTFIPPTTRYNQPIRNFPTCVINNPKYQREILHTPPFHPPKSGAAENMIAHVCEVTCMEHVHWALAELLFNDKKVAKATHNMFAYRFHGDDSTLVHDNDDDGEKGSGTKLASLLELSGAENVLVVVSRWYGGQLLGPARFKWIAGVARTGLVQGGFINGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8A8</accession>
    <name>A0AAD9D8A8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012536</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8A8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026894">
        <property type="entry name" value="DnaJ_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052423">
        <property type="entry name" value="EMIR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44094">
        <property type="entry name" value="DNAJ HEAT SHOCK N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44094:SF8">
        <property type="entry name" value="DNAJ HEAT SHOCK N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14308">
        <property type="entry name" value="DnaJ-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="195"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="587"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="599"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="631" mass="68717" checksum="FE383CB115268080" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D994</accession>
    <name>A0AAD9D994_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">REJ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010822</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D994"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042045016" description="REJ domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="106" mass="10778" checksum="F518870D95A8EBC1" modified="2024-05-29" version="1">MKLLHFLLITLVAGAAAKGSSTGLRGLASASKSGKRSSPTKSSKSSSTKSTKSSTSSSSSSTGCSHSSSSSSSSSCYSSKSNKSSPYTYSSTRSSTRSSKADRKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAQ7</accession>
    <name>A0AAD9DAQ7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_010231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAQ7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1738915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="112" mass="13299" checksum="283542777702FD14" modified="2024-05-29" version="1">MILSKPIPIPQCNRKADHHRDDDVTAHEAQMYEAATWRMYDLICRSRLIRAAHFMDQPQPQAYLVGRPSQHHVVLTQDNDLLLHCLGRNLMMRIKIERILYWNHYPCLAVRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAU3</accession>
    <name>A0AAD9DAU3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_010259</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAU3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006722">
        <property type="entry name" value="Sedlin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04628">
        <property type="entry name" value="Sedlin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1738943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="185" mass="20928" checksum="B027D26F4FFF5C31" modified="2024-05-29" version="1">MSLAAIAVVSRRSGKPLYMRSFVESSDLLFGQYGQNETVGADFFGDILVEESLAQKSSEWSCEENDRLDEMKWKKPGAVGADACWVGLLCSMDSFNAYGYVTTNANYVVIVEDGIAPDNVQLQKSRDVELKTLISYVHRAYTESLLNPFSDINAKITSERFTTMSKAWWLDSIKFEHWFKIFIST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBT4</accession>
    <name>A0AAD9DBT4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoglycerate mutase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009184</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBT4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF61">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="303" mass="33812" checksum="5A18C38B77302A20" modified="2024-05-29" version="1">MRLLRGCYQCLVLHNIIMMKTSSAFASKNILQNTRAAASTTTTTTTSAAKEICETQITSTGTAEVLCTISNEDSRSSLWSEVAINAAKQFTITQRKKLQELGALDVERPVKIVGTSLSENCGLGDCVLEEKKEDGSDMLDNTKIIHFQRHGQGYHNLICDMWRELGKPIDFDSADPNLNPVVRPEFLDPPLTALGMQQCSSQRDLCNSLSPDLVIVSPMLRCIQTAKLSFRDHVSTVPWVSHEGCREELVYWLVTNVDLLQISRQIIPRSTLMILNTMRMCCGMNMVIEGKLSWKSPNGYTSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DC58</accession>
    <name>A0AAD9DC58_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008493</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DC58"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="411" mass="46755" checksum="F4191DFFC0687B76" modified="2024-05-29" version="1">MGNFILERHPTQQQQHPPRFCCDTVVVPLSKSCSISRDFVSTKNITSLPFPIGSRYKDMSLLASEIKTISHIPRKRQIVITHRSRLCANPYVIGRLSGEYVSIVQNWTRLSINDTAETLSQLVGRYNVPSKGKYYLEIIGLLCNDLSWDGEYKHACLEDPSYMKLTDDWAHIYVDSLGANENTLDRDVGIGHWRMSNKVVSMPLQTRYQPEGCHANKDERCLLPMSTDRFDPYQFEFQNQNESSLIQDRVLAVNEANQNILLCFVGLSHAREMAAAVNLWLQKLNTSNIKAVSVDAQFPRFVNRQFIQNNIIGRKCTRTVIAAGQWSVGRIPPGDVKLTCPPQDWRHPAVIDQLNMIIKNLTQSMGVQFIDTSQIIGPMWDAAGDFCHYRNDDISSSEALYMLGRLLPFEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DC90</accession>
    <name>A0AAD9DC90_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">U3 small nucleolar RNA-associated protein 14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_008749</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DC90"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006709">
        <property type="entry name" value="SSU_processome_Utp14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14150">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14150:SF12">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 14 HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04615">
        <property type="entry name" value="Utp14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="234"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="321"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="396"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="470"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="597"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="234"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="247"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="328"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="470"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="484"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="498"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="521"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="601"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="655"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1740654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="750" mass="83990" checksum="F9719B3A22233552" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCA8</accession>
    <name>A0AAD9DCA8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF3007 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008613</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCA8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021562">
        <property type="entry name" value="DUF3007"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35734">
        <property type="entry name" value="OS01G0805200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35734:SF1">
        <property type="entry name" value="OS01G0805200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11460">
        <property type="entry name" value="DUF3007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042008189" evidence="2">
        <location>
            <begin position="25"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="187" mass="20244" checksum="BD003B01F10FC721" modified="2024-05-29" version="1">MARSMLTLCACAIATVMFGHDAAAFAPSAINVQSSATSARQFSTPFTTANSNTFMESGSRTKPTSSSSSLNMMSEKSNLPVFLDPGTKGGAIVLSLILFVIPIVIYQVATGVFGVDEIEAGRDIGVGFSVITMLLWGSTYIFRVATKDMTYAKQLKDYEDAVIAKRLEELDEDEVQALVEDIEREQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCH7</accession>
    <name>A0AAD9DCH7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008131</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCH7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="138"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="464" mass="53832" checksum="4EB4D0A9FA6A1751" modified="2024-05-29" version="1">MTNTAEEVEAVNDQGLKEEEMTDDDDIAAAANSRNEGANDNNMDDTEDFFDWEKIVHEADNGEDDSSSFDMEGVEDVPTDDELLDYVSDDESVLDDWDEQIGMKAKGYKPELPPPNELSEDSRALLFWRHEGEEKSFSDWKIKVEAETTDDDDDCRETNVTIYNVHRLTLAMGPKKSGYFEALLQSDSYSENSDCMSTVKLPKEIAKQFPEFLDYLYAQPLESKFVINFENWKSMKHLANYFLVPRLTEAVAEFIEKDMEDYNLEHMENYISEFHRDISDDMSRRILPKAVLICAELLQSIEVDSPLLMSIPPAMFRSIIRRVQIDEDDNQMALHTCSLIASYLEHNVEDRSVFGIYFCEYLILDPLFYYLDKSEDTAIEFALTWFGLMTKKGWNLEDDDESCFRFLYIERVNRNLSFIIRDYLRSKTPSLEMMERIVRGVPSDIVAKCFRDSVAEARTSRERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDF4</accession>
    <name>A0AAD9DDF4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_005868</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDF4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03749">
        <property type="entry name" value="proteasome_alpha_type_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000016">
        <property type="entry name" value="Proteasome subunit alpha type-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035144">
        <property type="entry name" value="Proteasome_alpha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="7">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="237"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="247"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1743247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="262" mass="28887" checksum="0FA4C3DB4AF76A61" modified="2024-05-29" version="1">MFRNMYDTDVTVWSPEGRLLQVEYAMESVKQGSACIALRSSTHSVIGALKRSVSELSAHQQKILEIDDHLGIGIAGLTADARTLAKWMRNECLNHKYVYGTALPSGRLVTDLADRHQRTTQSYVRRPYGVGLLVASFDKNGPHVYQTCPSGNVYECYATAIGARSQSGRTYLEKHCESFEECSKDDLIMHALKALVGCVSGDGELTRENGSVAIVGKDQKFTLIEGEELQPYLDRLELEGGNNGGNAEEEEDDDGEAEEMET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDM2</accession>
    <name>A0AAD9DDM2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Zf-MYND and TPR domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_006734</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDM2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="6"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="71"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1742169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="296" mass="33059" checksum="EAD48E1B6BF4F3D9" modified="2024-05-29" version="1">MMMFCCAGCGIAEVDDIKLMQCAACDLVRYCSDGCQKDHMPQHKKDCKKRAAELRDEILFKQPESSHDGDCPICLLPLPIDSRKTILTGCCSKVICDGCNFAYIMRECQGSKAPICPFCRHLTDMSKEEYRRNLMKRIEANDPEAMSHKGFDCESEGDYISAFGYYSKATELGYVEAHFSLSGLYREGQGVEKDEKKEVHHLEEAAIGGHPKARHNLGFVELKNGRHARAVKHLIIAAKLGHDMSVDLLKLCYRDGLVSKEDFAAALRGHQAAADATKSPQREAAEAFRKLGFRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDR4</accession>
    <name>A0AAD9DDR4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein-serine/threonine kinase</fullName>
            <ecNumber evidence="8">2.7.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_007623</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + ATP = O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23052"/>
            <dbReference type="Rhea" id="RHEA-COMP:13689"/>
            <dbReference type="Rhea" id="RHEA-COMP:13690"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the PDK/BCKDK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDR4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004740">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010906">
        <property type="term" value="P:regulation of glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16929">
        <property type="entry name" value="HATPase_PDK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.20">
        <property type="entry name" value="Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036784">
        <property type="entry name" value="AK/P_DHK_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018955">
        <property type="entry name" value="BCDHK/PDK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039028">
        <property type="entry name" value="BCKD/PDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947:SF3">
        <property type="entry name" value="[PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10436">
        <property type="entry name" value="BCDHK_Adom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69012">
        <property type="entry name" value="alpha-ketoacid dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="9">
        <location>
            <begin position="385"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1742050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="528" mass="58841" checksum="77E3C8C71E871E05" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEU4</accession>
    <name>A0AAD9DEU4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Potassium-chloride cotransporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_006185</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC12A transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEU4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015377">
        <property type="term" value="F:chloride:monoatomic cation symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000013">
        <property type="entry name" value="Solute carrier family 12 member"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018491">
        <property type="entry name" value="SLC12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004842">
        <property type="entry name" value="SLC12A_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11827:SF72">
        <property type="entry name" value="GH08340P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11827">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03522">
        <property type="entry name" value="SLC12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="185"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="276"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="318"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="369"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="392"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="426"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="9">
        <location>
            <begin position="32"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="SLC12A transporter C-terminal" evidence="10">
        <location>
            <begin position="783"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="626"/>
            <end position="657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1743564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1020" mass="111527" checksum="07B3600E671A1156" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG26</accession>
    <name>A0AAD9DG26_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DG26"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="477"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="494"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="517" mass="58034" checksum="0AF1219151C08839" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG71</accession>
    <name>A0AAD9DG71_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="9">3.6.4.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_004966</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DG71"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47960">
        <property type="entry name" value="DEAD-BOX ATP-DEPENDENT RNA HELICASE 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042104816" evidence="6">
        <location>
            <begin position="23"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="163"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="404"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="36"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="578"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="62"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="84"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="108"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1744433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="631" mass="69685" checksum="6BFA0FCD207D89A8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGA8</accession>
    <name>A0AAD9DGA8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_003273</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGA8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="340" mass="37590" checksum="CD7C9612D45C4589" modified="2024-05-29" version="1">MMSTRKRKAPGSSAIEPPRFISFNMVTRTVSISPPPSQAILSLPSSEDDQHIRGEPSFSSLPHELFCSVVSYLGPTSASLCALHQVNRNHHAKLTTIGNIMLQRAHLRFRTPLPPLSIHESSVSLFVRHARVSKVVHDACEILDSVLKKDFPVINPDDTADEGMKEPSYLDAIVEIDQDTVKPNEVNHALNTALCLLGAGKRHYFEDDPHRADAISESAATSALDWRVFSLCSRIGAKAYKYSKSRMCRRYDHEDYLFSAHYAAVSDEMELDDFSDEEDGEDDDISLDPSEIEIDQDVSLLEKASMVLQLVVLHDAHAAGKHISQVAGSSALNRILSGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGA9</accession>
    <name>A0AAD9DGA9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002734</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGA9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000093">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="1">
        <location>
            <begin position="29"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="299" mass="33716" checksum="D9A33E45356DB68B" modified="2024-05-29" version="1">MRNLSRNTEAVADSLAAMIKRELTTSHSCSCHEGYLNSSDPNLITADDRMKLVDWCYDIVEHCRYSRETVASAMEMVDRFLGMPSNSVDAARVSDEALIDPSKFQLLTVAALYTSIKINEKVAISSDQFAEMCRHVYTAEEIEDMERTMLRGLSWRCHVPTAHQVGLSILSLLLPSVNISEVTWEFLVDEMKYLIELAVRDNYFSTQRASTVALAAILNAISDTRSTEERKVLGAFLRVTMECFDFDHPNQIAAARSKLQSSETLKFDVEDERSLDDSMKTFKVSNRSSAREIVRVISG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGQ6</accession>
    <name>A0AAD9DGQ6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003348</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGQ6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="623"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="759"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="786"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="404"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="825"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="923"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="966"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="48"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="842"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="966"/>
            <end position="989"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1009" mass="115234" checksum="9777BCF9C8E39ACF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DH37</accession>
    <name>A0AAD9DH37_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001529</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asaB hydroxylase/desaturase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DH37"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044053">
        <property type="entry name" value="AsaB-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041278">
        <property type="entry name" value="CmcJ_NvfI_EfuI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598">
        <property type="entry name" value="BLL6449 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598:SF3">
        <property type="entry name" value="OXIDOREDUCTASE AN1597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="373" mass="41171" checksum="087AAB5C8B41B18F" modified="2024-05-29" version="1">MSLAAAGRVVSSTTSSSTSWPQMERPNNDDDGHQSSSSSAVPAIMNYVSAETTEMSTRRDLGGGDSTLVGVIWEPKQVNVHNARMSATEMSLDKNGFELQRSAEDVVGKCQEIDFCSQDDVVDSYYPICETLVENCLKGSASTPTITCVCAFDHNVRSNDHSSVGEIKASQIMTNDVGTAVPQVQNPAGIVHADYTSISGPRRLGDLSQPPKLNDVLRPKLLSQKRSSLLDPSIVQEALDGKRRYAFINVWRSIDQDNPVKDNHLACIDSQTVDKSELRTFKIHYADRVGENYFAFPSSPSNEKQHSWCYYPDMTIEEALFIKQWDSRGNIADGGSERSTFAIHSAFLDPTAPKNAPPRKSIEVRCIVIWDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHI5</accession>
    <name>A0AAD9DHI5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CRAL-TRIO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHI5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="371" mass="42849" checksum="A91E243754A00AC1" modified="2024-05-29" version="1">MSESIITEKLINNILEWATELKHTAREFARLSSHEQAHVWNDLTGDEGRRRTFGTDGKEYFTKGLFEPDDLVEKALKDLDDEIEKLPSDQKGALEKAMQMSKDYVSSNFRLKFLRAEKFDAHLAAEQKLELFGEEKLVREIIQSDLDEDDMASLSSGYLQVLNGLDFGERKVIFYYKALSNIVEHDCYKHRENIFRSFWYVMNVISASEDVQKLGVVNVVYNLGGMPRSGIDYEKSRRLAKLFKAIPVRFCSFYPCIDTKFWTIVVETFSVIINRFLLMRFRIIEGDHEEVMLKLKAVGIPSEVLPVTDESKLLVDDHLKWLARLKMVEEAEALEPPSKRSRAERELKIETFDPESISNLCKNSLSCYTVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHI8</accession>
    <name>A0AAD9DHI8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Oxidation resistance protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_003722</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OXR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHI8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006571">
        <property type="entry name" value="TLDc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354:SF62">
        <property type="entry name" value="MUSTARD, ISOFORM V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354">
        <property type="entry name" value="NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07534">
        <property type="entry name" value="TLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00584">
        <property type="entry name" value="TLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51886">
        <property type="entry name" value="TLDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TLDc" evidence="5">
        <location>
            <begin position="374"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1745798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="631" mass="68927" checksum="3A332938FA400EBC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DK00</accession>
    <name>A0AAD9DK00_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heat shock protein 90 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_000499</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DK00"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16927">
        <property type="entry name" value="HATPase_Hsp90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.80:FF:000007">
        <property type="entry name" value="Heat shock protein 90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000054">
        <property type="entry name" value="Heat shock protein 90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11260:FF:000005">
        <property type="entry name" value="Heat shock protein 90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="entry name" value="Heat shock protein 90, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00505">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019805">
        <property type="entry name" value="Heat_shock_protein_90_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003555">
        <property type="entry name" value="PRK05218.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110942">
        <property type="entry name" value="HSP90 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00298">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042270226" evidence="6">
        <location>
            <begin position="20"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="157"/>
            <end position="158"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="178"/>
            <end position="183"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="421"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR002583-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1748560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="751" mass="84752" checksum="CF5B7DAF30E1F7D1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DK37</accession>
    <name>A0AAD9DK37_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000619</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DK37"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042179769" evidence="2">
        <location>
            <begin position="23"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="220" mass="24862" checksum="BD27F8AE872C708D" modified="2024-05-29" version="1">MKHGTSRTTMVLTICTLFRLQAYERPNRQVETFSTRKVEVDRKEDITISDVKEALLAVRKVESGNTEQEQSTISRRPTSSGVLDTATQTNHEVPTRKNRTRRQTVIGNVAMFGAMLKPVSKSNTKNNYESQEGNHLDSSIDGNESKKKAPNQRRKTIMEGISPFVGMRKDPVEKTADTPTHDDRKAIRISREDGNVDIERECRKLYGLYGDLDCFSSHSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-12-02" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6U3ZP78</accession>
    <name>A0A6U3ZP78_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DNA-directed RNA polymerase II subunit RPB7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_007363</name>
        <name evidence="8" type="ORF">SMAR0320_LOCUS24359</name>
        <name evidence="9" type="ORF">SMAR0320_LOCUS24360</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="HBGZ01033960">
        <property type="protein sequence ID" value="CAD9633279.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="HBGZ01033961">
        <property type="protein sequence ID" value="CAD9633281.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6U3ZP78"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003727">
        <property type="term" value="F:single-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060213">
        <property type="term" value="P:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045948">
        <property type="term" value="P:positive regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000043">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.120:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.120">
        <property type="entry name" value="RNA polymerase Rpb7-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036898">
        <property type="entry name" value="RNA_pol_Rpb7-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045113">
        <property type="entry name" value="Rpb7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005576">
        <property type="entry name" value="Rpb7-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709:SF4">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II, III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03876">
        <property type="entry name" value="SHS2_Rpb7-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88798">
        <property type="entry name" value="N-terminal, heterodimerisation domain of RBP7 (RpoE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb7-like N-terminal" evidence="7">
        <location>
            <begin position="9"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="81"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CAD9633279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CAD9633281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1741790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="182" mass="20493" checksum="8CE13E08F5B14A8B" modified="2020-12-02" version="1">MFYVKVLEHEIELEPIHFGQKLRATIVRLLKEEVEGLALANYGFVVNVIEVKEDQIRSGIIEYDTGNVVFYVKYTALLLRPFINEVVDATVAQCNELGFFAYVGPLRIFVSKHSMQEDMFNGFDGERDSWVSDDKEVVISSGCGVRLKIKGRTVEHGNITAIGTIKDNYLGLIELPSEAEAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1H0D7</accession>
    <name>A0A8K1H0D7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Iron-sulfur cluster formation ABC transporter ATP-binding subunit</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Sulfate ABC transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">sufC</name>
        <name evidence="4" type="ORF">QTG54_017243</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="5"/>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2021" name="Front. Plant Sci." volume="0" first="0" last="0">
            <title>Chloroplast Genomes for Five Skeletonema Species: Comparative and Phylogenetic Analysis.</title>
            <authorList>
                <person name="Liu S."/>
                <person name="Xu Q."/>
                <person name="Liu K."/>
                <person name="Zhao Y."/>
                <person name="Chen N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CNS00100</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MW679506">
        <property type="protein sequence ID" value="UAM91442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_010200956.1">
        <property type="nucleotide sequence ID" value="NC_058701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1H0D7"/>
    <dbReference type="GeneID" id="68638098"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03217">
        <property type="entry name" value="ABC_FeS_Assembly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010230">
        <property type="entry name" value="FeS-cluster_ATPase_SufC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01978">
        <property type="entry name" value="sufC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43204">
        <property type="entry name" value="ABC TRANSPORTER I FAMILY MEMBER 6, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43204:SF1">
        <property type="entry name" value="ABC TRANSPORTER I FAMILY MEMBER 6, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="3">
        <location>
            <begin position="8"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1732200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="UAM91442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="251" mass="28184" checksum="CDEA31ABBCB1402D" modified="2022-08-03" version="1">MTLDSPILEIKNLRACIDNNEILKNLNLTINRGEIHAIMGPNGSGKSTFSKIIAGHPAYQVLGGDILFKGSSILDLDPEKRSHLGIFLAFQYPIEIPGVSNEDFLRLAYNSKQKFLNKPEVDPIEFFSIINEKLKLVSMSSVFLSRNVNEGFSGGEKKRNEILQMILLESELSILDETDSGLDIDALKIISNGINTFMDSDKAIILITHYQRLLDYIKPDFVHVMQNGKIIKTGNSELAKELELKGYEWLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRF9</accession>
    <name>A0AAD8XRF9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein-serine/threonine phosphatase, PP2C family</fullName>
            <ecNumber evidence="7">3.1.3.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_016962</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000072">
        <property type="protein sequence ID" value="KAK1732332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRF9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47992">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042137220" evidence="3">
        <location>
            <begin position="26"/>
            <end position="1198"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="384"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="856"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="6">
        <location>
            <begin position="906"/>
            <end position="1198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="193"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="119"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1732332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1198" mass="134803" checksum="A70978C5C1E98457" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XS73</accession>
    <name>A0AAD8XS73_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Protein-serine/threonine phosphatase, PP2C family</fullName>
            <ecNumber evidence="14">3.1.3.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_016402</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="14"/>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XS73"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF127">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C AND CYCLIC NUCLEOTIDE-BINDING_KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00103">
        <property type="entry name" value="CAMPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 10" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="13">
        <location>
            <begin position="47"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="12">
        <location>
            <begin position="487"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="12">
        <location>
            <begin position="620"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="252"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="255"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1732864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="737" mass="80984" checksum="C416CAF23E499FEE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSM2</accession>
    <name>A0AAD8XSM2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WRKY transcription factor 19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016623</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000061">
        <property type="protein sequence ID" value="KAK1732646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSM2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="232" mass="24062" checksum="0A07A8584F0F1342" modified="2024-05-29" version="1">MNEEEDLAVLIYKSSKTAKARAAAAAAAAKEKGHSSTERRTSTRKRSSASVNQDFEPSADGSRKQKVRSICSAAQCTNIAMKGVLSMKGGVCNRHGAKKKRCSSEGCMNLAAKGGVCRRHGAGLKLCSSTGCPNLAMRGGVCGRHGAKKKRCSSEGCINRAQQGGVCMKHGAAVKSCSSAGCPNRVVKGGVCVRHGAKKKRCSSTGCMNQSQSGGVCKRHGAELKSTADAQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSN9</accession>
    <name>A0AAD8XSN9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Eukaryotic translation initiation factor 2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_016480</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat EIF2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000057">
        <property type="protein sequence ID" value="KAK1732768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSN9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011387">
        <property type="entry name" value="TIF2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013979">
        <property type="entry name" value="TIF_beta_prop-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13227">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13227:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08662">
        <property type="entry name" value="eIF2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Translation initiation factor beta propellor-like" evidence="8">
        <location>
            <begin position="278"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1732768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="371" mass="39722" checksum="11AADA6E3E255C28" modified="2024-05-29" version="1">MSSPQRPIQLLFRSKDGVELYTLADTSSSAAPSSKPSQRGQTLYAGKTTFHLLSPNGSAAFIHDASVGLIKCDLSSTTTTSAASTATTPFLQNSKAIQLAKCSPRGSYLLTWERPSKLDDNNNNNGNLKVWSAANGALLQSFSCKKATLETVQWTHDEQCVFHCVTNEIHIYAANDWKRVGKVRSQGVASFSLPTHKGIDPNAATTAAAAVKSGEEKKKYLLTTFVPGIKGKPARVDMFRYPDRMGRDSSSTVVDNDSSNSDDKTVVNIPSGPGLTSKSLFNAEEVNVKWSPRADAALLLTQTAVDNTGQSYYGSTHLFLLLEKDVKNPTVGSAMVVPLPKEATKDGSGTVPIVSADWIPNPSITGVVPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSY0</accession>
    <name>A0AAD8XSY0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">leucine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Leucyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">QTG54_016441</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Leu) + L-leucine + ATP = L-leucyl-tRNA(Leu) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11688"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSY0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07958">
        <property type="entry name" value="Anticodon_Ia_Leu_BEm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00812">
        <property type="entry name" value="LeuRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000012">
        <property type="entry name" value="Leucine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000077">
        <property type="entry name" value="Leucine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000011">
        <property type="entry name" value="Leucine--tRNA ligase chloroplastic/mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="entry name" value="Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00049_B">
        <property type="entry name" value="Leu_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002302">
        <property type="entry name" value="Leu-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025709">
        <property type="entry name" value="Leu_tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00396">
        <property type="entry name" value="leuS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740:SF2">
        <property type="entry name" value="LEUCINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740">
        <property type="entry name" value="LEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13603">
        <property type="entry name" value="tRNA-synt_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00985">
        <property type="entry name" value="TRNASYNTHLEU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10 16" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041929168" description="leucine--tRNA ligase" evidence="11">
        <location>
            <begin position="17"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Leucyl tRNA synthetase" evidence="14">
        <location>
            <begin position="134"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Leucyl-tRNA synthetase editing" evidence="15">
        <location>
            <begin position="315"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="12">
        <location>
            <begin position="723"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="13">
        <location>
            <begin position="800"/>
            <end position="911"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF13603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1732903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="950" mass="106964" checksum="62DF0F24A30E5DC8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTU4</accession>
    <name>A0AAD8XTU4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rossmann-fold NAD(P)-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015912</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000050">
        <property type="protein sequence ID" value="KAK1733353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTU4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05243">
        <property type="entry name" value="SDR_a5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020">
        <property type="entry name" value="FLAVIN REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020:SF11">
        <property type="entry name" value="OS06G0360300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="1">
        <location>
            <begin position="112"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="954" mass="103946" checksum="E5018AC330C92AEC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XU41</accession>
    <name>A0AAD8XU41_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Vacuolar transporter chaperone 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_015888</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000049">
        <property type="protein sequence ID" value="KAK1733473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XU41"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006799">
        <property type="term" value="P:polyphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07751">
        <property type="entry name" value="PolyPPase_VTC4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14447">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.100.30">
        <property type="entry name" value="VTC, catalytic tunnel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051572">
        <property type="entry name" value="VTC_Complex_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018966">
        <property type="entry name" value="VTC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042267">
        <property type="entry name" value="VTC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140:SF1">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE COMPLEX SUBUNIT 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09359">
        <property type="entry name" value="VTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="643"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="675"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="715"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="9">
        <location>
            <begin position="2"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="42"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="88"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1733473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="748" mass="84881" checksum="CFC529000556876F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUW4</accession>
    <name>A0AAD8XUW4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015086</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000040">
        <property type="protein sequence ID" value="KAK1734319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUW4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="300"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="537" mass="62429" checksum="42BBB905908659DF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV61</accession>
    <name>A0AAD8XV61_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000040">
        <property type="protein sequence ID" value="KAK1734273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV61"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="109"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="144"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="181"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="199"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="260" mass="28177" checksum="85A8907DA8925334" modified="2024-05-29" version="1">MAMMMAQHRHDDSDSHDSSHDSGNEEKSSRVRVADADLRRSIGSTSSNSTEEGSSSTNNEDKNSSSSSKQRRPRRKGRAADLEFRRSATFTRRHPSPEPEETTSKEESSSQQPSQSSSSGDNKAALRRRKKCQPRHRCASVNESVSSILKPSKYSSSSSSTIHPLSSSKGGGSDDNTVTIAATSSPTAAAKKSSRFLRRGSSSSSNEGLPSASMHSFFLPPLEKPLNKSQKRPSCDSLDGQWVANGVDFSSSVEVHVFHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVJ6</accession>
    <name>A0AAD8XVJ6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014537</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVJ6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="181" mass="18918" checksum="79728ABC5DF7BCD0" modified="2024-05-29" version="1">MDAATLKAQRQIGSAPSTKSSKSKRNKKRRSKKSSQSAGQPSGPGNTAASLERSRRRQSDRFGDASSRESGADMKGKCTSRTLGALHTIDAGLGLACIVYGGMAHVVSVTALSVTYGLVLFIGAIAGAIGYYSEGCNKRGLTASAIAGLLTCLADIAAFVFVIISWGSFTTFLKEMPKRCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVS9</accession>
    <name>A0AAD8XVS9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Chlorophyll a/b binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014914</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVS9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="201" mass="20849" checksum="F089DFD4122115E6" modified="2024-05-29" version="1" fragment="single">DLLVNHKSENSKHGSTAVVQLNGTLLKLGLFIKVIPAEVNVSVTEVTNVLVSSSRNITHEGNLQPSNEGDDLALSLEGDGIRSDQGGNSVGEGVEGISGVVDVSGEVDSGTGHNLAKEGKLSDTSVLDLNITETVETFLGNVSGEQAEGIEESKRRLDTELILEGVQGGGGGLVLGRAKAAAEPIRAAMMADFMMDVVMIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWG5</accession>
    <name>A0AAD8XWG5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">60S ribosomal export protein NMD3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_014576</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the NMD3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWG5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039768">
        <property type="entry name" value="Nmd3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007064">
        <property type="entry name" value="Nmd3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048898">
        <property type="entry name" value="OB_NMD3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12746:SF2">
        <property type="entry name" value="60S RIBOSOMAL EXPORT PROTEIN NMD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12746">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04981">
        <property type="entry name" value="NMD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21192">
        <property type="entry name" value="OB_NMD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nmd3 N-terminal" evidence="9">
        <location>
            <begin position="41"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="60S ribosomal export protein NMD3 OB-fold" evidence="10">
        <location>
            <begin position="203"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="315"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="421"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="332"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="429"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1734703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="440" mass="49093" checksum="ED39F4FA7B9F6227" modified="2024-05-29" version="1">MMFPSNNVSKLNSLSDGRSVQTAPKKLDKAHGQLLFNSAKRETTHARVLLILELAIARNALMRKHILSVQTKKAGFDFYFPTPDKARHFTQYLSKVAPMRIKTTQSLVSEDKTNNTANVRHTLACEMVPLCRDDLVVIGKQAKGAGKLTGKLCLVLRVSSAVRLITVSPSREFDVASQCTELHSDTYWRGESSYRLFLSSRRLVRFVVLDVELCDDERDRYNSGDSDQVYEGPQSGVSKYALADVEVARETDFGVNDETFMCVTHLGHLLSPGDVVLGYDLASTVLSSEAEFSIENDVTSNFVMPDIVLVKKIKGGQDQSRVEGGDDSAESKHKKGKAKSSGSKKRDRRMKKEEQKQQKLAAAAARMGLNTDEDVYFDEDDFIDGEGNTISEAVQKENEKFEKEVEMDEDLADDLALVEAEFREQSFSDNEDDESEKVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWH6</accession>
    <name>A0AAD8XWH6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">rRNA small subunit methyltransferase G</fullName>
            <ecNumber evidence="6">2.1.1.170</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_014237</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.170" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWH6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070043">
        <property type="term" value="F:rRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00074">
        <property type="entry name" value="16SrRNA_methyltr_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003682">
        <property type="entry name" value="rRNA_ssu_MeTfrase_G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31760">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31760:SF0">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02527">
        <property type="entry name" value="GidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042000371" evidence="5">
        <location>
            <begin position="23"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="358"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="387"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1735171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="407" mass="46301" checksum="1DB797D9476E832B" modified="2024-05-29" version="1">MWTQHKMTLPIMMMACISHVHPLLTRRTMMTTAFSFSSTNSAITTATRGGIRKQHYPYLTNNSQALLHAISTTTSSEEEEEVWNRAAEEIDPYSEEAKLNLSNFYKRHNIVLDAEKDHKKLLRLTEQVLSWNQRLNLISRKDCTPEVVYHRHILPSIALLPLVLKSSHDTDDDTNNNNNSQPLKIVDVGTGGGFPGLPLALLLPHCEFTLVDSIQKKLVAVSEMAAELDVENVRIHCGRCEEMYAEREGRMEHLGKYDVCLGRSVTALPRFCAWMYPLLKMQQQQQEEDGDGEEGRLIYIIGGELEDVVESRILSDTNLDELLDREEGTSDKRALIFMANDVEEIAVESGEVDKIVRHAPAGTGKKSKKKKNQQQQRTNKVAKGAWQKRDNSVKKERGYGDFQRFEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XX61</accession>
    <name>A0AAD8XX61_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF2214 domain-containing membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_013712</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XX61"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018706">
        <property type="entry name" value="DUF2214_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09980">
        <property type="entry name" value="DUF2214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042215652" evidence="3">
        <location>
            <begin position="16"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="160"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1735549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="275" mass="29243" checksum="D8C905F8B7BC6BEB" modified="2024-05-29" version="1">MRLTALLSLFAAATAWAPQPRTTIKSSSSTSAPQSFDPLNLSDETSSSSPVRPEAVFLASALPIVANPSVASAATAGAPNAVGSAFAAYGHYISMIGILACIMAERLTIKPNMSEEEEDFIAAADIGLGVWGVGIAYSGYLRAVEYEKGFDFYAHEPLFWLKIAFVGVFGASSFFNTVVIIQRAIAKRNGNFTPMGEKLSNRMIRICNAELTAIAIIPLTATFMARGVGYSQDIPWQAEAALAALVFGGLSFKYIKEALTFEDNPVSLTSSASED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXG9</accession>
    <name>A0AAD8XXG9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013651</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXG9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11393">
        <property type="entry name" value="bHLH_AtbHLH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045239">
        <property type="entry name" value="bHLH95_bHLH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="2">
        <location>
            <begin position="503"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="234"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="422"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="444"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="472"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="771" mass="79342" checksum="053265BBFA15FEC0" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXI8</accession>
    <name>A0AAD8XXI8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cation diffusion facilitator family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_013681</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXI8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050681">
        <property type="entry name" value="CDF/SLC30A"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11562">
        <property type="entry name" value="CATION EFFLUX PROTEIN/ ZINC TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11562:SF17">
        <property type="entry name" value="RE54080P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0864">Zinc transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="53"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="252"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="11">
        <location>
            <begin position="52"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="12">
        <location>
            <begin position="314"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="191"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="18"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="192"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1735518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="402" mass="43359" checksum="373BCF9A913E7987" modified="2024-05-29" version="1">MGHDHSHGHSHGHTGSSHCDEEGGGHNHEEKVKKPAGTTEQERRHEVIRKLKTASALCFTFFLVEVIGGFLAGSLAVLSDAAHLAADLSAFVVAILGSHIAALPASEAHTFGLKRTESLAALFSMVSLAILSVGLAIEALRRMYFILQGGEDIQPVNGKLMSQIAFIGVIVNVILAYVLGEDHVHMVGSDTGCDHGGHDHSHGHGHSHGHGHEETDSLVSPKKGGYASVSEAQHTDEIVAADHERNVNLHAAYLHVLADLAQSVIVFVAGLIIWYKPTWQITDPICTLIFSILVCWSTVSVIRSSLSVLLEEVPPGVQYDEVFDAIKNVTGVSNVHDLHIWSISHGQSCLSVHAAAEDIESAYRDITRLCHKRKITHLTIQLQPATTPDCVTCVDGSDHQCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYJ6</accession>
    <name>A0AAD8XYJ6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dynein axonemal assembly factor 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_013519</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYJ6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052623">
        <property type="entry name" value="DAAF5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16216">
        <property type="entry name" value="DYNEIN ASSEMBLY FACTOR 5, AXONEMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16216:SF2">
        <property type="entry name" value="DYNEIN AXONEMAL ASSEMBLY FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1735813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="969" mass="105898" checksum="74FD543317619EFB" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYQ4</accession>
    <name>A0AAD8XYQ4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Thioredoxin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_013220</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYQ4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09212">
        <property type="entry name" value="PUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02956">
        <property type="entry name" value="ybbN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036339">
        <property type="entry name" value="PUB-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018997">
        <property type="entry name" value="PUB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45663">
        <property type="entry name" value="GEO12009P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45663:SF11">
        <property type="entry name" value="GEO12009P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09409">
        <property type="entry name" value="PUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00580">
        <property type="entry name" value="PUG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143503">
        <property type="entry name" value="PUG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0249">Electron transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="UBA" evidence="6">
        <location>
            <begin position="222"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="7">
        <location>
            <begin position="312"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="729"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="590"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="307"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="736"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="769"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="785"/>
            <end position="805"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1736084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="805" mass="87373" checksum="7E5FF69790190492" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZ27</accession>
    <name>A0AAD8XZ27_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012849</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZ27"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="213" mass="23312" checksum="CA9FA89DC5C0344C" modified="2024-05-29" version="1">MVTLGWETYSFGADVFGATAFLLTLVGSARCDFIKFTSVDGTFTDHFGVWRYGQWAFLSNGQQAWLYEGCFPYADSVVIDSKWKAARAFDAMVLIGGLLFFMMSAFSACLGKRTYTRPNGIVGVCLLLLSLFSGLTLLVLDSNLCKNNVLLGELFQFLFNDQCELSTGANCFISATVFWFAAALCSLSASRSKSEENDEVEGGLTESLIQGEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZX8</accession>
    <name>A0AAD8XZX8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">1,4-dihydroxy-2-naphthoyl-CoA synthase</fullName>
            <ecNumber evidence="5">4.1.3.36</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_012970</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-succinylbenzoyl-CoA + H(+) = 1,4-dihydroxy-2-naphthoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:26562"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57364"/>
            <dbReference type="ChEBI" id="CHEBI:58897"/>
            <dbReference type="EC" id="4.1.3.36"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.36" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZX8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008935">
        <property type="term" value="F:1,4-dihydroxy-2-naphthoyl-CoA synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01934">
        <property type="entry name" value="MenB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010198">
        <property type="entry name" value="DHNA-CoA_synthase_MenB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43113:SF1">
        <property type="entry name" value="1,4-DIHYDROXY-2-NAPHTHOYL-COA SYNTHASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43113">
        <property type="entry name" value="NUCLEOSIDE-DIPHOSPHATE-SUGAR EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1736370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="319" mass="34549" checksum="B78987DB4B1A5E5C" modified="2024-05-29" version="1">MGDSSNADPASMAATRSSSKTAPPTPKRDGFHLVPSHPITYDVDQGSGFQDITYHVSTSDHCARIAFNRPHVLHAFRPTTINEVRQALELAQDDTRVSVIVLSSNLIEERTPAFCAGGDQSVRSSDGGYDDGSEAAPRLRVLDLQIQMRRCFKPIVAVVRGYAIGGGHILHMCADLTLAGEDAVFGQVGPRMGSVDAGYGSVHLARMVGQKKAREIWFLCKYYSAEEALQMGLINGVFPNAKLEGEVGRWVRRMGMLSPTALAVAKAAINADQDGSAGISLMGGHITRLFYMSEEAKEGRDAYLSGRPPQFRKIPQSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y014</accession>
    <name>A0AAD8Y014_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Adenine DNA glycosylase</fullName>
            <ecNumber evidence="4">3.2.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">QTG54_012811</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolyzes free adenine bases from 7,8-dihydro-8-oxoguanine:adenine mismatched double-stranded DNA, leaving an apurinic site.</text>
            <dbReference type="EC" id="3.2.2.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nth/MutY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.31" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y014"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034039">
        <property type="term" value="F:8-oxo-7,8-dihydroguanine DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035485">
        <property type="term" value="F:adenine/guanine mispair binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032357">
        <property type="term" value="F:oxidized purine DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000701">
        <property type="term" value="F:purine-specific mismatch base pair DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.30:FF:000002">
        <property type="entry name" value="Adenine DNA glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="entry name" value="Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044298">
        <property type="entry name" value="MIG/MutY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42944">
        <property type="entry name" value="ADENINE DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42944:SF1">
        <property type="entry name" value="ADENINE DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00633">
        <property type="entry name" value="HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13 16" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="9 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="15">
        <location>
            <begin position="229"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="47"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="127"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="60"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="139"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="163"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="189"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1736789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="676" mass="74517" checksum="7D1B354AE5A088F4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y042</accession>
    <name>A0AAD8Y042_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_012720</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y042"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06174">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044770">
        <property type="entry name" value="MFS_spinster-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23505:SF79">
        <property type="entry name" value="PROTEIN SPINSTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23505">
        <property type="entry name" value="SPINSTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="315"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="353"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="386"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="416"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="449"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="473"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="537"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="572"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="605"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="702"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="314"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="100"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="204"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="122"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1736698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="832" mass="90184" checksum="5885DCD57681188D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y072</accession>
    <name>A0AAD8Y072_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_012508</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1737063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y072"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17963">
        <property type="entry name" value="DEADc_DDX19_DDX25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 7 13" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="12">
        <location>
            <begin position="155"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="188"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="389"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="78"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="6">
        <location>
            <begin position="155"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="23"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1737063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="550" mass="60629" checksum="6F7DD516D427B664" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0A5</accession>
    <name>A0AAD8Y0A5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Chloroquine-resistance transporter-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_012339</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CRT-like transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0A5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013936">
        <property type="entry name" value="CRT-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31326">
        <property type="entry name" value="PROTEIN CLT2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31326:SF1">
        <property type="entry name" value="PROTEIN CLT2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08627">
        <property type="entry name" value="CRT-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="216"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="245"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="400"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="458"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="485"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="517"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="76"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="44"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1736894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="631" mass="69590" checksum="7056C75292B93579" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1L7</accession>
    <name>A0AAD8Y1L7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011809</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1L7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="141" mass="16414" checksum="8486D6594DDBC4D3" modified="2024-05-29" version="1">MMAEEKKDDHHHDGWLDDEMKSIQWPIDKSEQIEISLKQAAQSFFASSATETATTNDDDVLQSCINNQSVSIEPFLISIRRVLHRYPELMYQERMTSQIVQRLLTDMGITNYTVGWAKNIHSKYYNPSTGKLYRLQKRGTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1T3</accession>
    <name>A0AAD8Y1T3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">AP-1 complex subunit mu-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_011227</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the adaptor complexes medium subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1T3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09250">
        <property type="entry name" value="AP-1_Mu1_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14835">
        <property type="entry name" value="AP1_Mu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000002">
        <property type="entry name" value="AP-2 complex subunit mu, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050431">
        <property type="entry name" value="Adaptor_comp_med_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001392">
        <property type="entry name" value="Clathrin_mu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018240">
        <property type="entry name" value="Clathrin_mu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10529">
        <property type="entry name" value="AP COMPLEX SUBUNIT MU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005992">
        <property type="entry name" value="Clathrin_mu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00314">
        <property type="entry name" value="CLATHRINADPT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00990">
        <property type="entry name" value="CLAT_ADAPTOR_M_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00991">
        <property type="entry name" value="CLAT_ADAPTOR_M_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="6">
        <location>
            <begin position="186"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1737933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="458" mass="51586" checksum="6236DAB8A78ADE18" modified="2024-05-29" version="1">MVASAIFITDLTGKPLISRNYRGDIPLTSSIETFARYLIEVEEDVKTPVFHVDSAGEFVGREDVGCTGVGGEAFVYVQHNNLYLCGVTCKNSNIALILTYLYQLTALFQDYFTTLNEESIRDNFVIIYELLDETMDHGLPQSLDSTILRQFITQEGNRMADDSKNKPPVALTNAVSWRAEGIKHKKNEIFLDVVEKLNLLVAANGTVLHCEINGAVKMKSFLSGMPELKLGLNDKVMFEASGRNQQARGGKSVELEDIKFHQCVRLARFENDRTISFIPPDGEFDLMTYRLDTQVKPLIWVEAVVEPHKGSRIEYMIKTRSQFKSRSVANNVEISIPVPPDVDSPSFKSSVGNVTYLPDKDCVVWTIKQFHGGREYLMRAHFGLPSITRDEADAANKGMGSGMDMSWKKPIGVKFEIPYFTVSGIQVRYLKIIERSGYQALPWVRYITANGDYQLRMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1W3</accession>
    <name>A0AAD8Y1W3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011798</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1W3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042112415" evidence="2">
        <location>
            <begin position="30"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="140"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="164"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="213" mass="23971" checksum="721798089AC92015" modified="2024-05-29" version="1">MTKTTIHKRPMQAAAAYFLLLSFLVIVMASTSCSSVHAFASHNNSLLNNNRPLHYDSGSSRLDTSVAYTSTPFDVGNNNDLWQLLEELRNKNDNSPSSDEAFQRAIDSLYRESQFNIHNLEKEIEVLRQKLDEPTTANDSNNGSSFSFQESFQTTTQDDDDNSKYNGSSSGSSSNMDVDEISNKLLKAVFVGYQWTEDDKKRLSSAHPQDHQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2G2</accession>
    <name>A0AAD8Y2G2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UmuC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2G2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050116">
        <property type="entry name" value="DNA_polymerase-Y"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11076:SF33">
        <property type="entry name" value="DNA POLYMERASE KAPPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11076">
        <property type="entry name" value="DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UmuC" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="137" mass="15675" checksum="AA05A4851869456B" modified="2024-05-29" version="1">MISTSNYVARKYGVRAAMPGYLGSTLVKEISEGKETLTFVKSDFKLYKRKSAEVKAILEEYDPKLKMYSLDEAYMDMMPYLEVKMSNNTMTHEAITKHLNTTASNNNLKAQLPLHEDFLTLPSTQTFKIFSTPFVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3E0</accession>
    <name>A0AAD8Y3E0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Kringle domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_010737</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3E0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004175">
        <property type="term" value="F:endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005102">
        <property type="term" value="F:signaling receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00108">
        <property type="entry name" value="KR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.20.10">
        <property type="entry name" value="Plasminogen Kringle 4"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000001">
        <property type="entry name" value="Kringle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013806">
        <property type="entry name" value="Kringle-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018056">
        <property type="entry name" value="Kringle_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038178">
        <property type="entry name" value="Kringle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050759">
        <property type="entry name" value="Serine_protease_kringle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24261:SF7">
        <property type="entry name" value="KRINGLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24261">
        <property type="entry name" value="PLASMINOGEN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00051">
        <property type="entry name" value="Kringle"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00018">
        <property type="entry name" value="KRINGLE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00130">
        <property type="entry name" value="KR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57440">
        <property type="entry name" value="Kringle-like"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00021">
        <property type="entry name" value="KRINGLE_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50070">
        <property type="entry name" value="KRINGLE_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0420">Kringle</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042278956" evidence="5">
        <location>
            <begin position="16"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1203"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="domain" description="Kringle" evidence="6">
        <location>
            <begin position="41"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Kringle" evidence="6">
        <location>
            <begin position="277"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="Kringle" evidence="6">
        <location>
            <begin position="419"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="Kringle" evidence="6">
        <location>
            <begin position="661"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="domain" description="Kringle" evidence="6">
        <location>
            <begin position="803"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="domain" description="Kringle" evidence="6">
        <location>
            <begin position="943"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="domain" description="Kringle" evidence="6">
        <location>
            <begin position="1097"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="326"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="501"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="656"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="710"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="276"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="326"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="336"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="710"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="720"/>
            <end position="788"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1738707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1268" mass="136645" checksum="952E82F281574D1D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3M2</accession>
    <name>A0AAD8Y3M2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Prostaglandin G/H synthase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_010550</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3M2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004666">
        <property type="term" value="F:prostaglandin-endoperoxide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050783">
        <property type="entry name" value="Oxylipin_biosynth_metab"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903">
        <property type="entry name" value="PROSTAGLANDIN G/H SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903:SF39">
        <property type="entry name" value="PROSTAGLANDIN G_H SYNTHASE 2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00457">
        <property type="entry name" value="ANPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="376"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR619791-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1738520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="585" mass="66006" checksum="8DB0E584FAF8C895" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3R0</accession>
    <name>A0AAD8Y3R0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011404</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3R0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="497"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="512"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="524" mass="57396" checksum="9D5A3A332FA925B2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y414</accession>
    <name>A0AAD8Y414_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cell division control protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010694</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y414"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050311">
        <property type="entry name" value="ORC1/CDC6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763:SF26">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase AAA-type core" evidence="1">
        <location>
            <begin position="27"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="330" mass="36902" checksum="9F3EB37A11D1E679" modified="2024-05-29" version="1">MASHAAMSIDAIKKEMFKSMAKKLEIEKNSSPTVFLNQFRKKGMILVVDEIDMLFKNQGGSAEEWFSTLIEWCEDKELPFSMIGISNSVNDINATTIRELSNTPHELVFPTYNEEDLLAILEKRIGKKIVDTKALQLIAKRVAASTGDARKALEITSNAVDKALDACTEKWLEEVEADSYPLVKMPQMMRAIREGMPTRHEEIIRGLPQAAKVILCIAVSLGKVWGPTAAVSIATLKKYACQATQHAMLDEASLGQITNLVEMLMDSGLLTTDHDGCFNFNANDHSSRLHIGVQLDDVEIALEKSLLEESSFYRSLVDYVKRECPRPEYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4D9</accession>
    <name>A0AAD8Y4D9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Beta-hydroxyacyl-ACP dehydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010163</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4D9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013114">
        <property type="entry name" value="FabA_FabZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30272">
        <property type="entry name" value="3-HYDROXYACYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30272:SF1">
        <property type="entry name" value="3-HYDROXYACYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07977">
        <property type="entry name" value="FabA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="72" mass="7806" checksum="5F307DF0F0F962BD" modified="2024-05-29" version="1" fragment="single">LTGTGRIFSLEGINGILPHLYPFLLVDKVVENKQGKRAVGIKAVTAKEAHFTGHFPDRPIMHGVLQPSCVQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4V7</accession>
    <name>A0AAD8Y4V7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rhodanese-related sulfurtransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_009372</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4V7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022111">
        <property type="entry name" value="Rhodanese_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002935">
        <property type="entry name" value="SAM_O-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040503">
        <property type="entry name" value="TRHO_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43846:SF1">
        <property type="entry name" value="TRNA URIDINE(34) HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43846">
        <property type="entry name" value="UPF0176 PROTEIN YCEA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01596">
        <property type="entry name" value="Methyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12368">
        <property type="entry name" value="Rhodanese_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17773">
        <property type="entry name" value="UPF0176_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51682">
        <property type="entry name" value="SAM_OMT_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="6">
        <location>
            <begin position="484"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1739613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="975" mass="108263" checksum="3A0D7BE95B4A4C22" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5M1</accession>
    <name>A0AAD8Y5M1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cyanate hydratase</fullName>
            <shortName evidence="3">Cyanase</shortName>
            <ecNumber evidence="3">4.2.1.104</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Cyanate hydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Cyanate lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CYN</name>
        <name evidence="5" type="ORF">QTG54_010401</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 3">Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>cyanate + hydrogencarbonate + 3 H(+) = NH4(+) + 2 CO2</text>
            <dbReference type="Rhea" id="RHEA:11120"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29195"/>
            <dbReference type="EC" id="4.2.1.104"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cyanase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.104" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5M1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008824">
        <property type="term" value="F:cyanate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1160.10">
        <property type="entry name" value="Cyanate lyase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="entry name" value="lambda repressor-like DNA-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00535">
        <property type="entry name" value="Cyanate_hydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008076">
        <property type="entry name" value="Cyanase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003712">
        <property type="entry name" value="Cyanate_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036581">
        <property type="entry name" value="Cyanate_lyase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00673">
        <property type="entry name" value="cynS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34186">
        <property type="entry name" value="CYANATE HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34186:SF2">
        <property type="entry name" value="CYANATE HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02560">
        <property type="entry name" value="Cyanate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01693">
        <property type="entry name" value="CYANASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01116">
        <property type="entry name" value="Cyanate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55234">
        <property type="entry name" value="Cyanase C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="lambda repressor-like DNA-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyanate lyase C-terminal" evidence="4">
        <location>
            <begin position="117"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1739085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="202" mass="22146" checksum="613DA7B1BB551901" modified="2024-05-29" version="1">MLSSACRRFISSPSAAAVIRSSRAAYAPASPPRAAYSSISATEIAERTKRMLDAKEQSGLSYDELASKLGVTNTYTAQLLMGQAKLTSETAIKLQEALPDASKQDIEDMTTAFPMRAFDEEILKEPNVYRTYEAITHYGEAIKSIINEQCGDGIMSAIDFYCDVGTTTGKHGEKRVVITFNGKFLPHIEQKMDDDSAKSPRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6F1</accession>
    <name>A0AAD8Y6F1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">23S rRNA 5-hydroxycytidine C2501 synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_010003</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6F1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020988">
        <property type="entry name" value="Pept_U32_collagenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001539">
        <property type="entry name" value="Peptidase_U32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051454">
        <property type="entry name" value="RNA/ubiquinone_mod_enzymes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30217:SF10">
        <property type="entry name" value="23S RRNA 5-HYDROXYCYTIDINE C2501 SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30217">
        <property type="entry name" value="PEPTIDASE U32 FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12392">
        <property type="entry name" value="DUF3656"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01136">
        <property type="entry name" value="Peptidase_U32"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042161978" evidence="2">
        <location>
            <begin position="26"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase U32 collagenase" evidence="3">
        <location>
            <begin position="604"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1739460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1099" mass="120466" checksum="2D3AA29A36DAC7EE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y719</accession>
    <name>A0AAD8Y719_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">MBD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_008908</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y719"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15489">
        <property type="entry name" value="PHD_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.890.10">
        <property type="entry name" value="Methyl-cpg-binding Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000637">
        <property type="entry name" value="HMGI/Y_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001739">
        <property type="entry name" value="Methyl_CpG_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00354">
        <property type="entry name" value="HMGI_Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50982">
        <property type="entry name" value="MBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MBD" evidence="9">
        <location>
            <begin position="762"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="8">
        <location>
            <begin position="876"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="722"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="812"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="63"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="80"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="161"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="817"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="830"/>
            <end position="846"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1740813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1038" mass="116308" checksum="0BC842DA9F711334" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8R3</accession>
    <name>A0AAD8Y8R3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8R3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035770">
        <property type="term" value="C:ribonucleoprotein granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000963">
        <property type="term" value="P:mitochondrial RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044528">
        <property type="term" value="P:regulation of mitochondrial mRNA stability"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050870">
        <property type="entry name" value="FAST_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21228">
        <property type="entry name" value="FAST LEU-RICH DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21228:SF40">
        <property type="entry name" value="LD45607P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1088" mass="122099" checksum="791EC682C7DE77F3" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8Z3</accession>
    <name>A0AAD8Y8Z3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribosome-binding factor A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007436</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8Z3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043024">
        <property type="term" value="F:ribosomal small subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000238">
        <property type="entry name" value="RbfA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023799">
        <property type="entry name" value="RbfA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33515">
        <property type="entry name" value="RIBOSOME-BINDING FACTOR A, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33515:SF1">
        <property type="entry name" value="RIBOSOME-BINDING FACTOR A, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02033">
        <property type="entry name" value="RBFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89919">
        <property type="entry name" value="Ribosome-binding factor A, RbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042121528" evidence="1">
        <location>
            <begin position="25"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="250" mass="28381" checksum="253622D720F7348E" modified="2024-05-29" version="1">MMMMMKYNCIGAALMLCCLAAAAPKMVASFATSNYSIKFRIPQSANTLQSQERNFNSQRTSSTALQMAYGKYGNGRSSSRYAAGDRTKRQERVGHVVRTELASILHKGFIRFDNDPIEDELRRRINIVHCDVSPDLRQARVTVSVMSGKDRKMDAIAKRRAYSWLVRSTKAIRHSLAQKMKHMKGSPDLTFVQVDVGAAVDVMQLIEKVSTGYKRDDVLEMEFEDDDEDGWEDEEDWIDFDDEDGVTVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9B7</accession>
    <name>A0AAD8Y9B7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TauD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_007902</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9B7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050411">
        <property type="entry name" value="AlphaKG_dependent_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696">
        <property type="entry name" value="GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696:SF21">
        <property type="entry name" value="TAUD_TFDA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042227802" evidence="2">
        <location>
            <begin position="20"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="TauD/TfdA-like" evidence="3">
        <location>
            <begin position="116"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1741424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="454" mass="50601" checksum="2050BE354626B130" modified="2024-05-29" version="1">MKIAAAALFAALAANQSTAFAPTRSSNVISTKLSSTMQPPERTAPDAGYVPDWEGRTGLAPEEFIASDMAKPDLSGMWECPLTRWDSENIDIAEAQKICSEQPHCPLEMTASAEDNAKGAAFFSENKEQIRADLLKYGAIWFRGFDLMKSVAGNREMHEALGLDPCLDPLHSSGLRKFASERDALYEEVNKPSLRQHYIGLHNESTAKRTAAYAAFVCFQRATEGGGRFLVADGAAILAELKPETLEKLYNRKIRISVSNLDIPPALPGVVKEGIKGLVDVAVAPKFDMDLEMIYESDGKPGRLQAVETAESPINRHPVTGLPVWFSNTHNHARKLRDRRPCGVPEVGMTEVFYADTMVPLDLEDCEEIKRASEKHITALSMEPGDVLLVDNYRALHGRDVFQGDRFHAVTWFTWDQNEAWRGDERRIVEKNAFNQAINQMMDWLPKDFESNQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAF4</accession>
    <name>A0AAD8YAF4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNI-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006418</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAF4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051279">
        <property type="entry name" value="PP1-Reg/Actin-Interact_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24112">
        <property type="entry name" value="LEUCINE-RICH REPEAT, ISOFORM F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="409"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="481" mass="53980" checksum="679575D40BFA8E37" modified="2024-05-29" version="1">MPFVTKNPAHYLKALAEDSAEALHIGLFFSRSISEQQAVDLIKLAKAIQQSTRTIRCLWLRFRDGDESICAALQAFGDELAGDVSIQSLVVEGKAGPAEIECLAGFFRNSKLRGLQFRRTDIDASASAILRPLFVGSDTLNVLDLSQNSKLGDVFVEDMLTALSEGETSIETLSIGECDIDAADDNDETIERISATSVELMARYVSRSKSLSSVTLRLLNLDDIGIGELANVLKRQDCSVRRLDLGGNFGNNGIKILAEALKTNQSIKTITLGCHKNLNDVGAQELLRVSDPFAYTTHANKKTEWDSVKKSNHSLQSVYILDRPSVTVSNELITKLRSISSLQPHQTLQTKAWHHIEKHIEDLSHMEIDNKYVPEVMSFVQKRGELNGLFETIRSSNSLKIFENPSPERARLSDQMDRIQKENAILKRLLKAERERSQSLRNENYSVRKTVEMKFGKKCPSWNSCKQLWLEVVDLMKEPIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAR1</accession>
    <name>A0AAD8YAR1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">tRNA A37 methylthiotransferase MiaB</fullName>
            <ecNumber evidence="15">2.8.4.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_006571</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methylthiotransferase family. MiaB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.4.3" evidence="15"/>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAR1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035597">
        <property type="term" value="F:tRNA-2-methylthio-N(6)-dimethylallyladenosine(37) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.30.20:FF:000001">
        <property type="entry name" value="tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="entry name" value="Methylthiotransferase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="entry name" value="tm_1862 like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01864">
        <property type="entry name" value="tRNA_metthiotr_MiaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006463">
        <property type="entry name" value="MiaB_methiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01574">
        <property type="entry name" value="miaB-methiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00089">
        <property type="entry name" value="MiaB/RimO family radical SAM methylthiotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43020">
        <property type="entry name" value="CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43020:SF2">
        <property type="entry name" value="MITOCHONDRIAL TRNA METHYLTHIOTRANSFERASE CDK5RAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01938">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01082">
        <property type="entry name" value="B12-binding_domain_containing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01061">
        <property type="entry name" value="methylthiotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0697">Rotamase</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="15" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042112419" evidence="10">
        <location>
            <begin position="27"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="domain" description="PpiC" evidence="11">
        <location>
            <begin position="102"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="MTTase N-terminal" evidence="13">
        <location>
            <begin position="297"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="14">
        <location>
            <begin position="467"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="12">
        <location>
            <begin position="700"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1742974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="768" mass="85574" checksum="D29880248FA971F7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBB7</accession>
    <name>A0AAD8YBB7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RxLR effector protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006994</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBB7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042089144" description="RxLR effector protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="90" mass="9819" checksum="9640A953349EAA36" modified="2024-05-29" version="1">MRIISLTLALALLVPSVHARVGTGTVPQSHHDHSLLRRRLDGAELPLADKSIVNGANIDVVQLPKWNDVETPFMSMASPSDTSKTHKDEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBN1</accession>
    <name>A0AAD8YBN1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PTEN phosphatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_006901</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBN1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016314">
        <property type="term" value="F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051281">
        <property type="entry name" value="Dual-spec_lipid-protein_phosph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014020">
        <property type="entry name" value="Tensin_C2-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029023">
        <property type="entry name" value="Tensin_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12305">
        <property type="entry name" value="PHOSPHATASE WITH HOMOLOGY TO TENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12305:SF94">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-3,4,5-TRISPHOSPHATE 3-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10409">
        <property type="entry name" value="PTEN_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01326">
        <property type="entry name" value="PTEN_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51182">
        <property type="entry name" value="C2_TENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51181">
        <property type="entry name" value="PPASE_TENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphatase tensin-type" evidence="3">
        <location>
            <begin position="171"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="C2 tensin-type" evidence="4">
        <location>
            <begin position="351"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="17"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="371"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="527"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="607"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="32"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="534"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="607"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="640"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="656"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="687"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="703"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="725"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="752"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="773"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="806"/>
            <end position="828"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1742336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="880" mass="94813" checksum="D63DA2E110BD20F4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBR1</accession>
    <name>A0AAD8YBR1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_006227</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBR1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1742630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="52" mass="6211" checksum="165460881D592F63" modified="2024-05-29" version="1">MCKGKLNFSSKDFYLYFYHAVVRSKMTSPFWILIDDDVQEVWRSLKNYAPAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCM0</accession>
    <name>A0AAD8YCM0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006599</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1743002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCM0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="487" mass="54552" checksum="7DAE03D5EA381E9A" modified="2024-05-29" version="1">MVVIRLTADQSSNLTFPIGCPVWYNFPGKKDDMGSLKRGVVKSVSLRDSQLYYEVTYCDGDENITITEEVNETNLGFGALCPVTIISDNKSGTTDDTSEGEIVMCTTDANNKVVYTAMIFMDGSQVKYESDIDAARVKYRKVKVNDMESNEEHAGNTNAISTSTKQTTDCKEDKVDKMNATQHPQQPPTQRYVPSSITCSDSVSKRSFADSNDGGGDSSRKRARYPTGAKLEVDGGYDAPAIASNSQDATNVKLLSNPKFPNVSRLEITPPLWLQKDRPSQRSLFFHLIGKHRERSENIIKRINQESQCRVHVDMKNDVFVPIKINVEPLNVSTAQQDLFRARQMLQDLFLDYVGNDGCRGRLVCEIAQACWGAHRPSLSTSNAVKDINPLLDNRMVRYMSIVELSFDEHTREFHAAHILHKPFLREITGLGCDLILVAKGFRVSTNACDPYVFVYGRQYQDVDKAVQLVKKKIRQHQHVCGKCVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCM2</accession>
    <name>A0AAD8YCM2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_005740</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCM2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046523">
        <property type="term" value="F:S-methyl-5-thioribose-1-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="entry name" value="Translation initiation factor eif-2b, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43475">
        <property type="entry name" value="METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43475:SF3">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G14290)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="8"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1743119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="431" mass="47548" checksum="7DFC353552C0C440" modified="2024-05-29" version="1">MRTATLSNIKRVVSVFILRQNNNDEAQVALFRRCSQMPTFGGHWAAVSGSIETQDVSPLATADREVGEETNLGELLGDYDHLLNSGLHIDIAIDKSKGTFGGRMIRVYPFALTLPSEDIQLLSNIEMRGTEHDKMKFLRISDFLGMSDQCVPSLKRAFHHATSGRYLDLPQEIREWEGDRVNGAAYLARKAVDLAAAHTQSGELSEDELSTAQSIAILRPSMVPIVNAMNEFDRRIKHEGYGQIEQVKDELLKSLTDEGNRCVELGYELVMNMYKSKAPSTEFVIGTFSRSSTLKSILQRIIESSDDVSAKVRVACSQSTPGDEGILMATDITGASCLPDEEFQQQVIDGKMDVVIVGADCVLSEGNGVVNKVGSEALASVCKQAGVPIISSADRWKLWSDIHCPPLEDIFELIPSELFNHVLVPKDEEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCW5</accession>
    <name>A0AAD8YCW5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCW5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="364" mass="38983" checksum="DBFC555B2F5AF9C1" modified="2024-05-29" version="1">MYAPSYHKSMLIKQDLHQSASNTNQSLQLQLHRPTPSYQHEVHYNHDCCPPCLGISSPASAAEPLLRGAHATFEKQAAEASSILTTCEDPNCGGTAKEGEQCSKFIGFGVYCETGLYCIEANTCNLTYESGGAFCCPNGSQPNNQRQCIPNSACTFGPPSPSPPTPSPPSPPASPRPSWAPAPAGSWSHGCPDGPWGGISHDGGDAYDFSKTPATGSWACRPGNNPPQQILQSNLDKFKNGGEFQSIMIGGTMTTVRKTFGHSLDTAKQGCGECWIIKPVAPDGKCGTFGTCNLKDPENPPVFLLMSVSEQKKDTLHKPEISNSAFTDGLDAFKENDGCNDLIDGKWSFEYQPYENADLGCIAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD94</accession>
    <name>A0AAD8YD94_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004884</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD94"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="278" mass="30549" checksum="22CFA2EF3EEF86EE" modified="2024-05-29" version="1">MPNKQDTDLLEYLRTHKSSHVRLAVQKIHASFEASSAFMKSATSRPSGVPAAPATPVRRTTISSTPTTNSAVKRHIEHLERKIIEQSETTTRNESLLSLSPRSHQRITVSPRYAFSPKQLYHKAGWDNDDDTTVSTVSISSMSMSSSLSGDRPIMEIRFERSCLGERPSTNMFGSSPSSDAICKIEHISILDAAFDGAVSYAHTLSTSRGCPSETATSSNEAEEGPEKGVFHYYFVLSVLLLSAKGVDPFVVCTIYLWLEIFRQHTSGCKEQSSKGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDP9</accession>
    <name>A0AAD8YDP9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDP9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041904502" evidence="1">
        <location>
            <begin position="19"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="103" mass="11837" checksum="92AA71B684F78CE9" modified="2024-05-29" version="1">MISYKWFITLLTLSLGRADHDVNEKYRLFDIRHDKQRIDGWQDSVAVNVDANVDVNEMSIPMFQSIVTKEKGGASMTLKVVNQKVANATKQKWKVQVRKEQVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEK3</accession>
    <name>A0AAD8YEK3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">tRNA (guanine(37)-N1)-methyltransferase</fullName>
            <ecNumber evidence="10">2.1.1.228</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">M1G-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">tRNA [GM37] methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">tRNA methyltransferase 5 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_004043</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>guanosine(37) in tRNA + S-adenosyl-L-methionine = N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36899"/>
            <dbReference type="Rhea" id="RHEA-COMP:10145"/>
            <dbReference type="Rhea" id="RHEA-COMP:10147"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.228"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion matrix</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="10">Predominantly in the mitochondria and in the nucleus.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the TRM5 / TYW2 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.228" evidence="10"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEK3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052906">
        <property type="term" value="F:tRNA (guanine(37)-N1)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070901">
        <property type="term" value="P:mitochondrial tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002939">
        <property type="term" value="P:tRNA N1-guanine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.110:FF:000001">
        <property type="entry name" value="tRNA (guanine(37)-N1)-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.110">
        <property type="entry name" value="Met-10+ protein-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03152">
        <property type="entry name" value="TRM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030382">
        <property type="entry name" value="MeTrfase_TRM5/TYW2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056743">
        <property type="entry name" value="TRM5-TYW2-like_MTfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056744">
        <property type="entry name" value="TRM5/TYW2-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025792">
        <property type="entry name" value="tRNA_Gua_MeTrfase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245:SF36">
        <property type="entry name" value="TRNA (GUANINE(37)-N1)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245">
        <property type="entry name" value="TRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02475">
        <property type="entry name" value="TRM5-TYW2_MTfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25133">
        <property type="entry name" value="TYW2_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51684">
        <property type="entry name" value="SAM_MT_TRM5_TYW2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 10 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 10 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SAM-dependent methyltransferase TRM5/TYW2-type" evidence="12">
        <location>
            <begin position="73"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="222"/>
            <end position="223"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="251"/>
            <end position="252"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1744752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="348" mass="39128" checksum="06D48B0B7653EE35" modified="2024-05-29" version="1">MIESSAEEDSSGSTSPNGKPEIRPSYIRLSASPYSLLSVDQVLRRIMPCQNDDSGDAINDNGNPLIEEIPSSFEVAGHVAHVNLREESLPYKYLIGKAILEKNKPKIRVVVNKIGNIENEFRTFPMEILRAKDWILIYGTEEHGCRFKLDFAKVYWNSRLSGEHEYLVKQIVSSAHEELLVTKERHCIVADVMGGVGPFAVPLTSANASHYHTTPILCHANDLNPISYHYLQANAKLNRCFSDRLVKYNLDGRAFIHKMNEEGVDASHFIMNLPASAPEFLDAFKGWNFESTSSKKIPTIHVHCFGEKARGPEEKSRIHTQVLQRCERALGCPGSLSEPEGRQKTRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEW9</accession>
    <name>A0AAD8YEW9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YqgE/AlgH family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEW9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1740.10">
        <property type="entry name" value="VC0467-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003774">
        <property type="entry name" value="AlgH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021067">
        <property type="entry name" value="Glycosyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34496">
        <property type="entry name" value="GLCNAC TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34496:SF6">
        <property type="entry name" value="GLYCOSYLTRANSFERASE 2-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02622">
        <property type="entry name" value="DUF179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11397">
        <property type="entry name" value="GlcNAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143456">
        <property type="entry name" value="VC0467-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="376"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="629" mass="69390" checksum="1971C1584D7BFF16" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFQ9</accession>
    <name>A0AAD8YFQ9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_003402</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFQ9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.110.10:FF:000002">
        <property type="entry name" value="Phosphatidylinositol 4-phosphate 5-kinase 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215:SF14">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="67"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="165"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="488"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="541"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="812"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="122"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="205"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="497"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="541"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="573"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="597"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="630"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="657"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="705"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="824"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="835"/>
            <end position="844"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1745478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="988" mass="110857" checksum="62ABF7E3EA2BAC25" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHD9</accession>
    <name>A0AAD8YHD9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dynamin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003389</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHD9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042163235" evidence="2">
        <location>
            <begin position="39"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="469"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="543"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="555"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="666" mass="75204" checksum="433362DE08C37F91" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YI09</accession>
    <name>A0AAD8YI09_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nucleotide-diphospho-sugar transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_003369</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YI09"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1745445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="599" mass="67507" checksum="114FE83A10AC837C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIH4</accession>
    <name>A0AAD8YIH4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIH4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="147" mass="15937" checksum="CAE1EDE7148AF4CB" modified="2024-05-29" version="1">MSANEWSVGNSWGNSWGGRRQLNKNELPSAFSMWPFDRDANEGHEVAIKGREWGSDDWSWGATDDWHNWGGSSGKSGKSGASNAWSSGKSGKSGAWGSDDWSWGATDDWHNWSGSSGKSGKSGAGMLGAVVRVARVAPGMLEQWQEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YII7</accession>
    <name>A0AAD8YII7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YII7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="172"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="269"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="322"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1155" mass="128613" checksum="D325412888299FA8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIL0</accession>
    <name>A0AAD8YIL0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003785</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIL0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="316" mass="36045" checksum="FA6BB7CD6CD213DE" modified="2024-05-29" version="1">MYYSRGGKRPVLPRSIPKRSDTLLHPTIYLFSERQSASGSNYDLFHKLRARSPRVVRSLFIKGSCAFIACLATITMVSLRIGRMRAPSSVFKRKSSKKSLRGKENDPTSKRNIEDSISHSSDQSTTDESMGSSDGNNIDKPIVVHLFGSTDSGGNKFTYKPANRRPSLRKSSSNGSFKISDSVREAIQKRTSSVYRRRSSIRGQGVTFLDEVLGLTPRHIVTQTYYRPRTSIEERKTMYYSSKDILLFERELLCEKVEAEIKAIERQKKKEQDGDVSIEDEDSDNEPLDLEQVQKLVQKVRNRLNLEQYTKEDAML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIL2</accession>
    <name>A0AAD8YIL2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002106</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIL2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042040944" evidence="2">
        <location>
            <begin position="21"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="189"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="215"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="238"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="268"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="300" mass="31581" checksum="F76B2D0B276437F1" modified="2024-05-29" version="1">MKLISATSILLISSSGVARALLPPGYEDNMHCPPGSCSLFINGIVGPKHSIYKCYDETTDQTTDAVWTGFRTQVEAPEGWIEDPEECDVAPTPAPSTPTHKNIDKPGGLCTTDSDCRIKIRSAEPLGAVGPRLCGCYAASRRLPFDETEGQTSFRRARCLPSACDRFEAYCPLASNDNGMAECALRPIDTSSTSTSSSSDDSPRSRPKPKKHNRSTTSSSTSTSSDAPPSISKKRTGSTTTSSSTSTSSDESPPSNPIKKRKPAQVQSTTSAAASSDDSSTGIVSPTPAPAPPVQAVAEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIU1</accession>
    <name>A0AAD8YIU1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002427</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIU1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042184310" description="Secreted protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="137" mass="15400" checksum="FB7F42A8C1C95B3F" modified="2024-05-29" version="1" fragment="single">MFQHQRALCCLLCALMGITTHRTFAFTSSFEPRNNMHITKSNHPTKLHMSPSLLTPLLPKKQRQLCKEMPMEMPSLLLLLLPEGLRGEVITVHDTNAADRPQPVLVKFGADDEERSDGYSLPSAFSMHLSANEIMVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKN5</accession>
    <name>A0AAD8YKN5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FAM207/SLX9 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_001850</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLX9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKN5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028160">
        <property type="entry name" value="Slx9-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31109">
        <property type="entry name" value="PROTEIN FAM207A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31109:SF2">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN SLX9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15341">
        <property type="entry name" value="SLX9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="154"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="38"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="100"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1747887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="224" mass="24897" checksum="6018C51B5DDA35A3" modified="2024-05-29" version="1">MGKASRAGRSKTPAKAVSSRLVKHAPLTTTGAKILVSPKSQTAGENESLSRGQRKRLAKREQFLKRERMVMSSLRLKKLEEQKGKLDGLDAIKEALTSTTSTATEAQSSAHPSAPAVQQLSSQTVKAKKNLANSEIGHMGLVLEHPSFIENPFAAIQQHLRNSLESDAEMLQEESLKREKEDKIIEDKKKEEKKEKIRDIRFARRMGRLASKLLEGVVYSIVNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YL37</accession>
    <name>A0AAD8YL37_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YL37"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050276">
        <property type="entry name" value="MshD_Acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43617">
        <property type="entry name" value="L-AMINO ACID N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042057530" description="N-acetyltransferase domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="66"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="249" mass="27328" checksum="3B2A537631DBA771" modified="2024-05-29" version="1">MRTILLAYLAICITTTAAFAPPAFGLGALFRPPNIKIIKSDGIRLEEAGKFFVDAFWTGKVGGGADTLSPKQAFQLERQQVAEFNKRYRRRAAKQSGRLPGNYAGQSLDSSSELVLCVNGSDEVIGCAGVEVSRIKKMDGYDSSFSGPLMSNLAISRKYRRKGLAEDLVKAAENIARREWGYDDCYLYVEKRNTPAIKLYQKLGYKSIWEDDSATTLLPTGDGRIANGKTTIVCMKKRIGAGLFGNLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLA5</accession>
    <name>A0AAD8YLA5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Iron-binding zinc finger CDGSH type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_000051</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLA5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010506">
        <property type="term" value="P:regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.90">
        <property type="entry name" value="CDGSH iron-sulfur domain, mitoNEET-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045131">
        <property type="entry name" value="CISD1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018967">
        <property type="entry name" value="FeS-contain_CDGSH-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042216">
        <property type="entry name" value="MitoNEET_CISD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13680">
        <property type="entry name" value="CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13680:SF5">
        <property type="entry name" value="CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09360">
        <property type="entry name" value="zf-CDGSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00704">
        <property type="entry name" value="ZnF_CDGSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042009374" description="Iron-binding zinc finger CDGSH type domain-containing protein" evidence="8">
        <location>
            <begin position="27"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="Iron-binding zinc finger CDGSH type" evidence="9">
        <location>
            <begin position="59"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="110"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1748112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="313" mass="33967" checksum="35958D93224E58E1" modified="2024-05-29" version="1">MISSSSPSLLSGAALLLLLSASTTHAFTPPSTHHATTTTSSSKTQLHLSKRINNKISLDSPKVATMENYGSTDNTKTVYCRCWKSETFPMCDGSHMAHNKECGDNLGPLIVSVDTKKKEEEAVVEEEEEEEEEVVEEEKAVVVVSSDSLATPEKTTSSPFSKLKSIFKKDNKEGPTTKEKLAKMGLSALLSYGWVSNMSYAITLSLSWYTHSKKTGLSPLSPGQWKPFLAVYAGFYVFTNIIRPLRFGLSVVVSQYFDRFVGFIERKSGWGRKASIGVVVFLANVCGTFAAMGLGVGVASTLAGVPIFPPKVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLW7</accession>
    <name>A0AAD8YLW7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000973</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLW7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="112"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1749034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="263" mass="29222" checksum="004940336C8DB0B1" modified="2024-05-29" version="1">MRDSLFLSAAFIIVEIGLIVATSIAAYELWIGDFIWANEEKQRPTIQSQRGGGISYEPLYNTTRREYYDRSLSATQKDNRSGSSRRTSSPDDGYDRTTNPGRGSTGDSTRRLFYKLILIALLCRLICFPIETFTVSTVITAELTSTNKHEPMDPPSWVLLRASQTLPDMAFASAFGLLIVFCAQVAYAALPLTSQSSDGSLGADDNAVGNGNTSPQPARDDDFNKQQSVTNRFSYKVFLTFAQVVQGRRLRQRLLSSCGTQYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLY5</accession>
    <name>A0AAD8YLY5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLY5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="684"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="518"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="537"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="559"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="616"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="717"/>
            <end position="726"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="726" mass="78569" checksum="CE2ADAB0AF64F44D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YM09</accession>
    <name>A0AAD8YM09_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ZPR1-type zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_001015</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ZPR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YM09"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.1040:FF:000006">
        <property type="entry name" value="Zinc finger protein zpr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1040">
        <property type="entry name" value="ZPR1, A/B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004457">
        <property type="entry name" value="Znf_ZPR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040141">
        <property type="entry name" value="ZPR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042451">
        <property type="entry name" value="ZPR1_A/B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056180">
        <property type="entry name" value="ZPR1_jr_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00310">
        <property type="entry name" value="ZPR1_znf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10876">
        <property type="entry name" value="ZINC FINGER PROTEIN ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10876:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22794">
        <property type="entry name" value="jr-ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03367">
        <property type="entry name" value="Zn_ribbon_ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00709">
        <property type="entry name" value="Zpr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger ZPR1-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1749076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="169" mass="18618" checksum="ADDC28DAF43DBA5C" modified="2024-05-29" version="1">MSLTCEKCGYKSNEVKGGGEIASHGTRITLRAETTCDMSRGVVKSDTACVAIPEIDFELKESGLGLYTTVEGLLMKMHDGLKQASPFASKDSTTHDKFDKFLSELKNMAEGNRLPFTLIITDPISNSFVGPITESGQAFVQQADQSISDDKRISIEEFQRSREEDDRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YN02</accession>
    <name>A0AAD8YN02_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YN02"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="400"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="440" mass="47260" checksum="5022129EBC90FC7D" modified="2024-05-29" version="1">MNPNFGYGGYQLPPGFSGYAQSQAAAGNAQGNPLPPQGAGATNNAGAAPPAASSMMPPMGVMPNMMMTDAAAAAYMAGVPSAAVAAPATEKKSKVHYCTIHPEGMPRSFDVPFVERRLPVCDRCKKNFKSRDLCRKRDGHKALPWQMTYVVVTMDSSVLHEDENGNVTLQSIPMVCELQDTPHMCLGPADGSMKSEPICKVCREKNYTRDYCRNTCKHTTPPWSTTYVKLVADTKPKDDDRFMQYSAKKRKARQEDGVNGKPKPQEEGENVYENSDDLSIVHKSRTFLCSVSSTKLVARWCERIQYPAKPNSNATAANSDIEPGNDGAPAPPFSPYGAPSTSEQANNAQLWDAFRAGAMWAQSQGAQASLPSVMPPGYPFGNPTGAPPLFNGNDQVSWNAYGQGGQLADLGEPSMKKSKTDNGDGSSSNGTEGVSNNVQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YND4</accession>
    <name>A0AAD8YND4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">60S ribosomal protein L24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_000215</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YND4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.20">
        <property type="entry name" value="Ribosomal protein L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038630">
        <property type="entry name" value="L24e/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056366">
        <property type="entry name" value="Ribosomal_eL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000988">
        <property type="entry name" value="Ribosomal_eL24-rel_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792:SF1">
        <property type="entry name" value="RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01246">
        <property type="entry name" value="Ribosomal_L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL24-related N-terminal" evidence="5">
        <location>
            <begin position="2"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="87"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="106"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1748276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="134" mass="15333" checksum="4CC1297DF4E3517F" modified="2024-05-29" version="1">MSEYRIWPGTGKLFIRRDGKPIYLGSSKAQSLTLQRKKPAKLVWTQAWRRLHKKGITETNLKKRRTRSTKVQRAVIGLSLDDIKKKAAQKPEFRSAQRDAALKEVKQRKKDNKAKGKGTSSGVRAPKIPKNVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YP69</accession>
    <name>A0AAD8YP69_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="8">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_000791</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YP69"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF6">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE IA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="47"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1748852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="218" mass="25145" checksum="5D58891238EB6D8F" modified="2024-05-29" version="1">MYRKMWDKAMNGVHEQLLQKSTPNGLTYIADRLNGGRLDHKMDHLACFMGGSLALGAYTDPSGIDSSRAKRDLKTAKALTYTCYQMYARTQTGISPEFVQFRGGNDFKVPSSAPFYILRPEVVEAFYYLSVLTGDPIYREWGWEVFQSIEKYCKTEYGYGSLHDVNEPSMKPEDRMESFFLAETLKYLYLLFDPDSEIDILNKHVFNTEAHPFKIFNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D433</accession>
    <name>A0AAD9D433_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016173</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000053">
        <property type="protein sequence ID" value="KAK1733196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D433"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="139"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="62"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="95"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="330" mass="37443" checksum="1408A91EB411AE22" modified="2024-05-29" version="1">MIATLSTIIPCSSSKSKLGSMWRIPLHSHTQYSSSSFSHGLICRRQSFLTVTAQLFSNGSNNNGGVGDAGKGQGNDDSEECPGISHGLVGICINNSSNPSGSGRSNAPSKSSKKPKSLWEQVRLLEEKAPQKVASLKKFRRLEQEKNILLKEKKALEKELNNRPDGLFNEAAVSLKKFRRLEQEKNIIVKEKKALEKKLNNRPDVPILFHGHYKFGPENIQDLSRLISMHLMNKPSEIDSNRIYSCVSKLMSRYLAYKPRGIDSNRIYIFLRGIPLVRACFTDLEYDYHDEPEYYDTDNMRMLLATCLASNWFKGDQLKNIKQWNNDHFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4K4</accession>
    <name>A0AAD9D4K4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016619</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000060">
        <property type="protein sequence ID" value="KAK1732720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4K4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="270"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="404"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="499" mass="57309" checksum="AF847900EA3F0B5A" modified="2024-05-29" version="1">MSYITPLKGRRSEGGSSYPSGERYEPGMLSAIKSEDDFATFLGVQKKCIEIIEPMNDQPCKTKLCPFVAIKGNNKHCPIHRRTWFPLPGTRGDNMHGPSFFRHANVGGRICDCDQASCRQAGYFPNQSALAIPKQARDVILGTGMLFLEEKLHDFVDNPEKRIYLYPWHFFRRHLTFKNRKWSFKYNDDNIYADEEGKKFPCPPPNNSVRRFVAEELLSTTSPKDRWTTTGMPKWLMVMLAIDDNESDSALSKKVEAEEDMSPKAMQMKVELHRARAHSLKEQLDEKVKNSDAILAAVNERHAKEKLAWKEKHDAALSELKQKHEKELKANEEQLKANEQTYKETLKANEQTYKETLKANEQTYKETLKANEQTYKETLKANEQTYKEALKAKDADISAATSVIHDQKETIERLNEMIANLDEDVKEKAELLKQLRASGGRPLKFQDLFDGGMLSKNVKNFTFFHTAKQNDLFLEVLSMVFSTHSWQSRPLEPNTPACF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D699</accession>
    <name>A0AAD9D699_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">carnosine N-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_014723</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carnosine N-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.22" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000038">
        <property type="protein sequence ID" value="KAK1734475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D699"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030735">
        <property type="term" value="F:carnosine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012901">
        <property type="entry name" value="CARME"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12303">
        <property type="entry name" value="CARNOSINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12303:SF6">
        <property type="entry name" value="CARNOSINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07942">
        <property type="entry name" value="CARME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01296">
        <property type="entry name" value="N2227"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1734475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="456" mass="51111" checksum="F073C18761756B9C" modified="2024-05-29" version="1">MTISSLLSSYSSSVPLRPSTSSCPIFATAFQIQASVSVPQQQLSTNRLQNHEADKIETLVKEKLNRIATGYQIHGEKMKRTLEMELELSGKVEKCFMGDNADGHNQSLLLSTKLKEKKVRLEECLAVNDRVVHQLLATNSKGGQSSLFRDVQFIPSAAAGSTGEYDDLGQLMGNGGLVEGGETKKETDGYDTALQVIHHTARDWTGVVPHVEANDSSVTMIFAAQNVIKMLQQQQYQHQQEGNRQLQSAIYPFLSDLQVNEIDARKRFEMEVFPDEHAVDSYKCYHDLTGTHPNLSFTVGDFVSTYSQQSKQNQYDVVATSFFIDTATNIYEYIYIMKHMLGTNGIWVNCGPVQWHPCALLRPTVEQLKDMLQVAGFELISWSVADEAVAYRHPDDVGGKGLEARYTRSEAYRPLRFVVRLLSSQDDGRSSNDDLPFKIQYSEFLNEVANGKIEVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7L4</accession>
    <name>A0AAD9D7L4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">WRKY19-like zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013424</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7L4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056866">
        <property type="entry name" value="Znf_WRKY19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24906">
        <property type="entry name" value="Zf_WRKY19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="1">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="131" mass="14356" checksum="73C89E4C477CF903" modified="2024-05-29" version="1">MVRRSNDAAVKDAQIMLIQEEHGAKRKRCNSDGCTNNVVNGGVCKRHGAKVEYKRCNSEGCTNVSVKGGVCVKHGANLKRCRSKGCTNYAQKGGVCIKHGQRLRSKNVAAKDAQIKPSVEECVKGMQRRMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8L5</accession>
    <name>A0AAD9D8L5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldolase/RraA family protein</fullName>
            <ecNumber evidence="2">4.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8L5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16841">
        <property type="entry name" value="RraA_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.40">
        <property type="entry name" value="Ribonuclease E inhibitor RraA/RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005493">
        <property type="entry name" value="RraA/RraA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036704">
        <property type="entry name" value="RraA/RraA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33254">
        <property type="entry name" value="4-HYDROXY-4-METHYL-2-OXOGLUTARATE ALDOLASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33254:SF4">
        <property type="entry name" value="4-HYDROXY-4-METHYL-2-OXOGLUTARATE ALDOLASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03737">
        <property type="entry name" value="RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89562">
        <property type="entry name" value="RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR605493-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="303" mass="32134" checksum="574D4A882F726245" modified="2024-05-29" version="1">MLTITRLGIPAALRHQSRSASVHLAALGRGAGKAKKPDLTEHQQNGDVKDIIKRLQKLGTGPLCDADKGHKLTSSTSDDPDLKKYKGLNLMDTDVMKLRHAPKQSGGVMIGVARTVQLPRPNDFLAVLSALTELSAGDVLVVNTGGSTRAVAGSLFTTEATRRGVNGIVVDGPIRDVAELECFAYSTKITPYAGTVQHVGEGVDVSSVQCAGVTVNPGDIIFGDSDGVLCGSVDTFSACLHDAEHIVAAEQRLIEGMKVGNSLHSMTNFDEHFAARKEGRESSLTFKDLRTVKFTGIDSVEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8Q5</accession>
    <name>A0AAD9D8Q5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoglycerate mutase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8Q5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47580">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47580:SF1">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="405"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="465"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="474"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="575" mass="64323" checksum="E7060101424EAFCC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9X2</accession>
    <name>A0AAD9D9X2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Lon protease domain-containing protein</fullName>
            <ecNumber evidence="4">3.4.21.53</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_009360</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.53" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9X2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="entry name" value="LON domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46732">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE LA (LON) DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46732:SF8">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE LA (LON) DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042121557" evidence="2">
        <location>
            <begin position="31"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="Lon N-terminal" evidence="3">
        <location>
            <begin position="164"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1739601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="528" mass="59586" checksum="F868D9CC02FCAB6D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBF2</accession>
    <name>A0AAD9DBF2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4336 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009394</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBF2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025638">
        <property type="entry name" value="DUF4336"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835:SF2">
        <property type="entry name" value="LYSINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835">
        <property type="entry name" value="YALI0C07656P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14234">
        <property type="entry name" value="DUF4336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041945897" evidence="1">
        <location>
            <begin position="17"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="495" mass="54384" checksum="35B647C6E9981400" modified="2024-05-29" version="1">MKTASSFIALSAAALGIVTEGFQSIPVASNIRTFTSSSSPLQSSTADNNNDALIKTEVSRRQTFELAFAAIGLTTTFAGTRENTPQDYGLWGILPVGPYKRKKTIMESIVDDTMWTFDQKFGILNVQVPLRMTVIKLPDGGLFVYDPIAATPELLGMMTELEKLHGPVKHIVLGSVAIEHKTYAGVFAQKFPTAQVWTQPGQYAFPSNLPIPFLGFPAGRTNVIPANAADAPADWKDFEFRTLGPLISKDGAFGETVFFHKPTKTLLVTDTVVEVTKEVPKIFEDDPKPLLYHARTTVTEVVEDTPEIRERGWRRVVLFGLFFTPGSLMIKDTNTALAERRPDINSDFAGIYPWDWVGDDIASFKALQGGLLVAPILQQLILNREPIEVLDFADEVAKWPIKRIIPAHLKNNLKYTGKDYRAAFSFLEAKGVKKGLPKPLDIDMKSLRDAEVGLLESGAVAKCPPLPGGKVSREEILKQTVYGCRADLCAPSSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBG8</accession>
    <name>A0AAD9DBG8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">U3 small nucleolar RNA-associated protein 18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_009439</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat UTP18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBG8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045161">
        <property type="entry name" value="Utp18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18359:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 18 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18359">
        <property type="entry name" value="WD-REPEAT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="479"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="75"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="263"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="141"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="187"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1739680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="660" mass="72932" checksum="40E04A6EA3A4FA2F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBG9</accession>
    <name>A0AAD9DBG9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Importin beta family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008459</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBG9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058669">
        <property type="entry name" value="TPR_IPO7/11-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997:SF7">
        <property type="entry name" value="IMPORTIN-11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997">
        <property type="entry name" value="IMPORTIN-7, 8, 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25758">
        <property type="entry name" value="TPR_IPO11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Importin-7/11-like TPR repeats" evidence="2">
        <location>
            <begin position="823"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1201" mass="131295" checksum="D473CA2B59E07FC2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBN8</accession>
    <name>A0AAD9DBN8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009649</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBN8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041914473" evidence="1">
        <location>
            <begin position="17"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="183" mass="19995" checksum="33496AF00DBBAD82" modified="2024-05-29" version="1">MLRLLYATLILSPAAGALVQVMASGDSAPIAMDEIEGAKAARLMKNKEDIDTQSTYHENDIKDTGDVTDEYAARLVRNRGPITAKLTASGSHTHHCFGSYRDDSPCHAKTSLSVWKFAGKEGSVHGVIEEKFSNGEMLKVDVDCMVRDEFNKEAIVEGLSRRAETKQGVSKLVGAFLWKTCLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBP0</accession>
    <name>A0AAD9DBP0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase family protein</fullName>
            <ecNumber evidence="1">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_007895</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBP0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034256">
        <property type="term" value="F:chlorophyll(ide) b reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015996">
        <property type="term" value="P:chlorophyll catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010304">
        <property type="term" value="P:PSII associated light-harvesting complex II catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052625">
        <property type="entry name" value="Chl_b_Red"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24314:SF21">
        <property type="entry name" value="CHLOROPHYLL(IDE) B REDUCTASE NYC1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24314">
        <property type="entry name" value="NON-SPECIFIC LIPID TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1741417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="331" mass="35393" checksum="82B1278FBBAC36A9" modified="2024-05-29" version="1">MKYFSIIVGLAAPFCNGFTAPLTPSVTSPRSSTSLNAMPDGGVVITGSAGGVGFAYAGEFMDRGYDVVICDVKDCATAAKALTARHPNGKVFHTQCDVSDAASCEKLGKFAQEKLGKIGYWVNNAGINGGRRALSELSMQQVETVVKVNLLGIFYCTKVAIDIMAEQDGFTGHIFNTVGSGVKGGGTPGYATYGATKRGLPQLTASLVKEIDEGVQGYEKKQTKGTIQVHSLSPGMVFTKLLLDDSTPELRKFPFGVLAAQPEEVAADLVPKILAQKDNGGSVEFLTTDRILTKFFERFILQKKSEYIDDDGNVIKVPGEQYDETGARALY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DC22</accession>
    <name>A0AAD9DC22_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helicase-associated domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007589</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DC22"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005114">
        <property type="entry name" value="Helicase_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33418">
        <property type="entry name" value="HELICASE-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33418:SF1">
        <property type="entry name" value="HELICASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03457">
        <property type="entry name" value="HA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase-associated" evidence="2">
        <location>
            <begin position="369"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="137"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="465" mass="51714" checksum="391B5E550363CF13" modified="2024-05-29" version="1">MSSPVLPDRCGTADTTKSDDPLDGKPSEDAKLTHVDSCSSLPEAGDDLVPCARRISSQPNHQPGRNEEFGDDTLMQLLANASSLLTQQDLALPPNDPRVFLPTPFAPGQSAATLLERELQRKKQQENEEWNALQSKTTMSSQAAVSASTQVAGSTQSQAQMRLQTSPFVMQQQLQLGRGQPRPTGISAHDPYFQQQLQPQQRFLNLQQQLSSGGGLLNPQQINPIQRQRMYAPNAPPLSFQQSNMNDMSILNDMSIPALMGVGVGVGLPQLDAFGGTASNAMMNNFIPGFMPNNVASALAFTANNGMDMNTTRLNWLLQQHPYEEDQIPALTTQIRNHKKAKAPKERAATKTAAKRTDRGNSNEPPRPNRWTQRYNELLEFKRIEGHCRVPHGYPPNKKLSWWVMNQRAQHTQRQTGKSNWLTDERIKLLEDIGFVWSPNARRSVSSLKAPAKKARKVKVMDEEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DC70</accession>
    <name>A0AAD9DC70_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008523</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DC70"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="2">
        <location>
            <begin position="86"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1154" mass="128325" checksum="7C0BB0ACFAC775E7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DD13</accession>
    <name>A0AAD9DD13_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Codanin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005747</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DD13"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040031">
        <property type="entry name" value="Codanin-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28678">
        <property type="entry name" value="CODANIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28678:SF1">
        <property type="entry name" value="CODANIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="855"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="256"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="856"/>
            <end position="869"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1246" mass="138756" checksum="AD1365D1321BCC9A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DD20</accession>
    <name>A0AAD9DD20_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008002</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DD20"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042074949" evidence="1">
        <location>
            <begin position="24"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="208" mass="22969" checksum="BD0D529E099EF7DC" modified="2024-05-29" version="1">MKAAQTLTTAAALLCALPASVVALSKVETRNLDIAEDDVSRGLMHVTVDFKDECLHKHKDVCIAAINAKLAAYPELFEDREAFEFEVNKVREATDEGYNIVSMRLNVDETTVGGLLGDGMIWYPYEWCLAADDCYTVGPWDCDVGIPLLPEQCCKMIQDSVPHEDMNGKYLECYTEYPVGSPSNPVNPGRVCIHTDADGIVVHIPKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDE7</accession>
    <name>A0AAD9DDE7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein kinase family protein</fullName>
            <ecNumber evidence="5">2.7.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_006182</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.-.-" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDE7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="7"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="365"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="811"/>
            <end position="1092"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1743561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1116" mass="130831" checksum="0C9150B00418FF72" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDY5</accession>
    <name>A0AAD9DDY5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005668</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDY5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="234" mass="26100" checksum="AFEA9AEB20CA7726" modified="2024-05-29" version="1">MTEAEKALKEKRSLPPLCETNYPLVSNWVKKMKELSTKVMQNGAFNADSSQLSSQLKSFTPTSSPTKNLNLGETTAAADLSVMVATAAGTSATKFPSPTSSRVQKGMEAIVSSKRKRTKIDPPSEEDLHRQKVAAAVMAKHGITADAATGRQKRCKVCGLIKKDFYFNKDNGRSTIEAGVPHFTTRSREKNFVFCPLADDHEIYYEHQRLCQEEKMQRNKRQYAENCKRGSKSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEH9</accession>
    <name>A0AAD9DEH9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RelA/SpoT family protein</fullName>
            <ecNumber evidence="3">2.7.6.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006427</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.5" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEH9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008728">
        <property type="term" value="F:GTP diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21262:SF31">
        <property type="entry name" value="GTP PYROPHOSPHOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21262">
        <property type="entry name" value="GUANOSINE-3',5'-BIS DIPHOSPHATE 3'-PYROPHOSPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13328">
        <property type="entry name" value="HD_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="140"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="691" mass="77820" checksum="485CD4DA78693371" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEI0</accession>
    <name>A0AAD9DEI0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycosyltransferase 61 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005825</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEI0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049625">
        <property type="entry name" value="Glyco_transf_61_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 61 catalytic" evidence="2">
        <location>
            <begin position="409"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="634" mass="71786" checksum="DCDB6DE90B3389DA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEL5</accession>
    <name>A0AAD9DEL5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_006440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEL5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1742843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="68" mass="7738" checksum="4795EE638216D13A" modified="2024-05-29" version="1">MCRLIDHLEAWARAINAGTEWATSQVFDALKPRDDKLCFDDFADWYQGRMSKYTLVGIARFAQVGAPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEP2</accession>
    <name>A0AAD9DEP2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004172</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEP2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="88" mass="10374" checksum="F4703531E2AADB11" modified="2024-05-29" version="1">MSFIEKAINPAFYKQKISTWSHATAEYYKPLFRSGSVKPLWHIMIATSVLMYTQNYLFNKGTHIQHARQEKKVALEEYYKNHNITPGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFI3</accession>
    <name>A0AAD9DFI3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Biphenyl hydrolase-like protein</fullName>
            <ecNumber evidence="4">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_003735</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFI3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017171">
        <property type="term" value="F:serine hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012967">
        <property type="entry name" value="COMT_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46331">
        <property type="entry name" value="VALACYCLOVIR HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46331:SF2">
        <property type="entry name" value="VALACYCLOVIR HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08100">
        <property type="entry name" value="Dimerisation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="47"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="O-methyltransferase dimerisation" evidence="3">
        <location>
            <begin position="305"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="2">
        <location>
            <begin position="451"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1745811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="628" mass="69406" checksum="5DCA3C618A6B8175" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFX2</accession>
    <name>A0AAD9DFX2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">inositol-3-phosphate synthase</fullName>
            <ecNumber evidence="6">5.5.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">QTG54_004908</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:10716"/>
            <dbReference type="ChEBI" id="CHEBI:58401"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="5.5.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Polyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the myo-inositol 1-phosphate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.5.1.4" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFX2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004512">
        <property type="term" value="F:inositol-3-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006021">
        <property type="term" value="P:inositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000107">
        <property type="entry name" value="inositol-3-phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000055">
        <property type="entry name" value="Putative myo-inositol-1-phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002587">
        <property type="entry name" value="Myo-inos-1-P_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013021">
        <property type="entry name" value="Myo-inos-1-P_Synthase_GAPDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11510">
        <property type="entry name" value="MYO-INOSITOL-1 PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01658">
        <property type="entry name" value="Inos-1-P_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07994">
        <property type="entry name" value="NAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015578">
        <property type="entry name" value="Myoinos-ppht_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0398">Inositol biosynthesis</keyword>
    <keyword evidence="13 16" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0520">NAD</keyword>
    <keyword evidence="12" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="14" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myo-inositol-1-phosphate synthase GAPDH-like" evidence="15">
        <location>
            <begin position="140"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1744375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="361" mass="39931" checksum="0D26B73E3EF37383" modified="2024-05-29" version="1">MKDIKPLPSIYFPDFIAANQGERADNVLTGTKQEQMEQIRKDIRDFKTKNGLDQVILLWTANTERFSAVEEGVNDNAENILSSIEMGEAEVSASTVFAVASILEGCTFINGSPQNTFVPGVVELARQKKVFIAGDDFKSGQTKMKSVMVDFLVSAGIKPVSIVSYNHLGNNDGKNLSAPSQFRSKEISKSNVVDDMVASNRILFEEDEHPDHVVVIKYVPYVADSKRAMDEYTSEIFMGGKNTIAMHNTCEDSLLATPLIYDLVILGELCQRVQVKKEGETEWESFHPVLSILSYMLKAPLVPNGAPVVNALFTQRCAIVNLMRACLGLAPDNHMTLEHRFESTLAAFSSDEPANKKMRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG12</accession>
    <name>A0AAD9DG12_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DG12"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="1">
        <location>
            <begin position="91"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1140" mass="127514" checksum="6A13B66F1204D900" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG40</accession>
    <name>A0AAD9DG40_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoglycolate phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.18" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DG40"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008967">
        <property type="term" value="F:phosphoglycolate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01427">
        <property type="entry name" value="HAD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050155">
        <property type="entry name" value="HAD-like_hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43434">
        <property type="entry name" value="PHOSPHOGLYCOLATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43434:SF22">
        <property type="entry name" value="PHOSPHOGLYCOLATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="375" mass="40252" checksum="DA4A96CDA4A8B764" modified="2024-05-29" version="1">MNLRALPANAYCIASVSSSASSSITMTTINGRGSGLLSVGGASSFTLPATTRVRVASWPPEEWAPKMIVFDKDGTLGECTQALKIWCNRMTEKILYKCLAMNLSREKANFIVSSFYSVIGWSVEKDDVVPSAPLSANSWADILDVTAECLAELGLRVSIDEVACWHESLGDIHVQDPPLINNLAHFLTDLKSQGILISICTSDDRSSTTACMRNWQIEHLVDYCICGDEVERSKPSRQPLLNLCRQAGVMPHECLVVGDTSSDMGMGLNGGAGLVVGVLTGSGTKQQLLDTGAHVVLPNIGHLKDLLRCLPPREVAPSSTTVVSVESDASIDDMRNEEETAASLLVSMKSKDHSLPLKAGKEQTGDNDDDVSVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHT0</accession>
    <name>A0AAD9DHT0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHT0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="410" mass="47306" checksum="6CB16242A888DC72" modified="2024-05-29" version="1">MKEVRVSFGLAREVMLATLIHEYDTFHQKCRDLNIPLENEGLYQHLFGEESRLVTAMKRDLKLDHPTIYEFLATFYFAAEFRSPAKRLQEHSRVNYDGYMDQEPLNKIWRAIADAGKNGESPVYFWQDVESALNEDCREFFLTFSGQRHPIRVAWDDDKVHLQFSTHDVRSDPHFLCGGQAHQHTMSNCRGLTIHSAILAASGFPVGFRTSRQGESEHQCYETLLRFMFAYYFTVSGAAHLGLDNIIFCSDRGYWTPALILLILSFGGTVFGTIKRSYWVPFTYNQKRQDKREQIETKYGRSIFVAFSRWGEYMLKIMAWRGGTGNVSLAMNSDCSEDQLVTMEFKLKNSADAKWYHDKDLTRDQRKLKAFQQISGIDISKEDLDKVDAHIQHSLNVTLTSCGLPFGCLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIU9</accession>
    <name>A0AAD9DIU9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_002614</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIU9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="13"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1747270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="201" mass="22855" checksum="BB3D283C952F8718" modified="2024-05-29" version="1" fragment="single">MNADAESDKMMYCASCGTPEVDDVKLKDCAACKLVKYCGVQCQKDHRPQHKRDCKKRAAELRDEILFKQPESSHLGDCPICCLPLRIDATESTMMSCCCKLICDGCEYANKIREMNEKLDHQCPFCRHPVPKSQEEGNRNIMKRVEANDPAAMRHMGRERWGEGDYDGAFEYWTKAAGLGNIDSHYQLSVMYRDGLGVEKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DK23</accession>
    <name>A0AAD9DK23_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_000574</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DK23"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031519">
        <property type="term" value="C:PcG protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16531">
        <property type="entry name" value="RING-HC_RING1-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043540">
        <property type="entry name" value="RING1/RING2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46076:SF3">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RING1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46076">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RING1 / RING 2 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="62"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="350"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="145"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="440"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="173"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="461"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1748635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="578" mass="67257" checksum="E60BD03F128F7A27" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2020-12-02" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6U3T4J7</accession>
    <name>A0A6U3T4J7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_003659</name>
        <name evidence="4" type="ORF">SMAR0320_LOCUS3599</name>
        <name evidence="5" type="ORF">SMAR0320_LOCUS3601</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="HBGZ01005207">
        <property type="protein sequence ID" value="CAD9581417.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="HBGZ01005209">
        <property type="protein sequence ID" value="CAD9581424.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6U3T4J7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042404956" description="Thioredoxin domain-containing protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="115"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CAD9581417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CAD9581424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1745735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="291" mass="32153" checksum="3CD034F3F004AEA2" modified="2020-12-02" version="1">MNIKEHRRMSAAVLLAVLSTALLATHTVAFSPASSSPKVRAGTPSHLGYRNYDDIIINTSITTEGEAASSPPVTPTKKQPKILKQGSKSATPPRLYDEATFATLDVDADRMPLSILLEPPAPPLTEQLQPNTTTPSRPSSRVTSTASRAATRSSPITQLFNIQDYHQHVLNEPNQLCIIRFHAPWCQVCRTTNVSWERMASKIVKMNSSKRNIKFLSVSLDGKNEEAAELKDMLQIESVPQGVIHYASEGLFGQKVHLNRKNLGVLKKQLESYLTNDMGADMFLYGLKKET</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-12-02" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6U3UIB3</accession>
    <name>A0A6U3UIB3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UDP-sulfoquinovose synthase</fullName>
            <ecNumber evidence="5">3.13.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_010875</name>
        <name evidence="4" type="ORF">SMAR0320_LOCUS7076</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="3.13.1.1" evidence="5"/>
    <dbReference type="EMBL" id="HBGZ01009908">
        <property type="protein sequence ID" value="CAD9591322.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6U3UIB3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046507">
        <property type="term" value="F:UDPsulfoquinovose synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43000">
        <property type="entry name" value="DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042404960" evidence="2">
        <location>
            <begin position="17"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="54"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CAD9591322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1738206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="452" mass="49892" checksum="9752EA97710DCA26" modified="2020-12-02" version="1">MKFFFLLATVTSTATAFTTGFAPSVVTKSASAFSFTLNAEAAAATTNGTDKKKVIILGGDGFCGWPTSLYLSDQGHDVVIVDNLSRRNIDTELGCDSLTPIQSPSVRVQAWKEVSGKDIKFVNLDVAKEYDLLVQLIKEEQPDSIVHFAEQRAAPYSMKNSKCKRYTVDNNVSGSNNLCCAVIDSEVDAHIVHLGTMGVYGYGTSGGEIPEGYIDVILPGGREQNILHPAYPGSVYHATKCLDALLWQFYQKNDNLRVTDLHQGIVWGTNTPQTIRDERLINRFDYDGDYGTVLNRFLMQGAMGVPLTVYGTGGQTRAFIHVTDTARCIEIAINNPPNAGERVEIFNQIAETRRVRDVAEMVAKQTGVEANFLPNPRQEAAENELDVSNKKFCNLGLDPITLDEELFSEVTEVVNKYKHRCDPTKILPASFWNKKRAEECATLDPTSVKVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-12-02" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6V0YI24</accession>
    <name>A0A6V0YI24_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016867</name>
        <name evidence="1" type="ORF">SMAR0320_LOCUS7147</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="HBGZ01010016">
        <property type="protein sequence ID" value="CAD9591527.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000066">
        <property type="protein sequence ID" value="KAK1732473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6V0YI24"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CAD9591527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="144" mass="15898" checksum="23E965FF7C846553" modified="2020-12-02" version="1">MDKSAAAEEDDEFFGDQSCDDEFGAAEAEFRDVKTLSYLDGFDETKEEKLQEGFAEGYSQAFNDAFVAGSRLGSIAAKTALCELNKDTKCVTANQPRLHNAASAIHQFLRDEIMIGDEKARESTYEGAFDNLKNKLDSIESDSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1GY08</accession>
    <name>A0A8K1GY08_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytochrome c biogenesis protein CcsA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 10" type="primary">ccsA</name>
        <name evidence="8" type="ORF">QTG54_017166</name>
        <name evidence="9" type="ORF">QTG54_017267</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="10"/>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2021" name="Front. Plant Sci." volume="0" first="0" last="0">
            <title>Chloroplast Genomes for Five Skeletonema Species: Comparative and Phylogenetic Analysis.</title>
            <authorList>
                <person name="Liu S."/>
                <person name="Xu Q."/>
                <person name="Liu K."/>
                <person name="Zhao Y."/>
                <person name="Chen N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CNS00100</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">May interact with Ccs1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Plastid</location>
            <location evidence="6">Chloroplast thylakoid membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MW679506">
        <property type="protein sequence ID" value="UAM91336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MW679506">
        <property type="protein sequence ID" value="UAM91374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_010200839.1">
        <property type="nucleotide sequence ID" value="NC_058701.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_010200879.1">
        <property type="nucleotide sequence ID" value="NC_058701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1GY08"/>
    <dbReference type="GeneID" id="68637957"/>
    <dbReference type="GeneID" id="68638001"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01391">
        <property type="entry name" value="CytC_CcsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002541">
        <property type="entry name" value="Cyt_c_assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017562">
        <property type="entry name" value="Cyt_c_biogenesis_CcsA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045062">
        <property type="entry name" value="Cyt_c_biogenesis_CcsA/CcmC"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03144">
        <property type="entry name" value="cytochr_II_ccsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30071:SF1">
        <property type="entry name" value="CYTOCHROME B_B6 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30071">
        <property type="entry name" value="HEME EXPORTER PROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01578">
        <property type="entry name" value="Cytochrom_C_asm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="3 6" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0934">Plastid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="229"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="267"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c assembly protein" evidence="7">
        <location>
            <begin position="69"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1732123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1732224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="UAM91336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="325" mass="37100" checksum="43112C77D8DA45C3" modified="2022-08-03" version="1">MDWNITQNFSSNIVFGILLFAMITYWINLSLFRGNKNLIKIGKWGAILANILLFFILCSRWIIAGYFPLSNLYESLLFLTWTLLTIYLYLEFKTKSKLLGAILLPIALLINGFANLTLSADMQKSSPLVPALQSNWLMMHVSMMMLSYATLIIGSLLCILFLVLSKLQDVDLQLVDESTSLVFYNNIFDYYEAKVFLQENKSSTPSELPFEEDIQEIAFLKLLKSLDNWSYRIIGLGFPFLTIGIIAGGVWANEAWGSYWSWDPKETWALITWLVFATYLHSRLTKGWEGKKTAILGGLGFFVIWVCYLGVNFLGKGLHSYGWLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRN9</accession>
    <name>A0AAD8XRN9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_017052</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000077">
        <property type="protein sequence ID" value="KAK1732277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRN9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="76"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="235" mass="26420" checksum="513E396F9BFDB93D" modified="2024-05-29" version="1">MSSEIRRRNVNTSGGEHIVPMATYDETHLSAPALLAASPIHAGFAMKLHVPVFYSFLPSPVQWALSSWCPTGWSPQWKRRYLIALGGYLYRFKDENGSTPKGAPITVDITEARIISRGDTSTSNEFNCLLDLLPDGCDTVFEVSSLAKTQYFAVESREEALAWVNSIRQMRQDSITRNMGHSKGIPYPTQWDSFDASARRLQEQKERIKNRMSALDKKEQEMQTLGGSANMGYFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XS15</accession>
    <name>A0AAD8XS15_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016832</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000066">
        <property type="protein sequence ID" value="KAK1732438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XS15"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.890.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016088">
        <property type="entry name" value="Chalcone_isomerase_3-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016089">
        <property type="entry name" value="Chalcone_isomerase_bundle_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="832"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="441"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="884" mass="99387" checksum="DB8D460AE8EC5956" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XS25</accession>
    <name>A0AAD8XS25_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_016756</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000064">
        <property type="protein sequence ID" value="KAK1732544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XS25"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1732544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="183" mass="21566" checksum="27F53935C2925CD1" modified="2024-05-29" version="1">MGGFDFEWKGKTYDILTEGGCPFFETDEEEQAFEEWRKTPAGIQLFGPVPKDWSEEHYLDDRYPWDADRECRVDVEEIGKEKKHRNNISSDSDDDESYDEADIDWYFYEKCRFNCYRHFYLTDDTHECAKCGVFSCKQCAKGAFKKCSGEGCNEWVCGCDCEYCEYCEEQKEKKKSKGGKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XS84</accession>
    <name>A0AAD8XS84_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein disulfide isomerase 5-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000066">
        <property type="protein sequence ID" value="KAK1732436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XS84"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="211" mass="24708" checksum="6E3E5217893755AE" modified="2024-05-29" version="1">MSIPLTLHWRRMNMSLSTFLPIGVVIAGIWHPRGRLLPRSCTKLPKIAWKISRMYTNTRMKITMRRLKWNCPCWLERLIVWIIMIFVWIRHPCVPYVEVLCGWRGEGCVQWHRTVVEFTHFIAEMEKEHKGHKHADLKTEEIKEIATDRTVQTKEHEDYARALSATRHQHQPSWAEEQHPGCQISASSLSIVHLATFTSKLNLVVTTLPLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSH6</accession>
    <name>A0AAD8XSH6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mitochondrial carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_016530</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000057">
        <property type="protein sequence ID" value="KAK1732818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSH6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45667">
        <property type="entry name" value="S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="241"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="325"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="188"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1732818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="443" mass="48655" checksum="66AD53604C681F28" modified="2024-05-29" version="1">MRIKQQHTRARGSRQWTIVLSTAMLSATVSGFAIPVSRSTRAQQFNAAHDHHHGRCQHHVVLNAKHESVDAPSDDADTQHLSLHTTDDINGQRFLTHAQTFVATITIALALSFSGPLVPDANAGFGPSSGATTSTPPNLIAPKIQDTNDIVNQKKLRQLIGSSLDEKRLQQFSEQLDNLTESLKRLISEDEEEETASTVDGSKTVDKTETKEQKKAELEKARILQQQITDREQLLGTLEKQPYWFNYLAAFIGSVASTLVMHPVDTIKTRLQVKRDDDDEIDFSIVSLYEGLSSNILKEGPPSALYLGVYESVKYSLLPIFGLQYSLLIYLTAGAAGEMIGSIVRAPAEAVKSTIQSGIAPNFMEATSQIFGTEESRKNVIRAWSSSIWRDVPFGAIQLAIFELTKSYILNDPDIDFDSSTLLTEAIIGAFAGGWGGISHKSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTN9</accession>
    <name>A0AAD8XTN9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015928</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000050">
        <property type="protein sequence ID" value="KAK1733369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTN9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="134" mass="15008" checksum="E25FB83DA0950A2A" modified="2024-05-29" version="1" fragment="single">MMAADGYYIYNGLEAVPLGVTRVRIDESLTVIPAYAFYNNRTIEEVECHDRVKTVEGYAFQHCPSLRIVIMPGVEAVEQEAFYDCFALTDVECDMLERIGHHAFAGCISLGSVYLPSAKIVEDRAFSRCKSLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUA2</accession>
    <name>A0AAD8XUA2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015374</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUA2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="105" mass="11230" checksum="FFB08C38508ABD86" modified="2024-05-29" version="1">MIPPGHLNKVDLSEADSSDCRGISAKKRISAFLSIITFSSRTNIYGDRVEQGNVGCGLLAKDSLHGVSCTDYVPRAPFDELLAAISKSPITNQSTEDTDDLSNAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV04</accession>
    <name>A0AAD8XV04_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heat shock factor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_015373</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV04"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000479">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF206">
        <property type="entry name" value="HSF-TYPE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="6">
        <location>
            <begin position="120"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1733846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="225" mass="24855" checksum="246EA53C2621EAFE" modified="2024-05-29" version="1" fragment="single">MKKRTVTAAYASAAVWFPSESATKDKEDMYIKKADAATPPTQAAGAAAAPEGLDLLFAASQSQAEANLKDKESDASGAGAGDGATVPSTITAVSNEPVVGDDEYRDNEPENLATAALKNQEQSFPQDLHEILVIPECQSIVHWLPDGLSFIIADKQRFSSEILPKYFREALLNSFIRKLNRWGFRRVKSRRKGEESSFAHSSFVRDKPWMCLRMKCKSKPTYHKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV94</accession>
    <name>A0AAD8XV94_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015308</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1734050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV94"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052394">
        <property type="entry name" value="LRR-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114">
        <property type="entry name" value="LEUCINE RICH REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="653"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="680" mass="75013" checksum="078FB4288AA5581F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVR7</accession>
    <name>A0AAD8XVR7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">diacylglycerol O-acyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_014470</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.20" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVR7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004144">
        <property type="term" value="F:diacylglycerol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014371">
        <property type="entry name" value="Oat_ACAT_DAG_ARE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10408:SF7">
        <property type="entry name" value="DIACYLGLYCEROL O-ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10408">
        <property type="entry name" value="STEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="287"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="56"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1734597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="364" mass="41217" checksum="79CCAAD7DE7EA09D" modified="2024-05-29" version="1">MTLISQSCAYCDSEEFAIQQQFKKEEEEALLRSPNKKRGTLPNLIFETPTVPLRSMPSGRNLTKMGKSPSGRNLTKMGKSYMKKSDQYPPSKPMHRQASPSYLSDGAHPQNYRACSITYYHFGISNFRLLLDTVSKHGFILDELRFSLQGFSEGFSEAPLDNFPFVSGVEQGMGVNVVGMLLHFINTNATLVVVIMIVWLVMQATITWMKFISYNHANSDYRQNLATHKATLALVKDLDEEGLQISYPMNITLKNIYYFWFAPTLTYQIAFPRTPYIRWGKVVTHTLHLFISATLVAFLAAQVVAPNLDLLIKDLEANKGNLVAMLLYTIDYWEHNQEMVEVIEEKTPKLLATIASIFGASSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVU7</accession>
    <name>A0AAD8XVU7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Class II aldolase/adducin head domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014491</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVU7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051017">
        <property type="entry name" value="Aldolase-II_Adducin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672">
        <property type="entry name" value="ADDUCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672:SF3">
        <property type="entry name" value="PROTEIN HU-LI TAI SHAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="AraD/HMP-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042057966" evidence="1">
        <location>
            <begin position="28"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Class II aldolase/adducin N-terminal" evidence="2">
        <location>
            <begin position="87"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="298" mass="33180" checksum="589C860FE24D55B7" modified="2024-05-29" version="1">MQTSPLASSGTFLAACVLISLSTHVEAFVLSSRAHHYHHHNSSSSSLSSTKSPPIITNEEVSCLNTYPSIPSDLERCFTEREWEQRCSLAVSYRIAYLHDWHENIFNHITLKVDGSDSEPGGPYFLLNDFGIGFDEITASNLLKVNLDGMIIQQSIPADRREINPDKGRVFKPGYVLHSAIHAARHDVHAIWHGILPLSQEASYVLKKGLSFHPFEGSANDESEQPRLVANLGPTNQFLMLEDHGPIVACPTIEEAFHGMYFLTRACKYQMKSFAAVGGDLSRINIPDDESKMRLCDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW09</accession>
    <name>A0AAD8XW09_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="2">PPIase</shortName>
            <ecNumber evidence="2">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_014502</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XW09"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01928">
        <property type="entry name" value="Cyclophilin_PPIL3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF2">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0697">Rotamase</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041773679" description="Peptidyl-prolyl cis-trans isomerase" evidence="2">
        <location>
            <begin position="22"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="3">
        <location>
            <begin position="55"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1734629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="204" mass="22551" checksum="0AF6967BF04C2CFF" modified="2024-05-29" version="1" fragment="single">GAPFLHFKFSILNGLPSLCSCLHPSSLFNTSCLLLFICASSPAIFPSNTMSVTIHTTIGDVKIEVFCDTAPRTAFNFLALCASGYYDGTAFHRNMKGFMIQGGDPNGTGKGGESIWGGKFNDEFHADNKHDVRGQVSMANTGINTNGSQFFITYERQPHLNNVYTVFGRVLDGWDTLDQMERLPVEGEAATKKRNKFRPINRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWD4</accession>
    <name>A0AAD8XWD4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014162</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWD4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1735096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="88" mass="9537" checksum="6B5CE800DBA4E071" modified="2024-05-29" version="1">MIAQNGQVMEMVATDGQIMEMVATDGQMMGILVTIQAGEMMEMVICQTSHRKTAMAAGTMMAAGTTMTATPKKKKSLMKTRVKKSLMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWH1</accession>
    <name>A0AAD8XWH1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lipoyl-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014598</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWH1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="196" mass="22539" checksum="E4AF38240135375D" modified="2024-05-29" version="1">MEFTRVMLRHFPRRLCSSNVVGRTSSITHQRRALSMGFSKNCSINHRGLYQQNIHIRHFSKKDLNGDNSNNKQEEEEGDEIITIINGDRPDYESTSDTSKYTHEVKVEMPDIGDLKGGTIEKWYKQPGDIIYRDDIICDIRTESFTFGMVTDDDFDSMMGKILVEEESGMVDPGTVIFTTFSEDKHHCDDGDKKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXK4</accession>
    <name>A0AAD8XXK4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXK4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027973">
        <property type="entry name" value="FSAF1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053030">
        <property type="entry name" value="Ribosomal_biogenesis_FAF1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28096">
        <property type="entry name" value="PROTEIN FAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28096:SF1">
        <property type="entry name" value="PROTEIN FAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15375">
        <property type="entry name" value="FSAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="222" mass="24672" checksum="DF9F617C64261712" modified="2024-05-29" version="1">MPKSAHKKSQSGGSSSNNDTTQNSGKKRKREVKVVVCPSAFPDFTTVGGSTSRRQQKERGIIPQKDAKETDDGLELDVQQTIREIHKFGATGFQGSQKKTHEKAEYEWLTGRVQKRQKIPTKILVGMRQKALKREERQKKELQESGVVSHQVVNKSSAKAKKKRNNKDDEAKAGPGLVQGVFGSNSRKNKKGNRRSMDAGSFGPAPDVGFMKKGMLRVKRPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYL3</accession>
    <name>A0AAD8XYL3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">L-ascorbate oxidase</fullName>
            <ecNumber evidence="9">1.10.3.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_013568</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.10.3.3" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYL3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008447">
        <property type="term" value="F:L-ascorbate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04206">
        <property type="entry name" value="CuRO_1_LCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04205">
        <property type="entry name" value="CuRO_2_LCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028871">
        <property type="entry name" value="BlueCu_1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF394">
        <property type="entry name" value="FI03373P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00196">
        <property type="entry name" value="COPPER_BLUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042259107" evidence="5">
        <location>
            <begin position="20"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="8">
        <location>
            <begin position="41"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="6">
        <location>
            <begin position="213"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="7">
        <location>
            <begin position="520"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1735862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="632" mass="69032" checksum="F08D21B8E0193A5F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1D4</accession>
    <name>A0AAD8Y1D4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011583</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="567"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="819"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1034"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1222"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1323"/>
            <end position="1351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="119"/>
        </location>
    </feature>
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        <location>
            <begin position="126"/>
            <end position="136"/>
        </location>
    </feature>
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            <end position="652"/>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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            <end position="1091"/>
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    </feature>
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            <end position="1241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1334"/>
            <end position="1345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1351" mass="145716" checksum="C47A6E0473E2FAAC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1K5</accession>
    <name>A0AAD8Y1K5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011195</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1K5"/>
    <dbReference type="Proteomes" id="UP001224775">
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        <property type="project" value="InterPro"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
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            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="628"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="628" mass="70996" checksum="2BB5DF29DF831013" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2L2</accession>
    <name>A0AAD8Y2L2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">S1 domain-containing protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">QTG54_011327</name>
    </gene>
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        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
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            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2L2"/>
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        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
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        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15838">
        <property type="entry name" value="NUCLEOLAR PROTEIN OF 40 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15838:SF1">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="103"/>
        </location>
    </feature>
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        <location>
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            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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    </feature>
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        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="416" mass="46588" checksum="FD5D4F2F83A301C0" modified="2024-05-29" version="1">MSYQQHQRRRFVPPEVGSIHRATVTRIEPYGCFVRLVTDEDSPTISGLVHISQLTAITNNGVKISDVNDVVSLDDQVYIKVMEVTIEQTDDGRQRHKFKLSMKYVHQDTGQDLDPDGEMMEQDLMRSQHRSGSGGGGRNSQNSDQDGTGGANSLLGRSLASNIGISSAIDPGSLILKGKSGSSAGGMGNTKFNGYLLVGEDEGEQAPTASVRDERTTASAANMTNAAPAVRPMGRGRATTLPAWMTRQDDDRLGSMKGEKGPGDDKVDDGSRGDRDRKKSSRRDKHHRHKDRKRSSSKKHSRKHKKSSRRRSRSRGRSRSESYYSSSDDYSRSRSRSPSYKKKRKKSKHRHRHRGDREDYSRSRSRSRSDSRDLDQGEGRGSTSSPSAFNNVEEARAIMERLERRQRVHRTKQEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2U5</accession>
    <name>A0AAD8Y2U5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MOSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_011289</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
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            <taxon>Sar</taxon>
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            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2U5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03473">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042007362" description="MOSC domain-containing protein" evidence="2">
        <location>
            <begin position="36"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="MOSC" evidence="3">
        <location>
            <begin position="197"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1737995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="395" mass="44217" checksum="298763509922EB7D" modified="2024-05-29" version="1">MQHHMTMNRLPPHSILPLSLFFFLAAGFSLQRVSSLSSSSSPQMKYSYQPDKNYDMHITSLHRYAVKGLSGDSINSVTLQEGDGTFEDDRRFALLYAGDKKNNFDQKHPQWLHKDNFLCAFTAPELLATLRTEYEVDSSDGRRLLTVWSRLDNSRQSSSTPLLIADLACQAGRDEASTFFSDLCGKKVVCVCASDITKSQNNHDDNGDSGKTKLSGKHTHQFGNTSSGVKNNNDTRTIHIVNHNTAKQFSNMIQHELKQKYNEGVDGCDNELDSIQLNPTRFRPNVVVDGLEPWLEFDLIGKTIEVVPNQDNNTEGDQSQRHPLRFRITSRTVRCAGIGVDPLQPELPAFDIPKLLTKHFPQHGPYLGVYAVVDQDNGCSGGQICVGDKFRVLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3F6</accession>
    <name>A0AAD8Y3F6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">U7 snRNA-associated Sm-like protein LSm11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3F6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005683">
        <property type="term" value="C:U7 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071209">
        <property type="term" value="F:U7 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006398">
        <property type="term" value="P:mRNA 3'-end processing by stem-loop binding and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039267">
        <property type="entry name" value="Lsm11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21415">
        <property type="entry name" value="U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21415:SF1">
        <property type="entry name" value="U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sm" evidence="2">
        <location>
            <begin position="238"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="412" mass="45599" checksum="77B1A6172C50FB30" modified="2024-05-29" version="1">MSSATPPPPPPVSLGKPSLRHRLESYYSLVAPEAIANKEEWTRKFEIIYFKFGGDHIKETKLADKLAKKYGEQVRLLVAPPHRSQRQQVRAANDGDGRVKKGNVQDELYYKIDEDRINSKILDFTSPQFDAIYALSAPESIVAKTNASIFSLSSSKLDNISKFRALLPECDPQRMEPTVRRQKNNTSTGQTQTAAIASNNTKSNNETVAKKNKKAPLFLAMASSYEKPTSGPLSLLYSILQNRQRVRIMIRYVDCIRGTLTGYLVAFDKHFNMILKDVDEVYGGRVTMDAGAVELAGGGAAEAAQPSKSTLEAQRRKCYPKDGSGGPGPAVKQRYFNQLMVRGDNVVMVWRAENERSIHPRTNKSPASSAYADDLNGGSSGNGKSETEVGTPGSLYYALQRWESQSGRKRHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y509</accession>
    <name>A0AAD8Y509_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_010478</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y509"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006691">
        <property type="term" value="P:leukotriene metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.550">
        <property type="entry name" value="Membrane associated eicosanoid/glutathione metabolism-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050997">
        <property type="entry name" value="MAPEG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001129">
        <property type="entry name" value="Membr-assoc_MAPEG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10250:SF26">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10250">
        <property type="entry name" value="MICROSOMAL GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
        <property type="entry name" value="MAPEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="MAPEG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="112"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1739162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="196" mass="21171" checksum="052EDFEB2EDCF5E6" modified="2024-05-29" version="1">MTTKPLLICLSTASIGGFLELTTASKFTSSHHQSQLTAITPCILIGTGLWTLAHGFTVGKARIKYATLAKKDGEANVDERYLLPNLYAQGTSKHVRAFNCIQRSHQQIFETYTTVVLSGVMGAISFPICTAVSTFVYAVGRYQLSTGYAEAAKEGGDASKRYKYPLAKYMWYGFLCNVLLGMGSCGLIVGGKKTVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y553</accession>
    <name>A0AAD8Y553_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009792</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y553"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="464" mass="51989" checksum="1A6D1AE695D23086" modified="2024-05-29" version="1">MNTTSLRQRARASLTGVGGGRNTSSILPQTHNKLHNECDNENTTETLPRRRKMQRQMKSVIILCLCLCLCLSVGVFFGVVGVRFFGATLFLSSFDNSKNNIISTAASSAEENVFATPPLTPGQVSPLRWSNDNTVVQQYGSRVVLPPQLIPTLTSYVQQLGLLDIMQNMLYENPLQPGDDARWFSFQSPYQKRKDGSSEGIRNFTWNVERPESHWKSDMHWFNTADELAHEDSLRALAKGGFDQVLQGIGAMYGLDTLHVDSVGFVAVTNCERGFMHHDWVDVDGRAFNFLFGIHSPVDSGAELYVGNDEGRRGELQYGSNHGVLVGDGTRHGTKECDHRSHREVRVTCTVYLADVTDDNLAVIAGDSTSIFPPTGDVGVEWTWTQRGRHWNKNGGPSLMEDVGRKSFYVQDDNVGECEKDICLAVKDENDIGEYRNECMRTCEVFMDDRAYRPGERRHDVLGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5T2</accession>
    <name>A0AAD8Y5T2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helicase-associated domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5T2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.530">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005114">
        <property type="entry name" value="Helicase_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33418">
        <property type="entry name" value="HELICASE-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33418:SF1">
        <property type="entry name" value="HELICASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03457">
        <property type="entry name" value="HA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase-associated" evidence="2">
        <location>
            <begin position="315"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase-associated" evidence="2">
        <location>
            <begin position="393"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="478"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="205"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="509" mass="54929" checksum="5719192F168A43FB" modified="2024-05-29" version="1">MMPSQSPSPSGGTAGDTELPPLPNLPPNKRTISLPNNNMMPNSYLTTASEGDWLQKLQLEQNNANGMLSNMGMPSNNFRGDAVKYGFGGDNNSTAAGMANNSGNSASASAEGGGATSSSEREQMVAELRKMQAENEDLIRLISSRQQQQQQLGGSGGSGGGSGGTNGSINPMMMMQQQQQKVGGEGDNNHHQLKNGGNSEGQSKSAAAGGSSTALSPTGGMNMNSAAAVMGGMMGMNNINMMMPYSTMMGGGMNHHDMMNLNNMMPYSTMTHPSMSTNTTNNNNNMMLPPSKSTSTTNNNNNKAQKITIETSEDPNWEERYHELQLFKSEHGHTRVPARYKSNPKLGRWVMTQRRQFTVLMQGFPSALTTERMNRLNEIGFVWALRADPVTMWNRKFGELKAYKRLFGNCMVPQRYQPNPKLGTWVHTQRRQYKLMLEGKKSAMNNEKITALDSIGFFWMAKQKDGGAVAVGETTAVAGAGGSLPPSLPGIEGKSEGYGDDADEGSDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6B7</accession>
    <name>A0AAD8Y6B7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DUF262 and DUF1524 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_009674</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6B7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011089">
        <property type="entry name" value="GmrSD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004919">
        <property type="entry name" value="GmrSD_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35149:SF2">
        <property type="entry name" value="DUF262 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35149">
        <property type="entry name" value="SLL5132 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07510">
        <property type="entry name" value="GmrSD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03235">
        <property type="entry name" value="GmrSD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042232093" evidence="2">
        <location>
            <begin position="21"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="domain" description="GmrSD restriction endonucleases N-terminal" evidence="3">
        <location>
            <begin position="106"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="GmrSD restriction endonucleases C-terminal" evidence="4">
        <location>
            <begin position="651"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1739915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="792" mass="88455" checksum="7D058A479672FB5D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8I1</accession>
    <name>A0AAD8Y8I1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit H</fullName>
            <shortName evidence="4">eIF3h</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_007344</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit H family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8I1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08065">
        <property type="entry name" value="MPN_eIF3h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03007">
        <property type="entry name" value="eIF3h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027524">
        <property type="entry name" value="eIF3h"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045810">
        <property type="entry name" value="eIF3h_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19445">
        <property type="entry name" value="eIF3h_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MPN" evidence="5">
        <location>
            <begin position="14"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1741771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="337" mass="37455" checksum="C739DF5499F4D1CD" modified="2024-05-29" version="1">MAAVIEADARVTSVKLEGLAALKIIKHCQESLPTMVTGSLLGLMIEDGVLEITHAFPFPEPLDDKGDIVKTADEAAVEDEAAALDGHEFQIEMMKMLREVNVDNNCVGWYQSMYLGTHSTSTVFENQLSYQTDLSPNAVVILYDPMQTAHGNLILKCYRLTEEAVQLKQSGKNNFINPRNIFEEVPVTLNNPGLIRSLLRDVGDGLHGPYGAEGSGTDTTFDRLDLSTNPYLEKHLEFLCSWVDDLAAEQYKFQHYTRSLRSNVDSRSKGRKAKEELAQAIDEGWARQDAPKRMESLLMSNQIRTYCDQVEKFTGGGFGKLYLTSGLHGKDDKKAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y975</accession>
    <name>A0AAD8Y975_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cell cycle checkpoint protein RAD17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_007827</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the rad17/RAD24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y975"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004582">
        <property type="entry name" value="Checkpoint_prot_Rad17_Rad24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12172">
        <property type="entry name" value="CELL CYCLE CHECKPOINT PROTEIN RAD17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12172:SF0">
        <property type="entry name" value="CELL CYCLE CHECKPOINT PROTEIN RAD17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03215">
        <property type="entry name" value="Rad17"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RanBP2-type" evidence="13">
        <location>
            <begin position="89"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="116"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="711"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="45"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="61"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="711"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="733"/>
            <end position="746"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1741349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="746" mass="83164" checksum="0BFE790536686C87" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9J8</accession>
    <name>A0AAD8Y9J8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UPF0754 family membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008022</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9J8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35791">
        <property type="entry name" value="UPF0754 MEMBRANE PROTEIN YHEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35791:SF1">
        <property type="entry name" value="UPF0754 MEMBRANE PROTEIN YHEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="441"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="469"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="537" mass="61021" checksum="ECE025B67D7C88F7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9R9</accession>
    <name>A0AAD8Y9R9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Quinone oxidoreductase</fullName>
            <ecNumber evidence="2">1.6.5.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007237</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.5.5" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9R9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003960">
        <property type="term" value="F:quinone reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051397">
        <property type="entry name" value="Zn-ADH-like_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677:SF4">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="26"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="371" mass="39691" checksum="E51FB79B31159479" modified="2024-05-29" version="1">MRAVRVHRFAALDKLGKPCSPAPIRSCLDLDDHVPVPSLKPNKVLISCNYAGIQYPDFLQAQGLYQIKPQLPYIPGMDVAGVVIDKGSDVHDDQIQIGDRVYANTALCPDGGGGTGALAEQVCLSSQAVFPIPDTLHLSSVANIGRNYCAAYHSIKVIGNVGPGDLVLVDGASGGVGMASVELAKARGAKVIAGVSHINKAAMIVNAQAGADKVLVYGRDKESYTKFKKEFKLAAAELGHPEGASVIVDVVNGDLFPALMSCVKPLGKICLVGFVAGQNPIKPGLVLIKEAQVVGSLWGRWARTHPDEFRRNMNEMLTFMAEGTIEPRADSIFDLDDYVKAFELFERNEGRGNTVVCVKSETSFNVQTSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAC1</accession>
    <name>A0AAD8YAC1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphopantothenate--cysteine ligase</fullName>
            <ecNumber evidence="2">6.3.2.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007513</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAC1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10300">
        <property type="entry name" value="CoaB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035929">
        <property type="entry name" value="CoaB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12290">
        <property type="entry name" value="CORNICHON-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102645">
        <property type="entry name" value="CoaB-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="520" mass="57191" checksum="B68A8348FF99C1A2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAG8</accession>
    <name>A0AAD8YAG8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAG8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="448" mass="51259" checksum="407286E750CD71C3" modified="2024-05-29" version="1">MGTDNGNRGRRTKRSKTFHLLLVRILRYVIDTSKRLRCILSIVAITFFTRLFIYSSYKILPSPELLFFDSFDPSSSDLGPSIPAQCKDVIQQVYRCQDEATNTIVLGCHRRWCNSFGHCNECAGIGDRFFNYAMHHIQHAYSGDYPGLLQQQIPSMMQNSNNTTKTCNLKVQFDYPAQGITTVKSAVYQDPAGWLGELFRYRSYMKIGHTFKPQFLLGSTSPPRTIVGHMMSNFDWHSATTRASLPFKTTDWSGCLFHAYFRPNYYLERDLEYHQTQLNGGTAIKDSDTAIISIHFRVGDGLSFKQLELHEDVRLSNSKTLEDGWEEMKQCARELVNSSPEYSDKKHIRFVLASDSLDVKRLARNDAEFDVYTTDITPSNFRQSPSKDADAWMELFLLSRQDGLVMNSVADVKAYKGRVSYASKGSAFSLLVEKIGFFRKHQVRVCKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAN7</accession>
    <name>A0AAD8YAN7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008053</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAN7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="304" mass="33990" checksum="E741DD128EE15DB5" modified="2024-05-29" version="1">MIKRSDSTSKESLMPESSPVTVISDSMVDDNGKLKRNRSILESMHRWLARNGKLVVIVLTCLTLSVFFIPPLKILLRHEGHTTRKQNKTKQSLPEIPPCDKSPWKPSEDLRGKCPGDLKPFPTATTISECASTCCSSDDCISWQFRSDTGCLQGKDVRLGMEKDGVAAWCSDHPPQRWQGQYLIPHKSITQNAQHVLTKEEIRSNGCNEQTWNPDEQIGQCFGLGDVKPKASGSAVECMKACCADEKCGAWQYNQLLGCFYSKGMHGCQGDGNPEKFAPFVGRRKFMEGRTYVDKKGKPWQQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBE0</accession>
    <name>A0AAD8YBE0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Folate synthesis bifunctional protein</fullName>
            <ecNumber evidence="16">2.7.6.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">QTG54_006781</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(7,8-dihydropterin-6-yl)methyl diphosphate + 4-aminobenzoate = 7,8-dihydropteroate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19949"/>
            <dbReference type="ChEBI" id="CHEBI:17836"/>
            <dbReference type="ChEBI" id="CHEBI:17839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:72950"/>
            <dbReference type="EC" id="2.5.1.15"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>6-hydroxymethyl-7,8-dihydropterin + ATP = (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11412"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:44841"/>
            <dbReference type="ChEBI" id="CHEBI:72950"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 7,8-dihydrofolate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">In the C-terminal section; belongs to the DHPS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.3" evidence="16"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBE0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005740">
        <property type="term" value="C:mitochondrial envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003848">
        <property type="term" value="F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004156">
        <property type="term" value="F:dihydropteroate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00739">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00483">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.20:FF:000006">
        <property type="entry name" value="Dihydropteroate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.560">
        <property type="entry name" value="7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="entry name" value="Dihydropteroate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045031">
        <property type="entry name" value="DHP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006390">
        <property type="entry name" value="DHP_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000550">
        <property type="entry name" value="Hppk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035907">
        <property type="entry name" value="Hppk_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01496">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01498">
        <property type="entry name" value="folK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941">
        <property type="entry name" value="FOLATE SYNTHESIS PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941:SF1">
        <property type="entry name" value="FOLIC ACID SYNTHESIS PROTEIN FOL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01288">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55083">
        <property type="entry name" value="6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="Dihydropteroate synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00792">
        <property type="entry name" value="DHPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00793">
        <property type="entry name" value="DHPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00794">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pterin-binding" evidence="15">
        <location>
            <begin position="288"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1742216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="565" mass="61449" checksum="6CD50280EF2D5412" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBH8</accession>
    <name>A0AAD8YBH8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histone acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">QTG54_007060</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Acetyltransferase enzyme. Acetylates histones, giving a specific tag for transcriptional activation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:45948"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000123">
        <property type="term" value="C:histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.20">
        <property type="entry name" value="Coactivator CBP, KIX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1020.10">
        <property type="entry name" value="TAZ domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031162">
        <property type="entry name" value="CBP_P300_HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013178">
        <property type="entry name" value="Histone_AcTrfase_Rtt109/CBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036529">
        <property type="entry name" value="KIX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035898">
        <property type="entry name" value="TAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000197">
        <property type="entry name" value="Znf_TAZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13808">
        <property type="entry name" value="CBP/P300-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13808:SF1">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08214">
        <property type="entry name" value="HAT_KAT11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02135">
        <property type="entry name" value="zf-TAZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01250">
        <property type="entry name" value="KAT11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00551">
        <property type="entry name" value="ZnF_TAZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57933">
        <property type="entry name" value="TAZ domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51727">
        <property type="entry name" value="CBP_P300_HAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50134">
        <property type="entry name" value="ZF_TAZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="22" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10 14" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 22" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 15" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TAZ-type" evidence="20">
        <location>
            <begin position="1185"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="18">
        <location>
            <begin position="1528"/>
            <end position="1600"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="19">
        <location>
            <begin position="1672"/>
            <end position="1750"/>
        </location>
    </feature>
    <feature type="domain" description="CBP/p300-type HAT" evidence="21">
        <location>
            <begin position="1761"/>
            <end position="2200"/>
        </location>
    </feature>
    <feature type="domain" description="TAZ-type" evidence="20">
        <location>
            <begin position="2199"/>
            <end position="2280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="165"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="206"/>
            <end position="265"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="304"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="390"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="447"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="516"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
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            <begin position="662"/>
            <end position="690"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
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            <begin position="729"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
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            <begin position="822"/>
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    </feature>
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        </location>
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        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
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        <source>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAK1742495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2311" mass="257811" checksum="0F9F251A541075E1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YC05</accession>
    <name>A0AAD8YC05_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetylgalactosaminide beta-1,3-galactosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.122</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_005258</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.122" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YC05"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016263">
        <property type="term" value="F:glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026050">
        <property type="entry name" value="C1GALT1/C1GALT1_chp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003378">
        <property type="entry name" value="Fringe-like_glycosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033:SF47">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033">
        <property type="entry name" value="BETA1,3-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02434">
        <property type="entry name" value="Fringe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fringe-like glycosyltransferase" evidence="12">
        <location>
            <begin position="87"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1743661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="341" mass="38232" checksum="424ED1FB839181B3" modified="2024-05-29" version="1">MSGAGPDFLTAAVSYFDDPDVVFVHKQHLIQGPVTNQSVTHHDFDATWLCDGELCDGVKESVKDLGNQDAEMLSHNRTLPNSDTQHHHKLLILLRTGSSNSTSRVQSIKQTWASGLADGQLRIMEGNERCLRKYGDNHWEGLTCLEATNHIEIMNSTLTNFTWLLIVDDDTYVVVDRLTNLLDRLDPHQPAAYGAPGCGNCGQNRTGFCGGGGYFISRTNLLRMAGLRDRPVLPSVAHAFIEHFMQEPDSVWCDVRFGCVAQDMGLRLIDQPGLYGNPVKDENEEKRIIRLEEGYPPLVFHKVSNHSQMHRIHDLVVEMTSKNGTWTKIVEDPDWHSTVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YC53</accession>
    <name>A0AAD8YC53_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RCC1 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_005333</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YC53"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051553">
        <property type="entry name" value="Ran_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982:SF1">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13540">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="RCC1-like" evidence="5">
        <location>
            <begin position="2"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="7"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="57"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="209"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="RCC1-like" evidence="5">
        <location>
            <begin position="375"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="398"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="448"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="603"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="823"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="873"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="258"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="690"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="703"/>
            <end position="716"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1743736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1055" mass="110948" checksum="183A7802B983ABAC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCK1</accession>
    <name>A0AAD8YCK1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">N-acetyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006413</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCK1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031415">
        <property type="term" value="C:NatA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000006">
        <property type="entry name" value="Putative n-alpha-acetyltransferase 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051556">
        <property type="entry name" value="N-term/lysine_N-AcTrnsfr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42919">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42919:SF8">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="6"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1742816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="167" mass="19147" checksum="334930A9DD409059" modified="2024-05-29" version="1">MGKLSIDFGMINSDNIEQLKKINQACFPVAYGDSFYRDMAKKSDENLCKFAYYSGLAIGAVCTRVEPIPDDPNGRSRLYIMTLGVLAAYRNHGIGSKLVESVMEYYESEKDGKLSTVDEIMVHTQTSNMDAMNFYMDRFGFEKGELVENYYKRIDPPHCYVLRKKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCT5</accession>
    <name>A0AAD8YCT5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005389</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCT5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1743792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="474" mass="52478" checksum="FB893AF7B7F42512" modified="2024-05-29" version="1">MLQTILANSILTDGASAFLPRNAEIHMATGPMDTTIFKLTSVNREVLSQCRPKQNTAASQSTNIDVDVMTNDKQTEANDKLTKEDSICTSMQPTDPEWLEAIEQTIESRLAKQVAKAKQLERTTQVQSDLIHKGRETIHKAARLNSTGGSLDNDPQILRLRYGTRPRTVSDTQKGLSAVIDLELDMHLPHQRESKELHDFHVSCTLASKLEQNITSVDNIRTQSGVVAVFQDGNCITILASLLLNELDLDFQTNRNSTSTLDFNIQGLWLDEMQKRQGSVLCILRLPLNGILFSPMSSATRAGHCIQHEIDFTSADKNHASRLVPSAIFDYRHPRTLNIDVSGSIGLQDGTIWKDLVSKLNRQIGMSSCIDLYYIKGDPTLKLVIFASNPAELAAITNLVLQNLPNNAKIFEQDPDEAKNVKTLLASLKNEAAAFQKHRTIMSKGTVTAEMRKEMSSLQASTDGVASTIKRGWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDP4</accession>
    <name>A0AAD8YDP4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">D-amino acid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDP4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038732">
        <property type="entry name" value="HpyO/CreE_NAD-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13454">
        <property type="entry name" value="NAD_binding_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding" evidence="1">
        <location>
            <begin position="86"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="373" mass="41960" checksum="0AED4D7CA4782BF4" modified="2024-05-29" version="1">MDIQYASHSNILHQTGFWQSCFAAFGIAPLIRPPPMICHYYRDLLSKPRSSGSSVFAVNKINDKSAADFIETTPHYVDLTSQPRIAIVGGGIAGVTAANALCKKLSSNNVTAKIVIFEGDEYGSNNEVDFSNHQQPSWLAATARNANTICPGASFHVMSQRSTLIKIMKDTVREWYEERQNWPQKENLAADHLLRSDNFDYPPPYFALHLFRCVGPSASWDERATFLTFLTSFLKTSLFSTEHDVHERGKLIYQLAKSNRVLFLGAMNDSSVLASKTGLSRGFISLYRSRQDAMHDFQEGESFGEDFALLSYEEAVKLEARIKNLPISEEVVAVHRKADYTADCAAFIKDLTNKITQEYGVEYKMVFKGRFMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YE32</accession>
    <name>A0AAD8YE32_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005349</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YE32"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042258258" evidence="1">
        <location>
            <begin position="25"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="277" mass="30885" checksum="A2A838FF992B10F9" modified="2024-05-29" version="1">MKTTRLQAVGLLLPLLLLIAEASANIFSNDAGITFNQHRRSYAHDLLKKLRYGSADTFSFGRFQSPHAIDKAMSECRSAKSFKRHSSKDGKEGYYCSTRLGGDWVLAESKQVAKDCVPAEVLAAYLDGSNQKKWNEDKVLDINIARSGSGLYRQDMVLKPQRVLTGKTTIMRYTQKICVDKVGNGNYNAFVELDTKSKSNTKLRPFHILKVNVGLEQVGNDVHIYAAGIMKVNRKIVPNLLIFDASGIAGAMAGKGTLWLSKHFQDRSTKIRNNRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEA1</accession>
    <name>A0AAD8YEA1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Chromodomain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_004215</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEA1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051219">
        <property type="entry name" value="Heterochromatin_chromo-domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22812">
        <property type="entry name" value="CHROMOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="4">
        <location>
            <begin position="32"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="JmjC" evidence="5">
        <location>
            <begin position="221"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="654"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="660"/>
            <end position="669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1744924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="693" mass="78733" checksum="76AB7FBB2DB257FE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEJ2</accession>
    <name>A0AAD8YEJ2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEJ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="258"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="438" mass="48859" checksum="843409E0D4247246" modified="2024-05-29" version="1">MKRQHHKHRNKKKKKGKSSAFAKTILTCCCCPIVIAASSSNQKPPPHRLYQCAHYPQHELFSSDYNICNHRKRVRIKHQQQQFSLNLILECRGGDSMDDMYSYTHNQRADVVSAAATAIQPSTTYNGIYDEGRHDFNSHNTHSALHNAASNNEVNVINTSSTVTNNNQLNGGSSQPNDITESDTSTNQSLQNQSIISPSNQQQQRQRLMVEFDTQAIGNSDRFGNSIRSRIRSRIGNDNDWDRIMRQQRRGAALSISLDLSPSSSSSSSSSGGNSGGGTIGKSDWDIVVLSVAVRCWMFMILAGDVVGPLVLGMSGMDIRQDIGMVGTSKREGDGLVVWSHLDWGGGWDWTCFTVALSVWGGPLRLQAVAVQAEKPKQLLQRVMHHPIKWVRELEEWKHLPDLKPKISRKDGARRRRGGNGSRALDLDPCYSLRLGYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YET8</accession>
    <name>A0AAD8YET8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphatidylinositol N-acetylglucosaminyltransferase subunit A</fullName>
            <ecNumber evidence="5">2.4.1.198</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_004497</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.198" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YET8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000506">
        <property type="term" value="C:glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017176">
        <property type="term" value="F:phosphatidylinositol N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013234">
        <property type="entry name" value="PIGA_GPI_anchor_biosynthesis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45871">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45871:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08288">
        <property type="entry name" value="PIGA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="417"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="PIGA GPI anchor biosynthesis" evidence="4">
        <location>
            <begin position="70"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="3">
        <location>
            <begin position="216"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1745206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="465" mass="52266" checksum="0CEBD02DA9F9CDF5" modified="2024-05-29" version="1">MAQSHQLQRRRFSIAMVCDFFYPRLGGVENHIWSLAFHLLRLGHKVIVITHAYKCPDNEYSNEDTTIRQKSKRSGVRYLPGGLKVYYCPFLPMVDEDCMPTFTVSFPLLRWIFIREAIDIVHSHQATSTLANEAVTYAAELGLASIYTDHSLFGFDDIASVILNRVQKVTMSTVGAVICVSHTCRDNFILRAKLPPSAVHVIPNAVDPAKFTPDTTKRDNNRITVVVVSRLVYRKGVDLLVGIIPIICKTFPQVDFVIGGDGNKKLALEEMVERERLQDRVELLGFVPSGSVRDTLVRGHVFLNCSLTESFCIAILEAASAGLYVVSTNVGGVPEVLPPDMIHLSDPNIDSLVEGLSVAIAEKIDLVDPYEFHQRVSEIYSWHRVARETELVYANVFEKPRLSFLQRLARYKTVGGVAGYVACILAITLHFVVSLVEWWQPVNLIDVIPDMCLVHDENEKKKKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEX5</accession>
    <name>A0AAD8YEX5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004379</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEX5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11340">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="135" mass="15198" checksum="BE5E9A5F94C361C9" modified="2024-05-29" version="1">MITVKPPSNLGREDFKRSSTVADRPKIKSVVNDESTSRSNSNVPPQKTSIEHFLSIQGASLDTKNSEIYQPIKTGKRLLTYKRFGGRLNNQLFQFITALQHAKVLKRTLVVPDEVREVDWTGMFDTAYGFGILIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YF88</accession>
    <name>A0AAD8YF88_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004059</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YF88"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053199">
        <property type="entry name" value="cDPG_synthetase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42869">
        <property type="entry name" value="SLL0572 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42869:SF1">
        <property type="entry name" value="SLL0572 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="148" mass="16220" checksum="F67EE49B06B40491" modified="2024-05-29" version="1">MTEKVIILGAAGRDFHDFMSYWSLQPNVSVVCFTSTQIPGIGGRLFPPEMCNNHKNGNSYPNGLMIYDQNDLEALIEEHGATMCALAYSDISYDSVQSLAARVNSKGCKFIQVPPSLTQLHSSKPVVAICATRTEQARAKLHEQSPTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFV7</accession>
    <name>A0AAD8YFV7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acid phosphatase family protein</fullName>
            <ecNumber evidence="2">3.1.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFV7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010036">
        <property type="entry name" value="MDP_1_eu_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17901:SF14">
        <property type="entry name" value="MAGNESIUM-DEPENDENT PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17901">
        <property type="entry name" value="MAGNESIUM-DEPENDENT PHOSPHATASE 1 MDP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12689">
        <property type="entry name" value="Acid_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01131">
        <property type="entry name" value="C1.5.2:_MDP_Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042209191" evidence="1">
        <location>
            <begin position="23"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="281" mass="30263" checksum="4A53BA2022FC551E" modified="2024-05-29" version="1">MAATSRALQRLSFSSAALLVVGCCCGGSKQALLAQHSSFNMGKGSSGFSATASASSCNSNNVLMPSMIVFDLDDCLWTPEMHELSGMPSIPVEGPLDPSDNNSELGTVGMKVPSRRRRGNNNKGFDWGGYANDDGEEVVELYPGARLVLRELATNPKYAAVKIAVASSSLEPSYSRACINGIEIVDGVTMEDMISYSQIGREGQLTSRKTSHFKLLQAQSGIPYDEMLFFDDCNWGDHVGDLQDAFGVTGIRTPQGLQVAEFHQGLEKLEVEESNIVNAYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFZ3</accession>
    <name>A0AAD8YFZ3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFZ3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="367" mass="40528" checksum="89CE2E9EA58D78A4" modified="2024-05-29" version="1">MVFCPCRKTTTTSIENTNTTTTPNTTKKRFHLFHRKQSDLAYIATELDDDDEIAPTPAELKRLKSVKRSKAHVDGVLYRNRNSGRKTLLTGDGVVNFAGFTDWFHRKRLREKQENGERYDRDEDGKHNGGGGNEGGTTMIVRVQKIDPVKSGFMGKKTDRDETTGCAAGTMVAAQWAGRRPPSRPELLVTPRKGAVNIGCTTAGCGADDSFATAATGCSPMSTGSVSFQEDNSPVHGNAKRLEEGRDDLDENAWCGAFNSSILTEELTASESKESIEDYSRNVPNTDEESVWCDVFNSTTIVTEGEGEGEVTNEEEDDDDSEDEAENSSSSKIRGIQNVEVIYSEKQSMMKRASTWKKKEDSFDQLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGC2</accession>
    <name>A0AAD8YGC2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Heme-dependent peroxidase</fullName>
            <ecNumber evidence="10">1.11.1.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_002686</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the peroxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.7" evidence="10"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGC2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140825">
        <property type="term" value="F:lactoperoxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00314">
        <property type="entry name" value="plant_peroxidase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 10" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042202459" evidence="8">
        <location>
            <begin position="27"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="9">
        <location>
            <begin position="238"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="98"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="182"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1746079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="556" mass="64500" checksum="A152BC99B437125D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGE4</accession>
    <name>A0AAD8YGE4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">E3 ubiquitin-protein ligase, SHPRH family</fullName>
            <ecNumber evidence="9">3.6.4.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_003717</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18070">
        <property type="entry name" value="DEXQc_SHPRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052583">
        <property type="entry name" value="ATP-helicase/E3_Ub-Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45865:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SHPRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45865">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SHPRH FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="1464"/>
            <end position="1505"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="1545"/>
            <end position="1697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="43"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1745793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1706" mass="191003" checksum="C11A2F247B9D5D33" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YH79</accession>
    <name>A0AAD8YH79_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome c oxidase assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_004346</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SCO1/2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YH79"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02968">
        <property type="entry name" value="SCO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000013">
        <property type="entry name" value="Blast:Protein SCO1 homolog, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003782">
        <property type="entry name" value="SCO1/SenC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12151:SF5">
        <property type="entry name" value="AT19154P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12151">
        <property type="entry name" value="ELECTRON TRANSPORT PROTIN SCO1/SENC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02630">
        <property type="entry name" value="SCO1-SenC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="3">
        <location>
            <begin position="78"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR603782-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR603782-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1745055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="211" mass="23871" checksum="B563CF315430F160" modified="2024-05-29" version="1">MGKIVSSESGWSPNPELLARRQYVRTKWGWFPKEDAFGGAGKPAIGGPWSLVDLDGNLVTNESFKGKWTLLYFGFARCPDICPSEMVKIGKVMDTLEKEHPKLRGQIQPIFVSIDPARDSLKALRDYAKDFHPSYVFLTGAPQQVQAMAKKYRVYMSKADETEDGDYLVDHSIVVYFHDETGDIADCFTQSMRPSDIVEKVVERMTFVPSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHA3</accession>
    <name>A0AAD8YHA3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Hydroxylysine kinase</fullName>
            <ecNumber evidence="8">2.7.1.81</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_004462</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the GTP-dependent phosphorylation of 5-hydroxy-L-lysine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(5R)-5-hydroxy-L-lysine + GTP = (5R)-5-phosphooxy-L-lysine + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19049"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57882"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58357"/>
            <dbReference type="EC" id="2.7.1.81"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aminoglycoside phosphotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.81" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHA3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047992">
        <property type="term" value="F:hydroxylysine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050249">
        <property type="entry name" value="Pseudomonas-type_ThrB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21064">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21064:SF1">
        <property type="entry name" value="HYDROXYLYSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="10">
        <location>
            <begin position="69"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00036820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00040505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1745171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="199" mass="21854" checksum="D625CB16F9ABA4DD" modified="2024-05-29" version="1">MSHALDDLAASDKDVLQASKTYHAWDGRHMVDIEPYISHLDGNDQRNLVTSIIASFKKEIIESGEGEKFRMSINHADFNDANIIVSSDGTGIKVSGVIDFGDTVYSWKVLDVAVAMTYALISSYGKSGQSISAACAILRGFHHVYPLTAQERKHLRLLVACRLATSATFGNYTYKLNPENKYILYIPSLPGTHLISSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHI2</accession>
    <name>A0AAD8YHI2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ODAD1 central coiled coil region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_003563</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHI2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035253">
        <property type="term" value="C:ciliary rootlet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097542">
        <property type="term" value="C:ciliary tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036158">
        <property type="term" value="P:outer dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049258">
        <property type="entry name" value="ODAD1_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033192">
        <property type="entry name" value="ODAD3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46518">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46518:SF1">
        <property type="entry name" value="OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21773">
        <property type="entry name" value="ODAD1_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ODAD1 central coiled coil region" evidence="4">
        <location>
            <begin position="128"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="238"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="454"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="517"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="31"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="123"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="240"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="267"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="467"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="524"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF21773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1745639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="576" mass="65790" checksum="274148F69B78B218" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHI8</accession>
    <name>A0AAD8YHI8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHI8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="102" mass="10819" checksum="40ACC3061285489D" modified="2024-05-29" version="1">MSSNNDQERTKSGGDENNNSLSGSGASLPLRKRKNMDRKGAAKKSSSKPIDGKPSSATASSKGRGRGGGKPSHNDDVDPKDPIVDKKFFDGFVDDFDLSDMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YI62</accession>
    <name>A0AAD8YI62_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DOMON domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003459</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YI62"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041969163" description="DOMON domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="783"/>
            <end position="803"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="804" mass="86672" checksum="1D7FF37D900171AA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIU3</accession>
    <name>A0AAD8YIU3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sulfurtransferase-related protein</fullName>
            <ecNumber evidence="3">2.8.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002936</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIU3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd24138">
        <property type="entry name" value="TtcA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43686:SF1">
        <property type="entry name" value="AMINOTRAN_5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43686">
        <property type="entry name" value="SULFURTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal" evidence="2">
        <location>
            <begin position="773"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="477"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="636"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="967"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="477"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="653"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="704"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="740"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="967"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="996"/>
            <end position="1006"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1079" mass="118129" checksum="D889DC9C667FD0C8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJ99</accession>
    <name>A0AAD8YJ99_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002813</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJ99"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="418" mass="48505" checksum="E8EA4A3BA53F5D56" modified="2024-05-29" version="1" fragment="single">MGKKGKKKGASSATKAEKEQKRVARLSLIDKYGRMPREDGIKFYALLDFVAHIVIDDVERERRMNDSDCIPLHWPDRDGLQRMPDSTRTIVLSYIWKHINRITDEIDDGVHDGLFLRKVGRRIQDADKDEIRSWRNHIEDDFVVINHVPHVGSIFVQVGRVVEFEQKGLGPVKDDADIHEPRVFCVQGLATSMQEMCENSHGMLVKAYPSLKKYDLPVSFLHTTLLQYNKGITYAVTAEQTNRSYYETAQQYAEAVKIAHECYKAAILKDQTTNVQCKLYDTITPDIVRRAWEKGTNSSYEHEKWLRDEVRPDDRPNDPEMSCLLVHGMIWMPFANSAHFTDPRTMTVIQEIMSERPMKVIREGFKHRITYEVWFNDHEPCPFHRRLGADDVVTPSFAECCKKDHLKRVAKAKKRDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJD5</accession>
    <name>A0AAD8YJD5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002858</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJD5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="262" mass="29905" checksum="D31371BC2367CFFE" modified="2024-05-29" version="1">MSGFWKQMDRRASISAYNYNLGDEANPEHIDLTKTNQYAAYKVKKLDVGDNVFIRGSNDEWYFAKLTEKSSDEDGNVYTYQIGQDHKFKSLREHQLGDVRLVEVRSQRASHPKLDINQSSSCESYTDKVVQSNHQKKLSSQTNIDIKKSKSAGGGDDKENVPHPNKCYEATRSVAVSELSMASPVENVMKQRVLLALHNLEITPRKPRHQQAVDLNREASHVYQNQLAHAIQISTPMLKQRLTKLGLCSNQELRVFHHVVFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YK39</accession>
    <name>A0AAD8YK39_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_001431</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YK39"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050835">
        <property type="entry name" value="ABC_transporter_sub-D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384">
        <property type="entry name" value="ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384:SF59">
        <property type="entry name" value="LYSOSOMAL COBALAMIN TRANSPORTER ABCD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06472">
        <property type="entry name" value="ABC_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="87"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="35"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1747468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="439" mass="49537" checksum="52E8E6A1F0EE54E4" modified="2024-05-29" version="1">MDSNFIQMAASKSADEEQGSPTRRRTAFTALDTESPLQSDENTHHQPLQGTGGEKKQQTSLREQLHSFRIMSAPYFRESKEGKCLFAIMVVLSLANSAVKVAFSYLSRDFWSALSNKEEEQFYGIMARFLAACLALAPIAVAFRYQRQKLAIAWRKWLTGRVLDLYFSNKVYYALERQLGGGVKSSDNDETAVLAGQTNKEVDNPDQRISEDIRSFTEFSLTFFLTLVTSFIDLVSFSFILFSIMPSLFLAIFGFATLGTFLTICVGKVLIRLNYESLAKEADFRFSLVRVRENAESIAFYAGEAVEEKATFRRFALVIGNMTQINFAQMKLDFVTTFYNYVTWILPVVVVAPQYFAGNVELGVISQASAAFGHVLSDLSIVINSFNDVSKFSAGIDRLYSFMNAIKYLIQIETLDHCSCQLHPLGMLHCWVDILERNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLG6</accession>
    <name>A0AAD8YLG6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_001657</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLG6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042032227" evidence="3">
        <location>
            <begin position="21"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1747694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="157" mass="17802" checksum="210A8917BF6889AE" modified="2024-05-29" version="1">MFVYGHLLVLMGALASCTSGFQISPTRSRTRSVGQQSFLPRLHPASIPPEHNFLYSNNSDDEEPESIKEDLGETNNTVRDATFSIFKLFSYCIQFLGAFFFTGFILNLAGFGYTVDLEHGIVVDRIENIRNEIQFEREIERETLQGSKYLIAPKVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLJ1</accession>
    <name>A0AAD8YLJ1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLJ1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="515" mass="58450" checksum="00C6090FBA3A6DF0" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLQ5</accession>
    <name>A0AAD8YLQ5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001777</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLQ5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1048" mass="115973" checksum="7A0E6A323775EB10" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YM02</accession>
    <name>A0AAD8YM02_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001768</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YM02"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75011">
        <property type="entry name" value="3-carboxy-cis,cis-mucoante lactonizing enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="395" mass="43142" checksum="A1B8E0E2FE432DA6" modified="2024-05-29" version="1">MERSGCRSGLWVDGDDTKMRNGTCPENIFSGSVSSSSCSKTASEQKTSSPPLLGSASLAVELTRDAERSSIGKNIIVAEWGEKRIVRVEGETGARTPLVVLVPPPAHHEKIEMESQGQEEEEEASHESEEVSVPEWVRVQRPNHLTYTPFGDLLFSDNRDSVGVVYRLKEAVHVQPISAEQSRDAHGWERSTMEDQADQNNFDILFQTDGVIEGLALGSDYSMLYILVASPVGKTVYRLPLDSDDDEDDGSGDASSNEANEGEKESASVFYSMPFEDCEEDHIDYNGNASLSVGSKLSVDAQGTLYMITCPSTVTLLSREQGRVIGTLTSQGSKSFTSIGFGEDGYLYLTSPNELRRVKTRIGGMAVPTNLVVPQPSKLATTGGDEQRRQKRDKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YN23</accession>
    <name>A0AAD8YN23_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nucleotide-diphospho-sugar transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_000413</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YN23"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005069">
        <property type="entry name" value="Nucl-diP-sugar_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF98">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03407">
        <property type="entry name" value="Nucleotid_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleotide-diphospho-sugar transferase" evidence="3">
        <location>
            <begin position="326"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="720"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="723"/>
            <end position="760"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1748474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="760" mass="84253" checksum="62B27D1302DF7F55" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YNL4</accession>
    <name>A0AAD8YNL4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SPFH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000476</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YNL4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03407">
        <property type="entry name" value="SPFH_like_u4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050710">
        <property type="entry name" value="Band7/mec-2_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327:SF31">
        <property type="entry name" value="HYPERSENSITIVE-INDUCED RESPONSE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327">
        <property type="entry name" value="STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="1">
        <location>
            <begin position="9"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="288" mass="31812" checksum="7BE16DB22500556C" modified="2024-05-29" version="1">MDPLWTGCFCLQCIREKEVGVVEDLGQFKRLVKEGPSCIVWPLQSVVGRLSLRVQQLDVLCETKTKDNVFIQVGVAVQYRVVTEAAYDAWYRLTSPTSQIQAYVFDVIRSTVPRMELDEAFESKDDIAGAVLEQLQSVMKDYGYAIVNTLVTDLAPDSKVKASMNEINAARRLKEAASHQAEADKVRQVKNAEAEAEARYLSGMGVARQRMAIVQGLQSSVAEFSQEVEGATPKDVMDILLLSQYFDTLSTVGANSLILEHDPATVAKLQRQVGVSFLRDGSGKDLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPL9</accession>
    <name>A0AAD8YPL9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Sodium/hydrogen exchanger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_001016</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPL9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015386">
        <property type="term" value="F:potassium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015385">
        <property type="term" value="F:sodium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051453">
        <property type="term" value="P:regulation of intracellular pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098719">
        <property type="term" value="P:sodium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018422">
        <property type="entry name" value="Cation/H_exchanger_CPA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004709">
        <property type="entry name" value="NaH_exchanger"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110">
        <property type="entry name" value="SODIUM/HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110:SF187">
        <property type="entry name" value="SODIUM_HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01084">
        <property type="entry name" value="NAHEXCHNGR"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0915">Sodium</keyword>
    <keyword evidence="8" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="290"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="324"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="353"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="386"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="505"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="667"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="695"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="783"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="821"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="11">
        <location>
            <begin position="288"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="584"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="902"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="947"/>
            <end position="968"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1749077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="968" mass="106857" checksum="985438F444A2AFAD" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D463</accession>
    <name>A0AAD9D463_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_016215</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000054">
        <property type="protein sequence ID" value="KAK1733077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D463"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="159" mass="18467" checksum="701029AE1BD4416B" modified="2024-05-29" version="1">MKNHQGTSKQVTFSEASKLYTYHEDRPQRERLFYNKRDYDAFRENASTAAFHLRRQTEASLDDESSTLYETESWLPSPQILEEADASIEPEEVLIGLEGKTTSERIMRLFDALKRNHRMWILSEQNHPGRLRGMISNVSTVSSYIAHCKAKNIANYSSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4D1</accession>
    <name>A0AAD9D4D1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016710</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000063">
        <property type="protein sequence ID" value="KAK1732569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4D1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052201">
        <property type="entry name" value="LRR-containing_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24111:SF0">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24111">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="515"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
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            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="211"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="222"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="524"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="535"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="618"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="635"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="645" mass="69062" checksum="721C986ABBB511A8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4I6</accession>
    <name>A0AAD9D4I6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016618</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000060">
        <property type="protein sequence ID" value="KAK1732719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4I6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36489:SF2">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36489">
        <property type="entry name" value="PROTEIN-COUPLED RECEPTOR GPR1, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="228"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="318"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="375"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="392"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="408"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="470"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="510"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="534"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="550"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="574"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="598"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="614"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="638"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="662"/>
            <end position="690"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="913" mass="90270" checksum="42886AC27FBA3C52" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4J2</accession>
    <name>A0AAD9D4J2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sel1-like repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015882</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000049">
        <property type="protein sequence ID" value="KAK1733467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4J2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="158" mass="17215" checksum="DA6BFDDE98F6F4E8" modified="2024-05-29" version="1">MKRANANDPVALLQMGVRRYGDGDYDGAFRYANKAAELGDAGAHYQLACLYFEGKGVEKDEKKAVYHLEQAAIGGHPLARYNLGANEKNNGRMDRAVKHWIIAAALGHDASLDAVKDSFRSGLVSKEDFAAALRAHQAAVEATKSPQREAAEEEARKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4W6</accession>
    <name>A0AAD9D4W6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015429</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4W6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="305" mass="32111" checksum="508D24AE2CC27B0B" modified="2024-05-29" version="1">MVGNDEPDIIVGGQSAPPIATAVPAGGDPLAAPMATAVPVTAFNNPNKNIERTTNADGSIAIKATTTSRQSNGYRDVTIEYFYVPANMAGTVIMSMDSTGEPPSSLYLTKMEQQVLPPGTGEVMSHAPSSAPQTMAGATAAAGFGGGRNNPVSQPYTCENSVVGGRVRRCAAVFGCVCIIIVAVGIVNGVIEMNDTQNPIYLPPTYAPYPWPPYQWTSPTPTPARCKDTPGWVDQYGFECDWYVSSFSNMCGLSQFNQGPMGPADKNCCACRGGSTYVAPMPWPSRAPIISPPSTAQHKGSPYED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D523</accession>
    <name>A0AAD9D523_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">Cysteine dioxygenase</fullName>
            <ecNumber evidence="2 9">1.13.11.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_015991</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-cysteine + O2 = 3-sulfino-L-alanine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20441"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:61085"/>
            <dbReference type="EC" id="1.13.11.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="9">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the cysteine dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.20" evidence="2 9"/>
    <dbReference type="EMBL" id="JATAAI010000051">
        <property type="protein sequence ID" value="KAK1733274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D523"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017172">
        <property type="term" value="F:cysteine dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019448">
        <property type="term" value="P:L-cysteine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10548">
        <property type="entry name" value="cupin_CDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010300">
        <property type="entry name" value="CDO_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12918">
        <property type="entry name" value="CYSTEINE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12918:SF1">
        <property type="entry name" value="CYSTEINE DIOXYGENASE TYPE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05995">
        <property type="entry name" value="CDO_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 11" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="3 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0883">Thioether bond</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="cross-link" description="3'-(S-cysteinyl)-tyrosine (Cys-Tyr)" evidence="7">
        <location>
            <begin position="146"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR610300-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR610300-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1733274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="258" mass="29520" checksum="972CA51171411D12" modified="2024-05-29" version="1">MSSPTSIFSYDLASWDINSSSKNPSSHRPSFTNDTEDSSPITLNQLIQKLPPLLHSQNTKLQQMSIQERIHFDTTIRGTDADAVNQLFGRLDLTKEECWKKYALFDTSKNYTRNLIATDDETFTLLLLCWNAGRESPIHDHPCDGCWVRLCQGRVRETRYESNDETDTLEVTSDVILEDDAPTFINDIKGYHKVGNPDPTLPAVTLHLYCPPFQRCKIWMKDCNNNLRASNACMCYYSEYGVRLGDDKCEDLFEVVTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5X7</accession>
    <name>A0AAD9D5X7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5X7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="146" mass="15945" checksum="0CDDD523CFD54710" modified="2024-05-29" version="1">MLKAAYQRLVGSSSGTDNDERIVSATATPPTGYGSTFSQQSEEQENIIPESIRVRRSLSSSSSTNRRQHSWKLIRNSLISRNTTNESGDTTSPGADFVDIAESVFSDIRSESAASQLAISNEAEDYGLCTAYERAFPNDPLHYSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6R4</accession>
    <name>A0AAD9D6R4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sel1-like repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_014399</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6R4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="133"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="205"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="8">
        <location>
            <begin position="514"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1734939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="702" mass="78158" checksum="0DDE06EA991989CE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6S2</accession>
    <name>A0AAD9D6S2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sel1 repeat family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6S2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="157" mass="17455" checksum="22F6E353A490FF54" modified="2024-05-29" version="1">MGTEHFVKEDYVGALFEYWTKAAESGDALAHYELSCFHQNGKGVEKNEKKRLYHLVEAAIGGHPGARFQLAGYEGKNSRFDRMVKHFIIAANLGHDGSIQMLKGCYKHGLVSKEDFAAALRAHQAAVDATKSPQRDVAEAFAEKFRSYQQQTFGGNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D769</accession>
    <name>A0AAD9D769_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014049</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D769"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="22"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="203" mass="22689" checksum="686036C565CFBA29" modified="2024-05-29" version="1">MPRSMTKKPPQLLPNATSTVTDLSTDVIEMIFGNLPQIDIMRARVCRKWRQAARNAIAPLTEFKVDTARQYNAMEAMVIPFLIHSRLCSKVSITGKNPSTMERTHEDEAECTANYTTHDIGIVSNFTMLIHLEILGATLSGRYPFLFSIASRLDRLKMINCGGLLLLWHLDDLATSSALKELHCEGTPVKGNIKCLKESSKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7Y6</accession>
    <name>A0AAD9D7Y6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_013184</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7Y6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1736048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="119" mass="13793" checksum="1E96B2003DBA99EF" modified="2024-05-29" version="1">MTLLGRGVRHVVITDDDEVLYVVKYDDAVLGQINGFIKHSSMDVTMFPPDEVTEAIRRSFAADERDPLPPPREQCYLAESSFNALKELGLPIEETDFLNEDELRYGYKNSYFSCDWRFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8W3</accession>
    <name>A0AAD9D8W3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Serine/threonine-protein kinase</fullName>
            <ecNumber evidence="11">2.7.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_011981</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="11"/>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8W3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050205">
        <property type="entry name" value="CDPK_Ser/Thr_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24349">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="1"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="219"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="319"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="355"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1737114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="392" mass="44624" checksum="12142C575956C6EC" modified="2024-05-29" version="1">MYDVFEDDDEYWLSMELIEGGEVFEHLISHGAYSEIVAATFLRQFAEALAFMHSAGVVHADLKPENLMLSCWNEEEAEVKLVDFGCALIVSEDGIDEKLCPSTPAYDPPEKIINDSAPNFQSDVWAAGCILYIILTGTHPFDKNNDVTDEEIKDKLTSIGTGKTDLSREANDCREIQEEHMGARSHGIVGILDKSHKRLELYWQRELRKSIFKKFGDGLDEEKLREVFQQIDSDGNGKLDLEELTKVLQSVGAKKKDIHNIFNAANLEKKDGISFEEFRSVVLSNEPSELKDRQHYQKAFRTIMRKQLELQQKGKMTLSWRAAARRLFASMDLDHNGTLDCYELRTLLRKLGVEEKDISFLVASVDLNKDGSISFDEFSKVIFRAQKGRIIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DA81</accession>
    <name>A0AAD9DA81_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DA81"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1739872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="245" mass="27687" checksum="A1B8E13E2D93631F" modified="2024-05-29" version="1">MEANDETFVYTGARGQQIPEQVARVIIDKSCKIIPDRAFSGREYLEEVHLHEEVEEIGYGAFYGCKRLRRINFPANLSVIGWMAFSFCKDLTDIELPKDLKVIGEEAFRLCNSLTVVKLPENLDVVGKQAFLGCTGLKEVELPSGPKRVGIGYRAFGSCTSLMRISIPLNVQLLSTNHQIFDHCDLLNSINITGGVHDVVSSLTLEKWRNEINAEMRRINSILPSIKRGPKTTRMQDWMESVHFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAR0</accession>
    <name>A0AAD9DAR0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carbohydrate-binding family 9-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAR0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09620">
        <property type="entry name" value="CBM9_like_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010502">
        <property type="entry name" value="Carb-bd_dom_fam9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35532:SF5">
        <property type="entry name" value="CARBOHYDRATE-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35532">
        <property type="entry name" value="SIMILAR TO POLYHYDROXYALKANOATE DEPOLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06452">
        <property type="entry name" value="CBM9_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carbohydrate-binding" evidence="1">
        <location>
            <begin position="34"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="276" mass="31567" checksum="FB9667FF8219EF39" modified="2024-05-29" version="1">MLLSPSPYAAIYPQQYIAYRSDVTSTAEEPAITIDGNLDKPFWNDIPWTEDFVDISTNTPPSQRTMVKMRWDDHFLFVGARMEETDVWATLTEENSVIFQDNDFEIFVDCDGSNHNYKEFEINALGTTWTLLLDKPYDDGGGENSKRVDPVNGYDMSPFIRSATKVYPNDAINRPDVRNTHWTAEVALPISKLMERNELAKRPSDGHQWRINFSRVQWGVKVNEKGEYEKKPCCQSCAVPGTAAEDNWTWSPQGKVQCIFLNDGVFAIQFVDKSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBH0</accession>
    <name>A0AAD9DBH0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kinesin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009437</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBH0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24115">
        <property type="entry name" value="KINESIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="2">
        <location>
            <begin position="18"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="79"/>
            <end position="86"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="528" mass="58289" checksum="03F2AD8F463FA6A0" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DC73</accession>
    <name>A0AAD9DC73_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">IPT/TIG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006746</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DC73"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00102">
        <property type="entry name" value="IPT"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="CDD" id="cd00603">
        <property type="entry name" value="IPT_PCSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052387">
        <property type="entry name" value="Fibrocystin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002909">
        <property type="entry name" value="IPT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46769:SF2">
        <property type="entry name" value="FIBROCYSTIN-L ISOFORM 2 PRECURSOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46769">
        <property type="entry name" value="POLYCYSTIC KIDNEY AND HEPATIC DISEASE 1 (AUTOSOMAL RECESSIVE)-LIKE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01833">
        <property type="entry name" value="TIG"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00429">
        <property type="entry name" value="IPT"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="IPT/TIG" evidence="2">
        <location>
            <begin position="38"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="IPT/TIG" evidence="2">
        <location>
            <begin position="124"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="IPT/TIG" evidence="2">
        <location>
            <begin position="214"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="IPT/TIG" evidence="2">
        <location>
            <begin position="301"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="IPT/TIG" evidence="2">
        <location>
            <begin position="488"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="domain" description="IPT/TIG" evidence="2">
        <location>
            <begin position="580"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="domain" description="IPT/TIG" evidence="2">
        <location>
            <begin position="774"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="domain" description="IPT/TIG" evidence="2">
        <location>
            <begin position="965"/>
            <end position="1046"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1046" mass="111736" checksum="BD8C7ED3696C8A9F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DC82</accession>
    <name>A0AAD9DC82_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Bile acid:sodium symporter family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_006776</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DC82"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004710">
        <property type="entry name" value="Bilac:Na_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10361:SF28">
        <property type="entry name" value="P3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10361">
        <property type="entry name" value="SODIUM-BILE ACID COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042236463" evidence="7">
        <location>
            <begin position="22"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="324"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1742211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="432" mass="45311" checksum="B2B0584E30DAD65C" modified="2024-05-29" version="1">MRMYYSFIASSLLLAAGVVDAFTPPSSSSSLRHITGGCHHHLSSPQYYSATIHNKSTPRSWRSTNKLLQLSNNNNDDDQTKQPSSTSKIDQILSQLTSLFPLFVLGASITGSIIPSTLNWVNNGNIISAMLAGVMLGTGMTLEKSDFGTILTNKQQRKSIPIGVLCQFVLMPLSASIIGRALLLPYHDPTTMAHVGKHLFLGLVLVGCSPGGTASNLVSLIAGADVALSVLLTTCSTILASVVTPLLTKFIVGSAIPVSGKALMLATAKVVLLPVALGVFLNEYFPKLCQQVSRWTPFASVVLVSLICGGVVSNNAAMWTTGSAAAVAGGGALSLPMLILLAVCLTHTLGFTAGYLVPKKVFGLPERTARTVSIETGMQNSALAVVLAKSIGADPLSYLPGALSATAHSVIGSGLAAFWRLMDSRKKTDDNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCP2</accession>
    <name>A0AAD9DCP2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyltransferase (GlcNAc)</fullName>
            <ecNumber evidence="1">2.4.1.229</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_007137</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.229" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCP2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033830">
        <property type="term" value="F:Skp1-protein-hydroxyproline N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021067">
        <property type="entry name" value="Glycosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34496">
        <property type="entry name" value="GLCNAC TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34496:SF6">
        <property type="entry name" value="GLYCOSYLTRANSFERASE 2-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11397">
        <property type="entry name" value="GlcNAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1742572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="358" mass="40129" checksum="8E9D5FD1DF709586" modified="2024-05-29" version="1">MTTLGDYGEIFMGNPKNLERAGYKDKGGNIAYDPEFECTGGSSDPNDRQCPYETKESDAMGLETTGWDGRLMHLNMPSFRDPLCPRTLKYLFTKAKRPNDIRVRVLQQNMDVDDDCLETYCKMMAQLREETGGGDTSKGGPAGEDCPHRDQIFVHPISAKDAAGPTYARGLIGQDMHAAYAKNGISPQDFCMSTDSHMDFEPEWDEKMVNMWDQAKNEYAVLSTYVANIDQLGQNLNGVHEVPHLCMITFTSQVRTTATKCARNLVKPKLTNAVWGAGLSFSKCHAELKVPVDPHTPGIFDGEEFNRAARFFTYGYDVYTPNRVYVLHDYHGSQHNPKTSSWGTGNLGKRTYKMHTTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DD34</accession>
    <name>A0AAD9DD34_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005807</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DD34"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="623" mass="69995" checksum="93F2B3C93A7278A3" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDQ2</accession>
    <name>A0AAD9DDQ2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005458</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDQ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="86"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="168" mass="18822" checksum="42D94BA1B80A1A9E" modified="2024-05-29" version="1">MAVDHLMQNYDEQGHYIMKNNNNLVQNEPEDYFIALYNGTDTLCDLSMARQNGLAGLVRTQLRRQPPLIVGPSSDGTPSILVLPPTVTIPSSHLYVANMRVGDTMQRRGIGMTLLSSIKDYVDTLGEDRNIPLVLSVDSDNLGAIQLYEKFGFEYLERNSDWGTMILI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDY0</accession>
    <name>A0AAD9DDY0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007079</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDY0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057491">
        <property type="entry name" value="DiatomPyrShell"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25192">
        <property type="entry name" value="DiatomPyrShell"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042186159" evidence="1">
        <location>
            <begin position="24"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="305" mass="33081" checksum="4DC3BAD4617789EB" modified="2024-05-29" version="1">MAAVTTVAMWKAIALIGLAVAEAFVVVSSSPRERSVSTQLASEYGASARTRTQDDYIDINRESGGPIVRYDGPTIRPLSNYNAGDCAGWISENLVVCQSQVDAVQVLFKSEGRPIDADIDLWNGPDNTPHKMRVYVEDGARRTFSAIIGTPRGPNSIAVRNIGQLEFPLDAVVRPDMQGGLAASIASVVSKAEVIQGGSVRTWSFNPVVQSVAVIIKTDGRPLNSRIELLMGPNNSKQVVEIYTEDGVERPFFAIVETSEAVGSVIRIKNTAPLEFPVYASVAPYTLGEYDFVGDSYSFNEWPMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DED0</accession>
    <name>A0AAD9DED0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">60S ribosomal protein L37a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_005114</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DED0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011331">
        <property type="entry name" value="Ribosomal_eL37/eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002674">
        <property type="entry name" value="Ribosomal_eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050522">
        <property type="entry name" value="Ribosomal_protein_eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48129">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L37A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48129:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01780">
        <property type="entry name" value="Ribosomal_L37ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="15"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="33"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1744581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="94" mass="10231" checksum="9A06513BD3C9FCEE" modified="2024-05-29" version="1">MSIIYHFTHLIPLSPSNSTPSQHHSISTLIQHGKAHKKGRNHRKDSVKRTVVGIWSCGSCKKTVAGGAYSLSTASAVTVRSTIARLRKIQNEAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DF93</accession>
    <name>A0AAD9DF93_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">CLC voltage-gated chloride channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_006124</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DF93"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015108">
        <property type="term" value="F:chloride transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3080.10">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051280">
        <property type="entry name" value="Cl-channel/antiporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="ClC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11689">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11689:SF136">
        <property type="entry name" value="H(+)_CL(-) EXCHANGE TRANSPORTER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1743503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="241" mass="26775" checksum="E8FDF77E708BE91D" modified="2024-05-29" version="1">MEEGSSFWSIQLMWKCVNATATTLLAWFFLESAKKGFGPQTIPLKFALQNGDGETSFIFIAVHYWEYFLVAAIGIAAGLIGCAFVEINIRLTKLRRRLNFSKPLQLLEVIFFTVLMASLTWNLPLAYTVCKKDSFPDMEFIQFNCPDGEYNELATLLLATPSTYGLKHTFHAEAHAFTIQSLVIAGCVYLFVLLFLFGAKLVMGIFIPLLYAGSCFGRAIALSLKLDPFMYAVVGASALLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG94</accession>
    <name>A0AAD9DG94_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_003228</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DG94"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="180" mass="18890" checksum="7FB427DBBFC3A455" modified="2024-05-29" version="1">MANGNGTVRRAKADKCNSFSETVSDLLEQLEDIDIGTGAEAGSSAIEAPAEAKDMGIGGTKKAAQFLLHATKAAVASVVESGIIGDNLTIYTIKATGMVALTDETKEEKALLVASLLKMASAHKYPAKIGIIELFQANLGWMTKNLMISGCLLGDTCLLIRYNVRCVAGQRVGICVVILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGH3</accession>
    <name>A0AAD9DGH3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ethanolamine-phosphate cytidylyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">CTP:phosphoethanolamine cytidylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_004054</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from ethanolamine: step 2/3.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.14" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGH3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004306">
        <property type="term" value="F:ethanolamine-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044608">
        <property type="entry name" value="Ect1/PCYT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45780">
        <property type="entry name" value="ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45780:SF1">
        <property type="entry name" value="ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="275"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="305"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="365"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Cytidyltransferase-like" evidence="6">
        <location>
            <begin position="410"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1744763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="559" mass="62782" checksum="42F91859C1400E53" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DH09</accession>
    <name>A0AAD9DH09_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Dihydroxyacetone kinase</fullName>
            <ecNumber evidence="8">2.7.1.29</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_001439</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the dihydroxyacetone kinase (DAK) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.29" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DH09"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004371">
        <property type="term" value="F:glycerone kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1180.20:FF:000001">
        <property type="entry name" value="Dihydroxyacetone kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10440:FF:000001">
        <property type="entry name" value="Dihydroxyacetone kinase, DhaK subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.340:FF:000002">
        <property type="entry name" value="Dihydroxyacetone kinase, L subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10440">
        <property type="entry name" value="Dihydroxyacetone kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1180.20">
        <property type="entry name" value="Dihydroxyacetone kinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004006">
        <property type="entry name" value="DhaK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004007">
        <property type="entry name" value="DhaL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036117">
        <property type="entry name" value="DhaL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050861">
        <property type="entry name" value="Dihydroxyacetone_Kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28629">
        <property type="entry name" value="TRIOKINASE/FMN CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28629:SF4">
        <property type="entry name" value="TRIOKINASE_FMN CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02733">
        <property type="entry name" value="Dak1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02734">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01120">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82549">
        <property type="entry name" value="DAK1/DegV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101473">
        <property type="entry name" value="DhaL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51481">
        <property type="entry name" value="DHAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51480">
        <property type="entry name" value="DHAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DhaK" evidence="7">
        <location>
            <begin position="9"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="DhaL" evidence="6">
        <location>
            <begin position="406"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1747476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="609" mass="62960" checksum="BE4C99FD1DE3AB1E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHC0</accession>
    <name>A0AAD9DHC0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ferredoxin--NADP reductase</fullName>
            <ecNumber evidence="4">1.18.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_003512</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.18.1.2" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHC0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004324">
        <property type="term" value="F:ferredoxin-NADP+ reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009577">
        <property type="entry name" value="Sm_multidrug_ex"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36007">
        <property type="entry name" value="TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36007:SF2">
        <property type="entry name" value="TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06695">
        <property type="entry name" value="Sm_multidrug_ex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041948096" evidence="3">
        <location>
            <begin position="25"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="268"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="428"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="510"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="312"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1745588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="573" mass="61004" checksum="F8F48CF10555B502" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DI99</accession>
    <name>A0AAD9DI99_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Small EDRK-rich factor-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000151</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DI99"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007513">
        <property type="entry name" value="SERF-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04419">
        <property type="entry name" value="SERF-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small EDRK-rich factor-like N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="98" mass="10775" checksum="F7E9CEAD605862C5" modified="2024-05-29" version="1">MARGDQRERDRAKKLARLQKEQKGGPKEGNPESRNLNDSAALAAKVAKKAEMKKKQEEEEQRNAANKPVVVKSKAKKKKEPAGLDDLLSAGLAKGKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIG7</accession>
    <name>A0AAD9DIG7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dehydrogenase</fullName>
            <ecNumber evidence="2">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIG7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840:SF3">
        <property type="entry name" value="BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G10240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="374" mass="40384" checksum="ECF8837135FEC104" modified="2024-05-29" version="1">MVVTPSPSQAEVILVGCGCPLRGMGWYHAVQMLGNECPSAKLCHIVEPWFLGPGATGPGGSEFAEFKSKAEADHQVGFYKSLADVPPVADGVKRLALISGRTMDNPRLLGESIAAGCTVIYLEKPGAPTVKELEVMKREAADANVKICMGYNKNVCKYVRNAREFAAANEGSHVTFVSNNTYENNASSLGECFERNAEGMLKNMAIHELALLASFYDVTVDNIESVVVDKDFSSMQTLPGPSGKEFTDFDKVKFTIKTKTGKAVSVQADRCGGDTSFAMVSDADGKEMFRHCMPDEEDEANVSVLEAKYPGAMPYFFSQDPDYITVKERVAKMCVTGEEALDIATIDIAIAALSVGEYLTPLMQKELSGTVASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIL3</accession>
    <name>A0AAD9DIL3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_001170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIL3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF109">
        <property type="entry name" value="RIBOSOMAL LYSINE N-METHYLTRANSFERASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1749231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="254" mass="28630" checksum="3A4DAFAB95C25425" modified="2024-05-29" version="1">MAEMGDNSEGDKQVFLSIDETPIYFREDWNTGIGGGLWSTGLAIAKYFEHHYSDVSDNLNRLAEMKRKRGENDGISAIELGSGNGFLSACLLALAQTTSLSLKNVVVTDMEDHLILMEKTIRTNPHVWDELIVTKEGSSSTYHGSPSNRKERPASSVTVAEYKWGVDDFNQKYDFIFGSDLAYRDYLHDPLISSLLQLSHQHTICLIGVTMSDTRPVFFDKLTEAGFLYQRLADHYLEGHFRGGTFGIFVIMRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DK92</accession>
    <name>A0AAD9DK92_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">AAA ATPase, CDC48 subfamily</fullName>
            <ecNumber evidence="6">3.6.4.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_000799</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.6" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034098">
        <property type="term" value="C:VCP-NPL4-UFD1 AAA ATPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097352">
        <property type="term" value="P:autophagosome maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051228">
        <property type="term" value="P:mitotic spindle disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030970">
        <property type="term" value="P:retrograde protein transport, ER to cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000018">
        <property type="entry name" value="Cell division control 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000012">
        <property type="entry name" value="Transitional endoplasmic reticulum ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.20.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.80">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003338">
        <property type="entry name" value="CDC4_N-term_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003123">
        <property type="entry name" value="VPS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037191">
        <property type="entry name" value="VPS9_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF171">
        <property type="entry name" value="NUCLEAR VALOSIN-CONTAINING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02204">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01073">
        <property type="entry name" value="CDC48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00167">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="ADC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109993">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51205">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="VPS9" evidence="5">
        <location>
            <begin position="371"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="119"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="236"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="583"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1360"/>
            <end position="1389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="119"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="594"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1371"/>
            <end position="1389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1748860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1389" mass="150103" checksum="8A086F74CD6FA5A5" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S1CUK3</accession>
    <name>A0A7S1CUK3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP synthase subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">QTG54_012949</name>
        <name evidence="17" type="ORF">SMAR1040_LOCUS877</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">FE60</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <dbReference type="EMBL" id="HBFU01001327">
        <property type="protein sequence ID" value="CAD8926930.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S1CUK3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18113">
        <property type="entry name" value="ATP-synt_F1_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18116">
        <property type="entry name" value="ATP-synt_F1_alpha_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01132">
        <property type="entry name" value="F1-ATPase_alpha_CD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.150.20:FF:000001">
        <property type="entry name" value="ATP synthase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.20:FF:000001">
        <property type="entry name" value="ATP synthase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000002">
        <property type="entry name" value="ATP synthase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.150.20">
        <property type="entry name" value="ATP synthase alpha/beta chain, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01346">
        <property type="entry name" value="ATP_synth_alpha_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000793">
        <property type="entry name" value="ATP_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038376">
        <property type="entry name" value="ATP_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033732">
        <property type="entry name" value="ATP_synth_F1_a_nt-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005294">
        <property type="entry name" value="ATP_synth_F1_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00962">
        <property type="entry name" value="atpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009884">
        <property type="entry name" value="PRK13343.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48082">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48082:SF2">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00306">
        <property type="entry name" value="ATP-synt_ab_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039088">
        <property type="entry name" value="F_ATPase_subunit_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47917">
        <property type="entry name" value="C-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="N-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="6 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 13" id="KW-0139">CF(1)</keyword>
    <keyword evidence="5 12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit N-terminal" evidence="16">
        <location>
            <begin position="60"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding" evidence="14">
        <location>
            <begin position="183"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="ATP synthase alpha subunit C-terminal" evidence="15">
        <location>
            <begin position="407"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="CAD8926930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1736349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="539" mass="57478" checksum="C4F453965328A810" modified="2021-06-02" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S1CV35</accession>
    <name>A0A7S1CV35_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_003403</name>
        <name evidence="3" type="ORF">SMAR1040_LOCUS1375</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">FE60</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="HBFU01002059">
        <property type="protein sequence ID" value="CAD8927428.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S1CV35"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042409305" evidence="2">
        <location>
            <begin position="17"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CAD8927428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1745479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="90" mass="9178" checksum="4FFD22FB80B133AE" modified="2021-06-02" version="1">MRSFFLFSLLVAAASAFVAPANQAVAFNRASTVEAPKMMIDGSVLDSAVQTANLIATSSDANGGAFFPVAGIVSLAGLILYLAPPLVDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1GY33</accession>
    <name>A0A8K1GY33_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L31</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpl31</name>
        <name evidence="5" type="ORF">QTG54_017158</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="6"/>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2021" name="Front. Plant Sci." volume="0" first="0" last="0">
            <title>Chloroplast Genomes for Five Skeletonema Species: Comparative and Phylogenetic Analysis.</title>
            <authorList>
                <person name="Liu S."/>
                <person name="Xu Q."/>
                <person name="Liu K."/>
                <person name="Zhao Y."/>
                <person name="Chen N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CNS00100</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MW679506">
        <property type="protein sequence ID" value="UAM91366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_010200871.1">
        <property type="nucleotide sequence ID" value="NC_058701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1GY33"/>
    <dbReference type="GeneID" id="68637990"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.30">
        <property type="entry name" value="Ribosomal protein L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="Ribosomal_bL28/bL31-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002150">
        <property type="entry name" value="Ribosomal_bL31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042105">
        <property type="entry name" value="Ribosomal_bL31_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00105">
        <property type="entry name" value="L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001809">
        <property type="entry name" value="PRK00528.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33280">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L31, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33280:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL31C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01197">
        <property type="entry name" value="Ribosomal_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01249">
        <property type="entry name" value="RIBOSOMALL31"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="L28p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01143">
        <property type="entry name" value="RIBOSOMAL_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1732115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UAM91366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="72" mass="8299" checksum="020194051006BEBE" modified="2022-08-03" version="1">MPKSEIHPNWFPDSEVKCEGKTLCVIGSTKPQLQVDVWLGNHPFYTDSQTLIDSEGRVERFMKKYGLQTKDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRU7</accession>
    <name>A0AAD8XRU7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_017075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000078">
        <property type="protein sequence ID" value="KAK1732250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRU7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="313" mass="34573" checksum="C8C3C8F47B4F935A" modified="2024-05-29" version="1">MALTDTKNYRRFIPSTGGVGLREDANRSSSSADGDGDLKDAMDEEDSRCICSKSEKGISTDRQDHNTTDAIIRTLQRTSSNSNSSLQMSSQQQHRQEEDTSCSANSITPTFSFSSPSGKEIIANKAKYKHSNSGSSPMTAITRTSLTTASSSTTSSGSSNVGSRHNNSYPDEILARNTIISFEQKSDKDVKSASSCPSIPFFDYLEEQVSKLIEKNESAPKCCVATILPRRNSITHRPELSPISSQSVAVAEAKNIRRLRREVLGLYRTLDTLKKDSREWMLLKSKLDAAREELDAVLEDQQLVRSIETVKTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRX6</accession>
    <name>A0AAD8XRX6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">YqeH family GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_016913</name>
        <name evidence="5" type="ORF">QTG54_016914</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000068">
        <property type="protein sequence ID" value="KAK1732378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000068">
        <property type="protein sequence ID" value="KAK1732379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRX6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01855">
        <property type="entry name" value="YqeH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050896">
        <property type="entry name" value="Mito_lipid_metab_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048422">
        <property type="entry name" value="NOA1/YqeH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46434">
        <property type="entry name" value="GENETIC INTERACTOR OF PROHIBITINS 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46434:SF1">
        <property type="entry name" value="GENETIC INTERACTOR OF PROHIBITINS 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21516">
        <property type="entry name" value="YqeH-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="2">
        <location>
            <begin position="306"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="NOA1/YqeH-like C-terminal" evidence="3">
        <location>
            <begin position="436"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="552"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="553"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1732378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1732379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="572" mass="63345" checksum="455958DB2FA90AEB" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSJ4</accession>
    <name>A0AAD8XSJ4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RxLR effector protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016194</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000054">
        <property type="protein sequence ID" value="KAK1733056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSJ4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041898541" description="RxLR effector protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="120" mass="13235" checksum="50548F83DD0E0A51" modified="2024-05-29" version="1">MKSFFLITFALLATAASISAFAPNYSRQTIIASRIRLFMARSKPAKSQEEDVELTRAIIMKHIGSVEDFVVDDGTVEEVEASSEEADDESNESKSMKDKLKGTGRKIKDKLKSTIQKGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTL8</accession>
    <name>A0AAD8XTL8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">guanylate cyclase</fullName>
            <ecNumber evidence="2">4.6.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">QTG54_016107</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.2" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000052">
        <property type="protein sequence ID" value="KAK1733250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004383">
        <property type="term" value="F:guanylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001653">
        <property type="term" value="F:peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007168">
        <property type="term" value="P:receptor guanylyl cyclase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001828">
        <property type="entry name" value="ANF_lig-bd_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050401">
        <property type="entry name" value="Cyclic_nucleotide_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920:SF335">
        <property type="entry name" value="GUANYLATE CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920">
        <property type="entry name" value="GUANYLYL CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01094">
        <property type="entry name" value="ANF_receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0141">cGMP biosynthesis</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="617"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="662"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="15">
        <location>
            <begin position="1090"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="27"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="694"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="757"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="767"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="689"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1733250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1287" mass="139132" checksum="DEEB53BB7AEE79C2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XU30</accession>
    <name>A0AAD8XU30_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sulfotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000045">
        <property type="protein sequence ID" value="KAK1733742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XU30"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="453" mass="51743" checksum="356B48C27F5A4D02" modified="2024-05-29" version="1">MTFARRLGHPSLPSTYADDDIAAVTITNSNKKDDHKHQNHSLKFLIFGQTTSCTSALILMIGATLMLMTISLIQKNFHPLFELPYQSQNLKLTYTAELAAKAVEPTVWTCGETDRHKQTAVVDPITNQRPFFAFVHVYKTGGTTVREFFREYAAVCKKSLALVAKCGLGKDLEDCNFLSCVNAPQSIERVNSTILHDNYDILGGHFNFGMADDIFSNATATPNYGNGAPQVRHMTFLRQPITRFVSHILYQQKQGNVDKTDTVEETVEDIKKRIRSSREKGEYVSSSIYPFYNNLLTLEQHAMKYDQEQTTQEQQELVKVQLSIDNLLRYNAIVGMTETFSQSIQIFEHAMGQIVNSTRKEEEVQEMFSRYIGEKESKNGSKRNDISTGSVLKELNKDDEFMAIFREFVKYEQMIVDFAMDMHQKQYKAVKKGHFERYTLDSSDMLYLDSVGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XU45</accession>
    <name>A0AAD8XU45_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_015543</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000045">
        <property type="protein sequence ID" value="KAK1733688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XU45"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF69">
        <property type="entry name" value="FERRIC REDUCTION OXIDASE 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="3">
        <location>
            <begin position="131"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="589"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1733688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="691" mass="77925" checksum="12FAE09405C5C7CF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XU73</accession>
    <name>A0AAD8XU73_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ion transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_015499</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000044">
        <property type="protein sequence ID" value="KAK1733802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XU73"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001518">
        <property type="term" value="C:voltage-gated sodium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005248">
        <property type="term" value="F:voltage-gated sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043203">
        <property type="entry name" value="VGCC_Ca_Na"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10037:SF62">
        <property type="entry name" value="SODIUM CHANNEL PROTEIN 60E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10037">
        <property type="entry name" value="VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="7">
        <location>
            <begin position="20"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1733802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="256" mass="29049" checksum="EFF2E7DC4421F361" modified="2024-05-29" version="1">MVPLQGWISCLRSTNCGHELGVGGTQVIRAFRIFRALRLITRIETMRNLVMALFSVIPKMTAIALLLMLIFFIFSVMMTTLFKNMYPETLTQPYFESLFYSLFTLFQMMTLDEWADILGQVQEVYPWAWAPFIIFIVITGFVVVNLIIAVICDAVHVLGNENKAGLYGYDSEEGSLLSKTKKATDKPIHPPDQVQVAPSSQSTATQRLEELQHQLDEMVKAQDQMRRTIEVLSSRLTFSHDVHDGEVSQCEGDDDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUR1</accession>
    <name>A0AAD8XUR1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015330</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1734072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUR1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="81" mass="9395" checksum="78972BFDFC8191D8" modified="2024-05-29" version="1">MRREGDSDDESDDEDEIIFTTDYELGTDDLGWLGFYIGRSEHLIKLNIFDLPYHPAELHDEQMDALTRGISRNRSIVGTYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVV1</accession>
    <name>A0AAD8XVV1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_014787</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000038">
        <property type="protein sequence ID" value="KAK1734539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVV1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006571">
        <property type="entry name" value="TLDc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14499:SF136">
        <property type="entry name" value="GH08630P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14499">
        <property type="entry name" value="POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00536">
        <property type="entry name" value="SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07534">
        <property type="entry name" value="TLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00584">
        <property type="entry name" value="TLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51886">
        <property type="entry name" value="TLDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="3">
        <location>
            <begin position="61"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="TLDc" evidence="5">
        <location>
            <begin position="167"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="SAM" evidence="4">
        <location>
            <begin position="457"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="364"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1734539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="589" mass="66445" checksum="6D667FC1A9213D15" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW12</accession>
    <name>A0AAD8XW12_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XW12"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="206" mass="21499" checksum="7BA613BF3A6F8CA8" modified="2024-05-29" version="1">MSDAESTPTMSIKDRIAALQKGKGGESAIPVGPPPTKPKKSNALAGRIAALQLQSAAEKESSDKHLDNHPSNSDRNNTGSTKVGKLKLPPGGVPIIMPGAGPPPSLLKKQKEREERKQKMIEDAQKEEAESAENTSTTSSVGKLKLPPGAIKLIVPGCPPPAMMAKADGGAVVEASGEKTTAATSDDALMSRPTMPKRRPRNRGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW59</accession>
    <name>A0AAD8XW59_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 1B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_014488</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SUI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XW59"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11566">
        <property type="entry name" value="eIF1_SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.780.10">
        <property type="entry name" value="SUI1-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001950">
        <property type="entry name" value="SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036877">
        <property type="entry name" value="SUI1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005874">
        <property type="entry name" value="SUI1_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10388">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01253">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004499">
        <property type="entry name" value="SUI1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55159">
        <property type="entry name" value="eIF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50296">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SUI1" evidence="3">
        <location>
            <begin position="27"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1734615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="109" mass="12071" checksum="D09DDEFB7FCC416C" modified="2024-05-29" version="1">MADLAFNNFDAFKDAADEPGASQGEKVHVRVQQRNGRKCITTIAGLADDLDIKRICKAFKKNFSCNGAVQKDEDDSEVIQLSGDQRTNVKEFLVDQEICHSDAIVLHGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWX0</accession>
    <name>A0AAD8XWX0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014043</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWX0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041914906" evidence="2">
        <location>
            <begin position="18"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="140" mass="14325" checksum="0DE9532D438B974E" modified="2024-05-29" version="1">MRTSALIFAAALATASAQDAYNHQLRGDRFLSVSTKAEKATSVATKAAKSSTKSSKTADAKAEKVSSAKAAKEASMPKEAKAEKEPETKSPTTSVAKAAKVMSVEAKAVKSEDDSISSSKAAKAVDAKAEKASSVATKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXX3</accession>
    <name>A0AAD8XXX3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000031">
        <property type="protein sequence ID" value="KAK1735924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXX3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="273" mass="29971" checksum="865F09BB46DC3156" modified="2024-05-29" version="1">MHHTLPTTEEARHAAFDLRRRMIESGRIDVDELKLQLDHDDNEDILHALNPSLAIERLYERRGKMFGVLVCQVPDNSLYSDSSNLTSGDTVILKAYAGKLGGSWNLPGWSPIIGQVPESLPVFCRLRDEVTELFDRIDTTKSNASPEDEKKKGSKENKVKHLTKKRARLATLALDEVRRHQLVTNFRGEALRPLTTVYTRGPTKVPGGTGDCAAPKLLAEAARLGLRPTGIAEIFVGATGGMSTGKGDGELYDACADRCEKIAGFMLCGLDDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYK7</accession>
    <name>A0AAD8XYK7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013248</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYK7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="366" mass="39480" checksum="DB7102E4F8951345" modified="2024-05-29" version="1">MPLTSIRALPANPNDSCSNDSENMNNGGPCRLSFKLDLSWSVDTEPSAESAVSGDVGSISGYNSQNGYMVEEQWISCVSDSELNLNGGDYLVEEFNFIYEIYTPVDDSTDEVLDTLANFERNLSLGVSEALGLVHCAGSETQLSVARSAGPWLRRSLTSLKNNHRFLDDDATSDILAVSMMPKDDIDYASACTSPVQTDEPAQCSHVVGGMTAWINKADGASAIPNEDVFLNAVESYIKDDNSKYLGNGLVHVEYIGELDSTTYTTTLGASDVSSGPSSTGSILGLALGGAFFAVAGVGGAWFYRKKRNKNQYELEEKSEVIVKDDDIQLQDTEEITSFDDPPSVETDSSDARTADYQLKRVGPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYP7</accession>
    <name>A0AAD8XYP7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_013594</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYP7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1735888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="402" mass="45119" checksum="44DFDE9590564B2C" modified="2024-05-29" version="1">MVSTRNAKKAKTEADAGVSNGARGEDVGLLESIYWDHVRPFTPVKERAVVSKRCSTRFYAGKRVELDETYLKQYERRGRIKLKNVDGRWVDVDGDDTVVYRNLPIARGEPGTNNFRIEFGEEVSFHTGSDDSLGHSDVALEMLLAARKAWDNHLSKFQSPSQRLRICLELLHTDEHDGACPFLFIGKGGIRDVVRFHASVNLASLNGPSHGQKSFPNTQLGYWVACYLSDIMMGVYDGASYSSTWKYGEIVSELIDAGADVSPFFEPLDAYPHTFSALSVMGGHHNFYERGMSMHQVLAAHAEWHRQQEEGPVAPWHQLSGQPGRTIGSLLDSLGRKSNIKLRFNAGDRVECNMGEEDGWMPGTIKKQWYYGFPYEIDVDNLNGSSVWAPFDGDECIRTLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZE6</accession>
    <name>A0AAD8XZE6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vms1-associating treble clef domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZE6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="273" mass="30958" checksum="CE1B3D1D3014CBE5" modified="2024-05-29" version="1">MGLGSTSNQEGLLIIDDDEAAHEAADVAAWREVQDEFPTLGETRTSTSLPTSCDQNDDMPCQILATVRHTAELVIKEEKEKEEAAEKARQRYFLEALERKRRRIDARRKAKGDTAKVLVDDKKAEAVKLSAREEIDRWLSQKWNEWETHSLETKTKQKTNDCAVSTADEPCEMESSKKSSPTLQKNELTEEEKAAKAAAKKKAKRQKAKERAKEKKQIEKLEREKKERAMALRKEKESSSIKCAHCGEGVLGFGYDKFDKKYCSTKCARSGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZJ4</accession>
    <name>A0AAD8XZJ4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZJ4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1310.10">
        <property type="entry name" value="Nucleoid-associated protein YbaB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036894">
        <property type="entry name" value="YbaB-like_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041937545" evidence="1">
        <location>
            <begin position="21"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="179" mass="19014" checksum="C5B31F09DB19F5AC" modified="2024-05-29" version="1">MKTSALTIAACAAAISQTVAFTTSPSLSITRTITASPQPASSAALNMFSGGALDIEEEEDDEKRTQMEQYAKAMGMSVEEYQLGMNARVKMETAINDLRVIGGDAANGVTVERDGNMPPRHLVVTVTDDGKAKGKEALEGLIVEALKSAADKSKVGRDQAQKDMMTYISDSMKKMGMNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZL4</accession>
    <name>A0AAD8XZL4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012942</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZL4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1736342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="66" mass="7785" checksum="23C7DA245968AE2A" modified="2024-05-29" version="1">MFARSAVRMARYDVSPHLSKWWKGVRPDDGQVTRHLSPFEQQIVMPWLKTFPKRAYAKFSDSGPYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZT2</accession>
    <name>A0AAD8XZT2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012815</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZT2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="305" mass="33505" checksum="1761555795498694" modified="2024-05-29" version="1">MPNVPKFLRRGGNSSSSQDDDSASASDYHRYSSDQAAENDVQRTAVNRALNTLNSGNDDTVENTRAPIRVSFVPVTPQSDELGKEVESNATGHEVKQSHQKHVHEAENNTYEKADDDSSGAWWNLLSNKGSFDTTSVAVSPMKEPLGAAASNYIKKEKMLRKKAFNRAALGGSIQFDHTFSDESSPTSLPYRHQSSSWGAGLPSKQQDEDIPIEWTRQDSSYGAAISAFGWLPKRIRKLLESLFVVLAIAILVYVVVKIGAEISHTHSSASSGGDFDLDDDDHYIAHNNNNGGEDDVGDERFRFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZU0</accession>
    <name>A0AAD8XZU0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UMP-CMP kinase</fullName>
            <ecNumber evidence="5">2.7.4.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_012779</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZU0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:AMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1736757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="253" mass="28421" checksum="E704F62175A2485F" modified="2024-05-29" version="1">MAAQAKTTLISLVGKPGSGKGTYGALLASRYRNLTFLSVGDVLRDSAKRNETLRRVLTSGKLVDDTIVNEAVIESLQEENLQQLKAQHSIDSDAKVFNDGGEHIILDGFPRTDAQTKLLSKWPSSLEPALAIYFDVPDDIVITKLLGRRKCTICGGNFNINGVEQDGWDMPPLLPKNGCKEKCDWDIHWEKRDDDTADIIKERMQVFRQETEPVLESWSDSNRLVTFVPYKGVKEMDRLAGVLENYFHKHSLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y112</accession>
    <name>A0AAD8Y112_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y112"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1736966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="276" mass="31844" checksum="31B984C863B7D8DD" modified="2024-05-29" version="1">MTVAEFEKQEADDAAYVRRERMRHQYEGTVEHVMLGMQIKDAGRVFYTQPPSPNSIKAELEIFDYEVEDDGETEKKGNYAPKKVDIPPNAPSIKSLMYKGGNAFDKYTRKFRLEKISEETEDAKAEDFEASGLLCILKACTSLEELHIQCTNFNTFISPVLLLKMQTAAPHLARTLKVLSIRGPLQLEPDALAWISDFKSLERLDISDAFSAEFYQDNYDYDCDHRTMSRPYDDQMMECIRSLTHLKRLDLGCGDGKSQRHLFNYMLGRPREIELW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2M6</accession>
    <name>A0AAD8Y2M6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ATP synthase subunit O</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_011462</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase delta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2M6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.20">
        <property type="entry name" value="N-terminal domain of the delta subunit of the F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01416">
        <property type="entry name" value="ATP_synth_delta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026015">
        <property type="entry name" value="ATP_synth_OSCP/delta_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020781">
        <property type="entry name" value="ATPase_OSCP/d_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000711">
        <property type="entry name" value="ATPase_OSCP/dsu"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01145">
        <property type="entry name" value="ATP_synt_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11910">
        <property type="entry name" value="ATP SYNTHASE DELTA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00213">
        <property type="entry name" value="OSCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00125">
        <property type="entry name" value="ATPASEDELTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47928">
        <property type="entry name" value="N-terminal domain of the delta subunit of the F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00389">
        <property type="entry name" value="ATPASE_DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="4" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1737690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="208" mass="22234" checksum="1D21B4C97F59D582" modified="2024-05-29" version="1">MLSNASILRKAATTAIRRSMATEAAHKPPLNLYGLNARYANATYIAASKSNTLDQVESELLAIKNSATTSKAFSSFLENPLISRDDKTKNVEDMLKGKTSSVTLNLMTVLAGNARLSSIVGITDTFIQLMKAKRGEVEATIISAEPLNKTMTAAVQDAMKSQFPTGAKVVLKSEVDPSILGGLQIQIGDKFLDLSVGSRIEEVGRTAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2V0</accession>
    <name>A0AAD8Y2V0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA polymerase epsilon subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">DNA polymerase II subunit 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_010651</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Participates in DNA repair and in chromosomal DNA replication.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DNA polymerase epsilon subunit B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2V0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008622">
        <property type="term" value="C:epsilon DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007185">
        <property type="entry name" value="DNA_pol_a/d/e_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016266">
        <property type="entry name" value="POLE2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12708:SF0">
        <property type="entry name" value="DNA POLYMERASE EPSILON SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12708">
        <property type="entry name" value="DNA POLYMERASE EPSILON SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04042">
        <property type="entry name" value="DNA_pol_E_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000799">
        <property type="entry name" value="DNA_pol_eps_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA polymerase alpha/delta/epsilon subunit B" evidence="7">
        <location>
            <begin position="303"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1738621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="553" mass="61967" checksum="9067BF287A17DA67" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2Y7</accession>
    <name>A0AAD8Y2Y7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RAD52 family DNA repair protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_010711</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RAD52 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2Y7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045002">
        <property type="term" value="P:double-strand break repair via single-strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.80">
        <property type="entry name" value="DNA repair protein Rad52/59/22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041247">
        <property type="entry name" value="Rad52_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007232">
        <property type="entry name" value="Rad52_Rad59_Rad22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042525">
        <property type="entry name" value="Rad52_Rad59_Rad22_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12132">
        <property type="entry name" value="DNA REPAIR AND RECOMBINATION PROTEIN RAD52, RAD59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12132:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD52 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04098">
        <property type="entry name" value="Rad52_Rad22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="255"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="330"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="379"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="258"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="297"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="330"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="405"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1738681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="417" mass="45765" checksum="AAC3C306D8CEE46B" modified="2024-05-29" version="1">MNSPHNDDTNITQHNPPLHEEPSPAQLTDATNEPMKNYDGSQMRDTNSQLVYKSQFLSTHPLWSDCKERVGYGGKKFTYVSGDGVIRNMNAIFGHGGWSSQILNEKLIQSEKDDRGRWYVGYLATVRVTLLNGASHEDCGSGEGINDSKIKAHEKAIKSAVTDAMKRAARHFGERLGNALYVKGNGIRTAPRTNRDALAELERKDSLNLFGNQAALRSVEEKKVASTATPPINNHDAIRTAAAATMTVSVGAATARTNSLPNQNHNSSNNTNTNRTSMHSARPLPPPAPSPIVSRGPLHQQHKQQQPQLQGVANANNFGGNQNNNIYLRQQQQQQQPQQRPTSHMAPPPRPMYNPANNAAGTTAYQLLNKQQQQVTVNNTTANDTSKRGLNNGGDDSTIKRQKLNPYSNNNNSRLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3M9</accession>
    <name>A0AAD8Y3M9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_010188</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3M9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1738872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="231" mass="25647" checksum="DBE7EF6A3DD819C5" modified="2024-05-29" version="1">MTSRRVIDVDVGGATNSAFAVLRASSIFIAQTSKLPIDQATCVLEDQHRSTVELQALEEVVEMVHGLCFNMLNGGIGSALGGCMSSSSWSCFILAKIASHNFDLNQSEHQMKLQLQLMLPQLLCSSAPSRSQAPFQPLGVTTTSNSEYYPEVEDFDMDFEDFDIDIDSADDVDSYAFDAEDEVDFEDEDAGPLGCSWSRRCWKTKCGCRKCKRQKVCAYARRRHPIATETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3Y1</accession>
    <name>A0AAD8Y3Y1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DUF91 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_011030</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3Y1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002794">
        <property type="entry name" value="DUF92_TMEM19"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00297">
        <property type="entry name" value="TIGR00297 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13353">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13353:SF5">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01940">
        <property type="entry name" value="DUF92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1738361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="350" mass="37203" checksum="EFA1EBA37F30F78C" modified="2024-05-29" version="1">MNRPSHHLYAAAVLLAASYNLSSHIPAALAFSPSHLQPSLLRTRSSSSFEFSSSSSSSFDNNHHIRQHHTSSNIQLQMDPTSTTEAITSSLTSLFQFTGPIPFLPSLALNFLLFFTLRPKLMTMLTPEGFAHSLALGTMLWTTLGWRGWTVCVLYLFLGQAVTKVGFEEKTKLGIAEGRGGRRGPENVWGSAFTGVLCAAAAAQGIEFLGLSSNVWLLGYVASLATKLADTFASEIGKAYGKTTFLITSLKPVPRGTEGAISLEGTVASVIGGFLLSIYAYGVVGLVPTLEGVGVATFAAFGGTMIESLIGATLQEKEGFEWMSNEVVNFFNTLIGAAIAIGLGVFVLGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y538</accession>
    <name>A0AAD8Y538_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase</fullName>
            <ecNumber evidence="6">1.1.1.302</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_009396</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; riboflavin biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.302" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y538"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="entry name" value="Dihydrofolate Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050765">
        <property type="entry name" value="Riboflavin_Biosynth_HTPR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38011:SF7">
        <property type="entry name" value="2,5-DIAMINO-6-RIBOSYLAMINO-4(3H)-PYRIMIDINONE 5'-PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38011">
        <property type="entry name" value="DIHYDROFOLATE REDUCTASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_8G06820)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="Dihydrofolate reductase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042197307" evidence="4">
        <location>
            <begin position="27"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Bacterial bifunctional deaminase-reductase C-terminal" evidence="5">
        <location>
            <begin position="149"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="Bacterial bifunctional deaminase-reductase C-terminal" evidence="5">
        <location>
            <begin position="302"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1739637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="469" mass="52218" checksum="7C2A8E4C87C326ED" modified="2024-05-29" version="1">MTRQLRCTSCAQLLLCVLFLASCCVSINADAAAQVNTAKTGISRQPRITAATDVKKIKNNATNSATDDQIIPSSNNTTALEKNNTIPVSSAENNITQKEVVDPVDSILSDISSWMKKQQANNAAQIDEQLFVDRDDSKYIQQPRILRRPFITLSYAQTLDGMIAAKLNNNNQTTTSNMKISSPESLVLTHRLRKMHDAILIGGSTFALDEPRLNARLPKPSLQQPMPIVLDTHLRHLQQILFDTIFPTDSTLLEEANIPTHMSVERIRATNPIICCSNQAAFSFIDLMEIFQDVHLQRKRPKTSYKIIVYKKIDENDHMEDACMPIKITVHVTHHNKKEEDVTQEVTFTLLPCPINERTNSVSLKHAMYQLCDQFEIRSVMVEGGAGILSSFLNECNDDDNDESELVHCVCVTIAPTVLGGLGLPSLGGLDALMKKSDEEDEIEESPTLKSIDGRFIPLGRDCVFLGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y549</accession>
    <name>A0AAD8Y549_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Transmembrane amino acid transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_010146</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y549"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF458">
        <property type="entry name" value="SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="289"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="339"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="455"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="481"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="526"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="10">
        <location>
            <begin position="59"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="28"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1738830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="546" mass="60879" checksum="805954B158204DCF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-06-18" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5G3</accession>
    <name>A0AAD8Y5G3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Multidrug resistance-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_009915</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000838">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000013">
        <property type="entry name" value="ABC transporter C family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF456">
        <property type="entry name" value="MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN LETHAL(2)03659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="252"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="347"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="749"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="816"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="885"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="914"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="999"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1027"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="131"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="455"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="767"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="1096"/>
            <end position="1332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1739372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1346" mass="148811" checksum="08970A1E0414D966" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5H2</accession>
    <name>A0AAD8Y5H2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009930</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5H2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="207" mass="23256" checksum="9957F9CC363FEDE9" modified="2024-05-29" version="1">MNQERGLQAAIGIVMAFSILWTLAILVPDDSSSSAVSMQRFDGLVVNGNHYVLDTNVDQTSSGEGYKVIHAVKTPTNVQVKKSRNTKRELNVASNPVVTSASIEPSTETASKENDSNEEAAKQPRMSSFSYAWFALFICYHARNFIKKKNRRVLRYGEEFFVKSGLDHKLEYGLEYEDDYSVDTSFYGSISTSSDFQKFDLDDDPFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5Q4</accession>
    <name>A0AAD8Y5Q4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009088</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5Q4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35213:SF3">
        <property type="entry name" value="MYB-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35213">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="689"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="708"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="725" mass="80159" checksum="4300DCCE6C47F100" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6Y5</accession>
    <name>A0AAD8Y6Y5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Protein PHYLLO-like protein</fullName>
            <ecNumber evidence="14">4.2.99.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_009195</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.20" evidence="14"/>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070204">
        <property type="term" value="F:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070205">
        <property type="term" value="F:2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07037">
        <property type="entry name" value="TPP_PYR_MenD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02009">
        <property type="entry name" value="TPP_SHCHC_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="entry name" value="Anthranilate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="entry name" value="Enolase-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="entry name" value="Enolase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01659">
        <property type="entry name" value="MenD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004433">
        <property type="entry name" value="MenaQ_synth_MenD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032264">
        <property type="entry name" value="MenD_middle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041338">
        <property type="entry name" value="OSBS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00173">
        <property type="entry name" value="menD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42916">
        <property type="entry name" value="2-SUCCINYL-5-ENOLPYRUVYL-6-HYDROXY-3-CYCLOHEXENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42916:SF1">
        <property type="entry name" value="PROTEIN PHYLLO, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21508">
        <property type="entry name" value="MenC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16582">
        <property type="entry name" value="TPP_enzyme_M_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="ADC synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="Enolase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="Enolase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Chorismate-utilising enzyme C-terminal" evidence="8">
        <location>
            <begin position="191"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate-utilising enzyme C-terminal" evidence="8">
        <location>
            <begin position="344"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme N-terminal TPP-binding" evidence="9">
        <location>
            <begin position="518"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="domain" description="Menaquinone biosynthesis protein MenD middle" evidence="12">
        <location>
            <begin position="720"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="10">
        <location>
            <begin position="1203"/>
            <end position="1503"/>
        </location>
    </feature>
    <feature type="domain" description="OSBS enolase-like N-terminal" evidence="13">
        <location>
            <begin position="1585"/>
            <end position="1634"/>
        </location>
    </feature>
    <feature type="domain" description="Enolase C-terminal" evidence="11">
        <location>
            <begin position="1751"/>
            <end position="1949"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="143"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF21508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1740245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2206" mass="240997" checksum="15241C8AAF8E5842" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7C7</accession>
    <name>A0AAD8Y7C7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Trypsin-like serine protease</fullName>
            <ecNumber evidence="8">3.4.21.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_009729</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7C7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000002">
        <property type="entry name" value="Transmembrane protease serine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF91">
        <property type="entry name" value="AT26814P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042006613" evidence="6">
        <location>
            <begin position="27"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="7">
        <location>
            <begin position="86"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="45"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1739970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="412" mass="44727" checksum="08C7D98695432E99" modified="2024-05-29" version="1">MMNMTNKVLLCALSSALLLFHGDVAAADNSSGVGDTISARKLKNHRMRPHDEQPQGAAPQPQQLRGSVDTPSQTQPPPFRPQQTRIVNGDIVAGKNSGYPFQVQVGGWLCGGSLIAPDVVLTAAHCIIGGSPSRVNIWDASRGRMTPRTVQSAVMHPRYKSDGLSDDIALIKLSEPALAVTADWDLVSNYDWGNHPPMIRLQRYQTPSGCTSLSQDQAEDITTMTVIGHGTVAYGGQMSGQLLEADVHYVQNSVCQKQYKNEDITDDMLCASDTQEGQDACSGDSGGPLFTRLPADGGHDLFTLVGTVSWGYGCAMKEYPGVYSRVAANTDWIDEKVCGGLSPKSCNADDGKIRDYALESLTGGTSVSRRRTKKNVITNNERAALYGDKVQEEPYDTYEWKLKKGRTPQQRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7I9</accession>
    <name>A0AAD8Y7I9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MACPF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_008708</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7I9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020864">
        <property type="entry name" value="MACPF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01823">
        <property type="entry name" value="MACPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="MACPF" evidence="3">
        <location>
            <begin position="387"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1740613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="822" mass="91464" checksum="99554B3BE047DDE5" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8A6</accession>
    <name>A0AAD8Y8A6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8A6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="335"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="372" mass="40735" checksum="1F2AAAC4664B63A9" modified="2024-05-29" version="1">MTSSTNNNDDTTTKATCGISSPLASCTEACQSISNIALPSNELTCLHPVHYFKLHNPNNHHVDDYEAHHEDHIAGSGSPVMYSNHAPMLMSRGLTKCEYCGSSNVDRCEGVREVHDHFGEYQRKMFGQHYDAGNHNHNHHGNAVENDESQYYNTEDDYFHNTAQHNTTNDNQYQPNNHNDAHSTSSTSTSSQPPPTCHRPKLFFLKKRPPFANSNDGWNIQTQHRQHLFEPPSSMEGVGRGYGEVRGQLGDYCTVNYASPKFLNGSGGNNGMVSMKKGYKMIQRSHSLPVGVAGGSSLPGNGGGEACGSVCGETEITFLSASHNGGRRSTVVRMSSHNGTTTNNNDSDTGRSLSPLQWVNGSEIKGVMNWFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8J4</accession>
    <name>A0AAD8Y8J4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8J4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="139"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="216" mass="24844" checksum="AB4BFE6C04A850DA" modified="2024-05-29" version="1">MPPFYNDEQPPPQRTSYDINDDDDEIRSILSHKSLSYVTIETKVADAETLSTRLLEDYMDDDEDTHFCVSFDSKRPFLILSCFYMILVTVNIIILSSTEDVHSTNWYKICNVVNVVSGYLGIVAAIYRSKVVATMVSCWWLFEMFFGMFRLALMYWSIIPDTAARSWFIAYTVISYVVRLLLVGSAIMFVSQDDGGEQTDVTFRRNDNDDAMVVFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8Q3</accession>
    <name>A0AAD8Y8Q3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007452</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8Q3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042274339" evidence="2">
        <location>
            <begin position="31"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="514"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="601"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="524"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="536"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="604"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="619"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="641"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="653"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="681" mass="75621" checksum="1E1F7F92D5AA34B5" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAL6</accession>
    <name>A0AAD8YAL6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC1 kinase family protein</fullName>
            <ecNumber evidence="5">2.7.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_008023</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.-.-" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAL6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05121">
        <property type="entry name" value="ABC1_ADCK3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050154">
        <property type="entry name" value="UbiB_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566">
        <property type="entry name" value="CHAPERONE-ACTIVITY OF BC1 COMPLEX CABC1 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566:SF123">
        <property type="entry name" value="PROTEIN KINASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041990998" evidence="3">
        <location>
            <begin position="40"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="4">
        <location>
            <begin position="308"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1741545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="644" mass="69629" checksum="48418B3693DD661E" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBZ9</accession>
    <name>A0AAD8YBZ9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006610</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1743013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBZ9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="315"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="501"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1743013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="582" mass="65168" checksum="E3DD0D7097E16F54" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEF7</accession>
    <name>A0AAD8YEF7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Trafficking protein particle complex subunit 13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004109</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEF7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990072">
        <property type="term" value="C:TRAPPIII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010378">
        <property type="entry name" value="TRAPPC13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055427">
        <property type="entry name" value="TRAPPC13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13134">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13134:SF3">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06159">
        <property type="entry name" value="TRAPPC13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trafficking protein particle complex subunit 13 N-terminal" evidence="1">
        <location>
            <begin position="2"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="279" mass="30483" checksum="D8DC8CF2E65D5EEB" modified="2024-05-29" version="1">MVAQLQTPSRRILLPTALDARNNNNSSLREVAPGEGVDALISRRLEEVGQHILRVEVSYDSGGAKTLRKFYRFNVTNPLQITAQSVTRSGDATCLVSINVENIMDKQGVTGGAVAISSIGFDAADGLSAMEINVEDESDESNDPAQNIKQRQSAVELYDSTVILHPGDSYQYLFSVSAESEAAALRGIACGDELGKAVVVFQKTMGELGKIYSSPVMCPPTSFLKEDGTQNSKFVTNASGFRWMWLLLQPSDLPHLEEETGVWMKYFLSLLNQLIHPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEJ9</accession>
    <name>A0AAD8YEJ9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterogeneous nuclear ribonucleoprotein Q acidic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEJ9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21039">
        <property type="entry name" value="NURR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041337">
        <property type="entry name" value="hnRNP_Q_AcD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18360">
        <property type="entry name" value="hnRNP_Q_AcD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterogeneous nuclear ribonucleoprotein Q acidic" evidence="1">
        <location>
            <begin position="150"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="222" mass="24227" checksum="B43A08620F901E0D" modified="2024-05-29" version="1">MPMQMGQQMPGLLPGQTQMMPAGGMQQPVQPQQMGMGQQGQYYQQPQLAQQQPMYSNNNVSQQVQSVNNAALGQALMPQGMMGMQARGSQVNRPSMSQNQGQLPLDILALADKASQALSSVQPPANPNFPPPPMQQQSFQQKNFASEQDLSTLVQYALQNLRTTGHVEQQLDGKICSMLKRLPEHAALQALETFSSCDVSKMRSKGGYLAGILKKELVKLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YF19</accession>
    <name>A0AAD8YF19_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Signal recognition particle SRP54 subunit M-domain domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004439</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YF19"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1745148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="246" mass="27415" checksum="EAE75C8351AA57F4" modified="2024-05-29" version="1">MTAGSRLLHQSLVTVRRMHTTCKSYGAQSFGAKAMVNSISQLPSTSSYNNYNQSTPAAASIQKVSFSSESSEKPGIFGWVQEKFTQREKDKQAVKLVDQINLMANSPSYTLKMFADEVDEQLSSWKTKIPGMGSSSEIQAAKESQVVVKEMVTQLGGDISAGDLGKLERKQKLKLSIACEKPLDDINRVLDLFRQMEIMHRILRYRKENGLPLPTDQAGLNMAMQQDGMKVMTNQEKKVLRKAFGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YF83</accession>
    <name>A0AAD8YF83_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Actin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004529</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YF83"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="326" mass="34923" checksum="09EED9BA67DFD4F5" modified="2024-05-29" version="1">MGSETAVATKKPPATGDGKTTAASTQAKRNRVTSKDTTSPACIVVDNGGWTVKYGLVPPINQNNNGPGSQIMSTMYNATARPPHQLTVLTGDEITKRMKNLGQLTWNNSMERGMICDGETQLRVWARTLEVLGVVPTPQIKGGGFLTLQGASAAKRRGNAAAAAASVVDASSATSNASIPKYSSNNCTFLLLEPPHVPSVISEGVDCILFRELGVGRVARMLGPCMAAVKYLSIGKKSTDSNENATTTKSEWLNDDTNCCCVIDSGYSFTHVVPTHRGGAMTKAIRRLDIGGKVLTNLLKEAVTYRQWNMMDEYHIVNDAKEQLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFF0</accession>
    <name>A0AAD8YFF0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005557</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFF0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1743960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="145" mass="15962" checksum="2A27A7B73A9BF324" modified="2024-05-29" version="1">MKRIEANDPIALYFMGTHRYQEGDYEGACEYWKKAAELGGAESHFKLAGFYCGEKEARFHLGFFRDFANGRADAAVKHLIIGANLGHDDSIKALKGCYIKALKMGVAGYELISKENFAAALRAHQAAIDATKSPHREAAAKFCAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YG83</accession>
    <name>A0AAD8YG83_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005104</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YG83"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042159510" evidence="2">
        <location>
            <begin position="19"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="347" mass="37062" checksum="B121655E7B79E9FB" modified="2024-05-29" version="1">MNFSIASILLATAAAASATTTSSKAYRIFSVDPRPKAGKASNSVISVSEGSLVTAKSTKNLILSSSLPLSYNSKTGKQAKMVKSAKAKVAKCIDQSVSMSLSTPDVVRRVLHDANSSLSASFSMETKAAKSKMSKCLPMSVSMSIETTAMPTYYPSYTPTDEPTDVPSQAPTTRRPTQVMVCQSGDFVDALGRDCFWYEAPNIELGCESLSSSEGELTNKGKTPWDECCFCGGGKMVALNTTVPDPDRKLAVVDESKDVVEQKMGVDLEVVPADANSIVCISNSYFVDPLGRDCSFYVQENIQEGCESLHGHGDMANEFSWTNDDGKTPWSECCFCGGGTLGYESSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YG90</accession>
    <name>A0AAD8YG90_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_003627</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YG90"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="70"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1745703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="403" mass="45217" checksum="2B440DA6CD6F5917" modified="2024-05-29" version="1">MPSSKKKKSKQKKAANVAAAASNLSVNDDPYEFDGEIAVEQLNNARAAVGLNRVDPRPKKVDRLPDYPACDGCGSEYSGTMECTSCGSAFYCGRSCQVNHWKNGGHKDECPTLKERSQSIAKTTVEKLMDESSPPLLRVQVLHDDPLDGSGPYKFAVDYGLHDAIYSAFLVDKEGVVENHTNENPLYRCCLTQWIMQSLFRGERISRQIHHGSNSFGKVDGGRILGYLHSHSDDGLQVWWKASLESAMVFLHSKISSTPDESFRCHQMARDIWAMWTHTFASKRASECILLTHDKAACLERATWMIKQMKPYLSKLQSAREGLDRNEVIQAYFNQVPAMIAAQCRELANVTSVDPVKLLKLRGLDKKMYENIAKPHGEDMIRRKRAADTARSRDILKRAGAFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHS1</accession>
    <name>A0AAD8YHS1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002143</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHS1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042149626" evidence="2">
        <location>
            <begin position="19"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="434" mass="46212" checksum="286F247633398F2B" modified="2024-05-29" version="1">MKFHSKCLIVTAAQSVAAATSSSSSSYSSSITSSSLTLSYKPYQSSISANNRNEADIFTIIDCIRGGAIEVDSPKKKKKSSKSSKTKGTTKTNTPPPTTSSDEEDEDAKLAINTAMKDSDTAHTLGEAIRARAHILRKDKLPYAERTFDSALVSLGLSLGTAGLDVDEDDIVSISTDGVEEGDEDAESKATTTTMAYYQYGHNNNSHQQQNQQYVQPSTSAVIANYFLKTHGGTHLLQCVLSLLASVLGMACLVLPPFPSAAALVAAATASNNNNNKVATVTSVQLSRRILNSTTKHQLLQQTLLLAMAKHVSALVGAVILGAQRIPTLGIRNARRHLELVALDPVGQYLFYCSILVVWLGWFGGGNNGSGVEFVSGLRRSVISIQNTASAAVAGGAENAEVEAMSQLLDVLSQSSPPWFYLNLMVVPLYQSSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHS8</accession>
    <name>A0AAD8YHS8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Histidine phosphatase family protein</fullName>
            <ecNumber evidence="1">3.1.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_003165</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHS8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051710">
        <property type="entry name" value="Phosphatase_SH3-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16469">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16469:SF27">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="228" mass="25268" checksum="A822CF4BCEAF7A3F" modified="2024-05-29" version="1">MDIVAEDVVYLTRHGARIDSDDSEWLKKCNHNRSDDPHLSPSGHIAAQELAKRLRKTLPGNHIKHIISSPYIRCVETANAIAEELNIQIKIEPGIAEVNSSRNPQFLDTEQLQEQFPSIDSSYTPVMTREGLPLEYSDGACANRSATAARKVRRKLTGAILFVGHGASCYGVADEFGHRGYVGYTSLTKFSQHDEESIDWMAWSVHAEGLGIEILPIGSAKNHSCRKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YI15</accession>
    <name>A0AAD8YI15_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003779</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YI15"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042278625" evidence="1">
        <location>
            <begin position="21"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="88" mass="10268" checksum="24CC006810EC6EB6" modified="2024-05-29" version="1">MYMICIVEVLMLNLLDGVDNSEFKMKFKNTPKLKLTSLRNLSRLHTADMQNACKLYGNFSKKRHQTLKFVALQRKHTQLCADQTPKTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJB0</accession>
    <name>A0AAD8YJB0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002828</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJB0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="216" mass="24768" checksum="93B210464F9C0FB0" modified="2024-05-29" version="1">MIYDSMMSHMLQVTAGLQDDCLHSAILDWIILGRYGGFRQSEWCQTSQSIAMTRPSLALPVQEPLAFIPSDLAFFDNAGRPLPDIEDDSVDMVELTWRFQKNSNNGERIPFKRDYSSPDLCPVLVAVRIRRRAACLGIHSASTLAVYSDPKSVTGYSYITANQTAAFLRTTAQKVFMLDSNDDRLQRWSCHSLRVTAHYRSRFWWKHFRRLVGLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJI2</accession>
    <name>A0AAD8YJI2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002832</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJI2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="688" mass="77824" checksum="B7D622B43FB7DFB5" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJK1</accession>
    <name>A0AAD8YJK1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJK1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="95" mass="10562" checksum="5BD55560DB8B872D" modified="2024-05-29" version="1">MTLRTILLHTTSATGMSLCQMNNHPDFRLRVAKQKFGGGGANITVKQQPATASNNKRDFSSKSVPNYKKQVREGGLNIHLLENPVDRMTVRPVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YL45</accession>
    <name>A0AAD8YL45_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_000520</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YL45"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1748581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="96" mass="10969" checksum="91D64B008B23E9B0" modified="2024-05-29" version="1">MQCNVGDEGMHAELKQLYTHVTDVCTKAMHVGCARWTAPAQYAPVAGNKRLRMTYFYPGQFSGNNTEEQYPDPVCGCFCRDHATIIQEKRHKENSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLN9</accession>
    <name>A0AAD8YLN9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ABC1 kinase family protein</fullName>
            <ecNumber evidence="4">2.7.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_001478</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.-.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLN9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05121">
        <property type="entry name" value="ABC1_ADCK3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050154">
        <property type="entry name" value="UbiB_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566">
        <property type="entry name" value="CHAPERONE-ACTIVITY OF BC1 COMPLEX CABC1 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566:SF121">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042228658" evidence="2">
        <location>
            <begin position="21"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="3">
        <location>
            <begin position="281"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1747515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="677" mass="74685" checksum="112405D56E3D1889" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMX1</accession>
    <name>A0AAD8YMX1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000194</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMX1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="187" mass="19665" checksum="D25FB8223C872505" modified="2024-05-29" version="1">MMDSTASAPATPVEDNVAGGEQDPWATLAAAAGEEPPSEAAAAESSNNNPSTEPIAVSHAEGETFSMPETNAPPSKNEFLTAVTNLGSVITAKAQEVDQQHHVTEKLASVKLATAAKTGEINEKYQVSEKWSNLTRTMTVKVEKVKEDPKTKEATENVKKSLAGASSWVSQKFQAIKTPPSNNGGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D492</accession>
    <name>A0AAD9D492_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_016858</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000066">
        <property type="protein sequence ID" value="KAK1732464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D492"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1732464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="500" mass="55966" checksum="EFA8D8C0953CB4E9" modified="2024-05-29" version="1">MMSSNTLISPTELANSLLKTTYSANEAKVALDLLCAGLQDFGYDATPMITKHCPGDASAPITDPRHKGVRYGDDRNNSQFLYCKKCTSYNDPVLAKTYGGNFQCTVIGSFVFPKTNRVLTDHKEVMLTALYPHPTECCTSTLHMNNETGGWAIIPFDFENIIGKSLDRIIDNISGLTSADLGNGNNKYSKLLTSGSQGLPHDRRFFIPIDPLKSPDIMTDDDTSQDIVNNTHGLLDDTFVKEFQQLRTRLTLFLANQRGIETELQFEMPHHPDNVGVCWKPLLTDEQHLSLVNPSVLFGGYMPKREGRVKQLAVNQIPHCDFGAVNGTPLSDNILLRNKTLPCTVLLPLLDHRTLMIYKDDDDKTVVHEVKANKGELIIFDGDVSHGGYTYMETTPLQLHPCLHFYMYSTLHKSDLSSFDVDVHATCNLAEQFASVLKPNKYTLINKEIPRRIADVDKAYTRLNKAGLLNDAVKQESILAMEELLCFMRNGTRMKLRGTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4R5</accession>
    <name>A0AAD9D4R5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Mitochondrial carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_016289</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000055">
        <property type="protein sequence ID" value="KAK1732958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4R5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45667">
        <property type="entry name" value="S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="71"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="157"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="257"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1732958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="355" mass="37881" checksum="6617EC21934EAB1D" modified="2024-05-29" version="1">MHSKPEIGRRGFIGSCAALATCTVLAPSSSNASPLHQTSDTTVNSNLIASAAEQEKISINPTTIPALTSFQESISGFISGSAVSTVKTLVKYPLDTATVRLQMPNTQYTLQNLPKLFSGSFDGIVAPLLSNIPAGAVFFAVKDATKSALKNSHTGLPQWALTSAAVAMALPPYWLIRNPSEVVKTRIQVRAEGYYEGMSTIDAFQLALAQADGNSTKAGISELYQGYSENVLYGFPADIIKFVVYDYLSGGKGKSSVSPGEGAVYGALSTGVAQLVTTPLDVLRNRIMAVSKEEQDRDVKLSYVDRLAKIAKEEGVGELFAGTTPRVAKAMLSGAIQFATYEETKQKIGQFFIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4V9</accession>
    <name>A0AAD9D4V9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_016232</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the hemerythrin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000054">
        <property type="protein sequence ID" value="KAK1733094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4V9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.50">
        <property type="entry name" value="Hemerythrin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035938">
        <property type="entry name" value="Hemerythrin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47188">
        <property type="entry name" value="Hemerythrin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1733094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="284" mass="31937" checksum="701AF6DE1A350ADF" modified="2024-05-29" version="1">MAEVVGDFYVHLVDGAEVSRDLTSSTKLLTSKKIPTVMHFYDGGYGSRVQFLMVCVDGARVAIEFGRMFDLKAVVNCYIPSRGYMPVGFGQLGCSGFIISDEKGYFVSRKTRAYLQYGELAFDHVEQILEKKCSVVPARHEVLVEEEKKADEDVLSKNWVMPSVGIQTMDEEHELCEGALSLMLLKPNTQTLTKVMEALTEHFQHEEELMKQAGFGRPGEPFSPYANHVKDHERILDIGYVELAKKSEPNKSFLNFTCSETQLNEPYKSFVAMTCSDVSDEKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5T4</accession>
    <name>A0AAD9D5T4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pentatricopeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_015238</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1733980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5T4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051222">
        <property type="entry name" value="PPR/CCM1_RNA-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47942:SF63">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47942">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT (TPR)-LIKE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042121555" evidence="3">
        <location>
            <begin position="31"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="291"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="302"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="324"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="357"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="368"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1733980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="766" mass="86181" checksum="2043AB366445C1AC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5V9</accession>
    <name>A0AAD9D5V9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nuclear pore complex protein NUP54</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_015296</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1734038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5V9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044613">
        <property type="term" value="C:nuclear pore central transport channel"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006607">
        <property type="term" value="P:NLS-bearing protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006999">
        <property type="term" value="P:nuclear pore organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036228">
        <property type="term" value="P:protein localization to nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024864">
        <property type="entry name" value="Nup54/Nup57/Nup44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025712">
        <property type="entry name" value="Nup54_alpha-helical_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13000">
        <property type="entry name" value="NUCLEOPORIN P54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13000:SF0">
        <property type="entry name" value="NUCLEOPORIN P54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13874">
        <property type="entry name" value="Nup54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin Nup54 alpha-helical" evidence="5">
        <location>
            <begin position="255"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="398"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="466"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="14"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="468"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1734038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="489" mass="51256" checksum="3F115EAD2913C15B" modified="2024-05-29" version="1">MVTWGNNTTAVYGTTTPANAPTTPAPAGSGFSFGAPAAPSTPPSASQKPAVNPPPLGGGGFGAPAAGGGFSFGGAAPAGAGGLFGSTAAPAPSGGLFGSTTPAPTAGGLFGSTPAPAPAFGSTAAPAPSLFGGFGAPAPAAPSNNVFGSTQQQPHQQYNTQQTYNPQQAALHAHQSASQRQEAARIEEAIFNLHSKYSPHASDPLNPALASNNIPSSLCAFTAILYDPLPPEHRINNTTASAVGSRGGGHLSAPKPSHISNQVWNEALARNPDPNELMPTPLVGSTSLHTRIISQQEKANALNAHATKLRDTLCFLQQTARSSQEHITHLANTQEELNRRLLEIMRKVEIIRCMNQPTQRAEEEANFKLRKLLEQVNLVAVRLRDLEERGRQQARNWRMRGATQLQQQRNGGGMDGTALSEEDKLALFHVLNDQRLGMERLGSIVTRDVRDTDILKEEMNKAESVVRGGSGGRRVGGALGQSPAIFGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5W0</accession>
    <name>A0AAD9D5W0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">SAGA-associated factor 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_013865</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the SGF11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5W0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070461">
        <property type="term" value="C:SAGA-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013246">
        <property type="entry name" value="SAGA_su_Sgf11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08209">
        <property type="entry name" value="Sgf11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0010">Activator</keyword>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="20"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="111"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="27"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="115"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU261113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1735251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="135" mass="14396" checksum="6DC8048467A69574" modified="2024-05-29" version="1">MMGEAHDAVVISSPADDVVGAASSAANQDGNTVDMNKAQTKSEAPTDDKRKGDPEQEDASETKTSSARYYTDIYGRVPGKEPKYPIPCPNCKRELAVSRFCQHLEKCMGLGGRGVSSSSHSNSSGSQAKRRKSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5W3</accession>
    <name>A0AAD9D5W3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015328</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1734070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5W3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="148"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="227" mass="24223" checksum="9332817E067B4040" modified="2024-05-29" version="1">MKSIVSKFGFGRPQSKGGEQPPPPPPPQQSSTSKTSRRSSSQSSSSSSNSTKLRNNTTAAANAATTPLLSTMITSSSAVETTLNSTRSSGYKSQSNPNNRAQQQQQRPTNPQTNNKHGILHKPRTSPPKQPIPHEPPTSRVRFAPQTPNSGNLSSLSSTTSSPSQVHLMACGASVASLSVVSKDSIFDRVLKEENERLNAMGMGGRDSPEKGEGKKDKMRGGRRVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5Y5</accession>
    <name>A0AAD9D5Y5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015133</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5Y5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="2">
        <location>
            <begin position="231"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="508" mass="56702" checksum="6E40392E0DE631CA" modified="2024-05-29" version="1">MNPHCSNQPAASALPPEPVPMKQWTVAVINSLRSRGGDDNKRNVDKIVCSREYMSCALTIAHSLADQLCTVEMERGYKQKSSSQPNCNNGNPPPTIETSERSWSESISVYCPKTKASEGKKDKVSDANFEPLSYEGDNLEPEDFQHLERQLSTLLFDNDNKQPVDYSDVRGAILNEDAVHTKSLSDNGKLQIRSLEVRDDLKLMIDCPNLYLEDVDLTKAVNVGLQFGISLYGREAELQTLKECYQRSTSSECEVAMICGTSGIGKSKLSQEFARSLSEDGESIFLSGRFDKLESQPLHAISSAFDAYCYCAWVTVEYQSMAEKVSTALRRNLGEELACLVTAMPNLANILGDDFKSNQSNKSNNAVDAQKRLRYLFCQFVDVILRCHEGPLILFLDDCQWIDNASIVLLNQILMMTGSAKDHRFFFFGTCRDDEMGESHPLNLMLTNVNSLCGTRTTKICLTSMSKSALNEMVSTELSLLPRITRPLANILHHKTKGNVVYITIVMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D685</accession>
    <name>A0AAD9D685_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">60S ribosomal protein L8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_013986</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D685"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000020">
        <property type="entry name" value="60S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.950.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000006">
        <property type="entry name" value="60S ribosomal protein L8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="entry name" value="Ribosomal protein L2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_uL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023672">
        <property type="entry name" value="Ribosomal_uL2_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_uL2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022671">
        <property type="entry name" value="Ribosomal_uL2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_uL2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Ribosomal_uL2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007180">
        <property type="entry name" value="PRK09612.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691:SF16">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="RIBOSOMAL PROTEIN L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002158">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00467">
        <property type="entry name" value="RIBOSOMAL_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 10" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL2 RNA-binding" evidence="9">
        <location>
            <begin position="11"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL2 C-terminal" evidence="8">
        <location>
            <begin position="96"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1735372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="257" mass="27957" checksum="73AB462038A38C62" modified="2024-05-29" version="1">MGKYVQAQRKGKSPIFKAHIRTRKGAVKLRSIDYAERRGYVRGVIKDIMHDPGRGAPVAKVQFLNAYRYKRDTELMVATEGMYTGQFIYCGKKATLTIGNVLPLRGVPEGTIVCNVEAEVGDRGAFARGSGCFAVVISHDEDKGTTRLRLPSGGKKTVKSDVRAQIGVVAGGGRTDKPLLKAGRAYHKYAVKRNCWPKIRGVAKNPVEHPFGGGNHQHIGRPSTVSKAAPSGRKVGLIGARRTGRLRGVKKLGQDRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2024-10-02" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D689</accession>
    <name>A0AAD9D689_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014952</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="14" mass="1556" checksum="06E7FDEE8B230954" modified="2024-05-29" version="1">MSLEYGNIKTTSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6G8</accession>
    <name>A0AAD9D6G8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014587</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1832"/>
            <end position="1881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="196"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="302"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1836"/>
            <end position="1866"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1881" mass="207010" checksum="E1117E75CEB6EDE1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6Y3</accession>
    <name>A0AAD9D6Y3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_014124</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6Y3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16448">
        <property type="entry name" value="RING-H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="268"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="159"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="112"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="159"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="201"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="242"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1735058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="359" mass="41068" checksum="75E786D70C228944" modified="2024-05-29" version="1">MSSNRSSDYSPVSDFIIWGIFAFIFIIVPFLSVPLRCLVERICRCLGFETDQQDSESVDSDGRPIYSVRDRDYEYLSHRTKNQINEIRDMEISKRLAAFSLELTAENMISRQHDKDGHDKDEHGGQEEYNASQDSCCIDEEDPKETQDEANHFTLQEKYEEEEVSNASNDDTEASTETSNSEEEANYTHVCLPLPGYNKNGLRKPKKKKSSSSTPDSNNRIGLAFFRRRKKDSSKQTKELSGEDDDAEVTEQDITQQKDDRREVPIFCAVCLGEYETSERVCWSSNTECTHVFHHDCMLQWLKSLGKRACKQQRFSENPSVQQVLNFTMECPCCRQSFIDKSVDVDVDVGAGVGDDENV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D736</accession>
    <name>A0AAD9D736_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sideroflexin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_014289</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sideroflexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D736"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015075">
        <property type="term" value="F:monoatomic ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140300">
        <property type="term" value="P:serine import into mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004686">
        <property type="entry name" value="Mtc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11153">
        <property type="entry name" value="SIDEROFLEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11153:SF8">
        <property type="entry name" value="SIDEROFLEXIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03820">
        <property type="entry name" value="SFXNs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="421"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1735223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="474" mass="51862" checksum="3B04BF5691C3A289" modified="2024-05-29" version="1">MKRAQLRSVAASVAVVVATTTIMMMHSGCNKANAFSTNNVTTKKSTYTRTYSLQAFEIDSQSLSNTKVNSLRPVLPIAQRTRFQGALALIAIITTSNNGLQFQAVPIGESLLALVASIVLVSGATDAVERITASSTDAIPAYSENGCRYNQSIFFGRYCKMLLACDPRLLLYTEDEVRQYYKLAYVDYADVRSNAMKEGATYSLAETDRLLWEAKRIADSALHPETQEWIPRPCRMSGYLPYNGPICIAMVSVQSTIPLLFWSWVNQSQNAAVNYFNGPKSTSSDDDATTEIDGTLFKSYSLAVASALIVAFGLATYVQTNFSGEEANELLRFIAFPSAVIASSLNCYIIRSPEIESGAPLLNEQLENVLPGETSSAAAKRGVFSTTASRAVLQMPTYFIPPLLLDTVTPLKQFLVEDSLMVVPVTTFLLLVSFGIGLPAAVGIFPQVSSIKAEDVEDKFRDLGYEEFYYNKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D819</accession>
    <name>A0AAD9D819_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Prostaglandin dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.232</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_013289</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.232" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D819"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047034">
        <property type="term" value="F:15-hydroxyicosatetraenoate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05288">
        <property type="entry name" value="PGDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041694">
        <property type="entry name" value="ADH_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045010">
        <property type="entry name" value="MDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205:SF42">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE, ZINC-CONTAINING (AFU_ORTHOLOGUE AFUA_7G04530)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205">
        <property type="entry name" value="PROSTAGLANDIN REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16884">
        <property type="entry name" value="ADH_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042130520" evidence="2">
        <location>
            <begin position="25"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="3">
        <location>
            <begin position="328"/>
            <end position="669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1736153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="685" mass="75408" checksum="3F6CCD9BDE6E18B0" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8K9</accession>
    <name>A0AAD9D8K9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Trypsin-like serine protease</fullName>
            <ecNumber evidence="8">3.4.21.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_012274</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8K9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051201">
        <property type="entry name" value="Chloro_Bact_Ser_Proteases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43343">
        <property type="entry name" value="PEPTIDASE S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43343:SF3">
        <property type="entry name" value="PROTEASE DO-LIKE 8, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13365">
        <property type="entry name" value="Trypsin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042196164" evidence="7">
        <location>
            <begin position="22"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="59"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="348"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="449"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="789"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="900"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="354"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="476"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="496"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="532"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="789"/>
            <end position="806"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1736829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="934" mass="99448" checksum="32F5529EDCE23C6E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9Q9</accession>
    <name>A0AAD9D9Q9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011383</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9Q9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042051356" evidence="2">
        <location>
            <begin position="24"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="519" mass="58304" checksum="974A319A487F0A3E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DA07</accession>
    <name>A0AAD9DA07_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Dihydrolipoyl dehydrogenase</fullName>
            <ecNumber evidence="11">1.8.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_011444</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + NAD(+) = N(6)-[(R)-lipoyl]-L-lysyl-[protein] + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15045"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="1.8.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="9 11">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="11">The active site is a redox-active disulfide bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.4" evidence="11"/>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DA07"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045252">
        <property type="term" value="C:oxoglutarate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006103">
        <property type="term" value="P:2-oxoglutarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.30:FF:000001">
        <property type="entry name" value="Dihydrolipoyl dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000001">
        <property type="entry name" value="Dihydrolipoyl dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050151">
        <property type="entry name" value="Class-I_Pyr_Nuc-Dis_Oxidored"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006258">
        <property type="entry name" value="Lipoamide_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01350">
        <property type="entry name" value="lipoamide_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22912:SF223">
        <property type="entry name" value="DIHYDROLIPOYL DEHYDROGENASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22912">
        <property type="entry name" value="DISULFIDE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="FAD/NAD-linked reductases, dimerisation (C-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 9 11" id="KW-0274">FAD</keyword>
    <keyword evidence="2 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 9 11" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 11 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 11" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="13">
        <location>
            <begin position="35"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridine nucleotide-disulphide oxidoreductase dimerisation" evidence="12">
        <location>
            <begin position="382"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="482"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="176"/>
            <end position="178"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="215"/>
            <end position="222"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="348"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="354"/>
            <end position="357"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="10">
        <location>
            <begin position="73"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1738150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="503" mass="53050" checksum="92131260ECB0A314" modified="2024-05-29" version="1">MLSRAAFTIRRSAISSSRGGTASFFSTSTPLQDQYDVVVVGGGPGGYVAAIKAGQMGLKTACVEMRGSLGGTCLNVGCIPSKALLNSSHHFHDAKHHFADHGITISGEVTMDVAKMLEAKAKTVQGLTGGIEHLLKKHKVDYFKGKGSLSGPNGVDVTLNDGGKESLDTKNIIIATGSEVTPLPPVPVDNAGGKIVDSTGALDINKIPNKMAVIGGGVIGLEMGSVWSRLGTDVTVIEFMDGLCPAMDKELTKKFQTTLKKQGFKFKLKTKVVKSEVVGDGVAITTEPSKGGDQKTENYDVVLVATGRRPYTDGLGLESLGIQTDKLGRIDVDSHFRTAVPSIYAIGDCIDGPMLAHKAEEEGIAAVETIAGFAGHVNYDAIPGVIYTFPEVASVGKTEEELKEANVQFNKGTFPFQANSRARANGTGNAEGFVKILADKTTDKILGVHIMGPNAGEMIAEGVMGMEYGASSEDIARTCHAHPTLSEAFKEACMDAYDKPIHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DA44</accession>
    <name>A0AAD9DA44_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_010539</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DA44"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1738509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="308" mass="35495" checksum="7B3F8BC4E075F89C" modified="2024-05-29" version="1">MDMDNNKSRSWGRLRVVTTLKSIGISLFLLCVLLRNVQFTSIDSREDHTISNKNVMEILSTTPVEKIVLLGERHSGTNWITDHLTACFQDDHIKHWFQEDDPQQVPEESAVVVVMFRDPYTWVEAMREIPHHAHNHINLTQYDPNRNGSSWRRKGGRHLEWKEFVTRPWIGKTDSKRGDGIEGLGPNKYELQYDGSGRAYSRIIDLRRDKIINHLSVANFVGTRAFLPMRYEDLNANGTSVLLRSIEEAAGLKANCSAIIGKGGRRLKEKKITKHSKLSAEFIDWMNEFVDWEVEGRIGYYKRDASDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAJ3</accession>
    <name>A0AAD9DAJ3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_010290</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAJ3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013111">
        <property type="entry name" value="EGF_extracell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051022">
        <property type="entry name" value="Notch_Cell-Fate_Det"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24049">
        <property type="entry name" value="CRUMBS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07974">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1 4" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041929223" description="EGF-like domain-containing protein" evidence="7">
        <location>
            <begin position="28"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="8">
        <location>
            <begin position="166"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="287"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="320"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="197"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1738974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="361" mass="38254" checksum="0678C3323F8FE2DC" modified="2024-05-29" version="1">MWKPLFTTPIASAIVIVASTTGHSALAANPRPPPAQWMACPQAPSLRCANGSVCKEGVASFDSKHDHLNLQTHESGYYCECMDGFIGHECTIEVEDCENSIGYSPSDPTGVLMHSCYHGSTCKNFGNGNTMCDCDQLNLNSAPDATKFAGLMCEHESTSLCAVSLVGMSAPNDQFCTNHGRCKKEVLEGAPHPKCDCRNGWSGDHCEIRSDVFAKASQSFGKNYSQGQGVSGMSVGGKVMFSFILIALVAVLIGIAVLVYSQIKKNRGPREKAVGITAADIGAGEIEMDGSSTMSPPKSVFSGEGDNGGESGYDNHDLASDDDLALDEEDNVAARDDGDQAFTITDSHEDEEGSDSEPTIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAM3</accession>
    <name>A0AAD9DAM3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pentatricopeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_008551</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAM3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051222">
        <property type="entry name" value="PPR/CCM1_RNA-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47942:SF63">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47942">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT (TPR)-LIKE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041908602" evidence="4">
        <location>
            <begin position="25"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="131"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="355"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="48"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="57"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1740456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="635" mass="70916" checksum="D3A05DF19F0164D0" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBU0</accession>
    <name>A0AAD9DBU0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">HVA22/TB2/DP1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_008075</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBU0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004345">
        <property type="entry name" value="TB2_DP1_HVA22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300">
        <property type="entry name" value="HVA22-LIKE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300:SF161">
        <property type="entry name" value="RECEPTOR EXPRESSION-ENHANCING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03134">
        <property type="entry name" value="TB2_DP1_HVA22"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042169613" evidence="8">
        <location>
            <begin position="22"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="223"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="252"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1741597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="372" mass="42034" checksum="D0A03C35CA9345F5" modified="2024-05-29" version="1">MNEAVLSLCCSLGVLLVVSLGYSCIKPNGGQCIKIHLVYFASAICLVAFLPTNIAKYVFTELTVSLVGAMYPVYRATRAVCTPDDDDDKEWLQYWMLGGVLFMITTWVDDVIKQNSVDTIWLGSLLFIFYWLYFPLTCGALVVYEKVTAPYLGPKLKPLQRQMNNFIIYLQQMLSNAFHLYLVWIIFMFLPAGLKRIVAIAIGTVYPTICSITAVATEEIEDDTYWLTYWSVYGCLFLIMDVSEDFLGRIPGFYTLIIFTTIYLMLPMFRGADKIFRKVLVPLAGLHELLVLRDAITIKKQMLKDLDPERAAVVQKSIAKFFDGSTSDSDPSVLKEELMQGWGKIKLPKIKLPFGKAEDGSSDEPNEKTNLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCH5</accession>
    <name>A0AAD9DCH5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007076</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCH5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47661">
        <property type="entry name" value="PHOSPHOGLUCAN PHOSPHATASE LSF1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47661:SF2">
        <property type="entry name" value="PHOSPHOGLUCAN PHOSPHATASE LSF1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042261429" description="PDZ domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="155"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="199" mass="21513" checksum="91FB21E03E51AE44" modified="2024-05-29" version="1">MKSTIAILAAAALAAPSNMFCAGFSSPAVATTQRSPLTSLSMAEEDENFMRWAKQSRSAAQGDNLVELKRPLGLVLDEDDNGNVFVQTVAPRGNAARSGLVKEGDIVTMCSATFGDQMWSCRGVGLTRVLAAIRVRAGPTVSLVFENRQQKKVKGAEVARQAQAAQEARERAQAKRDQLLTELEQDEIKLKKGKFLGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DD90</accession>
    <name>A0AAD9DD90_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Helicase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007973</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DD90"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005114">
        <property type="entry name" value="Helicase_assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03457">
        <property type="entry name" value="HA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase-associated" evidence="2">
        <location>
            <begin position="163"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="580"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="281"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="306"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="580"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="619" mass="68519" checksum="EC064B7446D6EA2E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDC1</accession>
    <name>A0AAD9DDC1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MHD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007427</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDC1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="380" mass="42612" checksum="9CE76D2A38EF53CC" modified="2024-05-29" version="1">MAAQAAFDPFADDWDEHHHHHTQQARSPSPLPPPRLRRLSRYRSCPGTDNHDTLLSKTVDVKKQQPSVGFVTDPNDIFSSTTLYDDDDEFSDVEWPVGGANELKCNNLNDIFLARESNDRDGLVFNVHEEMSIINRSQSKHKHCTVKVCGSVSVESPEQNKPCRLLLNFHDPQGHIDSIASDEYNYVRKDELELEVIVPTEPITQLVQYTGSEQLCPVPMLVKTSVQDCGNHSKLSLQLMVNPRNTSPLVNAAVIVSVPFGYDGERCCVKQSQGDVGRVIDKGVIDSNWSGITRLLSWQLRELHSGAIYEFEAVFPTSSDDDDDDMDDIFTETMSDDSLKFPVLLRYDSAGSLLSGVQINCGRATGHSFKKGFRVYHRET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDE3</accession>
    <name>A0AAD9DDE3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006167</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDE3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041965797" evidence="2">
        <location>
            <begin position="21"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="179" mass="19742" checksum="63F475877751E6E0" modified="2024-05-29" version="1">MKLALTPTFLLVLNLSAAIASHQHLRARQLTNNTDTTNSTVSPAPAPTTTNSTTLTLAPTTNSTTNSTTLSPAPTTSEPTAAPTNEPSAAPTRELTAAPTIWTCPEDVLVPIGTWDDYWWRELPSCVQDAAAVYGYDEKSWDDGDDLCPDFCEEWWKDLIDEQKWASFVFGYDEEIWNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDT5</accession>
    <name>A0AAD9DDT5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Copine</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_007591</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the copine family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDT5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071277">
        <property type="term" value="P:cellular response to calcium ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04047">
        <property type="entry name" value="C2B_Copine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037768">
        <property type="entry name" value="C2B_Copine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045052">
        <property type="entry name" value="Copine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010734">
        <property type="entry name" value="Copine_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10857:SF106">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10857">
        <property type="entry name" value="COPINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07002">
        <property type="entry name" value="Copine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="C2" evidence="3">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="3">
        <location>
            <begin position="116"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="4">
        <location>
            <begin position="337"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1742018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="686" mass="73170" checksum="5CD86E9FF308B823" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEC4</accession>
    <name>A0AAD9DEC4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fatty acid desaturase</fullName>
            <ecNumber evidence="3">1.14.19.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006636</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1743039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEC4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042284">
        <property type="term" value="F:sphingolipid delta-4 desaturase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01060">
        <property type="entry name" value="Membrane-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12879">
        <property type="entry name" value="SPHINGOLIPID DELTA 4 DESATURASE/C-4 HYDROXYLASE PROTEIN DES2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12879:SF8">
        <property type="entry name" value="SPHINGOLIPID DELTA(4)-DESATURASE DES1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fatty acid desaturase" evidence="2">
        <location>
            <begin position="168"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="490" mass="55053" checksum="8F5B2F101883BCCD" modified="2024-05-29" version="1">MVSKMPPTTSLLTASAILHCFFITNTHSYAPSRRAIGSFSRSKHVTTLLRSSPSNTFEEITSSSSDTTPSLSSSHSIEQQQPHNNEVTTPPPSSSTSTTISPTATWHKNRRRQMLQKYGPQLTKLERDSSSNTLALSLLALSNASLFSLAILCGTAQLSVGQIALLAVFPGSMFSLWTLQILHDCLHGSLLNKRQQKFIFGKVKRRTLQDAILFWGSMPSVFGYYLYLRYGHLTHHKSLGDPKAASLEKLFDSSSKEFEDGDVLFVAHRMKLKGKVGPKFQVGGREITMSISKTGFNNWREDKPLWNAVVFATSFMYERFMLMINDVVVAITGRNYFFPNKPKEFHQECAKYCRCAVMVRGLLWKMAGWKSLLFLYLSETLWSIPPHPACAMFVTNHGSNVDDSDDGGGGCIPSSSTYAGRWYSLFTLGTNYHCEHHDFPTIPLHRLGELRKIAPEFYKKGSNDNVFRIMKKAFSKPEFYACMDAGIQHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DET8</accession>
    <name>A0AAD9DET8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Translocator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_006170</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TspO/BZRP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DET8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033013">
        <property type="term" value="P:tetrapyrrole metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd15904">
        <property type="entry name" value="TSPO_MBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.100">
        <property type="entry name" value="TspO/MBR protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038330">
        <property type="entry name" value="TspO/MBR-related_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004307">
        <property type="entry name" value="TspO_MBR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10057">
        <property type="entry name" value="PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10057:SF0">
        <property type="entry name" value="TRANSLOCATOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03073">
        <property type="entry name" value="TspO_MBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042263130" evidence="7">
        <location>
            <begin position="22"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1743549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="306" mass="33082" checksum="A9D926E1D32D7C64" modified="2024-05-29" version="1">MVKLHYGPLAAALLAAPSAHAFAPPSSTVVVNQQQQYSPLSLYKKQECSTIPTTTTTSLRSSSSNINPYTSPELDTSALLKYATAAITELTLFAATFQLLDVAFTNVLDTSVPFPFAFLLFYGCSLKSRVFNPLNNQRPDRSKAVDGEGSSGFKDRVMPSWTPPGVTFPIMWLLIIGPIRAYSASLIVSSTGSFLCLPIMAFMLHLTIGDIWNTINNTEKRYGAAVIGVLCVVLSAANAANQYFAVDPFAGKLLGGTLIWLCTAAALITDTWRLNPSEEGLVPLYPVVGEAETSFMWFGNNDAEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DET9</accession>
    <name>A0AAD9DET9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DET9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="170" mass="18774" checksum="7877E68B0D6E946A" modified="2024-05-29" version="1">MSWTQVYVTGLSRAINPSDEEIEAYLCKRYSLTDAANSVSIGDDNNAATINNDNLMWAGEGSTLIKRDDSGCCRGFAFLTFYSVDGAMIVIDRINNDVSTSESGDDRITLRAELSNPKGGGTNKKKSNKKNNEDNIPDLRLRRQRKLPVRKHPVVTSSDGKRTNLGNKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DF90</accession>
    <name>A0AAD9DF90_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DF90"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="345"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="430" mass="47187" checksum="F290EA2A0A5616E7" modified="2024-05-29" version="1">MSATPVAGRIISRRACALLKKHAPEKFPTPPPKAKSSKTDDTSWPKSVRYTFYTVCAASVPFSIGTAISLSPKLREWMAGDGAPTGDDDASGVSGRKLIRVVRQYWGTEDDIPSVDKPAAGYISPGSRKVWQEDNYSSFLHFLGLDAKTQGTENLGGEVPLSLENEPPANIRHDQELLDKFLSPIANPEGVKTRLTLLPCTDDEDVENAGYDTECTLPANVSLDTLRQMCKGSDAQYTRKVLADSWPDFRLVSSNERLRTGSWSKDCRWVVSFTDDEDSEEVDNSGGNMDDLVADIVVYGDKGVEAMGASESPSDDNNSELLRKSTSIHSSWSYFPELANGAAAGPASSALGASMGAGGRSPSTQTKQQQPSMSLSNADLRIQQLQHQITTLKQELNDPNSFRDRDGMYEELKQAKRELRSLKPWWRKIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFW5</accession>
    <name>A0AAD9DFW5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFW5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="170" mass="19003" checksum="6A345726F3C5FB8A" modified="2024-05-29" version="1">MTIWSPLSIESTVLEISLSSVGIITTKLITNGETIVQATKSAHITPSSSVGELLSVPCSSSLAFLSSLTSKREYSIVIPSVYWPITSMQLQTPSTSTIDRDERQARYLVWSTRERRMRFGVVWMEAKYGVPVKHVWEWDDEEEDGAKDDDEAAEDLDGEGEEDEVKGEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG03</accession>
    <name>A0AAD9DG03_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Zinc metalloprotease (Family M50)</fullName>
            <ecNumber evidence="14">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_004100</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M50B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="14"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DG03"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044838">
        <property type="entry name" value="EGY1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31412">
        <property type="entry name" value="ZINC METALLOPROTEASE EGY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31412:SF0">
        <property type="entry name" value="ZINC METALLOPROTEASE EGY1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="8 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="271"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="385"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="462"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="502"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="552"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M50" evidence="13">
        <location>
            <begin position="330"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1744809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="573" mass="62976" checksum="91B93F96652B99D6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGE5</accession>
    <name>A0AAD9DGE5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vesicle transport protein USE1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_004206</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGE5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="872"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="102"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="193"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="389"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="449"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="691"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="193"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="464"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="697"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="775"/>
            <end position="809"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1744915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="942" mass="107073" checksum="1EB6C314155200D6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGG8</accession>
    <name>A0AAD9DGG8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004039</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGG8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="191" mass="21833" checksum="BA9170966FFA87DE" modified="2024-05-29" version="1">MIGRLSASVQQLNNGRLLHDVSSQVQTTLMSIRGGESKFELETTLDSKYIQSAIGYFNNLRVPAAVLMSIVMKEMYQLQSSPSSSMRKWDREHRVDKSKRWRTLRYTYLLLMVLSFCLEVHTIFVATQVLTQLATAQSVIPHEIDLGDKDMVGGLFKMRATKDAHQSMIDFLISNFEFEYATVRLHFVTGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGS7</accession>
    <name>A0AAD9DGS7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Rieske domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004566</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGS7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042006866" description="Rieske domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="204" mass="21687" checksum="A3F2BACFD668AAA7" modified="2024-05-29" version="1">MKLSSLVLLICAAAVSGFAPALQQQTSSALYMAKGRRGGLTGNGNSKLNKPKSIGGSDSDADSKPKSNWVQTSIPSIKSLPSEKNVVKLVDTQVPSLINKQTNPTGAVSIVNYEDKTYCFSSGCASCQIPLTKGKVLEPSDETNDEARLQCDFCGATYNLRTGAPVQKEGGKLFGFLFSKAEEKELPVYGLGEQGGKVSLMFHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DH49</accession>
    <name>A0AAD9DH49_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_003317</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DH49"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="218"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1745393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="282" mass="32031" checksum="88FB5E497ACC3396" modified="2024-05-29" version="1" fragment="single">QGKARKAAKADKAKEAASVPPNPKDFTEVTLDSWLTCDDESERCKHGCDLSLPKSEHDCRDFAMRYAKDFLIELCRMFGNDQLLKNASTSNDLVGQCVQQGKPFVAAIDNMEDKYPDIFESLSKLKWAISFYHSRGTQDVIDGNMKRAHHAAICATLMNGYLSDLSDVSTMKLYDIMQANDKMILTYFRKRISCSCLDEKRKEYKGVKKTGKCCNDQCPLPGRVAERSSLLYCTACKFVQYCSAECQKVNWKYHKHQCTSIAKLNSIDYEYVQNIAQVNLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHV1</accession>
    <name>A0AAD9DHV1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pre-mRNA-processing-splicing factor 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002917</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHV1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097157">
        <property type="term" value="F:pre-mRNA intronic binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030619">
        <property type="term" value="F:U1 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030620">
        <property type="term" value="F:U2 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030623">
        <property type="term" value="F:U5 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000244">
        <property type="term" value="P:spliceosomal tri-snRNP complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012592">
        <property type="entry name" value="PROCN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027652">
        <property type="entry name" value="PRP8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11140">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR PRP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11140:SF0">
        <property type="entry name" value="PRE-MRNA-PROCESSING-SPLICING FACTOR 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08083">
        <property type="entry name" value="PROCN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PROCN" evidence="2">
        <location>
            <begin position="321"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="438" mass="49500" checksum="DE0E48E1D5849DEF" modified="2024-05-29" version="1">MEFGNESYGGDDSDDESDDGLDEVERFVASWLYENKPLAEPVDYDEFEDSDDEDEEGEDRCAGYRVPGGRYTNGPSYHTWRLPTPVMSCLYRLAGPLVSTHLLDPNHRHLFHLPEFLTAKALNVAIPGGPKFEPLYRDVQEKEEEDWNEFNDVNKIIIRHPIRSEYRIAFPHVYNSRPRKVVVGGGGYHHPQLCYVGEDDEDNDEAMGGAGAGCFQTFSSAINPILSVVQSEYKLESGRNDAVMGEEDEFNEDMMLPLVGETDEDYDGDEEDDVWLMHDDMDDIEDDFAAPDGALWGPDDEVQTTTGLRPLLSSVPLSTSRTGPGIALYFAPRPFHMRSGRTRRTIDVPLIGHWARERVSREMNYPTKVRVSYQKLLKNWVLNQLHAQPNVKKNKKVLFKSLKATKFFNALSLIGLKLGCKCVVKDTICSIYLSIGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DI14</accession>
    <name>A0AAD9DI14_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NAD(P)/FAD-dependent oxidoreductase</fullName>
            <ecNumber evidence="4">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_001935</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DI14"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF309">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="3">
        <location>
            <begin position="10"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1747972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="453" mass="50168" checksum="19D0966EEAA3DA02" modified="2024-05-29" version="1">MPRFHRNENPVIIAGAGPCGLVAALTLEKAGIPYVIYERTTTEKLCSNAGSGIDMAPTAIKILDDYLGLAGKNWMAPYEIMYISDMKGKQIALWDMPSLKLKKDSERLSFGTANRARLQHNLLDALNLKDVNGDIKNDDDRLICSTSVVGYQNLDGLVRVELNDGTKVDALALLACDGIHSAIRKHMHKDVDDSLNYCGQECWWGKTTVKPGSELSEELKRLPSTSMVAIGTNEMPGAFFSDEVAPNEHAWGYVLANKTPPNANATNDLTRRGGSVLTTEEKKREIDEVIADRSKVLQLMLQEPSADEITRAGFFDRKNLDLSYINGRVALLGDAAHPQSPMMGQGANMAIADGYVAASRLLAALKGTNDSTVEQALLDYDCKLRRKENNIVIKKARKYGNWAASKTRFRCFCMKMMCKYMPPSMLVTEMMSGDKSNKKFVHAMRKDLQLEVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DI33</accession>
    <name>A0AAD9DI33_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Upf1-like family helicase</fullName>
            <ecNumber evidence="2">3.6.4.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DI33"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043186">
        <property type="term" value="C:P granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035194">
        <property type="term" value="P:regulatory ncRNA-mediated post-transcriptional gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF322">
        <property type="entry name" value="HELICASE MOV-10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="1">
        <location>
            <begin position="2"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="304" mass="34614" checksum="9434319B261F5447" modified="2024-05-29" version="1">MMPSALFYYDRLRSAKNLGLDSLSYWIERLRSVEALTNRVEMAVEAPASCEDNMNIYRQVHRQNKWPIHFRAVKGKDTSVSLDTFTGTDSWQNSEEADTAVEIVDALIQSGVAPIKIGVMSPFRGQVVAIRKRCRAKHYHDVNVGTIENFQGVEQDVIILSLTRSNPAFVENDVKRRMGLFGMPKQANVALTRAENLFIVIGNPESMWEDQLWRQWLLFCFRNGLWYGEGLEEWDSVKSGFNDANFVEMLEQVDDESNDTDSVVVSTMEKIHRVHSTDECKSEEIGLNVQKASAEGMLARICHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DID8</accession>
    <name>A0AAD9DID8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Lipase class 3 family protein</fullName>
            <ecNumber evidence="7">3.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_000915</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15760">
        <property type="entry name" value="FYVE_scVPS27p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46023:SF6">
        <property type="entry name" value="LIPASE CLASS 3 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46023">
        <property type="entry name" value="LIPASE CLASS 3 PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="6">
        <location>
            <begin position="429"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="6">
        <location>
            <begin position="1269"/>
            <end position="1333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="40"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="118"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="720"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1066"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="125"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="146"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="724"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1083"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1132"/>
            <end position="1143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1748976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1379" mass="152567" checksum="07C98B20CC0EA832" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DII5</accession>
    <name>A0AAD9DII5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">VTT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_000406</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DII5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015414">
        <property type="entry name" value="TMEM64"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="VTT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12677">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP38-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12677:SF59">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP38-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="VTT_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042106135" description="VTT domain-containing protein" evidence="7">
        <location>
            <begin position="24"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="VTT" evidence="8">
        <location>
            <begin position="152"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1748467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="316" mass="33804" checksum="922F17A74EDD9E37" modified="2024-05-29" version="1">MMCSRSLHLAVACLLCCIGSSIGFAPVRTVVGARSTNNQQLESLYRSNQVSGPRQSTLLYSGNPSKPLTSKVNKNKNNIAALAIVLAGIGLTAYPSPCFAASSILSNIPSPSKFKEAIVSVLDGMSQSGTKGMVAYVLSFTAWTMTVGVTTPVETAAGMAFPLKQSIPLSALGKIGGAFCQYVLAKYLFSDYAREKMKDNEWMGKIDKSFKSHPFGVALIWRFSPLPEFVKNVGPSLVKTLKTRYQLLAILAHGLPFTILWSFMGAETAAVARGGEASVLLKRLVAIISSVGLFVSPTLFGMWLKGLGDDTKSESQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJT2</accession>
    <name>A0AAD9DJT2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000274</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJT2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="422"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="615" mass="70901" checksum="95F787FDCC637A51" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2020-12-02" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6T5SPR4</accession>
    <name>A0A6T5SPR4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">V-type proton ATPase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_010804</name>
        <name evidence="6" type="ORF">SMAR1039_LOCUS551</name>
        <name evidence="7" type="ORF">SMAR1039_LOCUS552</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">FE7</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the V-ATPase V0D/AC39 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="HBGM01000790">
        <property type="protein sequence ID" value="CAD9313427.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="HBGM01000791">
        <property type="protein sequence ID" value="CAD9313428.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6T5SPR4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.50">
        <property type="entry name" value="ATP synthase (C/AC39) subunit, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1690.10">
        <property type="entry name" value="V-type ATP synthase subunit C domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036079">
        <property type="entry name" value="ATPase_csu/dsu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002843">
        <property type="entry name" value="ATPase_V0-cplx_csu/dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016727">
        <property type="entry name" value="ATPase_V0-cplx_dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035067">
        <property type="entry name" value="V-type_ATPase_csu/dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044911">
        <property type="entry name" value="V-type_ATPase_csu/dsu_dom_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11028">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT AC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01992">
        <property type="entry name" value="vATP-synt_AC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018497">
        <property type="entry name" value="V-ATP_synth_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103486">
        <property type="entry name" value="V-type ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR018497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CAD9313427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CAD9313428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1738774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="392" mass="44175" checksum="DE8B0ACAE4A76809" modified="2020-12-02" version="1">MATPAPKSGPGNLATFNILHGFPEALVRGMRSSFLADADYHHLTQCETLDDVRLNLSETDYMDALADMGTLIPTGLQKAAVEKLVTEFKYLRTQAIEPLSTFLDFITYEYMIENVMLLLKGTLSGRDINELIAQCHPLGMFKESTMRSIPTFESTPRGYQDLYQTVLVDTPVGPYFAQFLQESSDRSEVSNVLEEVEIEIIKSSLIKYWIEDFAKFVDALGGETAVIMGDLLKVRADTNAINITLNSFGTPLNEPAMRASDRKRLYPAVGHLYPAGTSMLADVGDEDELGRVLELFPMYSSIWNVHAAGSDGKSIDDAFYERDVQMLELAFEGQMHYASFYAYVKLKEQEIRNLVWISECILQQQKEEIHKFVPVFSFNAPWRAGSNKHGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1GXM8</accession>
    <name>A0A8K1GXM8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Photosystem I reaction center subunit XI</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">PSI subunit V</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">PSI-L</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">psaL</name>
        <name evidence="10" type="ORF">QTG54_017186</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="11"/>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2021" name="Front. Plant Sci." volume="0" first="0" last="0">
            <title>Chloroplast Genomes for Five Skeletonema Species: Comparative and Phylogenetic Analysis.</title>
            <authorList>
                <person name="Liu S."/>
                <person name="Xu Q."/>
                <person name="Liu K."/>
                <person name="Zhao Y."/>
                <person name="Chen N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CNS00100</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Plastid</location>
            <location evidence="8">Chloroplast thylakoid membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the PsaL family.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MW679506">
        <property type="protein sequence ID" value="UAM91389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_010200899.1">
        <property type="nucleotide sequence ID" value="NC_058701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1GXM8"/>
    <dbReference type="GeneID" id="68638026"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009538">
        <property type="term" value="C:photosystem I reaction center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1240.10">
        <property type="entry name" value="Photosystem I PsaL, reaction centre subunit XI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00447">
        <property type="entry name" value="PSI_PsaL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003757">
        <property type="entry name" value="PSI_PsaL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036592">
        <property type="entry name" value="PSI_PsaL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022980">
        <property type="entry name" value="PSI_suXI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34803">
        <property type="entry name" value="PHOTOSYSTEM I REACTION CENTER SUBUNIT XI, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34803:SF2">
        <property type="entry name" value="PHOTOSYSTEM I REACTION CENTER SUBUNIT XI, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02605">
        <property type="entry name" value="PsaL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81568">
        <property type="entry name" value="Photosystem I reaction center subunit XI, PsaL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="11" id="KW-0934">Plastid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="75"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Photosystem I PsaL reaction centre subunit XI" evidence="9">
        <location>
            <begin position="5"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1732143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="UAM91389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="148" mass="15710" checksum="2AF65DA08F0BF173" modified="2022-08-03" version="1">MANFIKPYNDDPFVGHLATPITSSSLTRALLKNLPAYRFGLTPLLRGLEIGLAHGYFLIGPFAKLGPLRNSDIGLLAGFLSTVGLILILTLGLTIYGAASFGQEKSTGTELQTKKSWDEFKGGFFVGACGSAGFAFICLSSIPTFTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1H0P7</accession>
    <name>A0A8K1H0P7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Photosystem I assembly protein Ycf3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">ycf3</name>
        <name evidence="8" type="ORF">QTG54_017216</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="9"/>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2021" name="Front. Plant Sci." volume="0" first="0" last="0">
            <title>Chloroplast Genomes for Five Skeletonema Species: Comparative and Phylogenetic Analysis.</title>
            <authorList>
                <person name="Liu S."/>
                <person name="Xu Q."/>
                <person name="Liu K."/>
                <person name="Zhao Y."/>
                <person name="Chen N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CNS00100</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Seems to be required for the assembly of the photosystem I complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Plastid</location>
            <location evidence="6">Chloroplast thylakoid membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the Ycf3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MW679506">
        <property type="protein sequence ID" value="UAM91416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_010200929.1">
        <property type="nucleotide sequence ID" value="NC_058701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1H0P7"/>
    <dbReference type="GeneID" id="68638066"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00439">
        <property type="entry name" value="Ycf3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022818">
        <property type="entry name" value="PSI_Ycf3_assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051685">
        <property type="entry name" value="Ycf3/AcsC/BcsC/TPR_MFPF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002725">
        <property type="entry name" value="PRK02603.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44943">
        <property type="entry name" value="CELLULOSE SYNTHASE OPERON PROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44943:SF8">
        <property type="entry name" value="TPR REPEAT-CONTAINING PROTEIN MJ0263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="9" id="KW-0934">Plastid</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="4 6 7" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="31"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR 1" evidence="6">
        <location>
            <begin position="31"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="68"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR 2" evidence="6">
        <location>
            <begin position="68"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1732173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="UAM91416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="184" mass="21330" checksum="6D4DA8AF371C91A6" modified="2022-08-03" version="1">MGVRNFIDRVFTVISDLILKLLPASKQEKQAFAYYKAGMAAQAEGDYAEALENYYESLYLDEDQYDRSYTLYNIGLIYAKNENYPRALEYYHQAVSLNSNLPQALNNIAAIYHRQGLLALEMASQDYDSTMEISEEYEYIELAKGLFDKAAEYWYQALKLAPDNYPRARNWLRITGRAKSLDSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRJ6</accession>
    <name>A0AAD8XRJ6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016799</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000065">
        <property type="protein sequence ID" value="KAK1732516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRJ6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042003958" evidence="2">
        <location>
            <begin position="19"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="270" mass="27359" checksum="2C8C06593BB958AA" modified="2024-05-29" version="1">MKIQILFLSLLATATANARHEHEPKSLRGGNGDEHDLALALALESRQINHIIPHGKSASIQCGSGSQCCVTGNFKSLNNMGIMTNEGSCQGFSFTNVSLSNCQSNTCFASCDGGCNVKVQAGGAGRGGSAGGRGRGGGAAGGKRGRSASGQGHTRRVDRIIPQGRSAAFQCGSGSQCCVTGNFESLNNMGIMTNEGSCQGYSMTKGSLSNCQSNSCSVSCDGGCDVLEAERGGSAGIHVHAGGRNDGGGKGGRSRVGPGNNPHDFANKIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XST3</accession>
    <name>A0AAD8XST3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SufE-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016563</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000058">
        <property type="protein sequence ID" value="KAK1732760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XST3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.90">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002634">
        <property type="entry name" value="BolA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036065">
        <property type="entry name" value="BolA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003808">
        <property type="entry name" value="Fe-S_metab-assoc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46230:SF3">
        <property type="entry name" value="SUFE-LIKE PROTEIN 1, CHLOROPLASTIC_MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01722">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02657">
        <property type="entry name" value="SufE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82657">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82649">
        <property type="entry name" value="SufE/NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041907622" evidence="1">
        <location>
            <begin position="20"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="Fe-S metabolism associated" evidence="2">
        <location>
            <begin position="81"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="334" mass="35831" checksum="E2C25D9658678C53" modified="2024-05-29" version="1">MRRPSKPLLIAGIPIAGLALSSYNGGSTVSAWSPAPHTTTATSRRSHKQSSSSSVILHSAIEDELDLSSLHLTPQLEMMVTAFSSIPDEKTRHKQLLYMASKLPAVTDDVRISENKVPGCLSTVHVDCTLEPKEGDDDQETMVVNYFGDSDGLLTKGLLALLIRGLNGATPEEIQNVDPQFIQAAKISQTLTPGRNNGFLNMLAVMKKKALDAAEGGAAADVDADGGAEEQSAIVTSFEEIDGKPMYNIIMTTLITILKPTSITLTDNSSQHAGHAGSKGWEESGESHFALEIVAEAFEGLSLVKRHQLIYMLLGETMQKIHALEIKAKSPAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XT29</accession>
    <name>A0AAD8XT29_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016296</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000055">
        <property type="protein sequence ID" value="KAK1732965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XT29"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="590"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="590"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="600"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="688" mass="76842" checksum="CC0D51CA10178A4B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTF0</accession>
    <name>A0AAD8XTF0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_015809</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000048">
        <property type="protein sequence ID" value="KAK1733521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTF0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023779">
        <property type="entry name" value="Chromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051219">
        <property type="entry name" value="Heterochromatin_chromo-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22812">
        <property type="entry name" value="CHROMOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00598">
        <property type="entry name" value="CHROMO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="4">
        <location>
            <begin position="435"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="565"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="599"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="627"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1733521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="636" mass="71108" checksum="4ECC155E0C420847" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTG9</accession>
    <name>A0AAD8XTG9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Peptide deformylase</fullName>
            <ecNumber evidence="2 3">3.5.1.88</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_016243</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Removes the formyl group from the N-terminal Met of newly synthesized proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>N-terminal N-formyl-L-methionyl-[peptide] + H2O = N-terminal L-methionyl-[peptide] + formate</text>
            <dbReference type="Rhea" id="RHEA:24420"/>
            <dbReference type="Rhea" id="RHEA-COMP:10639"/>
            <dbReference type="Rhea" id="RHEA-COMP:10640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:49298"/>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
            <dbReference type="EC" id="3.5.1.88"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the polypeptide deformylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.88" evidence="2 3"/>
    <dbReference type="EMBL" id="JATAAI010000054">
        <property type="protein sequence ID" value="KAK1733105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTG9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042586">
        <property type="term" value="F:peptide deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.45.10">
        <property type="entry name" value="Peptide deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00163">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023635">
        <property type="entry name" value="Peptide_deformylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036821">
        <property type="entry name" value="Peptide_deformylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458">
        <property type="entry name" value="PEPTIDE DEFORMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458:SF22">
        <property type="entry name" value="PEPTIDE DEFORMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01327">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01576">
        <property type="entry name" value="PDEFORMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56420">
        <property type="entry name" value="Peptide deformylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1733105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="608" mass="67400" checksum="F00A5032EC365FA6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUQ6</accession>
    <name>A0AAD8XUQ6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUQ6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21301">
        <property type="entry name" value="REVERSE TRANSCRIPTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21301:SF10">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="320" mass="37036" checksum="843F744AC66FDF9D" modified="2024-05-29" version="1">MERFDYNADCLIEAIGIVLRSNIIKFGDIFAVQKKGVAMGICPAPSIAIIFFAIHEEFLMSKWSGSIMFYLRFIDDVFGIWLSNPNYVADNRQWNNFQDDVNDFHGLPWEFIPRSTTVQFMDLTVSIEGERLSTDLFEKPMALYLYIPPHSTHPPGGINGLITGQMLRIFTLCSDPERIKVHTLNFLHRLQARGYDKKDLIPLLDRATKNARKYLQRSDEQKQQISKERKDSMARCIRLHRLFNPYDPSGSTIQLLFKECILTPEGRTPLYELENLDHSKIPIDRLMLCNHRAPNLGNFLSYRDIEKRSGAKVSAYLKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV17</accession>
    <name>A0AAD8XV17_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1734032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV17"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="272" mass="30540" checksum="06635ABBDB36D2A2" modified="2024-05-29" version="1">MENCTYFFVEHDITDRQGWDKWRTSWYDIFGAEDMTVDKARSYPEWEGNECVLAIPTSDDKMAIALWKMRSGTSKDEFQAFIDRFVCGYANNKVFQVEHALGAKKLDARGYFSDLINAAQGRHSPGYLDAPKVWLTHHCILDREGFSALNASIADKINKTCTTPSDCQTVFPTGHKCCLALFFTGNDMVCFESTAEGVTYDDVRKAEDEFTRGMSRNNVYELDTAKGINAFHLSEDNWSQDAMTWANTTVKTAPVDSTTATMTTPVGIEAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVD8</accession>
    <name>A0AAD8XVD8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_014822</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000038">
        <property type="protein sequence ID" value="KAK1734574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVD8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="7">
        <location>
            <begin position="16"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="283"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="292"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1734574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="306" mass="34596" checksum="982181BDC0F2BC5E" modified="2024-05-29" version="1">MMSTDDEAAGNMMMFCASCGIAENDDVKLKKCACNLVRYCSVTCQRDHRSQHKKACKKRVAELRDELLFTQPESSHLGDCQICFLPLSIDLRKSTLMSCCSKTVCCGCEMASILHQKVNSGNPETKCPFCRKPPPCDLNGEVELNTMKRIEANDPAATRQKGMKCYNKGEYESAFKYLTKAAELGDYEAHYHLSRMYRDGRGVEQDSKKEKYHLQEAAIGGHPSARYTLGLYEARQFRFDRATKHWIISANLGCDESMDMIREFYSKGAVSKEDFAAALRAHQASVDATKSPQRERADEVNRMTNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVJ3</accession>
    <name>A0AAD8XVJ3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">phytol kinase</fullName>
            <ecNumber evidence="16">2.7.1.182</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">QTG54_014990</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>phytol + CTP = phytyl phosphate + CDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:38055"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17327"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:58069"/>
            <dbReference type="ChEBI" id="CHEBI:75483"/>
            <dbReference type="EC" id="2.7.1.182"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="15">Cofactor biosynthesis; tocopherol biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the polyprenol kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.182" evidence="16"/>
    <dbReference type="EMBL" id="JATAAI010000040">
        <property type="protein sequence ID" value="KAK1734223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVJ3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010276">
        <property type="term" value="F:phytol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039606">
        <property type="entry name" value="Phytol/farnesol_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32523:SF8">
        <property type="entry name" value="DOLICHOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32523">
        <property type="entry name" value="PHYTOL KINASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 18" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="20">
        <location>
            <begin position="215"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="19">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00024015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00039024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAK1734223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="277" mass="31525" checksum="162DA495C16C8DBB" modified="2024-05-29" version="1">MGRKRNQGKARKAAKAKAKEAEEERGQMTNERQQSLAAQIQLMQIGGGDTTECWHGLDRRFEKVDYVMFVDAFKDAFSASVSVTQGADISICLIEAEDATKDEFAEVWNDSAKMESAMSILLWSGTQQILEGDYNVARLSALFSRFFEQFISAALYQSQAIMNWTKIDVISNGRGSDIHSLVKFFRKRIPCTCLDEKYDEVKYITKMGICYNPDCRLNPSGEVERSKTMYCSRCRSVTYCSHECQKADWSQHKEICYHQASIIAEFEAKKRSIDNAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWN8</accession>
    <name>A0AAD8XWN8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Fucoxanthin-chlorophyll a-c binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">QTG54_014143</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated. Energy is transferred from the carotenoid and chlorophyll C (or B) to chlorophyll A and the photosynthetic reaction centers where it is used to synthesize ATP and reducing power.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast thylakoid membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fucoxanthin chlorophyll protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWN8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030076">
        <property type="term" value="C:light-harvesting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3460.10:FF:000011">
        <property type="entry name" value="Fucoxanthin chlorophyll a/c protein 8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 15" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="5" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="10" id="KW-0157">Chromophore</keyword>
    <keyword evidence="13" id="KW-0437">Light-harvesting polypeptide</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="14" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041969157" evidence="16">
        <location>
            <begin position="16"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1735077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="410" mass="43399" checksum="86B59B6A20EB3113" modified="2024-05-29" version="1">MKSAIIAALIGSAAAFAPAQTGKATTALNAFESELGAQPPLGFFDPLGLLDDADQERFDRLRYVELKHGRISQLAFLGQITTRAGVRLPGDIDYSGTSFADIGEGWSGSLQVPVAGALQILAFVGFLELGVMKDIEGTGNEHVGDFRNGALDFGWDTFDEETKLSKRAIELNNGRAAMMGILGLMVHEQLGGSLPVVGEITKSTTSSISNMKSAIIAALIGSAAAFAPAQTGKATTALNAFESELGAQPPLGFFDPLGLLDDADQERFDRLRYVELKHGRISQLAFLGQITTRAGVRLPGDIDYSGTSFADIGEGWSGSLQVPVAGALQILAFVGFLELGVMKDIEGTGNEHVGDFRNGALDFGWDTFDEETKLSKRAIELNNGRAAMMGILGLMVHEQLGGSLPVVGEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWR3</accession>
    <name>A0AAD8XWR3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ethylbenzene dehydrogenase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014332</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWR3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36044">
        <property type="entry name" value="HEME BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36044:SF1">
        <property type="entry name" value="HEME BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="354" mass="38338" checksum="3142E410808CD271" modified="2024-05-29" version="1">MIFPKTNSAAFSLALSISAFKTLPAIVAEDSCTSIDYITCIKTASPPTLDASDISDWDGVEAFESPLTGALTSKMYTAGNMKIQCVYDATDIYFLYQIPGKYMFDITDNKKCASVASMFQMGEKATFFNMGGCPLSEAVNCDAVPEGCAPYAVDIGAHWELKTTERGVMYGPNEATGNDLIANKDDEFAVGPYCRVDDNFGTSPGNEWSGAWDFTGNATDGAEGYYIFETSRSLTTPSPETDVQLTPGTEVNFGVSFWDPFETAAGWTDAGHVVTGCSEDWVGLRLVDENGDATPVFDDVGGEEESAEPMPMESGTDGMETASSSTPAPQRRSLYHCRRCIYFRCIYLCCMCCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXL1</accession>
    <name>A0AAD8XXL1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADPH oxidase</fullName>
            <ecNumber evidence="4">1.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_013462</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.3.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXL1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF153">
        <property type="entry name" value="SUPEROXIDE-GENERATING NADPH OXIDASE HEAVY CHAIN SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="609"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1735756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="746" mass="85244" checksum="6269C66FFDDBDE94" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXZ5</accession>
    <name>A0AAD8XXZ5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_013400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXZ5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B lectin" evidence="3">
        <location>
            <begin position="281"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="450"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1735694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="644" mass="69703" checksum="3AECC3385B65190F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XY34</accession>
    <name>A0AAD8XY34_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Prolyl 4-hydroxylase alpha subunit-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_014035</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XY34"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF236">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041941556" evidence="6">
        <location>
            <begin position="27"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="7">
        <location>
            <begin position="164"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1735421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="306" mass="33441" checksum="A77E607B1BEDAE75" modified="2024-05-29" version="1">MMTTRRHILCVWLFINSSIFIKRAAAFSTAAKQQAVIPPGILGPPEPLKSLQVGQTLNAFRLVVDDDDDRVDFSIERVANSPHIFLLRNFLTSSECNQIQALAEEGGMKTAETVTKGDTSSRKNCSVAWIPSSGPDGSSLVSGLVASTVNIFLSDVVKSRPSAGVENMQILKYGVGGEFVHHQDGDARVFTVIYYINGVGGTWFPLADRNDGEIPKNKAGVLELVENLEPGKHGIFLKGDSSNSAQEGNNNKHTVLVNKGDAVAFYNYRDEGSAQLDWAALHCGSPTDETKWIANHWYRLNELANY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZE7</accession>
    <name>A0AAD8XZE7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Style cell-cycle inhibitor 1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZE7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044688">
        <property type="entry name" value="SCI-1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34117">
        <property type="entry name" value="STYLE CELL-CYCLE INHIBITOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34117:SF1">
        <property type="entry name" value="STYLE CELL-CYCLE INHIBITOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="460" mass="53571" checksum="DD1FB70E444396A9" modified="2024-05-29" version="1">MGSSSDGRRRHRSKDDRRDRESSSRRHEEEGRGSSGGNKLTEEERRLYDKARAYVEQKDKGKQSHKGRKKKSRDKYNSSDDDDDSNASSRRDRKRHRSSSHRERKKHHKRSRSSRDGDDRHEKHHKKKSSKHRHRDDDDDDEKHNKHSSSKRHKSSKHHDNSFRQKATKHSNTSKLVSLGEIVSEPPQEPLDTDTNYFSHNSHLRLYLFRNYGIYFEDLTSEESHDAFKEFVSKYNDGKLDAAYYDTTKGKLPQEALDQCQRTQHKWNFKTNKVELQSLKIVRDGVKKQTEYDADNNGKGGMMPRTQATAAVAARPKSDQSDEHKNRLSYDERRRSDKRHREKIKAGNEEIYGIGKADPGRERQIEKKREQANKIHGAARSQEVELDDKAIYGGEGGGDISYEAALAREKKYRERKEAAKHERTSELLKKEDDKQKKMLEMLGFSGLKPGEKIKIAPRQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZM7</accession>
    <name>A0AAD8XZM7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012968</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZM7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052585">
        <property type="entry name" value="Lipid_raft_assoc_Zn_ADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43482">
        <property type="entry name" value="PROTEIN AST1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43482:SF1">
        <property type="entry name" value="PROTEIN AST1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="2">
        <location>
            <begin position="152"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="494" mass="53795" checksum="733AE2247D791906" modified="2024-05-29" version="1">MVATSKKASIKGALGRRRQKTAPPKTQGGDDTAELDRLVKEKIVSANNNKKWLKVKTALEETPRASNSSTRNWQETRGDECNDDGYSYSDESRDESALEHKSFDSCGSSTMGESLGHCGSSWDDEDQQENAFFEKSVKVETHQAVVKVLEHGNTQMLVLEANPTKGIPKCSEPDDVVIKVDCSTITLQDCMIRRGKWNDMQSLPFIPGSDIVGTITELGSPDLESRFRVGNLVAAVVPSGGNAKYAKVKAKELLLVPTGVDPVTALCISSTYVPAKQSLEAARSSGTPLTGANVLVIGANGPTALATIDLALLEGANVYATADKRHHDHLLSLGVKQCFPVNPLKWLPRLECKMDVVLDSVCLDGYESSAKALGPRGKLICTGMSATFTQGRIEGPLGIGDLRLLTASYQKARVKYRMHNACYYDKVESFKDQKAIYAQYFKYLCHIQAKGHFKPVVAARASLTMVSSLQKAIERGDTPYGVCVATPWLTREDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y063</accession>
    <name>A0AAD8Y063_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012538</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y063"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="337" mass="38360" checksum="5213CC7E2E6DAD12" modified="2024-05-29" version="1">MTQSCHIISRGILPSINLEHHNDKNFELAMNNAAPLSSPPVPEVEQPPEKKAKTAVAHLLKTVGKDLVKEDEATEFVGLLDHQQLNMLFAKMIERKQKESNDKDVVSYQHVRNRRRINYLKIPSSRVDALESFNKNNTWINRAVEISCATTGNKEKDKTNEQASAKRIIKQCFKVYPEASKVAIEECKKGREELKILPQDRKMDGLKIATMFKAAQITSLQKRRYLLRHLRHHFGKHAFDIEQNIQKFWDGHSEPHPDIAIWNATVDGVACRGPRKSKEEIAKEAELKLQRKMERQRQKEDGWNVVMTGETSGQPQTASHPPTASHPPTASYPPTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0I0</accession>
    <name>A0AAD8Y0I0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glutathione transferase</fullName>
            <ecNumber evidence="3">2.5.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_012429</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>RX + glutathione = an S-substituted glutathione + a halide anion + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16042"/>
            <dbReference type="ChEBI" id="CHEBI:17792"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GST superfamily. Mu family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0I0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF222">
        <property type="entry name" value="GLUTATHIONE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="6">
        <location>
            <begin position="19"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1736984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="248" mass="27869" checksum="D2ECE2B650B7C7B4" modified="2024-05-29" version="1">MTVLSITKSEDVPLAPIDGKPTLVYWNSAGWSNPIRLALTVANVDFVDARIEAGDPSDSASFKKAWMDAKHVLGSTGILEFPNLPYYMEGDSVKLVQSEAIVRHVARKYNLYPTSMPEHRFMMLSEEIKDYDGYFILQSYVGGPDVISQFIKEGVPNKLAIWGKIAHDGNALIDGPDGKINILDIKLYCFLRKVKFSQEELNIKPSAQEGWVDAYMKRVEDVPQVKAYLDSDYLHRPLNNPHATFASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y103</accession>
    <name>A0AAD8Y103_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011902</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y103"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031568">
        <property type="entry name" value="Pet117"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15786">
        <property type="entry name" value="PET117"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="75" mass="8718" checksum="C873E36983F837E5" modified="2024-05-29" version="1">MNKPRIRGPAIVLGLTTSITAYAIFYSHFQQVRDKKVMREGVARDKERIRLKRKEQQLMQQQQREGVSESGDSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y353</accession>
    <name>A0AAD8Y353_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y353"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042180031" evidence="1">
        <location>
            <begin position="20"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="568" mass="60034" checksum="5178D7042B5C3088" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4K9</accession>
    <name>A0AAD8Y4K9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4K9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="184"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="302" mass="35425" checksum="FDCCEB584B209EBF" modified="2024-05-29" version="1">MALAYPIRNVKDLAHAFAAKDEFISALSYYLYSNTDNYIMNPLDEYYVAPYCFMCTKNNPKSDKAGFLVFSSMAPFVQKREHDEAFSLIKRQGYHKTPFIGTIEKFQELLKLKEKDIYTFTSDGCVPTAEDVSQELEDVAIRVVCDLMRWRYPYSWRDKREEVASYFGPVLDLAEYDGRKKNKQQQLIQHQDQNHQQLQYQQQEQQQQQENFYDAKECAAEEEKKETTALDYLPLPPVHTPTQDKKSGGFFERNADIFNNPFISRYNHNDLENEEDDDGNTFISTNNTVYDEDDIFHDIYGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5R0</accession>
    <name>A0AAD8Y5R0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-CH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_008947</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1739997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5R0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-CH-type" evidence="4">
        <location>
            <begin position="13"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1739997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="461" mass="51353" checksum="1898CBC7A4BC861F" modified="2024-05-29" version="1">MTKVEKDSTAATIEFPDDVSCWLCLEEGPDESGKPLVRDCSCRGSSGVAHIACIIGYAESESRQIYEREGPAKCIIPFHDCPSCKQPYQNDVRKDLAKAAVKFVESEFWGDSFRSFPHEFLRMNILMNRVDTLQNEEDAADANEIAEKFISACDRSKMKLDVAGEGLRLREESRVFKLLAANGYATIGSFYRKIEGGQMRAIEFFEKARDVFKTMHTTDAEAELGLTAIGKIISDINSELSGNVGNAKTATHGVKFLRQKYLKGINLFGEKDPMVIGMGVELVYGLKVELRAIEAERFARKLVEISRRTHGADHGSTKNALLALQDITTRQIAIRLPDFSAAFQALRYENDGEKCVVQGPLAFPRQTEEEHECVFDSIDIILVPGTPVVCHSLQKAAHLNGKIGEVRDVDMKEKEDGSKYFDKDTDRCVVHFEDKSLKPVRVKAANLRVVFDLPAATAVDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5Y8</accession>
    <name>A0AAD8Y5Y8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009284</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5Y8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="349" mass="36532" checksum="DB33EB5DA1D1F6C3" modified="2024-05-29" version="1">MTAPSTLSHKKRKLSATGLSLSSSVSKNGNKNKKLNLPQVQAGDAKTSDSAGMAIASNFTSSVHKVMMDISSNRDLPLEEFHFDTGGSVLVAAADGDKYISTNPGVLRLIKTLLTAENEDQIDKALEDDFTAVAAKLPKGDCGGGCGAGFQVYLKGELVLTCGGGGGGGYTSGHEKALERGGGGGASIFIPGDESAHVGGGHGLANGTVESKHDADHDATLFLDKLQKLRDLLSEAHTSDICVLGGGGGGGGETEILRLRSQGEKTEGSGYGFGFHIGSMSSGRPKRRIKTPNRLTVSSFSNVKDYDTKPSTITKNKNSNDLNLPEHLLKEDWAIKMVEYKGKYASGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7J0</accession>
    <name>A0AAD8Y7J0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008562</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7J0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="337"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="366"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="404"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="673"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="734"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="785"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="832"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="970" mass="106797" checksum="C789E6800118B712" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7M0</accession>
    <name>A0AAD8Y7M0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein LOW PSII ACCUMULATION 1-like protein (DUF3493)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008655</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7M0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021883">
        <property type="entry name" value="LPA1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35498:SF1">
        <property type="entry name" value="LOW PSII ACCUMULATION-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35498">
        <property type="entry name" value="PROTEIN LOW PSII ACCUMULATION 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11998">
        <property type="entry name" value="DUF3493"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041996985" evidence="2">
        <location>
            <begin position="18"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="345" mass="37333" checksum="FB90E2D54667C6C6" modified="2024-05-29" version="1">MKTSTLILASFLGTAAAFAPPTSSHHMSKSVQTQQRQILTQLYETDETKPKKSSTGIDRNVSNKLLAETIAPFRGLRLFFYAAFASGAFVGGLITASGVAAALSGVRTDVDLNTEYLNLGIDFGAVALFAVLAKFDLNKGEELNAAVEAKVERKKAMKKITSAMKEREQQLADLNINVRVTEEGDTKTATMGTMQSMAKQHIIMVAGPGRAIRDALRGAQLNKVNFAMTNILVVPYETGLDEAARASKPSGGFGDRPTYETQAYVAEAVGEGWESFIEAEMETAAEQAGEKVREEGIALVIANDGKVLRRGVGRVPWRQMVDELEESVTGEKKETSIPFLEFLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y884</accession>
    <name>A0AAD8Y884_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ribosomal RNA large subunit methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008877</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y884"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11572">
        <property type="entry name" value="RlmI_M_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.80">
        <property type="entry name" value="RNA methyltransferase domain (HRMD) like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42873">
        <property type="entry name" value="RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42873:SF1">
        <property type="entry name" value="S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="612" mass="68770" checksum="CDC6F8FCFFD1A0D1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8B9</accession>
    <name>A0AAD8Y8B9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Microtubule-associated protein RP/EB family member</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_007840</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MAPRE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8B9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000028">
        <property type="entry name" value="RP/EB family microtubule-associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004953">
        <property type="entry name" value="EB1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036133">
        <property type="entry name" value="EB1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027328">
        <property type="entry name" value="MAPRE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10623">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03271">
        <property type="entry name" value="EB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140612">
        <property type="entry name" value="EB1 dimerisation domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51230">
        <property type="entry name" value="EB1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5 9" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="11">
        <location>
            <begin position="26"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="EB1 C-terminal" evidence="12">
        <location>
            <begin position="302"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="152"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="547"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="153"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="168"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="205"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="255"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="275"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="549"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1741362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="569" mass="61348" checksum="180292C0D7183DE2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8G5</accession>
    <name>A0AAD8Y8G5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8G5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="120" mass="13697" checksum="BF6536D95D2CF047" modified="2024-05-29" version="1">MWTMMSGQSSFDNNNNYHDTNNNNNGPRRVYVHHINEDHINPMGYPPQQQYAPQPPPQPMFIPMPMPIPQPQPMPMPMFMGGMGGGMGYGFHQQPQQPVIIINAVEIKNQTMVVETHLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8G6</accession>
    <name>A0AAD8Y8G6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008071</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8G6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47026:SF2">
        <property type="entry name" value="FLAGELLAR ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47026">
        <property type="entry name" value="PIGMENTOSA GTPASE REGULATOR-LIKE PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="326"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="395" mass="45818" checksum="3E0C603BF14AFA17" modified="2024-05-29" version="1">MMRYTRNELRALHSIFSYHADKVDIHYDENDSASPLFIYPSQIFTVINELGRNEKELSRMNKALTEFQEQQQLQRRDPSSSTAACGSSDSSTITIASLQSNISEPNAVQIVAEVPVGCITFESFASIIDQGWKTQTNDDDECHMHFLGIVNQYQNRCDSEGKYLLAKDFMDQLSSLQKEEENRVVDKVQNMRMVDRAKIVEAHEKQLDEFAQNWDEYLTGFEQKSQEYMAEMQQTHEQQLDSLRKNLTHEIASKPKKWSKDLMDCRKSLENVAKQASAGRPSVSYTQLYREAQQIKQVSDALHEKEEADMNSKFNSVLSAKVRNLEKKQQAEMAALTKKIETKRREVTKKRKEDTLRLQQRNRNIVKMLDAKNKLECSKVASDIQLRMKRVLKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9A3</accession>
    <name>A0AAD8Y9A3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carbohydrate kinase PfkB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007863</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9A3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46566">
        <property type="entry name" value="1-PHOSPHOFRUCTOKINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46566:SF2">
        <property type="entry name" value="ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE ISOZYME 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041908884" description="Carbohydrate kinase PfkB domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="2">
        <location>
            <begin position="45"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="426" mass="45391" checksum="A4ACF1B3A525BDF1" modified="2024-05-29" version="1">MNYLWHLLLLLSTMSATTTHALSTSIVVVGLNAALQKRFILPPNTNLEPGNVHRAHNSETGVGGKGQDVGVAMSCLMSKEKQPRDDKVLLAQFLGMGPEGDAVSGALRLRRGLSDKLTIRNAAPLRTCTTIVGKDCATELVETSGEVTEEELEQLGQKVESLVNDGGKASGVCIMGSMPPGCGDDTYAQLSEKMVGKDTLVLIDSVIGLDALLKTLKSCFESDDREGGAVLKLNAAELCKLAGANKSEAEKVTIEELTAATSCFLTKYECASSALDYLCVTDGKFPGYLVEVPKESTTENKINFIQLPAIDISKQVKGGMLYPIGAGDTVAAGTLAAWQYLHHEPKAGEENFFGVVVPKQVGNILSSVKSKWLSDASSDEKSIKMATSFAFGLSCGSASCLQQENSVFDVDDAVRYFSEMDSPVIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9B3</accession>
    <name>A0AAD8Y9B3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008388</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9B3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1741136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="95" mass="10821" checksum="C7534EB5D0A9C431" modified="2024-05-29" version="1">MKFFAKIAAPLFPLHFHHVALLLIIHGGNGKSMDNLRPLQDLAYTVVFLFLGLQSWWDSQAYNNSTTATGEGISLDDVPLERSWLLHTLYYQHAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9F8</accession>
    <name>A0AAD8Y9F8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_007236</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9F8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="3">
        <location>
            <begin position="120"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="3">
        <location>
            <begin position="376"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="467"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1741663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="487" mass="50479" checksum="E8297EA92CD4595F" modified="2024-05-29" version="1">MAAATEWQVSSEAKTQNEFGDQLLRQLRGGSGGGGGGGGYSGGGGSWGGGSKGNGYYYGSSSYNSSSGDGENPMAVVIVVAVLALFGILYCVLSQNKKGNDPGFQAAVNEERDRERSSFTATAHKSTPQTRCGIGLKRLNGSVTITSIDPNGLFANSGLEAGMTIKTINTVPVATSSAAEATEIIKLAVGQVTIVATGGRSTELDVRGGHPPFETYSGTFDMSYVDRGKQFRGHVILELKNNQRGGYTVTGTTSDADGSAVIIEGLVTHGGDAWWVDEVHSGNDIGLKVLTTGKFDWSTNNFQGAWRSNTGESGRYSSFQATNVSKTFAPVSPAATVAPSSTAPVMTAVVATPVDPSYFQTPIVTAVAESSSPVIVATANKVIKDMSVGIGIKAPDGTPVISSIHPDGLFATSSLRVGMDVQSINNQSMSGKTAGEATQLIKDAVGEIRIVAGWNLSVSTPFTATPMASAPPAETTEEPEVYVPSYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAH2</accession>
    <name>A0AAD8YAH2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_006753</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAH2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF229">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041969750" evidence="7">
        <location>
            <begin position="23"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="8">
        <location>
            <begin position="334"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="48"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="162"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="50"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="198"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1742188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="809" mass="88507" checksum="AD63B5E41A335572" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAW9</accession>
    <name>A0AAD8YAW9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006799</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAW9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF137">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042180380" description="SET domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="414" mass="47298" checksum="9886FBEFE656569F" modified="2024-05-29" version="1">MMQLFITVTFLITAVLGSGSLARDISSLSKWLKNSGVQIHEKIKWKDNGLNDYGLVLTSSVPVGTVLLKVPRTLVLDSQVIKESFKALEADKFHVHEENYWIVWRLYQLKCSSGGNASFAPWINAMPQAFETFTKDEINCLPFYARYAAEYQEAKFASFCNAAAVMKDDDCVFDPANSDHVALLKWAFNAVNSRFWKTNPSENAKIIKQTSELVPLGDMFNHRDPSNVQMIPEDSDYVTFAYKGDDDNDDEDNSTNEKDIFISYGQPSNPHRFLVIFKFAPRAEYMPKLWSHLSYSPTNPYASDFDGMVFDSRTGNVSQTVWDAILWELSEPPSQELYLSFRDKNLMSHKGLLEEVLLNHINQQLEELATCREKISMLDSGSAPNLDIIRQHNDFLTEVFTKVKNNPDNWTMMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAX9</accession>
    <name>A0AAD8YAX9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_006948</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAX9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1742383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="348" mass="39328" checksum="38D5E849F0274EDB" modified="2024-05-29" version="1">MASALSRPACFDSDTLDFSDIGRDLASELTDSDISSIFVSIDAANTLKVLKLIGCENITGVGLEPIRGSTVLRHIDLRISSEHMLLEEAVIQILDSIICREGRALRLIELPDTWRTEKSQMLCEFLERFNNAQNRRTCVCTSCSEGFQGSPWVKHDEAAGGLVWGLQNYTCYDCLKYFCDDCEPPLCQECEKKICEDCCPTYSCGYCDKIACSECDEFDKCDECGSRYCPTCEVSNCAECAHENNVQWCEVCQDEHCNDCRHKAYKEGELPRTGCRGLLLPRITRENEADTRKKQSLRERLDEIESGLTVNLSEADIEFVMNRADCSRKDAIWALRNFIAHTATLLMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCI3</accession>
    <name>A0AAD8YCI3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">OTU domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006656</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1743059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCI3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22771">
        <property type="entry name" value="OTU_plant_OTU7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050704">
        <property type="entry name" value="Peptidase_C85-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419">
        <property type="entry name" value="OTU DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419:SF7">
        <property type="entry name" value="OTU DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02338">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OTU" evidence="2">
        <location>
            <begin position="67"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="225" mass="25240" checksum="92B72F12BA60207D" modified="2024-05-29" version="1" fragment="single">SSNNNNKAKGGGSNNKSSVSGSEKKAKRGGGGNAKRGGGGKSKSNHSSSTSDDDDTQFRNQLLNQGHLIREMNSDGNCLFRSLSDQLYNDDGEEHGTVRSEICDYLERNKDEFQCFLLMNEDDEDIMNIDDYVEHMREHTTWGSDIEIVAASRKYKRGIKVFSTHYGSGVLRFVNHEDNNEQLLDDSFDLLLSYHGNDHYNSVRLIEAAVQRGKISFTNSKECKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCY3</accession>
    <name>A0AAD8YCY3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DnaJ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_005788</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCY3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042407">
        <property type="term" value="P:cristae formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024586">
        <property type="entry name" value="DnaJ-like_C11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052243">
        <property type="entry name" value="Mito_inner_membrane_organizer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44157">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44157:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11875">
        <property type="entry name" value="DnaJ-like_C11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="8"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="168"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="318"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="319"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="345"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1743167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="689" mass="76650" checksum="7A131CF6C3FC5BA7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD78</accession>
    <name>A0AAD8YD78_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glutaminase</fullName>
            <ecNumber evidence="2">3.5.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_005255</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-glutamine + H2O = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaminase PdxT/SNO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.2" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD78"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903600">
        <property type="term" value="C:glutaminase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042823">
        <property type="term" value="P:pyridoxal phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008614">
        <property type="term" value="P:pyridoxine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002161">
        <property type="entry name" value="PdxT/SNO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021196">
        <property type="entry name" value="PdxT/SNO_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03800">
        <property type="entry name" value="PLP_synth_Pdx2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31559">
        <property type="entry name" value="PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31559:SF0">
        <property type="entry name" value="PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01174">
        <property type="entry name" value="SNO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005639">
        <property type="entry name" value="Glut_amidoT_SNO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01236">
        <property type="entry name" value="PDXT_SNO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51130">
        <property type="entry name" value="PDXT_SNO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="55"/>
            <end position="57"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="168"/>
            <end position="169"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR005639-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1743658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="227" mass="24084" checksum="07A82D4A27C66826" modified="2024-05-29" version="1">MSTNNNTITIGVLALQGAFEEHQQCLEAISPNIRTVQIRTPDQLESIDGIVFPGGESTSMGLIGDVTTGLWDGLRNFVHNSGKPTWGTCAGMILLAERCIGTSAVITKGQSLIGGVDILVCRNYFGSQISSFEMSTPAPPAPFATVDATDDDDGKKDNDDSSFPGVFIRAPAILTAPPDVQVLGTVVAAPCRAAAVVLRELERKLEAGENVIQLGVVDALEERLMER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDU2</accession>
    <name>A0AAD8YDU2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein-(Glutamine-N5) methyltransferase, release factor-specific</fullName>
            <ecNumber evidence="2">2.1.1.297</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.297" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDU2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102559">
        <property type="term" value="F:peptide chain release factor N(5)-glutamine methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006304">
        <property type="term" value="P:DNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011639">
        <property type="entry name" value="MethylTrfase_TaqI-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050320">
        <property type="entry name" value="N5-glutamine_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18895">
        <property type="entry name" value="HEMK METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18895:SF74">
        <property type="entry name" value="MTRF1L RELEASE FACTOR GLUTAMINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07669">
        <property type="entry name" value="Eco57I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Type II methyltransferase M.TaqI-like" evidence="1">
        <location>
            <begin position="130"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="256" mass="28558" checksum="F2807782791B8700" modified="2024-05-29" version="1">MSTARKLSSNVGNDTSDAAAAVQAAPDITIQTALNDAVKALERKLVPEPEETGKMVIVSCGKYYGAIYFKLYAGKSANWDFHDLVRLKIKEPMLCPRPETEELVELFWKKYRDQVQVLALDVLPEAVELSNDNAKRFLANHVGGRSIQDGFDVVVSNPPYIPTKDMTTLSEDVSRYESDKALCGGDDGLDIIRHIVKRLPEWTTGNCWLEVDDSHPSLIADWLSPGSLESARFGVECVSTYKDFCGRDRFVKLRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEF8</accession>
    <name>A0AAD8YEF8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005547</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEF8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="419"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="536" mass="60410" checksum="CE02EBF17D940C71" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YET7</accession>
    <name>A0AAD8YET7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Origin recognition complex, subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_004485</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YET7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15489">
        <property type="entry name" value="PHD_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007220">
        <property type="entry name" value="ORC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056772">
        <property type="entry name" value="RecA-like_ORC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14052">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14052:SF0">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04084">
        <property type="entry name" value="RecA-like_ORC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13832">
        <property type="entry name" value="zf-HC5HC2H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger PHD-type" evidence="5">
        <location>
            <begin position="299"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger PHD-type" evidence="5">
        <location>
            <begin position="465"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="525"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="528"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1745194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="814" mass="92354" checksum="30DD25CDB3DB2ECF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFF6</accession>
    <name>A0AAD8YFF6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFF6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042012865" evidence="2">
        <location>
            <begin position="17"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="265"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="312" mass="33002" checksum="46F9825FECD006E9" modified="2024-05-29" version="1">MMKLVSLLGLASAAAAAASSSAANPISSPMLKEASHRILEDGEEGGEEDEGGDDNNNNANLAGYSLQYSTCLRTKIASDDDAVEGNSYYVNGAYRAQYNLYATFRLCTDEGNGKCTCDASVEYATEMDNFLESSLTYLGGAGGGDETDYLECTYGGAENGVDYYLGPQCSDSGGLIIGTFYDEDCTVKAGYSAPSFSYNTFSSIESTCQDCSNGGCNDLYGDAHQCVNGKDIAGDDDEGVCSAAKRATAEVDYSRVKKRNYGAVLFAKVFIGMLVIGLVGGAMFLAYTYYLRHKGDRTEHLVESVPAGAALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFU5</accession>
    <name>A0AAD8YFU5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Staphylococcal nuclease domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_003958</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFU5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031332">
        <property type="term" value="C:RNAi effector complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20379">
        <property type="entry name" value="Tudor_dTUD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.90:FF:000010">
        <property type="entry name" value="Ribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016685">
        <property type="entry name" value="Silence_cplx_Nase-comp_TudorSN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016071">
        <property type="entry name" value="Staphylococal_nuclease_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12302">
        <property type="entry name" value="EBNA2 BINDING PROTEIN P100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12302:SF2">
        <property type="entry name" value="STAPHYLOCOCCAL NUCLEASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00565">
        <property type="entry name" value="SNase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00567">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017179">
        <property type="entry name" value="RISC-Tudor-SN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00318">
        <property type="entry name" value="SNc"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00333">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50199">
        <property type="entry name" value="Staphylococcal nuclease"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50830">
        <property type="entry name" value="TNASE_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50304">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TNase-like" evidence="5">
        <location>
            <begin position="230"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="TNase-like" evidence="5">
        <location>
            <begin position="387"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="TNase-like" evidence="5">
        <location>
            <begin position="566"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="domain" description="Tudor" evidence="4">
        <location>
            <begin position="777"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="969"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1744667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="969" mass="105568" checksum="AD85244E53BAF890" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YG27</accession>
    <name>A0AAD8YG27_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Right handed beta helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003381</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YG27"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042002300" description="Right handed beta helix domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="603"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="603"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="629" mass="68113" checksum="FF8D7ED7D367EB9F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGB0</accession>
    <name>A0AAD8YGB0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_003307</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGB0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1745383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="188" mass="21058" checksum="25301D2BB3F83D27" modified="2024-05-29" version="1">MTNFLIPGVEGAFRPLFEVLDKHGQDCTAIAISAARLGNDIQQRISFVEDTSSAWIKAGYNVLSEDSSAGSTNNDSNSKIHAIFSLTYFENWDEDVDLLGIYKDREAAMNRARVYAKDFIEIDEEQIDNSYEYISRVTNGLLFVEDGGSVSIETATLDEEHGGVDGKEIELSIKDINSVWQDPEVKWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGI7</accession>
    <name>A0AAD8YGI7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RING finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_003777</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGI7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052788">
        <property type="entry name" value="RING-type_E3_ligase_ATL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45798:SF97">
        <property type="entry name" value="ALCOHOL-SENSITIVE RING FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45798">
        <property type="entry name" value="RING-H2 FINGER PROTEIN ATL61-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="495"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="284"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="393"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="428"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="552"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="300"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="317"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="431"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="444"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="459"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="469"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="552"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1745853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="611" mass="67606" checksum="27116EA61F9058EB" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGK4</accession>
    <name>A0AAD8YGK4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Adenosine deaminase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_002806</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(6)-methyl-AMP + H2O + H(+) = IMP + methylamine</text>
            <dbReference type="Rhea" id="RHEA:16001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:59338"/>
            <dbReference type="ChEBI" id="CHEBI:144842"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:16002"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; purine nucleoside salvage.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGK4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004000">
        <property type="term" value="F:adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006154">
        <property type="term" value="P:adenosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046103">
        <property type="term" value="P:inosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409">
        <property type="entry name" value="ADENOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409:SF42">
        <property type="entry name" value="ADENOSINE DEAMINASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="5" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Adenosine deaminase" evidence="10">
        <location>
            <begin position="151"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1746199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="269" mass="29977" checksum="21912994817E9C51" modified="2024-05-29" version="1">MSWGVCSCADVRVSIPHPNNGINDINNKESTSQYAQRAMEEMMYFQSCLLPTQKLFITFPRQTFNVNRNFEHFSALIDLLSDSTLADEDSKHQLAFDFAGQPLPMAQTLPLLDKLRNAFPSSFICYHHGEVCPGIAFSDRVKHTFDLIPYVDRIGHGLCLGLAVLGINPDLDDIKDVNAAVNEEAVLQENKDLAFQCLEQLAEKKIGIEISPTCNITLGGARNEQILTDYVREFLKMGVDVFVGTDDPGFLNTTMEKEIAILQKAGLCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGT1</accession>
    <name>A0AAD8YGT1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_003771</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGT1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="59"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1745847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="270" mass="30236" checksum="80DAA7BD1A6B61F6" modified="2024-05-29" version="1">MVDDIILKTCTACKSVRYCSIKCQKEHRSQHKRACKKRAAELHDEILFKQPESSHEGDCPICFLPISLDNKKSTIKSCCSKTICEGCYHSNEERMFEESLEPTCPFCRHPAPESEEEEGQNIMKRVKANDPACCNGGYDDAFRYENKAAALGDAGAHFLLARFYHEGKCVEKDGKKELYHLEQAAIGGHPKARYNVGCEDKKNGRMDRAMKHWIIAATLGCDDSIDALKVCFRAGIGNKDDFAATLRAHQAAVEATKSPQREAAEEARKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHK4</accession>
    <name>A0AAD8YHK4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heat shock factor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_003593</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHK4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000479">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF206">
        <property type="entry name" value="HSF-TYPE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="6">
        <location>
            <begin position="29"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1745669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="329" mass="36563" checksum="57A84248C2A291F5" modified="2024-05-29" version="1">MMAIRSPASEEGMHSSKKAASSSTSPRRSKSEFPIKLYAMLELADNIPVFARAVTWLPHGRAFKVLDEDTFMEEVVPAFFNQTKIRSFNRQLHLWGFRRIGRGNEKVWFNDNFLRGVPASMEHLVRTKIKGNTVGSIDDGKIPNFDDMPPLPICDKHPSDVLNEIENAILKIHSSSIAHRDLTMSTLSRASFNDVTDHPTVSLGSESPCEFSVDVDTDESFMSPPSLLPAASNGSQGQGVPFMRFHLPLQASTSESMTYTNQTSVEGSSHQAQSHVMRQADFNDVCFSPLKHSNDDFEPLPFWVDNDSCVSDDFANFIGGAIQNVDFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHQ4</accession>
    <name>A0AAD8YHQ4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">S51 family peptidase</fullName>
            <ecNumber evidence="6">3.4.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_004601</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S51 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHQ4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005320">
        <property type="entry name" value="Peptidase_S51"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20842:SF0">
        <property type="entry name" value="ALPHA-ASPARTYL DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20842">
        <property type="entry name" value="PROTEASE S51 ALPHA-ASPARTYL DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03575">
        <property type="entry name" value="Peptidase_S51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042087410" evidence="5">
        <location>
            <begin position="26"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1745310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="327" mass="35991" checksum="DBF42C6271E86924" modified="2024-05-29" version="1">MRQTTAAIRTLLFYAALLSHSPAAAFSFNSVRNQQRNSIHHASVESVETSSDLVESSSTPSSNSRWATNALLFSSWTDGIVTNHAAKSFLRYSIVNKLLQDHVVDKEDGLETSVKFSPCNGPDVEKLNNLEAADILSDRGKQFAFDAFDAAVRNEVDSWSKETLQYISTETGEVTDGKEALSTWNPTVIYVEGGNTFWLQHCIDKGQYSQLIIDACTGESGAVYCGKSAGAIVAGDDVSTATWKGWDDPSVVPNRETYDDWIGTRGFQFSESLSFFPHMSDDWIELVNDKVKGKEANSTCCLREEEVCCITGERKQRFVVSGAAPEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YI05</accession>
    <name>A0AAD8YI05_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Chlorophyll a-b binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_003270</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated. Energy is transferred from the carotenoid and chlorophyll C (or B) to chlorophyll A and the photosynthetic reaction centers where it is used to synthesize ATP and reducing power.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fucoxanthin chlorophyll protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YI05"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030076">
        <property type="term" value="C:light-harvesting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="8" id="KW-0157">Chromophore</keyword>
    <keyword evidence="7" id="KW-0437">Light-harvesting polypeptide</keyword>
    <keyword evidence="5" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041968692" evidence="9">
        <location>
            <begin position="17"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>4</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1746663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="258" mass="28107" checksum="07A4F19E6D8AB158" modified="2024-05-29" version="1">MMKLALAAALAGSAAAFAPAQQGSAMKTSMDAMPDRMWDKMVDKTERSASMPFLPRPVNLDGSYVGDVGFDPFYLSSIPKNFAGFIQPPSWEDVEGISTLYWMREAELKHGRVAMLAWAGWLAADGAFGPVPLRFPGSLYQDVPDSYHAHDIMVSQGSLGFMLFVIGFIEFCTSAVLVEVSKGESDREAGDFKLDPLQFLKGKSKEDVDMMKLKELQNGRAAMMAFGGVATQAALGGTEFPYLVPYAENGLPSIDFTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIN9</accession>
    <name>A0AAD8YIN9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Autophagy-related protein 22 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_002337</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIN9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050495">
        <property type="entry name" value="ATG22/LtaA_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23519">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23519:SF1">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="320"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="356"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1746993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="423" mass="45788" checksum="6DEDFE770DBC6491" modified="2024-05-29" version="1">MVLQYNALESFTENDTTTEVRAPTADSSNQKQPSNLIPSIFRFDNDNSPIEATGLALNSIARGLVGMSSLFLGPALLILAQDAANEASGCNTTNNNDDGQNDCSDDDDEGRVYGMRPSSLLTNIGVFSGVFSAILLPLFGAIVDHTPHRKAIGQWAAILLSIIKGLKSSHLCAAYAYTAELSIDPKEQTIYNARFQTINYFSMLAFLIVVTLTSSLLHVGDMVKHEYRKHWHSSYAPSYLALLGSGSSPALRQVPDNSTLLTAGFRKLSHTSSEIIQHWAPLRYFLLSVMLSESATGALSTISTTYMIHVLNMTSSQIGYVFLCVFVAGIPGSKLVWTGILWVPPFLFTFLNEIGASMRIGLGSLNLFFAGGFVFLKMIGDYQDAVDFALSRGVGGDGDDTWSSKDSCDGSNGAKRLSLPELT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YK18</accession>
    <name>A0AAD8YK18_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alcohol dehydrogenase</fullName>
            <ecNumber evidence="6">1.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_002051</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.1" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YK18"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050129">
        <property type="entry name" value="Zn_alcohol_dh"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43401">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43401:SF2">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="5">
        <location>
            <begin position="8"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1746707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="326" mass="34735" checksum="B3DE27182A65DA4B" modified="2024-05-29" version="1">MEAVRYHGPNEALTFETVPIPTEADLSPDEVIVRVEASALCHTELHFADGTLNLGVKPITLGHEAVGVITAVGSDISPSRIGQRVINYYYVGCANCRWCNRGDQQLCPNLKAEHGFISDGGLAGYIRTPSRNAVVIPDSLEFVDAAPIGCGVTTAVHAAKLGRVDSTQDECALVYGCNGVGFGLVQSEAKRKMAIELGADFVIDGTDASSVAAAVREKTGGGEGVDVLFECVGTRDTLDSCVGWVGALGRRGRLVLVGYHQGEEHEFRCHPIPMIVYEQTVVGSVGATLEDLKEAVKYVGEGKIRTVVDSTISLNEFQNGLDRIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YK42</accession>
    <name>A0AAD8YK42_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">WRKY19-like zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YK42"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056866">
        <property type="entry name" value="Znf_WRKY19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24906">
        <property type="entry name" value="Zf_WRKY19"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="1">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="119" mass="12718" checksum="32C0E4DE5AA5500D" modified="2024-05-29" version="1" fragment="single">PNQARARGVCIRHGAKVKRCSSEGCTNQARSGGMCIRHRAKDKAKKCSSEGCTNPAQNGGVCKRHEAKVKICINEGCTNQARDGGVDCVECAVQSSDCATAMDARTLSSKEEWSSEENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKJ7</accession>
    <name>A0AAD8YKJ7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rossmann-fold NAD(P)-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002139</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKJ7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020">
        <property type="entry name" value="FLAVIN REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020:SF11">
        <property type="entry name" value="OS06G0360300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042232958" evidence="1">
        <location>
            <begin position="20"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="NAD(P)-binding" evidence="2">
        <location>
            <begin position="100"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="362" mass="37660" checksum="AF615DA89A2E7919" modified="2024-05-29" version="1">MKAAITLVALSFSATALHAFSPTPAVLQQQHSIRSASSSVLQLRATAESSSSDVTKDTSSTCRRSFLVGASGTVAAVALSLQQPALAADDTKKQPICVIGCNGRTGTEVVKYLIAKNEPIKATSRTGEYNDAASVPAGAMLEQLVCDVTDPKSVNLACAGTSAVIFAASASKSGGTPSAVDNAGLVNVAKACMDANVPHLVVVSSGAVTKPSSPVYQFLNLFGNIMEEKVKGEDAVRKLYAEHNANLGEGGQKLTYTIIRPGGLTLDPPRGVAAIELNQGDTKSGRLARADVAQLCVESLNYPHLTGETTFECYDADTGAPLATVGLSNIAKKKTDGEVFVSGFERRGNTYEELFTGLQKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YL27</accession>
    <name>A0AAD8YL27_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histidine phosphatase family protein</fullName>
            <ecNumber evidence="2">3.1.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000523</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YL27"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF10">
        <property type="entry name" value="2-CARBOXY-D-ARABINITOL-1-PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="9"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="241" mass="27553" checksum="1D94383675FCDB8E" modified="2024-05-29" version="1">MCFTVYVMRHGQTDANANEIEQGSADFSRLTDLGKEQASNAYQALVDTRVTSIYTSPLSRARQTLEQLRQADASSTQTVLPPSDLILNDLREIDQYDWQGQSYSELKRQFPESWRAWEKGIPDEMKVLETATNVVHYPLLEMWERADRVWSEMLDLEKKRQDDDNEKDRSVLIVAHGNLGQALLGSAMGWDANSFNEKGVFGNCGCAEIEFLDLDTSPRKIANRWRWQWPVPSAWSPTTTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YM41</accession>
    <name>A0AAD8YM41_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YM41"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1749121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="253" mass="28833" checksum="5ABCB28BEA52A045" modified="2024-05-29" version="1">MATEYPHAKHNMTALAPSTNVQKQRKANPKIDERQKVYWDLQGRYQEEYDRRVDALPQYGEGATKASEIFRAATKLYYDFWNNGMVNNTSGAVNFLLYAGVFTSEQDQDFAVIHPYTIGLKIYLNEIELRCTMERMLDRTIAFLLANHELDALPNDMDYLEFSQQSEMNNLDRCTMRNIHFLKMKENAAAASVALVAATSADEAEASLMRTHSSKAQDCTMKKKKKGKKKRVPSAKNLANIMTGINRITISKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YM99</accession>
    <name>A0AAD8YM99_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RanBP2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_001168</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YM99"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RanBP2-type" evidence="5">
        <location>
            <begin position="4"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="32"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="123"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="223"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="68"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="86"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="128"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="190"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="223"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="241"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="373"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="397"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="421"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1749229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="448" mass="49755" checksum="4F7D9A5093836A0D" modified="2024-05-29" version="1">MPAWECYACTWLNDECNIDCLMCQTKRARNLSPNARKTEESTVCRQAADDSNDAVPEKSLRQQNNDVDNNRKEPTKEKVKPLVRNQEVSTQIQHSQPSNQQEKVSEVNESNSKWDAFASLENNYESSDSGEDESDSDSDGSDVSEHYYGDSKDEKEQCDEGKDGADQSQWNAFESLEATLGDDSSSSSGEESDCILIEDNDEKKIAPAATSIKSNFKTECVDLVDTDDEEDVRQEKDTKPKRINSRKRKRASDQSAITLMDGDSDSSYLSEVESSRPLQPSPATRQGRRSLPPWQRAARSKSKSPSILQNERVLPRESFSLLSNRNDVSGSGLNETRTSAPAARQPRQRKSSTTTKSGSRRRKRSNSDGAAPAKKKRRTRKYRRSSKRGGRGGRGGAAAASGSNRSNNAWSARERGIRQPISGNNGSYMNITKQEPMLRNIGGASIQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMF3</accession>
    <name>A0AAD8YMF3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_001774</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMF3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF226">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13578">
        <property type="entry name" value="Methyltransf_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="6">
        <location>
            <begin position="272"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1747811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="711" mass="78981" checksum="E15890B74D4D9F46" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMG5</accession>
    <name>A0AAD8YMG5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001017</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMG5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042103394" evidence="2">
        <location>
            <begin position="41"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="261"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1023"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1749078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1023" mass="110810" checksum="8DEF6544187529B7" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMR3</accession>
    <name>A0AAD8YMR3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001167</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMR3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17744">
        <property type="entry name" value="BRCT_MDC1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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        </location>
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        <location>
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            <end position="276"/>
        </location>
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        <location>
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            <end position="441"/>
        </location>
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            <end position="841"/>
        </location>
    </feature>
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            <begin position="921"/>
            <end position="1003"/>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="225"/>
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            <end position="238"/>
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            <begin position="239"/>
            <end position="249"/>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <end position="363"/>
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        <location>
            <begin position="703"/>
            <end position="712"/>
        </location>
    </feature>
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        <location>
            <begin position="744"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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            <end position="802"/>
        </location>
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        <location>
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            <end position="819"/>
        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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            <end position="841"/>
        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="921"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1749228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1066" mass="116825" checksum="0823503071970F87" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YNI6</accession>
    <name>A0AAD8YNI6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WRKY transcription factor 19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YNI6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="436" mass="46482" checksum="6D444B824D723232" modified="2024-05-29" version="1">MVDNRRDRAPNSEDAWQSFVRKKKEQEARKLSTPKNDDANQNNDLFATHVSLTASSTASKADTSNPEMSSDVDNSAVMATGAVKGGNPDMILNPPDSSKITMEGRRLQPKIHEFTPSQINDNAAVEGGGDHDPHVSLPHLPNENNDAIVAGDGASPTIPSIPVNNGNGPATCQSTANNHMRNDYAVFDAERKEKIMMRKKKKRKLCTAEGCENQARNGGVCVKHGAKRKLCTAEGCDNQVVNGGVCVKHGAKRSLSTSNKRKHNDNAASDEERQVARKKRKLCTAEGCENQARNGVVCVKHGAKETRNLCTAEGCESQARNGGVCVKHGAKVTLCTAEGCESQARNGGVCVKHGAKKKRKLCTAEGCENQARNGGVCVKHGAKRKLCTAEGCENQAARGGVCVKHGAKVKLKVKLCTAEGCENQAKNGGACKRHGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4Q8</accession>
    <name>A0AAD9D4Q8_9STRA</name>
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        <submittedName>
            <fullName evidence="8">ATP-dependent RNA helicase</fullName>
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        </submittedName>
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    <gene>
        <name evidence="8" type="ORF">QTG54_015234</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
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        <lineage>
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            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
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            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
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    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
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                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="8"/>
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        <property type="protein sequence ID" value="KAK1733976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4Q8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF119">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="322"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="588"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="32"/>
            <end position="60"/>
        </location>
    </feature>
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        <location>
            <begin position="79"/>
            <end position="106"/>
        </location>
    </feature>
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        <location>
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        </location>
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        <location>
            <begin position="234"/>
            <end position="261"/>
        </location>
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    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="49"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
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        </location>
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        <location>
            <begin position="142"/>
            <end position="157"/>
        </location>
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    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="240"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1733976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1188" mass="131337" checksum="B918307B503F6339" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D510</accession>
    <name>A0AAD9D510_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000053">
        <property type="protein sequence ID" value="KAK1733140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D510"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="372" mass="41477" checksum="517B3A2C522DB33D" modified="2024-05-29" version="1">MVSFISTTRSTKNAEAKKQLQLQSTFEEEEDDQNYNKMTGHTSFTDNAGTPSNMVFEVDNYGTAAAETDTIFDKIINMWSEDISCDFGMQSAREQALEVEAAAEAEAAAKAELEQLKQEKKRTSNRKKRKKRKQAADQAKEVEVEVTYVGEAKQARDLDVEAADAKVKQRVHARKAAEARQRQALIEAAQAKKASEGPAQQAAAARRQLKRATEAMKMAKMEAKKAKMLAKKEAKQAKRAEKEAKRQAKEERLARQKYAKAQAAAAKKVAMEEERKAAATRRLLQQMEEEESQLREKEEKIRSLRQRLKAASTDGDLAVAGGLKDFETVVSVSEEDDCSTVYTVDDEEEESRAGITQVLSDMLEEASILLGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5I7</accession>
    <name>A0AAD9D5I7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosome quality control complex component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_015535</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000045">
        <property type="protein sequence ID" value="KAK1733680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5I7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990112">
        <property type="term" value="C:RQC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
        <property type="term" value="P:rescue of stalled ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059101">
        <property type="entry name" value="NFACT-R_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051608">
        <property type="entry name" value="RQC_Subunit_NEMF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15239">
        <property type="entry name" value="NUCLEAR EXPORT MEDIATOR FACTOR NEMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15239:SF6">
        <property type="entry name" value="RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18297">
        <property type="entry name" value="NFACT-R_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05833">
        <property type="entry name" value="NFACT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041994500" evidence="3">
        <location>
            <begin position="27"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="NFACT protein RNA binding" evidence="4">
        <location>
            <begin position="295"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="80"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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        </location>
    </feature>
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        <location>
            <begin position="415"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
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            <begin position="123"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="81"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="265"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="433"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="445"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF18297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1733680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="475" mass="52847" checksum="5D5D9CA37DE0BF31" modified="2024-05-29" version="1">MANPIFLRSTLLRPAILVAIASRAQAFVNIAGTCGQHLYQRNGVSNSLGRQAQHRLASSSVGHDEDTILQTVAATATFESSIEEDDDDDFEDDDDDDNSESSIQPSQSQLLYNALSKSITSALTSLTKKKASLENELAKAQKLETTMNRANLIVSNLYRLPPGTTELEVEDWENDGNIVKLVLNTKDYTNFQEESDALFAAARKMKRGSAVVEELLAKTLEGEEALNDAQMDLQSMESSVLDEGTMILIQERLERTAKKTGWKPPKIEQSEEQSKPRRNTTKKSQGNKARTPNPRELTSPSGHKVLVGRNRRDNEAICFALSKPTDIWMHARGCPGAHVLLCSRRGSPKVTDDDLQFAADLAAFYSDARTERRAEITTAEPKHITKPRGAPPGAVTLRQEGKTLLGKPDDVAEELKEARELSGANWSELGYRKGGKRANNKKKTAAVEKETAKKRREEARENNKRRKRKEETDWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6R1</accession>
    <name>A0AAD9D6R1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012841</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6R1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042138481" evidence="2">
        <location>
            <begin position="18"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="151"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="193" mass="19923" checksum="F4B1E2F43E10C393" modified="2024-05-29" version="1">MKIQIVFLSLFLAAAHARHEPKGKGLRGGDDRDLELVGSTVVPNGSSATINCGSGSQCCVTGTFKTINNVGSKTTTCQGSTLSNGSLGNCQSNSCSVSCDGVCNVVVKAGSGSAGDGGDGGYDNDGDYGYDNDDENDGDNEYDGGNGYSGYPGYPGYPGHSGYSGYPGNGWGQDEGEEDDYYDSELDTFMEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8E4</accession>
    <name>A0AAD9D8E4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012550</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8E4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="129"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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            <begin position="252"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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            <begin position="358"/>
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        </location>
    </feature>
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        <location>
            <begin position="582"/>
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        </location>
    </feature>
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        <location>
            <begin position="644"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="907"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="793"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="19"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="141"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="164"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="258"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="358"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="596"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="651"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="913"/>
            <end position="929"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1121" mass="124258" checksum="AC261EBD9BC87214" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8R6</accession>
    <name>A0AAD9D8R6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_012303</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8R6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17325">
        <property type="entry name" value="MFS_MdtG_SLC18_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050189">
        <property type="entry name" value="MFS_Efflux_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43124:SF3">
        <property type="entry name" value="CHLORAMPHENICOL EFFLUX PUMP RV0191"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43124">
        <property type="entry name" value="PURINE EFFLUX PUMP PBUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="359"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="395"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="420"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="450"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="565"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="600"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="639"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="677"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="711"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="740"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="325"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="93"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="201"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1736858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="771" mass="83054" checksum="82252527EF7DB575" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8S2</accession>
    <name>A0AAD9D8S2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="17">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="17">3.6.4.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">QTG54_012439</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="17"/>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11605">
        <property type="entry name" value="RWD_DRWD_ELF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1740.10">
        <property type="entry name" value="Zinc finger, PARP-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059023">
        <property type="entry name" value="RNA_hel_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001510">
        <property type="entry name" value="Znf_PARP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036957">
        <property type="entry name" value="Znf_PARP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF12">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26026">
        <property type="entry name" value="RNA_hel_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00645">
        <property type="entry name" value="zf-PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01336">
        <property type="entry name" value="zf-PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50064">
        <property type="entry name" value="ZF_PARP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 17" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PARP-type" evidence="12">
        <location>
            <begin position="275"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="406"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="13">
        <location>
            <begin position="1089"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="16">
        <location>
            <begin position="1203"/>
            <end position="1362"/>
        </location>
    </feature>
    <feature type="domain" description="RWD" evidence="14">
        <location>
            <begin position="1872"/>
            <end position="1976"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="2078"/>
            <end position="2257"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="16">
        <location>
            <begin position="2353"/>
            <end position="2547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="55"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="587"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1400"/>
            <end position="1438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1567"/>
            <end position="1603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1993"/>
            <end position="2048"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="2283"/>
            <end position="2326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="72"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="116"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="138"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="163"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="193"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="588"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="633"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="675"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="707"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="733"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="747"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="771"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="784"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="812"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1400"/>
            <end position="1413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1567"/>
            <end position="1590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="2001"/>
            <end position="2010"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="2018"/>
            <end position="2031"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="2287"/>
            <end position="2297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="2307"/>
            <end position="2317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1736994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2941" mass="323974" checksum="C5D380FD293CEE9F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9L7</accession>
    <name>A0AAD9D9L7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009889</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9L7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="157"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="243"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="311" mass="35561" checksum="A4FB13DF9AC0A310" modified="2024-05-29" version="1">MKMTNRQWFQKTKLTYNPVKRKRDKDKTKKDSNSGTSAAAATAAHDHASSPSNLHSEIESDARQKERNELRDARRKEREERRKQFDKLQDKRDGKSSTQKKKEQKISQEERDKRDAQLGCCHRFTQFLVKLIHVIDAIIGLACVIYGVFIFRFTQPAMAAVITFLTFGSLMLSTSIVGTIGFCTSICRRWGIALSAWSAACIAFFYMFVIIALLADPDTCFNYLTANQSVLFLNDASIAMIRMWLPAIYIACACLAVVETCRFFVLRKLRNTLLRYDAAQRSISERSKQQQDSNRTILTAPLLEDDQSWVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9S1</accession>
    <name>A0AAD9D9S1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RAD52 family DNA repair protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_009994</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RAD52 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9S1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045002">
        <property type="term" value="P:double-strand break repair via single-strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.80">
        <property type="entry name" value="DNA repair protein Rad52/59/22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041247">
        <property type="entry name" value="Rad52_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007232">
        <property type="entry name" value="Rad52_Rad59_Rad22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042525">
        <property type="entry name" value="Rad52_Rad59_Rad22_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12132">
        <property type="entry name" value="DNA REPAIR AND RECOMBINATION PROTEIN RAD52, RAD59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12132:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD52 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04098">
        <property type="entry name" value="Rad52_Rad22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="225"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="318"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="382"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="256"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1739451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="420" mass="44695" checksum="08C2EDA0F152EC2A" modified="2024-05-29" version="1">MSDGSNQKDFIENADGSLLLDHKGQPISVDKFLSTKPLRKEVSTRQGPGGMKLSYMGGDVITKTLNEAFGYDGWSLEVKDKTQLDPMKDDKGRYIVAFTATVRITHLRTGAFREDCGAGDAIDRSLASASGNALKGAVTDAMKRAARHFGEKLGNSLYHDDFSVNKAPNTLKDACDMLDLERAKGRFGFDKDRKKMIPAQQQQQQQSTAVTSSVAVAATTTTTSQTAVKGGGGLQHSHNNNYTKPPPPLYVGGCVAQTQQQTPRTVQSTVSNQPKTKNSNASKPYVTPHHGMMNSNRTPGNGIAPSRPATAIAATSKVNENANPQTTKLLPPPKTGGLNLPKRPGTSRGVGNNNSLGGDEVMKAFYGSSSDVAATTAAPSMFERGGGMSQALMTSQQSLKRKSDGADGNPNPMKNPYTQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9W6</accession>
    <name>A0AAD9D9W6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Dynein axonemal assembly factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_009345</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9W6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050576">
        <property type="entry name" value="Cilia_flagella_integrity"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45973:SF9">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45973">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14580">
        <property type="entry name" value="LRR_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1739586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="388" mass="43503" checksum="AB84A5A3950DE2A0" modified="2024-05-29" version="1">MNESTTALEGLPVMSREELLKVALENGGYSTPSLNDTLYLHYKGYRRIENLDKYDGLKSLWLHSNGFERIENLSHLKELRCLFLQRNAFSSIENLQGLDSLVQLDISENSIRVVEGLDHLPNLTTLNLSKNVLEDAASIQHLVECKNLSAVDLSHNKLAGKDVVACITGIEKLTSLNMSGNPVCSKVAYFRKKMIVANKSLRYLDRPIFDNERATAEEWARAGPGAEQELKAKLLAKKQDKERNAMQEFRQWQESVRTTTVNNNTEVEDAVVLRDTMEALITAVEVKSLLLKTDTVVNEEKQVVEVELAECKTVEKEKENVEPQDDFVAQKVKSLSLYLNSKGQRKTLEDLLVDSSKVPAVVLPPDALSFDVVSSDDDEETDLMSTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9Z2</accession>
    <name>A0AAD9D9Z2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009346</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9Z2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="155"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="318" mass="36751" checksum="BE78C19171B57080" modified="2024-05-29" version="1">MSNTHNDKKRKRSRSDDQLAPAVGPHVIQWLGKRKKKVPDALSADKNNHMQMEQILRLLALKERERRALVRYVEKRIDEEKNGGPKKVELQDSDGEYDVKNSAAAASHHHKQQELWPTSVTFSNNYDWESSVPADTKEKYYPSNKIRQRANHFSRNVYFKRITDKDHPAYGEFGLYCALAHAKPGQWLLDYVGRVTLGEDQNKKSDYVSDFGEHSELACDANLLGNEARFLNDFRNTGNYPNVEFNFRRDRNGEFRQGVYVKQVKEAKEKGFDGIKQDEELLVSYGKSYWKSRVDGGDLTEFVWRLPNQPMPPGGKPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DA85</accession>
    <name>A0AAD9DA85_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Lipase maturation factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_010659</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the lipase maturation factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DA85"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009613">
        <property type="entry name" value="LMF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057433">
        <property type="entry name" value="LMF1/2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057434">
        <property type="entry name" value="LMF1/2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14463">
        <property type="entry name" value="LIPASE MATURATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14463:SF10">
        <property type="entry name" value="LIPASE MATURATION FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06762">
        <property type="entry name" value="LMF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25179">
        <property type="entry name" value="LMF1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="123"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="278"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="Lipase maturation factor 1/2 N-terminal" evidence="9">
        <location>
            <begin position="313"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="Lipase maturation factor 1/2 C-terminal" evidence="10">
        <location>
            <begin position="558"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="66"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF06762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF25179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1738629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="710" mass="80501" checksum="153205DCB1EDEDEE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBD5</accession>
    <name>A0AAD9DBD5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009513</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBD5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1739754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="81" mass="9110" checksum="2B15AC477BCD3EC1" modified="2024-05-29" version="1">MSKWTPECDGHLLALVTGFTENGQNPAFTAIAEHLNKMPCFTWTVTGKSVNARYKDYLDPSVIRGNMTQFEIEASFPSKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBU2</accession>
    <name>A0AAD9DBU2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_007334</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBU2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1741761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="99" mass="11072" checksum="06154B71728AF599" modified="2024-05-29" version="1">MSTPDRKDHIRVKRRNQTFFIPTAPSDSFAYIKEEICKALGGDDDSIDVKAMRLYVDNKSEGGDADAGKETKKEIPDAALLSDHDVKNDDIIILEMDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBX3</accession>
    <name>A0AAD9DBX3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">PHD finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_009304</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBX3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15567">
        <property type="entry name" value="PHD4_NSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46508">
        <property type="entry name" value="PHD FINGER FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46508:SF1">
        <property type="entry name" value="PHD FINGER FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="187"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="298"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="375"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="659"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1035"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="304"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1043"/>
            <end position="1060"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1740354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1177" mass="130919" checksum="3A01C49D1D43895F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DC67</accession>
    <name>A0AAD9DC67_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidylinositol-4-phosphate 5-kinase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009305</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DC67"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215:SF14">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="120"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="515" mass="57898" checksum="87F17DB00C4F5DB9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCK6</accession>
    <name>A0AAD9DCK6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">AP-2 complex subunit sigma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_007017</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCK6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016635">
        <property type="entry name" value="AP_complex_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11753">
        <property type="entry name" value="ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="7">
        <location>
            <begin position="28"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1742452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="115" mass="13177" checksum="4CE40286BDE4A611" modified="2024-05-29" version="1">MVRPSPQLRAGATANGFSSADYSANNQTEAEKARIEAEVHRLVTSRDKKYTNFIEYNNYKLIYRRYAGLFFTIAVDVQDNELSYLESIHLFVELLDSYFANVCELTLCLTSTRCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDA0</accession>
    <name>A0AAD9DDA0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein tyrosine phosphatase family protein</fullName>
            <ecNumber evidence="6">3.1.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_006017</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDA0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46274">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46274:SF6">
        <property type="entry name" value="TYR_PHOSPHATASE_2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="4">
        <location>
            <begin position="142"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="5">
        <location>
            <begin position="211"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="306"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="355"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="374"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1743396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="385" mass="43216" checksum="CE89B58DA7A1B4D8" modified="2024-05-29" version="1">MNMATPPNSGRFGVNTNHQPRINSDSFSSVTATTGKGKKNNNDGDGSNDDDDDPYPYISGGGQKEHRSSVPLSSLRGSTEHNVSLLSGLGLAKLCFRSVAFATITLYVLNQKHILPKPLGMVVSRALFWPTLPITVSRRIGKWTTVVDNAVVLGGAPFGFLNYPEKLHSQFRVRGVVNMCEEYQGPVKSYRRLGIEHLRLPTVDHFEPSVEDLKKAVAFIQKHESKGGRVYVHCRAGHGRSAAAVYAWLLYKEPLADPIELNEKMCALRNVRKSLHSQPNVNKFRTWLQNGGMVSDSDDEEEFYWPRKKQASESSQQHRTRKDSTRSRTGDGYGLDSESDGDVYPASSLGRVFSDEDSTEDDWDWSGDERSQYDDEYYDYSEDEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDZ8</accession>
    <name>A0AAD9DDZ8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Purple acid phosphatase</fullName>
            <ecNumber evidence="5">3.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_005713</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.-.-.-" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDZ8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00839">
        <property type="entry name" value="MPP_PAPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041792">
        <property type="entry name" value="MPP_PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039331">
        <property type="entry name" value="PAPs-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025733">
        <property type="entry name" value="PAPs_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22953">
        <property type="entry name" value="ACID PHOSPHATASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22953:SF153">
        <property type="entry name" value="PURPLE ACID PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14008">
        <property type="entry name" value="Metallophos_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="3">
        <location>
            <begin position="13"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Purple acid phosphatase C-terminal" evidence="4">
        <location>
            <begin position="192"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1744116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="285" mass="33195" checksum="CC4A6695EF9E59A3" modified="2024-05-29" version="1">MDLMSKRDFFNAIPTQIALGNHDLDTYKHGWIYDINESVEIALAYEHRFQMPQIRPPIRELASLKGFTTSGQPTDFVPYEYGNAYYSFTFGPSKHIVLSSYSSFREGSLQHEWLLSELKSVDRSVTPWLIVMIHCPLYTTFKTHRREIFITEAQAILEPLFVKYTVNFVISGHVHAYMRTYPMAFSRRNPRGPVHIIQGNGGKAVCEPYYNETVEEWVAVRDQSQYGYGTLELFNSTHAMWKLIKTGHDEGGEFELNLNLLDEIWVRNQLYVEEMSVNKDWEDNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DE55</accession>
    <name>A0AAD9DE55_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ubiquitin-like domain-containing CTD phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DE55"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090364">
        <property type="term" value="P:regulation of proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051658">
        <property type="entry name" value="UBLCP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48493">
        <property type="entry name" value="UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48493:SF1">
        <property type="entry name" value="UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="29"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="318" mass="36198" checksum="62D31ECD63CA1D3D" modified="2024-05-29" version="1">MDAATAATTTMVAKYGKQKIELSDLPSTTTTIGQVKDLLREKTGILPIRQKLIGLKTSTKGQELTDATLLSELKQSKRASIYIDGTPEEEIFVDPSEKDDLPAVLDDFELDFNAGSEEWIQHKAKEDNLQKFTESTAVHIINPPRRVSSESDKYKPLLVLDLDHTLLTFREVICKRMGIPQRPWVPLMMLLPINSNDPTWMNIVEMARVKLTELGMLTHPGYKFCFVLDKTSMFQIPLQIIWTKFPHWGAHNTVHLDDLKRNFALNIGNGLKCSAYYRKKKKSGKNDSELLGLDDFETVQFDYWQDYVSGKLGFGKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEA2</accession>
    <name>A0AAD9DEA2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Potassium channel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_005024</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEA2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015271">
        <property type="term" value="F:outward rectifier potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022841">
        <property type="term" value="F:potassium ion leak channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030322">
        <property type="term" value="P:stabilization of membrane potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003280">
        <property type="entry name" value="2pore_dom_K_chnl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11003:SF291">
        <property type="entry name" value="IP11374P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11003">
        <property type="entry name" value="POTASSIUM CHANNEL, SUBFAMILY K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="96"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel" evidence="9">
        <location>
            <begin position="64"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1744491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="126" mass="14113" checksum="46B74D4B8980A8DA" modified="2024-05-29" version="1">MFPTLIRPIKKRKLKCMDGEPTGALLQLCRRRSCRRQGTYVARYDALEKSFADANGFDDEDCFPNMWAGSWFWFTIMTTIGYGNTAPATDGGRIMIFTLGFVSILFFGFVLGKAGSIVVAIVEDSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEC1</accession>
    <name>A0AAD9DEC1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Protein HIRA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_007123</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat HIR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEC1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000417">
        <property type="term" value="C:HIR complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031120">
        <property type="entry name" value="HIR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011494">
        <property type="entry name" value="HIRA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13831">
        <property type="entry name" value="MEMBER OF THE HIR1 FAMILY OF WD-REPEAT PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13831:SF0">
        <property type="entry name" value="PROTEIN HIRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07569">
        <property type="entry name" value="Hira"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3 9" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="73"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="261"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="403"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="Protein HIRA-like C-terminal" evidence="11">
        <location>
            <begin position="976"/>
            <end position="1203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="11"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="115"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="186"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="454"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="517"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="568"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="722"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="835"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="141"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="192"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="232"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="467"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="519"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="579"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="842"/>
            <end position="851"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1742558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1272" mass="135506" checksum="0F61F7FA1D564A65" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFT6</accession>
    <name>A0AAD9DFT6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3'(2'),5'-bisphosphate nucleotidase</fullName>
            <ecNumber evidence="2">3.1.3.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_005147</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.7" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFT6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008441">
        <property type="term" value="F:3'(2'),5'-bisphosphate nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050725">
        <property type="entry name" value="CysQ/Inositol_MonoPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43028">
        <property type="entry name" value="3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43028:SF5">
        <property type="entry name" value="3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042197335" description="3'(2'),5'-bisphosphate nucleotidase" evidence="4">
        <location>
            <begin position="18"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600760-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1744614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="403" mass="43476" checksum="885AA81BC80C45CC" modified="2024-05-29" version="1">MQILSLAVVAVVSMTEAFAPVALSSRRSVDSTLQASDKPLTELCEITKEACDAVQPMLNELYSQIKIGTGVADTAAFKSDATFFTIADGIVQHMFIEYLFAGDKFAEIVGEEDDSVVNILETPFTVDDLVVPDEFEELVTETLAKVQALSSRIDANAYKDLTVFVDPIDGTREFATGKGDKVTILVGYNDPAGHPQAGIIYRPLTTPNYWASGAKSEGFKDGVLDTPDEINSKGLLITDGKVSPFIMSTIENSGMNMVPSLASGNRVLMLVEGKAGAYIRDTGGFAKWDTSGPQAVLEAHGGVMAKLPEFLVDKSMVSYTHLKTPLNLDFCKMSVGLTLSNAKDKAMFIPGLDSIVKDVHLVKEYSCLQGLVALAPTKMEAFYLNAIHSAMNNIKKKSPPTYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFZ6</accession>
    <name>A0AAD9DFZ6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003676</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFZ6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="462" mass="48378" checksum="565488BF3FC7DD4D" modified="2024-05-29" version="1">MNRPILQPATTPAPSPSSPEAEQTYCGCPQCTQAVWDTLACDDALEDGCHTCGSRISWLQSNNGGNIDNACHMVASQFPSGPCGVCNPDTRNVTAEPTKSPSLPPTPKPTPLSTLAPTPNPIKVSTQAPTSTPDDTYCGCPQCTQAVWDTLACDDAVEDGCHTCGSRISWLQSNNGGNIDNACHMVASQFPSGPCGVCNPDTCNVTAEPTKCPSLPPTPKPTPLSTLAPTPNPIKVSTQAPTSTPDDTYCGCPQCAQAVWDTLACDDAVEDGCHTCGSRISWLQSNNGGNIDNACHMVASQFPSGPCGVCNPDTCNVTAEPTKCPSLPPTPKPTPLSTLAPTPNPIKVSTQAPTSTPDDTYCGCPQCTQAVWDTLACDDSLGGCHTCGSRISWLQSNNGGDTDETCKTVSEQFSNGPCGFCNPLLCNNPVLDDPDPTKLIWSDEFNVDGTPDPSKWSYDIGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG14</accession>
    <name>A0AAD9DG14_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Queuine tRNA-ribosyltransferase</fullName>
            <ecNumber evidence="3">2.4.2.29</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003736</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.29" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DG14"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="entry name" value="Queuine tRNA-ribosyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050852">
        <property type="entry name" value="Queuine_tRNA-ribosyltrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46064">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46064:SF1">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="tRNA-guanine transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="tRNA-guanine(15) transglycosylase-like" evidence="2">
        <location>
            <begin position="404"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="575" mass="64488" checksum="EC78D769B9CEABD2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG38</accession>
    <name>A0AAD9DG38_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Zinc-binding dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004846</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DG38"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43189:SF1">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C1198.01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43189">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C1198.01-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="2">
        <location>
            <begin position="1"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="339" mass="36617" checksum="98062DFE6FB1047F" modified="2024-05-29" version="1">MYYTPAPKEPEDVIIQVEASTVTVRDCLLCRGIGIDKARYPFTPGCEIVGTIADLGGKAKLEGWRIGDRVVAFDHTKGGGNAKSAKVHMGNISMISTTIDAASAACLVDVYMSAYKALRLGKKDGMPLTGRKILITDGFSPIGQAVVALAKLEGANIFVTASDSSEQEYMSSLGVKCFPLSPTKWLHKVAGKMDVVIDNTCIDSYESSWEAVSPEGVLVCTTGMTSTLNFRHDEFGEGCASGCADAFGLNIPKYRSKWAAMKAKYLMSNTQFLDLTECLTTDPKGYQQELKYLCFLVESGALVPKVAERIQIEEVADAHRYLETGKSNGTIVCVPNDNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG69</accession>
    <name>A0AAD9DG69_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ubiquinone biosynthesis monooxygenase COQ6</fullName>
            <ecNumber evidence="2">1.14.13.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003966</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DG69"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051205">
        <property type="entry name" value="UbiH/COQ6_monooxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43876">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43876:SF7">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="FAD-binding" evidence="1">
        <location>
            <begin position="263"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="1">
        <location>
            <begin position="461"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="606" mass="65212" checksum="DE854FF472B653EE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG96</accession>
    <name>A0AAD9DG96_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sel1-like repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_002689</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DG96"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="17"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="82"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1746082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="304" mass="34436" checksum="663191E7CBC8ED0B" modified="2024-05-29" version="1">MSSEADAIIDFDDKKCCASCGIAANDDVKLKNCTACHLVKYCGVKCQREHRSKHKRECKKRAAELHDEILFKQPESSHHGDCPICCLPLSLDEQKSGMMTCCSKQICKGCCYANAMREIRESLEQKCPFCRHPLQSKDEDFGQNLMRRAEANDPVAMREMGKRRRNEGDYGKAFGYWKKAAELGDSEAHFQISVFYRDGKGVEKDVKKAIYHAEQAAIGGHPRARFNLGYEELRNRRIERAMKHLIIAANLGHDVSLRSLREHINIFVSEEDFAAALRAHQAALDATKSPQRVAGEAFYAKHQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGF7</accession>
    <name>A0AAD9DGF7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002884</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGF7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="573" mass="64533" checksum="A1E292043B07004A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGX6</accession>
    <name>A0AAD9DGX6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002131</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGX6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="205"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="276" mass="30837" checksum="480F619839A2AD38" modified="2024-05-29" version="1">MTSIQSNGTVRSKSDKHSKRRESSSSSTTTRIIILGGRSQHSLPTTEGNGMKIDRAHQPTIQQEPIFTITQWNTFCDTINTSLQIYNIVIQTHSKKVVSRLLILPMAASTLITVILIIFGRPFVGLGIFAATLASSLMVCLYDRYRVDRAYDGAIGNLKKVVEKINEEGVLLEDCGVVLSVVLTGPTSSSRNDDEDDNDNHVDQDNNSSSNNNNNSSEKRRNNITNVYIECKRIGISDSPLHRDDDDESLERRQKQQRKAIKNNIVYNEEDASFSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHW9</accession>
    <name>A0AAD9DHW9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_002058</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHW9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049804">
        <property type="entry name" value="Choice_anch_L"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF038133">
        <property type="entry name" value="choice_anch_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042110680" evidence="3">
        <location>
            <begin position="19"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="312"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1746714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="435" mass="46640" checksum="7D138D9C9F7B037C" modified="2024-05-29" version="1">MNLSLALLATSFAVAADAITFSSLSAQELVENYFSNPEDPVEFRNVAASDHSCFALFANGHSAGRHSLSNNFLLPNDGIIMSTGKPEDFHINDSDETTTDFGIETGDIHLEHNVAQGTQVLDPCFIQFEFSCPETTDIYTPQNTCKEEKEEDVDNKELINRGSHNDAIGFFLNGQNIALVPDENGGVAAVSIEDVNEKRNTQYFIDNKSKNSTSVYSEVDADGFTTKLTAQGEAKPGWNIIKLAIGDVGDGNLDSWVLLEAGTFSCALGDAPKSFQPPATVDVEAVEVTEAKEPIVASGESESAPPQKMSGVAVFFILVVVIVVVGWILLASGALKVNKVSNGKITAALGKPNAGQMKAKSIEMYGTIKAKSIEMYGTIKAKSIETFGKVKAKSNEKFGSKKVNPTDESVAAPSKPVEQVIEQPVEEIDETDSNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHY9</accession>
    <name>A0AAD9DHY9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002885</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHY9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="271" mass="29874" checksum="A4D6A462306C90D9" modified="2024-05-29" version="1">MAGHAVLRSQITQNAESDQIHPEHHNPLDGVIKSIFAFGDAMVDEFVSAFVEQIMMERAKLAGYTMRAPFLISEHPHEHHERRGQREKDVKYTLTLSPDLNDSIHVLSVTLTACQIAAAKVNSVDSRTAEMMYFGSRSIENSLSHAVGCKFLDIGLDPMGMCPEIYLDGAKQFCHDVCAFKRFFQHITSSEGPMERAVAASRLMSLDESPLTALRNALCALISSDTGSEALFISDFAADSRLLEEAESMLDAKGFGSLALEEAVSIMNRRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIC1</accession>
    <name>A0AAD9DIC1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">SND2/TMEM208 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_000855</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM208 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIC1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006624">
        <property type="term" value="P:vacuolar protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008506">
        <property type="entry name" value="SND2/TMEM208"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13505">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13505:SF7">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05620">
        <property type="entry name" value="TMEM208_SND2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="125"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="152"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="153"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="174"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1748916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="185" mass="20296" checksum="AE104F51EE68BE1F" modified="2024-05-29" version="1">MLPYPQQLLCILSINMANAAAKKAAAARQSASSTYLPIVAALNLLYVILIATYKRASLTTFQCIMVVTLVGLSYLSYRGVVDNHANQDFKNNKKADDALAGGAFLDMLGLVSVVQFGSVLFSDKFYWLLLLIPTVGGWKLYSTVKGGLPGMPNATSAAASSDNEQVSEKDNEKRQKRAERRRRKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIJ1</accession>
    <name>A0AAD9DIJ1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Heme-dependent peroxidase</fullName>
            <ecNumber evidence="10">1.11.1.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_001397</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the peroxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.7" evidence="10"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140825">
        <property type="term" value="F:lactoperoxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00314">
        <property type="entry name" value="plant_peroxidase_like"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF36">
        <property type="entry name" value="L-ASCORBATE PEROXIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 10" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042168495" evidence="8">
        <location>
            <begin position="20"/>
            <end position="2709"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="9">
        <location>
            <begin position="100"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="9">
        <location>
            <begin position="434"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="9">
        <location>
            <begin position="768"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="9">
        <location>
            <begin position="1118"/>
            <end position="1426"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="9">
        <location>
            <begin position="1505"/>
            <end position="1813"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="9">
        <location>
            <begin position="1891"/>
            <end position="2162"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="9">
        <location>
            <begin position="2241"/>
            <end position="2541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="370"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="704"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1036"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1423"/>
            <end position="1470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1810"/>
            <end position="1856"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2159"/>
            <end position="2206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2538"/>
            <end position="2620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="376"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="710"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1044"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1431"/>
            <end position="1465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1810"/>
            <end position="1851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="2167"/>
            <end position="2201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="2552"/>
            <end position="2581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="2590"/>
            <end position="2620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1747434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2709" mass="293685" checksum="24DF545547993067" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJD4</accession>
    <name>A0AAD9DJD4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integrator complex subunit 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJD4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032039">
        <property type="term" value="C:integrator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034472">
        <property type="term" value="P:snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051113">
        <property type="entry name" value="Integrator_subunit6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12957">
        <property type="entry name" value="DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12957:SF2">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="589"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="677"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="722"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="741"/>
            <end position="757"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="813" mass="89545" checksum="4EBD04D06E16D7D1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2LIT2</accession>
    <name>A0A7S2LIT2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004958</name>
        <name evidence="1" type="ORF">SMAR0320_LOCUS12581</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="HBGZ01017535">
        <property type="protein sequence ID" value="CAD9607532.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S2LIT2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CAD9607532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="156" mass="18408" checksum="C3E7B1514CAA0A30" modified="2021-06-02" version="1">MPSPENTNPMHVKLSMKRERGRGAKQLTKEELNRRAVRFSTSQTRIMTYDAEIYSRRNLVWYEAADLRQFKQNRMVDASRIKNKEYSENGEKICWWGLERFIVPSVRSKTMRAREQVKQVVLCKQEKACQDRQLKKSSDWAAESAQARAAYYSSHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XR56</accession>
    <name>A0AAD8XR56_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein S11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_017105</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="mitochondrion" evidence="4"/>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000083">
        <property type="protein sequence ID" value="KAK1732064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XR56"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="entry name" value="Ribosomal protein S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_uS11_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1732064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="202" mass="24239" checksum="FE2279C358AB786E" modified="2024-05-29" version="1">MLSLKIANKSFFSSNLINQNYFKHLFSKIKILKFIKKETFSFYLSWLILFTFTKLYHIKTKINYFTAYILFSFFTHQKLISYVINVNLSLTNTLINVNDIKGNPKFFYSAGMFNLQKTQKVRQPKAIITILKSLLVKIKVFRTKPVALHFNNLFFNHQSYIYKKLKRKIFIKLVTSYNYHPHNGCRLKKKKRIKIRTRTKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRD5</accession>
    <name>A0AAD8XRD5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Replicative DNA helicase</fullName>
            <ecNumber evidence="11">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_017227</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="13"/>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The main replicative DNA helicase, it participates in initiation and elongation during chromosome replication. Travels ahead of the DNA replisome, separating dsDNA into templates for DNA synthesis. A processive ATP-dependent 5'-3' DNA helicase it has DNA-dependent ATPase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the helicase family. DnaB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="11"/>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRD5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00984">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001761">
        <property type="entry name" value="Replicative DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.860.10">
        <property type="entry name" value="DNAb Helicase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036185">
        <property type="entry name" value="DNA_heli_DnaB-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007692">
        <property type="entry name" value="DNA_helicase_DnaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007693">
        <property type="entry name" value="DNA_helicase_DnaB-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016136">
        <property type="entry name" value="DNA_helicase_N/primase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00665">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30153:SF2">
        <property type="entry name" value="REPLICATIVE DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30153">
        <property type="entry name" value="REPLICATIVE DNA HELICASE DNAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00772">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03796">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48024">
        <property type="entry name" value="N-terminal domain of DnaB helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="3 11" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 11 13" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0934">Plastid</keyword>
    <keyword evidence="2 11" id="KW-0639">Primosome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SF4 helicase" evidence="12">
        <location>
            <begin position="185"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1732184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="455" mass="52551" checksum="D64411C37FB4994A" modified="2024-05-29" version="1">MKNFDNKVQFSLPKTPLPHNFVAEKIVLSCLLINYEAIEITMKTVQAETFYFINHQEIYKAIIEMYRKKVPINVFSVNDFLKETGCLNKIGGTKVLLELLNQIPNLVYLEEYIQLIQDKFLRRTLINLGYEAINSAYITNIPLEKILNDFEKKSFALTNELTKEKQFTTAELFSTVFLELKQKALNPNLPGIASGFYDLDSLTQGFQKSDLIILAGRPSMGKTAFVLNLTENILKQYKLPIVFFSLEMSKEQLIYRLLSNETGISQTRLKLGNLYKEDWYQLKKSIQEYSQLPFFIDDQPNLTTLNIRSRIKKILFEQNKIGLIIIDYLQLLLSSKSKSENRVQEISQITRTLKNIAKEFQIPIIALSQLSRNVESRVNKRPVLSDLRESGSIEQDADLVLMLYRENYYNSTIKKNENITPAELIIAKHRNGPLGIVDLLFQDDPTKFFNTLPNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRT1</accession>
    <name>A0AAD8XRT1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF285 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016628</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000061">
        <property type="protein sequence ID" value="KAK1732651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRT1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005046">
        <property type="entry name" value="DUF285"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011889">
        <property type="entry name" value="Liste_lipo_26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056866">
        <property type="entry name" value="Znf_WRKY19"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02167">
        <property type="entry name" value="Liste_lipo_26"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03382">
        <property type="entry name" value="DUF285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24906">
        <property type="entry name" value="Zf_WRKY19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="1">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="691" mass="75983" checksum="B53E022B0A89B4B8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XS78</accession>
    <name>A0AAD8XS78_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Adaptin ear-binding coat-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016755</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000064">
        <property type="protein sequence ID" value="KAK1732543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XS78"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030125">
        <property type="term" value="C:clathrin vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13228">
        <property type="entry name" value="PHear_NECAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012466">
        <property type="entry name" value="NECAP_PHear"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12847">
        <property type="entry name" value="ATP-BINDING CASSETTE ABC TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12847:SF9">
        <property type="entry name" value="NECAP-LIKE PROTEIN CG9132"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07933">
        <property type="entry name" value="DUF1681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NECAP PHear" evidence="2">
        <location>
            <begin position="7"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="215" mass="23478" checksum="D9009671A8C0A55A" modified="2024-05-29" version="1">MADEVVIERLRLKIPNAHIFKLPPKPSAGGWRGGDWKDKIWQGSLKVVERNDNTAVLLVDAQEENNIFAVCPINHQLDERANNGGNGVDRCIDSSRYFVLRIQNAQGRHMFIGLAFNERNDAFDFNTALEDSRREKVAEKKAAAAPSLGNSRVNSVDYKMKEGEKIKVSIGIGRSSGGGDGGAAAKRRLEKARSSNTGSGGFLKPSSKDTPSRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSR1</accession>
    <name>A0AAD8XSR1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_016427</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSR1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1732889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="258" mass="29057" checksum="47B00FD3075C1DC9" modified="2024-05-29" version="1">MESADPEERQKESSLVERESSMCSWGIPSNETLLFTAFVSFMGFATVQTVVAFIAQSDAMLGDSAAMAVDALTYGFNLYAEREKTQDVVADENNEDEIADNFELSSSDKRNTTTFDESEGETERDRLEQQFLKRRRHLHLELVPPLMSVSILIIVTIFVLRNSIKTLILDTHRNESEQTQPNLKIMMAFSTANLFLDLFNVTCFATAKHLMGYNTTEQSNTEQHYGEVIDDEVYSGLNADDNESGVDPEETEEEKGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSU9</accession>
    <name>A0AAD8XSU9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pentatricopeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_016383</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSU9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051222">
        <property type="entry name" value="PPR/CCM1_RNA-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47942:SF63">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47942">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT (TPR)-LIKE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042085901" evidence="3">
        <location>
            <begin position="19"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="504"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="539"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1732845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="719" mass="77081" checksum="88DDC22C08652801" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUW8</accession>
    <name>A0AAD8XUW8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015484</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUW8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="280" mass="31999" checksum="4A0F97C43FAAA06C" modified="2024-05-29" version="1">MHDRVRIIEKNAFDDCVQLKSIKLLGVRVIKDYAFVGTMQLHGVEFGEELHTIGHMAFAHSSLEYVKLPKVRVLNSSAFYACEKLVEAHLSEDLETIERFVFARCPHLERISLPLRPNIFQDHSVFNVYDDEQDLLDNDNGIYNRHALSRVDLVGGIHSTIASLHMVSWRNEMNNEINRINQVLPNIAGDTKTQVIQQWMRTVIGRLAHCKDEHHKLLKEATTLLELALWKANLDNNEQLEIEGVRTTRGRLKRARKESCVTSGASTVIKNVLPFLALKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVQ6</accession>
    <name>A0AAD8XVQ6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014882</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="77"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1335"/>
            <end position="1354"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="174"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="336"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="462"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="557"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="971"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1087"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1344"/>
            <end position="1354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1812" mass="204812" checksum="F5B0DCE5576CBCCB" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVT4</accession>
    <name>A0AAD8XVT4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVT4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1244" mass="135914" checksum="C132DCD238308EC7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWE2</accession>
    <name>A0AAD8XWE2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014553</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWE2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="243" mass="26541" checksum="B4165CC4CEB2B92E" modified="2024-05-29" version="1">MVEPKNTPSTATGVAASSSVEKAAATAFARLQSEETDATSTSKIKTSLHNADVEYARKRKRIEEQIDSETRQLLQSLEWKKSQLLNAAKSEHKQLKTSILQSVDPSSSSAGNCTICNAPMTKIAAAQCIGEGCNGAFCKSCLKHKIGDNVRCHCCSDVVNVMCPSCVDAMNAKRGWYQFDYCKNDCGFICPEHSWKEDCCVCGECHLCSPAIRGKCSLSECGRCGEKLCDRCDYKEGCMCVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWE6</accession>
    <name>A0AAD8XWE6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA2/NAM7 family helicase</fullName>
            <ecNumber evidence="8">3.6.4.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_014623</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWE6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016604">
        <property type="term" value="C:nuclear body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001147">
        <property type="term" value="F:transcription termination site sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006369">
        <property type="term" value="P:termination of RNA polymerase II transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000326">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF495">
        <property type="entry name" value="HELICASE SENATAXIN ISOFORM X1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="6">
        <location>
            <begin position="427"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="7">
        <location>
            <begin position="729"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1734750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="951" mass="106095" checksum="42F9B33F0A59A040" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWJ5</accession>
    <name>A0AAD8XWJ5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CAP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_014438</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWJ5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33683">
        <property type="entry name" value="1, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33683:SF46">
        <property type="entry name" value="SUSHI DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="3">
        <location>
            <begin position="545"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="136"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="317"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1734978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="725" mass="78881" checksum="220ACC5DE5391C15" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XX35</accession>
    <name>A0AAD8XX35_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014356</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XX35"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="551" mass="61930" checksum="11F79C85657B6BF3" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXD2</accession>
    <name>A0AAD8XXD2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cell cycle checkpoint control protein RAD9A</fullName>
            <ecNumber evidence="2">3.1.11.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.2" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXD2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030896">
        <property type="term" value="C:checkpoint clamp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008311">
        <property type="term" value="F:double-stranded DNA 3'-5' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071479">
        <property type="term" value="P:cellular response to ionizing radiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000076">
        <property type="term" value="P:DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046938">
        <property type="entry name" value="DNA_clamp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007268">
        <property type="entry name" value="Rad9/Ddc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15237:SF0">
        <property type="entry name" value="CELL CYCLE CHECKPOINT CONTROL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15237">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04139">
        <property type="entry name" value="Rad9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55979">
        <property type="entry name" value="DNA clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="511" mass="56186" checksum="5DA92B376A5ABFEF" modified="2024-05-29" version="1">MDITIPPHNLKRFTAAITCLGKIGKDLYLSFDPLDGLVLSSLNEAKSAFGKFHFDSTFFDRCSAPAVVVSASRSSASASSFLGRGRNTNGGGSNNTNNHNSEEDEDDEDFYDSSRYVCRVPVRSVHSVLRPRKGVCHLRIRSEGTDDSGNHFGLKNGKRRRRRNNRQQPRRDEGVGHEEGGDDNNDEQEEERRPYSSSARRRKKRRSNKKNNSDNNNNTAGNDKQSSSAAEKGNDKMMLSFEFVIERTAPNQNRNNNVMEGVNSSSTGGTFRVLHKVGVTDANGITLSASTRKRDRSEIVSPPKLWLRLLDPLRRTAEVALTVDDELKVVTATSFHPVEMQGGGVGGGGGNGSEENAVLQAAAAKAAVLKTETSTGTEEFDEYDFRNNRGRKKKRRRRGNDDDDEDSDDDDNNEDDEERAGDKAPPDVNQKVILVFSIKEAKAMLQFCAQTNSTFHDDGDALSILSFHWGGKPIVIETDGDSFSGELVLATLHHGMIASNITVGGRRESSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZ44</accession>
    <name>A0AAD8XZ44_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sulfotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000031">
        <property type="protein sequence ID" value="KAK1735946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZ44"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005331">
        <property type="entry name" value="Sulfotransferase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03567">
        <property type="entry name" value="Sulfotransfer_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="525" mass="60042" checksum="5E20A578446AEBB1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZM8</accession>
    <name>A0AAD8XZM8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Structural maintenance of chromosomes protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_013352</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SMC family. SMC5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZM8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45916">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45916:SF1">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecF/RecN/SMC N-terminal" evidence="6">
        <location>
            <begin position="20"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="388"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="717"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="786"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="412"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="717"/>
            <end position="736"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1736216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1123" mass="129297" checksum="4497E9BA12D2FC99" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y015</accession>
    <name>A0AAD8Y015_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012506</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1737061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y015"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="398" mass="44144" checksum="1BD2BC6C16445185" modified="2024-05-29" version="1">MSSNKQANTHSIKPAHRMQDPAYDEAEHSVCDSSSRQLPKQPQHCSLIHRQLNSPVTSPALPDLRESMNLKKRSSSGLPIHSATHTNNTSDATIAAEIGHTSAILSSNPVAKRKRVSFCGSTKEASANNNLSTTPLGLRKLENQLPTSIMNQSRSCTALPGLSVSASVEIDSALVSTSELDLNVSPATFVRTILLQSCSIRGEDIISVATKRLNDDSYFLTYSDEQTEAYNNEKVFAVQGNDVEALRASHKAGELMQTSNRFGESLLHTSCRRGFTEMVRFFINEAGVSPRVRDDMGRTPMHDACWSSSAPNHEIMRILITSAPEMLLSKDKRGHSPFDYARREYWPQWVQFLNEHRQLIVNCLLASFLESPENIITLDDSDTSRSSPTDEMAHVWQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y054</accession>
    <name>A0AAD8Y054_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012637</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y054"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1736615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="128" mass="14609" checksum="159FC6FEE58AB4CB" modified="2024-05-29" version="1">MKQKKDDFIRRGDKATTAITIIVFESIIERVKWTEEQCNSVPEHHVDTLTTSLKKATDLPPLPEGGVAAALKKWMDSEHDNNNDNDDNVYPTCYLPPPKSCDVTSYTLVIMSHTTERLEAFMDPLRTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y079</accession>
    <name>A0AAD8Y079_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Exosome complex component RRP4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_012780</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRP4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y079"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071034">
        <property type="term" value="P:CUT catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22525">
        <property type="entry name" value="KH-I_Rrp4_eukar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05789">
        <property type="entry name" value="S1_Rrp4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026699">
        <property type="entry name" value="Exosome_RNA_bind1/RRP40/RRP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048565">
        <property type="entry name" value="S1_RRP4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21321:SF4">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21321">
        <property type="entry name" value="PNAS-3 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15985">
        <property type="entry name" value="KH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21266">
        <property type="entry name" value="S1_RRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0271">Exosome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRP4 S1" evidence="7">
        <location>
            <begin position="132"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="6">
        <location>
            <begin position="236"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="40"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="84"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF15985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF21266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1736758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="389" mass="42486" checksum="7C67A6E8513063C8" modified="2024-05-29" version="1">MAADSLHHHFVLPGQVLATSMSESEGGFLRGHGTYIELVPDESTDHNDDDMCDTKQQGGMAGTSKKKRSGWGTETKSTVMQMDDGNEAEKQDENDEPSDFQRGPQRLIASVAGTVERVNKLISVIPLSPSIYTGQVGDLIVGRIVGVGGSRWKVSLTCSPPTASASNGSMKEGQLPLSGVNLPGGVQRIRTSEDVLAMRNLFREGDLLTCEVQQVQKDGNLILHTRSLRYGKLDNGVLVTVPPSLVGRRKNHFVTLKGLTSQNSDAMDTEEGGEGDVDVYLGLNGGIWIQRTIPSEWENAIRADQDERAPLAETLQKLRHRHSTTRVSPSMRESIARVRNSVECLRLVHCQITPDSIEIVARASVDQGVRVADMLLPEMVIKLTEGTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y101</accession>
    <name>A0AAD8Y101_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DnaJ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_012030</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y101"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051727">
        <property type="entry name" value="DnaJ_C3_Co-chaperones"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44140">
        <property type="entry name" value="LD25575P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44140:SF2">
        <property type="entry name" value="LD25575P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14608">
        <property type="entry name" value="zf-CCCH_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="J" evidence="5">
        <location>
            <begin position="968"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="66"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="625"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="872"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="66"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="140"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="194"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="208"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="227"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="639"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="658"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="872"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="897"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1737163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1047" mass="115132" checksum="56215229950E33FF" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1V6</accession>
    <name>A0AAD8Y1V6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012193</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="AlphaFoldDB" id="A0AAD8Y1V6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="239" mass="26842" checksum="5219B3E3D8EF7326" modified="2024-05-29" version="1">MAITKSLRWVPMRSISVAKTNTEGDKNLSDKAASNMEKESRHTAEDIDTTIIAVREKEEETVSMHSIFGNLFHCWGAYEMRETTGAYAPAQLEIETRLKESRKQALEQIEAKLRKQEEEERAQRLIEKFKMNMKLLEAKKAAEAKNQAEHEASQAIEIDISKDLMKTLQAKEKALRALEAKKAAEAKKQAAAEAKKAAKAEKLAQKDVKEASESKKHATAETKEATEDEKLAQKDAKEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1W5</accession>
    <name>A0AAD8Y1W5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein transport protein sec16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_011460</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the SEC16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070973">
        <property type="term" value="P:protein localization to endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="ACE1-Sec16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="WW"/>
        <property type="match status" value="10"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024340">
        <property type="entry name" value="Sec16_CCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024298">
        <property type="entry name" value="Sec16_Sec23-bd"/>
    </dbReference>
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        <property type="entry name" value="WW_dom"/>
    </dbReference>
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        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13402:SF6">
        <property type="entry name" value="SECRETORY 16, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Sec16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12931">
        <property type="entry name" value="TPR_Sec16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
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        <property type="match status" value="13"/>
    </dbReference>
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        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="13"/>
    </dbReference>
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        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="13"/>
    </dbReference>
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        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="13"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="5 6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
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            <end position="106"/>
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    </feature>
    <feature type="domain" description="WW" evidence="8">
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    <feature type="domain" description="WW" evidence="8">
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    <feature type="domain" description="WW" evidence="8">
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    <feature type="domain" description="WW" evidence="8">
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    <feature type="domain" description="WW" evidence="8">
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    <feature type="domain" description="WW" evidence="8">
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    <feature type="domain" description="WW" evidence="8">
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        </location>
    </feature>
    <feature type="domain" description="WW" evidence="8">
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            <end position="1831"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="8">
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            <end position="1919"/>
        </location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
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    <feature type="region of interest" description="Disordered" evidence="7">
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    <feature type="region of interest" description="Disordered" evidence="7">
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    <feature type="region of interest" description="Disordered" evidence="7">
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
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        </location>
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    <feature type="region of interest" description="Disordered" evidence="7">
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        <source>
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    <evidence type="ECO:0000256" key="3">
        <source>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
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    <evidence type="ECO:0000256" key="7">
        <source>
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            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
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    <sequence length="2678" mass="288401" checksum="1B6DFE1607AB7851" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y248</accession>
    <name>A0AAD8Y248_9STRA</name>
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        <recommendedName>
            <fullName evidence="3">Sulfotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
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            <taxon>Thalassiosirophycidae</taxon>
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            <taxon>Skeletonemataceae</taxon>
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            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
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    </organism>
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        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y248"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1738219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="445" mass="50652" checksum="88BF03354A2AFF60" modified="2024-05-29" version="1">MNSTTRQLASSLSSRWMKAAVTVVILALSLFSIFTQKALLSRGKNSSPAASFALTTTTKSKDPSARHQLSSNANIRNFVLHIGPAKTGTTTIQKQIVQSDEVRSKLLLDNYGVIDHNIIHQPTVASINIDSSYNFSDKILVVIEKLKSKRTNNNIFGSSEYLYRKFPRSDKGCSSLKRNLLGIMTKGNEHWKLHIVFTYRRLYDVWPSHWNQMFKFHRNKNGIAVGLNTDWPEDGGNRIPPFGEWIYQYLDNYESKEADLRAYNAWKSCSDDITVVNFHDTKVYLPNGTGPVEVDLATKFACKGIIGASHTCSFLLQQENLQEKHNPSVNHGPDMLAVHAHESGLISPGWKREKVTGKIKRYVASKNPEISSLPMRCPNATTLQRMYDCSLKFQKSVLVAENMTQQMLDFDLGWKQALEQQKFCTWDVKDIVKRKEWKQFFSQSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y258</accession>
    <name>A0AAD8Y258_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011631</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000024">
        <property type="protein sequence ID" value="KAK1737647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y258"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="217" mass="24541" checksum="4B9FC5C4A61AD875" modified="2024-05-29" version="1" fragment="single">SNKLQGHDVVILYIAVFSPSVLSLVVAVKKKKRTLSRYCSILIGKEQKLCSAHIIIGVTPRSSHSQSKMGFTDFLRNFHEKHEKLKHTIHNKWRYPLPKSGQYAMALFYFCIPIVGGHYVMEWAKSKSVDEIGARGEKLREKKLQGFGNKTVIDGKVESIGAGGIGGGVHLALSDEDTQKKNKAMLEAMFKRERKRRRKEKKDSEPKESNVDEEKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2W0</accession>
    <name>A0AAD8Y2W0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011582</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2W0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="68" mass="7330" checksum="9992F0C9C7772B5E" modified="2024-05-29" version="1">MPMFKKPVTSSSPAKGDNTAKPPAGKDTKRRPSRRKSSGTKDSAGNLRRSSLMCDMMTGDLLADSDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y308</accession>
    <name>A0AAD8Y308_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">GTPase Era family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_010744</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y308"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043024">
        <property type="term" value="F:ribosomal small subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04163">
        <property type="entry name" value="Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22534">
        <property type="entry name" value="KH-II_Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.20:FF:000003">
        <property type="entry name" value="GTPase Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00367">
        <property type="entry name" value="GTPase_Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030388">
        <property type="entry name" value="G_ERA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005662">
        <property type="entry name" value="GTPase_Era-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42698">
        <property type="entry name" value="GTPASE ERA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42698:SF2">
        <property type="entry name" value="GTPASE ERA-LIKE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="Prokaryotic type KH domain (KH-domain type II)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042129635" evidence="7">
        <location>
            <begin position="23"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="KH type-2" evidence="8">
        <location>
            <begin position="420"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="107"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="116"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1738714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="514" mass="56660" checksum="F614263F8191EB78" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y480</accession>
    <name>A0AAD8Y480_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine-protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011034</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="1171"/>
            <end position="1608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="433"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="529"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="853"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="273"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="345"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="433"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="531"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="567"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="867"/>
            <end position="880"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1633" mass="180342" checksum="8AC2C9FFA9B5F1A2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4A8</accession>
    <name>A0AAD8Y4A8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Cellulase</fullName>
            <ecNumber evidence="3 9">3.2.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_009760</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 45 (cellulase K) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.4" evidence="3 9"/>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4A8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007112">
        <property type="entry name" value="Expansin/allergen_DPBB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000334">
        <property type="entry name" value="Glyco_hydro_45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50842">
        <property type="entry name" value="EXPANSIN_EG45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01140">
        <property type="entry name" value="GLYCOSYL_HYDROL_F45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042029941" description="Cellulase" evidence="11">
        <location>
            <begin position="22"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="Expansin-like EG45" evidence="12">
        <location>
            <begin position="216"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="120"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="376"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1739217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="499" mass="51812" checksum="28031CFA4B3BBF95" modified="2024-05-29" version="1">MTTKLSAARLFISFSISGVSAGGGYCNWGPQGTASSSTCERKGDGSHVQGGTSCNQSQGNCQGCGGRWCTNDIGYCNWGPAGTAASSTCDGDVQGGDYCNVGPSNCQVGCGGNWCETWEDPSGPTPPPTPSPPSPTPPPPTPPTGGNTATTTRYWDCSGGSCACSFIPTGLGTAEPVHCHSNAMFVAPSGNQFGAAYYGAAAISEALGGGNWMSSGCGKCWKVTGYSPITALSTTLVLKGTNFCPPVNAPCSNGKAHFDIAAPGFDVTEFSLSNTCSEREPEEATGFAACGGWMINSQNPNENCNCDAFTDPVLKAGCNNFYNLKWDNPQVHYEEVDCPNELAELHCDYPYATESNMPETCSNNLFTGTTSSATTTATTTATTTSTAQTTSSTSTTTTTTNTTPQTTTTTTSSTTTTTQPPNGSSCCSHDYSTCSSSDWCNASSDNCLDSCSGKAWIEPDSTCIPLYGECTQNRGGCCNPLGNVACKRQSNNYRQCLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5K2</accession>
    <name>A0AAD8Y5K2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_010371</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5K2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="entry name" value="Integrin alpha, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36220:SF1">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX COMPONENT C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36220">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14312">
        <property type="entry name" value="FG-GAP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="420"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="158"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="372"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="181"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="193"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="204"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="281"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="382"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1739055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="804" mass="84980" checksum="2CC95A11A6AC975B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5S5</accession>
    <name>A0AAD8Y5S5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SIMPL domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010062</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5S5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.170">
        <property type="entry name" value="Protein of unknown function (DUF541), domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2970">
        <property type="entry name" value="Protein of unknown function (DUF541), domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052022">
        <property type="entry name" value="26kDa_periplasmic_antigen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007497">
        <property type="entry name" value="SIMPL/DUF541"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34387">
        <property type="entry name" value="SLR1258 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34387:SF2">
        <property type="entry name" value="SLR1258 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04402">
        <property type="entry name" value="SIMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041919052" evidence="1">
        <location>
            <begin position="34"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="275" mass="30186" checksum="CDF749AB3D515292" modified="2024-05-29" version="1">MVGAYCMKVFDMNQHKLFQILVLSFVLLPLAGSASSSATATACNGQLKDHPPSPAIISVRGEGTVSAAPDTATITLGVTSDGKTARDALNRNNQEMDRIMKQLKLLHFQDKDIQTSSLRLHPRYNYDRQGESEKVKGYRASSHLTIRVRDIEKTGSVLDKAVSMGINHVIDNICFSISDPKDILQKARRKAVHDAKTKAETIVSELGCRLGRISCISTESGHSYPMPPMQMQHGSRSVGFSQHSTSPLPTIATGENSYKVSVDITWEIIQTTIEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y600</accession>
    <name>A0AAD8Y600_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_009253</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y600"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="26"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1740303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="282" mass="31816" checksum="08223175B5323DBE" modified="2024-05-29" version="1">MPFDKEFSRPLDTMLIDAYKLTGCFNWHCRAPNPSKRCGKCGVAVYCSRTCQIADWKDKDDPHKHLCQLYCNNTNPKDWKGAKGQQFPVPVGLRGIGLMLEDDLWEAMKNRASLFFDEVSRVIEANRESYREKEIGLILNVMYNFDKPILQGAVTFHDSNGPTLNGGTECVYYILFEPVGEGGEDVRRRIHPATGSGDLSVELRRGAIEVLKEFIQKVNEHGLHINLLTYQRGLMWMSDDDFRNGAAKELEEANGGNRIEWTPDVGYDIEDSLLAASTAAFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6E4</accession>
    <name>A0AAD8Y6E4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-CH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_008993</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6E4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-CH-type" evidence="4">
        <location>
            <begin position="29"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1740043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="443" mass="49395" checksum="BAB37A4F05520D36" modified="2024-05-29" version="1">MNPSKKAYSIPQDMMEIEPTGTQAQAAQDDTSSSSCCWLCLGEGPDASGMPLVRNCSCRGSSGFAHLSCIIRYAEIDGRNSYQSMGNIGAAFQECPNCKQEFQNDLRYHLERARVSFVEREFSDDHMLYLRALIHRVRVLNAENDADKAEGDQICFKMVSIIDEMKSDHSESEWSGEFMKMEAVVMYVIGLFHMNVGSEESLQEALEYFGSAIYLFTLLGDEINIISAKKNIAKIEAKFSGEEISHDEGNDLEFSKRQYKYWLGKLGEQHPITIRRGELLAHALYCSNQGVAAERLLAKMTAISRQVHGPTHNCTLSATSALKDVKDRRVFIDSRRQWFHALKYENDGLSCVVRGPVVESAGGSSSSMQEEHMLTLSLPITDVFPGPGTPVVCQGLSERAHLNGKIGDTRGFNGGKFEVHFEEAGLEPAIIKHENLRIVFELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6Q0</accession>
    <name>A0AAD8Y6Q0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ELMO domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008979</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6Q0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006816">
        <property type="entry name" value="ELMO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050868">
        <property type="entry name" value="ELMO_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12771:SF56">
        <property type="entry name" value="CED-12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12771">
        <property type="entry name" value="ENGULFMENT AND CELL MOTILITY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04727">
        <property type="entry name" value="ELMO_CED12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51335">
        <property type="entry name" value="ELMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELMO" evidence="2">
        <location>
            <begin position="244"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="545"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="577"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="694" mass="74701" checksum="6C5E1615BED05BC8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6R6</accession>
    <name>A0AAD8Y6R6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nucleoside triphosphate pyrophosphatase Maf family protein</fullName>
            <ecNumber evidence="4">3.6.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_008864</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6R6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047429">
        <property type="term" value="F:nucleoside triphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00555">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00528">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003697">
        <property type="entry name" value="Maf-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00172">
        <property type="entry name" value="maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213">
        <property type="entry name" value="BIFUNCTIONAL DTTP/UTP PYROPHOSPHATASE/METHYLTRANSFERASE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213:SF5">
        <property type="entry name" value="BIFUNCTIONAL DTTP_UTP PYROPHOSPHATASE_METHYLTRANSFERASE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02545">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="ITPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042127716" evidence="3">
        <location>
            <begin position="17"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1740769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="285" mass="30938" checksum="D6D7BB9FADABA360" modified="2024-05-29" version="1">MMYTVALSVLITFCGCISNNNSCQGFSLHTSKTAAHRTSMMSASNSDGVAYDEPSKLLVSSFHQISLASDPEAKLRLILASQSPRRTEILEMMGLGGRFTASPSPLDEEKLQIELSQQEISPSDYARTLAERKAHAYAAEALEITNGVALIIGSDTIVDLDGHIMEKPTDEKVAHSMLSSLSGNWHQVHTGVAVYAVGASASSNEPQLMFSFTDTAKVKFASLTDRDIKAYIDTREPFDKAGSYGIQGIGGQLVEKINGDFFTVMGLPMHRLSRELTDVIKNLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y734</accession>
    <name>A0AAD8Y734_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Copine</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_009579</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y734"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071277">
        <property type="term" value="P:cellular response to calcium ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04047">
        <property type="entry name" value="C2B_Copine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037768">
        <property type="entry name" value="C2B_Copine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045052">
        <property type="entry name" value="Copine"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10857:SF106">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10857">
        <property type="entry name" value="COPINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="806"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1043"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="4">
        <location>
            <begin position="46"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="29"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="308"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="721"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="881"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="48"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="320"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="330"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="342"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="354"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="389"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="423"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="461"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="489"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1739820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1068" mass="118275" checksum="FDD2EF14BCA31D11" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7F0</accession>
    <name>A0AAD8Y7F0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoenolpyruvate carboxylase</fullName>
            <ecNumber evidence="2">4.1.1.31</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008648</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.31" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7F0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008964">
        <property type="term" value="F:phosphoenolpyruvate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.90">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021135">
        <property type="entry name" value="PEP_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033129">
        <property type="entry name" value="PEPCASE_His_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30523">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30523:SF6">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00311">
        <property type="entry name" value="PEPcase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00150">
        <property type="entry name" value="PEPCARBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00393">
        <property type="entry name" value="PEPCASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="1">
        <location>
            <position position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="772" mass="85572" checksum="A7418466E9FEA13E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7F7</accession>
    <name>A0AAD8Y7F7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pentatricopeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_008441</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPR family. P subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7F7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050872">
        <property type="entry name" value="PPR_P_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46128">
        <property type="entry name" value="MITOCHONDRIAL GROUP I INTRON SPLICING FACTOR CCM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46128:SF329">
        <property type="entry name" value="MITOCHONDRIAL GROUP I INTRON SPLICING FACTOR DMR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="377"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="50"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="55"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1741189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="779" mass="88622" checksum="79D0FA76A6FD5BB4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7M6</accession>
    <name>A0AAD8Y7M6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008607</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7M6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="407"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="475"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="542"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="483"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="542"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="622"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="690"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="775"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="830"/>
            <end position="843"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="856" mass="91990" checksum="A830F5744D3A43C3" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7S0</accession>
    <name>A0AAD8Y7S0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">GABA-B receptor-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_009261</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7S0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038039">
        <property type="term" value="C:G protein-coupled receptor heterodimeric complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004965">
        <property type="term" value="F:G protein-coupled GABA receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15047">
        <property type="entry name" value="7tmC_GABA-B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001828">
        <property type="entry name" value="ANF_lig-bd_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002455">
        <property type="entry name" value="GPCR3_GABA-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000337">
        <property type="entry name" value="GPCR_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017978">
        <property type="entry name" value="GPCR_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519:SF20">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR 156-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519">
        <property type="entry name" value="GABA-B RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00003">
        <property type="entry name" value="7tm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01094">
        <property type="entry name" value="ANF_receptor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00248">
        <property type="entry name" value="GPCRMGR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50259">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="536"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="571"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="606"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="650"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="708"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="743"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="771"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 3 profile" evidence="11">
        <location>
            <begin position="609"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="801"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="917"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="819"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="927"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="971"/>
            <end position="987"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1740311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="994" mass="107127" checksum="A64C3A68E0C1B927" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7X5</accession>
    <name>A0AAD8Y7X5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Menin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_007919</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7X5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035097">
        <property type="term" value="C:histone methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000403">
        <property type="term" value="F:Y-form DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045786">
        <property type="term" value="P:negative regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008285">
        <property type="term" value="P:negative regulation of cell population proliferation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007747">
        <property type="entry name" value="Menin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12693">
        <property type="entry name" value="MENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12693:SF3">
        <property type="entry name" value="MENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05053">
        <property type="entry name" value="Menin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1741441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="636" mass="71843" checksum="27B76B7A48B184DC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9Z9</accession>
    <name>A0AAD8Y9Z9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EGF-like domain-containing protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006827</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9Z9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="182"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="652" mass="74148" checksum="90FDF2F4F51D2792" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YA90</accession>
    <name>A0AAD8YA90_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006313</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YA90"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="220" mass="24663" checksum="9B6312F6CA183865" modified="2024-05-29" version="1">MMASPQQQADVTSHDKPEATTVAVTAEEDGGVEVVGVSGEKKKIIEDVPPPSFDVSVLPTGRTYNNVECNIKIKPSRKNSPRSQLEFDIKATSGDDDEDRSQQNHSHVAFEIQHKTQAMRDLDGLLADDDVDDEPVRVTFDLDEEEESKKTIKRSNKRKEQRKSPRHSEWLFSCSMDEIDEVVEDIISPFDDITDFMSCATDDSIVMDRIESVCAEGETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAI1</accession>
    <name>A0AAD8YAI1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SGNH hydrolase-type esterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006463</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAI1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00229">
        <property type="entry name" value="SGNH_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051532">
        <property type="entry name" value="Ester_Hydrolysis_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383:SF5">
        <property type="entry name" value="SGNH HYDROLASE-TYPE ESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383">
        <property type="entry name" value="THIOESTERASE 1/PROTEASE 1/LYSOPHOSPHOLIPASE L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="311"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="2">
        <location>
            <begin position="109"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="369" mass="41476" checksum="E07B7A1E5E339F26" modified="2024-05-29" version="1">MNSSSLRQYLRSMNSRHIPPRQGRQGFWDKLLAGFLIAFSPIGVYYAASDNYRNNSNFTTTLVVTGIFGLVVLIAAEGLSRPPHNGPHEFVKQDEKKGKRDEDERVLVCLGDSLTHGACSANWVDDVGPYLTQQLQNKDKTTVKVNVVNAGQNSICTHTVLHEKVYDVVACQPDYIFIMIGTNDAMAIYRDDWAQERMHTWSLTEQPTEDVLIRNLTDTVKSLLDTTTANIAIATLPPFGENIDSDSNKIIQSINCRIKTLEYLFLGEIRNTRRETGRVSVIDVNSALWAEIIRQRSSHNITKTTHSIDKFLPYAIVMGMLHCVFGLSWNLVTRLLTGNAVLSESLHLNENGGCIVTNEVVKWLMDKMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAK8</accession>
    <name>A0AAD8YAK8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006798</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAK8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052058">
        <property type="entry name" value="Alcohol_O-acetyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031641">
        <property type="entry name" value="PapA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037217">
        <property type="entry name" value="Trp/Indoleamine_2_3_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037:SF1">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16911">
        <property type="entry name" value="PapA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140959">
        <property type="entry name" value="Indolic compounds 2,3-dioxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminal" evidence="3">
        <location>
            <begin position="829"/>
            <end position="965"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1742233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1005" mass="111052" checksum="817295004AC52E92" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAQ3</accession>
    <name>A0AAD8YAQ3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ankyrin repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_006858</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAQ3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050663">
        <property type="entry name" value="Ankyrin-SOCS_Box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24193:SF121">
        <property type="entry name" value="ADA2A-CONTAINING COMPLEX COMPONENT 3, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24193">
        <property type="entry name" value="ANKYRIN REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="148"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="4">
        <location>
            <begin position="305"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1742293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="508" mass="57079" checksum="CAC807A708EB19AA" modified="2024-05-29" version="1">MADAPPNSSSLLDLCSLTSSSSTSSINEERQSRLSTLKRWCEEHSTLTNELLTQSDHRDKKTGCMPLHWLAGTGFDEAIEYLLGCSDSDDDTSFSSTALASLSMDQPAHHPSTERTPLHYAARNGHLSTCQLLIEQFGANPHPKCGRGGVTPLQLAVWQNRLDVVQYLIQKNGVHVIHERNDFNCGLMHWIGLIPQKRWCSGSKGDDENAHDDGSGVLPLARYLHSLGISYESTIENSNTQGHTCNHKAAWGGNLPLLKYFRNEHDVYDTIQDAAGNYCADIAKMRGNMECHHWLLEHGSGDRAESYKILGLEVGVAMDVVRNRYLELAKMIHPDKMNQCNIDDDEKKDDIMDDFIKIKQAYEHLTKQNGMGKQKNPKYDELKLLECQKEVKDASGTDDDDDDLFVARLIAVITDYGEKGFPVGLLSRRWNQIWPDRPFPTEYVIERSIKCHAKEGGGGETGKMVIQKRVKLVKWLKYKCRGTKVQFHQTGGEVLAVIDNKKIESVPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBK2</accession>
    <name>A0AAD8YBK2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">cystathionine gamma-lyase</fullName>
            <ecNumber evidence="4">4.4.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Gamma-cystathionase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_007129</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-homocysteine and L-serine: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.1" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBK2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004123">
        <property type="term" value="F:cystathionine gamma-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019343">
        <property type="term" value="P:cysteine biosynthetic process via cystathionine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808:SF15">
        <property type="entry name" value="CYSTATHIONINE GAMMA-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="TRANS-SULFURATION ENZYME FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="5 8 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1742564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="468" mass="50506" checksum="08083C57679B66ED" modified="2024-05-29" version="1">MQSIGRRLWQRCSCRQLSSSSSGRGKVEELSPAKAGSLANQLREKLNNTKNCNESSLSLSTLLSHAGLSSSNGNSNAPLSPPIDLATTYERPADGNYGEGGLIYSRSCNPTRKLLQDAIGQLEVVSQHGQIIAPTFAFSSGMAAVASLLLAQKSPVKVLVPEDIYHGVPTQLHVCLNDHGIVHESVDMTNAYDIRQTIEHHIDSKSNAQHDGALVVWMETPSNPLCQVTDIQSICDLVNDVRCQHQNANIITVVDSTWAPPVITRPLLLGADAVLHSGTKYLGGHSDVLLGTISCSPINETGKFIAERLKSVQTSIGAVASPLECWLTLRGLRSLHVRVERQCQTAMKLANYLDGHEHIAKVHYPGLASHPQHATAKRQMAMYGGMLSFEVKNESMAMAVAGAVSTIRRATSLGGTETLIEHRASIEPPERRTSPPGLLRMSVGLEDADDLIDDLKIALDIASQICDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBM3</accession>
    <name>A0AAD8YBM3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]</fullName>
            <ecNumber evidence="9">1.3.1.88</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_007120</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>5,6-dihydrouridine(16) in tRNA + NAD(+) = uridine(16) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53380"/>
            <dbReference type="Rhea" id="RHEA-COMP:13543"/>
            <dbReference type="Rhea" id="RHEA-COMP:13544"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="12">
            <dbReference type="Rhea" id="RHEA:53382"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>5,6-dihydrouridine(16) in tRNA + NADP(+) = uridine(16) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53376"/>
            <dbReference type="Rhea" id="RHEA-COMP:13543"/>
            <dbReference type="Rhea" id="RHEA-COMP:13544"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:53378"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5,6-dihydrouridine(17) in tRNA + NAD(+) = uridine(17) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53372"/>
            <dbReference type="Rhea" id="RHEA-COMP:13541"/>
            <dbReference type="Rhea" id="RHEA-COMP:13542"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="10">
            <dbReference type="Rhea" id="RHEA:53374"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>5,6-dihydrouridine(17) in tRNA + NADP(+) = uridine(17) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53368"/>
            <dbReference type="Rhea" id="RHEA-COMP:13541"/>
            <dbReference type="Rhea" id="RHEA-COMP:13542"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="13">
            <dbReference type="Rhea" id="RHEA:53370"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the Dus family. Dus1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.88" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBM3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082">
        <property type="entry name" value="TRNA-DIHYDROURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082:SF5">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(16_17) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="14">
        <location>
            <begin position="98"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1742555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="426" mass="47707" checksum="DE4934A5E21F0AB7" modified="2024-05-29" version="1">MQQSIRQAFMTKLQSKMRLPKGVYLSPMVRGSELAMREVARKHGNASLAYSPMLRDHDVISVHQLIFSKDNEPDQQHRFQSFKELKIDKAGRTDSVEEAAYLLHETSSTDTSNLVVQLCGSSPQSLGEATSAVLDIYHKNSATLPFGIDLNLGCPQECAKREGFGAFLVEKDIDATISCIGSMRQAIDVYCSRITTKPTLSAKIRVLDGGVDDTIAFAKKLKSAGIDFLAVHCRRRQEKHNGEPDWDAGREIVAALPDLPVVLNGGISCFNDVTLVTERTNCHGVMVATGYLSNHQAFNSTIQSETSTEPKSAVELASQYLDFAEIYPPPSYLYIQKHLRWIFRSSLQPENDPSFNATDWKDWRVKMWSFLVRPYLRSVEQFRGFLALYVQQSGNEDRVPDSILRLVSDVTFGSVKKAGKRTAREM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBY7</accession>
    <name>A0AAD8YBY7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006332</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBY7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36974:SF1">
        <property type="entry name" value="DOXX FAMILY MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36974">
        <property type="entry name" value="MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042043685" evidence="2">
        <location>
            <begin position="26"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="287" mass="31456" checksum="A041A82688A69937" modified="2024-05-29" version="1">MMRRRCVPSAVSMLLLLIVSCCVQHHHLLISAFTLPPPSLSRIHQPTTTCSGTVINFDQTTKRGTAKSSSLVIKLLSPSGIDEWPIISQTAVFFGAYAGLALASYPTIKLLESFSQSVVGLERWRIYMIDSTLPILMGLVYLLGGIGHFAAADSFQDIYPPMGTWGIWYLPGSAAFHVAWTGIIELFCGAGLIFSGIRDAIGSEDGGEENILINFIKPICASMLFLLTILVTPANIYMFTHGAVMGDMAPLDMSFHVIRFAVQVTFLSLLFTLARDSFFYAWGDELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YC93</accession>
    <name>A0AAD8YC93_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006248</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YC93"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="333"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="712"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="866"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="909"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="103"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="254"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="300"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="726"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="754"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="866"/>
            <end position="897"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1041" mass="113664" checksum="38BD9EB80063FE38" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCE7</accession>
    <name>A0AAD8YCE7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006203</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCE7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042237429" evidence="2">
        <location>
            <begin position="20"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="286" mass="31671" checksum="39387FDB1643FA20" modified="2024-05-29" version="1">MKCIFLKLTALAMLATASASGVHASSESDEPSSITPQSLRGSFLDENEDADWWGGWQDLTTCTSNCHCHAGSCDQTECRSNCGCQMGGCKGRPKDGRRPTRNPTRRPTGSSSSSFDEGLEAGRREANKLWRDAGNRCSSAWGDFQNTVDRKIRARGWNTGGNRSFNQGARAGMKEVVVEKEKECFRDSADECVDLGNEAARMIAYDHCGSFGMNSVSKKWRRNCRDAAVDQCRGQVFNQVRDECGSPNTSDLRTLQNKCRNKVLTMIGDRSEDYDYSEDSEDLSVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCW4</accession>
    <name>A0AAD8YCW4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dipeptidase</fullName>
            <ecNumber evidence="2">3.4.13.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005758</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C69 family. Secernin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.13.19" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCW4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070004">
        <property type="term" value="F:cysteine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.60.10">
        <property type="entry name" value="Penicillin V Acylase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005322">
        <property type="entry name" value="Peptidase_C69"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12994:SF17">
        <property type="entry name" value="LD30995P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12994">
        <property type="entry name" value="SECERNIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="435" mass="48351" checksum="2E1EF023DD2EB95E" modified="2024-05-29" version="1">MATSLRMLSTSTSIQHHLAIPPPRSCDTFVFVGATSSSGTLFGKNSDRPSDENHEVIRIPSCAHYDKGDYVECTFISIPQAQETLDCILSKPCWMWGCEMGANSFGVVGGNEAVSTLLADELLSPDDGSPTKRLLGMDLLRLSLERGKSSKHALDICIELLEEFGQGGPCCKEDSDWTYENSFLFADAKEAYVLETAGISHWAWERINAGEYRNISNGISIRSNWGALSKDIQSICKENGWWDGNAKFDWKRAVGAGGRAHSNLEACGREASGKIHLEALAAKSKTLQSPPNARWYVEQMALILRDEDSGICFRDLTGFCSTGSQISWLPKSSNVDDHSHFFTAASDPILAKYKRFTFADTIRSEKDDHDSNELWNIWRSIAQQKLRLTGDTLDMLSSIENDALAELDIQRKNTQNKSLSFADTVRKEIDLLQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD64</accession>
    <name>A0AAD8YD64_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_005908</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15454">
        <property type="entry name" value="NISCHARIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="116"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="278"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="413"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1113"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1145"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="36"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="67"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="137"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="343"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1148"/>
            <end position="1160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1743287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1561" mass="174411" checksum="D988F2A2A4D69126" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDL3</accession>
    <name>A0AAD8YDL3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histone acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">QTG54_004775</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetyltransferase family. GCN5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDL3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000123">
        <property type="term" value="C:histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010484">
        <property type="term" value="F:histone H3 acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037800">
        <property type="entry name" value="GCN5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45750">
        <property type="entry name" value="GH11602P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45750:SF3">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="11 16" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7 12" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="15">
        <location>
            <begin position="79"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="14">
        <location>
            <begin position="341"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="26"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1744242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="431" mass="48438" checksum="2218D593295D81BF" modified="2024-05-29" version="1">MSDVEILSSKKRKLSPDAAHEEEGGPSSSSAFHHDSSSPSSSTQHATSSPSPNNTNTTTPNNKLPPRPPNTYDNIRTAIVINDGTRTNLIRLIGLKSLFARQLPKMPKEYIARLVFDRRHKSLAILSSDPEKKDCDDEIIGGICYRAYPEMRFAEIAFCAVSASQQVKGYGTKLMNLLKMHAVTEGIEFFITYADNYAIGYFKKQGFTKAVSMPKGRYQGLIKDYDGGTIMECYVHPTIDFTRVPEMIQAQKQFILERIRAGTAKSDKVVYPPLPPDFYAGQDVKSRAEKGAAERSLAIPGVSEAGWTMADLMASTRDAKDSDKKKHQLKSDLLALVSKVQDQQYSWCFRDPVDTNEVKDYLDVVGDPIDLKTMEKRIRRGDWYKTKHMLFSDMMKMVNNCKLYNGEGNTYYDCAVSLEKYLASISPMFTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFC7</accession>
    <name>A0AAD8YFC7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003418</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFC7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051222">
        <property type="entry name" value="PPR/CCM1_RNA-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47942:SF63">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47942">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT (TPR)-LIKE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="386" mass="43327" checksum="849EDA8B5EF3840A" modified="2024-05-29" version="1">MMERRGSITSAKLAEDLLHLLEEYYFELAPTTAIYNSVLNAWSQAGKMGNDAKVSLYAAVRASALLDQMLDEERQLSGMLPPPNESSFLMVINAMSHAANSALKAGNISDAKNAAINAEELLQKMELQPLETRQIALSCRGSVVRIWASLSGMSGSHDYAARAHTLLMNMAEEAGHLPIDVIYFNVVLDAWARDLSRKDTGQAMSRLSKPRALLMDLIGGKYNAMPDNSSFNHVIRACYAPWASRQNVEEDEDRRNAWEMAFDVYSRMAERHHGACRPDAHTYTHMFKAIACLWPKNTAKSSDERVALCKNIFQSCCQDGQLSKTSFWVISTLLESSELMDLLSHELRDHNIMIKGGLNPDRLYTQMPAEWSRNGRNVKSLNRHKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFD4</accession>
    <name>A0AAD8YFD4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004134</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFD4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042160975" evidence="1">
        <location>
            <begin position="24"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="118" mass="12626" checksum="08A158EE60328531" modified="2024-05-29" version="1">MASKKALAVQLLLLVVLFSSASSFSPTCSPSHRRAAMPHKFQKQFTHIKSDFSLQSSPSNGDQGYNDDAFGLIFLSGGILAKDVDFSGTFLVLSALAATCTTVGTIKFDERIPLLLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YG13</accession>
    <name>A0AAD8YG13_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003507</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YG13"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="132" mass="14881" checksum="6E1ED81427E2E2BF" modified="2024-05-29" version="1">MSYQAVPLGTADGSKAPKPTILTIQVEKLRLISYFGFWGFVAFSVIVSKITVFPYMSCVIDGVDKFGADCTDLKRVFGFNNICINWDYAPSVQLTGMVYPIFEYSFLLYISWTTAKLRTTCSTVFSPLRRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGK8</accession>
    <name>A0AAD8YGK8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGK8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042276515" evidence="1">
        <location>
            <begin position="20"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="107" mass="11617" checksum="D73F0C285AD6ECA6" modified="2024-05-29" version="1">MIRSTLLLVVAAAISGADAFAPVGMATRVNTQLFMDDTGAKKLEDTLKADPQLKESSRATILECDDMECATAQCTQDNRGNWHCEGGLEGERDNVKTQVLMHSDNDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGS9</accession>
    <name>A0AAD8YGS9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_003927</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1746003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGS9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="146" mass="16598" checksum="3B50470BABA547E6" modified="2024-05-29" version="1">MVASNKYTALKEDDNTTSTIMIPTDNTLNPADREIDLRHMDEKEVKSLQKSDPFMYYSIPGVLQASLRHNDVNYSDIASLTHAHPSTSQGEDDTSKVFRRTRFSFECHPSVLMEDLMGELGQELDDDLSLDYDDILSMFGNRSTKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHD6</accession>
    <name>A0AAD8YHD6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Stomatin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_003178</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHD6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08829">
        <property type="entry name" value="SPFH_paraslipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000004">
        <property type="entry name" value="Putative membrane protease family, stomatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050710">
        <property type="entry name" value="Band7/mec-2_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032435">
        <property type="entry name" value="STML2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327">
        <property type="entry name" value="STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327:SF10">
        <property type="entry name" value="STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16200">
        <property type="entry name" value="Band_7_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="4">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1746571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="298" mass="32741" checksum="8E964A35FBB99DDF" modified="2024-05-29" version="1">MVVERFGKLHDIHESGYFFAVPVIDRIAYVIDVRERAVDILPQAAITRDNVSVEVSGNLFVRVADPERAAYGARNPLYAVMMHAQSAMRSAIGELELDEILHNRAGLNTLIKGSLQEAAVAWGLEVRRYELTEITPDDQIRIAMDKQAAAERDRREQVLRAEGDKRRAELTSEGVKISLKNESEGKLIQVTNEAEAEKLKIVREAEGQAEAIRLTALAQAEAIHQIASQLSKDGGQEAAAMALAKEYVKMYGEMGSKSNTMFFQESAGNAQSLVVQAMAAMKAMKLDEVPGVKTPTST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHM5</accession>
    <name>A0AAD8YHM5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Membrane transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_002050</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHM5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051598">
        <property type="entry name" value="TSUP/Inactive_protease-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43701">
        <property type="entry name" value="MEMBRANE TRANSPORTER PROTEIN MJ0441-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43701:SF2">
        <property type="entry name" value="MEMBRANE TRANSPORTER PROTEIN YJNA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="303"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="385"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="204"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1746706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="416" mass="45279" checksum="D5C2525ACFBA42FB" modified="2024-05-29" version="1">MCKVPLLSSSGEPAAATIEKDEKAPLKSASKFTADQQTIIRAGEVWRSHISPAILVFVIVLPMLIYQKEYFSTFFHDTWYVPIMGIIGCTIPSGGAPVAGGVVFLPILTMKNIEAHEAVAFAASTQMVGVGIFAPMGWMSRDPTVLMPSFLKPMFPFALAGLLFSYLVTPLEKEDEVLLVFTIFVICLAIYVIKGLVTSQLDTSQNDSSEEEEAENSSQSTEEVVEDEESAEGYGTMSTTAPVVERQMSKAERRNIVFTPKLFTLYAVCCFLGGMLCGWIGIGVEKVTFFLLTYFHKVDVIAAGLSSITMNGWLSFFAFLLHAVCTPEDEGFGPHLTCGLKDELNPGGHVFGKVPYELWLSVLPGILIGSLIGPAVNAAVGPRNIMIIFVGFLFFDATYNIYNLATNGFIAELFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHW4</accession>
    <name>A0AAD8YHW4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003506</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHW4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="269" mass="30154" checksum="9ECC36AA13C7041D" modified="2024-05-29" version="1">MSQTKASASSAWVKAAIAFMAIVALWNVTKLPFLMSFSNDGNVAYNSRGVELSVNLGHWVKGYRSNKMRTPPCNFMLVHSALGLTILFMMILSLINQTWRKRYCKPFFWFAIIEGIHAIPASLANDAGFKPLFLLACALLVGTGVWGLETNKRYFDNEARAEKHLFIQYTIVTIVNSFAAFLEVPNIISAFKSKTADGTFHSHGDEPHKVFGHTLYDALPEKVGMTIFLGFTIAVWFIWPLLLLDLKKPRQNEENSNGNDTVSEATRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YID2</accession>
    <name>A0AAD8YID2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_003564</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YID2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1745640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="284" mass="31461" checksum="872014E26F59D6EE" modified="2024-05-29" version="1">MTSSPTTLAAVAAGCTLLAYGASRLTKKATSSTDLALTDLDDEIFSEEDCISADDVVAIFDKLFLTMQNVVVQLSQQVQQIQMSGQMIPEAQLRQLLKAEFERALVACQAQVFEENDVDADCLEEATWEFMEEEEKYPKVKRAVERFQKLYESISGEEVVGWTPNKGKTPTAGAKKELSAEELIKAATLYFETLTEKMVEIAKEYKAAGKDLKDPKVSQQYQMEASSDANDVAEEKLKSEMDIVMSDFRAAVDKHSRVPAVGQTLGMLQIKQQQELMAAGVPMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIR9</accession>
    <name>A0AAD8YIR9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002906</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIR9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="121" mass="13092" checksum="8044D200CE0EB655" modified="2024-05-29" version="1">MSSAEEVNSVYENSPIQSKKKHQPVVPKKRMDASVWLKKSQPKARSAKTSGVSSSTIKAYGASTSRSLSSADASFKTKGRGGNNSNNLVGGVHYLLPKTIVPAKASPWPWQFNVRSNNDTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJG7</accession>
    <name>A0AAD8YJG7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Chlorophyll synthase</fullName>
            <ecNumber evidence="9">2.5.1.62</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_001674</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.62" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJG7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046408">
        <property type="term" value="F:chlorophyll synthetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13958">
        <property type="entry name" value="PT_UbiA_chlorophyll"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006372">
        <property type="entry name" value="Chl_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011799">
        <property type="entry name" value="ChlG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050475">
        <property type="entry name" value="Prenyltransferase_related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02056">
        <property type="entry name" value="ChlG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01476">
        <property type="entry name" value="chlor_syn_BchG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005742">
        <property type="entry name" value="PRK07566.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42723">
        <property type="entry name" value="CHLOROPHYLL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42723:SF1">
        <property type="entry name" value="CHLOROPHYLL SYNTHASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0149">Chlorophyll biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041935859" evidence="8">
        <location>
            <begin position="17"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="252"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="281"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="324"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="352"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="384"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="48"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1747711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="408" mass="44198" checksum="28FCB73F1031E212" modified="2024-05-29" version="1">MRSLAVSSLLVASASAFSTAPRSYTGITSTVSQQSSLSMLPTNNNNEDSFYPFPSTESSSNFRLDAKPPTSNDEVTDGSADLRQLLGVKGAAGSEDIWKIRLQLTKPVTWIPLVWGVMCGAAASGNYHWIWNPFDPNDRDVMLGLEDTAKGFVAMILAGPFLTGYTQTINDWYDREIDAINEPYRPIPSGAISEGQVIFQIWFLLLGGLGIAYGLDVWAGHDFPTVLALSIFGSWVSYIYSAPPLKLKQNGWAGNYALGCSYISLPWWCGQAVFGELDRPVYFILPILYSIAGLGIAIVNDFKSVEGDRQMGLNSLPVAFGIDGAKYICAGSVTLTQLGVAAYLYSIGETNYAAGLLALLLPQIYFQATLLLPDPVANDVKYQASSQPFFVFGILATALCLGHHDFTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJJ2</accession>
    <name>A0AAD8YJJ2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-grasp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_001466</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJJ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052032">
        <property type="entry name" value="ATP-dep_AA_Ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43585:SF2">
        <property type="entry name" value="ATP-GRASP ENZYME FSQD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43585">
        <property type="entry name" value="FUMIPYRROLE BIOSYNTHESIS PROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1747503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="407" mass="44316" checksum="154DAFBBA0904974" modified="2024-05-29" version="1">MTNLDNTCSSPTRSEPHHYRNRSLSEAVLVPQATITDDAAAPTVAANGNTNDHYDDVSVDLAEHHEALIGAAFHNQNNIDKQPTLATMGETPFADDGDEVVNHRVIATEVVKEPINFIDAENILQNAIVLLDPRIPDCIHLIEAGRKRGLMVMAVIPKPNDGSKALIEFYPTAQALLEVGMHQVYEPPFGSKFDVVECAANLKTIEAQQNLRFLGVIPCREAAVDFSDILGALLGLSNVNDLGLASARRDKGLMKLAVANAGLRVAKYARLTHGQGKDISSAVEELELKYPVVVKTPRGMGTSDVFICKDEKEAMESSAHIVRGIGPDGRKTQYALLEEFIGGEEFALNLVASPTTPRGVQVTDIWMYHKINTDGTMVNTFQEMVDPQSRAYAELVRYAEGVCRAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YK15</accession>
    <name>A0AAD8YK15_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">JmjC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003158</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YK15"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050910">
        <property type="entry name" value="JMJD6_ArgDemeth/LysHydrox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480">
        <property type="entry name" value="ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480:SF35">
        <property type="entry name" value="TRANSCRIPTION FACTOR JUMONJI, JMJC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="2">
        <location>
            <begin position="207"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="357" mass="40979" checksum="E5DB652BD4235493" modified="2024-05-29" version="1">MSVKRTKKSSPPPSSRSKSSDTAATSSNRISKGTISAIVVILALSYDNFRLRYRASNAESANRNLSSNEDEIKLRYKTWEEAPASYEEFDHDNDPSVCRLPIVTVEEWEKNRMWESETPVIVKNVTDGWKALENWSKEELLRRYPDVVVGMGSSKELGQTGPDQAGSALTRTTIYDYVVNWMHSSNKYVFDRNLRLPDGGFLEDCHPYPMPTRMYEEDPDALFESGMPENLMWKDHLALTIGHDTQGLTFHRHNAAWNTVVFGAKRWILYDAERIANITRLKTMTRDIRNPIQLDTANWIRKLYNKDDRKHEIRNYGHDCVQRAGEMMYVPRGWAHMVLNIGDTVAVVSERGLDGVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKQ2</accession>
    <name>A0AAD8YKQ2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKQ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041932689" evidence="1">
        <location>
            <begin position="24"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="192" mass="22038" checksum="853C274AAD890DCE" modified="2024-05-29" version="1">MKGCWVLLKLDLLFVTRYAVVLSVEFLVNENHEKVNDPAAIRGKVYSATSKGTTAAKAVDDADAHDQLGNMYSKGKGVEKDTNKAVYHWEQAAIRGHPISRYNLAVLDMFNGRFKRATTHWLISACIGHDPSLERLKFGYMRGYVEKDDFAGLFVDTNPLWMQRRVRRGRQQTQPSWMSSQIKDKQLTWRML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLH9</accession>
    <name>A0AAD8YLH9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Metacaspase</fullName>
            <ecNumber evidence="6">3.4.22.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_000522</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C14B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.22.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLH9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12660">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017984">
        <property type="entry name" value="Chromo_dom_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023779">
        <property type="entry name" value="Chromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050452">
        <property type="entry name" value="Metacaspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104:SF30">
        <property type="entry name" value="METACASPASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104">
        <property type="entry name" value="METACASPASE-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00504">
        <property type="entry name" value="CHROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00598">
        <property type="entry name" value="CHROMO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="5">
        <location>
            <begin position="12"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="381"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="381"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="394"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1748583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="410" mass="46570" checksum="6170BC1B4B18978E" modified="2024-05-29" version="1">MMPAKNNDLEEYEVDKVVDHRYRKTAFPDGSHDEYLIKWKGYPSSENTWEPESNLNPSALAEARTLKWTTEQFENTKSDELRKDVLCISACNDWATAADVPNVKISFKLPDAAGKFGGHGGGACCSSLLSILYADEKVPEEDLSFKEIIWKMRKTLIKDPYRQIPQMSSMNPIDVNTKFDLFPDTATGTKRAVMIGVNYVGDEDNELSGAHNDVLNMKRYIQEVRGFEEENIVILMDDGKHTNPTKKNIIHACKKVIRQAEENDAILFLYSVGHGTRVEDDNGDERDGFDEAIVPRDFEENGFILDDDLYEILIKDLPKGVSMFSLFDCCHSATIMDLPYLFKGDEMQAEMTLDPKFNLDAFIEKITGNLKEFVQAKMAAKQKKKAAGSKRKVKPEPSKEKKKKLEQEHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMC7</accession>
    <name>A0AAD8YMC7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMC7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="682"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="692"/>
            <end position="705"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="761" mass="86481" checksum="A8F5D391CEC43E4B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YNC6</accession>
    <name>A0AAD8YNC6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">2Fe-2S ferredoxin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_000384</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YNC6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041995317" description="2Fe-2S ferredoxin-type domain-containing protein" evidence="3">
        <location>
            <begin position="24"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="4">
        <location>
            <begin position="72"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1748445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="139" mass="14322" checksum="D36D61BEEDC0AADA" modified="2024-05-29" version="1">MMKISVRQATVAAALLLSTSADAFVPATTQTTHATTTTSLNIFGGLKGAFSNDDSLGAAKNEGLSNGPRYNENVTVNGKAVPKAVVDQKISQVCASARVKVPYNCQNGDCGTCMVKINGRQAKACVSKVPAGKCAITTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YNF3</accession>
    <name>A0AAD8YNF3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">L-threonine aldolase</fullName>
            <ecNumber evidence="7">4.1.2.48</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_001177</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.48" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YNF3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008732">
        <property type="term" value="F:L-allo-threonine aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006545">
        <property type="term" value="P:glycine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000030">
        <property type="entry name" value="Low-specificity L-threonine aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023603">
        <property type="entry name" value="Low_specificity_L-TA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041359">
        <property type="entry name" value="GntG_guanitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097:SF9">
        <property type="entry name" value="L-THREONINE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097">
        <property type="entry name" value="L-THREONINE ALDOLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017617">
        <property type="entry name" value="Thr_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aromatic amino acid beta-eliminating lyase/threonine aldolase" evidence="6">
        <location>
            <begin position="35"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR017617-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1749238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="383" mass="41621" checksum="866680783DB26153" modified="2024-05-29" version="1">MHMMTPMTVVWRKYRLVGSHVVGRAFSTNNRRIVDLRSDTVTQPTAAMLHAATQATTGDDVMGEDPTVTALEHHAAELFGKERALYVPTGTMANMCAILSHCHYNKSAEMIIGSKSHINLYEGGGYANLAGVSCKQIPEDENAIFSMDDIRDSYFSDNDDHYAKSTLICLENTHNMLGGVALPASYISSIGKMAKERDLKVHIDGARIMNAAVALNTSPSDLCEGADSISICLSKGLGAPMGSILVGETEFIRLARRARKRLGGGMRQVGVIASMGMHALTNNVDRMADDHSRAQRIASELKNAGFFLPRDGQVDTNIVFFALPDNSKLTKEELPAKMFEKYGVKIAGGYSKGGRMFRLVTHMDVDDEGVDATIEGIISLCIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPN2</accession>
    <name>A0AAD8YPN2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Rab GTPase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_001148</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPN2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01867">
        <property type="entry name" value="Rab8_Rab10_Rab13_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000363">
        <property type="entry name" value="Secretion related GTPase srgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050305">
        <property type="entry name" value="Small_GTPase_Rab"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47980">
        <property type="entry name" value="LD44762P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0636">Prenylation</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="176"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1749209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="206" mass="22921" checksum="4CA683ADD3F5515C" modified="2024-05-29" version="1">MSQAAPYDMQCKLLMIGDSGVGKTCLLLRYANDSFSPTFITTIGIDFKIKNVEVDGKRIKLQIWDTAGQERFRTITTSYFRGAQGILLVYDVTDRRSFESIRNWISQIQQHADVHVNKILVGNKCDMLDEKVVSTEEGQRLAKEFGVDFFECSAKNDINVEQSFLGLARAVKDRLVQDGGGGPSTSGTRSLKNPPVSGNRRANNCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D518</accession>
    <name>A0AAD9D518_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_015976</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000051">
        <property type="protein sequence ID" value="KAK1733259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45911">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="745"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="895"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="6">
        <location>
            <begin position="251"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="6">
        <location>
            <begin position="469"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="817"/>
            <end position="848"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1733259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1725" mass="192506" checksum="9B0D98B0500FFD6A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D522</accession>
    <name>A0AAD9D522_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000052">
        <property type="protein sequence ID" value="KAK1733228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D522"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="172"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="438" mass="50285" checksum="BC77CAC2D4BC7DA1" modified="2024-05-29" version="1">MVAKRIPTGYQLDINWILVDTGWIPATTSGDQRRPTWQPSGDQNKAGWILNGDHRSVDQEKITTISRLLYLQRLDTHLRDENGDCSSSDSDADDSSADESSEEEFVEDAYDLSEFLGTTILRERMSDSRRGRTRREEESRAAAVDNMSAPIAGSRSGRTQHVAEADGERTTSNSQNQSSSNSSPPKNWLYLYDTYPVLSGRWKYCEEYIGAKVIDYGKKMAMRLDPSSKWFDWKTHSCGLKYEFALAIYEARVVSVRGPDYPSTHDITVFRGGTTDEDINDRDQNALYFQLEEGHKCVADSGYAGEPEKIVMTQDEHPKDFEEFLARCKNRQETFHWRLKAFNILGGRFRHGISVEHRMELHRMAVDVIVGVIQYDYENGHPPFDRLREVETKWRPSGDQVDIKWIPLDIKWIPLDTTGYQRIPNGYQLDTKWIPNGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D582</accession>
    <name>A0AAD9D582_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_015854</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000049">
        <property type="protein sequence ID" value="KAK1733439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D582"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042253091" evidence="3">
        <location>
            <begin position="25"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="208"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="300"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="420"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="365"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="208"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="236"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="422"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1733439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="500" mass="53161" checksum="A9E01C4992DC6A89" modified="2024-05-29" version="1">MMKSIYTTVAAVLIASLLTAEAWSTSSPTSVVNRINQNHVIVAPHDVNAAHLTRSTTKLSATAANKNTSLSRSALVSKLANNLHLNLIRSLIAKLTTFLTHKSKLVILSTMLTIATFFPQSAVAAKSSLFSLGGGGSTKDSAVISTGSNNDGGGGVMKVGKFVVTVGAIGAGASTANKVMRNKFTCNDDDDESAGGDTDGSVMNKTVVSKNEESPNGTTNGSVVQSSSAQKQPSAENKKTEEANNKTEEIEPLSEEWIQQQLNDAEKRSNVLNDAIKMTQQSSAPVAPVVSTKSVAKVTTKSPTKVNGNKNSSSSKKKVSVGNTIGIPPTKTTTTTTTPLVKNLDSKIEMLQRRDAERSIQQQRINDEQAQVEIEKKKVALVEAERKIELAEMEYKKSQQQQQQEVKQVVEEKKEEAVIINSAPITTTTPQSTTTTSPPPVPAQPSPAQATTPPIKVGPGGSPAKSKEEDLELTTQVILEYVKTMDSKSSGVVDDDSDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5H0</accession>
    <name>A0AAD9D5H0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cobalamin binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000038">
        <property type="protein sequence ID" value="KAK1734547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5H0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1980">
        <property type="entry name" value="Nitrogenase molybdenum iron protein domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051030">
        <property type="entry name" value="Vitamin_B12-ABC_binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42860">
        <property type="entry name" value="VITAMIN B12-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42860:SF1">
        <property type="entry name" value="VITAMIN B12-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53807">
        <property type="entry name" value="Helical backbone' metal receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="1">
        <location>
            <begin position="20"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="484" mass="52220" checksum="65335E73F0625228" modified="2024-05-29" version="1">MTSKQEAASNDDDQTTTPPRVLSLLSAATEIVCRLGCSHLLVGRSHGCDDPPLITSLPVATAPRVDPNAPSAALDAQVRVQSASGGPIYQINNHLVTSANPTVIITQEQCRICAVTPDDLNQACQNLPPTAKLITIMPVSLDDVLGDVITISNALGVHERGERLVKHIKRQLADLNTTALSVLGNNPKPKVAHVEWLAPLMGSGYWIAECVAFAGGEMVHGYPGGHSQTLEKIGLLSNADYIILGPCGFSIERTNEELNAIKLLDSEEWQSLPAVKNGRVAIADGNKYFNRSSVASMLGSAEIVAEFIYSELRGMYGHHGTRWVRLEELSAFCSRTGAEAARKEVVLAEGVVESPNNVVQQNGLKQESSPEHSETVKHVSNQIAALTRSDYASAFAMNSAANQKHLVSAEKFEAIVSVWPSFRVLTLSSTSCQYFEGTSDGSTTSSVKVDAMPDDSDEVLHFVFDIRKSEDGKRWETDGVRIDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5T2</accession>
    <name>A0AAD9D5T2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014866</name>
        <name evidence="1" type="ORF">QTG54_015312</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1734054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5T2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="146" mass="16272" checksum="60FEE80194CEDC88" modified="2024-05-29" version="1">MSSTRTVSVRFADTAQLHIVNRQQDFDKKNGVARNELWYTAADFHSMRRAFAQDVFHVRARALAGVPFNYAGDDESSVCIVGMENFLTPGLMLEMSACRERCTDAVLAEQARDDPSARAIAIASFAQSKKVVRRARMIGKVLQDSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8X2</accession>
    <name>A0AAD9D8X2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8X2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1738432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="405" mass="46102" checksum="24AF8B3A2EBA9756" modified="2024-05-29" version="1" fragment="single">MDDDGATTSSHRLCFQCGGLGHKTCYCTSSERNNNDEDKESYKRYKDNRKKNHTHFDKVVNWMADNNPQEEHIAIDPLVWLNSQAPTSIDGSCVTQRCLDMHRSKYNDLDKAQRTVFGGTIAQLKARLADRLNVSPEDEGTSQWHKQLTRAVELGQPAEFSANNEDEQCIKVYAVEKLQPRCRQLHHLIFHDNSFCAKIRSKLLPSATNSLTTHCMSLGGGPGFDHVSFCIATKFLHDIQPKRSHLLPNRIKTQVYDLYNDDWEPVMESLGECFDDQEHLTMHHVDLRLDLADEAHEQLRSSLQTVDIIIAQFVLHENASFIAQDVEIDGVPQKQIVGVMRDILTMAPAGTIMIITDSANTLFPYLKDAANKNGWTYLCAEEQLREEGKRRAYLGPKSFLILERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8Z8</accession>
    <name>A0AAD9D8Z8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Calcium/calmodulin-dependent protein kinase</fullName>
            <ecNumber evidence="11">2.7.11.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_010537</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.17" evidence="11"/>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8Z8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004683">
        <property type="term" value="F:calcium/calmodulin-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13469">
        <property type="entry name" value="Sulfotransfer_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 7" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="29"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="10">
        <location>
            <begin position="727"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="915"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="963"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="924"/>
            <end position="934"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1738507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1171" mass="131615" checksum="AA824D340F5ED3EA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9P9</accession>
    <name>A0AAD9D9P9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_011338</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9P9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16448">
        <property type="entry name" value="RING-H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051826">
        <property type="entry name" value="E3_ubiquitin-ligase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765:SF434">
        <property type="entry name" value="GB|AAD18119.1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765">
        <property type="entry name" value="RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="234"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="105"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="120"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1738044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="317" mass="35901" checksum="485E33C95A7ECC4C" modified="2024-05-29" version="1">MSSYEPDITMLFMLGGGVLFVWGFVRSVYLCFRKLLYGEERGRTSDDEPGEIYRIMSSARQEEIVDLRKNAILRYLSRFTLTLGDEHLLCCTGSHTDTAFSLSENEEVNDGSVTANETCKGTEKNDDIEKGNKDDVQDIGIGDMAQDSTTAADKYTHISIPLPGCDIEGIHICSCSMEAEKEDRQEGNKWKLPSLFQTRDDDAREKQGPITITSDPNHHQQQQKVDKRSVPIFCAICLSEYETCDRVCWSSNTDCSHVFHEDCILQWLISSGKKRSMNQSFTRHPTDEKLLENEFCPCCRQDFICVRPALLGSEESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAM1</accession>
    <name>A0AAD9DAM1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010365</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAM1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052394">
        <property type="entry name" value="LRR-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114">
        <property type="entry name" value="LEUCINE RICH REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="56"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="580" mass="65203" checksum="8B4C34A3811BC0A4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBH2</accession>
    <name>A0AAD9DBH2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009633</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBH2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1739874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="230" mass="26114" checksum="2314FFDDE61F2FBF" modified="2024-05-29" version="1">MLAFFFCIDLEEIQLNDGLKIIQEQAFSQCTFLKRIHIPSSLITMGKKAFSGCASVTEVTFPAGPGRIGIGYGAFSSCTSLERVVTPLNIHLMSTNHQIFSGCTKLATVELIGDVRELVSSLCVKQHKRTQLALEILRINRVIPKLTEDRKITKLHEWMESINYKIECYKLEHNKMMKEALTSIELGLWKIKLDDEHVTTRNKRKRGQCRVNCGADVVIKNVLPFLTLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBL5</accession>
    <name>A0AAD9DBL5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_007820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBL5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057491">
        <property type="entry name" value="DiatomPyrShell"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25192">
        <property type="entry name" value="DiatomPyrShell"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1741342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="106" mass="11538" checksum="0ACD4523629794E9" modified="2024-05-29" version="1" fragment="single">GALRTYPFNPTVDSVAIILKTDGRPLNARIELLQGPNNNKQVVELYTEDGLDRPFFAIVETPGSGNVVRVVNTAPVEFPLYASVDAYRVGGGMDWPDDGLMIGRAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBL8</accession>
    <name>A0AAD9DBL8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008014</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBL8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="38"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="215"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="296" mass="33041" checksum="FEFCE48E739BC2BD" modified="2024-05-29" version="1">MQSFNSIDAERELLVYIPDESIAILTEDLNNQYNIMRRSSPQKLPTDSRLDIEQGSGNSAKKRINPVRNLDPEECIDPEESNNNRPTITTAYYSSPFSPSPPTNHNNTNQSPLQKFVTQLLPTILKDTLLGVSLGVLFLLTLFFLDYKNFISTGSTKAFQTAGVQLLSDPEVITTIESSLDVKLVPLDSYTAMTAEIKSNRDLLTSKDSGATDLFTKYTTQLSQVQVEIDSLKEEHDAISTEITTKFGLEMDKWCGECKGGWGKCDARVEYLRSTYGNNVILSKVDIMKEGLCLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBW0</accession>
    <name>A0AAD9DBW0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA repair protein RAD51 homolog 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_007230</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBW0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033063">
        <property type="term" value="C:Rad51B-Rad51C-Rad51D-XRCC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033065">
        <property type="term" value="C:Rad51C-XRCC3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005657">
        <property type="term" value="C:replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000400">
        <property type="term" value="F:four-way junction DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000707">
        <property type="term" value="P:meiotic DNA recombinase assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052093">
        <property type="entry name" value="HR_Repair_Mediator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46239:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46239">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 3 RAD51C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecA family profile 1" evidence="8">
        <location>
            <begin position="148"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1741657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="419" mass="44784" checksum="D1FD5313012B1975" modified="2024-05-29" version="1">MTTVAEAINITQTQQKLLSIPLLSLPLRPSTLTALLRRGFATTGDIMINNTNTMKTGNDDGGIENLAEELGCSVSQSADYVHEINDALYSIGLPPLTANTTIVGRTDGTTKNNNPTLRSTNNIPATAASLLRSKLNSHMQQNSNSSSTARQIVSFSQPLDMLLGGGFALSELTEIAGLPGSGKTQLAMQLCVDARLPGKYGGVEGCAVVIDAEGSWSGAGVDRLWSLAGALVDHVKSSALRKMEANKAKEMANGGGANTDTTAPEELVPTWFTPESILDGIHIFRVHDESEQTCTLYNLPQFLQDQEEKGKPVKILVIDSLAFHYRVASSINSSNKGNFLSTTTSLTRMAAFLQELASEFDLAVLALNHLTNKLDKDSTGAGGMKLVPALGESWAHSVTSRLPNPNPNPNFAMMFAMYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBY8</accession>
    <name>A0AAD9DBY8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Membrane-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBY8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042242606" description="Membrane-associated protein" evidence="1">
        <location>
            <begin position="28"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="504" mass="55765" checksum="A84F7D4DD9A54F46" modified="2024-05-29" version="1">MMMSRRRLFFCGCCTVIVLLIQVSVQATNPSPQSLQTTNQPFHGHVISNFLNHRCGSSFKDSSRPSVWTYGGTLSDPLTGKVIAEVEGLEVMKQLPTITSSKSSDKALLNNLCTKHVLFPKQKTQSSQPSWDTATTILSRKLFCYRRPSNMNNASGKVDSESPSKSLLTSLRLRPDGPLRHLSPLENMAVYDSAITYITRNNGREMVVLTELGGGKADDIDGINNSVYDDVDDGKKHYVMGSAQCERDASSFSFAIQALKGTFNSDGDHGPMLPPLKHPSSDNEVVISPPRSRLLQFGKGDGSSAGGSAASERKYRTVRESYSYSLQDGSDTSDISEKEQIVDTSRFDLIRRLRKQKQQPNLMVEEIQTPCTVKYTRYGEAPPWYAPGRMCNLELHGRRLADDKSTSQDLSPLLSWAASKCKPSFWSGWPTISQTSTSDSKEQALAQQAVRLFSNDSRRFIVPDDDSTDTEGASWVSAAENTLSRVQSRLKRLSKSFIVSEVPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCB0</accession>
    <name>A0AAD9DCB0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Histidine phosphatase family protein</fullName>
            <ecNumber evidence="5">3.1.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_006866</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCB0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050645">
        <property type="entry name" value="Histidine_acid_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567:SF110">
        <property type="entry name" value="2-PHOSPHOXYLOSE PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567">
        <property type="entry name" value="ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00616">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00778">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042168962" evidence="4">
        <location>
            <begin position="33"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="591"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1742301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="672" mass="74674" checksum="2AFEDFA73D67012C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCS2</accession>
    <name>A0AAD9DCS2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TraB domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_006259</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCS2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14726">
        <property type="entry name" value="TraB_PrgY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002816">
        <property type="entry name" value="TraB/PrgY/GumN_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046345">
        <property type="entry name" value="TraB_PrgY-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21530">
        <property type="entry name" value="PHEROMONE SHUTDOWN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21530:SF7">
        <property type="entry name" value="TRAB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01963">
        <property type="entry name" value="TraB_PrgY_gumN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1742662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="324" mass="35781" checksum="370D20C8FD708542" modified="2024-05-29" version="1" fragment="single">IAARTYASTTTISSSSSDTKAAAICDPTIESYQKGSNKIHIIGTAHVSSVSAQLAGAAVKEIKPAAVFIELDPQRINRAFRNGRITQAVNIVFFAESKGQVTMRMAKLYPQDFEKKSKGLFQVLEKMRIQNPIQEMYEGLEAQGITPGEEFVTAVEEGLQNNSIIILGDRPMDITLKRIAKALFFDTDLKKLAEADEIITNKMKDRVPELQEWERQMNESGQQTKELSPEEFSIFVERLKTKETTMALMNEVKKAAPALYEALVGERDVFMGRAMDSTASALLPSLIPSGLRTMVSVVGLGHVEGIGRELISMGWSKFTPANCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DD47</accession>
    <name>A0AAD9DD47_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Eukaryotic translation initiation factor 2 alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_007838</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DD47"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005850">
        <property type="term" value="C:eukaryotic translation initiation factor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04452">
        <property type="entry name" value="S1_IF2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000795">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.190">
        <property type="entry name" value="Translation initiation factor 2, subunit 1, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044126">
        <property type="entry name" value="S1_IF2_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024054">
        <property type="entry name" value="TIF2_asu_middle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011488">
        <property type="entry name" value="TIF_2_asu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10602">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10602:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07541">
        <property type="entry name" value="EIF_2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116742">
        <property type="entry name" value="eIF2alpha middle domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042209536" evidence="4">
        <location>
            <begin position="31"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="91"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1741360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="305" mass="34978" checksum="0C09EF08706E1252" modified="2024-05-29" version="1" fragment="single">ETHVSSTLFQLISSSVFSLIAVICKGPVRGIINNATILTTTNKQTIMPEVATDAVPTTLDEPEEGAFRLYLAEDKKNLDCRFYEAKYPEIESLVMVNVRTIADMGAYVSLLEYNNIEGLILLSELSRRRIRSINKLIRVGRNEVAMVLRVDKDKGYIDLSKRRVSPEDVAACEDKFNKAKAVHGVLRHLAERRKFHLTELYERIAWPLYRKYGHAYDAFKIALAEETGGGVVIVRRRIHLRRWRSLRILLRNSSCIFEGGWHLNLSKYVRMSRYRALPMMGLMPFVRHSLRGLPLVRIIHPSKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DE84</accession>
    <name>A0AAD9DE84_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA mismatch repair protein MutS family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_007033</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DE84"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051026">
        <property type="term" value="P:chiasma assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF20">
        <property type="entry name" value="MUTS PROTEIN HOMOLOG 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair protein MutS core" evidence="6">
        <location>
            <begin position="358"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="7">
        <location>
            <begin position="728"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="230"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="235"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1742468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="962" mass="106529" checksum="6E48242E4B654118" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DF04</accession>
    <name>A0AAD9DF04_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA methyltransferase 1-associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004098</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DF04"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027109">
        <property type="entry name" value="Swc4/Dmap1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12855:SF10">
        <property type="entry name" value="DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12855">
        <property type="entry name" value="DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="405" mass="46061" checksum="6ECB61991CBDA852" modified="2024-05-29" version="1">MAFAFQERYSEQSSKGGRFAISILSGWKYIGTEACSCGSDETFWCIHTRWSRRGVTFKRYGADATVAEASNSQPAASTYNHPSIHPRVRHLSLHSSSHQLHPPSPSQTLVYQIVARCSTGRRESKTQAIRVHLEPISGRSTRRGSIACRTESSRSAVEKTEKGWKAFGPIRISIGSTAATHKEGKYCINQGKRCTNQGKRGISITAAPASARPTTTVVSAAPVDPFFRAHQEVDASFNETAPVPTPGTPYLQSGRLFPPNIEGHAKLKKSTLKQMDEILSELGVPKEPIPTKRSCDLFDGVRKDAMTLLILQKMALRKRLNWQRRKPSWRGGLREPQPQPPRRRRGKTKVQKRLPQKAPNQLKRRKNRLRMQLLELLRIKQHRKRRERIRHLPPTQQQWWYHHQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DF44</accession>
    <name>A0AAD9DF44_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005446</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DF44"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11378">
        <property type="entry name" value="DUF296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.80">
        <property type="entry name" value="Hypothetical protein, similar to alpha- acetolactate decarboxylase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005175">
        <property type="entry name" value="PPC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34988:SF1">
        <property type="entry name" value="DNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34988">
        <property type="entry name" value="PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03479">
        <property type="entry name" value="PCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117856">
        <property type="entry name" value="AF0104/ALDC/Ptd012-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51742">
        <property type="entry name" value="PPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPC" evidence="1">
        <location>
            <begin position="11"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="189" mass="20191" checksum="9BEAC4F0EC85FCAA" modified="2024-05-29" version="1">MPEPRLIVPPCGAMTAHAFRLHPGEKLMPALKQAAEIILARSKCESAFIVTAVGSLERATIRLANASRTDGDDTGGNDIKTHNQRFEIVSLVGTFSADGSGCHVHISLSDAEGNTIGGHLMDGTIFTTCEIVMGTAEDVKFTRIMDDSTGYNELEVIQLPKQQSDAWKAIPAALMILAAGFIAGRLKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2024-10-02" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG22</accession>
    <name>A0AAD9DG22_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002988</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1299" mass="143723" checksum="E86E0016540E49A0" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGI0</accession>
    <name>A0AAD9DGI0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGI0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="248" mass="27628" checksum="9475DFE0BA447C88" modified="2024-05-29" version="1">MSQVYSTEPATTGHVVFETTHGPIDVNLWCKDVNKIEQYVGDALRWDRKKLEVNPRIRFNHRGQVAMALPLEESTNNTDTEETAMLLAGSTMFNALRIGRTDADDQTGIPTDLEDAPPRIKSVKIDYHPFEDMVITAEKKLPFRKTAANGDGGMGKGGANGQQSTIEKRRKKRKQVRNLNILSFGDEERDYDAITSSAKVSTSMKSSHDFLSAKVDADVEKRSKDKEGEGNKMKSKQKSAKASSLRHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGR3</accession>
    <name>A0AAD9DGR3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LAMTOR3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGR3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071986">
        <property type="term" value="C:Ragulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071230">
        <property type="term" value="P:cellular response to amino acid stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032008">
        <property type="term" value="P:positive regulation of TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015019">
        <property type="entry name" value="LAMTOR3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13378:SF1">
        <property type="entry name" value="RAGULATOR COMPLEX PROTEIN LAMTOR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13378">
        <property type="entry name" value="REGULATOR COMPLEX PROTEIN LAMTOR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="71"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="13"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="212" mass="22440" checksum="49BBC77778D9538E" modified="2024-05-29" version="1" fragment="single">LVGTNEGVGLSRSLGSAHTASQLRSNNISHSGSMSEEVLSSIETVWATLVSAAPPHVMAATAAAAAAAANSAANGGGGSMEEEKKEDSAPTHIQPPHPLLSPLQLGDTIKTVTATYDNCTLIHITCLRWWYIRGITRSKYRCYPMHGVAITKSIIGTSETCLGTKSWRWCNWGEYCHGKYWEWYDDGTDDGCGGSDAAASTTTSAATATNDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJ72</accession>
    <name>A0AAD9DJ72_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001156</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJ72"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1749217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="200" mass="22796" checksum="051735E2BB35536D" modified="2024-05-29" version="1">MSSIYADSSSVYWKNRQKRHNRLITCIAIAVLALVACFGVVHTTNKSKILSQRRSLEETNERHWIECEARVDSRKECTDICQSERNSIQRKTMHQSCIHGCQQSHVASTALGCRGKTDGKGRHRKHVTEEDVFQDVGVLAHEHCYKFQSVDPKPDVFATCRKYHRAGTKQGYRSGMAAMATVLEEEWESIKAERLANLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJ99</accession>
    <name>A0AAD9DJ99_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MORN repeat-containing protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000138</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJ99"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23084:SF263">
        <property type="entry name" value="MORN REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23084">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="319" mass="35237" checksum="3EAD744D22827AE4" modified="2024-05-29" version="1">MTTKEIQMANTSAVTRVSDNLGSKSKTSAQAQASSRSRSTASKLVHGNDIDIEGGASISRASDSWMNERRGVKYVGVFVMRNGKPEGEGAITYGKGRGGVYTGHFKDGKPHGFGKMDWERGDSYEGMWQNGKKHGTGKCTYVHGHAYEGEWREGKKHGQGKMDWEGGDSYEGMWQNGKEHGTGKCTYVHGHVYQGEWMEGKKHGQGKMDWEGGNSYEGEWVHGKQHGVGKETRKHHVYEGEWVHGKKQGVGEMKYWSRADGDVVKGIWKNGNLRAGKVIYANGDEYVGDLRSGFPDGHGKMTKANGTEFEGDWCLGDAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJP8</accession>
    <name>A0AAD9DJP8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJP8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="319"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="441" mass="47879" checksum="8A6882D20AB6EC91" modified="2024-05-29" version="1">MFDPSASATSRLAEIHSRIVKNGADHSLPPRSETYHLRQEPKLLDVTITILSLTGFRAKENKNRISISADGNRDMTNAACKMVASFENGAKAETSHGTPMTHIPSLSFQLPSPFSHSSTFSDIVSWPEQAAACFWPEQANEFANMSSYQFQRKFVPEGGTGRLQPQVCPIQISVSRNGNMYKLGVASVLVNGEEGGESSTIIPITIDERVFSGAKQQLDELKMPMVTLKGDTMKCSLERNSSIRVLVKVSDPKSTDFTKPVSHFIEDPALSAVSNESDEGQGKVEEEKEAVQYDMDAFSGATLSRAHSNESSIRSAPTDSSSDFSSALDSHPYSTDDEYDDWSIYSASSSGLAKLKDQLRNGGWLRSPASLDDSASASLDDTTISSSSSITTASVMSEMVSSIRNSFPDSKSKAKSWVNRFACGVQLCGCKDKEGDLLQLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJW1</accession>
    <name>A0AAD9DJW1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJW1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="237" mass="26197" checksum="58A8A926AC3864AA" modified="2024-05-29" version="1">MLFDRPILRTASDAIAVDAFELDNGTSSDERQSTQQQQQQHQHHSITYKHSFTKVVLAIYYINLFLVLSNYTLVMSHSVKAMAGDNICLPTAGIFASLLMFGLSQVRTMANLGRSISVVSLAALFIVVVQCLYALRGSYYSEDDEEAAEAQEEVYSTDFQRTLAKMSAVASIGFAVGSQKLLLNIRHEMKDRKQAAPGSLSISLSLFGLAYVTVCLLADLTLHHSYLTQFQLGCHDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XS10</accession>
    <name>A0AAD8XS10_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016959</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000071">
        <property type="protein sequence ID" value="KAK1732355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XS10"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00121">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045005">
        <property type="entry name" value="BPM1-6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002083">
        <property type="entry name" value="MATH/TRAF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR26379">
        <property type="entry name" value="BTB/POZ AND MATH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR26379:SF187">
        <property type="entry name" value="OS07G0655300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="130"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="250" mass="27062" checksum="44B0F9E12A2EFCF9" modified="2024-05-29" version="1">MDPGCLPGGLGVSANGYVSIYLGLCAEVNIAVTFAVALLDKFGHTKRVSRVNHRFDGTGDVKKLPSSGWNDFIAHSDILDASKNILGDDDELTLVVSIEIEQPATVFDPIDAEHTLVKMIQGMFRDEETADVLFEVSKMEANEDGSKRGKSYIHFPAHRSILQGCAPMLAALFGTSNKGELATVAVHDVKPKVFRLLLWYVYGGTVSNEALKADAKDIVDAADKYSIVDLKLAAEAALVESTNITVEFED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSF8</accession>
    <name>A0AAD8XSF8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_016696</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000062">
        <property type="protein sequence ID" value="KAK1732635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSF8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1732635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="271" mass="31298" checksum="D552C71F8158E71F" modified="2024-05-29" version="1">MNHAGVTNHDSVVFVYTGGRVPEHLRERITHAIIDKSVSVIDEYAFQDCPKLQSVACHKGVEIIRKCAFMSCNGLRVLNLPGVKHIETWAFKKCRRLFQVIFGEKLERIERMSFTGCRMLRHITIPLNEGMAIGGSLYLNIESVWLVEGIRKLIASLHFERWTRRMEMEMNEIHRTVPCARGKSKTSVIKEWMSSMIHLLKHFKAEHCIVVNEAMTLLELALWKAKLDESHKEPKRKRAKIDSGIIRKERRVTCGADIIIKNVLPFLQLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSI9</accession>
    <name>A0AAD8XSI9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ankyrin repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016455</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSI9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052420">
        <property type="entry name" value="Espin/Espin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153">
        <property type="entry name" value="ESPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153:SF8">
        <property type="entry name" value="FORKED, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="241" mass="26405" checksum="A3A65F527DD76490" modified="2024-05-29" version="1">MCKLHNFPSSTNTYNTMANKSAASSLMLLLQLIQNQDWPKMNNIFLQPEKFRSLSALINQSSSFNGMTLLHAVCRFNPPSSVVRNMIMLCPEDAEAIDCLERTPLHVATGTGASVNVINALLEANPSACRAQDADGRTPLHMACDRNCVLFEGSVNSNDAPRYDVVNSLLSVSPSSVTLEDADEMTAIEYALLSSGDLRVVKMLQRASQKVLRKKHAEEKSNKQQLAGFAPKDKVFTARSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSN8</accession>
    <name>A0AAD8XSN8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Subtilisin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016514</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000057">
        <property type="protein sequence ID" value="KAK1732802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSN8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042195187" description="Subtilisin" evidence="1">
        <location>
            <begin position="20"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="276" mass="29860" checksum="E54ACE22FBC14A40" modified="2024-05-29" version="1">MHIYHFVLAILSFSCTAAAGKTLNLRKVAANDPTMSDVPSSSSVIAPNHQQAIDKPQCALEVASLNRGDVQIELPGGKVGFEKFPNCTTIFSLKFLADIGVDHSTCIMSVPQLTKASFHMSRFREYMPKEALDYLEYLKGPITTGRAGMVTCEVPSGQFSKMHAVKAWRPYTMTEGWHYLTYTDCNDDGWVGSGQGGTVDVDIKYKGKLGHASPSHSSRGGHELISMVSTSYHVGNVGDEATNACCSPEPGVARDCSAVHAMIDNFDLSSVDKDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSX1</accession>
    <name>A0AAD8XSX1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016426</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSX1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000202">
        <property type="entry name" value="Small ubiquitin-related modifier I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022617">
        <property type="entry name" value="Rad60/SUMO-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10562">
        <property type="entry name" value="SMALL UBIQUITIN-RELATED MODIFIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11976">
        <property type="entry name" value="Rad60-SLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="23"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="100" mass="10996" checksum="F7B3AF59C45F9457" modified="2024-05-29" version="1">MSDNEGQKPADGGEDQKPGAEPITIRVRDQTGEETFFKIKKSTKMSKVIQTYASRKGVDSTTLRFLVDGERVQPDDTPGSLDLDDQDQIDCMLEQSGGCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUH3</accession>
    <name>A0AAD8XUH3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015587</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000045">
        <property type="protein sequence ID" value="KAK1733732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUH3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36489:SF2">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36489">
        <property type="entry name" value="PROTEIN-COUPLED RECEPTOR GPR1, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="367" mass="40632" checksum="C44AD211CB4B5F26" modified="2024-05-29" version="1" fragment="single">HKSLGIKKSSRYASNIITHEYSIHHLIQSSSRMRVIFLALLGMSVIIKVAAGEELETQCTGDNKLHCCKQIQNGESTAEEVCASFDCSLDIECDDSDGDSWDEYYREERDLGYKPSGGWNSKQSNSWSDWSGWNSKPSGWNSKPSGWSKPSGGWDSWSKPTKKPTWAPHSDYPTVLITEPPTRNPTRDPTPNPTNPPTNPPTPVPTNPPTNPPTPVPTNPPTPVPTNPPTPEPSPHPTPHPTQKPSKHPTKEPTWMPSEKPVWSPPVWKAPAPAWDGWNKPTKRPVNAWNGWSKPTRRPVNAWNGWSKPAWNSWGGGWGPKPTNKPTQPPVNAWDSSWSGKSPTDWVLNGWGGDAWTNNNAWGGDGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUK8</accession>
    <name>A0AAD8XUK8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015679</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000046">
        <property type="protein sequence ID" value="KAK1733636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUK8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21113">
        <property type="entry name" value="AGAP001705-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21113:SF4">
        <property type="entry name" value="CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041961614" evidence="2">
        <location>
            <begin position="33"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="483"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="594"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="944"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1070"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="494"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="514"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="600"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="960"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1080"/>
            <end position="1090"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1221" mass="132018" checksum="893BBD8CCF2BE6CC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUP0</accession>
    <name>A0AAD8XUP0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Histidine phosphatase family protein</fullName>
            <ecNumber evidence="1">3.1.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015536</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000045">
        <property type="protein sequence ID" value="KAK1733681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUP0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051710">
        <property type="entry name" value="Phosphatase_SH3-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16469">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16469:SF27">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="221" mass="24446" checksum="7AE41E4BF2893256" modified="2024-05-29" version="1">MDIVAEDVVYLTRHGARIDSDDSEWLKKCNHNRSDDPHLSPSGHIAAKELAKRLRKTLPDNHIKHIISSPYIRCVETANAIAKELHIQIKIEPGVAEVNSCRNPQFLDAEQLQIQFPSIDSTYTPVMTREGLPLEYSDGACANRSATAARKVRRKLTGAILFVGHGASCYGVAGEFGHRGYVGYTSLTKFSQHDGGKYRLIGSFGDVSHLTDQRTALDSAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWL5</accession>
    <name>A0AAD8XWL5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Photosystem II stability/assembly factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_014297</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWL5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028203">
        <property type="entry name" value="PSII_CF48-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47199">
        <property type="entry name" value="PHOTOSYSTEM II STABILITY/ASSEMBLY FACTOR HCF136, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47199:SF2">
        <property type="entry name" value="PHOTOSYSTEM II STABILITY_ASSEMBLY FACTOR HCF136, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14870">
        <property type="entry name" value="PSII_BNR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110296">
        <property type="entry name" value="Oligoxyloglucan reducing end-specific cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="2" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042121935" evidence="3">
        <location>
            <begin position="35"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="Photosynthesis system II assembly factor Ycf48/Hcf136-like" evidence="4">
        <location>
            <begin position="88"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1735231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="277" mass="29461" checksum="941A29B521163286" modified="2024-05-29" version="1">MVLHHPPIDHNTKTITMKLFSAAALVLAASNVSAFAPSTGMRTANSALSMSTSNSEEDRRSFVTKSATGVAATALATSTTFGAPLVVNAAASKQWRQIKVPFEDTVYDIDFDSPTHGYIVGARGSFAETNDGGLTWEPRSFSNLDAEEEITYRFQTVSFENGEGWVLGKPTLLLHTKDGGKSWERIPLSPKLPGEPTGILATGPNSAEMITSSGAVYTTENAGRNWKAQVKETIDATLNRVSSSGVSGASYFTGSIANEQRDSKGLTSLCRVVVTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWQ3</accession>
    <name>A0AAD8XWQ3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF285 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014589</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWQ3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005046">
        <property type="entry name" value="DUF285"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011889">
        <property type="entry name" value="Liste_lipo_26"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02167">
        <property type="entry name" value="Liste_lipo_26"/>
        <property type="match status" value="21"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03382">
        <property type="entry name" value="DUF285"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="956" mass="105970" checksum="B03FF20D724BBB40" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XY72</accession>
    <name>A0AAD8XY72_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">OsmC-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_013781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XY72"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052924">
        <property type="entry name" value="OsmC/Ohr_hydroprdx_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35368">
        <property type="entry name" value="HYDROPEROXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35368:SF1">
        <property type="entry name" value="HYDROPEROXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="OsmC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1735618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="220" mass="24110" checksum="031B7B917B67A285" modified="2024-05-29" version="1">MQMIKLITGASFVRAGVAFSVRRSPYNSPSILGAKYETVLLTRCFATVGSKEIIEEDDEMHRKHYAITGVGQRSKVTCNTNTNHTLEADVPKKMGGGDEAPQPVEHLLAALVGCTQATAVYVGRMMKPRLIIEKIDFNIDAYRDERGALSLPITELPTIPARLQSVSGSVAVHFQNGVEVSEEQLRILGQQTEARCPVANMMHSSGCIMDIQWKNGADIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYY7</accession>
    <name>A0AAD8XYY7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pentatricopeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_013562</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPR family. P subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYY7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050872">
        <property type="entry name" value="PPR_P_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46128">
        <property type="entry name" value="MITOCHONDRIAL GROUP I INTRON SPLICING FACTOR CCM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46128:SF329">
        <property type="entry name" value="MITOCHONDRIAL GROUP I INTRON SPLICING FACTOR DMR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042154359" evidence="3">
        <location>
            <begin position="20"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="272"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1735856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="676" mass="75652" checksum="69B0BE0AFA104FFD" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZ73</accession>
    <name>A0AAD8XZ73_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Histidine phosphatase family protein</fullName>
            <ecNumber evidence="1">3.1.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012924</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZ73"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF10">
        <property type="entry name" value="2-CARBOXY-D-ARABINITOL-1-PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1736324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="195" mass="21847" checksum="BE909CB60A46E95D" modified="2024-05-29" version="1">MIENTSRRFIIARHGETDFNRERRVQGTSNDSVLTDKGISQATALGVYISKRDRITRTFCSPLRRCRQTYAEISGGGAANDNPGLPEPTILENLKEIELKEWQGRLRNDIIIEDKTNWDIFKANPCSLRLQNGTFAPVLDCFERAISNWDVIRSDAASNSADVTFIMCHGAIGQCMLLQALGLKKGVWQIPSICT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0G3</accession>
    <name>A0AAD8Y0G3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">1-alkyl-2-acetylglycerophosphocholine esterase</fullName>
            <ecNumber evidence="1">3.1.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_012186</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.47" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0G3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003847">
        <property type="term" value="F:1-alkyl-2-acetylglycerophosphocholine esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272">
        <property type="entry name" value="PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272:SF0">
        <property type="entry name" value="PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03403">
        <property type="entry name" value="PAF-AH_p_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042168463" description="1-alkyl-2-acetylglycerophosphocholine esterase" evidence="5">
        <location>
            <begin position="21"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1737319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="419" mass="44890" checksum="512128A2458803AB" modified="2024-05-29" version="1">MKHPFIIALCLSAAFHVIDGFTSCDPQSTPLSRRSSTMHMLPPTLLSGIDDATTLLTRSQAITYPLGFLAAFRTGAAISVINQPQMPKLVNAAIGSTVLRLPTYGTRVRLFYPTTSEAFNDSNAVMAPYCTDGLQTSNGMARLVKFDALGLSFLLAHLANASSGCVADGPIDKNTLDGEDLPLLVYSHGYGGNMDMATYFFRTMASKGIIVAAVEHTDGTASSTILPDGSERKFNEYLMTGRQQLTRRASELLEAVEFLPKELERIYSTKVGTTMVGGHSYGAPSAIMAANGAAEDSRIAGLILHDPALGMGYGMLPPNGAKSKIPSVTYTSDEYNKAKVRYGDLTLHVRGAYHGNFVDAPLWAPSVVMRTLSLLIPAAGPSNPVEVHEELAESASEFIRNKNPASPTVQSGKLFEFIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0Z1</accession>
    <name>A0AAD8Y0Z1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Exonuclease 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011688</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0Z1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF9">
        <property type="entry name" value="FLAP ENDONUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="314" mass="35643" checksum="DF2113764447881C" modified="2024-05-29" version="1">MGISDLLPHLPGGKSYLQDFYELRMEQNAVPIDAAGLLWQCALMHSSEYLSGNLLPALIEWTQHLNYFRSICQWKMRLYLDGMNNPHKEFENERRRLRRDSAEHEHGRIRNTPEYLAQAAWIAKNVLKIPCYISKEEADPQVAYEAVSKGLVPVTGDSDLIAYGAVKVILVKSYSRGWYRVIDLEVDTEPGEYPLYDLYKDNGVIVFQLYAGCRGCDFTNEECGIKGIGFTAFMTIASAVEGDLNALTFSKAMWSSDNTKQIALDNQMESVEQVETYLQHIINIFSDATIYDEQSNTITMKGMTVEEATDVLEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1M3</accession>
    <name>A0AAD8Y1M3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1M3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="247" mass="29065" checksum="361F52C9E84B7369" modified="2024-05-29" version="1" fragment="single">DEDDDFPHAKETFFHTSRIKDSIAVQKHHGTNDCEVHEENPHLQDFMIPHHSVHVRRLDEEEEAAVTVTIAETAAEQPVNAAAAATTRRSCLRPETKTSYYNRPKTEKSKRRIHFGDVFVRDYEMILGDNPCVTYGPPVTLDWDYVEFNPLPVDEYEFHHPPRRTIREMGMNYYRRKELLTLAGHSEEELKMAKKEVKKCKSNRYMTRQLASYPVVKMQATIESALRKCRRLLKDDHWKTERHLFVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2P1</accession>
    <name>A0AAD8Y2P1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_010561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2P1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1738531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="131" mass="15595" checksum="7A7DB49D59FFBBB7" modified="2024-05-29" version="1">MDIVSRFLLSFSLQPCKIFMSHPDLDMEPLFVYKLKCLPLVVEWFRRSKQLCGDNVGCWKQSVPELRSRELSAVYKFVRDMHLLASDGYWNNVLNDSQAEKLRIQVEKRKLELMLLRADEKEKCAMKRLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3A0</accession>
    <name>A0AAD8Y3A0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010773</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3A0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="310" mass="34967" checksum="023C23A1664DD272" modified="2024-05-29" version="1">MPSPLSPPSRSSYGSDSSSSSTASSISDFRFERINFKKLLNSYFSRWDKKRITEIDVLLKRNEGKEAKLMLMLAKRYDTSNPLNAVYVKYHTARLSKEQLDDFAALATVYLSVFRPSDLAEVDNLLEKYKGKEDELFSKLATNFHAINPLKIRKIEQNIDYKQALVDFFEQHDVSKVEEVDGILAKSVGKEAILFSVLAEKYRAMNGLDPLLTARLDGSDCNDYVSLLQLYLAIFHPACTSSAESMLSRYGLGRESELFAKLSDKFRSTNPLSICKIVNKSNDTVTKHVCLDNTSCLSRPLPQSPMIATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y641</accession>
    <name>A0AAD8Y641_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008519</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y641"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="200" mass="21842" checksum="B2A4C6BF7D2C7597" modified="2024-05-29" version="1">MPKLHYVSKRFLKKEGYRECLANGQRIQGQDADQVQVNDTTTINNATKSVVGESNINQQGGGGSLLNGNKKEKSKINNGATGLKRRRPDVEASSAIDLNQTNGSGNHNQGPANSTMSVAPAAAAAGASVNLVRRNQNIIWVRIGLTDHPAFELYNPDNPDNDGSTVWVQYTSNGVNECVSRSQIKNGLQDRKRHRPTYYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y654</accession>
    <name>A0AAD8Y654_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcription initiation factor TFIID subunit 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009883</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y654"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051431">
        <property type="entry name" value="TFIID_subunit_9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48068">
        <property type="entry name" value="TAF9 RNA POLYMERASE II, TATA BOX-BINDING PROTEIN (TBP)-ASSOCIATED FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48068:SF4">
        <property type="entry name" value="TATA-BOX BINDING PROTEIN ASSOCIATED FACTOR 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="394"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="417" mass="43523" checksum="E8E6632C55A96847" modified="2024-05-29" version="1">MAANPTAAPPTTAATTTSSTNNPTPSISPIKKTTSSSNKSPTSSKSKHSSSDHVKFTSTTSKKSPTKKSSTTSSTAATEKQLKLQKAEIAKPAFRQDVEVWAGPSNVVFPRRYHSLMQLKQTNSNNSSSGGGGGGNTKKKENRNGKGNEVYYGSQSQGWMYGDGFARMGGLSWMDSDAANTATQQPQSSSSSSSSGFLMDDVSIIDKSLHSAGLTRSHLTPRAYACLLEQARRYTLELLADAQDYALHAQRSGSGDNSSMIAALQPSDLLLAVEMREDTNVCGRGGESGTVAKYTEECYGGVVLPPVEEQLTARTFDVVNGARVVQRMMRGGDYPMGLSEVGNLGKKGGGSGGRKTGSYGAATGRQISVNLKSGKVIDEKSKSGGSSVVGGGSAASAPAASKTSSGSKGQKRRLTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6T3</accession>
    <name>A0AAD8Y6T3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6T3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="17"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="373" mass="41935" checksum="60C50C3AD2F7F8DF" modified="2024-05-29" version="1" fragment="single">RRSPTCTHKYQQWLRSKQVHVASNLVTTTNDTNLVVAGWGCVAKTDIEPGTVLFSIPRDACFGASVTENDDDDGEEEEDPTTRDTQMDLAMSILHCQNQQYLDNNNEAKAKEDWSPFPLSQFTHSTTSRSSLDVGTRIPSCHAHPSGFISLILDVAYKHYFNSHTNPWFGVSIVPFNTTLNWGKVPNVEFDLEEEDDNPDYNNNSETLCQRIVGRASCNIKKGQELFQAYGTSVADWCIGMVLHRQNWKIATVWTEMWCQLTTDILYIAQEAKEKKKKGKTHSINSETLNLNTRRQVGSEESDNPFASKTKIPQLASRLDALKSSGAVDESPWDGLDGHWTAEIARPTQPFLQSLRVSSQAKNHPKRGRENGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y714</accession>
    <name>A0AAD8Y714_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009323</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y714"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="666" mass="73257" checksum="4CF12CF94C30F425" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7H7</accession>
    <name>A0AAD8Y7H7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">15-cis-phytoene synthase</fullName>
            <ecNumber evidence="2">2.5.1.32</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_008547</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 (2E,6E,10E)-geranylgeranyl diphosphate = 15-cis-phytoene + 2 diphosphate</text>
            <dbReference type="Rhea" id="RHEA:34475"/>
            <dbReference type="ChEBI" id="CHEBI:27787"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58756"/>
            <dbReference type="EC" id="2.5.1.32"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.32" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7H7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004311">
        <property type="term" value="F:geranylgeranyl diphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051996">
        <property type="term" value="F:squalene synthase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00683">
        <property type="entry name" value="Trans_IPPS_HH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019845">
        <property type="entry name" value="Squalene/phytoene_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044843">
        <property type="entry name" value="Trans_IPPS_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033904">
        <property type="entry name" value="Trans_IPPS_HH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31480">
        <property type="entry name" value="BIFUNCTIONAL LYCOPENE CYCLASE/PHYTOENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01212">
        <property type="entry name" value="Phytoene_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01018">
        <property type="entry name" value="Squalene/Phytoene_Synthase_Lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01044">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042244358" description="15-cis-phytoene synthase" evidence="5">
        <location>
            <begin position="19"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1740452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="330" mass="36943" checksum="BABFF9F538FA7CEA" modified="2024-05-29" version="1" fragment="single">TRRFCILLATTVLSKCAGFSFRTSNSCTHRRMPALHHHRSSSTTNPDEAIKELMKTHDPILLFASRLLDADTARDASALYAWCRRLDEITDDPSSDVATIQQRLSDWERRFDMICRNEPVDDMDRALAMYIQRNDDLELSPFVDMISGMKEDTVQNRTISNMAELDEYAYQVAGTVGLMLLPLLKANVEQSRDAAIALGKAIQLINILRDASPDVALGRVYLPQDMLKAEGVSTEDVLQLKSSPEYRKVVAAVADHAEALLIEAEIGKSTLPGVGPLFVQIIVELYREYLIKLEQIGYDNLNLSGERVKIKTIQKLVASFKAATKVLTQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y851</accession>
    <name>A0AAD8Y851_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pentapeptide repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y851"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044213">
        <property type="entry name" value="At2g44920-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47200">
        <property type="entry name" value="THYLAKOID LUMENAL 15 KDA PROTEIN 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47200:SF2">
        <property type="entry name" value="THYLAKOID LUMENAL 15 KDA PROTEIN 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041963759" description="Pentapeptide repeat-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="222" mass="23183" checksum="78BCBA9FF6A4FC65" modified="2024-05-29" version="1">MMKSASLVLIALSIPASHAFQASRAGISIQKVHSSTPTSISLFPTTENDIKSTSDASSPLSSITAAAAAAALFLATAIPANAVSGGGLDYAGLDISNQDYSNGNYKGKDFTQVLAKATTFANSNLQGCRFYKAYLVNTNFENADVRGVSFEDTSMDNANLKNIVAGGAYFGQSLLDVATLEGGDFTDAQIPTKTLLQVCDREDVKGTNPVTGADTRDSLMCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9H0</accession>
    <name>A0AAD8Y9H0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_007905</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9H0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11046">
        <property type="entry name" value="CYP97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002402">
        <property type="entry name" value="Cyt_P450_E_grp-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF50">
        <property type="entry name" value="BIFUNCTIONAL ALBAFLAVENONE MONOOXYGENASE_TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00464">
        <property type="entry name" value="EP450II"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042018585" evidence="9">
        <location>
            <begin position="25"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="674"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="688"/>
            <end position="697"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1741427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="697" mass="78072" checksum="A723C01890D6C75B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9H4</accession>
    <name>A0AAD8Y9H4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006849</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9H4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="1">
        <location>
            <begin position="77"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="401" mass="44481" checksum="8F8897F8CF04F5FB" modified="2024-05-29" version="1">MSTTSPSCRSSTQHLADIVVTAAESSQKINNQIFNIAQLRVSNMQLHGRDDDIKLLRSKLRELAEKKDVGDEEYAAKSRAGEMVLVSGTSGTGKSALIHKGLGNPAAKSGYIFASGKFEDKFHRPLSAFSDAMTRLAKFITVDHNKMGKLSSGGQSIATLIRNKIQNEFEVEDAKQLRRVLPGCAELLGLGSRRRSKFSSFLCPSSHAAKEALFRSAPQLGSAKRRLQVSLALAGKESIAKMHYAVRRLLKIICSHLKGVVLFIDDLQWSDTATLDLLKSIVLDGEIPSLLIVGAYREDEVPDHHPLAFHIRELEQMNMSITKIRIGNLSVGYAIPLVAEALGMDDDDSKVKSLAETIHRKTEGNPFFMLMFLRSLYDEKLLQYNFGAMKWTWTTMQSAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YA40</accession>
    <name>A0AAD8YA40_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Chitinase</fullName>
            <ecNumber evidence="6">3.2.1.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_006887</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YA40"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06548">
        <property type="entry name" value="GH18_chitinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF317">
        <property type="entry name" value="CHITINASE 12-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH18" evidence="5">
        <location>
            <begin position="177"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="587"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="680"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="808"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="592"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="612"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="654"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="707"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="817"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="827"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="837"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="867"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="880"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="902"/>
            <end position="917"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1742322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="917" mass="103204" checksum="008CCBA9C8F33BBA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YA50</accession>
    <name>A0AAD8YA50_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_007408</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion inner membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the complex I NDUFS4 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YA50"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.190">
        <property type="entry name" value="atu1810 like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006885">
        <property type="entry name" value="NADH_UbQ_FeS_4_mit-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038532">
        <property type="entry name" value="NDUFS4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12219:SF8">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 4, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12219">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04800">
        <property type="entry name" value="NDUS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5 9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1741835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="278" mass="31040" checksum="CE702376C9E56D6C" modified="2024-05-29" version="1">MMSATVARRAQRSLSLLAKRALSTPAAAPSRQAPSAKALAVAEFDSEYVQNQAHLEGEKSEIQKYQEQMNAIDRHAVFAVTTPLPDPVLPENKSEIAALDSAHKNQIPLTPEGHEKIVVIKQEQAKWPGQSPLGKEQAWVISFQDQGETAETWNNPLMGWVSSADPLANNMRLQMSFATAEDAKYFAEKRGWKFIIEAPIIRKGRDDDAQYQDVFLPQAVAGAIKREGHKCDQWYRDAAGASHYFRPLKYHGDGTVRQHGPEREAAVAKDAESYYKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAG1</accession>
    <name>A0AAD8YAG1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phytanoyl-CoA dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007597</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAG1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883:SF46">
        <property type="entry name" value="PHYTANOYL-COA HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="653" mass="73440" checksum="AA3BEABFCF22E321" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBB1</accession>
    <name>A0AAD8YBB1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007173</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBB1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052943">
        <property type="entry name" value="TMTC_O-mannosyl-trnsfr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44809">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44809:SF1">
        <property type="entry name" value="PROTEIN O-MANNOSYL-TRANSFERASE TMTC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="86"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="325" mass="35648" checksum="E4E9E767D1A55658" modified="2024-05-29" version="1">MLPQVDLKGFLHHVEHVRRLKNRGAELRTSGDLTGAVNHFKWALALNPRCTTCLKDWAEILLSQKNFVEAEKKIRNALELLEGQDSDALFTLGLILSEQGKDDESIAVYKKSVELNGEDAELCYNLGIKLGEQGDTKGELAMYKKTVSIDGNFGGAYINMGTILASSGDLASAEVMFLKAIQCSEEVRTKGMFNLSLLLQQKANNLATSGNLEEAKAAIIEASKLLDDAKPLIDARIALGGSNSEDAMYASQFKPMRVQCHRVLGQVMAGMGDMVSCEQEFRIASEKFPDIPGIWAALSRVLEIQGKMDEAQVCKAKFEALQNLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBJ4</accession>
    <name>A0AAD8YBJ4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HORMA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005738</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBJ4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016035">
        <property type="term" value="C:zeta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.900.10">
        <property type="entry name" value="HORMA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003511">
        <property type="entry name" value="HORMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036570">
        <property type="entry name" value="HORMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045091">
        <property type="entry name" value="Mad2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11842">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11842:SF10">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56019">
        <property type="entry name" value="The spindle assembly checkpoint protein mad2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50815">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HORMA" evidence="1">
        <location>
            <begin position="15"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="295" mass="32710" checksum="541BE345F662FF6F" modified="2024-05-29" version="1">MASTNHANAVSSSSQQFTSLLGCTMESIIHELLYSRSIYPPDSYVHHRHLGVRFHCSRVPQVCDYISNFLKVAVPSIVSGVGDSISLVILEEEVANSNQSGTSGGQQQRIGATKTLERFVFQFQIDNIIYGEDTKPKHIALHNDGGNMLPMDIQHEAMKRDTELASEAKTQMERSMRDCLLQVLSLRGRRRSKDEKAENLSFKLCLHVAEEDMKQQQDDNDIVVASVSGKQCPELVTAVNQGEWFQPEESSCLFSTNANGNANGSKGLIRPIRHVNLPSCGIKMQMGFAVPSEQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBK9</accession>
    <name>A0AAD8YBK9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PAP/fibrillin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_007012</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBK9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039633">
        <property type="entry name" value="PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006843">
        <property type="entry name" value="PAP/fibrillin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31906">
        <property type="entry name" value="PLASTID-LIPID-ASSOCIATED PROTEIN 4, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04755">
        <property type="entry name" value="PAP_fibrillin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0934">Plastid</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastid lipid-associated protein/fibrillin conserved" evidence="3">
        <location>
            <begin position="3"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1742447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="138" mass="15209" checksum="072F8BFE9449CA40" modified="2024-05-29" version="1">MQTLFAELEALNPTLNPLKKASVNGDWSLDYTTSDTILGKGGFPRIGPIIQNIDTTTLSAKNSETVQYVLFPVPRSISAELSPVNGKLTDVKFKRFQLGPIGFDAPDSFRGSLDITYLDQDVRLTRGDKGNIFVLTRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBV4</accession>
    <name>A0AAD8YBV4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FHA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006207</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBV4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050923">
        <property type="entry name" value="Cell_Proc_Reg/RNA_Proc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23308">
        <property type="entry name" value="NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="3">
        <location>
            <begin position="50"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="201"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="477"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="539"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="388"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="208"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="480"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="600"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="634"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="651"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="661"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1743586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="670" mass="74465" checksum="E8599B91C4B3A354" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YC61</accession>
    <name>A0AAD8YC61_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">glutathione gamma-glutamylcysteinyltransferase</fullName>
            <ecNumber evidence="1">2.3.2.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_006068</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.15" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YC61"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016756">
        <property type="term" value="F:glutathione gamma-glutamylcysteinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046938">
        <property type="term" value="P:phytochelatin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010038">
        <property type="term" value="P:response to metal ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.30:FF:000001">
        <property type="entry name" value="Glutathione gamma-glutamylcysteinyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.30">
        <property type="entry name" value="Phytochelatin synthase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040409">
        <property type="entry name" value="PCS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007719">
        <property type="entry name" value="PCS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038156">
        <property type="entry name" value="PCS_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33447">
        <property type="entry name" value="GLUTATHIONE GAMMA-GLUTAMYLCYSTEINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05023">
        <property type="entry name" value="Phytochelatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51443">
        <property type="entry name" value="PCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0104">Cadmium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Peptidase C83" evidence="6">
        <location>
            <begin position="20"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1743447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="450" mass="50206" checksum="FF8AD5A308768689" modified="2024-05-29" version="1">MMAKSNDLTDSKNIAQPPTKPSRTFYRRTLPSSLTSFSSFEGKEIFASAMSTGGTSAFFSLIEQLQTQPEPAYCGLTTLVIILNALAVDPRRSWKGPWRWYEESMLNCCVDLDLAKETGITFSTFACLAKCQGLDVHAVHGSDSTVEEFRQIVKQTCTHQKLPSSFLVISYTRKVLGQTGTGHFSPIGAYDEASDNVLILDTARFKYGPHWVPLELVFEALIPEDPDTGQSRGYVVLSYDGKQDEIFNPDTCHRCNSHLPLSVLFGSKQNDSLRKEYKDFLESLLPNVTFSLVISFWTKDRTNDNYIWELVQPQLQPVDSADVDMVTSLRRLLKGLIARKQSDMPSALLLTWQWRNINNGNKSDVGCPPGGSCCTPSPNNGSVRTLEISPGEALYIVYLASLSKEQRRGIVYEDGIDAEMRIGVDDTVREQLLAETALVSYAIETCDWDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YC90</accession>
    <name>A0AAD8YC90_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006113</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YC90"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041908179" evidence="2">
        <location>
            <begin position="22"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="250"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="475"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="541"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="557"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="596"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="612" mass="60012" checksum="47D6CCD0D5344220" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCD1</accession>
    <name>A0AAD8YCD1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anthranilate synthase component 1</fullName>
            <ecNumber evidence="2">4.1.3.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.27" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCD1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004049">
        <property type="term" value="F:anthranilate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="entry name" value="Anthranilate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="AMINOBENZOATE/ANTHRANILATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236:SF9">
        <property type="entry name" value="ANTHRANILATE SYNTHASE COMPONENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="ADC synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Anthranilate synthase component I N-terminal" evidence="1">
        <location>
            <begin position="51"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="313" mass="34941" checksum="017C2B22AC7D7468" modified="2024-05-29" version="1">MCIMMLMNAMCDDDCDDYVSPFFEDGGAESGLTWGSDGAIERLVDLLDNRRGALLSSSYEFPGRYARWSLGFVDPPLEISGTGSNCKISALNVRGQVLLEPVMDAMNKLLESGTLSNISREGDVIDVQVSPLADVGTFSEEERSRQPSLFSVVRALVDLFGYDSEETGDIQLGLYGAFGYDLTFQFEPIDLAQERDPNQRDIQLYLADELVIVDHGRNSAWTVSFDFAYGEKSTKGLPHEGAAAPFLPFDEHPSNNGEFLDRDTPRGDFTKSVDRAKEEFKVGNLFEAVLSQTFRKKLTKKLLRRSCLDNYER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCD5</accession>
    <name>A0AAD8YCD5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCD5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="187" mass="21117" checksum="49BA9D8C8402B9DA" modified="2024-05-29" version="1">MTLAINNLGGYIPKKRSKCPRRRASVDGPSPYVAQQPLGRMPRRSSCPSLKKNVAFSEHSNIRIVQHSRDDSAIEKWYSSDDHLKFKIDRTVEVRSFRKQAEAAMKQVGAASLCPVGIEQFLSSKSLESTKLNRRLIIKKVLLEQTRQRALGFRDPDQLASVAEQVSTESLKGAQKRGKFQEMSKFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDR0</accession>
    <name>A0AAD8YDR0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005316</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDR0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1743719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="125" mass="14020" checksum="55A90C089804AB64" modified="2024-05-29" version="1">MICFRRAIIAAAIPCIDRTAAFAPFLSLPGGVSSFHRSLDQLRPHKMSTTDTDDGNSIWETEGTMVRMTCFRVVPREAEIELESLVQPSEEVEELAWIDSTFDMEKLTVTGIMIVEDLKEKGLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YE80</accession>
    <name>A0AAD8YE80_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ornithine carbamoyltransferase</fullName>
            <ecNumber evidence="2">2.1.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_003974</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.3" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YE80"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004585">
        <property type="term" value="F:ornithine carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019240">
        <property type="term" value="P:citrulline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:L-arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1370:FF:000009">
        <property type="entry name" value="Ornithine carbamoyltransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="entry name" value="Aspartate/ornithine carbamoyltransferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002292">
        <property type="entry name" value="Orn/put_carbamltrans"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00658">
        <property type="entry name" value="orni_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001986">
        <property type="entry name" value="PRK00779.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45753">
        <property type="entry name" value="ORNITHINE CARBAMOYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45753:SF3">
        <property type="entry name" value="ORNITHINE TRANSCARBAMYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00102">
        <property type="entry name" value="OTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="Aspartate/ornithine carbamoyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00097">
        <property type="entry name" value="CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aspartate/ornithine carbamoyltransferase carbamoyl-P binding" evidence="8">
        <location>
            <begin position="41"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Aspartate/ornithine carbamoyltransferase Asp/Orn-binding" evidence="7">
        <location>
            <begin position="193"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1744683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="352" mass="38525" checksum="0CEE8D2316F14CB5" modified="2024-05-29" version="1">MFSTLRYVNQPALSSAAKNFMKNGVAKRGMSIAALNGFEGKHFISIDQLSNEELRGLLDLSKKYRDTYGKASTVDPITAPKPLTGQSVSMIFQKRSTRTRVSTETGMTLLGGQSLFLGPSDIQLGVNESMRDTALVLSRFNSLVLARVFSHNDVLELSKHATVPVINALSDLHHPLQTLADLMALEDHFGDVKGKTLAWVGDGNNVLHDLMLGGAKLGMNIRVATPEGYEANEGILETTKKLAAENGTEDVFLTTVASEAVKGSDVVVTDTWVSMGQEEEYEQRVKEFDGYQVNANLMGQANPGAVFLHCLPRHREEVSDEVFYSPQSLVFPEAENRMWTVMAVMAAQLGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YES2</accession>
    <name>A0AAD8YES2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF285 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005694</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YES2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005046">
        <property type="entry name" value="DUF285"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03382">
        <property type="entry name" value="DUF285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="331" mass="36381" checksum="49F82289B54674F0" modified="2024-05-29" version="1">MHIHPIIAIKMEPAVVTDALGEQAAANATAATATGGDVIATVSNETKAYKECPLDKYGCYCCEDEYDGSIFNFTCRTDHHGRYCCGETCGEEDIHSSTSCFTSRDQLRQAVVEYTSSNITISNAAYQTYGNMSDWCVSPLDDMNAVFAHLPPSFNENLGKWDVSNVKNMSFMFDGAFSFTGDDLNQWDVSHVIDMRGMFADACCSFNANLFKWNTSSVLEMSQMFENAQIFNRDVSMWDISSVKNMDKMFLGAQAFNQDLCAWGRGSSGAFPYSAVTDIFRDTACKFEDSPVEANKGPFCASLCDLTSSSSMTHLASLSVALSLVISFLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEV0</accession>
    <name>A0AAD8YEV0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005508</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEV0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="166"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="340" mass="37450" checksum="91779EC2E9A40EA8" modified="2024-05-29" version="1">MRMYFDKALMSSASFLSSHDASENDSGENDENDDNNNPLSSPSAVSGAARAAAVADSLRCRQFECLPIFLEEKPKRPNNIEGALEAKPTDSNATKKVKDALKKQEQEKANAYMGVVQLMNYDKFAYGALNDADSVTTQSLETYWKSLARAQTPSAEEDLFSETEDSSSFFLPEPSSSISSTPTSTSVEAVQMMEYHLWRSLDNMLRLLSMVSSASVPLPSQLMGLLPKRDDWPQDFLLEGAATSLENSGGNIGTSFKSPFVRVDQVAASSSKYSPLRRAHRLSYVIWMLLDGLSITGNDQPTRRDVLKMTSVLARLEAAKRTIDGVNDILKQLIPPPKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFY0</accession>
    <name>A0AAD8YFY0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_003685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFY0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1745761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="156" mass="17817" checksum="D7E5808065E86844" modified="2024-05-29" version="1">MNIPSPSALPRGHTRRSVSFSLISFFGSPPTHELQDLKDGMWYTSEDEDQFKADAQKELDAFKLLKERSLDEAEGEENSPQHQDMCIFGLEQYLISLDHTRKRARAKKLTKYAVLDAQARGFGFEQIAETARRYSAWSVAQAKMVGDFQCMMCNDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YG62</accession>
    <name>A0AAD8YG62_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Redoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_003820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YG62"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1745896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="98" mass="10857" checksum="4FD007F0FB073C74" modified="2024-05-29" version="1">MNAWAEDQMINPNGMIQFMGDPEGALTRTLDMELNHPGPHSVGIIGRCKRFAIYAVNGEVKYVAVSEREDDPAGDDYPEDTLAEALLDAILKHKNDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGC1</accession>
    <name>A0AAD8YGC1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGC1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="126"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="287"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="383" mass="40765" checksum="E009206018D91DC9" modified="2024-05-29" version="1">MMNGNNSDNKGSQKETEKKSTQLAGFAPASRGTTSMKSSSSASGAAQASSSTAAAPSASSDGNNVDTTNRITTTKKKAAATKKRSKSSSKAIAAAGGSSGGIDTTATHNNHNSNETEDTTIQPIDPSSMNSSSFQPMSLSQIQLRIKLLLDKLPSALPEVPPDYINPDETIHNNNNQQSSLYHPPIKSFASALQTTIEEYNLLLSLVSSATYQWGVDRSGASQQNLSVMNSELQQCQEVITSVVSGRLSNVLCPAVDVLVGRVEVVKGGNNGGEENGSSSKKRKLDTSSATTTSNNATTDRLLGTTATINSTTTTNEQRINHYTRPLVDPSYVHLCHQIVARNGEMLRYTLATCIHTAQRVIGDYLEVMKKDVGHEANKGGYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGD1</accession>
    <name>A0AAD8YGD1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Short-chain dehydrogenase</fullName>
            <ecNumber evidence="3">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005179</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGD1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43639">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G02870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43639:SF1">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="270" mass="28632" checksum="C69AC73AF53E95CC" modified="2024-05-29" version="1">MHSPALSTTHLADSDSTQGLGLEIAHQLKNNGAAALILVPRSDDKAIKAMEYLSPATAALDNCVIEFIKADLSNVEQTEAVIPRSILALQKAVNAAATTARGNLATTTAASFNEQYDTNVRAPFLITKHATQHMMEMNLERGIGSIVNICSVASKGGAPFILGYSCAKSALVTLTKNNAAELAPKGIRVNGVDMGWCLTENEDKLQSANAGADWWKNADESVPLGRILRPVDVAASVLFLLSGASVMMTGSIIAQRTLLTDDILEDIPQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGH9</accession>
    <name>A0AAD8YGH9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005183</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGH9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47988">
        <property type="entry name" value="SOMATIC EMBRYOGENESIS RECEPTOR KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1007" mass="110805" checksum="F58D827FD8DACEE9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHG8</accession>
    <name>A0AAD8YHG8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHG8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="225" mass="24800" checksum="96722B7301FE685E" modified="2024-05-29" version="1">MPRSSANDDPRFRKAARKIIENTTITAHGGQKPSSITVDASMMSSASTVTATPPLKTKLKAKKVRYSSAAAQQIRKNNLVDKETKKQATTDATQLYADSQKPGEKQLSAREVKEIVEKKLDVSVSKRIIQKHRITVPHGQERIDAISKAATHGKLFHAYANWTDADEQNLLTLTTKPISIGDTSFENGTPAAINHMSKEEREEIRNKMNAADDMEVDVEPAPIVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHY3</accession>
    <name>A0AAD8YHY3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_002218</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHY3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045877">
        <property type="entry name" value="ZFP36-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547">
        <property type="entry name" value="CCCH ZINC FINGER/TIS11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547:SF18">
        <property type="entry name" value="PROTEIN TIS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="131"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="184"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="131"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="184"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="78"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="660"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="106"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="673"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1746874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="763" mass="84959" checksum="A449C3719F568B61" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YI06</accession>
    <name>A0AAD8YI06_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Adenylate/guanylate cyclase domain-containing protein</fullName>
            <ecNumber evidence="4">4.6.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_003581</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YI06"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43336:SF3">
        <property type="entry name" value="GUANYLATE CYCLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43336">
        <property type="entry name" value="OXYGEN SENSOR HISTIDINE KINASE RESPONSE REGULATOR DEVS/DOSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="3">
        <location>
            <begin position="149"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1745657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="507" mass="56537" checksum="7F067A4E082BCCFB" modified="2024-05-29" version="1">MEVITVSDASFTYSMTSVFDITGRVREEAILAILLTSFVIFLLGLGMVSFTKDVHNLVIVPIEHMIQLVREISENPLGKDLSLRAVDNNKQKDDGMETTLLIRTISKIAGLMRVGFGEAGADIIGKNLNITHGADAMNLLGTGRKIHSIFGFCDVRQFTDTTECLQEEVMLFVNRIAHILHSIVVQCDGAANKNIGDAFLLTWKVNTSTDPQQITSCADHNYAADKALFSFVKTMIEMIKHEDFLCNFSPRALAELYERMPGYKCRIGCGLHFGWAIEGAIGSSKKIDASYISPHVNMSESLEGATKDYGVPILMSEPFYNLLSSEAAAGCRKVDAIKKREGDIVTTNLYTYDVDLSIDFAHEEGKKKETKKKNEKARKKKRPMIGPAPAQRKTQFSLVDDHRAENQRKTFLQRGNNNENISDGLGQLPRIKISNNFPDVWNSDEDILQVTAHFTDEMRAIFSDGMDAYIAGDYDEAKLFFYQVLDETDGNDGPAQCMLAKLTRVTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YI50</accession>
    <name>A0AAD8YI50_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="4">PPIase</shortName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_003641</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YI50"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01926">
        <property type="entry name" value="cyclophilin_ABH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000013">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="5">
        <location>
            <begin position="69"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1745717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="227" mass="24232" checksum="F796072A31AC9744" modified="2024-05-29" version="1">MTSGLLCAGHLSVTTYDHALFLSTSLQRKVDQKKRLFCGYSRLHFSARNLLPYISNDKSNDITSNPKVYFDITIGGKAEGRIIMDLRADVVPKTAENFRALCTGEKGFGFAGSSFHRVITDFMCQGGDFTNHNGTGGKSIYGNKFADENFILKHTGAGILSMANAGPNTNGSQFFLCTVKTAWLDGKHVVFGSVVDGMDVVKAVEGVGSGSGATRSPVVIAACGQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIV8</accession>
    <name>A0AAD8YIV8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">methylmalonate-semialdehyde dehydrogenase (CoA acylating)</fullName>
            <ecNumber evidence="2">1.2.1.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_003804</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.27" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIV8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004491">
        <property type="term" value="F:methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:L-valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006210">
        <property type="term" value="P:thymine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07085">
        <property type="entry name" value="ALDH_F6_MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000002">
        <property type="entry name" value="Methylmalonate-semialdehyde dehydrogenase (Acylating)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000003">
        <property type="entry name" value="Methylmalonate-semialdehyde dehydrogenase [acylating]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010061">
        <property type="entry name" value="MeMal-semiAld_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01722">
        <property type="entry name" value="MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43866">
        <property type="entry name" value="MALONATE-SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43866:SF3">
        <property type="entry name" value="METHYLMALONATE-SEMIALDEHYDE DEHYDROGENASE [ACYLATING], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="5">
        <location>
            <begin position="104"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1745880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="604" mass="65222" checksum="0341BC67A1C4056D" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJ61</accession>
    <name>A0AAD8YJ61_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003047</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJ61"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="67"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="16"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="105" mass="11612" checksum="6188065AE99E5F45" modified="2024-05-29" version="1">MSSNKKATALGTLTNHDGKRALSSDDAKDVARPTKKLKSHNRTMTIEAAQNQLDGSASEIAKKDRIIQDRTREIAALNSQLATAERSLTIATNAKKRLKRKMPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJ82</accession>
    <name>A0AAD8YJ82_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002347</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJ82"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="38" mass="3643" checksum="68D6946AD012F1E1" modified="2024-05-29" version="1">MQADGDTEGDALGLAEGRAEGDSDGSNDGTSLGATDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJ86</accession>
    <name>A0AAD8YJ86_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase</fullName>
            <ecNumber evidence="4">4.2.1.134</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_001554</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a very-long-chain (3R)-3-hydroxyacyl-CoA = a very-long-chain (2E)-enoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:45812"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:83728"/>
            <dbReference type="ChEBI" id="CHEBI:85440"/>
            <dbReference type="EC" id="4.2.1.134"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the very long-chain fatty acids dehydratase HACD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.134" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJ86"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102158">
        <property type="term" value="F:very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030497">
        <property type="term" value="P:fatty acid elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007482">
        <property type="entry name" value="Tyr_Pase-like_PTPLA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11035">
        <property type="entry name" value="VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11035:SF3">
        <property type="entry name" value="VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04387">
        <property type="entry name" value="PTPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0456">Lyase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="14"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00036671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1747591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="783" mass="85280" checksum="6A9BB00AF04BC62C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJV3</accession>
    <name>A0AAD8YJV3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DnaJ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_001887</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJV3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051434">
        <property type="entry name" value="DnaJ_C_subfamily_member5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44027">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44027:SF7">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0564">Palmitate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="339"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="7">
        <location>
            <begin position="72"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1747924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="357" mass="39408" checksum="75E67567401B32EE" modified="2024-05-29" version="1">MSDESGSAGGGGDDLSSLSGFFFYVFIVHPATAWILKPGRFDRKKSIMYAIGFLALLAAVKTGMEMQAKGPNHYSLLNVSRNSSPLDIKRAYKKLSLQLHPDKNPNDPNASSKFDRVKKAYDVLIDMEYREVYNKFGQDGINSSKRFDETQFFMELGVFYVTWGIMAYVLTLGKRSSLGRQWTFTGLIVMLVVEITLMTSQGSPFPSWFMPQNTEYEAVWLLHTLFPALMNGCRSIGSYLYVDLDAQTRQLLLALQEQNKDILLVLRDVQIGVQNVQATGGGGGGGRLATAGVVPPVGATARATPTGKIKELQDRLQVSNSTVQQAVGQLKSEKSNSNFGFYAMILGYVAFSYIFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YK01</accession>
    <name>A0AAD8YK01_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002114</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YK01"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="91" mass="10071" checksum="2D9FFC1A82AB2232" modified="2024-05-29" version="1">MNDGGEEPNSHEQPLESYAAFNRHGETAQAQGEYGSTPFFGTTHDPAEEEAYFFAHLDTATARNGKAPRMASRRSSDHVDAQLKKKPILHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YL91</accession>
    <name>A0AAD8YL91_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP synthase subunit gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_000628</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="9">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) and CF(0) have multiple subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ATPase gamma chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YL91"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12151">
        <property type="entry name" value="F1-ATPase_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.80:FF:000001">
        <property type="entry name" value="ATP synthase gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.80">
        <property type="entry name" value="ATP synthase, gamma subunit, helix hairpin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035968">
        <property type="entry name" value="ATP_synth_F1_ATPase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000131">
        <property type="entry name" value="ATP_synth_F1_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023632">
        <property type="entry name" value="ATP_synth_F1_gsu_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01146">
        <property type="entry name" value="ATPsyn_F1gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693">
        <property type="entry name" value="ATP SYNTHASE GAMMA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693:SF22">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT GAMMA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00231">
        <property type="entry name" value="ATP-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039089">
        <property type="entry name" value="ATP_synthase_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00126">
        <property type="entry name" value="ATPASEGAMMA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52943">
        <property type="entry name" value="ATP synthase (F1-ATPase), gamma subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00153">
        <property type="entry name" value="ATPASE_GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="7 9" id="KW-0139">CF(1)</keyword>
    <keyword evidence="4 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1748689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="307" mass="33395" checksum="DAB1820FAA067807" modified="2024-05-29" version="1">MLPRIAQHATRAAARAAPRSVIARGMATEKQIWNQIQSTKNIQKITSSMKMVSAAKLKGDEGRRMTAISFNNWADALNGPPQVVEDATFEELPQRSLIVTLQSDKGLCGGINSFITKSVKNCVAALQKQGKEADIAVIGDKGRGQLRRAYPELIQVSMTEVMSPGNFTLASALASELIAAGAGDYDAVVLMYNSFKNAATYTQMYKVIKPFSGEGEDEPLLAYEFEPDTKSEVLTDLQEYLLTSQIYHSWMDGAAAEQGSRMTAMENASKNAGELIGSLTLKYNRARQARITTELIEIISGASALED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLF6</accession>
    <name>A0AAD8YLF6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">6-phosphofructokinase (Pyrophosphate)</fullName>
            <ecNumber evidence="7">2.7.1.90</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_000733</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.90" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLF6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047334">
        <property type="term" value="F:diphosphate-fructose-6-phosphate 1-phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050929">
        <property type="entry name" value="PFKA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005121">
        <property type="entry name" value="PRK06555.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45770">
        <property type="entry name" value="ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="Phosphofructokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphofructokinase" evidence="6">
        <location>
            <begin position="8"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1748794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="409" mass="43972" checksum="FDF54DA886E42220" modified="2024-05-29" version="1">MSAAQHMNVAMMTSGGLAPCLSSSVAYLIEFWASALKEGKISGLNIRMYVDGYKGVLTGDSTVISPEIYDECACLHDLGGSPIGNSRVKLTNVKDCMARGFVKEGETPLEVAAQQLIKDDINVIHTIGGDDTNTQAAELSKYILEKHGGKVVVVGMPKTIDNDVYPIVQTFGADTAAEQGAIFFKNVVSESSANPRMLIIHEVMGRDSGYLTAATARKYRDGMKSAKFTGPGFTTTAKSRDIHAVWIPEVSLDIVEEGKRLRKVMDENGCVNVFLSEGAGVEDIVAEMEANGEEVPRDAFGHVSLAKINPGVYFSKRLAELVGAEKTLVQKSGYFARAAASNTFDRQLIKDCAKEGVASAIAGVSGCMGQDEDKAGTPIRAIEFERIKGGKPFKPELPWFKELLADIGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YM06</accession>
    <name>A0AAD8YM06_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000382</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YM06"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="199" mass="22271" checksum="49DA3DB2D543C208" modified="2024-05-29" version="1">MIATSNEMERLQKLPTLSKEISSPRKQPADAPIRSKSGPSPTSNKRRSPLVIDTKDDRESERNDGDANRVGTPTQTLSPTTAALSKLITTYAAKRVTNNASCRIKLRRRSLALSNSLTQSMESLRQSPGQISLSIRRMRQQQEVCLIRENLHGLARLCSSNRQARSICSIVLCQTKLRTVTTVMESDVNLQQQSFQNYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YM82</accession>
    <name>A0AAD8YM82_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YM82"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37384">
        <property type="entry name" value="OS01G0835600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37384:SF1">
        <property type="entry name" value="OS01G0835600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1749181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="687" mass="73816" checksum="4B879DFB6AEB139D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMD6</accession>
    <name>A0AAD8YMD6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_001868</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMD6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="635" mass="71414" checksum="9D9E70BACD2160DB" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YP98</accession>
    <name>A0AAD8YP98_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_001079</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YP98"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="5">
        <location>
            <begin position="113"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1749140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="336" mass="37616" checksum="61E3324F4DA25B1A" modified="2024-05-29" version="1">MVGPDDVESWLATLRSGECLSERSLRQLCQAASELLMEESNVQPVSSPVTVVGDLHGQFFDLQHLLSPEVGGEPPGSSYVFMGDFVDRGHNSVETLSLLLCLKLKFPGHVTLLRGNHESRQITQVYGFYEECLRKYGNASVWRHCVQCFDTFCIGALIDGCVLCIHGGLSPDVRTIDQIRAIDRQQEIPHEGAFCDLVWSDPEERLTNCPWQVSPRGAGYLFGARVTDEFAHVNNLDLIARAHQLVMEGKQYHFPNKNLVTVWSAPNYCYRCGNVAAILTIGEDGQETKENEIVEVEGGEKDNGAIRQSFKFFRETEHSQHGPKGEDRAQLVPYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4I5</accession>
    <name>A0AAD9D4I5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000045">
        <property type="protein sequence ID" value="KAK1733736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4I5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="195" mass="21739" checksum="2DE0229DC0D0D21F" modified="2024-05-29" version="1">MSGLSHFLQSKTQSTPFSLSLSLSTRGPFRKESTQSTCNKQKQKQDYVPPRNVAEIMSSANRHSHTSECRDDHDETASTSSSSTNNHQTERDDGTTPNEKSNVVFLHTNNSMMEMKPNRSGTTVYDANEGSSSSPRRRRRRRSEQSSPAISAMDGQDYNGNKDDPIDDEGWVSYAAATCVASCIPVLHFIQFFMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4I7</accession>
    <name>A0AAD9D4I7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WRKY19-like zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016566</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000058">
        <property type="protein sequence ID" value="KAK1732763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4I7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056866">
        <property type="entry name" value="Znf_WRKY19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24906">
        <property type="entry name" value="Zf_WRKY19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="499"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="418"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="707" mass="76416" checksum="DBC0C34F09FF5B57" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4M5</accession>
    <name>A0AAD9D4M5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA topoisomerase (ATP-hydrolyzing)</fullName>
            <ecNumber evidence="5">5.6.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Meiotic recombination protein SPO11-3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">QTG54_015398</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the TOP6A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4M5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042138">
        <property type="term" value="P:meiotic DNA double-strand break formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000706">
        <property type="term" value="P:meiotic DNA double-strand break processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00223">
        <property type="entry name" value="TOPRIM_TopoIIB_SPO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000387">
        <property type="entry name" value="DNA topoisomerase 6 subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1360.10:FF:000003">
        <property type="entry name" value="DNA topoisomerase 6 subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1360.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00132">
        <property type="entry name" value="Top6A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002815">
        <property type="entry name" value="Spo11/TopoVI_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013049">
        <property type="entry name" value="Spo11/TopoVI_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036078">
        <property type="entry name" value="Spo11/TopoVI_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004085">
        <property type="entry name" value="TopoVI_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034136">
        <property type="entry name" value="TOPRIM_Topo6A/Spo11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10848">
        <property type="entry name" value="MEIOTIC RECOMBINATION PROTEIN SPO11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10848:SF0">
        <property type="entry name" value="MEIOTIC RECOMBINATION PROTEIN SPO11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21180">
        <property type="entry name" value="TOP6A-Spo11_Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04406">
        <property type="entry name" value="TP6A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01550">
        <property type="entry name" value="TOP6AFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01552">
        <property type="entry name" value="TPISMRASE6A"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56726">
        <property type="entry name" value="DNA topoisomerase IV, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52041">
        <property type="entry name" value="TOPO_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11 14 18" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 14" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Spo11/DNA topoisomerase VI subunit A N-terminal" evidence="16">
        <location>
            <begin position="400"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="Topoisomerase 6 subunit A/Spo11 TOPRIM" evidence="17">
        <location>
            <begin position="510"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="122"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="286"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="286"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="304"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="14">
        <location>
            <position position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00082656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF21180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1733871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="686" mass="75902" checksum="82E52E3EA5ED5ED8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7H5</accession>
    <name>A0AAD9D7H5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 5A</fullName>
            <shortName evidence="4">eIF-5A</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_013776</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="4">eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-5A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7H5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045901">
        <property type="term" value="P:positive regulation of translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045905">
        <property type="term" value="P:positive regulation of translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000080">
        <property type="entry name" value="Eukaryotic translation initiation factor 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001884">
        <property type="entry name" value="IF5A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048670">
        <property type="entry name" value="IF5A-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020189">
        <property type="entry name" value="IF5A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00037">
        <property type="entry name" value="eIF_5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11673">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR 5A FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01287">
        <property type="entry name" value="eIF-5a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21485">
        <property type="entry name" value="IF5A-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003025">
        <property type="entry name" value="eIF5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01376">
        <property type="entry name" value="eIF-5a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4" id="KW-0385">Hypusine</keyword>
    <keyword evidence="6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Translation initiation factor 5A C-terminal" evidence="5">
        <location>
            <begin position="84"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1735613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="159" mass="17155" checksum="3B5BC6D2C6A6B53F" modified="2024-05-29" version="1">MSDNEYNIESVDAGASATIPMEAGQIKKGGYIMIKGKPCKVLSISVSKTGNHGHAKCNFLAVDIFTGKKLEDMVPSSHGTTVPVVVRSEWEIIDIGEDDELTLMSEGGDQKTDVNLPGYPEEMAQEIRDAWNEGENQVSVTVQAAVGIEQVIAFKKVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7U0</accession>
    <name>A0AAD9D7U0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012069</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7U0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="272" mass="30294" checksum="81C43071F94A58A1" modified="2024-05-29" version="1" fragment="single">LRSLVFHAGVETVGTRAFGKCPNLVSLKLPGVMTIEVGAFRVCTGLRLVEFGDKLDTIQDYAFYCCSSLRGVTIPSATCIGDGTFLQCTSLTDAVFGEGLESIGSNAFHGCRSLRRIAIPLKGGMFRSDFGYHQFGECINLSTVDLVGGIHETVASLHLEKWRNEMIEEINLINLVLPYAEEYNKPEEIVGWIVSVIHKIESFKAAHKELLKEATTLLELALWKANVEWIDDKEEQQVRITRGRAKRARREKHITSGASIVIKNVLPFLQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7V6</accession>
    <name>A0AAD9D7V6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2256 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7V6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017136">
        <property type="entry name" value="UCP037205"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37463:SF1">
        <property type="entry name" value="DUF2256 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37463">
        <property type="entry name" value="GSL3115 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10013">
        <property type="entry name" value="DUF2256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="283" mass="32248" checksum="C725F6B0B9913415" modified="2024-05-29" version="1">MVIQQLVRVSIYSSAFIHQGRPGPYTYTQHRYSIQRRCTSNSNSFINNEIDLEAMPRGVKKENLPVKTCTVCNRPFTYWRKKWEKVWDEVTTCSTSCNRKRKETNRQLNKTIHDSSNVEDPFVAIRENINIGCTESSIDDKEQLLNNMDSVLESDFDGEDQLLDSISGDMLAMEIGAQDDSSISESDAITDAKTKRKAEKKRKKAERRAQREGRGDPTAGQKQCTLCAKSVNLLIRCQHDKSGEWAMVCGKCWNDVSGGVVDGDDSHPYYRYGGLWKNRRAQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7W4</accession>
    <name>A0AAD9D7W4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">cystathionine gamma-lyase</fullName>
            <ecNumber evidence="4">4.4.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Gamma-cystathionase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_013306</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-homocysteine and L-serine: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.1" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7W4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004123">
        <property type="term" value="F:cystathionine gamma-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019343">
        <property type="term" value="P:cysteine biosynthetic process via cystathionine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808:SF15">
        <property type="entry name" value="CYSTATHIONINE GAMMA-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="TRANS-SULFURATION ENZYME FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="5 8 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1736170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="468" mass="50604" checksum="51F0FF63B0FC30F5" modified="2024-05-29" version="1">MQSIGRRLWQRCSCRQLSSSSSGRGKVEELSPAKAGSLAHQLREKLNNTKNCNESSLSLSTLLSHAGLSSSNGNSNAPLSPPIDLATTYERPADGNYGEGGLIYSRSCNPTRKLLQDAIGQLEVVSQHGQIIAPTFAFSSGMAAVASLLLAQKSPVKVLVPEDIYHGVPTQLHVCLNDHGIVHESVDMTNAYDIRQTIEHHIDSKSNAQHDGALVVWMETPSNPLCQVTDIQSICDLVNDVRCQHQNANIITVVDSTWAPPVITRPLLLAADAVLHSGTKYLGGHSDVLLGTISCSPINETGKFIAERLKSVQTSIGAVASPLECWLTLRGLRSLHVRVERQCQTAMKLSTYLDGHEHIVKVHYPGLTSHPQHATAKRQMAMYGGMLSFEVKNESMAMAVAGAVSTIRRATSLGGTETLIEHRASIEPPERRTSPPGLLRMSVGLEDADDLIDDLKIALDIASQICDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8B5</accession>
    <name>A0AAD9D8B5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Polycomb protein EED</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_012567</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat ESC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8B5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051243">
        <property type="entry name" value="PcG_WD-repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10253">
        <property type="entry name" value="POLYCOMB PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="174"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="220"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1736545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="460" mass="51235" checksum="105DD0049BBD56B0" modified="2024-05-29" version="1">MAAAIPSGYRLCASTNEDHDHPIYCVAFSPAVHQNDDDGSNKSALQCFSTCAGQYIHIYEVHTADNKQEKSLMVRQVYCDVDDEEEFYTCAFGGRGITEGKANNATINQSKAIYIGDNKGKQSKGTKRQRVNDDHCSTIHNLSLRQGPPLLCVAGKRGMIKVIDTVLQSLVMTLLGHGDSVNDLKCNPTNKDLLLSGSKDHSIRLWNLRHGQMIAIFAGHDAHRGEVLGLSWHYSGTKFASSAFDNTIKLWNVSDNSIAEQSEKEGPIQAAIRRSFEMERGDKFKAAIEQTPYFSTDSIHELPGCVDCVQFVGDLILSKSVQNVVVLWKPVVTNEDFATFNTIYPNYINENRKNNDRIKSKVIFLRDFTVDNCDNWFIRFGSPSPYNEILALGNHEGEVKVWELMGNEDDDEDQDYFGDNDGILCKLKTGGSTVRMVAIAGKCLVAVCDDSSVWMFEAIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8I9</accession>
    <name>A0AAD9D8I9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8I9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042223603" evidence="1">
        <location>
            <begin position="20"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="307" mass="33641" checksum="A31BA70966BA8DBE" modified="2024-05-29" version="1">MILRFSLLLLLCPARTILAFSPNSHGGICSSRHRLPILSSSSLSNFGLPSSDNQSGCNDILHQSQPFDKTYNQIKSTDQTFQGFISRWVAVSLAAAIMLSFSFTSFPLSCYAEDVVAADKDIIAEMGLKQPTEFRPQIRLTEDALNSVSTKSKARTPILQGLVYFPERARDTPDDTTSISTSTPSKEPLDYYSDILVLTAVSAKDPSGPILAGAKFPVSSVRFPFSFSMYEQNLLLKRAGVKEAWEDVQNTSDVIIKAYICPSDAVAFPCEDKEVKKYSEGVAKLITELPGLREGEVIRAPASLPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8U3</accession>
    <name>A0AAD9D8U3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Methyltransferase</fullName>
            <ecNumber evidence="8">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_011011</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8U3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016263">
        <property type="term" value="F:glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026050">
        <property type="entry name" value="C1GALT1/C1GALT1_chp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033">
        <property type="entry name" value="BETA1,3-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033:SF14">
        <property type="entry name" value="GLYCOPROTEIN-N-ACETYLGALACTOSAMINE 3-BETA-GALACTOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12847">
        <property type="entry name" value="Methyltransf_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="17"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1738342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="737" mass="83863" checksum="6CA15C6460F63F66" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D957</accession>
    <name>A0AAD9D957_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">OSTA/TMEM184 family transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_012145</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D957"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005178">
        <property type="entry name" value="Ostalpha/TMEM184C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23423">
        <property type="entry name" value="ORGANIC SOLUTE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03619">
        <property type="entry name" value="Solute_trans_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01417">
        <property type="entry name" value="Solute_trans_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="316"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="393"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="433"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="60"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1737278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="592" mass="66749" checksum="F42FC72370398A53" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D997</accession>
    <name>A0AAD9D997_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_011836</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D997"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="8"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1737550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="266" mass="29536" checksum="54F4F5DB327EAF13" modified="2024-05-29" version="1">MNTAASCCSVCGKKESPAQKLLQCSLCSSSKYLLCGKKCQRKDWRRHKKEECFVLRVEDGSPSDPCACGLCEGGDTEDEDAVSDFFNELHFIRGNNKAFKFINDDTSSSSNVMVNGVPTNLVQVTLSEEELDRIAYPFPMLVYKGHTMLDKTKTFYAPDGKAFTVRQLATAIAKAEKENKDKLEMMGMMGGGWYFEGLRRLEEPHTFAGYWGTNMISFRSGFNVVGMGFNPLTSRIAAMEHKVGEGGTPKECVQDQGSTMDIPFVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9M5</accession>
    <name>A0AAD9D9M5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">G8 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_009740</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9M5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055401">
        <property type="entry name" value="CEMIP_beta-hel_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052387">
        <property type="entry name" value="Fibrocystin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019316">
        <property type="entry name" value="G8_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46769:SF2">
        <property type="entry name" value="FIBROCYSTIN-L ISOFORM 2 PRECURSOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46769">
        <property type="entry name" value="POLYCYSTIC KIDNEY AND HEPATIC DISEASE 1 (AUTOSOMAL RECESSIVE)-LIKE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24606">
        <property type="entry name" value="CEMIP_beta-hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10162">
        <property type="entry name" value="G8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="G8" evidence="6">
        <location>
            <begin position="89"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="CEMIP beta-helix" evidence="7">
        <location>
            <begin position="442"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1739197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="561" mass="59479" checksum="A3E9EC02D0811E4F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DA59</accession>
    <name>A0AAD9DA59_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Clathrin heavy chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_010584</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <location evidence="2">Coated pit</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the clathrin heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DA59"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030132">
        <property type="term" value="C:clathrin coat of coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030130">
        <property type="term" value="C:clathrin coat of trans-Golgi network vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071439">
        <property type="term" value="C:clathrin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032051">
        <property type="term" value="F:clathrin light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006898">
        <property type="term" value="P:receptor-mediated endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000001">
        <property type="entry name" value="Clathrin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000002">
        <property type="entry name" value="Clathrin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055358">
        <property type="entry name" value="CHCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012331">
        <property type="entry name" value="Clathrin_H-chain_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015348">
        <property type="entry name" value="Clathrin_H-chain_linker_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016341">
        <property type="entry name" value="Clathrin_heavy_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10292:SF1">
        <property type="entry name" value="CLATHRIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10292">
        <property type="entry name" value="CLATHRIN HEAVY CHAIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00637">
        <property type="entry name" value="Clathrin"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09268">
        <property type="entry name" value="Clathrin-link"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13838">
        <property type="entry name" value="Clathrin_H_link"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002290">
        <property type="entry name" value="Clathrin_H_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00299">
        <property type="entry name" value="CLH"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0168">Coated pit</keyword>
    <keyword evidence="7" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clathrin heavy chain linker core motif" evidence="9">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="8">
        <location>
            <begin position="236"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="8">
        <location>
            <begin position="385"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="8">
        <location>
            <begin position="556"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="8">
        <location>
            <begin position="720"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="8">
        <location>
            <begin position="866"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="8">
        <location>
            <begin position="1014"/>
            <end position="1159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1738554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1273" mass="142592" checksum="226F9C4EE852E4F1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAG7</accession>
    <name>A0AAD9DAG7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009226</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAG7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042127986" evidence="2">
        <location>
            <begin position="24"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="147"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="197"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="216" mass="22877" checksum="345419E70D410304" modified="2024-05-29" version="1">MKLSVAVALITLLSGAHTGAASARPARIRSSQNQHESSQQTEDMDIYLGLAPDEDNHRKLQSVSISMPMSMPPEPVNPIIEPVPENPIEPLPENPIEPVPENPPEPVPENPIEPVPENPIEPTPGDETTGSAEPEPPVEPDNPFFAKSVKTSKASTTSSKSKTLKDHPMAKVAKSVNDAKAEKLSVAKSTKAKSAKSKASGSGSAKAGKLFKESMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAW2</accession>
    <name>A0AAD9DAW2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">4-carboxymuconolactone decarboxylase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008702</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAW2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34846">
        <property type="entry name" value="4-CARBOXYMUCONOLACTONE DECARBOXYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G11590)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34846:SF5">
        <property type="entry name" value="CARBOXYMUCONOLACTONE DECARBOXYLASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="307" mass="34252" checksum="0C56E06E32D91085" modified="2024-05-29" version="1" fragment="single">TVCVRYVGIPLLKGANDLSAGSRQPQHLHHVVISHYPGFVFTKASYKHQTRLEGQMIANLLPRLKYNHNRYHHFCRRKMSENTQYIPTSTAFQPRYTGPSPENMTPEQTALRQSILESRPRTGLSGPFGPWLAVPSIARPSQELGRTVRYETSLSMRESELVILLTGAKFKSEAEFDIHAGEAMRAGVGLDVIKSIPRGALLSQEGRKDGKDNNAEFSLENVKKHMLPLLEKENAYEGKGDLLRDIPIVLFTAELLETNAVSDETYAKTKRLLGGDDSVLVEITAIVGYYAYVAYTLNVFRIASSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DB93</accession>
    <name>A0AAD9DB93_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009378</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DB93"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="509"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="557" mass="61635" checksum="7A4E76C3ED8956D7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBE4</accession>
    <name>A0AAD9DBE4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009543</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBE4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="297" mass="33407" checksum="2ADB84CF43A5BAFD" modified="2024-05-29" version="1">MDSAPTIIKLIHSLAYSSLPSEDVLFQIVKTVVPIAKIMSLLTIVSVWSASKSMPFSRNIYKYAFMGAIAKLVHFFLPYGDTDMGSKLESLFEDLSFVLPLMGVIVTTGLDFLWALSSSIDSDILFRRNISEYDFVVKFERIQPIVTIFLAFARYAPNTNINVEGLVFAHLCFAVWLVTSYGFIWFCLWKVAGASETKRFQDAYHKSFAITAFVSSQILLYLLVLFPCVYDAELCRKFILVTHLLETLAIVALVAFFAFFKAPPADLQANKMNWTQMSGVMKAKAKLKAKKASNKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DC71</accession>
    <name>A0AAD9DC71_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009320</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DC71"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="220" mass="23899" checksum="8F4A73A61CB6831E" modified="2024-05-29" version="1">MFEKCRGIEYDKHHSQAAFALETEYNKYNYKQQQLVNSSATKEETKDNDPIQKSHDYGTTASCVQYICGDLGDETFEGASVVYSNAVVFDSPLCSTLGRILDDATLQPNAFVVTATKQFALPSFELVDMLQLPCNGGQLFTFYVNQKRTSSGSDSTMSGSERGAVPAVSDSEYMRLLRSTHTTSEREGSSSSSNMMEQLVAISLQDGGLAGLAFLAALGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DD04</accession>
    <name>A0AAD9DD04_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DD04"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="173" mass="19106" checksum="801974D76D299818" modified="2024-05-29" version="1">MWEKKKVSSKKNIYPQSSLQNVAMTALPRRDIGGLAHSALAADAPRKIFIRDGGTSSSSLRSRAYRKGKRNEEERQAASENFHDAFGVEDSNPNFDGDGFALSGLDPTQPSSQHHGKYLKWGDELLEEHERNAYPACCPPLPPNIPLNIKMAITSKLGDILPSDDKLVAKLYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DD64</accession>
    <name>A0AAD9DD64_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nuclear speckle splicing regulatory protein 1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_005897</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NSRP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DD64"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000381">
        <property type="term" value="P:regulation of alternative mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018612">
        <property type="entry name" value="NSRP1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30060:SF0">
        <property type="entry name" value="COILED-COIL PROTEIN (DUF2040)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30060">
        <property type="entry name" value="INNER MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09745">
        <property type="entry name" value="NSRP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nuclear speckle splicing regulatory protein 1 N-terminal" evidence="4">
        <location>
            <begin position="68"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="163"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="94"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="205"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1743276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="319" mass="35824" checksum="A1783E46000F9E89" modified="2024-05-29" version="1">MSSSGKGSLSYGLNNKKRKKGGLTGFADDSSSSDDDAAAGKTGPLSGRSAMNREIAAEQAALRKRAEAAMASSSKMDSAVFDYDGEYDSFASGNKKETKTQQREPAGKGQSRYVSNLLQSAQRRSQEQEIIYERKVVKEQAEEKEFEGKEKFITSAYKKKLAEREAWAKEEEERAKREAEDDVTNKKGGSFLYGFSRNVLMGVNDNKKDDKSTSNVAHKDDALDTASGRKEESTYTDQQSYQRRDFSRQPENPLPPRQRGDTNNFSRNPQPSEEIENTNTKAADETKQPLTRSQILAERAVKIREARERYFKRHGLPNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEG5</accession>
    <name>A0AAD9DEG5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mitochondrial-processing peptidase</fullName>
            <ecNumber evidence="4">3.4.24.64</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_005780</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.64" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEG5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050361">
        <property type="entry name" value="MPP/UQCRC_Complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018908">
        <property type="entry name" value="TMEM234"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851">
        <property type="entry name" value="METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851:SF49">
        <property type="entry name" value="MITOCHONDRIAL-PROCESSING PEPTIDASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10639">
        <property type="entry name" value="TMEM234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="3">
        <location>
            <begin position="195"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1743159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="564" mass="57912" checksum="7B4F155A68920710" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DF20</accession>
    <name>A0AAD9DF20_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004143</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DF20"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="446"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="493"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="566"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="218"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="446"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="497"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="524"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="577"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="623"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="639"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="678"/>
            <end position="692"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="692" mass="78205" checksum="4C6A51390A48CA61" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DF70</accession>
    <name>A0AAD9DF70_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">50S ribosomal protein L35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_006064</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DF70"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00514">
        <property type="entry name" value="Ribosomal_bL35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001706">
        <property type="entry name" value="Ribosomal_bL35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021137">
        <property type="entry name" value="Ribosomal_bL35-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037229">
        <property type="entry name" value="Ribosomal_bL35_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33343">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN BL35M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33343:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL35M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01632">
        <property type="entry name" value="Ribosomal_L35p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143034">
        <property type="entry name" value="L35p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="67"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1743443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="110" mass="12324" checksum="B62CAFA1E3C7B747" modified="2024-05-29" version="1">MFTSLLRSTSSLISRGTSWNISMFKTHIMPSPSLLTNITERGLAGKALLRTNKSAAKRFRVRGNARIKRNKAGRSHNTGHKGRKRINNLAASAPINGKKIEDRMRRLIRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFE1</accession>
    <name>A0AAD9DFE1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005220</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFE1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="39"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="206" mass="22992" checksum="FA7FF7906880276A" modified="2024-05-29" version="1">MPSSKASKNKNNSSTRLPPKTQQRKQAGKPAKVNVKKILMEETETKERLKDTLESLTERLIAVLDSGGVPKERTKEIQRQLVLVFDNSDTSASLTEQLQSIIVVLSDATKVVEKSWSYCHCYPSMDVPTLSSILDELQTVLCESAFLANKPLQRKLVNLQADPKADAAVLNELESVSKQVSDLITSTKATLYMTHVRMVVFNQEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFG1</accession>
    <name>A0AAD9DFG1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Methylenetetrahydrofolate reductase</fullName>
            <ecNumber evidence="7">1.5.1.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_005447</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the methylenetetrahydrofolate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.20" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFG1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004489">
        <property type="term" value="F:methylenetetrahydrofolate reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00537">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004621">
        <property type="entry name" value="Fadh2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003171">
        <property type="entry name" value="Mehydrof_redctse-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00677">
        <property type="entry name" value="fadh2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45754">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45754:SF3">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02219">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="FAD-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1743850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="377" mass="41681" checksum="9F5787A1DF3B845C" modified="2024-05-29" version="1">MCSATATNAVDPKIIDLLNKDPEGLAHVSLEYFPPRTEQGVKNLHARMERMLTNTKCLYTDMTWGAGGSTAELSLELALHAQKTGHVSNLHLTCTNMEKDGDPIKGVHDALQAAFDGGIRNIVALRGDPQEGENEWTATKGGFTCALDLVKYIRKEFGDDFGVSVAGYPEGHPNRISELTEDEVKSMSESELSRCCTHDGIAYVCKDDDYKKEMDYLKEKVDAGADFIITQMFFDAEVFKIFVEDCRTWGINCPVVPGLMCINAYPGFKKMTKFCKTRVPKALEEKMDSMKDDADAIKKFGVEYGAEVCRTLLDSGVKILHFYTLNLEKVVYGITDELGITSGLTEQSNESDAKIWLLLVVPGLGQVTQLSAVLVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG49</accession>
    <name>A0AAD9DG49_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">YjbQ family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_005148</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DG49"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.460">
        <property type="entry name" value="YjbQ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004345">
        <property type="entry name" value="TB2_DP1_HVA22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001602">
        <property type="entry name" value="UPF0047_YjbQ-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035917">
        <property type="entry name" value="YjbQ-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300">
        <property type="entry name" value="HVA22-LIKE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300:SF161">
        <property type="entry name" value="RECEPTOR EXPRESSION-ENHANCING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03134">
        <property type="entry name" value="TB2_DP1_HVA22"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01894">
        <property type="entry name" value="YjbQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111038">
        <property type="entry name" value="YjbQ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1744615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="594" mass="66380" checksum="E5AB463D9F19D094" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG52</accession>
    <name>A0AAD9DG52_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SET domain-containing protein</fullName>
            <ecNumber evidence="3">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003078</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DG52"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF155">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="768" mass="86915" checksum="702CB720DD868456" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGL7</accession>
    <name>A0AAD9DGL7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_004189</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36489:SF2">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36489">
        <property type="entry name" value="PROTEIN-COUPLED RECEPTOR GPR1, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042095838" description="PDZ domain-containing protein" evidence="3">
        <location>
            <begin position="18"/>
            <end position="1660"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1277"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="525"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="901"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="947"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1069"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1344"/>
            <end position="1373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1415"/>
            <end position="1452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1547"/>
            <end position="1568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="146"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="232"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="273"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="337"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="487"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="569"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="696"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="718"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="731"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="784"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="826"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="907"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="957"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="998"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1011"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1027"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1069"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1352"/>
            <end position="1373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1432"/>
            <end position="1445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1744898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1660" mass="169769" checksum="A3D1CF6D8B0470A7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHC3</accession>
    <name>A0AAD9DHC3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Malonate-CoA ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_001799</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHC3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031956">
        <property type="term" value="F:medium-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05941">
        <property type="entry name" value="MCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF8">
        <property type="entry name" value="ACYL-COA SYNTHETASE FAMILY MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="2">
        <location>
            <begin position="33"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="2">
        <location>
            <begin position="170"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="3">
        <location>
            <begin position="428"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1747836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="515" mass="57604" checksum="C138A568751F259F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHI2</accession>
    <name>A0AAD9DHI2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_001350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHI2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="61" mass="6756" checksum="28843CBF40728EB0" modified="2024-05-29" version="1">MFKLLHGGGGSGAGRRRDVFKAFEKKLQEDRAAKGQPHEINTDSGGFFSRLRGSKYMIPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHL2</accession>
    <name>A0AAD9DHL2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Leucine-rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002752</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHL2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="327" mass="36917" checksum="02F028A2ACD0BB32" modified="2024-05-29" version="1">MMNDIDNQPVGGIYVYRGGRAPNNITHAVIDKSVKVIDEGAFRNNPFLHTVEMHDGIDRVREEAFHLCHSLLYVNLRRVQILDSLAFANSGLTHVDGDDLEIIRDNAFQGCENLKKIAFSSLRVIEPCAFEDTDLRELNLPEVEQIGVCAFVSNSHLRRIAIPLKANLFFIDPLADDSEIVDTAFSGCHINHVDLIGSIHETVSSLHMESWRNDMTHEINQINKTLENSYSSKQNTAVIRWWLQSVCSRIEHYKTEHLKVLKAATVLLELALWKAKLSEKDEDESSDCAKVKRIKIDVEDARSEARGSCGAGMNIIIKNVLPFLELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHR5</accession>
    <name>A0AAD9DHR5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_001635</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHR5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="134" mass="13720" checksum="FB599AD1447C45D4" modified="2024-05-29" version="1">MASPIPQTPSVAVSVSPAVAGSAAPSAATSAIIDLDSIPGQIGHAILRASDGTILRPPTGSLSEQDLMIVYRMMLEIGTVLEGGTGGKEDDNNTSNEVEEGLQRVTVGFKDVSYAVTLGGSDGCLYIVKKKSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIR7</accession>
    <name>A0AAD9DIR7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Arginine-tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_000691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.19" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIR7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1748752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="111" mass="13423" checksum="D40E879747A93B2D" modified="2024-05-29" version="1">MDILIVMVPRCLCLSESQMVDSIMQLLTWLPFAIAFRWRHPMAEKRLTEFCTSLMRANRSILRWYSLLQRRRVCYRFCVVRTCSVRSCTGRRWQEICYPLWRYCEAEGSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJ04</accession>
    <name>A0AAD9DJ04_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Membrane magnesium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_001261</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJ04"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042212410" description="Membrane magnesium transporter" evidence="3">
        <location>
            <begin position="25"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1747298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="191" mass="20256" checksum="6B0EA48906693A91" modified="2024-05-29" version="1">MKVCLLHAGIASSLLIAFVVESAASNIPPLRHLQTYHNGHNRALSSSAESLNTTVRITPSAAPSMHPSVQISLSSSAPSALPESKLDPTDNSLSMSAATASHSSTMSGSSTIPDKSQQQQEESGIFGMSLFQTCAAVILVATVVGLFGHFGMKLLPYNRHREDNSRNDVQLEDSLASFRTLPRTSLSHVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJ10</accession>
    <name>A0AAD9DJ10_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zinc finger PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001907</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJ10"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="462"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="466"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="601" mass="67808" checksum="74EA3746350930AA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJ34</accession>
    <name>A0AAD9DJ34_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Metalloprotease (Family M6)</fullName>
            <ecNumber evidence="8">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_001518</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJ34"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055372">
        <property type="entry name" value="CBM96"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008757">
        <property type="entry name" value="Peptidase_M6-like_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033764">
        <property type="entry name" value="Sdr_B"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF033679">
        <property type="entry name" value="DNRLRE_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41775:SF1">
        <property type="entry name" value="PEPTIDASE M6-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41775">
        <property type="entry name" value="SECRETED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24517">
        <property type="entry name" value="CBM96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05547">
        <property type="entry name" value="Peptidase_M6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17210">
        <property type="entry name" value="SdrD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49478">
        <property type="entry name" value="Cna protein B-type domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Peptidase M6-like" evidence="5">
        <location>
            <begin position="28"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="SD-repeat containing protein B" evidence="6">
        <location>
            <begin position="628"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate-binding module family 96" evidence="7">
        <location>
            <begin position="797"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="356"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="507"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="761"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="359"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="392"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="507"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1747555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="949" mass="103191" checksum="152B5EF395920AFE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DL21</accession>
    <name>A0AAD9DL21_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PPIase cyclophilin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001232</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DL21"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.780">
        <property type="entry name" value="von Hippel-Lindau disease tumour suppressor, beta domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037140">
        <property type="entry name" value="VHL_beta_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042265967" description="PPIase cyclophilin-type domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="2">
        <location>
            <begin position="141"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1749293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="311" mass="34983" checksum="6BF74CE086E19580" modified="2024-05-29" version="1">MAGAFLLCSALFLCAIAARTGTVANEQPQQQRRQVTVTFVNELPNAQIDLYWENHETGGRKFEGTIDPRGGFLRVDTYDGHEFSYEIESDGERHYFQPKGFAVLLGSTHCIQVRCDVTTYSRKSSDTFNILVKPYWSQRGASRFLELVRSGYYDGVALNRVVPGFLTQFGIAADPTVRNHWGKLAVVDDLPFNDIPFQPGYLSFAGSGIDSRTTEIFIVMPGVGQEQLDYFGENSWETPFGLLEGNVEESALTKIYSGYGDMPPWGKGPESSRIYDEDGYTTYLPNAFPLLDYIERCYVVDEVDIDIEEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRM8</accession>
    <name>A0AAD8XRM8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Circumsporozoite protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_016776</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Essential sporozoite protein. In the mosquito vector, required for sporozoite development in the oocyst, migration through the vector hemolymph and entry into the vector salivary glands. In the vertebrate host, required for sporozoite migration through the host dermis and infection of host hepatocytes. Binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes.</text>
    </comment>
    <comment type="function">
        <text evidence="5">In the vertebrate host, binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes and is required for sporozoite invasion of the host hepatocytes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the plasmodium circumsporozoite protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000064">
        <property type="protein sequence ID" value="KAK1732564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRM8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051860">
        <property type="entry name" value="Plasmodium_CSP_Invasion"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44826">
        <property type="entry name" value="SPORE COAT PROTEIN SP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44826:SF3">
        <property type="entry name" value="SPORE COAT PROTEIN SP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49478">
        <property type="entry name" value="Cna protein B-type domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117074">
        <property type="entry name" value="Hypothetical protein PA1324"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0748">Sporozoite</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="90"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="623"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="90"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="128"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="194"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="218"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="628"/>
            <end position="637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00033726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00045806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1732564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="703" mass="77080" checksum="169545F7DD742EE8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSB3</accession>
    <name>A0AAD8XSB3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sulfotransferase family protein</fullName>
            <ecNumber evidence="4">2.8.2.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_016462</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfotransferase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.2.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSB3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11783">
        <property type="entry name" value="SULFOTRANSFERASE SULT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sulfotransferase" evidence="3">
        <location>
            <begin position="69"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1732924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="377" mass="42707" checksum="DC25C21C49710F45" modified="2024-05-29" version="1">MALIKNVGKAVLGLAVLIGSIGKFAPHLFFDLPFPFSVILWVTTGNSMPMYFMPDAWKEDEIDSWMKDGDLVVATGAKSGTTFMLYCTHQIRTKGTDLDDELFPDVSLATPWMDLKQSRTGSWAEQKDRYNDTVLSNGRKLKEYWDNPAFPFRIFKSHYAPPELPVRKKGGKQIKYLAMARNGLDVAASMTNFYSSHTDEFRKVWGGFPPDISGEDHAADEPPAAVKDMLPTGPMAEIYFGYVKKWWAFRNDPNVLYMHYADVRKDLKGHVSKIAKFLEVDLNQNELDVVTKRCGIEHMKSLPDKFGYKMPLNLDKGLWDSEKDTIVKTGAMVNTGEVGKGKAKFHPKVVEQWRKAEEDMLGDDPDLLNWARNGGKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSF7</accession>
    <name>A0AAD8XSF7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">L-fucose kinase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_016500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000057">
        <property type="protein sequence ID" value="KAK1732788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050201">
        <property type="term" value="F:fucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070569">
        <property type="term" value="F:uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042352">
        <property type="term" value="P:GDP-L-fucose salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052203">
        <property type="entry name" value="GHMP_Kinase-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002618">
        <property type="entry name" value="UDPGP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32463">
        <property type="entry name" value="L-FUCOSE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32463:SF0">
        <property type="entry name" value="L-FUCOSE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01704">
        <property type="entry name" value="UDPGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="14"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="139"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="266"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="14"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="311"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1732788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1333" mass="146932" checksum="B9D5B41DA73C58D0" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTP4</accession>
    <name>A0AAD8XTP4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000048">
        <property type="protein sequence ID" value="KAK1733532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTP4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="1">
        <location>
            <begin position="25"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="375" mass="42167" checksum="7A9A0BC9D258590A" modified="2024-05-29" version="1">MMVPPTKAAAAAAAAAATAATAATKIKTLNVAPGKIGLTLKVNLAGATVTSIESSSGCNGKIDVGDVIVAIDGRKLQKVEDCHYNANKARQFTIVLKKKEAVAATTCNEYSLLPLKSQVPPHVIEETLSIFRKKYAKEIAKLKIGAKPNVEINHIFNETQEVTKESKRYQLAVDRRTTLYKSDLVSKHLIPIITKYCQDHYDGTFEIHKTLLLMSDAFCPEQKEHTDGIDNANDFIVALFTLQDNTYFRIRDRLNRELKELVMPQNTLLFFHSLKLHAGGRNPTNEINFRLHFRIGRKHDRTKSISMAEQIRFPETCCYGCGRTYTIYSSRKNHEYTCSLNKEGDAHRAAENDQVRELRAGRKRVRLEAQEMKAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XU31</accession>
    <name>A0AAD8XU31_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015925</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000050">
        <property type="protein sequence ID" value="KAK1733366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XU31"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042222668" evidence="2">
        <location>
            <begin position="18"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="498"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="550" mass="59776" checksum="61F35E959A422839" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUX3</accession>
    <name>A0AAD8XUX3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015467</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUX3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="144" mass="16731" checksum="08AA123800DC8C63" modified="2024-05-29" version="1">MDDALKPKWGDVDFDDRFARNLFHCIDDGGDVQVEIISSDFASEKDYESLLKHSDDQAHFKLTEVADKFVVSVKWIEREKNEKKVVQFQISEDLFDMIKGFHCVQSDKRANIDMDALMREMKREAYLKDYGIDIDVLCSPPLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV54</accession>
    <name>A0AAD8XV54_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015248</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1733990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV54"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63825">
        <property type="entry name" value="YWTD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="226" mass="24990" checksum="3AC1DE15DC982712" modified="2024-05-29" version="1">MQTLLGGTGGQYEAVAVDDRGINPVFFVTEDKWNGALRRVESSCSGWGALHGTRNGCTLDTKYLRLRPNQDPPSFTWVTDKGVGKTSAANHFPNSEGIAFHNGKLSFVSKTKKEMFTLDLDEETYEEERTGLKFRGKGSFKGQPDQTLDDLDSNYMYFTEEDGIGVGVYARHDKDGCYSTLFEDNGARKGDETVGTATSPDGTRLYVGFQGSGELFVVERKDKGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XX92</accession>
    <name>A0AAD8XX92_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyl-CoA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_013742</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ACBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XX92"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000582">
        <property type="entry name" value="Acyl-CoA-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035984">
        <property type="entry name" value="Acyl-CoA-binding_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23310:SF62">
        <property type="entry name" value="ACYL-COA BINDING PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23310">
        <property type="entry name" value="ACYL-COA-BINDING PROTEIN, ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00887">
        <property type="entry name" value="ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00689">
        <property type="entry name" value="ACOABINDINGP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47027">
        <property type="entry name" value="Acyl-CoA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51228">
        <property type="entry name" value="ACB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACB" evidence="3">
        <location>
            <begin position="4"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1735579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="98" mass="10928" checksum="F9793CDB30E1A202" modified="2024-05-29" version="1">MTVSAENFEKIARLVGDPNTPAARPSTRAEKLQLYGLYKRATVESDQRPQRPGMFNIDGRMKWDAWAAEDGKSKEEAMQAYVDLAKELVGKAVEDVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXQ8</accession>
    <name>A0AAD8XXQ8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">mRNA splicing factor Cwf18-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013984</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXQ8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013169">
        <property type="entry name" value="mRNA_splic_Cwf18-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31551:SF1">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31551">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08315">
        <property type="entry name" value="cwf18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="141"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="32"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="182" mass="19947" checksum="25FAD2E3449FA2EF" modified="2024-05-29" version="1">MSDDRKARLAALAARAGRNQPIAATGNSSQETDNKDESQKMDVDAKPAISFRNYVPKDASLDKAVTASANDTDETQPAAPKRQKTTTSNSQNSEEPKSALELALAKTDRESREAAGHNVGEAGGWSKVVPISTKKVNWDLKRGIEQKMERLERRTQKAIVELLRERLEQEAREGGGDESDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXS9</accession>
    <name>A0AAD8XXS9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_013648</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXS9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1735485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="137" mass="15304" checksum="EB869F0FAE63864A" modified="2024-05-29" version="1">MEEKIKKLDEATTASQLAMLDAESKLAAASDALEAAKSKLKQLSPEAQQNIEFNDTELPDLISAKMLAESECENARKRYETNEKYLMMFREKLSKSSWSDNTVEWRKGLQAKTAFYSYSEILCVQAVPDAGANTGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXW1</accession>
    <name>A0AAD8XXW1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">2OG-Fe(II) oxygenase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_013615</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXW1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043527">
        <property type="term" value="C:tRNA methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016423">
        <property type="term" value="F:tRNA (guanine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11715">
        <property type="entry name" value="THUMP_AdoMetMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2130.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000241">
        <property type="entry name" value="RlmKL-like_Mtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053943">
        <property type="entry name" value="RlmKL-like_Mtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14911">
        <property type="entry name" value="THUMP DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14911:SF13">
        <property type="entry name" value="TRNA (GUANINE(6)-N2)-METHYLTRANSFERASE THUMP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01170">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00507">
        <property type="entry name" value="N12N6MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143437">
        <property type="entry name" value="THUMP domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01261">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="7">
        <location>
            <begin position="119"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="56"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1735909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="738" mass="83244" checksum="9F6A363530D4A398" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XY39</accession>
    <name>A0AAD8XY39_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA excision repair protein ERCC-6-like protein</fullName>
            <ecNumber evidence="2">3.6.4.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XY39"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050496">
        <property type="entry name" value="SNF2_RAD54_helicase_repair"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629:SF7">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629">
        <property type="entry name" value="SNF2/RAD54 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="38"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="212" mass="23875" checksum="535B60159E022C4F" modified="2024-05-29" version="1">MTIPIQRRRQNGPRLNCLFLCTTNSTNINELVFNGWQVCITMKSRGGLLADDMGLGKTMQVLTYLGSLMRAETICNAIIICPKSVVRSWEREANLNLKNICVPRATVTAVTSDMGKAKRKRVFEDAFCAPSKRPQLVITTYGLVSNHITDLTNISNTYEESRWCYVVLDEGHQIKNSSTKMSRDVRILASRSPHTRRLLMTGTPMQVSTNVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYK3</accession>
    <name>A0AAD8XYK3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_013553</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYK3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36971:SF1">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36971">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1735847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="330" mass="36606" checksum="F75443C73A3D2C10" modified="2024-05-29" version="1">MSGDGATIILSFQPNHFKLFLSKKSSLLVINAKCINGAKNRIKSKNAALVHIRHPKDVLSKMASSLLLQSADSLQDMKKGCKVEADTTKKIVVRARANIERNRKGDRLIECIDVLCVQEDGDATYLPVDNDDEEYCEYITGKTYENPISLKVERSKIFAEWIIDTYGKELLCRGTGVLDVAGGNGETCRHLVAKGIPVTLLDPNPRCGSNPGFTIIPHPLNCDGSDLTSRNDNIGHIVRSCSFICGLHPDQATEPIVSLAERLNVKFAILPCCVMPSLFPHRVQRKHGDPVRSYSAFCQYLLDMAPEKEEFLVDHLPFVGRNKVIYRAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYS7</accession>
    <name>A0AAD8XYS7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UTP-monosaccharide-1-phosphate uridylyltransferase</fullName>
            <ecNumber evidence="6">2.7.7.64</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_013344</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a monosaccharide 1-phosphate + UTP + H(+) = a UDP-monosaccharide + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13205"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:140358"/>
            <dbReference type="ChEBI" id="CHEBI:140359"/>
            <dbReference type="EC" id="2.7.7.64"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the USP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.64" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYS7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003977">
        <property type="term" value="F:UDP-N-acetylglucosamine diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051748">
        <property type="term" value="F:UTP-monosaccharide-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.10.30:FF:000001">
        <property type="entry name" value="UDP-sugar pyrophosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000091">
        <property type="entry name" value="UDP-sugar pyrophosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039741">
        <property type="entry name" value="UDP-sugar_pyrophosphorylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002618">
        <property type="entry name" value="UDPGP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11952">
        <property type="entry name" value="UDP- GLUCOSE PYROPHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11952:SF9">
        <property type="entry name" value="UDP-SUGAR PYROPHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01704">
        <property type="entry name" value="UDPGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042232565" description="UTP-monosaccharide-1-phosphate uridylyltransferase" evidence="8">
        <location>
            <begin position="24"/>
            <end position="710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1736208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="710" mass="77233" checksum="0904D8886E4C4610" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZT6</accession>
    <name>A0AAD8XZT6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">inorganic diphosphatase</fullName>
            <ecNumber evidence="3">3.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_012921</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZT6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00412">
        <property type="entry name" value="pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.80.10">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008162">
        <property type="entry name" value="Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036649">
        <property type="entry name" value="Pyrophosphatase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10286">
        <property type="entry name" value="INORGANIC PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00719">
        <property type="entry name" value="Pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50324">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00387">
        <property type="entry name" value="PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1736321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="270" mass="29663" checksum="0CEAFABAD64B33BC" modified="2024-05-29" version="1">MTASLLFRQSSSFLLKQSTTKKTTTMKFTAAPLALLALATPITTSAWSTAAVRSVRAVPATILHGYTTATTGESATESFRLSFAEGDDTISPWHDIPLKGNADGTYNAVIEIPKMTKAKMEVATKEPNNPIAQDMKKGKLLLRDDDPIDVVEIGSKAIAMGSVTEVKPLGVIAMIDDGELDWKVIAIATDDELAKEYNDIDDVPDAVKDGIREWFRWYKTPDDKPLNGFGFDEKWLDAKNANEVIEETHDAWKKLRSGEIEAGKLWTGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZU2</accession>
    <name>A0AAD8XZU2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">S1 motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012691</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZU2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050437">
        <property type="entry name" value="Ribos_protein_bS1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10724">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="168"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="239" mass="26710" checksum="8B2C54818CD7BE42" modified="2024-05-29" version="1">MAASSLYSTAIAASFICSTYVSSTSIRSATDGDTIDSMFGPRLDGEDDEVLYSDDDDSDDWGAPSLVTPAEPKKEKAMSRWGSLNPKIKAPADLNPGETVPGRMNSWTPSKVFGTGDDVEVRIVRMDPGAKKLQLTMLPEEVLHEENVLNKHMIDEDEDDRIQLDEIEVDDELWGEIRRVTDYGAYIELVKGAHPKEFMRVGDRVRVWVLDVDSTQQRIKLTANRPSGLPGPRREVKWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZW9</accession>
    <name>A0AAD8XZW9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoglycerate mutase family protein</fullName>
            <ecNumber evidence="1">5.4.2.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.-" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZW9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF1">
        <property type="entry name" value="HISTIDINE PHOSPHATASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1736548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="239" mass="27223" checksum="77C8C5FC75CA99DB" modified="2024-05-29" version="1">MQQQQMKTVYFIRHGVARHNVPDPNTGQMPNLHDERYTDPSLIQEGEMQACELGAKLRQMGLVSDVMSGSSEAMDTGCNTKQPIDLVVCSPLTRCIQTASHIFPNFSSICCHGGVREAFGMHYPDRRSPLSQITAKFPHLTYHHPSLSSEDDIDWQPHIRETRDDVVRRIDNFLAWLTQQPQQSIGIVSHGVWIECALLKYCPQVLEFGKKRVYNCEVYKAHLAYDENKLVLNNVEQIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0L2</accession>
    <name>A0AAD8Y0L2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012662</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0L2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43036:SF2">
        <property type="entry name" value="OS04G0481300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43036">
        <property type="entry name" value="OSJNBB0011N17.9 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="1">
        <location>
            <begin position="22"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="127" mass="14650" checksum="889F4165490A8291" modified="2024-05-29" version="1">MNEKELKANEQLTNHFVQDLNINPDLSQFEDDSFDVICNVVSVDYLTKPLEIFQEMHRILRPGGVSLMTFSNRLFATKAVAMWLQADDIGRLTIVASYYNYSADWKSIEALDIKEKQPLPERPPTQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1T0</accession>
    <name>A0AAD8Y1T0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_011914</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1T0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="3"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="41"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1737628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="231" mass="26016" checksum="6FB618933F07F94B" modified="2024-05-29" version="1">MPPSKTAAQSVFRQIDKNGDGKISREEYKMALKILDIPSSMTTVVTDAVFAKYDADSDGGIDEKEFVKYFDSTSNVEMHSRIDRAVFEKSYSFFWAMYFIVIGIKFVSDPFEQTDQTFAGISSNDGPGFRHAAAHLFTIIGLTWICIGVLAIAQRVLKLTPVVTQAAIAFFWFLLTLYENVLGQLLAPPDLRLRPHLSLSSRLSLHSLECGVHYLERLRLRRTRLGVLDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1Z9</accession>
    <name>A0AAD8Y1Z9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1Z9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="343" mass="39431" checksum="930C435336C6123B" modified="2024-05-29" version="1" fragment="single">ETAKKLLGTARVACRFDADEFTSIVQSTFAIAENPVQYQSEGVSEPLQIKATIMSYNIKLPSNMCKEAVNTPTPVMKDPHDRSGHTETTTSFDDDDFPITKETFHASRLLRKDSIAVQKLHGPNDCEDHAKDPHLQDLLIPHHVVHMKRLDEDEPQLTAATTETDAESVSEESDADAAVTTPRRSCLRPETESYYDRPKTEKSKRKIHFGQVCVRDYDMILGDNPSVGYGPPVTIDWDYVEFNPIQMDEYEFHRPPRRSLREMGLNYYRRKHILALAGHTEEEFKVVKKEIKKWKTNRYLTRALVSSSIPFAKIEDSVESAVRKCRRLVKDDHWKSEKHLFVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2B5</accession>
    <name>A0AAD8Y2B5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ysc84 actin-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_010902</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2B5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1738233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="170" mass="17910" checksum="14B26D2725062584" modified="2024-05-29" version="1">MDTFKKQEILKPYFENSYGCAAFSSVAKGGIFFVGGAYGKGSVYKLPEEEVVGTVELIQASGGFVLGGEVYAEIIFFQTEADFTRFTEGNFEFGADAKVVALTASASTKATTMGNQGIQVGMTADGTQVGGANKDAAPEYTKGMKVFTVSLGGLMYQATISGQKFNVSMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3C6</accession>
    <name>A0AAD8Y3C6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010964</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3C6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09272">
        <property type="entry name" value="RNase_HI_RT_Ty1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11439">
        <property type="entry name" value="GAG-POL-RELATED RETROTRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11439:SF483">
        <property type="entry name" value="PEPTIDE SYNTHASE GLIP-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="429" mass="48730" checksum="A9086863D9342F23" modified="2024-05-29" version="1">MQAKCRQEQRQSVTSALGGFYREAYEEAFQYSPVIFDWSPTFNHYEWWSPRAEETYTSESYVNPTSDFYIEPEFIDGELAYEVPPLNDEWLTEQEAREKESRLQDQLLRDKQRKARYEAKFCPATPTADSNTTVKFNDAIKAPPTTNDDVYADDIPPDLASEAEGDDGDEDADIANEGDDGDEDADIANEGDERVVDIPGNGDTRVWNTRRRHTTNWKNRYGGDYAKRSHELALLRIGKYLKATRTKGIVIKPTGGLLNINAYPDADFAGLYGHENDTDSACVKSRTGFVILAANCPISWKSTLQTKTALSTMEAEISALAHCMKELVGIMDLAKLFSEYYGLEEVKTKVNITIHEDNSSALELANTIPPEYTSRSKFYHIETIWFREQIVTRGIEVVKIETTEQLGDIFTKGLTKEVFEYLRKKLCGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4M1</accession>
    <name>A0AAD8Y4M1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_010295</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4M1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023779">
        <property type="entry name" value="Chromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051219">
        <property type="entry name" value="Heterochromatin_chromo-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22812">
        <property type="entry name" value="CHROMOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00598">
        <property type="entry name" value="CHROMO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="4">
        <location>
            <begin position="412"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="593"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="615"/>
            <end position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1738979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="956" mass="107524" checksum="77212B72FF7A8A3F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y587</accession>
    <name>A0AAD8Y587_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009582</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y587"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="127" mass="14714" checksum="6F24264C78B0DAFE" modified="2024-05-29" version="1">MQEQQYHSQDVHQNCLGDGDTQQKIPLPIDIIEFDSGETTAPGETKTARHNHRQPHQLLDAARQDRAQKDDHQHGDGESCRVHKSERHRDDNNKPERREKKDDEDKNSSSDESIQTNNVRRGFGVYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5I1</accession>
    <name>A0AAD8Y5I1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_009945</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5I1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="353"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="390"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1739402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="480" mass="52646" checksum="9A3C5C38E9F86C37" modified="2024-05-29" version="1">MGACGSALMKPCLGETDVRYDANYPKTIVETDARWEKLTGYFKVNVTSFDPVDGGAAQPGPYIESVIQTHSSPFDASRTIAFYNHTVDGSRLIVNRYYFKPPAPFGFCQIPFEPPAMNAQPGSTCGVNGQVDFAGVYASLTHEHDGTLKIGRATGSYANSEDGIWDNDGEGSYAKLTDDSTFEFSSVRPDEFSSVSSFVFFDDDTATLSAVHTMIPMQRIVSANTATMVRISEEEFLAGIEEYNEAFQVPQPIQAPMTSDEVAKYDGTFPAEEDWCGGVMSDVSCTPSPYVEPDAQMKGGVIALFVILGVLLFSSVALFFHRKAIETQKKRYKEHFIRGIARNITISDSAGRVSPEQLKKEFDHIDKDKGGTISKDELKTFLKSGKVGDISDKDVEAMWAAIDIDNSGEVDFVVSLELKEFIAFLGSCGTEFDSISKEQKAMSKADKLKYASQRLSTRCLVMPPVVDKSADEEKEGEENA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y686</accession>
    <name>A0AAD8Y686_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfotransferase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009629</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y686"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053259">
        <property type="entry name" value="Golvesin-related_Golgi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32301">
        <property type="entry name" value="COUNTIN RECEPTOR CNR3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32301:SF6">
        <property type="entry name" value="GOLVESIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1739870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="208" mass="24703" checksum="FB79D351787AC5A2" modified="2024-05-29" version="1">MLPKYLRDTMPREKLSVMDVWDVDKDIAFFWHIPKASGSTLKNIMNFCFDLKRAENTDGLPSMEFKRNNILNMDTTSPDGLDKSFEYREEIFSSGIDLIVSNYFLAGHRGRTFTIMRHPIEIAQSLFHYRKKAKWERTYREDWNQITFKDYANTGQEHIEEKVFVGIADQMDETVRQLREYFGWKEKEPFCAFNYLHSNPSNTIRILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6F0</accession>
    <name>A0AAD8Y6F0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_008608</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6F0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="9"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="93"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="201"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="296"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="402"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="493"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="99"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="136"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="147"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="227"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="258"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="310"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="422"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="499"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="520"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1740513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="565" mass="61831" checksum="1527633DA8DC39F6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6N6</accession>
    <name>A0AAD8Y6N6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009045</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6N6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="202"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="237"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="311"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="351"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="437" mass="49841" checksum="88115AD6B205E314" modified="2024-05-29" version="1">MLASSDNIKNFLAHIAVHMKRPLGWRLAAIVEPSQSEANTLNMKSEDICSVMQSYLVWRRSSMLVSLPIMFYATLSGFLEMNRFREEEYDVLKEYGLASVVTFIYAVPSIADAVLFLGAIGAHTRWHEWHYTSRVLKYGWLVSTLLPLIPVFVPFGVFVSKTYKDKVFEECRQGQGFFDDYIVSSCDDFFQGTISTLKMTMAFYYGIKILPLILTFPSSCVRAALRIRGLIPDSSFSSWMISIAAPFQSMLILVSLIFLIQMAGNVCLVIAALLLCLSPWMYVIRLNLYVSISSDEREKQIDKNQNIMSCMYYGAIILLVVWAHTETLLGQPLIGPHSEEYTENPVMTYNYFFQLVFESFGRLLLTTVVFGDALLCMTVKNFQHNQCRIQHGATWQRVRETFKSLEYITQPKQNNDEADTDTAEQAEHPQALGNFQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y886</accession>
    <name>A0AAD8Y886_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_007936</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y886"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1741458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="220" mass="25522" checksum="8D35698D59892B6B" modified="2024-05-29" version="1">MKLWHHTDGPQFEEKGQVIELDIGDKRLPGGDTVNPEVLDFFRTGSDRARSYFQYYNIDYPDKTSRSEKEISLRRILPSMKERKSVLDRDIMAATSKNKTKLEALTVPELLVQIEETRKMLNSKKIDPQIRPEKKSGNKSEKIARLVELRSILFVMDKNAKGREEAEIIRQYKANGEVLKGNMRRILDDPMGLYAIHTSVLEKPRYKDPPELNDDSYIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8W9</accession>
    <name>A0AAD8Y8W9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_007856</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM151 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8W9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026767">
        <property type="entry name" value="Tmem151"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31893">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 151 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31893:SF5">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 151 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="487"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="563"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="499"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="563"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="576"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1741378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="592" mass="65369" checksum="00FF98CC1DBB0620" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y952</accession>
    <name>A0AAD8Y952_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007797</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y952"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="557"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="424"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="574"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="583" mass="64547" checksum="4812D6728999D956" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9C0</accession>
    <name>A0AAD8Y9C0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sel1-like repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_008081</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9C0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="14"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="79"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1741603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="298" mass="33210" checksum="2F71756B5F876992" modified="2024-05-29" version="1">MSAEAETIDDTSMCASCGNAAKDDVKLKNCTACHLVKYCGVKCQREHRPQHKRECRKRAAELHDEILFKQPESSHLGDCPICCLPLSLVPKTCIMMACCSKMICNGCDYASVIRKIDDKCPFCRHPTPENEEETDKDLMKRVEANDPVAVRNMGFKRYNDEGDNESAIEYLTKAAELGDLVAHFELANFYRDGECVGKDMKKVIYHSEQAAIGGHPMARYNLGCVEEENGRFERAVKHWIIAANLGDDKSLNALKKGYAVGRIQKEDFAAALRAHQAALDAAKSPQREAAEAARLNNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YA42</accession>
    <name>A0AAD8YA42_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Centromere protein S</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_007753</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TAF9 family. CENP-S/MHF1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YA42"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071821">
        <property type="term" value="C:FANCM-MHF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22919">
        <property type="entry name" value="HFD_CENP-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029003">
        <property type="entry name" value="CENP-S/Mhf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22980:SF0">
        <property type="entry name" value="CENTROMERE PROTEIN S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22980">
        <property type="entry name" value="CORTISTATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15630">
        <property type="entry name" value="CENP-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="136"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="194"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="217"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="281"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1741275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="293" mass="31535" checksum="2D8AD957A9951F85" modified="2024-05-29" version="1">MYAASFPSSSDHEDGSSSDDDSEVDETLVRELRESLHFCVGKICRAEELAAARDGDANKDDDESDNGMTTSISKKTDTVMSKEAISALTELAYHYSTSSLANDLCAFSNHANRRTVKADDVLLVARKEKHILAELKRKVAASQPPAEPSNKGGNSTAKAAAVGSKKKKNTNNTKKTSNPLFNSNKKKAAKSKSKSMMLDSSSSSSSSDSDSDAGLDPMEKIRQRRLELKQKNLNNTAFDRAKNNDDSSSSSSSDGLDFSISKSKTNGKKKGSNKPKGTVDTQDDMVIDLADSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAG9</accession>
    <name>A0AAD8YAG9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007948</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAG9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:001993">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052941">
        <property type="entry name" value="StomDev_PlantInt_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48004">
        <property type="entry name" value="OS01G0149700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48004:SF58">
        <property type="entry name" value="OS01G0162200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="683" mass="75649" checksum="A2E53484EDCD7486" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YB01</accession>
    <name>A0AAD8YB01_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006727</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YB01"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051860">
        <property type="entry name" value="Plasmodium_CSP_Invasion"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44826">
        <property type="entry name" value="SPORE COAT PROTEIN SP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="154"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="212"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="424" mass="44327" checksum="5FA80F0EEA1E5F80" modified="2024-05-29" version="1">MHTPAPNQFTPATAEDVEVVLNSTNSNARDIDVELANRSTGAGDVNISSANNLQTTEHVNLNSTNNVYKGMKSTIGVVTFISLGASVLVVGGYGIEASKSKSTQIQTNFSESDCVVTKAPSVVKAKSTKSPSSKTRSPTLSKSSKKKRRRCGKSTKAPSPSPTKSLSPSLSPSIKPSELPSELPSSRPSIQPSTSTQPSDQPSLFPSASVEPSMAPSELPSSSSRPSNQPSTQPSDEPSLFPSASAEPSMTPSCLSQPPPNCAQLYGGGWTRVRHVPAGITWHPATDSLAGTEVYGTESIDSAPWSVDFESKVAGYNEFLFATGDCTKWLVATTDAVIGETYGSASRPILASSDNASPYSAVWLNRANQVEDPWVSIIDHVPAIGAGKILYGENGYGGAHSANILPSSAGADVYVRVSTACISC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YC14</accession>
    <name>A0AAD8YC14_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_005273</name>
        <name evidence="3" type="ORF">QTG54_013589</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YC14"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010640">
        <property type="entry name" value="Low_temperature_requirement_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36840">
        <property type="entry name" value="BLL5714 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36840:SF1">
        <property type="entry name" value="BLL5714 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06772">
        <property type="entry name" value="LtrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="308"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="394"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="423"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1743676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="450" mass="50432" checksum="7A2B3F0A656D1BE0" modified="2024-05-29" version="1">MADPNFNYQSIQNQPHHEHEVTKDEEEEEPKVSTLELFSDLVIVVAIHVVATPLEESHFNEFGLYFARVFYLWLAWHMMTIFMNAAVLMKSSNCPIHNSFIFVWMAFILHMSQAFSVNNDMIAALWYLFLRAFETAIYWRSMIHPYKAIKLADGSMTLSVSDDWLKAMSDYIPVMVFTFIFCEFIPLSLAVYWGHHDDLYSPMVATSIVLIILSFFVGAVRAVGKQNGNQGQQQQMSKDANVINGFDVEHFEERYELISLIFTGELCFAAGTPGNSVGAYGVLFMAFSVYLLTFKSHPLNGVKFWARGILYSVAGLFLYAGIFCAIPAIGSAFVRIVESEQKEEEEEEVEGSVSAGELLCYSAGAFMILSAFLNLMHVDPDGSAAPKISLRNRGLIRIFVGLIIWSLSVLIPDKVEFQGAPLASIVVPFLALVTCSIEIWAVGSLKIAFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCJ0</accession>
    <name>A0AAD8YCJ0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCJ0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34044:SF3">
        <property type="entry name" value="KETOPANTOATE REDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34044">
        <property type="entry name" value="NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042176429" evidence="1">
        <location>
            <begin position="23"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="320" mass="35594" checksum="A7FB0D4CBA902B5D" modified="2024-05-29" version="1">MMRPGHIRLLLLLFYAAISSNAWLTTTHHSGLQRSRNSEISAHIQDERYPRGEVIGSSGKIGSFILNSINSPVVPIVEESNNHQYPQCQPAAATPRGVSPGCLSPGNTPLYACIPSSAIRTVWEATVPHRRKDLVFLCNCIPSRHLNFDSSIDFTICILHFGVSHASVDDKGTASSLQPLPILNTSPQSPPTVVYGRHATTLAEVLKRDGISVEIASSAQHLQIVAAKKLAWSSLFWLLCHDSNEPMTVKEVWECKSKQIHELVEEMLPALNRLASEPWTKYDDTELPKTSTKLSRLVRCKKLSTTLCLLHVNERWKNYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCV0</accession>
    <name>A0AAD8YCV0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCV0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="530" mass="58745" checksum="5C486242912007AD" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCV5</accession>
    <name>A0AAD8YCV5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Strawberry notch family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_005485</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SBNO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCV5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026937">
        <property type="entry name" value="SBNO_Helicase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026741">
        <property type="entry name" value="SNO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12706:SF30">
        <property type="entry name" value="PROTEIN STRAWBERRY NOTCH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12706">
        <property type="entry name" value="STRAWBERRY NOTCH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13871">
        <property type="entry name" value="Helicase_C_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Strawberry notch helicase C" evidence="3">
        <location>
            <begin position="188"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="26"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="100"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1743888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="506" mass="55512" checksum="77BB7658B9F2EA8D" modified="2024-05-29" version="1">MQMFPLPPKPAGVIAPEFLNHLKKDDIVGDDGTVDTDTASVSDNSLDLSLDSSRPSRRARKAVSYDERNVSSEGVILNLGKKGGAGKKAGKKRNSSSADSGDESDFTVDISGDELSDSDSDDDDDAFDLKKKTPSQSIAWNEIPLEYDETNMSIADRVDHKRKANYRRAAEKVKGWLDTVDSLSLPANPLDRLLNELGGPDQVAELTGRKSRQIKQYNAMTDKHEVIYQKRKGENCPMDQINIEEKNNFQNGTKLVAILSEAASTGISLQADKRVKNQRRRVHITIELPWSADKAIQQLGRTHRSNQTTGPLYKFLISDVGGEKRFASAVAKRLALLGALTQGDRRATGSANSLGLSAFDMDNQYGSRALQTMLREIWNCASESPLDGEVDDGLYVEALKMIDGHLKEALDGEERGEGTLEENLVPFDDDTEGEKTFRSMMYHLLTGPCQKLAASRVTAIREGRGLGIYFESLADGSEDKESVKAKIDAEFKSALDAGLNFNVSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD04</accession>
    <name>A0AAD8YD04_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">H/ACA ribonucleoprotein complex subunit DKC1</fullName>
            <ecNumber evidence="6">5.4.99.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_005896</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase TruB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD04"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000495">
        <property type="term" value="P:box H/ACA sno(s)RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990481">
        <property type="term" value="P:mRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031118">
        <property type="term" value="P:rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031120">
        <property type="term" value="P:snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02572">
        <property type="entry name" value="PseudoU_synth_hDyskerin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21148">
        <property type="entry name" value="PUA_Cbf5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2350.10:FF:000001">
        <property type="entry name" value="H/ACA ribonucleoprotein complex subunit CBF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="entry name" value="PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012960">
        <property type="entry name" value="Dyskerin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004802">
        <property type="entry name" value="tRNA_PsdUridine_synth_B_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032819">
        <property type="entry name" value="TruB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004521">
        <property type="entry name" value="Uncharacterised_CHP00451"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00425">
        <property type="entry name" value="CBF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003280">
        <property type="entry name" value="PRK04270.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00451">
        <property type="entry name" value="unchar_dom_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23127">
        <property type="entry name" value="CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23127:SF0">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT DKC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08068">
        <property type="entry name" value="DKCLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16198">
        <property type="entry name" value="TruB_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01136">
        <property type="entry name" value="DKCLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="domain" description="Dyskerin-like" evidence="5">
        <location>
            <begin position="40"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="PUA" evidence="4">
        <location>
            <begin position="289"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="407"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="21"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="456"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1743275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="477" mass="52892" checksum="2C2D10FF43D9ABE1" modified="2024-05-29" version="1">MGKSGESSRKKRKASDGQAEDATSSTSTMIAPSNHTPKLDTSKWPLLLKNYSDLHIRTSHYTPIPCGSSPLARKLKDHISSGVINLDKPANPSSHEVVSWIKRILRVEKTGHSGTLDPKVTGCLIVCIDRATRLVKAQQSAGKEYIGVVRLHSAIEDTKALHRAVETLTGALFQRPPLISAVKRQLRIRTIYESKLIEYDEKRNLGIFWVSCEAGTYIRTMCVHLGLLVGTGGHMQELRRVRSGVMAEKDNLVTMHDVMDAQHVYDTTKDEKYLRRVVMPLEVLLTNYKRIVVKDSAVNAICYGAKLMVPGLLRFADDIDINTEVVLMTTKGEAIAVGIAQMTTAVMATCDHGVVAKIKRVIMERDTYPRRWGLGPMAQRKKGLIKEGKLDKHGKPNDKTPKDFLEEYKSVEGASKPPALGSNGETTPAKTKVEEVKSEAPTPMDEDSGSSDSEKAKKKKEKKKKKEGKKKDKKKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD07</accession>
    <name>A0AAD8YD07_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Outer dynein arm intermediate chain subunit-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_006174</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein intermediate chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD07"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036157">
        <property type="term" value="C:outer dynein arm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045503">
        <property type="term" value="F:dynein light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036158">
        <property type="term" value="P:outer dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050687">
        <property type="entry name" value="Dynein_IC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442:SF11">
        <property type="entry name" value="DYNEIN AXONEMAL INTERMEDIATE CHAIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442">
        <property type="entry name" value="DYNEIN INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0243">Dynein</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8" id="KW-0505">Motor protein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="577"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="65"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1743553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="733" mass="81763" checksum="59464F1CE0BA732E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDM5</accession>
    <name>A0AAD8YDM5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MBD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006687</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1743090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDM5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.890.10">
        <property type="entry name" value="Methyl-cpg-binding Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="237" mass="25671" checksum="8A94776D38CCF527" modified="2024-05-29" version="1">MIRLYEEAKAKENAAEKEKAASKKSDSTKPSPSKKAKGSSKKDDTKADEGESAKKPSATEGGKSAKKKAKATDSEATKVSKKKRKAPTDSETSDAPKSPTKKKAKTSKADKSTPSKADDKKSTATKNGESEKKKRGPKPKDYAGIPSEPAKDLPEGWTLKNIPRSVGDKYDQKWYSPGGIAFRSKKGAMSFIEIANGGKDEAAAYVLFEKEEKKAKELRKAEREEKKKKDGAESVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDW4</accession>
    <name>A0AAD8YDW4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005292</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDW4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1743695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="69" mass="7510" checksum="7E9653DD2CA50696" modified="2024-05-29" version="1">MGPWKNAASGKDVLVWSTKCIRNLGAEYPVVKARGLINASARDVVDLLRDSSKVTIYNKSSLGEKIKSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YE11</accession>
    <name>A0AAD8YE11_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cell division cycle protein 16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_005319</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YE11"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045842">
        <property type="term" value="P:positive regulation of mitotic metaphase/anaphase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558">
        <property type="entry name" value="CELL DIVISION CYCLE 16,23,27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558:SF9">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 7" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="626"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="660"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="558"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1743722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="757" mass="83828" checksum="602F3816B987E379" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEI4</accession>
    <name>A0AAD8YEI4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fatty acid desaturase family protein</fullName>
            <ecNumber evidence="7">1.14.19.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_005358</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the fatty acid desaturase CarF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.-" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEI4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052864">
        <property type="entry name" value="Chloroplast_FAD_CarF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019547">
        <property type="entry name" value="Lipid_desat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48140">
        <property type="entry name" value="FATTY ACID DESATURASE 4, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48140:SF1">
        <property type="entry name" value="FATTY ACID DESATURASE 4, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10520">
        <property type="entry name" value="Lipid_desat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Lipid desaturase" evidence="6">
        <location>
            <begin position="160"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1743761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="350" mass="38261" checksum="3B389276EC964E96" modified="2024-05-29" version="1">MKITTAITLSAATILSSHESTAFTAPRAHQLIASSKGFSTLRSTLVDETDTITKQQLTEEQTQENYITETVANTQKSFQDDGFVFGLEGSGLERVKGRGANVVVEGDSLETTPQQVAMVSGTIAGQALIAANAIHELYTHTNGNAPVTALISLATIVSSWVAADLGSGILHWSVDNYGNGRTPVMGNIIAAFQGHHSAPWTITYRGFCNNVWKLCIPFGLPTVAAISFVAGPENPMVSLFFSFFCFSEIMSQELHKWSHMTKKEVPAIVNTLQDLGITIGRVPHAQHHMAPYDGNYCIVSGFCNEALDNSGFFRWMEHRIYEINGVESNAMKLDPELRAKTLRGEYRLTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEN9</accession>
    <name>A0AAD8YEN9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_005197</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45641:SF19">
        <property type="entry name" value="NEPHROCYSTIN-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45641">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="829"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="955"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="997"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1284"/>
            <end position="1317"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1326"/>
            <end position="1359"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1410"/>
            <end position="1443"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1449"/>
            <end position="1482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="177"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="83"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="205"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="262"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="290"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="337"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="368"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="383"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="432"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="488"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1743600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1568" mass="171993" checksum="9D7AEEEF82BD62C4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YF16</accession>
    <name>A0AAD8YF16_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004617</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YF16"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1745326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="125" mass="14425" checksum="17CA3B822E9EB020" modified="2024-05-29" version="1">MLPMQATCYSSVDEINLVVKSLLQTYLPSIIQKYKLLMLLVHSFKIDIKRRLCAHLTRDQVIETITPMLLAATTPKKTQKRSMDANFQSIFLILILPFALKSSRLSVAYRYYPDKSGIKISMWLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFJ9</accession>
    <name>A0AAD8YFJ9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005053</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFJ9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="11"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="114"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="23"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="234" mass="26288" checksum="13BC36010887B20A" modified="2024-05-29" version="1">MTFKEMFFARRVASKSKQNTGTEADDWSNQDEDERVDSFEESRDELNPLERFISGAASVFSGAATEVGSVVEDVTSIIAADAELDAEKEVKKSLSKSNKEREEWKKVKGSPSTLAKELKKLDKLERKVEKAEKQIMKNIMKTEKQIDKAEQEQTKTRLKIKALSHKFELQSMMKDGDGDDNDEMADERVREVLKDGVDGLSVAGEEVVGYVPRLVTSVNRTATKKIFPVDGDCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFR0</accession>
    <name>A0AAD8YFR0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004344</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFR0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="278" mass="31201" checksum="8001D53B1923C787" modified="2024-05-29" version="1">MSSFSVLNDVDEQTSKTILGSDGAARWQDFRSGSKIKATTKIRSGLGTQSISDERATEAKIRKDAGDRELHAGYTEFQRKNDHEEIAAQKKRKLIVDRVRPDDMPYFLPAETFEGFKFDYVFTTKSRGTGYYWDGWDSMKRELGEDKPDANNDTSDTLVTAEDDQVNPKVKKKKKKKRKLQETIIESDQFNPMEQVNIALRRKQAALNASAPTQRREVSVSDAVALGASSNELKSTAKEALTESEALPSGWECANDPNSGKTYYFCRTTAREAGQNLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YG93</accession>
    <name>A0AAD8YG93_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003486</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YG93"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="62"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="376" mass="42209" checksum="41C4B6DE244D91A9" modified="2024-05-29" version="1">MPMTPLAPPRSNPRGRSKSRPRSSTASAAAPSVKNPPPPPPPPPPLPFDPIIARVYGPTVNIYKDIFQVSSDANQEKVNEAYNRVWKEEQLKLDRVADDVALRKSTRLQIDATFAAYQILMNTEKRKKYDKAIGLVVEQPTFVTMTNQKREDYVKDLFEDDEDDDVKPSVARKIEYVQPSLSLTDFSTPIMQRKLPVVSPEFKVPPAEVHEFVQRFSLDEAFIIDGQVDSPAAVSIFDKSRIADSSPTEVSEFDVFRIANNDDDDDDDASYTSLHKSGGKKKSQRSRKSRKGKSSRREREKQGEIASRDRDTESDEDSFVHEESNVDACVDILQESFAHEESNIGACVDIFGLYLNALPCVQSADDDDEEESVLYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGQ8</accession>
    <name>A0AAD8YGQ8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diacylglycerol O-acyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.20" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGQ8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004144">
        <property type="term" value="F:diacylglycerol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045034">
        <property type="entry name" value="O-acyltransferase_WSD1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31650">
        <property type="entry name" value="O-ACYLTRANSFERASE (WSD1-LIKE) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31650:SF1">
        <property type="entry name" value="WAX ESTER SYNTHASE_DIACYLGLYCEROL ACYLTRANSFERASE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="265"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="538" mass="60359" checksum="D2CA4935C0C0F090" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGZ1</accession>
    <name>A0AAD8YGZ1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NUBPL iron-transfer P-loop NTPase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_004645</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGZ1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02037">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000808">
        <property type="entry name" value="Mrp-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044304">
        <property type="entry name" value="NUBPL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961">
        <property type="entry name" value="IRON-SULFUR PROTEIN NUBPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961:SF2">
        <property type="entry name" value="IRON-SULFUR PROTEIN NUBPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01215">
        <property type="entry name" value="MRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="376"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="457"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="458"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="472"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1745354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="585" mass="62796" checksum="ECFB4E9EE2587E4B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YH32</accession>
    <name>A0AAD8YH32_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YH32"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="242" mass="26912" checksum="FC5F0F41B50F0871" modified="2024-05-29" version="1">MRLRKEFQRRADTNKSAASSADSCPAVADEEDAPNPVPAVNDDDMTAGDKNDGTGQDDKEDDEDVPLGKHYMVFMCQTWTTTGGPSRFMVARYCLGGLSSRWIRSHVLQITAVLAVYGFVVNANGFDGATENRGAMKQLLTLTLLEVAPSLSDGCWPENFDTLPPTYRDVPEEEEVEPPLVEMVDDGYCEYEAHVTPPKKYSFFQLPWNLKVAYKHPIFVEILIYPTADWPHGVRSRSIGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YH33</accession>
    <name>A0AAD8YH33_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SUMO-activating enzyme subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004483</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YH33"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031510">
        <property type="term" value="C:SUMO activating enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019948">
        <property type="term" value="F:SUMO activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF162">
        <property type="entry name" value="SUMO-ACTIVATING ENZYME SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1745192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="320" mass="35569" checksum="B31F70286C490B02" modified="2024-05-29" version="1">MGPRADKHDDVYDRQIRLWGADAQKKMSNARVLYINLTGVTCEIMKNLCWRVLRCCFARDAVLFFSCGRYGKAASENGSSQCTVAKSVQPKVEELNPLLAGRNSIEERPIAELSDDFFTQFDAIVASRLTVEEAKRISTSLQKVDEGKLFIVTDTFGFDGCAHLDFGASHKYRRELGKDKLSDMMPVEPYLSMADMMSVPLESATGRWDKSVPRILVLHRLLMDYWSLVDKPEFVKFAQDWLAINKLSSSALSSDVQDCSLETLGEIAQHPEVSPVCAVLGGILGNEVIKSLTGKGEPANNVMMFSGFDGGCRSFLLKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YI10</accession>
    <name>A0AAD8YI10_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_003485</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WSCD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YI10"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051589">
        <property type="entry name" value="Sialate-O-sulfotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45964">
        <property type="entry name" value="WSCD FAMILY MEMBER CG9164"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45964:SF5">
        <property type="entry name" value="WSCD FAMILY MEMBER CG9164"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfotransferase" evidence="3">
        <location>
            <begin position="144"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1745561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="368" mass="41638" checksum="943EC768C06A079B" modified="2024-05-29" version="1">MQQSPMQQQEGKTASRSRRAASFVAATAGLLCFLIGTSVMYTTNRSSSSVVAVTNPNNNPDIEEASSLSSSTSLLRPSRRALSELVRVEDGEDLCSYKRARLIAVSLAEHDVSPTYQASFPGSGARMTHELIRALTGIAISTDHAYAVETNRHRHSVAVKTHYPDPNGVPLDEFDEHFNGAVLVLRHPAKAIPSFFNFWYERVHHLANHSTRAPLEEWIKFRDTSLVRQLQHYQQHMDFWMLKYEQNKEKLLVVTYEDMTDDVKGPETTARIAEFLNAAEGVQTVPPESITCIWQKVVKYEDIGIKLKYGSHRTGGPKSNPYTDIQLYAIQLMMQEQRIKFQNDPDMVAIMDRYISMTLEMQPELVTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YI26</accession>
    <name>A0AAD8YI26_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD/NADP octopine/nopaline dehydrogenase family protein</fullName>
            <ecNumber evidence="2">1.5.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003399</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YI26"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051729">
        <property type="entry name" value="Opine/Lysopine_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003421">
        <property type="entry name" value="Opine_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38015">
        <property type="entry name" value="BLR6086 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38015:SF1">
        <property type="entry name" value="OPINE DEHYDROGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02317">
        <property type="entry name" value="Octopine_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Opine dehydrogenase" evidence="1">
        <location>
            <begin position="64"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="266" mass="30402" checksum="E09FEF7A12835AC5" modified="2024-05-29" version="1">MEAHIRGLVTYTAVHCPLITDNAPSTSSCYCSVELFGLEGQTFVTPVILRYVIDDMFDYYLPCSFLSLTLSVDNQIIHPCRCYGLWKRYGGKWAAEDDIPFFYKDFDDVSAECMMLLDADYSSVRDAVRKAFPDREFKYMLDYLTLERVTHNSKHANIKDSFKNSEQLALIKTPTMKLDDGTYALDTEGRFFTDDIPYGVLIARWVGQEFGVETPFIDEIIEWAGSMRGEHFLKDGKIDLDYCLREIGKTGIPPAYGITDVKEILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIH6</accession>
    <name>A0AAD8YIH6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein MON2 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_003740</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032629">
        <property type="entry name" value="DCB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032817">
        <property type="entry name" value="Mon2_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16213">
        <property type="entry name" value="DCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16206">
        <property type="entry name" value="Mon2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mon2/Sec7/BIG1-like dimerisation and cyclophilin-binding" evidence="4">
        <location>
            <begin position="3"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="Mon2 C-terminal" evidence="3">
        <location>
            <begin position="1248"/>
            <end position="1357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="167"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="515"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1048"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1887"/>
            <end position="1935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="515"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1745816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1938" mass="209366" checksum="A697548E782ED0B0" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIK8</accession>
    <name>A0AAD8YIK8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Chlorophyll a-b binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_003669</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated. Energy is transferred from the carotenoid and chlorophyll C (or B) to chlorophyll A and the photosynthetic reaction centers where it is used to synthesize ATP and reducing power.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fucoxanthin chlorophyll protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIK8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030076">
        <property type="term" value="C:light-harvesting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="8" id="KW-0157">Chromophore</keyword>
    <keyword evidence="7" id="KW-0437">Light-harvesting polypeptide</keyword>
    <keyword evidence="5" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041990848" evidence="9">
        <location>
            <begin position="16"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>3</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1745745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="265" mass="28365" checksum="AB7437110EDF3754" modified="2024-05-29" version="1">MKLAIIATLVGSAAAFAPSGNTVRMQSSIRSTTEDEVTEVAAEAAAAPLPDIVPEPVVAPINGWVPNESLPCYGLPGALAPTGFFDPLGFAQSGITLNDVKRNREAEVMHGRVAMLATVGYFAGEAISGPFNIHGPANDQLQQMPAPAFAFLTLSIAAAELRRATIGWVEPDFGDWTKTLWAIRDNYYPGDIGFDPLGLKPTNAKDFANMQTKEIQNGRLAMLGWAGMCSQELVNHRTILGTIDFYNKIYSGVNPYESCVDGVVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJ26</accession>
    <name>A0AAD8YJ26_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_001467</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJ26"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.20">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="166" mass="18776" checksum="B18B762ABAC9E64C" modified="2024-05-29" version="1">MSAAQKYPAPAVMGPESIMSKKAHGTSATPVQENLRWKVDQEVADRICNFNRHYAEYSGYFQNVPEFMNQTNDTPADKEITFYDSNTGKPLFYAPRGRTMEQFIKESRNHGWPSFRDDEVEWKNVRLLENGETVSVDGTHLGHNLPDGKGSRYCINLVCVAGNPTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKB6</accession>
    <name>A0AAD8YKB6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKB6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="98" mass="11312" checksum="423605BC7A65366E" modified="2024-05-29" version="1">MKDEGDSNETNDATSKESSEGAIEQEEETSNQRSIKRLKSQLQHYKQQNEMEKKRRQKVVSSFVSFHTMYESGLDFIARMGDLRNVPDNVMGDEIPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKN0</accession>
    <name>A0AAD8YKN0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Protein-serine/threonine phosphatase, PP2C family</fullName>
            <ecNumber evidence="8">3.1.3.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_001731</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKN0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47992">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="7">
        <location>
            <begin position="254"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="75"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1747768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="599" mass="65575" checksum="40B957BC88F80411" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKN6</accession>
    <name>A0AAD8YKN6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PITH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_001252</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKN6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.470">
        <property type="entry name" value="PITH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010400">
        <property type="entry name" value="PITH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037047">
        <property type="entry name" value="PITH_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06201">
        <property type="entry name" value="PITH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51532">
        <property type="entry name" value="PITH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PITH" evidence="3">
        <location>
            <begin position="22"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1747289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="193" mass="20979" checksum="DEB718BCAE3C1401" modified="2024-05-29" version="1">MFPSLGGATANGGPGAAAAEPAPAKDGEGLINLCDMLDKPMCYARNENTSYPLGNLFIGDSRLGMQSDADEQLIIHLTFQEFVKVKSIKFSEWNMGSNPDMNPVNVHIHINRNNLGFEDIEDVDPAQTITLTAADLQDVSDAIDLYYVKFQRVKSLTFFIEDNAGADITAIGGLQIMGRTVATTNMNDFKKQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YL80</accession>
    <name>A0AAD8YL80_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MORN repeat-containing protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YL80"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23084:SF263">
        <property type="entry name" value="MORN REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23084">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="19"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="385" mass="42310" checksum="9E937D93FD8D625B" modified="2024-05-29" version="1">MSDASSGAMAPPPAKKVRSCSSSESTPNISSESHSTPGLSTTGLSSLDETTAATLIDAARRYEIEASLRHRQSQEEVSSAKEEVLAAMETLKRAHERLGKAEAVAADATKSYKVATEFKTKWELQLNVGKKPAPILSSSEHDEEQKHVSFAPQHEISGPSSIGSTGRKVKRIRIRVSEHGWGMYEGLLDSVGEPHGRGTITWENGGRYDGEWCDGKANGHGIMDYANGDRYEGKWKDGCRFGQGTHHFKDGGVYEGQWRNAAPDGQGKMTLKNGSHYEGSWKDGKWHGPGIVRPVNGGEWEGTFQLGKCTVGTLRRPNGELEIGRYESVNPDDVKEGVWWSIDRQKIWKVENGQKKEEINFVMALEIASQIGVQLPNELLKSDDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLY2</accession>
    <name>A0AAD8YLY2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Hexose transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">QTG54_001738</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>D-fructose(out) = D-fructose(in)</text>
            <dbReference type="Rhea" id="RHEA:60372"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:60373"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-galactose(in) = D-galactose(out)</text>
            <dbReference type="Rhea" id="RHEA:34915"/>
            <dbReference type="ChEBI" id="CHEBI:4139"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="8">
            <dbReference type="Rhea" id="RHEA:34917"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>D-glucosamine(out) = D-glucosamine(in)</text>
            <dbReference type="Rhea" id="RHEA:78423"/>
            <dbReference type="ChEBI" id="CHEBI:58723"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:78424"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-glucose(out) = D-glucose(in)</text>
            <dbReference type="Rhea" id="RHEA:60376"/>
            <dbReference type="ChEBI" id="CHEBI:4167"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:60377"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>D-mannose(out) = D-mannose(in)</text>
            <dbReference type="Rhea" id="RHEA:78391"/>
            <dbReference type="ChEBI" id="CHEBI:4208"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:78392"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-xylose(out) = D-xylose(in)</text>
            <dbReference type="Rhea" id="RHEA:78427"/>
            <dbReference type="ChEBI" id="CHEBI:53455"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:78428"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLY2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF12">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="18" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="82"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="200"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="378"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="404"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="459"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="492"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="524"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="17">
        <location>
            <begin position="8"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="240"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="587"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="263"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="596"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00044780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1747775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="627" mass="68071" checksum="6F656860BECDFED9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YM69</accession>
    <name>A0AAD8YM69_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="5">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_001105</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="5">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YM69"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="314"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="8"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="67"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="91"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="135"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="162"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="196"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="212"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1749166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="450" mass="49570" checksum="04D88BF7D1D6ACAF" modified="2024-05-29" version="1">MEPEDTQSEYPSRSLSSKSTVFDTQSEPPGISYLKVDKIKRRDSSGRSVKSSASSIRPAATVESPTSVCADSRSVVSSSSNASKLDAKLQSSTRSLNNAASSRASKSRDVATAASSKKKDPSLPSSNRSVKSKSSKSAPSSSSNNKLALVPKSKANDPPTKGDSTAYSTMAESLDDEQQKPSPSEFQIIEKKGANRLSTIDSASGNESSDQNYDENDDDQSGDSYTRVSALAFELERALVERRDTLNSQQSDQLVQYDVGNNLVSEGGAETALVSAKERYLATAVDNMGSMVPMDSDIYEAYDHTFVTCPEYLRFRFLYTFLRKNLDKKMMVFFSTSTSARFHAELLKRLRVPVLTMHSRQRREKFISTFFKFSDMKEGILCTTDAAGRDLDVPPSVDFVLQFEPPDDPSEFILRIARISCDSDRIGRSILFLNPGSRDFSSTTLRLLLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMH1</accession>
    <name>A0AAD8YMH1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mitogen-activated protein kinase kinase kinase</fullName>
            <ecNumber evidence="8">2.7.11.25</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_002008</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.25" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1748045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMH1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004709">
        <property type="term" value="F:MAP kinase kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06606">
        <property type="entry name" value="STKc_MAPKKK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050538">
        <property type="entry name" value="MAP_kinase_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047365">
        <property type="entry name" value="Tudor_AtPTM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016">
        <property type="entry name" value="MAP KINASE KINASE KINASE SSK2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016:SF56">
        <property type="entry name" value="MAPKK KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21743">
        <property type="entry name" value="PTM_DIR17_Tudor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="867"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="238"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="386"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="731"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="55"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="253"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="272"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="286"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="386"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="439"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="455"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="496"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="538"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="734"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="896"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1748045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1280" mass="140151" checksum="52F75C31178B5E9F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YNQ0</accession>
    <name>A0AAD8YNQ0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Coatomer subunit beta'</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">QTG54_000773</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Cytoplasmic vesicle</location>
            <location evidence="1 13">COPI-coated vesicle membrane</location>
            <topology evidence="1 13">Peripheral membrane protein</topology>
            <orientation evidence="1 13">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Golgi apparatus membrane</location>
            <topology evidence="13">Peripheral membrane protein</topology>
            <orientation evidence="13">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="13">The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the WD repeat COPB2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YNQ0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22947">
        <property type="entry name" value="Coatomer_WDAD_beta-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000016">
        <property type="entry name" value="Coatomer alpha subunit, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.470:FF:000001">
        <property type="entry name" value="Coatomer subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006692">
        <property type="entry name" value="Beta-prop_COPA/B_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050844">
        <property type="entry name" value="Coatomer_complex_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016453">
        <property type="entry name" value="COPB2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056176">
        <property type="entry name" value="TPR_COPA_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876">
        <property type="entry name" value="COATOMER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876:SF2">
        <property type="entry name" value="COATOMER SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04053">
        <property type="entry name" value="B-prop_COPA_B_2nd"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23953">
        <property type="entry name" value="TPR_COPA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005567">
        <property type="entry name" value="Coatomer_beta'_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 13" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="7 13" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 13" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 13" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <keyword evidence="5 14" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="15"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="99"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="176"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="220"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B second beta-propeller" evidence="16">
        <location>
            <begin position="333"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B second beta-propeller" evidence="16">
        <location>
            <begin position="411"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B TPR" evidence="17">
        <location>
            <begin position="533"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="792"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="15">
        <location>
            <begin position="794"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="842"/>
            <end position="872"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR005567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF23953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1748834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="939" mass="101962" checksum="409D41BAE3BEEC5C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YP87</accession>
    <name>A0AAD8YP87_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_000821</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YP87"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12565">
        <property type="entry name" value="RRM1_MRD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12320">
        <property type="entry name" value="RRM6_RBM19_RRM5_MRD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10352">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="8"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="301"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="587"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="92"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="183"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="498"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="526"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="663"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="194"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="255"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="526"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="544"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="672"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="683"/>
            <end position="692"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1748882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="692" mass="75997" checksum="678D07595D5002DC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPH1</accession>
    <name>A0AAD8YPH1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPH1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="432"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="454" mass="48744" checksum="91E6E3E4AB109475" modified="2024-05-29" version="1">MSFFSLSATPGLGPIFSLTHHLLLEKSQVPSHGNNLIYEAIDAGWGGVGGVPVAAAAAGIIITIATTVNGDGHFITKYYVPEYRLRVNIYRFMSIGMICVRRLRCHDGTGRDGDKCYWGDANGNEGKFNPTSFHESDGLDKPFGRDSNSSSSTTSSGKPSLARPSLRASADDASEAMAGLKTEGDISFDSTTGPHPLHVDSDANMSDCVDKALVALNIAASLIKKDRVDARRLGMEEEHSGGLDGEDDADALFDESAGLGIRETILEMIMEDDQGSEDDEEIEKDLEQCFAHNGVSERSIHSSSGSTQHGAFGGDDNDTKPSPPRKPSPTRMRAASEPAVSPDRRVAKKFIDETSSTFGVDVLSSLIRILGQARANPHDAYHSARCLGVLLRGAETLTDAKRIVSAALEVGSRTHAKLADASRVAMVALVTDDDQSMEEVQEEEEEQTEQSEQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4B7</accession>
    <name>A0AAD9D4B7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">OTU domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016859</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000066">
        <property type="protein sequence ID" value="KAK1732465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4B7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22744">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OTU" evidence="1">
        <location>
            <begin position="128"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="338" mass="38677" checksum="BF7E00FBA8159880" modified="2024-05-29" version="1">MHIRHCFYSDLDMDAISISSGSSNDDNGSVDSHMDILIEPHHIDFEQGDLLRLNGGVLDDPQAINQNDMWVHDPNQEEGADVSFADESMENLDAADFHEETLFPAETAARAFAAAFGMFVVTSTMRVGTEQDVKGDGNCFFYALIFGMFHLRAHPYYILSDTDQDGHRNLRMRLRDVTGFRRAILDYLTTNINYFNSPDAHDRRVHDSLGNRCRDFSGRIEYILETEDFIGRRLFEENIDYPTQCTYHHWADINQHLPVLAMYLNTTIVCYFDSEKEGKSGSLGNTTVAHFHEGSVKMHYLPGEYYAPPQSIPSICIRYRNGNHFTHIKPFSCTVRHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4Q2</accession>
    <name>A0AAD9D4Q2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015532</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000045">
        <property type="protein sequence ID" value="KAK1733677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4Q2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35213:SF5">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35213">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="372" mass="40706" checksum="5D75B2B511E47871" modified="2024-05-29" version="1">MSEEQKRDDGDSCTSEASQDNMTKALPTISDGSQPMALLPADISSPTNNKSGKDNGTDESNPTPGSQSEQNKTNLRRGKWTPEEEAYARAVICDFNTGYLDAPIGTTLRAYLSGKLECDPMRITKKFTKDDSIGKKVFRPAAQHDAKIAKEVKDAQAKVVALYQNWKRRIETQKEETNRKSSVEASLTDGIIRTSNFLLDIPQTRNITHNVTPETMALVNRTADWLEKADDILSKISNGGRPTEEAATEMKEIKSLIDQGPTVLAAVGDVTKILKDVKAKGLPSRLHSCPDFRKISGASSPTAKKRKHPLIDDELVKSYDSNPINLLASLSSRAAPVPVSNGNAKQRKRKGSEVNPEDANAFVSFLQSVAHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4T5</accession>
    <name>A0AAD9D4T5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000055">
        <property type="protein sequence ID" value="KAK1733019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4T5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="163" mass="18248" checksum="1DD834C5F638DA4C" modified="2024-05-29" version="1">MSRRPTKATASSRSNAATFSTGYERPPTSSHLDLSSANDDDTTIASGGSKIHKKSKQQLRRKGSSMLFATACCLISLCTVYYVVIQFTYMAKHHVNSSLAIHHEQQMEIPQDDENEPNNHLHHHLHLPPDSIYRTELTDIHNKPQSLLQYSGFISLIVNTACE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D687</accession>
    <name>A0AAD9D687_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phytanoyl-CoA dioxygenase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_014737</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000038">
        <property type="protein sequence ID" value="KAK1734489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D687"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883:SF15">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1734489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="364" mass="41548" checksum="D5B60BB436CCEF82" modified="2024-05-29" version="1">MSCAGSLKAYGRDAPFKDIYETYQKDGAVIVHNLLSKEEIQCFRDEVRGTLKTTDAGARHSHVHVNEDQQKFWGNNTIRFSQMATRSRTFRNKYLVHPLLIQMADAELVSNEYWLNTGQVMCIGPNSEAQELHRDAEHWPSMCKSREDEAIQISFMLAVDDYTEETGATCVVPGSHNWDDYSRTPESYEVVQAAMPAGSVLTYSGKVIHGGGPNSTQDRWREGCHLSFLSRWLVPEEAACLSITKEDALKLTPLQQSLLGWKSYTEGEHELWTLDLDDPLVALGCDTKIMSLQDKFYEKYATDEEWVDGFVFADCASVYVSGMDSLDEYFDLELDYKQRKSLRRKLKKACFKQTKGFEDEVFLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D754</accession>
    <name>A0AAD9D754_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012683</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D754"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="113" mass="12233" checksum="BC8B5976131B2FAA" modified="2024-05-29" version="1">MSPQYGFYVNITPPTTLHAASRKRGSPLRPFEESSPQQQSFRGFSPFLPSPIPEVELAKEMGGAPTLAPLSASLESSAGKNRLKPSFPKNRVAMGMVLAGNHHHHAWPSIPMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7A5</accession>
    <name>A0AAD9D7A5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012609</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7A5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35716">
        <property type="entry name" value="OS05G0574700 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042127749" description="SnoaL-like domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="203" mass="22562" checksum="362AA820DA8FF4D3" modified="2024-05-29" version="1">MMDRLMIRFPFAALVIQTILLSTAQAFLLATHPRQYQSSYLSTTNANDAPEDANINRGNSPLSAANVTARDVVVACMDGLLNNDTPWANSGLEICWDYSSDRNRAAQGGSFDEFITYASNPTFSTMVNAKEFSIENVGAYIKGTNTRGAMQTVLVKVQPLQGEERSFLWTMAQERRPPRQGLWLVHECINLENAIGLNLDFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7S1</accession>
    <name>A0AAD9D7S1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alpha/beta hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_013095</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1735959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7S1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047372">
        <property type="term" value="F:monoacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034338">
        <property type="term" value="F:short-chain carboxylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050960">
        <property type="entry name" value="AB_hydrolase_4_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012020">
        <property type="entry name" value="ABHD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10794">
        <property type="entry name" value="ABHYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10794:SF63">
        <property type="entry name" value="ALPHA_BETA HYDROLASE 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005211">
        <property type="entry name" value="Ab_hydro_YheT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042126839" evidence="4">
        <location>
            <begin position="20"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="5">
        <location>
            <begin position="174"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="21"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="2">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="2">
        <location>
            <position position="396"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="2">
        <location>
            <position position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR005211-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1735959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="465" mass="51503" checksum="495540730D21A264" modified="2024-05-29" version="1">MKNCILLVLQLVAVASCFSAPSKPGSFSTSSSIPPPLEPRRNVASPDEDLRKMQQKHRPIAASFTPSNFNPHPALNNKHLQTIGGVFLRKNLDCAYVKEGVGGITNVLQAVASIALPSSTKLMGDEALGDDSTSTFWDERQRITSCCSQDFFSVDIKYASERKTTLQSVESNGLVVLIHGLESNSNSSLSTDMAAAYLNDGLDVVCINFRGCCGSPNDTIGGYHLGFTDDLKHFLKIISNLWDEDELFEKRPIYLSGFSLGANVVTKCLGELGEAALTLYNIHGAAVCGAPFDCERNIKYFESPGFNRAVYSQNFLKTLKKRAQEQLDQHCDGDPNTTAFDYQRAMAATTVAEVENAFIAPIYGFRDNIDYYRCTSCYYYLPGVAVPLYIINAQDDPFFDPEFYPIEETVDGGSLAPVKLLRTKHGGHLGYLFHQLEENETSQDKEASWMPLELARFIRHVRESQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D816</accession>
    <name>A0AAD9D816_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_011743</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D816"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045877">
        <property type="entry name" value="ZFP36-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547">
        <property type="entry name" value="CCCH ZINC FINGER/TIS11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547:SF18">
        <property type="entry name" value="PROTEIN TIS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="53"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="106"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="53"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="106"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1737457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="591" mass="66225" checksum="5946E85B492EDBBF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DA08</accession>
    <name>A0AAD9DA08_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DA08"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="374" mass="41237" checksum="6C2BBDAD17D64F4B" modified="2024-05-29" version="1">MGGLRPSRKSTQPRLQEANDADAENVEHCSSSETPSSSTVVESTTTETLQRDAWTARGKLLLQFHDAISRAINSPEMKQKCSEVASYMSTKEEPEESSPVNHEYDAEATLIVQNKHKRDNDVRDKAVAVGFCTFALLRGVPIVRNVVARRMASASRYKFEAASSQQQRNVSRTTMQKSTQQPASGSPSRLRKFLRLTLDVTISAAMTVLSGTFLFTPRPSAYIEDMSKLPLVEGKSVYAEVVCPPLLNEYKRTMEQYGGRWPVMTRGVEGSSSSSSSSSPAATVATTANSPTLTQEDVSLNIIRKFAENCSKRIKYERAILEEQNALDEQKQKKLGTVLIPRPVPEDVKVNIDEDVFFLVDDDAAKDGSACIEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAV5</accession>
    <name>A0AAD9DAV5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">mRNA cap guanine-N(7) methyltransferase</fullName>
            <ecNumber evidence="10">2.1.1.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">mRNA (guanine-N(7))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">mRNA cap methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_010396</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 5'-end (5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:67008"/>
            <dbReference type="Rhea" id="RHEA-COMP:17166"/>
            <dbReference type="Rhea" id="RHEA-COMP:17167"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:167617"/>
            <dbReference type="EC" id="2.1.1.56"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.56" evidence="10"/>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAV5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004482">
        <property type="term" value="F:mRNA 5'-cap (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004971">
        <property type="entry name" value="mRNA_G-N7_MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016899">
        <property type="entry name" value="mRNA_G-N7_MeTrfase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039753">
        <property type="entry name" value="RG7MT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12189:SF2">
        <property type="entry name" value="MRNA CAP GUANINE-N7 METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12189">
        <property type="entry name" value="MRNA GUANINE-7- METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03291">
        <property type="entry name" value="mRNA_G-N7_MeTrfase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028762">
        <property type="entry name" value="ABD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51562">
        <property type="entry name" value="RNA_CAP0_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10 14" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7 10" id="KW-0506">mRNA capping</keyword>
    <keyword evidence="3 10" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 10 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MRNA cap 0 methyltransferase" evidence="13">
        <location>
            <begin position="32"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="257"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR028762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR028762-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1739080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="431" mass="48235" checksum="AA1FD4B537BC37B8" modified="2024-05-29" version="1">MKEGTFHANAGAAAADAFYSGLTRTLDTRADSRLYHMRAFNGWVKATQIAELDPDISSAANNGKKRSRRAPLRVLDLACGKGGDLGKWTLHQRGVENYVGVDVARGSLIDAAIRARTMSKRKTCKLRKCTFTLADLGEDVPGRKRSKNANKMQKLLTWTMQNETNEEKEVDPKFVALEGGGIAETDKFDVISIQFAIHYMMQTRKRARRFFHTVSSLLEIGGNLIATTIDARVVIEKLMALGLDLHFDEMDQHEEVDKSSNEEIHHNGNKRRKVNDENEVTVKVGNGVCRLKFDPAVVRKVFEPSNSIEEMFGLQYTFTLVEGSDHAAGVGEAVDLPEWLTPIPALQELAEEAGLKLEYASNFHSFYQERKDPAKFPAAHNALYNMKVLNRNGSVSEQEWNVSRMYVAIKFRKVGESSIHIGDEDVGEDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBP2</accession>
    <name>A0AAD9DBP2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">MEI2-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_009662</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBP2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12531">
        <property type="entry name" value="RRM3_MEI2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034454">
        <property type="entry name" value="MEI2-like_RRM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007201">
        <property type="entry name" value="Mei2-like_Rrm_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23189">
        <property type="entry name" value="RNA RECOGNITION MOTIF-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04059">
        <property type="entry name" value="RRM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="748"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="1102"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="220"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="375"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="483"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="856"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1020"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="57"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="105"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="403"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="483"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="515"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="535"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="583"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="638"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="872"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1034"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1045"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="1067"/>
            <end position="1077"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1739903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1229" mass="131222" checksum="F13D583D11CAC773" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBU6</accession>
    <name>A0AAD9DBU6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4395 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009229</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBU6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031397">
        <property type="term" value="P:negative regulation of protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030178">
        <property type="term" value="P:negative regulation of Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025508">
        <property type="entry name" value="DUF4395"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46472">
        <property type="entry name" value="NUCLEOREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46472:SF1">
        <property type="entry name" value="NUCLEOREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14340">
        <property type="entry name" value="DUF4395"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13905">
        <property type="entry name" value="Thioredoxin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="330"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="19"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="375" mass="42415" checksum="1213865625819CB0" modified="2024-05-29" version="1">MSTKVNPNDATKTDDWRLKLFGDELRMNTMTKMKRGDIEQALQEVSFASIPDAFDGYEYLALFFGANYCPFCKEFAPTVVAAAPAFAAKKTKVIFVSNDRDDLNYEESCEKVQGIDVMGYDLSKTAQMRDLFGLKTIPALIILQNKDFEKDEPFVVSNAREILELDPNLKRFPWGSIEKRQAAPLTAWDRLFIHGIHGNWWQLGHKNVSPLHPNQMYMDEHAVRIRAGLLNVITWVAIMNVFYMRNLLLVNVIFGIVSWEFVTSMLFGLTPFAPLGIIATLVAVVLQPSPLWKPANPKRFAWGVGLMLALSCFIIVQFKDEISEKDFKAAVAAIALTCNLFTWLESAAGFCVGCFVYNNVFVKYLGKEECKECKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCI0</accession>
    <name>A0AAD9DCI0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Putative GTP diphosphokinase RSH1, chloroplastic</fullName>
            <ecNumber evidence="2">2.7.6.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">RelA/SpoT homolog 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">ppGpp synthetase RSH1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_008823</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RelA/SpoT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.5" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCI0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008728">
        <property type="term" value="F:GTP diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015969">
        <property type="term" value="P:guanosine tetraphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04876">
        <property type="entry name" value="ACT_RelA-SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05399">
        <property type="entry name" value="NT_Rel-Spo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000002">
        <property type="entry name" value="GTP pyrophosphokinase (RelA/SpoT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3210.10:FF:000001">
        <property type="entry name" value="GTP pyrophosphokinase RelA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004811">
        <property type="entry name" value="RelA/Spo_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007685">
        <property type="entry name" value="RelA_SpoT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00691">
        <property type="entry name" value="spoT_relA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43061">
        <property type="entry name" value="GTP DIPHOSPHOKINASE RSH1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43061:SF1">
        <property type="entry name" value="GTP DIPHOSPHOKINASE RSH1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13291">
        <property type="entry name" value="ACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13328">
        <property type="entry name" value="HD_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04607">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00954">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HD" evidence="7">
        <location>
            <begin position="243"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="8">
        <location>
            <begin position="609"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00070102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00075768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00082153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1740728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1000" mass="112883" checksum="F2170096F6C12B55" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCJ8</accession>
    <name>A0AAD9DCJ8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome c oxidase assembly protein Cox19-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_008868</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the COX19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCJ8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010625">
        <property type="entry name" value="CHCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051383">
        <property type="entry name" value="COX19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21107">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21107:SF2">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06747">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHCH" evidence="5">
        <location>
            <begin position="26"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1740773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="111" mass="12964" checksum="E286024FED625CC2" modified="2024-05-29" version="1">MNFSSAKQTVKPPQRGIFPLDHDAECKPFKEKYLSCLKEGGDKHHLCRDFSKDYLQCRMDRNLMASEDLDRLGFSKEATVEKAVEYDKSKEKGGYVAGKHIDGRMKWWFQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCZ9</accession>
    <name>A0AAD9DCZ9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007716</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCZ9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="133" mass="14060" checksum="FD192E30E959E242" modified="2024-05-29" version="1">MTADKDFTFEPVPSNPPIVEAVPTPAPDFTASSNEDENPSDTAILVGCGLAGWVVGGPFLALLTALGGNWAKKKQGPFGESTRAVGRITAAAHKKARDEKLLHKMKSSVASLFGGRNSRCEHCDCEGQNVNLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DD22</accession>
    <name>A0AAD9DD22_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">SNF2/RAD54 helicase family protein</fullName>
            <ecNumber evidence="13">3.6.4.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_006454</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="13"/>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DD22"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004520">
        <property type="term" value="F:DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45766:SF3">
        <property type="entry name" value="DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45766">
        <property type="entry name" value="DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00641">
        <property type="entry name" value="Zn_ribbon_RanBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="57"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="374"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="10">
        <location>
            <begin position="666"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="589"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="707"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="758"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="589"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="758"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="776"/>
            <end position="785"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1742857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1137" mass="125844" checksum="6F318D287A7A56A7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DE30</accession>
    <name>A0AAD9DE30_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Beta-glucan synthesis-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_006291</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SKN1/KRE6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DE30"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015926">
        <property type="term" value="F:glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006078">
        <property type="term" value="P:(1-&gt;6)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005629">
        <property type="entry name" value="Skn1/Kre6/Sbg1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31361">
        <property type="entry name" value="BETA-GLUCAN SYNTHESIS-ASSOCIATED PROTEIN KRE6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31361:SF1">
        <property type="entry name" value="BETA-GLUCAN SYNTHESIS-ASSOCIATED PROTEIN KRE6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03935">
        <property type="entry name" value="SKN1_KRE6_Sbg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042167410" evidence="11">
        <location>
            <begin position="21"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="707"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="12">
        <location>
            <begin position="20"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="566"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="574"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1742694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="739" mass="81964" checksum="3F9B6E4B666A7F0F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DE73</accession>
    <name>A0AAD9DE73_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_007003</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DE73"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1742438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="132" mass="14375" checksum="9CFAC9D4D59185BD" modified="2024-05-29" version="1">MPTNKLSNCVPLSCLGGSSCCRVWKMTMQPVSTSSSSMLLSLLKEPSMVMVLLSLMLVTSTSMITNDYYDARNGVDVVSDDTDENGNILEEYGHYHPLAQGTVPFSVTKTFDSYLYAILLLSSAFVPGSISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEZ7</accession>
    <name>A0AAD9DEZ7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Prephenate dehydratase</fullName>
            <ecNumber evidence="12">4.2.1.51</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_004472</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.51" evidence="12"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEZ7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004664">
        <property type="term" value="F:prephenate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008977">
        <property type="term" value="F:prephenate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004665">
        <property type="term" value="F:prephenate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009094">
        <property type="term" value="P:L-phenylalanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006571">
        <property type="term" value="P:tyrosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04905">
        <property type="entry name" value="ACT_CM-PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13631">
        <property type="entry name" value="PBP2_Ct-PDT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001086">
        <property type="entry name" value="Preph_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018528">
        <property type="entry name" value="Preph_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003099">
        <property type="entry name" value="Prephen_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059064">
        <property type="entry name" value="TYRAAT2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21022">
        <property type="entry name" value="PREPHENATE DEHYDRATASE P PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21022:SF19">
        <property type="entry name" value="PREPHENATE DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00800">
        <property type="entry name" value="PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26213">
        <property type="entry name" value="TYRAAT1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51176">
        <property type="entry name" value="PDH_ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00858">
        <property type="entry name" value="PREPHENATE_DEHYDR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51171">
        <property type="entry name" value="PREPHENATE_DEHYDR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0584">Phenylalanine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042231704" evidence="9">
        <location>
            <begin position="30"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="domain" description="Prephenate dehydratase" evidence="10">
        <location>
            <begin position="110"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="Prephenate/arogenate dehydrogenase" evidence="11">
        <location>
            <begin position="465"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="64"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="747"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="692"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="756"/>
            <end position="767"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1745181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="767" mass="84495" checksum="4D3AE81E43EB2EFD" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DF26</accession>
    <name>A0AAD9DF26_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004158</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DF26"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="138" mass="15175" checksum="5EFA96D36323AF6D" modified="2024-05-29" version="1">MLEATRSEQSTERSGPQVKTWDPPSDEMLRREPALPPPGPLPLSFNEEGADSGVSNSEIAVGKFFDPGDDEEEKQEEDVSIADKWSEVTLDDSELGAYEHVVRCWKCRAGLKINIEIGLVVCPRCRSISPTTDVTNVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG43</accession>
    <name>A0AAD9DG43_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Thioredoxin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_004861</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DG43"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43601">
        <property type="entry name" value="THIOREDOXIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43601:SF32">
        <property type="entry name" value="THIOREDOXIN-LIKE 2-2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="157"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="32"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="43"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1744328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="300" mass="33534" checksum="12C381E683A2599D" modified="2024-05-29" version="1">MNNMNQHCATLQSSAIGAVCCKASTSSPVECEHKQLSPCRRNQNTRRRSHRRRGSNSSSRQFLFALCSIFSAACLLKQSQAFSSSSSSIHQSRISNAPSRFSLNGPTQQRHRANTRFYMSSVLEPASQSSSTRMSDFQRRMKGIVKRNGVANGRKVVGTSRSAPERPANLKVAHTLEEYKDQLDESSGKIVVVRFFATWCKACKAIQPSFYRMAALYPHITFVEVPVTNHNANLHQGLEVPSLPYGHIYYPDAGLVEEMKISKKYFPGLVKKVRWYDSGLCGLDEFVPEDSDDAAAEKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG51</accession>
    <name>A0AAD9DG51_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rab family small GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DG51"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01860">
        <property type="entry name" value="Rab5_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000808">
        <property type="entry name" value="Small GTP-binding protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47978">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="206" mass="22512" checksum="760225527BED17F8" modified="2024-05-29" version="1">MAEQSVKVVILGESGVGKSSLALRFVTDEFRPYSEATIGASFMSKSMTITPTNDEKEQKSTERNISFKIWDTAGQEKYRSLAPMYYRGSSAAILVYDIANPSTFAALQDWVTELNNNGPPGLVLAICGNKSDLEDDRMVGRSVGQEYAERINALFIETSAKDGSNVEDLFSQLARIIPPPINLNESLEEDVGLDLGEPVQSRSGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGS2</accession>
    <name>A0AAD9DGS2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FMR1-interacting protein 1 conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004354</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGS2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019496">
        <property type="entry name" value="NUFIP1_cons_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10453">
        <property type="entry name" value="NUFIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMR1-interacting protein 1 conserved" evidence="2">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="266" mass="29320" checksum="971BBA450B88EAD6" modified="2024-05-29" version="1">MSGHGIPPPPPPPPPRPGSSSGQKNDVGSLCPPPLQSSQYYHAGSQQQPMHHPHNPASYQMYQQYPGYSYNNAQYQHVQQQPVHSGYQYTQQNQQYYAYPNYASAPPPPPPPPPPRNPTTSTNTNIDNAVIPANTKSDTPSPNKATQSDKPKKVNPKMAQKYSGQGLKTITISGPGLRPQKFKICVGNHPDDIQKWIEERKKNFPRTSSRQKGTNDSNSNGRQHDIASKRNKEGKVENESDKQHKEAGKNAASLSNLLAGYGSSHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGV4</accession>
    <name>A0AAD9DGV4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001259</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGV4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041965951" evidence="2">
        <location>
            <begin position="22"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="384"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="411" mass="44664" checksum="B8F43D375828107D" modified="2024-05-29" version="1">MQLLTTLTLGAAGLQTALVSSFTSGPVAISPRFAFVSQHPYRNAVDSTYPLRTPLCVAAKTLVEESDEALLTPETYADSQSAESEVEHIIMDAAVEAFEATDFTTEPHLPPELENCEVIYADDGEEDESSSSLPTDSQTVSFQEALLAQQLAYNTKKSEPVVSEETQEVSKKQEAFQRSLLAARLSTDTAENSLLEAEEEFLQKDSQMNWMESEVRAASLGGKESLPFHDSAAMATRSADLADAENMAETTPTTFSATDQVAAAKRKIGVTPVIADWEVAKSAGKRSSKHPPADLEIQSYVTKRGVELTKERMRQKLGVSTDDNKETPSKSRGLVVRKLAAGTEDSVTTYLSAGEKSKVQTVLQSALEKLLHTGLVKRLSQPKILIFSLLLGVLCRSLALAWFGNPAMRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHZ4</accession>
    <name>A0AAD9DHZ4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHZ4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044624">
        <property type="entry name" value="Mbb1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44917">
        <property type="entry name" value="PROTEIN HIGH CHLOROPHYLL FLUORESCENT 107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44917:SF1">
        <property type="entry name" value="PROTEIN HIGH CHLOROPHYLL FLUORESCENT 107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="103"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="203" mass="23135" checksum="F7FC42B433ED6EEC" modified="2024-05-29" version="1">MGNLAAAEELYLQALRSRPSHAAAWVALAQLRTKELRQGAKAGRACYQSAERELQRIGAKPNAFVYTAWASMEYKKGKEDDVKSVRKSRELYRKALEADPRCSAAYLQLGVMESECGNFDTAKECFEKVLTFDQRNSRVLQAYAIMESRRPRDEVNSRRVLDLFERALRVNPRDAGVYQAYALYVVELGDMTQPEISLKEELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIA8</accession>
    <name>A0AAD9DIA8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WD repeat G protein beta family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_002149</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat G protein beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIA8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016346">
        <property type="entry name" value="G-protein_beta_1-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001632">
        <property type="entry name" value="WD40_G-protein_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19850">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25391">
        <property type="entry name" value="WD40_Gbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002394">
        <property type="entry name" value="GN-bd_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00319">
        <property type="entry name" value="GPROTEINB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0807">Transducer</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="56"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="145"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="186"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="229"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="318"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1746805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="350" mass="38232" checksum="D19837801037988B" modified="2024-05-29" version="1">MSEEERIEAAEAEVASLKEQIEQVRASKQKNTMGAVAASKGPLREIRKPIKMRRTLKGHFGKVYAMHWASDSQSLVSASQDGKLIIWNAYTTNKTNAIPLRSSWVMTCAFEQSKGNLIACGGLDNVCSIYNIQNQGANARATKELVAHDGYLSCCRFTDEGHIITSSGDSTCIYWDITSGEVLKAFSDHTGDVMSVAINPENSNVFVSGSVDKTAKIWDLRNGKCVQTHVGHENDINSVTFFPDGNAFGTGSDDSTCRLFDMRSYGEVNKFGNDKITSGITSVAFSRSGRLMFGGYDDYSTYVWDTLADASQVAYALPSQHENRVSCLGVNAKGDALCTGSWDTNLKIWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJN6</accession>
    <name>A0AAD9DJN6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000558</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJN6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="647" mass="72197" checksum="9BF9007FD1029965" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJP0</accession>
    <name>A0AAD9DJP0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Beta-1,4-galactosyltransferase</fullName>
            <ecNumber evidence="14">2.4.1.274</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_000139</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.274" evidence="14"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJP0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008489">
        <property type="term" value="F:UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008728">
        <property type="entry name" value="Elongator_complex_protein_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003859">
        <property type="entry name" value="Galactosyl_T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027791">
        <property type="entry name" value="Galactosyl_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027995">
        <property type="entry name" value="Galactosyl_T_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19300">
        <property type="entry name" value="BETA-1,4-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19300:SF57">
        <property type="entry name" value="BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02709">
        <property type="entry name" value="Glyco_transf_7C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13733">
        <property type="entry name" value="Glyco_transf_7N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05625">
        <property type="entry name" value="PAXNEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02050">
        <property type="entry name" value="B14GALTRFASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Galactosyltransferase N-terminal" evidence="13">
        <location>
            <begin position="4"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="Galactosyltransferase C-terminal" evidence="12">
        <location>
            <begin position="84"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="361"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="562"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="386"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1748200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="598" mass="67797" checksum="B5A1B788769E5094" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DK87</accession>
    <name>A0AAD9DK87_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000784</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DK87"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46210">
        <property type="entry name" value="FHA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46210:SF1">
        <property type="entry name" value="FHA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="339" mass="37307" checksum="56C596FE05C7AC0E" modified="2024-05-29" version="1">MLGRSSGSDMVLDYRTVSARHASIRFKNGEFLFTDAGSSNGSYLYLRRPVELNSNQSVQFRLGRSMISMKVVNKWNRRLLRAVSRRAGIGNSSSNGGGEEGGDEPSVGSNEDDVRVTDNSGSVTRTLPRRTRENIMESMPALGTLSQNSTQHLDLLYALAYPKKMEKEVPKRAKPVALNTALLPSPPMEQLSETPEENDGDESKADDEDVVEESEDQDDVEELFDEIADQVNEMVLEEENEAEDVEDTNINQNLNDQIDICGAEAEAAEETDDAQEDNAGEQEQHAAVSVDEAAKNKRIPLSGHLAFSYKNEGGIGLKMLSGRVDKIVVVWLNIESGSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DKE5</accession>
    <name>A0AAD9DKE5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 11">Mitogen-activated protein kinase</fullName>
            <ecNumber evidence="2 11">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_000964</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="11">Activated by threonine and tyrosine phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="2 11"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DKE5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07834">
        <property type="entry name" value="STKc_MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000013">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000028">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 11 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5 11 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="40"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1749025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="399" mass="46148" checksum="9B23D8F31D32BD1C" modified="2024-05-29" version="1">MAPSLPSMEWRSCQDVPERHSLQCSYLQAGDNTFTVDSRYNFTRVVGSGAYGVVISAQDTHLNSRVAIKMVPKAFQDEIDAKRILREIKLLKHLKHDNIVGIVDMMPPMTRYVDDFHDVYIVSELMETDLYRIIYSKQSLSIDHVKYFTYQILRALKYIHSANVLHRDLKPSNLLVNSNCDLKICDFGLARGVLDDSQMKDQSKRPLLTEYVVTRWYRAPEIMLACHEYDKPVDVWSTGCILAELLARKPYFPGDDYIDQLNLITSKLGKLPDKDLEFVTSEKARRFMRKLPNNKVVPLSKQFPNAPPECIDLLRQMLQIHPSKRITVEEALKHPFMAQLHTEEDEPVCEAPFDYSFEDEKLHRIRLQELIWEEVGDFRPQCLPAAPRRDGTRPPTVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DKM9</accession>
    <name>A0AAD9DKM9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000827</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DKM9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042092106" evidence="2">
        <location>
            <begin position="28"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="114"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="181" mass="19551" checksum="7097EEDCEBEDF8CA" modified="2024-05-29" version="1">MMQPRRISRTILLVTILAIYGSRPLSAIDLGRFGTKNADNNKNADKEDAIEDARRLLNSMNDAATGTVTSYQPGGGPKKAEVVTCDEIMAKSLVVANEEKAAVIAEKTAVVKAASLLSDRIDELSEKLKEADDRIAAAEVAFSDLEQTTQSKLDAAAKEADERIKEANDAAAEEIERMKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2KZK9</accession>
    <name>A0A7S2KZK9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">rRNA-processing FCF1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_006541</name>
        <name evidence="8" type="ORF">SMAR0320_LOCUS6581</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the UTP23/FCF1 family. FCF1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="HBGZ01009169">
        <property type="protein sequence ID" value="CAD9589914.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S2KZK9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09864">
        <property type="entry name" value="PIN_Fcf1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1010:FF:000004">
        <property type="entry name" value="rRNA-processing protein FCF1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006984">
        <property type="entry name" value="Fcf1/UTP23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037503">
        <property type="entry name" value="Fcf1_PIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12416">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN UTP23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04900">
        <property type="entry name" value="Fcf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="PIN" evidence="7">
        <location>
            <begin position="64"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CAD9589914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1742944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="194" mass="22253" checksum="F5103B57AA4132D1" modified="2021-06-02" version="1">MGKAKKTRKFAVAKKIISPKDARVKSNQKQQKALAESKKEKPRHVDQAISALFFQYNTQLGPPYHVLIDTNFINFSIRNKMDIVRSMMDCLLAKCIPCITDCVMGELEKLGSKYKVALKLAQDPRFERIPCQCRGCYADDCLVNMVKQWRCFIVATCDKELRGRIRKIPGVPCMYISSHRYTVERMPEAFGAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XR85</accession>
    <name>A0AAD8XR85_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016969</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000072">
        <property type="protein sequence ID" value="KAK1732339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XR85"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041988511" evidence="2">
        <location>
            <begin position="22"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="301" mass="33555" checksum="0822B2E0565F96A8" modified="2024-05-29" version="1">MIWLHHLFILSVATSTPQATAAFINSRRGTNANPNNQQIQQQQQTAVVSTAADAALAINSIKFMNTLCGRKNTADVRTFTQSITSSMGNTNNVHVQTKNDSCIEKQNASRDDDDETQWTLLNVFFRNEEQQDCPEIISPKTTDPSSSSLHNKSNTSLPQSTSTHETVAEYIGKLWFLPKDKGTIKFRETIRIISLGLDGETSTVECHTQYYNGSEWVDCSKVLCHFTSLSTNYQQVRTDITNDDDDAASTASLQQKVKMTLDCELLVWLPLPSVASKAVRKKISSVFEEIVAEFFDELAMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRY2</accession>
    <name>A0AAD8XRY2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016573</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000059">
        <property type="protein sequence ID" value="KAK1732726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRY2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="231" mass="25760" checksum="144E934BF8DF83BB" modified="2024-05-29" version="1" fragment="single">MVTRILTLVRVRTAPAAIAGQCSSSTQNTHNQNYRRLFNDDEKIILPAAAASAVEAKKEDDKPGDLNRGDSQLREAEATHHAASQRKRQCSESEGEDVVPKKTARKKHRKLCSTDGCKSKSQRGAVVKDAQINLIEEECAPDMEQRWNYAAAKDARVLLETEECVLNLGQRKSYAVAMDAQVKLKREACVGDMGQRGSFAALKDARAILEQEESVTCMQRSNDRRYDYENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XS91</accession>
    <name>A0AAD8XS91_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016429</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XS91"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="297" mass="32852" checksum="EAEE0C8F7D9C7404" modified="2024-05-29" version="1">MMMEEEGGDNASSNSCPATDSTMATPTDDFEALLSVPIEIIFREIMQTQIISGGKRTNQRTFLFSKSEVTTLLRVSVLASELTTTIAMVYEALDRARKGNMYRHEIIEATHNNNGYLRALLPIIAIHTETAQDALTNVTSDTNFGISRILQELDDCAMELSKFSETNFNMADQLDWTMTAGQCSVLSKEKRAIAEIEEAVVARITCLKEMAIGGTTKDEEEVETSTNNDVIDTTSSGDDAASNYNHRDDRFTPMRDLCHKIFKEKEKAEFNLNTSSSEHSQSQITAAEAMASLAKEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XT11</accession>
    <name>A0AAD8XT11_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016313</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000055">
        <property type="protein sequence ID" value="KAK1732982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XT11"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="150"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="229"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="369"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="595"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="193"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="252"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="369"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="793" mass="87187" checksum="7A9B89925EA1E3B1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XT42</accession>
    <name>A0AAD8XT42_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_016089</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000052">
        <property type="protein sequence ID" value="KAK1733232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XT42"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="296" mass="32649" checksum="086669D14B85127D" modified="2024-05-29" version="1">MMAVDEYYIFTGGVVPRHVTRVRIDESVTVIPAQAFKGHPNITEVVFHDGVKKVKDEAFSYCRSLRLVIMPGVEVVGAEAFWGCDALTDVECGKLEIIGVCAFGICDSLRSINLPSIKIVEIRAFSGCDALTNVKFGKELESIGSSAFYGCMSLERITIPLKDGMINDNDIFQGCEDMKHVDLVEGAILHETINALLLEEWKNDMNEEIASINQILPTAPAGSVYPDDDDDVGRKAEAIRAWITNVLLNIVQYKAQHQSYVNEASTTLQLALPSDIVIKSVLPFLKLPSYTFQGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XU79</accession>
    <name>A0AAD8XU79_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RAP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015738</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000047">
        <property type="protein sequence ID" value="KAK1733565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XU79"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035770">
        <property type="term" value="C:ribonucleoprotein granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000963">
        <property type="term" value="P:mitochondrial RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044528">
        <property type="term" value="P:regulation of mitochondrial mRNA stability"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011632">
        <property type="entry name" value="DUF1601"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050870">
        <property type="entry name" value="FAST_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013584">
        <property type="entry name" value="RAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21228">
        <property type="entry name" value="FAST LEU-RICH DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21228:SF40">
        <property type="entry name" value="LD45607P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07671">
        <property type="entry name" value="DUF1601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08373">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00952">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51286">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RAP" evidence="1">
        <location>
            <begin position="787"/>
            <end position="866"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="869" mass="96354" checksum="FF47F70D513E82FA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XU92</accession>
    <name>A0AAD8XU92_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ubiquitin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015359</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XU92"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01763">
        <property type="entry name" value="Ubl_SUMO_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10562">
        <property type="entry name" value="SMALL UBIQUITIN-RELATED MODIFIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="488" mass="55397" checksum="EB9DB70D35EA8461" modified="2024-05-29" version="1">MSGCGSTTVSSAEVINRVLIDIRDIKSGEIECTFRLPRSLKLGRVYDAFQGIRGGEDSFILKLDGRKVAWVDTPTSLGMSDHVELSCVPAVKVVIRNFWTQKIDCSFVIESNDTFRLIHQACVKKRGNAGFDLSFHGRKVKLSDSPSSLGMKNHVELTCVPVPVVTIVIKDTERPGNVHKFLVRRDQKLSKIYLKYRKMKGDGSFFFMHNGYKIISLNETPDSLGMKDQVEISCVSRSSVIIDIFNVETQEVDWTGTLESSASFKHIFMECDRLQYKSKSRSSFYLESSSLEFNGSRISDDDTPHSLGMGDSNRVEVSYTPNPVVEIDVYKHGDFVRTFRLKPHQPLRTIYNRYSDEVLCLTFNGSKVPPEATPDSLGMKGLQHTEMILEPYAIISICNCMTPQDIVSFELGRKATFRILLDTYKEQEGYKRSFDFYFKGVIIDLDKDTPESLGMNDREEVACVPQFNKKTPKEECPCINWTELVFWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUC8</accession>
    <name>A0AAD8XUC8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015319</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1734061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="62"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="720"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="899"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1237"/>
            <end position="1257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1312"/>
            <end position="1337"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="284"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1043"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1183"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="118"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="182"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="196"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="741"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="899"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="912"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1239"/>
            <end position="1257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1312"/>
            <end position="1324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1354" mass="151900" checksum="88EB55B7106B6C77" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUL0</accession>
    <name>A0AAD8XUL0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_015255</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1733997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUL0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023779">
        <property type="entry name" value="Chromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF15">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00598">
        <property type="entry name" value="CHROMO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="4">
        <location>
            <begin position="6"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="144"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="153"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="183"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1733997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="707" mass="79605" checksum="18802E808C911E4C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV23</accession>
    <name>A0AAD8XV23_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pseudouridine synthase, RluE family</fullName>
            <ecNumber evidence="6">5.4.99.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_015472</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV23"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050343">
        <property type="entry name" value="RsuA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47683">
        <property type="entry name" value="PSEUDOURIDINE SYNTHASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47683:SF2">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="5">
        <location>
            <begin position="215"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="129"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="179"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="134"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="179"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1733945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="338" mass="37601" checksum="4F528F4FC3C718EC" modified="2024-05-29" version="1">MNDDDAISSSALSPNNATTTHHRHFKMYKPAKVLTQFKFTHRKRRNRTLLGDVITAADTTLLPSNGVMAIGRLDEDSEGLLLLTTDGKVSEQVRRKSVEKEYYVQLDGKITQEAIERLQLGVEISLPATNNHKHRDDDGDERSSTCESTLPSPPASTTTSYTTMPCKARFLDTSIITVENKKNEATTKEEDHSNQPSETETKPNKRKRRKFGGTCNRCKQAGHKAKDCTDNPVDLFNTNNNCNNNNDNVVQLALPAGIIPPPPSRNGYYNIRNTTSRPTSWISITINEGKNRQVRRMTAAVGYPTLRLVRVKIGCVGLDGMVAGEVRELSEDVMDSII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVC3</accession>
    <name>A0AAD8XVC3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4239 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015353</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1734095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVC3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025333">
        <property type="entry name" value="DUF4239"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14023">
        <property type="entry name" value="Bestrophin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="402" mass="44696" checksum="2D2242D905149002" modified="2024-05-29" version="1">MKTEYPKIVTFSLQPFCRQFSPFYYGGKISIGLSVFLSSFGVVNSAEGIVFTDNLLRPTIIGVVVPVISIALATLVSTTVNVLRQRQVDLRAFINEEAGELRFLRRAIFGMYGTRQHAGRRARALVLLRGYVEQLMTECDDGAVGRLEEMQLSGGIADNELDRFAAMLHGVDGAAASRQGSVEAAEELIRSLNSHRSKRVALLLTDFPVLHWDILAGLNVSILIAFLLTSNQPTLQYLSSIQLRFLFATIVAVCSGTATLCWDLDNPFSGSFSIAGASTQLADMRVCLREDIREALVESDEIPSDTRKFFRSQFGGPSVSASRELSEEDEELDPSSRYGLLPTLYWHLLTGPAGAYVRMFGDAAAWLTTIVGRKLQTIILHRGRRVRLIIKRWWRSFEFESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVP4</accession>
    <name>A0AAD8XVP4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015194</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVP4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24178:SF9">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24178">
        <property type="entry name" value="MOLTING PROTEIN MLT-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="283" mass="31280" checksum="43F71E77A6A11C8B" modified="2024-05-29" version="1">MADDDDGKLPLHYVLWNENVTLKMVQLLIDAAPESIMHQDNDGSMPIHRLCCNYDLEEEEALKTLKFLVDKSPQSARHADEDGDLPIHIACLEPRSPEFCRFLIESYPGSERIVNNSGMLPLHLACQSSTVATAEYFLNIFQAGIAMTSDCGYPIHCAIAGLCDRGNDASTAAKMVELLLARDPDIASQTYAGSTPLEWALLQEYDTNLHIGLRVIHLLYDAYPEAATAFDPLLMHNAISNEIISEEILRCLVVFVPRAAGGTDDDGQHPFTLHAITTMSHSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWM6</accession>
    <name>A0AAD8XWM6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013878</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="254"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="862"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="987"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1110"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1371"/>
            <end position="1390"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1193"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="48"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="285"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="300"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="987"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1027"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1123"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1371"/>
            <end position="1381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1474" mass="167698" checksum="C00F417B0CDAD64A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXK1</accession>
    <name>A0AAD8XXK1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013447</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXK1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052420">
        <property type="entry name" value="Espin/Espin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153">
        <property type="entry name" value="ESPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153:SF8">
        <property type="entry name" value="FORKED, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="230" mass="24945" checksum="35C14FBD38863047" modified="2024-05-29" version="1">MISFEVLDFVSYLLGLIEAREWETFRSCALEPSPTHFRARTNVIAQIPEFNGMTMLHAALKCDPPQQLVLDMIEICPDLLAARDCLGRTPLHVAAGSAADPRLIKILAHVCPPACDVQDVDGKTPLHFACDSSSVLFQDDHNNKSATLRAPCHDAICALLSESLAAATIEDADEMNPLEHAIMSNASLKTVKLLQNAAANYLQRASMSMCPGPTTMSLRRVSKANNDTSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XY48</accession>
    <name>A0AAD8XY48_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histone acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="26" type="ORF">QTG54_013548</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="26" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="26">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Acetyltransferase enzyme. Acetylates histones, giving a specific tag for transcriptional activation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:45948"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="26">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000123">
        <property type="term" value="C:histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140297">
        <property type="term" value="F:DNA-binding transcription factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15614">
        <property type="entry name" value="PHD_HAC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.20">
        <property type="entry name" value="Coactivator CBP, KIX domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1020.10">
        <property type="entry name" value="TAZ domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031162">
        <property type="entry name" value="CBP_P300_HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013178">
        <property type="entry name" value="Histone_AcTrfase_Rtt109/CBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036529">
        <property type="entry name" value="KIX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036546">
        <property type="entry name" value="MED15_KIX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038547">
        <property type="entry name" value="RING_CBP-p300_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035898">
        <property type="entry name" value="TAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000197">
        <property type="entry name" value="Znf_TAZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13808">
        <property type="entry name" value="CBP/P300-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13808:SF1">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08214">
        <property type="entry name" value="HAT_KAT11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16987">
        <property type="entry name" value="KIX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02135">
        <property type="entry name" value="zf-TAZ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00569">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01250">
        <property type="entry name" value="KAT11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00551">
        <property type="entry name" value="ZnF_TAZ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57933">
        <property type="entry name" value="TAZ domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51727">
        <property type="entry name" value="CBP_P300_HAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50134">
        <property type="entry name" value="ZF_TAZ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01357">
        <property type="entry name" value="ZF_ZZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-0010">Activator</keyword>
    <keyword evidence="15 26" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="11 17" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="9" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="19" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0804">Transcription</keyword>
    <keyword evidence="10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5 26" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 18" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TAZ-type" evidence="23">
        <location>
            <begin position="402"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="21">
        <location>
            <begin position="584"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="22">
        <location>
            <begin position="732"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="domain" description="CBP/p300-type HAT" evidence="25">
        <location>
            <begin position="824"/>
            <end position="1482"/>
        </location>
    </feature>
    <feature type="domain" description="ZZ-type" evidence="24">
        <location>
            <begin position="1484"/>
            <end position="1537"/>
        </location>
    </feature>
    <feature type="domain" description="TAZ-type" evidence="23">
        <location>
            <begin position="2178"/>
            <end position="2257"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="21">
        <location>
            <begin position="2362"/>
            <end position="2434"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="22">
        <location>
            <begin position="2510"/>
            <end position="2586"/>
        </location>
    </feature>
    <feature type="domain" description="CBP/p300-type HAT" evidence="25">
        <location>
            <begin position="2600"/>
            <end position="3089"/>
        </location>
    </feature>
    <feature type="domain" description="ZZ-type" evidence="24">
        <location>
            <begin position="3091"/>
            <end position="3146"/>
        </location>
    </feature>
    <feature type="domain" description="TAZ-type" evidence="23">
        <location>
            <begin position="3157"/>
            <end position="3238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
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            <begin position="55"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
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            <begin position="470"/>
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    <feature type="region of interest" description="Disordered" evidence="20">
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    <feature type="region of interest" description="Disordered" evidence="20">
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        </location>
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    <feature type="region of interest" description="Disordered" evidence="20">
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        </location>
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    <feature type="region of interest" description="Disordered" evidence="20">
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            <begin position="1911"/>
            <end position="2003"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="2816"/>
            <end position="2845"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="2918"/>
            <end position="3034"/>
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        <location>
            <begin position="2434"/>
            <end position="2461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="55"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="81"/>
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    <feature type="compositionally biased region" description="Low complexity" evidence="20">
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    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
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    <feature type="compositionally biased region" description="Pro residues" evidence="20">
        <location>
            <begin position="153"/>
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        <location>
            <begin position="350"/>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
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    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="1789"/>
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        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="1802"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="1933"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="1956"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="20">
        <location>
            <begin position="2824"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="2922"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="2961"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="2996"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS50134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="PROSITE" id="PS51727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="KAK1735842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="3271" mass="365871" checksum="AA7B3AF13FE78925" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYT7</accession>
    <name>A0AAD8XYT7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="6">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_013106</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="6">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1735970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYT7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="130"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="425"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="588"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1735970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="655" mass="71758" checksum="1218671063F68D0E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZE0</accession>
    <name>A0AAD8XZE0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_012863</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CHAT" evidence="4">
        <location>
            <begin position="968"/>
            <end position="1103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1736263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1435" mass="158627" checksum="CCA079FA0098C3D3" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZP5</accession>
    <name>A0AAD8XZP5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012998</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZP5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1736398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="230" mass="25780" checksum="955766F9C8960BAB" modified="2024-05-29" version="1">MSFHLQAWSYKYKWGCYHPERTFDSGFSNTIEGFDNNQGKVVWRKAGFSFDEDLQPQQNLTFGVFGPDLLDGPGGVFFGLIKDTDKWIRPSFLGQTGYKSFCAPVVHYIAKAAGFIVNGLPLKLDDRTPTYVIFDTGLSGMAVSDELYQGRNLQARKNREKSLWGEVKVSFQTKAGDEVELSARKPITTPLGQDTPWTKFKGNLIVLGLAFLDGTSMSIDIDDNKLQLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZP7</accession>
    <name>A0AAD8XZP7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Bestrophin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_012755</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZP7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044669">
        <property type="entry name" value="YneE/VCCN1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281">
        <property type="entry name" value="UPF0187 PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281:SF19">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION CHANNEL-FORMING PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25539">
        <property type="entry name" value="Bestrophin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042014766" evidence="9">
        <location>
            <begin position="22"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="30"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="30"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1736733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="436" mass="48789" checksum="D69B7067C6254261" modified="2024-05-29" version="1">MLFRCMAAFAVLAAAAPTCEAFSTNPTPLAIKPSTSSQQRTNKSALFMGPPTDPSAPATDLYGEGSRKYRRTVYTHDQWVKHRSPDRFVNNLSTLFNSGIYKNVGKEVVFTTSVAIFVWAWNLLVGGYQDLSGVAHDPIIQGEWAKIVGLPLQAFTTVSPSLGLLLAFRTNSSYKRWDEARKFWGLNINHTRDLNRMATAWYGNEGDPWDGTEFMGAPSSKAQAIDPAERQYLLGQISLMTWAFVRSMKRHLSPPDEDEEDYIAEMKSRLSPEQAEAIISAVHRPNRALYDLSVAIEKLPMHFLRKDELNKNLSIFEDTLGGCERLLSSPIPLFYSRHTARFLSTWLLLLPFALYGQFGDSWNHIMMIPATAFISVSLFGIEELATQLEEPFTILPMQGFCDKIGGWCDEITSWAGQGQEAEEAVQANIAEIAPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y068</accession>
    <name>A0AAD8Y068_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012003</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y068"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="141" mass="15840" checksum="995B4985A7632A0A" modified="2024-05-29" version="1">MALVLPGDEQLVTPFTFYTMSQCRPCNLDIKGNGSRSNFEHGFPGLECIHCAGPSSRKFFYRSADILAGNYAHIPNHLLSCAAAPASLKTTLTELKQRHQTQKHHLHKGDQKSFFQNIWNRLHQESNEDETMGEVGQVAEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0T5</accession>
    <name>A0AAD8Y0T5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helicase-associated domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012179</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0T5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.530">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005114">
        <property type="entry name" value="Helicase_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33418">
        <property type="entry name" value="HELICASE-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33418:SF1">
        <property type="entry name" value="HELICASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03457">
        <property type="entry name" value="HA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase-associated" evidence="2">
        <location>
            <begin position="408"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase-associated" evidence="2">
        <location>
            <begin position="509"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="110"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="604" mass="66691" checksum="F1EB498BEF9A1615" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y120</accession>
    <name>A0AAD8Y120_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TLC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_012060</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y120"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050846">
        <property type="entry name" value="TLCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439">
        <property type="entry name" value="CT120 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439:SF0">
        <property type="entry name" value="TOPOISOMERASE I DAMAGE AFFECTED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="7">
        <location>
            <begin position="71"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1737193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="286" mass="32208" checksum="0D7B55EFAD3B68EE" modified="2024-05-29" version="1">MIPSPVFVKYDSALFDAIHRDVPTFLPQEDHKEAITWILSIAGAITLFHLVLLQMVKVWQGSKETTHATWKASYQLTNLLVNLILGCVGIYYQLFKIKSDEAILDRIVGNEHMMLFSAGQVGYQLWALPIGIIFVGETKSMIIHHVAVICVGSVTAFISSGFRYFTPYFYGVIEISSVPLSVMNSFKNNPDWIEKYPGAYKNVRLVFGITFLLVRVILWTPIYWNFVSLASMLLYSSDVVSTQIILSIFILASLVLTILQYFWASKIVGALVKGGPKKKKQAKKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1S9</accession>
    <name>A0AAD8Y1S9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011756</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1S9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="334" mass="38907" checksum="D377BA8E47BB1A08" modified="2024-05-29" version="1">MTTKITDHCGQITSLTRVIILVILAILLGCNYRQFTNFTILTSSLSSSILQQMQTWDFGNAIAALVAVGGYMAEHLFSRKQAQMEKQMERVEAQSHQLLVPVTMQLHRLWHGCIMNFIDKHCEDILLKKDEYKETLIKCTNSMERWGEGSDAFHLELPTRYRHAVSFPWALEVMHEDYNIMRVTHPRELPLILHDEILKCDRNSTLWKSYEAFIRYSYLPAIERIGEIIDEHGHLMEPVPAARMKEIFKTEGNGYGIKWSHAPRMWFYSHMLAYVDSWKELLSKWNDGSYEEIRPSIDFPVGLLRFNIEMQQIVAKVEQNLIGTSQLYGHANRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3H2</accession>
    <name>A0AAD8Y3H2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3H2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="443" mass="48637" checksum="5167B09879922E0F" modified="2024-05-29" version="1">MMNARMRRRLKRRGKTVDQQDAGDDDDKVSVSSPPRLRRDSTNNISSSTREFTFNLEEAGAPIIDTTNDFGGGTISTVTNDVAFRDKAFRCGFDSAEYTVMQQQQSQLLTKKDETTCLQLQTDGDEFRSSKGASTKKTQESPMGVNEFDFPDQQFEWADFDSNNKGSNAKQGPSSAKLNLGRNLKKDDDSFFYSASAPSSEGTNDTKLVGETITLGSTSSYLHSCDILDNGRKAETEQGSRRVDTHQLGMGRGSPIRQPSPRDSSLTCQTKEVHTAVAAAAAAPPPPPPPQAPRQRSKNPKEDVSNNDDSTKPGCAVPDIVQEFVDDVKSVLSQVISVAYLACSEGEQCLSRCQSDEPETYQLNTIVEDSTVPLPNPPSVVRGGDESKRFKKPWAGDYLCHRTGTEETADNSSQEAEGTAVKKQGSRTNRLRKFLTSFKTRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3H7</accession>
    <name>A0AAD8Y3H7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Myo-inositol 2-dehydrogenase</fullName>
            <ecNumber evidence="5">1.1.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_011385</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfo/Idh/MocA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.18" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3H7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050112">
        <property type="term" value="F:inositol 2-dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055170">
        <property type="entry name" value="GFO_IDH_MocA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840:SF3">
        <property type="entry name" value="BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G10240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22725">
        <property type="entry name" value="GFO_IDH_MocA_C3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="17"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="GFO/IDH/MocA-like oxidoreductase" evidence="4">
        <location>
            <begin position="147"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1738091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="348" mass="38250" checksum="4CAC654D15D7AF48" modified="2024-05-29" version="1">MTTFRSTSMLLRQAQARVLVVGSGRMGHIRTKALYGNPRIQLCGIVDTNIEQAKSLSELYRTPLFASLEEAISSTATTQLPLDGVVISTPTPTHESLIIEAAQNNLSIFTEKPVDETAHNTSSLFQTCNNQNVNLCCGYQRRFDSSYQALFHQVNSGAIGTPLAASIFFGDHPVPSRQFLLQGGANIISDCSAHDVDFIRWVLQDEVVSVYAVGTSSDDELREKNVIDNATMLLKFSRGTNVTLTLSRGANYGYDQRCEVFGTEGMATVNNIAENSSELANESGLHRPKWQHSFPQRFEAAFAQEMDAFADTLLGGTPWPIKEEDCVEVQRVCDAALESCETSQVVHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3T5</accession>
    <name>A0AAD8Y3T5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase</fullName>
            <ecNumber evidence="2">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010278</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3T5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050744">
        <property type="entry name" value="AI-2_Isomerase_LsrG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33336:SF1">
        <property type="entry name" value="(4S)-4-HYDROXY-5-PHOSPHONOOXYPENTANE-2,3-DIONE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33336">
        <property type="entry name" value="QUINOL MONOOXYGENASE YGIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51725">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="62"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="188" mass="21111" checksum="CDD84D9916F55F35" modified="2024-05-29" version="1">MWRAASAISSRCAHRCAAQPIIFANNVGPSISRRGTNAAAAAKHTSSHLRTFSSQSNQADYLCVHVFVSVKPGTEEDFMLASLENARASSLEEGIARFDVIQQEDDPSKFVLVEVYKNADAPAAHKGTNHYAQWRKTVEHMMAEPRKAIKYKICFQRLVMDGIMVLMLIWNERGFWCEIRPLLLLMGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3X0</accession>
    <name>A0AAD8Y3X0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rossmann-fold NAD(P)-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009764</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3X0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051207">
        <property type="entry name" value="ComplexI_NDUFA9_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126:SF16">
        <property type="entry name" value="MIOREX COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042034573" evidence="1">
        <location>
            <begin position="21"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="NAD(P)-binding" evidence="2">
        <location>
            <begin position="98"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="303" mass="30872" checksum="72BC18280D6CBD15" modified="2024-05-29" version="1">MKIACFLLAATLAAIPQCSAFSTNSVLPTRRHVSAPSSLQLKADEQYDGDDRHSPKCELSRRTALSTTFAIIATTASPFLHPIVSNAQDSKGKVVVYGGSGYVGAHACSLLTQQGYAVTSISRSSPETQLARSKSILGTSLSNVDYISLDAGKASLDDLSASMKDATAVISCVGLSPGSQNQKDGNGLVNSRITQAAKAAGVPKIVYIGVSSTLANGPAKFLLGDYFAGKATAEKSVTSEFGGKNSLIIKPAIIAGGPPGEIRPPGPPGVKAVDVTAVARAAVSGAVGDLIGVIDGNEAIEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4Q5</accession>
    <name>A0AAD8Y4Q5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4Q5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21383">
        <property type="entry name" value="GAT_GGA_Tom1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89009">
        <property type="entry name" value="GAT-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="207"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="257" mass="27021" checksum="A102447087DF71F6" modified="2024-05-29" version="1">MWSYLQKCFLCYCREQKLHKDPIILIPASCSLYNTMQSTHHSTSSGTQTAAASSNPDQKVLTDLGTLTDQINLCQSMLAQSGSSIDGDEALLQVIGFLEACVPRMVELIEAAAQGALTPETFEECLVVNDKLANILSDVEKEPKDRQPIVPAASAKAVVGSSELDHVEEDMDNLGIGGGSTTLPLAAVAGGKTTGLDDAEDPFSGGPDLLSPTPLSSDLFSTTTTSAAASAAPKSNDDDDFDAFFRDRTSAGGGKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5Q1</accession>
    <name>A0AAD8Y5Q1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_008932</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1739982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5Q1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="17"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1739982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="283" mass="31713" checksum="1665DABDA8EBA347" modified="2024-05-29" version="1">MMSGVSDEDESDNMICCAACGVAENENIRLKKCNACKSVRYCSVQCQKDHMPQHKRACKKLVAELRDEILFKQPESTHLGDCPICCLPLPIDDDKYIMMACCSKMICNGCNYANRMRELEGTAKSQKEAERDLMKRAEANDPVYMSQVGVRCYQEGDYKGAFGYLTKAAGLGDAVAHFQLSCMYYDGKGVQKDKKKEVYHVEQAAIRGHLRARHNLGFIEKAVKHWIIAANMGYDGPLENLKLEYREGLVSKEDYASALRGHQTAVDAAKSSQRDEAEAARIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y699</accession>
    <name>A0AAD8Y699_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053337">
        <property type="entry name" value="AT-2_adhesin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37001">
        <property type="entry name" value="PHOSPHORYN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37001:SF5">
        <property type="entry name" value="RIIA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="845"/>
            <end position="1468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1505"/>
            <end position="2163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="845"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="858"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="883"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="902"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="920"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="941"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1005"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1025"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1050"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1065"/>
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        </location>
    </feature>
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        <location>
            <begin position="1090"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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        <location>
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        </location>
    </feature>
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    </feature>
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        </location>
    </feature>
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        <location>
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            <end position="1660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1661"/>
            <end position="1674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1675"/>
            <end position="1774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1781"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1830"/>
            <end position="1846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1857"/>
            <end position="1869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1870"/>
            <end position="1921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1929"/>
            <end position="1962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1971"/>
            <end position="1995"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2002"/>
            <end position="2097"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2104"/>
            <end position="2121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2128"/>
            <end position="2145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2152"/>
            <end position="2163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2163" mass="219792" checksum="BF8640ABFEE5D638" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6V4</accession>
    <name>A0AAD8Y6V4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Enoyl-CoA hydratase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_008818</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6V4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051750">
        <property type="term" value="F:delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.12.10:FF:000004">
        <property type="entry name" value="Delta3,5-delta2,4-dienoyl-CoA isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045002">
        <property type="entry name" value="Ech1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43149:SF1">
        <property type="entry name" value="DELTA(3,5)-DELTA(2,4)-DIENOYL-COA ISOMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43149">
        <property type="entry name" value="ENOYL-COA HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1740723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="301" mass="32414" checksum="E9B50D46378494F5" modified="2024-05-29" version="1">MEASKKHPLDTFTHLSITYHESLPHVTHIKLNRPRKRNAINALMWREIGEAFRQIGTIGDGTRCVLLSGSGKGFCGGIDITDEKFFSGISPDNSSDDEESSIDMARKALAFKPQIIEMQAAFTALEECPVPVVAAIHGACVGAGIDMTCCADVRICSPNTVFSIREARLGLAADVGTLQRFPKLVGFGSRVRELCFTGEDFSPEDALNIGFVSRISKSESQLLGEANQIISKIIANSPVAVTVTKSSLNYSRDHTVREGLDHVALTNSAALMSEDLVKSFMMTSGGGGAAEFAPLQPHSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y836</accession>
    <name>A0AAD8Y836_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pre-mRNA-processing factor 40</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_008865</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.440">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036517">
        <property type="entry name" value="FF_domain_sf"/>
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    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
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    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039726">
        <property type="entry name" value="Prp40-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
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    <dbReference type="PANTHER" id="PTHR11864">
        <property type="entry name" value="PRE-MRNA-PROCESSING PROTEIN PRP40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11864:SF0">
        <property type="entry name" value="PRP40 PRE-MRNA PROCESSING FACTOR 40 HOMOLOG A (YEAST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01846">
        <property type="entry name" value="FF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00441">
        <property type="entry name" value="FF"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81698">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51676">
        <property type="entry name" value="FF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="310"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="4">
        <location>
            <begin position="788"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="domain" description="FF" evidence="5">
        <location>
            <begin position="987"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
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            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="485"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="819"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="868"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1282"/>
            <end position="1310"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1122"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="211"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="487"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="550"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="578"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="588"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="602"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="631"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="829"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="886"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1291"/>
            <end position="1310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1740770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1310" mass="145033" checksum="3826F4C7A933175B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y866</accession>
    <name>A0AAD8Y866_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y866"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="207" mass="22351" checksum="2D34A17D84CDD1CC" modified="2024-05-29" version="1">MGGMGGGCGFLQSQQPPIIIVNGKSGDGSGGGGDEETGNGDDGGKTDDENDDNSKGFSSILLVSIIFVFIGSLLAFICVGKVYDVFEHSMENDYVSDYFVVNRQVALGIGAFATLCYCIAFMLAFYAGMKYKMKCKTKEKKQCCRDGLLIAAWVIFCLTSINNLIILILAFDEEARIYPEVALCAVIGSIAAWLFVFGWAEMTRRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y959</accession>
    <name>A0AAD8Y959_9STRA</name>
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        <recommendedName>
            <fullName evidence="3">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_007991</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
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            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y959"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="3">
        <location>
            <begin position="537"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="451"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="317"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="451"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1741513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="811" mass="88463" checksum="C085515EF93E1334" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9E0</accession>
    <name>A0AAD8Y9E0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007932</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9E0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041972140" evidence="1">
        <location>
            <begin position="24"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="244" mass="26664" checksum="FC32F13D5E16C5FB" modified="2024-05-29" version="1">MVTMSVWSCIAVISLALTDTTSCAFQSTTTVRQSSRTPTATSLHGIMEAVESLAAEAADTWSIQATPFLEPVDASKIEEKFQDRGDVLCLRVFGGRRLSPEPDNNTVKPGEGRRSRFVIAHADLGMDAMTAEEEYCTVVRCENVNVASSNTFPNALASIGVHLDNVGDIVIEDSNTVCFVVTPEVTKQCLRLLSKELVGTGVSLSVVDSHEFMPHGEMQEMKLSRVLERQMERKKLDAGYVQFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YA70</accession>
    <name>A0AAD8YA70_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007462</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YA70"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="370"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="472"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="513"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="667"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="303"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="890" mass="96031" checksum="EA6DAEB36A80F208" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YB54</accession>
    <name>A0AAD8YB54_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="7">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_006895</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YB54"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000031">
        <property type="entry name" value="Peptidylprolyl isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050689">
        <property type="entry name" value="FKBP-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516:SF443">
        <property type="entry name" value="FK506-BINDING PROTEIN 59-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 7 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="8">
        <location>
            <begin position="19"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1742330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="112" mass="12168" checksum="C0A8EB737A7BB858" modified="2024-05-29" version="1">MGFTKTILRAGTGAMPRRGQEVIVHCTGYGKNNNLAEKFWSTKDPGQQPFTFAVGLGQVIKGWDEGVIGMQLGEIAKIHCSPDYAYGAGGFPAWGIMPNSELVFEIEVLSFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBQ1</accession>
    <name>A0AAD8YBQ1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBQ1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042125166" evidence="2">
        <location>
            <begin position="22"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="310" mass="34304" checksum="FD599DC67F143996" modified="2024-05-29" version="1">MKLLFISAAMAVFAAAPGAVASSSSRGVESYDSEPSAPSFDVYPQDSDSSKDGLMDSEPVDNNNMFIALENPNNPNCDGIGPNTCENRVACIWMCDTFRGSDRDLGCCEYKADQRRTPTRRPQRNPTRRPTRRPTGSSNRDPSFDSGLDAGRTEANRLWRNAGNRCSSAWGGFQNDVNRQIRTKGWNRNDGDWRSNAFNRGARAGMEEVVVEKEKECFRDSADECVDLGNAAAREIAYAFCPRGFGTTASGERPQWRRNCRDAAVDQCRGQVSGEVRDECGGGFSTNELRTLQNKCRNKVLTMIGDRSED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBU7</accession>
    <name>A0AAD8YBU7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Isovaleryl-CoA dehydrogenase</fullName>
            <ecNumber evidence="9">1.3.8.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_007006</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.8.4" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBU7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008470">
        <property type="term" value="F:3-methylbutanoyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006552">
        <property type="term" value="P:L-leucine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884:SF12">
        <property type="entry name" value="ISOVALERYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="8">
        <location>
            <begin position="13"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="7">
        <location>
            <begin position="125"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="6">
        <location>
            <begin position="236"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1742441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="381" mass="41565" checksum="5C1A3983DA5A4601" modified="2024-05-29" version="1">MNTNSLTKLFNPTDDHAALREMVRSFTEREVEPQALDTIEVKHSINDGLGILGLTAPDEFGGTGLPDATAVSIVHEELSYSDPALCLSYLAHSILLVNNLAVNANDEQLALFMPGICDGSKIGGMCMSEPNAGTDVLGMKSNAVYDSARDGFILNGTKMWITNGTLTGKETGDLFLVYARTGPRRGQILLSLWWRKAWRDKLGMRASPTAELVFENVFLPAKTHVVGDVNGATLCMMRNLEIERVALAAMAVGIARRSLDEMIAYASNRPALARIQKHISESYAEYMAGKCYLYAIANGLDLSTYGNGLDADGVKLYCATMAKNVADRAIQVMGGYGYCGEYTVERLWRDAKLLEIGGGTNESHHKNMARDLHKLDGNKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBU8</accession>
    <name>A0AAD8YBU8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peroxisome biogenesis factor 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007147</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBU8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045046">
        <property type="term" value="P:protein import into peroxisome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006966">
        <property type="entry name" value="Peroxin-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28080">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28080:SF1">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04882">
        <property type="entry name" value="Peroxin-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="67"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="289"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="206"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="84"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="531" mass="59768" checksum="AA4CD3982C558882" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCW2</accession>
    <name>A0AAD8YCW2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">2OG-Fe(II) oxygenase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_005875</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCW2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF236">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="6">
        <location>
            <begin position="163"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1743254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="357" mass="39224" checksum="90E7DB475F9A3968" modified="2024-05-29" version="1">MVAENNLGDDDSAGSVDTQDVFLEMFGLPTFSCVSSVVADDDENDIPSVKQLSVPQNCSRYIHKPCDVASFVIHNFLNADECQELIHLANTLSSTGFHYVTEAAHTDEEGTTHIVKLQEANKHKLSVFEHAPTTENLWKNLETIIMPHITTFMKHTLCGKPIGLNPRLRVLRYDAPDKDVFEPHFDATTRVNESTSLLTVLIYLNDGGGKDFDGGETCFLDSKSMKLNEATAIVTPSTGDVVVFEHDLFHSSAPLKFGTKHILRTDVLFQPDQEGGVELPRGESKGSSENLAATLFDVCQQLSVSEDVQNALGDIGLIDLSIEALFNPGEAVVKSILRDVLDDHNADMIFQAAMDCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YE73</accession>
    <name>A0AAD8YE73_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc finger CCCH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_003959</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YE73"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050974">
        <property type="entry name" value="Plant_ZF_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12506">
        <property type="entry name" value="PROTEIN PHOSPHATASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12506:SF50">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="8"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="52"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="133"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="8"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="52"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="133"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="331"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="386"/>
            <end position="405"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="424"/>
            <end position="447"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="463"/>
            <end position="482"/>
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    </feature>
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        <location>
            <begin position="163"/>
            <end position="173"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="332"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1744668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="518" mass="55311" checksum="06A5ACAA5A451AFC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YED7</accession>
    <name>A0AAD8YED7_9STRA</name>
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        <recommendedName>
            <fullName evidence="2">proton-translocating NAD(P)(+) transhydrogenase</fullName>
            <ecNumber evidence="2">7.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">QTG54_005631</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>NAD(+) + NADPH + H(+)(in) = NADH + NADP(+) + H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:47992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="7.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.1" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
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    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:proton-translocating NAD(P)+ transhydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05304">
        <property type="entry name" value="Rubrum_tdh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1220:FF:000002">
        <property type="entry name" value="NAD(P) transhydrogenase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026255">
        <property type="entry name" value="NADP_transhyd_a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024605">
        <property type="entry name" value="NADP_transhyd_a_C"/>
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    <dbReference type="InterPro" id="IPR034300">
        <property type="entry name" value="PNTB-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00561">
        <property type="entry name" value="pntA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006942">
        <property type="entry name" value="PRK09424.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10160">
        <property type="entry name" value="NAD(P) TRANSHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10160:SF19">
        <property type="entry name" value="PROTON-TRANSLOCATING NAD(P)(+) TRANSHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01262">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02233">
        <property type="entry name" value="PNTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12769">
        <property type="entry name" value="PNTB_4TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01002">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="84"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="181"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="254"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1017"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1051"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1102"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="domain" description="Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal" evidence="16">
        <location>
            <begin position="596"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="domain" description="Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding" evidence="15">
        <location>
            <begin position="749"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="977"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="977"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1744034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1136" mass="122320" checksum="6A14649DFAD6A6D9" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFB4</accession>
    <name>A0AAD8YFB4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HPt domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004699</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFB4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="entry name" value="HPT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="Histidine-containing phosphotransfer domain, HPT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HPt" evidence="2">
        <location>
            <begin position="32"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="1">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="143" mass="15736" checksum="FC9F56BBD8564F17" modified="2024-05-29" version="1">MNNKVASEKIAVKMSDGDVIDWQEAMDQCGDDEEFLRELLSDLRGEIDAQLVKIEDALKTVNDQSFLLIMRASHVIKGASSNLMCGQLRETSTNLEQGAAGANQIETANTSALEAETVKVKDIFEKLKTAVDNYHKFLDSVGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFT7</accession>
    <name>A0AAD8YFT7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Haloacid dehalogenase-like hydrolase domain-containing protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_004763</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HAD-like hydrolase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFT7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006355">
        <property type="entry name" value="LHPP/HDHD2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01458">
        <property type="entry name" value="HAD-SF-IIA-hyp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288">
        <property type="entry name" value="4-NITROPHENYLPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288:SF46">
        <property type="entry name" value="HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13242">
        <property type="entry name" value="Hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00039666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1744230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="346" mass="37230" checksum="60B7E21AAAB41B73" modified="2024-05-29" version="1">MASRVRATGNNFILASLLATLSYLPFQLVAQFTLIVCVLLFVVDPFPTSRLAPKLILANNKAIKAALIDISGTLHIGDEAIPGAVDACRKLFQYNHQLKVVFLTNTSKVSSETLLHQLRDMGFDESCIPDRDAILTSVNATRQYLVTNELRPYCLVEDDLVEKDFQGVEMNDPNCVLVGLAPSKFSYDKLNGAFRLLSKLKGELEHADCGDKPSLIAIHRAKHYRDSDHQLSLGPGGFITLLEQTAGVTAHVVGKPSHAFYHAAVSSLGVDPANVVMVGDDVVGDIKGSLEAGLGGAILVQTGKYTDGDELGNKTDGVLPTLTLRSIVEAVDCICFCVEKGTTSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YG72</accession>
    <name>A0AAD8YG72_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nuclear protein localization 4 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004629</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YG72"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08061">
        <property type="entry name" value="MPN_NPL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016563">
        <property type="entry name" value="Npl4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007717">
        <property type="entry name" value="NPL4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12710">
        <property type="entry name" value="NUCLEAR PROTEIN LOCALIZATION 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12710:SF0">
        <property type="entry name" value="NUCLEAR PROTEIN LOCALIZATION PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05021">
        <property type="entry name" value="NPL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nuclear pore localisation protein NPL4 C-terminal" evidence="1">
        <location>
            <begin position="91"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="343" mass="39027" checksum="1E3BAD832CFC3286" modified="2024-05-29" version="1">MSLRDIKKSWTLNEFNAMDDKYNFKIKRQESSFVGVEGLHLESGAVESFQNYLRRFQFRQQREEEDRSHLRQGWGARMPQKNESKVKKNKKVIVEAIYEPPQEADADAAEGFVMLDDDQEENVEQVASLLGLRKVGWIVGQPPRETGFQFSAAEVIMAAELQLECAQGVEETPFVTVRCTVGDEGNVIVEAFQVSLQCMEMVAEEALDIGPNPGFCYVNETFTAIQEGKPSPTVENNFFLTLVPIHGYQSDMFVTQFPFVNRPFDDRQQTHDEMKRQLTKSGQAGWTFIDLLSDFALLLYLCKFLDVSQDMPKICESVKDREVLLDDGYKIIISSMAGMDGSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGP7</accession>
    <name>A0AAD8YGP7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002803</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGP7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08267">
        <property type="entry name" value="MDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050700">
        <property type="entry name" value="YIM1/Zinc_Alcohol_DH_Fams"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695:SF294">
        <property type="entry name" value="RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="11"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="292" mass="31152" checksum="D440BC1B37E7BD27" modified="2024-05-29" version="1">MRAAIRTGLLGTTIAFTKDQPHPLPDTAELKPNEILIKVKSAAINPVDYKLPRFIGGKGVGFDVSGVVERVCATTDFSVGDNVFGRVGISSGSLADYAIVSTDRVAKKPEWLSFDEAAAIGVAYLTGVHAFKLGSVKEGSSVLVIGASGGCGLAGIQLAVAMKANVVGICSGKNFDFVRGESGIDQMENINLELVDYTDDKAMSEFKEKNVGKFDCIYDTATGSGHGENYVSSMAKLLKDVTGEYVQINGGIATLMRYFTGTMKPQQNFFFTSDEDNQTDLVEITRLLKSTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGZ3</accession>
    <name>A0AAD8YGZ3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003861</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGZ3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050817">
        <property type="entry name" value="DjlA_DnaK_co-chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24074">
        <property type="entry name" value="CO-CHAPERONE PROTEIN DJLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="85"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="224" mass="25375" checksum="E1679B36B40E81DF" modified="2024-05-29" version="1">MISSRTIDSGRELTGWDLGSHIILSPILAAMLHPRAPSTSIKALLVVGSVFFGGANAFSAGNTGSTGQPQSSFSNNPPPLPSTTTPYEILGFDRFPEDFSLIQRRYREMARTYHPDRLVGPDATAEEREIANTNFQRINEAYDTLKTRQDEEEIEVIMMGGNGKRERKVKYKTSTEIREKNPNRVNYDRIVENQNRQNVKAESWIDRGIEYGRHNGDFGPVRRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YH14</accession>
    <name>A0AAD8YH14_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Molybdate-anion transporter</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Major facilitator superfamily domain-containing protein 5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Molybdate transporter 2 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_003293</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YH14"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015098">
        <property type="term" value="F:molybdate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:monoatomic ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008509">
        <property type="entry name" value="MOT2/MFSD5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23516:SF1">
        <property type="entry name" value="MOLYBDATE-ANION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23516">
        <property type="entry name" value="SAM (S-ADENOSYL METHIONINE) TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05631">
        <property type="entry name" value="MFS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041899620" description="Molybdate-anion transporter" evidence="13">
        <location>
            <begin position="26"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="410"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="457"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="490"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="517"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="554"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="580"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1745369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="612" mass="63915" checksum="487D11A968650052" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHF4</accession>
    <name>A0AAD8YHF4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">L-galactono-1,4-lactone dehydrogenase</fullName>
            <ecNumber evidence="3">1.3.2.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004537</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.2.3" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHF4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016633">
        <property type="term" value="F:galactonolactone dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016899">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010031">
        <property type="entry name" value="FAD_lactone_oxidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762:SF1">
        <property type="entry name" value="D-ARABINONO-1,4-LACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762">
        <property type="entry name" value="L-GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="2">
        <location>
            <begin position="43"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="380"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="441" mass="47541" checksum="839B3DFC4A6EE0F8" modified="2024-05-29" version="1">MRQQPLPLLLGQPPHTNSSGSKEDIEEEEESTRILNWSGTHHVDLAPGTYHEPETQLELEALVADAYRKGQHIRPVGSALSPNGLAFDSRGMVCLSNLDKIVEINKDEMTVTVQAGARVSQVLDALRPHGLTLPNLASIAEQQIGGFVSVGAHGTGALIPPCDEFVTALTIVTPSENGVVKMTEATHGQLFRLARLGLGGLGILSVVVVTNDDENDLPLLGPGTEVSDGKGGKKKIVTAEDIKSKFSTDEQFKPLRDLLRKLLANKNDTSLDDDMINGMGFGDLRDVILASGNMLDPDHVKRCNKAEHAFWAKAGGIDLAPSDQKLQFDCGGQQWVYEVCFPSGTYGMPGTASIDFMEDLLKEIESSGLPAPAPIEQRWSSGSTSPLSPASVGPQVNDSYDSKNSLFSWVGVIMYLPSEDFDPTGYRRQFITESSKISIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHL1</accession>
    <name>A0AAD8YHL1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002770</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHL1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="315"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="459"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="537"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="644"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="703"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="148"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="537"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="554"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="593"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="704"/>
            <end position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="772" mass="83255" checksum="2BD126EC239CED29" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHX5</accession>
    <name>A0AAD8YHX5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">26S proteasome regulatory subunit RPN11</fullName>
            <ecNumber evidence="9">3.4.19.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_003425</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.-" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHX5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08069">
        <property type="entry name" value="MPN_RPN11_CSN5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000001">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056263">
        <property type="entry name" value="RPN11_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23594">
        <property type="entry name" value="RPN11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="5 9" id="KW-0647">Proteasome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="8">
        <location>
            <begin position="32"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1745501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="310" mass="34325" checksum="DA999DAE2EE9C196" modified="2024-05-29" version="1">MDRIQQLMRGMPGGGMGGPPSDSPTPDCSEKVHVSSLALLKMLKHGRAGVPMEVMGLMLGQFVDDYTINCVDVFAMPQSGTSVSVEAVDPVFQTKMLDMLQQTGRGEMVVGWYHSHPGFGCWLSSTDINTQSSFEALNARAVALVVDPIQSVKGKVVIDCFRLINPQLMMLGHEPRQSTSNIGHLNKPSIQALIHGLNRHYYSIVIDYRKNELEEQMLMNLHKRNWTTGLTVSPFEEQSKNNASVVDKMLKLSADYNERIVSEEGKSEKEILVENVGKVDPKKHLEGCVSDLMSSNIIQCLGTMLDTVIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YI38</accession>
    <name>A0AAD8YI38_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosome biogenesis protein BOP1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_003878</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat BOP1/ERB1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YI38"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070545">
        <property type="term" value="C:PeBoW complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000466">
        <property type="term" value="P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000576">
        <property type="entry name" value="Ribosome biogenesis protein ERB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BOP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028598">
        <property type="entry name" value="BOP1/Erb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012953">
        <property type="entry name" value="BOP1_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17605:SF0">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BOP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17605">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BOP1 BLOCK OF PROLIFERATION 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08145">
        <property type="entry name" value="BOP1NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01035">
        <property type="entry name" value="BOP1NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="BOP1 N-terminal" evidence="9">
        <location>
            <begin position="217"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="520"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="798"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="56"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="131"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="172"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1745954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="887" mass="99076" checksum="DCF8E4E1114E124E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJ32</accession>
    <name>A0AAD8YJ32_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">KH domain (Type 1)-containing RNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_003894</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJ32"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055256">
        <property type="entry name" value="KH_1_KHDC4/BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22675">
        <property type="entry name" value="KH-I_KHDC4-BBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="138"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="282"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="401"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="497"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="29"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="232"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="577"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="713"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="38"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="588"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="713"/>
            <end position="747"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1745970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="764" mass="77322" checksum="6F9B580F6D0A338E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJC4</accession>
    <name>A0AAD8YJC4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003206</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJC4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="14"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="105"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="477"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="172"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="207"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="247"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="260"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="296"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="345"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="628" mass="70233" checksum="A1B9A8FA3E82EEDF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKI7</accession>
    <name>A0AAD8YKI7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002558</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKI7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="257" mass="28127" checksum="515D992E0FD1C8A5" modified="2024-05-29" version="1">MSPRRSLLAGLWSLVGLLTTAGFVIAISFAIASQKYDPNYNNGNYYNNDDRDEDDRNRNNNGVITVTSRAMVFAAIWTAILSGILVIYGTVLLGVRMPFTGKYYSCCLGNVHRMTPLTLGSFAGSLLMFANLTLVCAILFGEFQIIPSFGERGDQNQNNEEYNNTSVVDDSSYAFSVLCIFFTGMYAAFAILIFYFSNSLLEESVADARGDTSVIGERSSSEMGQGVGYIGGNRFDVVGRKSYGGKAANNAHRHEVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKP2</accession>
    <name>A0AAD8YKP2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phosphatidate cytidylyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000102</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKP2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004143">
        <property type="term" value="F:ATP-dependent diacylglycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006654">
        <property type="term" value="P:phosphatidic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037997">
        <property type="entry name" value="Dgk1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31303">
        <property type="entry name" value="CTP-DEPENDENT DIACYLGLYCEROL KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31303:SF1">
        <property type="entry name" value="CTP-DEPENDENT DIACYLGLYCEROL KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="157"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="245"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="281"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="355" mass="38717" checksum="DE836C76D9424F3B" modified="2024-05-29" version="1">MKLSSSFSIGILISPWLVAATLAAVNFPFAPRVLPHHTSRVYSSSLDVNNHAAAKHALAYTLMQQRGGSTATSAPSNEDFTNELPSFSESDNEGHLEIAKKLKNRNATNLSRKITHAAFGIFFACLNQFIPHAKFMPLMYGITGSSLIIELLRYRKGFGWINTVLHFFLGGALRKHEMEGKFTGSFYYFAGVTVSAYLFPQTAATMGICQLALADPSASFFGRRTRHIYWSRIEGQLGGIGRNKGLLGFLGGALFCFPFNYRVFKIAKWGAGGIPGGNGSLIMVSLLLGMAGAFADLAVPTPALVMPKKILGVPVPPFHVDDNFVVPIFSGWACTKIFEYVGWDQGLKLAEHIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKQ4</accession>
    <name>A0AAD8YKQ4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_000310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKQ4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1748371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="487" mass="52224" checksum="8AE68FDD814E079B" modified="2024-05-29" version="1">MSVATGVGSVSNAALNRLSRQGLALAGGVVIAGTGSRSGRSGSHDYARKDAAQVVIRWIPRLHKMDSVSTLLAYSERSGEDAFSKHSKKRAQRMMHYNVSFQPFTATIHPKSPAKSNRMRHNVSFELSSFRSTDVSERDDDASLSEESLNSSGSIFMRTPTSFPPTPTSRLYYFERGSRFTENVIFLARDQLRVERGLDNQNEQTRAMSSALREGSRLAVFDAADAGGGGIALSCGQHIATKVGNALYCSTRSMIPVMRNSYVYFEISVSPPPSMDASGNNVNTQVAVATLSIGLSTLEMPLNTLVGAWKGSVGLCSTGQILQAGQWLSSNSQEHSTYGCNSTVGCLVYIDDTSAFDTWEGKNVVADITFNINGCLIPLAATANEDAESDAADHIGDSTLSLVAPKAQELFPTVTLHSPATCVMCRFSADDLLANSRKEIGAPHGVTVYSVDGSVLLDDNSNSVEDVDDFLDTSSALNAFPHEEVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YL09</accession>
    <name>A0AAD8YL09_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YL09"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="195" mass="21544" checksum="AD48DD03EF1C850E" modified="2024-05-29" version="1" fragment="single">FFYTSSSAQQASNNHSTPLPRSSVSYYYFLLCTMKMINHRIPFAAATLLLAFFASVGVVSSFTITTPRAASRAVVSNNQPWNFISTQQTFLSYPADGTTTSLQMSGGSNPDVDTDGIGAGKYLLFLVMLVNVWAFSIPVEFRRAQFCTEEQVRLNPDSHCITFENWKSGIIDHYANGGGVDFDFTVEEGNKWIGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMD5</accession>
    <name>A0AAD8YMD5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histidine phosphatase family protein</fullName>
            <ecNumber evidence="2">3.1.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000576</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMD5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07040">
        <property type="entry name" value="HP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF44">
        <property type="entry name" value="PHOSPHATASE C1620.13-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042195766" evidence="1">
        <location>
            <begin position="19"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="263" mass="28313" checksum="51B2415D65D9D5D1" modified="2024-05-29" version="1">MTALRLLALSIITGSCSAFTLGADGKNAAPAKMCDVENIPILDEIPEGHKRLFMVRHGEVINPGGDRPVYYGAMDVPLSPLGELEAIEAGNYLKRFDLQHVASSPLSRAMFGARQVCDNQNESNDVVVFEGFKELDRGAWCGKTKDEIGADNLARFDACDESVTPGDGGESYPTLKSRVIASRDDLLEMTNVGRASAIVSHLQVTRAMLSDALEMDIKEMAGLEIGTASITCVDYCSATGKQTVRFQSFKPESGLEQSKDGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMJ4</accession>
    <name>A0AAD8YMJ4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Calpain</fullName>
            <ecNumber evidence="7">3.4.22.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_001834</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.22.-" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMJ4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00044">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022683">
        <property type="entry name" value="Calpain_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036213">
        <property type="entry name" value="Calpain_III_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036181">
        <property type="entry name" value="MIT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051297">
        <property type="entry name" value="PalB/RIM13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46143">
        <property type="entry name" value="CALPAIN-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46143:SF1">
        <property type="entry name" value="CALPAIN-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00720">
        <property type="entry name" value="calpain_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00230">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49758">
        <property type="entry name" value="Calpain large subunit, middle domain (domain III)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116846">
        <property type="entry name" value="MIT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="6">
        <location>
            <begin position="286"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="212"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="341"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="522"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1747871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="891" mass="100151" checksum="ABD97CB158625F5E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMQ8</accession>
    <name>A0AAD8YMQ8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_000026</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMQ8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="4">
        <location>
            <begin position="25"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1748087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="230" mass="25903" checksum="D5237F142860453D" modified="2024-05-29" version="1">MRQRPRRPTTFIVLHATAEVDDIELKNCDDCDLVRYCSDKCQQDHRPNHEAKENRKNRKKRVAVKDPVALRELGGEHYDKGDYSGAFPYLTEAAAFGDMYAHYSLSVMYGEGKGVEKDDEMAWYHLEEAAIGGHHLARYNLAVRERENGRFDRAVKHFIIAANLGDDASIKQLRIGYIFSLGYTDGKVRKEDFASALRAHQAAVDGMKSPQREAAAKAEAAGLLIDDCRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YN26</accession>
    <name>A0AAD8YN26_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CRC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_000269</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the lin-54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YN26"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005172">
        <property type="entry name" value="CRC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005114">
        <property type="entry name" value="Helicase_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033467">
        <property type="entry name" value="Tesmin/TSO1-like_CXC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33418">
        <property type="entry name" value="HELICASE-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33418:SF1">
        <property type="entry name" value="HELICASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03457">
        <property type="entry name" value="HA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03638">
        <property type="entry name" value="TCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01114">
        <property type="entry name" value="CXC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51634">
        <property type="entry name" value="CRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRC" evidence="6">
        <location>
            <begin position="122"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="633"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="686"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="155"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="54"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="633"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="697"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1748330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="737" mass="83730" checksum="D7B35AF2455B16D6" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPG7</accession>
    <name>A0AAD8YPG7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPG7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050626">
        <property type="entry name" value="Peptidase_M16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43690:SF18">
        <property type="entry name" value="INSULIN-DEGRADING ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43690">
        <property type="entry name" value="NARDILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1749002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="209" mass="23520" checksum="6B7025C88E68DBD8" modified="2024-05-29" version="1">MSLAVVAPQSLPQLRKYVSDAFGDIPNRQIKPPEDKAEVGKCTRCSDNADLSDFGTFEVTVELTPKGLNAIDDVCEAIFSYIQMMKTNPIPNYVFDENLQLDELEWRFTTKGQPTNYVQSLVTAMDKFPPSLYIAGPRRVALLETPTTLISSDQPRTSFKSNEQREILKSASTDLVNRLTVDNSFLTVFSKSFEGRQLKMRNGTVQHIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPU6</accession>
    <name>A0AAD8YPU6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_001029</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPU6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="36"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="210"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="265"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="231"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="295"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1749090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="373" mass="40166" checksum="E7A138897B6253A2" modified="2024-05-29" version="1">MSYQPPRVGTGMSVRSTGMPPGSSSGRPPAASNLSCNKCSKPLATTCFLCSCDCIFCEECTYSHFERSSQCPTCGRRLAENDFTELVVADANTGTDVVKSNMQSLLTKKHSGGMLQYSEICQSLIRQVDSTKQATKFLLKQLLLESHKSGRNNLMASRTHEALQAENTQLKQLNSSQRLQYEQTITTLQNKLNAREATIAEQNKMIDQFRKYHGGGGGGGRGGHAHMVPNSSSASFSSSSSLGGGAPPLRGLMAQREANKIVQQNTLNGRSQPFMNAMQNSSRSKSPGANFRPFSGGSTEGGSVSSNTPRIRDLSAGSGYHFTGMSNHNQPLNKRRRGGTPGSMGNGTPHTAMSPTTAFTLNQGPHSHRPHRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3D6</accession>
    <name>A0AAD9D3D6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DnaJ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_016897</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000067">
        <property type="protein sequence ID" value="KAK1732416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3D6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45188:SF2">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45188">
        <property type="entry name" value="DNAJ PROTEIN P58IPK HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13174">
        <property type="entry name" value="TPR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="74"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="240"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="6">
        <location>
            <begin position="421"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="144"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="393"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1732416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="530" mass="59885" checksum="93E671063FF905BA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3L4</accession>
    <name>A0AAD9D3L4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016648</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000061">
        <property type="protein sequence ID" value="KAK1732671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3L4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="137" mass="14772" checksum="13563578CD77544E" modified="2024-05-29" version="1">MTVEGRPRSTSFSSTPTFSSDLAKLKSSLPQSPSPSSSSSCTVSSYKEAIAIASTFDVLGNNSTLTPKLKLTSEDDWIDFFQKSGAVDTTSSGVNVNMEKFLRYCFDMAYKMPPSPSNRVLREHVRGASGTVPSLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3S8</accession>
    <name>A0AAD9D3S8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Tubulin-tyrosine ligase family protein</fullName>
            <ecNumber evidence="7">6.3.2.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_016404</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.-" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3S8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070740">
        <property type="term" value="F:tubulin-glutamic acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004344">
        <property type="entry name" value="TTL/TTLL_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241">
        <property type="entry name" value="TUBULIN POLYGLUTAMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241:SF147">
        <property type="entry name" value="TUBULIN POLYGLUTAMYLASE TTLL7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03133">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51221">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042280327" evidence="5">
        <location>
            <begin position="23"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="6">
        <location>
            <begin position="24"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="567"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="662"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="750"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="96"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="568"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="671"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="759"/>
            <end position="780"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1732866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="998" mass="115287" checksum="B5857F043D23EB96" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3Z7</accession>
    <name>A0AAD9D3Z7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Proteasome subunit alpha type-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3Z7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005839">
        <property type="term" value="C:proteasome core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="335" mass="36486" checksum="BF776FE8667E0AF7" modified="2024-05-29" version="1">MIRSMISPCFSGSRIQRNMTSMYYCFVSFIIVVSLFHHRIAFADGSSIGSRHSYSLTTFDPSGNLDQVGRAVRASMLGAPVVALSIPSSSETMVTTADSESSATPPEEGIYICIPLRFLGTTSPLIIDDGTPRIVPISSYICICHTGVGADGRALCDIAVRLALDYRYVYGEEISLEELLEALAEKVQEMTMKAGARPYGCALLVACLGSGNVDGGDKGREATMYRIDPSGSVELLNANGDFNSENERRASLAFLGKWNSQKEKDLRSQLDSQQYTTEQQVQDALISAVDVNDDSSPTQSTPNEGKVAKHFYMLRLLAKVGCKYLGLIEKHVEMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4C5</accession>
    <name>A0AAD9D4C5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">WRKY19-like zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015799</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000048">
        <property type="protein sequence ID" value="KAK1733511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4C5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056866">
        <property type="entry name" value="Znf_WRKY19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24906">
        <property type="entry name" value="Zf_WRKY19"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="1">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="1">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="1">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="186" mass="19633" checksum="F83AFE1C87B0681B" modified="2024-05-29" version="1">MNQAKNRGVCRRHGAPIKQKQCSSEVCTNQVRQGGVCIRHGATIKRCSSEGCTKFAVKGGVCNKHGAKRKLCSSEVCTNHVVNGGVCKKHGAKIKRCSSEGCMNQAKQGGVCIRHGATIKRCSSEGCTKFAVKGGVCNKHGAKRKLCSSEVCTNHVVNGGVCKKHGAKIKRCSSEGCMNQAKEGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4V5</accession>
    <name>A0AAD9D4V5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000055">
        <property type="protein sequence ID" value="KAK1732990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4V5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="257" mass="29986" checksum="ADBC0F5005C95396" modified="2024-05-29" version="1">MESETNHDDNDRPTKTLRSSRPDLKVILGSSSSNEKNECIQWYHSQTLASKSKYIDAMLSTPMKEKDDLTISFPDITIGVWERMMLFLDSPIVARQMKARDASELAIYYDKYEFDEGRKLCEVVIIEYMKLTNRMEKKNTLDLDFIIELVDVTHRANMEEAFKVSMEYIWEKLRSADIRYGRLMFTEENLKKLSPLLKYSVNNRGRIWGPYGIQFTESNLITGSSGWDGKDDLVHFDDEQFAKVHIARSQKQAETYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D573</accession>
    <name>A0AAD9D573_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014764</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000038">
        <property type="protein sequence ID" value="KAK1734516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D573"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="242" mass="27432" checksum="764CCA39B25BE002" modified="2024-05-29" version="1">MNQPHQPSSMQQQTAQLQQCCWSWSNQLAPLHQPARTVSNNSFSSSSSTTTTSLSTADSDCCQHSSNAKKRRRTHNVHFASTSDLFMIPSKSSQDNESLWYTKQDFTNFKCDLRSSSKAMEESACVDILESIAYSLVTKTAMKHHIHLHPHEKILTRGIEHAVSPTVLKLMAHRRKVVTRKVLCEQARLRKQPGMNTKESERRMAAELAQCSMAASMFAKDWAVLKLLHDKRVIPLLNMYST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D745</accession>
    <name>A0AAD9D745_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013974</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D745"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="382" mass="42505" checksum="90236FCB474D288E" modified="2024-05-29" version="1">MVKFGRHVDFFVANELDAARQLYVIPYKDIQRKTCLDPPKPAAQPEDEEAPPEESPPSPFISPSSSPKPKPGQNFASGLSALFNPPSNNNNIDEIFLPEIDAVNSKETGSKGVRPAQTAVTLNNATGAELAKAIRSLRVGRRQQPDPIPVIPDDYGYDDPCNSEDEVDEQANAHFFANRFETEWRIALKRASADFERAMGLFWNEVFQGIIQHMEEDGEDDAIRGALPDAALQLYVSVAPADEAQNLFNFLKDIHATALINAEALRKLTKKFDKHHIDKIRTIDNNVYSLSAKLLPEVYASNFTVGLASVDAGLTLLRAFLNIDEEESLGDGEELRANKHLKKLTTMDIDSRELAVLSGGYLETRKILMLNWSRRGRKSWSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D772</accession>
    <name>A0AAD9D772_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cycloeucalenol cycloisomerase</fullName>
            <ecNumber evidence="2">5.5.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.5.1.9" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D772"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047793">
        <property type="term" value="F:cycloeucalenol cycloisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020532">
        <property type="entry name" value="Cycloeucalenol_cycloisomerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35136">
        <property type="entry name" value="CYCLOEUCALENOL CYCLOISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35136:SF1">
        <property type="entry name" value="CYCLOEUCALENOL CYCLOISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="250"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="309"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="329" mass="37772" checksum="45DA1A3D344F8BEC" modified="2024-05-29" version="1">MNDISALPIEAKMTAILFTMFAILVGMHSLQTPYDYDQNNTSKLPLLLPDPKNEPSKYCYEIFAWYYTAVWIGIFGFIVVSQSYELLTAWGYLGVCGGLALPLMLQPLLYPLASAPVVKNKIIINPDIQRPFYKRYSTKATIYLMTYAFIGNYWYTHYFYSVLKAEYTMPSHRLNDVPIAMFLATHFYFCTYHVCVGNGILRYVDKSYQKGWMKTILFWFTILSLSYFTAFMETLTISSFPYYSFEEREMAYTVGSAFYGIYFVVSFPGFYFFDAHIDDGKQKDRPVTLVDTFTTACGHGMMILLLLDFVRLYLGIPLVIGGVAFATTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7R6</accession>
    <name>A0AAD9D7R6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">rRNA methyltransferase 2, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_011994</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7R6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008650">
        <property type="term" value="F:rRNA (uridine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01547">
        <property type="entry name" value="RNA_methyltr_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050082">
        <property type="entry name" value="RNA_methyltr_RlmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015507">
        <property type="entry name" value="rRNA-MeTfrase_E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10920">
        <property type="entry name" value="RIBOSOMAL RNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10920:SF18">
        <property type="entry name" value="RRNA METHYLTRANSFERASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005461">
        <property type="entry name" value="23S_rRNA_mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribosomal RNA methyltransferase FtsJ" evidence="8">
        <location>
            <begin position="64"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00041184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR005461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1737127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="279" mass="30975" checksum="73BF67F28CD0FCB0" modified="2024-05-29" version="1">MFAAAHQSRVIRATSHISALHQLRSVGATSIRLKHKQSKSSQNWIQRQKKDPYVQKAQAQGLPSRASFKLQEINETHYPALIKKKGIPVNGKNKRLLQPRMNVVDLGASPGGWSLYASTQVKEGTIVAIDLLPLDDTKISLNLPNFNFIQGDFTESETKQLIVDALVQERANLVMSDMAQNFLGDSQTDALRTLNLCEQALVFSAGGSCFDSSYSPKSDEGMLAPGGSFLCKFFSCGKENEEDLMQAAKRAFRNVHVIKPKSSRKESSEMYLLAIDRRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8D4</accession>
    <name>A0AAD9D8D4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011589</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8D4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052394">
        <property type="entry name" value="LRR-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114">
        <property type="entry name" value="LEUCINE RICH REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="274" mass="29924" checksum="CC79A4052C8868B5" modified="2024-05-29" version="1">MKILATALTDKSCIVERLQLHYFSLQVTEFLEALKSEKCTLKTLHLYENKLTEEHARELAGVLRENTSIETVILNECEIDCAAAKALAVGLEGNETLRTMNLWDNHIQDEGGRALAEALKKNNALQTLNLWGNQIGDQGAKEFADLLRVNHSLRDLIFVYNKIGDDGGDELVDALELNEGIRNLDLFGNPLDQAIITDVYCMINDPSRSYYEGGLNKGEEGGFSENTTLGAPPTIDKSCFPILGGMHAADTESTASPTGVGELSACCWTEAVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8L9</accession>
    <name>A0AAD9D8L9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Trypsin-like serine protease</fullName>
            <ecNumber evidence="8">3.4.21.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_010935</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8L9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000002">
        <property type="entry name" value="Transmembrane protease serine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF91">
        <property type="entry name" value="AT26814P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042292717" evidence="6">
        <location>
            <begin position="25"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="7">
        <location>
            <begin position="39"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="292"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="295"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1738266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="455" mass="49616" checksum="CCA9ACAC405A2DE1" modified="2024-05-29" version="1">MKVQQTQSLSVLLGLVSYFASAEASSSTSMRNPHKHTRIINGTKAVDGRYNYFVALQHELIGHVCGGSLIAPDVVLTAAHCEHPDMLAVITRHDLDNRSDGTAIPIKGSLPHPNYDDFSFDNDFMLLFLRDPAPQDATFVKLNSNPNFPAAGGPVTVMGHGLTDPLGFGANEELLEVEVNVVSNEACEQSEGYLEIESAYLSYESLITDNMLCAADVGEDSCQGDSGGPLIVQGNDENGSTDILSGVVSWGFGCGDSDFPGVYARVSSAWTWIQNEVCNRSMYPPAEFDCDSLISSPTPTPQQTSSPTTSSQQTMTMTPTHTTLKSTSSPTTSSQPTLSPTVSCPPPYNSSFNYSVGDQVNFGEEIFICQPRDGSTQCTDDSSVWSHIKACCPTVFDNTRTDYQAYDKVSYESSMIFMCQPGPYEEYCNIHAYDLEWNDIQVDLYENAWTYVGEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8Y0</accession>
    <name>A0AAD9D8Y0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012483</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1737038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8Y0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="125" mass="13702" checksum="DCFD08E5C4090BCB" modified="2024-05-29" version="1">MTAASTPPIHVLRGILRHIKKTAPSSSTTAAATSSQSNSGNELSLHQHVISQYRQSISATPQQAQHLRKVAYDYLNLKKDLVERGRLHELDSGADMKLSPRELSRRAAARAGLQLPVMDEGHVDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9G6</accession>
    <name>A0AAD9D9G6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">IQCH-like ATP-grasp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9G6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056855">
        <property type="entry name" value="ATP-grasp_IQCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038752">
        <property type="entry name" value="IQCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14465">
        <property type="entry name" value="IQ DOMAIN-CONTAINING PROTEIN H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14465:SF0">
        <property type="entry name" value="IQ DOMAIN-CONTAINING PROTEIN H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24923">
        <property type="entry name" value="ATP-grasp_IQCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IQCH-like ATP-grasp" evidence="1">
        <location>
            <begin position="362"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="690" mass="76801" checksum="32AE4200CA91CAA2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9M7</accession>
    <name>A0AAD9D9M7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011218</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9M7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="171" mass="18917" checksum="811935E6122B1E4C" modified="2024-05-29" version="1">MADAFLGCKALTRIKFGDKLESFRERAFLACRSLERITIPLKDGMISDNAFQGCGNLKHVDLVEGAILHETIAALLLEEWKNDMKEEMASIKQILSTTPAGNVFGDVGGKVEAIRVWIGSVLHKTIHYKAQHQSYLNEAATTLQLALPNDIVIKNVLPFLELPSYTFGGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAY3</accession>
    <name>A0AAD9DAY3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAY3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="153" mass="17088" checksum="21DE1F5D18FFD4B9" modified="2024-05-29" version="1">MGGGESDDDDNGKMQSTHWCVLTPNMITRNSQINFQGNNMGHMGESLLPCWSLLFELGAMQQQQHGVRGKAAHTNNDSSFGCGIDTSALGPLRGWSKALVVEAMKCKIYDGRTANETKPNDQLHHPNLYLMSPYYRHMQYISHPSTRTSFVKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DB01</accession>
    <name>A0AAD9DB01_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009773</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DB01"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042247277" evidence="2">
        <location>
            <begin position="30"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="230" mass="24503" checksum="DC58B187693FB10E" modified="2024-05-29" version="1">MKNYIGNKRTHLVLAFLVSIIALEKQCQAAAAAASNRRNNNAAAFIIPSSPLSASINRRTNNFDLQRVSMLHTTTSLSMTFMDSSTSSLIAATQVLDSTTTTIIPQPQLLEEAPIVIEQLSPTTTIIVFIIGIIPFIWATIEFWRRIAVGASFGTGSDSVVIPSPFDGDDDSGLITIGEDGNPTSSRGRQTLDRGALGVAYVLFAVAAFSVGIAVASVVMGPKPEMMMPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DD60</accession>
    <name>A0AAD9DD60_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycosyl hydrolase 5 (Cellulase A) family protein</fullName>
            <ecNumber evidence="6">3.2.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_007217</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DD60"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901136">
        <property type="term" value="P:carbohydrate derivative catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041036">
        <property type="entry name" value="GH5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018087">
        <property type="entry name" value="Glyco_hydro_5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052066">
        <property type="entry name" value="Glycosphingolipid_Hydrolases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31308">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31308:SF5">
        <property type="entry name" value="ERGOSTERYL-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18564">
        <property type="entry name" value="Glyco_hydro_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00659">
        <property type="entry name" value="GLYCOSYL_HYDROL_F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="4">
        <location>
            <begin position="58"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5 C-terminal" evidence="5">
        <location>
            <begin position="586"/>
            <end position="673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF18564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1741644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="676" mass="76514" checksum="0BB8DA1EE5E5EE3D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DD75</accession>
    <name>A0AAD9DD75_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Serine/threonine dehydratase</fullName>
            <ecNumber evidence="6">4.3.1.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_007262</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.19" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DD75"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030378">
        <property type="term" value="F:serine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004794">
        <property type="term" value="F:threonine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018114">
        <property type="term" value="F:threonine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070179">
        <property type="term" value="P:D-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01562">
        <property type="entry name" value="Thr-dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000007">
        <property type="entry name" value="L-threonine dehydratase catabolic TdcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000005">
        <property type="entry name" value="Threonine dehydratase catabolic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005454">
        <property type="entry name" value="PRK07048.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43050">
        <property type="entry name" value="SERINE / THREONINE RACEMASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43050:SF1">
        <property type="entry name" value="SERINE RACEMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="5">
        <location>
            <begin position="26"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1741689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="338" mass="36290" checksum="D6E015DA19A83D0E" modified="2024-05-29" version="1">MAAADDLPTYKDVADAAAVLAGVAHHTPTETSRTLDDQLGVSCFVKCENMQRMGAFKFRGAYTAVNHYLNDADGKELKGVLTYSSGNHAQAIALASTKTLGIPSTIIMPTDAPTLKLKATQEYGGNVVFYDRYTEKRDEVAQKVKATLPEGTVFIPPYNHKYVIAGQGTVGKELIEDLQSKSIALDYLFVCVGGGGLISGISLAVKELSPKTQIIGVEPEAGNDAQQSLEQGQIVHIETPKTIADGAQTQHLGDLTFDIMQRNVSKIITVTDEQLVDEMKFFGERMKMIVEPTGCLGLAGLRKLVSSGEIEKGAKCGVIISGGNVDLERYCKLISSTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDK8</accession>
    <name>A0AAD9DDK8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">WD40 repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_007336</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the WD repeat WDR6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051973">
        <property type="entry name" value="tRNA_Anticodon_Mtase-Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14344">
        <property type="entry name" value="WD REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14344:SF3">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3 9" id="KW-0853">WD repeat</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="414"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="533"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="12">
        <location>
            <begin position="1301"/>
            <end position="1627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="562"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="7"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="1435"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="1443"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="1445"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="1566"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="1577"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1741763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1627" mass="178825" checksum="4BC9360F77FE33D9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEF7</accession>
    <name>A0AAD9DEF7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SH3 domain-containing Ysc84-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004710</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEF7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11524">
        <property type="entry name" value="SYLF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051702">
        <property type="entry name" value="SH3_domain_YSC84-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007461">
        <property type="entry name" value="Ysc84_actin-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629:SF2">
        <property type="entry name" value="SH3 DOMAIN-CONTAINING YSC84-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629">
        <property type="entry name" value="SH3YL1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04366">
        <property type="entry name" value="Ysc84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="Ysc84 actin-binding" evidence="2">
        <location>
            <begin position="84"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="260" mass="27799" checksum="2163DB0922593485" modified="2024-05-29" version="1">MSNKRPDRTTMEGMIWNANHVLDKALDPKTPGIPRGMIKNCKGVILLSMAEAGFIFSGTVGSGVIIAHNEDNSWSPPSALSVGGIGWGLVAGKEVKDVIICVMERGNVDTLSAETQVKIGGQLSATLGPVGREAETSLNFNGTSEIRGTYAYTWSKGVFGGISMETAVLKVRPKENARFYGKESVSSKEILENTLAAPKDMGVEDLHYKLDLLSKGKALVLTPAQVERKSSMRNLADEAGVLAKSVQTDVMEVDADEEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DF54</accession>
    <name>A0AAD9DF54_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006019</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DF54"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052920">
        <property type="entry name" value="DNA-binding_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43358">
        <property type="entry name" value="ALPHA/BETA-HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43358:SF4">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="2">
        <location>
            <begin position="340"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="602"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="103"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="294"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="323"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="608"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="625"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="650"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="702" mass="76950" checksum="F01C5E6DA1B10774" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFR2</accession>
    <name>A0AAD9DFR2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002673</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFR2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="196" mass="22239" checksum="A240B6D04D867843" modified="2024-05-29" version="1">MDPSDVERMRLKKQQQNAQRNEKDTAKESTLEDDVNVSEELRRVRMLWPELTKRTLTTFRARGLFRSTDLSNEEWEQLGRDLANCNQLESLNLEDAVGGADVGDCKTSFLFRGWTKSSSIKDMDLGCNGFGLEGVQSIVPFLQNASNLKYLDVKGNNIQSEGFNAIFRALRDSQIEELYCAKLYLQPIGNIRFGGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFY2</accession>
    <name>A0AAD9DFY2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_004938</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFY2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010699">
        <property type="entry name" value="DUF1275"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06912">
        <property type="entry name" value="DUF1275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="140"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="176"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="239"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1744405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="439" mass="48108" checksum="96B9615AB131E005" modified="2024-05-29" version="1">MIASAIFGVTLPNGRALYYFAAMANGLQNGMTSTYSANLIRTSHLTGTSTDIGLIAGQMLRGNMKNYWKFKVLVGLAASFWFGGLISFYSAQRFLSQSLWFSAALYLLVGMTHCVYVWEKVLETMASSLNPAGGGLEAGMTDEQIDRIFKTIDTDDSGTIDADELKVALDDMGMKLSEQCVASMLKVVDENGDGVVDILEFRTLVNIATERAKFRKEKKMARKKSSMFGLKSSFTDEASATGRQSVNLSERNGDEESSLKKFSILPPSIAEEEGNVLKGSGTLPRTFDEALPTRSKAGNGDTGNRAIVVTEARYPYAVVGCNKPWEDLCGFNESEAVGQNMSAMIQGPKTNREGIKKSMEELIGGADYVECETINYRKDGSTFKNFLQMGPLYDDNDEGDEEKGEREVAYFVGILKNIGEFAQSLTDGDWEENKNVVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG18</accession>
    <name>A0AAD9DG18_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004786</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DG18"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="156" mass="17601" checksum="CDA26BCFA0CA00A9" modified="2024-05-29" version="1">MDLTARQQPRTFWELLRCCKKDAADGDGDDFHNTTSSQVCRSTLDKDLSVSTTLDSPQTQSTLEADEDGQIFNDDINEVAREEADIIKQSSSSIEKEWHQQSIKAAIDNNEKPTDEFKDESFDDASVIFDNLTDFAEQLHQEVDTAVSNMVDALYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2024-10-02" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGK0</accession>
    <name>A0AAD9DGK0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="9" mass="1175" checksum="F68D140B1DD339C1" modified="2024-05-29" version="1">MHFKAERRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGX3</accession>
    <name>A0AAD9DGX3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003573</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGX3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051279">
        <property type="entry name" value="PP1-Reg/Actin-Interact_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24112">
        <property type="entry name" value="LEUCINE-RICH REPEAT, ISOFORM F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24112:SF9">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="394" mass="43504" checksum="0E76203BB117E5E9" modified="2024-05-29" version="1">MNNEAAINDLYIDWMENGVDDYLAWGFAVFEYTIRYETSALNHANAGETTEVVIMGFEQVAEGLLLHQDWMLPLWREFSEALARASARGVAIACLSMGHVELPINVLSLLAPALKVAQIKLLHLKNNGLRRDGIILLSKSIQMNQSLERLALKETHLLDVGCVVSLVEPSRHDNRLRSLSLDKCNIGLKGSLMSTLLHTLSLSNNIRNLSLAHNHIGANESEMIASYLATNPPITSLDLVGNLLSDADVVLITGALKANTTLRGLRLSGNPLGEASKVAISEAIYNISSLNAIHSSNHTCLVTSDFDIPDCNRYVSQNANRISKLLGVLFTEFAFTYLDDVPLVVVPYVLDFVQAPSFKLPLTRIFHLVRDWDTPMTNLRHVCEEMEAGSDMVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGY5</accession>
    <name>A0AAD9DGY5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003349</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGY5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="129"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="180"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="297"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="717"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="461"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="566"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="71"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="93"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="155"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="183"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="307"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="331"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="373"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="739"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="762"/>
            <end position="774"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="774" mass="86365" checksum="EAF9D28A859D16BD" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DI81</accession>
    <name>A0AAD9DI81_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_002403</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DI81"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042088231" evidence="3">
        <location>
            <begin position="23"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="49"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="570"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="192"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="298"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="391"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="49"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="98"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="141"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1747059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="682" mass="68894" checksum="8E7F66E9B0FA296C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIT2</accession>
    <name>A0AAD9DIT2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_000736</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIT2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1748797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="176" mass="19649" checksum="B18BCF46AA35A207" modified="2024-05-29" version="1">MTFIAKEATRRIRLTQSSDGLSNEREILPRDCVQIAWALGMMESDNVSVGDAFVYLVDAINEYWITRSGRPSQPLKGWKCADLVQMATALAHGRLDNQSVLSAVYEEALRRLRSRNGLSISEISILLWSQARMHLTKNFGAEFAEFPSAASQALLQRMGRSSMKMPPQEGANVAWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIW7</accession>
    <name>A0AAD9DIW7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MAP3K-like serine/threonine kinase</fullName>
            <ecNumber evidence="7">2.7.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_001293</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIW7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF288">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="69"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="421"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1747330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="441" mass="49189" checksum="C28BB6F923846D55" modified="2024-05-29" version="1">MVSKAAQEAYERKKAALAAAAASNTASSGITLAQLLPHAERKVAAMKSDSQYFDEEDLAVMPKFELNELTLGRVLGKGGFGTVSEISLIQCAGTQGDVQQEGEDEQAQQDKKFIADHCIREGGDARYAIKALSPEITSDPNKFFQGVLDMSVETMFLSVVDHPHIIKMRGVGACGMTHPEYFLVLDRLYDTLEARILTWKIQTKKANSVMNKLKKKSGEKNAEIMEIKLSYAYDLMGAIEFLHKKGLIYRDLKPENVGFNVRDDIVLFDFGLAREMHDKDKLSEHTWQLTGETGSLRYMAPEVAASKPYGYTADIYSIGIMLWEMLSMEKPFAGFNRMRHNDFVVLKGGRPKLDESWGKSLSSFIGACWNQDLTKRPSASRASNILKREVAKVSDGGASDLNNFRRKSTFVNRDSLRERRSIAKEGNGSSELDAYIPHADQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJL3</accession>
    <name>A0AAD9DJL3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">60S ribosomal protein L4-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_000483</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJL3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1370.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025755">
        <property type="entry name" value="Ribos_uL4_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_uL4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_uL4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013000">
        <property type="entry name" value="Ribosomal_uL4_euk/arc_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045240">
        <property type="entry name" value="Ribosomal_uL4_euk/arch"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19431">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14374">
        <property type="entry name" value="Ribos_L4_asso_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="Ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00939">
        <property type="entry name" value="RIBOSOMAL_L1E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL4 C-terminal" evidence="5">
        <location>
            <begin position="266"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="330"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="330"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="343"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1748544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="379" mass="41125" checksum="0A8885F760D5E8E5" modified="2024-05-29" version="1">MAARPLVSVFSLTGEKAGETTLPEVMTAPMRPDIVQFVHTNMAKNNRQAYAVSPWAGKNVSAHSWGTGRAVARIPRVGGGGTSRSGQGAFGNMCRGGRMFAPTKTWRKWHRKINGTQRRYAVASALAASAVPALVMARGHKVDDVPEIPLVMDSSIESAKKTSAAKDILAAVGALADVEKAADSKKIRAGKGKARGRKYTLRRGPLVIYKNNDGVEQAFRNLPGVELCCVDRLNLLQLAPGGHMGRFCVWSQAALDALNEIYGSEGKKIPEDIMANADLARIINSDEIQSVLNPAKRANKKYLRKKNPLKNIKALAKLDPYAAAARESEQRAEAARKDQKAALLKKKRDVSKSKKQYKAQGKAFYEQVSQQGDVCADGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJW8</accession>
    <name>A0AAD9DJW8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">KNTC1 third ARM-repeats domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000843</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005828">
        <property type="term" value="C:kinetochore microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990423">
        <property type="term" value="C:RZZ complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000070">
        <property type="term" value="P:mitotic sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903394">
        <property type="term" value="P:protein localization to kinetochore involved in kinetochore assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055405">
        <property type="entry name" value="ARM_KNTC1_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052802">
        <property type="entry name" value="KNTC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15688">
        <property type="entry name" value="KINETOCHORE-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15688:SF1">
        <property type="entry name" value="KINETOCHORE-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24515">
        <property type="entry name" value="ARM_KNTC1_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KNTC1 third ARM-repeats" evidence="2">
        <location>
            <begin position="1490"/>
            <end position="1653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1685" mass="183927" checksum="7AA79E96D6A14BF3" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DK63</accession>
    <name>A0AAD9DK63_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ER membrane protein complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001143</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the ER membrane protein complex (EMC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EMC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DK63"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039856">
        <property type="entry name" value="EMC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12760">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU367091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1749204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="287" mass="31327" checksum="820E4C5B5C4C8305" modified="2024-05-29" version="1">MGPEEDLPTLISQKDHLNVLRYVRAHQLREPNLVVNHGKILLQSKSLGDAERLASLEQICIAACDIGDLDLAESCLDSIVNPTSNNKSLIVTKQSSRYRKLLALCLEAAGNYESAGAVYDILLQDNPSNAYAAKRKYCILAAQPDLAAWNQMAEMCLSVSDFKGAAYCYEELVLGCPLDSNIHTKLGEVYCTAGGVENAKLARKHLAQAVQLDPNNLRAWYGLVAAAEGYLEEVEKISKNKREAEDEGVEVAKELIKFGGEKLVGIYKGTKLAKVVNAVLKESSESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1GZN9</accession>
    <name>A0A8K1GZN9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Large ribosomal subunit protein bL33c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rpl33</name>
        <name evidence="6" type="ORF">QTG54_017218</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="7"/>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2021" name="Front. Plant Sci." volume="0" first="0" last="0">
            <title>Chloroplast Genomes for Five Skeletonema Species: Comparative and Phylogenetic Analysis.</title>
            <authorList>
                <person name="Liu S."/>
                <person name="Xu Q."/>
                <person name="Liu K."/>
                <person name="Zhao Y."/>
                <person name="Chen N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CNS00100</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Plastid</location>
            <location evidence="5">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL33 family.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MW679506">
        <property type="protein sequence ID" value="UAM91418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_010200931.1">
        <property type="nucleotide sequence ID" value="NC_058701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1GZN9"/>
    <dbReference type="GeneID" id="68638068"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.120">
        <property type="entry name" value="Ribosomal protein L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00294">
        <property type="entry name" value="Ribosomal_bL33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001705">
        <property type="entry name" value="Ribosomal_bL33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018264">
        <property type="entry name" value="Ribosomal_bL33_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038584">
        <property type="entry name" value="Ribosomal_bL33_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001764">
        <property type="entry name" value="PRK00504.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001860">
        <property type="entry name" value="PRK00595.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01023">
        <property type="entry name" value="rpmG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43168">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L33, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43168:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL33C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00471">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00582">
        <property type="entry name" value="RIBOSOMAL_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 7" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1732175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="UAM91418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="64" mass="7516" checksum="612C2540EE6E32D3" modified="2022-08-03" version="1">MAKNKGTRILITLECTECRTNANKRSAGVSRYLTQKNRRNNPQRMELKKYCPHCNKPTIHKEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1H215</accession>
    <name>A0A8K1H215_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypothetical chloroplast RF88</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ycf88</name>
        <name evidence="1" type="ORF">QTG54_017138</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="2"/>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2021" name="Front. Plant Sci." volume="0" first="0" last="0">
            <title>Chloroplast Genomes for Five Skeletonema Species: Comparative and Phylogenetic Analysis.</title>
            <authorList>
                <person name="Liu S."/>
                <person name="Xu Q."/>
                <person name="Liu K."/>
                <person name="Zhao Y."/>
                <person name="Chen N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CNS00100</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MW679506">
        <property type="protein sequence ID" value="UAM91445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_010200851.1">
        <property type="nucleotide sequence ID" value="NC_058701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1H215"/>
    <dbReference type="GeneID" id="68637972"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="2" id="KW-0934">Plastid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1732095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="UAM91445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="131" mass="15551" checksum="A16290305E730AD9" modified="2022-08-03" version="1">MARLELTLNFPKSFQIKTFNVKSEKKLSSLAKLILQSVQFKHFYYVRDDISYLLKSNPIERDFLLQALYSIVISLQNNLSINFFDMWIYEVYINKVSSHNKFMNEKSQNLEADEYITIKIAYGFNVSQEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XS02</accession>
    <name>A0AAD8XS02_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cupin-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016970</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000072">
        <property type="protein sequence ID" value="KAK1732340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XS02"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051260">
        <property type="term" value="P:protein homooligomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003131">
        <property type="entry name" value="T1-type_BTB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF100">
        <property type="entry name" value="JMJC DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02214">
        <property type="entry name" value="BTB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="2">
        <location>
            <begin position="358"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="474"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="649" mass="73636" checksum="CBFD81986240B27C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSU6</accession>
    <name>A0AAD8XSU6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Myosin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_016220</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000054">
        <property type="protein sequence ID" value="KAK1733082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00124">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.240.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140:SF845">
        <property type="entry name" value="MYOSIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3 6" id="KW-0518">Myosin</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myosin motor" evidence="9">
        <location>
            <begin position="222"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="170"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="295"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="369"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="421"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="905"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="6">
        <location>
            <begin position="933"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1460"/>
            <end position="1487"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1264"/>
            <end position="1401"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1557"/>
            <end position="1633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="82"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="178"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="300"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="377"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="421"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="398"/>
            <end position="405"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1733082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1668" mass="187665" checksum="F5C043CE7F96050B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTM1</accession>
    <name>A0AAD8XTM1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AP2/ERF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_015962</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000050">
        <property type="protein sequence ID" value="KAK1733403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTM1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51032">
        <property type="entry name" value="AP2_ERF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="26"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1733403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="83" mass="9567" checksum="4B3FFC30A3D4B2AE" modified="2024-05-29" version="1">MKKCIDLSDVPPQLPIKSSRKNGSSKYQGVSFDKGWNKWRARIKIDGKSKFIGSYDSEEKAAIDYARAKFKYKEDHDLPLAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XU52</accession>
    <name>A0AAD8XU52_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015776</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000048">
        <property type="protein sequence ID" value="KAK1733488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XU52"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="502"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="729" mass="82753" checksum="2337F5226C003540" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XU54</accession>
    <name>A0AAD8XU54_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Galactose oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_015850</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000049">
        <property type="protein sequence ID" value="KAK1733435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XU54"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="317"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="638"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="339"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="355"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="389"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="401"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="423"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="435"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="662"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="688"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="719"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="732"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="775"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="803"/>
            <end position="819"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1733435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1005" mass="109773" checksum="08B190A076AF0998" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUB2</accession>
    <name>A0AAD8XUB2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015813</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000048">
        <property type="protein sequence ID" value="KAK1733525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUB2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="115" mass="13254" checksum="99D5A45444A9ABB3" modified="2024-05-29" version="1">MGRSCDAQKRHTPTFKLDDHLSLGTMHPNNDEIRQTAVFDDIFDVDDLPAATSQGNLPDTDDEDLLMEEINPTGYQPNEEAQTSPHSTNPVQDSDEEMARRRRRRTWYSRHQLSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVV2</accession>
    <name>A0AAD8XVV2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014944</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVV2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="404" mass="46360" checksum="8086C98C19019B2D" modified="2024-05-29" version="1">MYWLGLDEEARDAATILGYNEELWDGDDDEDPPIFGTPFANLHSREKEAARYLNMVDQFPLFHSNGVPWSSLNVPAQDAAALLGYDEVLWNQNYPIPILMNRTQRLDAVPSRLLRTIRFLGLDHYYDLSRLQTKNGNYNTPRYIDNTNMELVKKQLQDLADQKIFLYITTHMSDLHRSALEYVWPYAVNASNLLSQADVLLHYSTTTSAEEQEEQLSPHHLMKTAFGPSGNNVTILHSRQNPGYQEGAIQAISDALENNWFTPYDWIIRVNPDVIIRNDTWIIHQMLDKEKVGAILVDCGDKFLNSAKYAKVHTDFSIFQPKYVQVPEEAKRIVNAEKHFSQIIEEVWTTGRAAILPDNDPNHGICRVRGDKSSVVHDHEWLDGMIQCFNQGIYNFTKCNSLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVY8</accession>
    <name>A0AAD8XVY8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Amine oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_014955</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVY8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050464">
        <property type="entry name" value="Zeta_carotene_desat/Oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923:SF46">
        <property type="entry name" value="AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042005542" description="Amine oxidase domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="domain" description="Amine oxidase" evidence="3">
        <location>
            <begin position="126"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1734448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="646" mass="70392" checksum="F4B47D7FB0904158" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW18</accession>
    <name>A0AAD8XW18_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">proline--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Prolyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_014596</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>tRNA(Pro) + L-proline + ATP = L-prolyl-tRNA(Pro) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XW18"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017101">
        <property type="term" value="C:aminoacyl-tRNA synthetase multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00778">
        <property type="entry name" value="ProRS_core_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000023">
        <property type="entry name" value="Proline--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.30">
        <property type="entry name" value="C-terminal domain of ProRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01571">
        <property type="entry name" value="Pro_tRNA_synth_type3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004499">
        <property type="entry name" value="Pro-tRNA-ligase_IIa_arc-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016061">
        <property type="entry name" value="Pro-tRNA_ligase_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017449">
        <property type="entry name" value="Pro-tRNA_synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033721">
        <property type="entry name" value="ProRS_core_arch_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="uS15_NS1_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000738">
        <property type="entry name" value="WHEP-TRS_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00408">
        <property type="entry name" value="proS_fam_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43382:SF3">
        <property type="entry name" value="PROLINE--TRNA LIGASE, CHLOROPLASTIC_MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43382">
        <property type="entry name" value="PROLYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09180">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00458">
        <property type="entry name" value="WHEP-TRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00946">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00991">
        <property type="entry name" value="WHEP-TRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64586">
        <property type="entry name" value="C-terminal domain of ProRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="S15/NS1 RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51185">
        <property type="entry name" value="WHEP_TRS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041937544" description="proline--tRNA ligase" evidence="10">
        <location>
            <begin position="24"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="domain" description="WHEP-TRS" evidence="12">
        <location>
            <begin position="76"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="11">
        <location>
            <begin position="195"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="119"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="125"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1734723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="661" mass="74429" checksum="D45E0246204314AB" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW67</accession>
    <name>A0AAD8XW67_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Magnesium-chelatase subunit ChlD, chloroplastic</fullName>
            <ecNumber evidence="3">6.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Mg-protoporphyrin IX chelatase subunit ChlD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_014816</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; chlorophyll biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Mg-chelatase subunits D/I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.6.1.1" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000038">
        <property type="protein sequence ID" value="KAK1734568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XW67"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016851">
        <property type="term" value="F:magnesium chelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01451">
        <property type="entry name" value="vWA_Magnesium_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.80">
        <property type="entry name" value="Magnesium chelatase subunit I, C-Terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041702">
        <property type="entry name" value="BchD/ChlD_VWA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052989">
        <property type="entry name" value="Mg-chelatase_DI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000523">
        <property type="entry name" value="Mg_chelatse_chII-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35023">
        <property type="entry name" value="CHELATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35023:SF1">
        <property type="entry name" value="MG-PROTOPORPHYRIN IX CHELATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01078">
        <property type="entry name" value="Mg_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="9">
        <location>
            <begin position="629"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="442"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="472"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="511"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="537"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1734568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="821" mass="90889" checksum="0609C0D638A30540" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWT6</accession>
    <name>A0AAD8XWT6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013983</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWT6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="196" mass="22241" checksum="51FF37161B744E90" modified="2024-05-29" version="1">MKRRRSMDSDDLPSPRKRATSSLATIILCIISCKLLVGVHAFAPQPSKQTCILHRPQNLPFNHITRLHASIDDVDDDESDALLNELRDKKKKAFGKDLPSSDELEQAAKNAENDFLAAMLEQSQTFKEIKSEKGGDAAVSEFRRRIQEGDEAQRLEDAKAAAEESGEESMDKKWFVQQMEGIMEEIEEEFEDDSWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXN7</accession>
    <name>A0AAD8XXN7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">UAA transporter family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_013756</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXN7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005459">
        <property type="term" value="F:UDP-galactose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005460">
        <property type="term" value="F:UDP-glucose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778:SF18">
        <property type="entry name" value="SUGAR PHOSPHATE TRANSPORTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08449">
        <property type="entry name" value="UAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="411"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="123"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="249"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1735593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="447" mass="49204" checksum="65707A67BE7770CB" modified="2024-05-29" version="1">MYPHIEEKKDDCDDDVIASASTTKASAPHYPHHTITSSNQPNNETNKSRPLLLLLCATGITSCYLWYGTVQEHLFQIDNANSGDDKQSITLFLLATGTFSSFLLALVWIVIGPLLLAQTTDRTSGKENSPRDHGQVQDNGQLNHPLLALTSITYLSAMAASNESLHYVSYPTCVLAKSSKLIPTMVVGWLVDKYRSYWRIGIQQNNNSSTSSSTNHKGINGMEWLGAALITIGILSFQYIQLQKQSNDSSHHPHGGDGEDKEEKGDSPYGLALLGLSLFMDGLLGACQSTLKQTHHSSSSSTTFRPPSAMETMLYINLYATLILIPCSYYAGQFQHGMSMLFPSTDTIANTEAEHTSKLLLQLNLSASLGQVFIFLTIHHFSPLTCTTVTTTRKFFTILLSVYKFGHVLDVWQWCSVGLVFGGLYLEIVAKFIGEKGDGDGKKQKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYC7</accession>
    <name>A0AAD8XYC7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Protein HIRA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_013300</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat HIR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000417">
        <property type="term" value="C:HIR complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0006351">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="HIR1-like"/>
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        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
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        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13831">
        <property type="entry name" value="MEMBER OF THE HIR1 FAMILY OF WD-REPEAT PROTEINS"/>
        <property type="match status" value="1"/>
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    <dbReference type="PANTHER" id="PTHR13831:SF0">
        <property type="entry name" value="PROTEIN HIRA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Hira"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
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        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
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        <property type="match status" value="2"/>
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        <property type="match status" value="3"/>
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        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3 9" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="74"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="272"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="414"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="Protein HIRA-like C-terminal" evidence="11">
        <location>
            <begin position="989"/>
            <end position="1216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="11"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="118"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="194"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="465"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
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            <begin position="527"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="577"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="735"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="848"/>
            <end position="870"/>
        </location>
    </feature>
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        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
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        <location>
            <begin position="142"/>
            <end position="153"/>
        </location>
    </feature>
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        <location>
            <begin position="201"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
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        <location>
            <begin position="241"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
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            <begin position="478"/>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="855"/>
            <end position="864"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00007306"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1736164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1285" mass="136831" checksum="9D960047E2EB0F97" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZ29</accession>
    <name>A0AAD8XZ29_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine aminopeptidase (Family S33)</fullName>
            <ecNumber evidence="2">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013234</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000030">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="49"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="325" mass="35735" checksum="F09C622BE9C6EFF5" modified="2024-05-29" version="1">MSSYLSKEAMIEAAGPPSLPDGFIVDSFTNSRSQSIFTIHLPRADMSVPPKAMFVLVHGTAEHCCRKGYIGLYESLSKAGVDVYSMDNHGNGRSDGEPRGYTESIDDYVEETIEYIQLVQKSKYEQDQCPPLVVMGHSLGGCIAVMTALKMGSGKSDISLILSSPALGVDMNLELKVQKFFAPVIDFVCPKARIVDVVDAVEMSRNEEAVKAYIDDPLCPIGKMIAHTAIATDKAFDYAKQRRGEIYCPTLMLHSPDDKCTSQKASEDFFANIGTALEDKRYLKLNGMYHETLEEPETERIVKSIVTFVASGGKEFVEDVGMVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZ87</accession>
    <name>A0AAD8XZ87_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013221</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
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            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZ87"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
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        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="388"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="479"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="508"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="573"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="951" mass="107139" checksum="1646DD79A0CD52C6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y044</accession>
    <name>A0AAD8Y044_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NAD-dependent protein deacetylase</fullName>
            <ecNumber evidence="6">2.3.1.286</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_013045</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N(6)-acetyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-acetyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:43636"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17154"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="ChEBI" id="CHEBI:83767"/>
            <dbReference type="EC" id="2.3.1.286"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.286" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y044"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017136">
        <property type="term" value="F:histone deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017328">
        <property type="entry name" value="Sirtuin_class_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF6">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037938">
        <property type="entry name" value="SIR2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6 8" id="KW-0520">NAD</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 6 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="11">
        <location>
            <begin position="63"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7 10">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="101"/>
            <end position="103"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="174"/>
            <end position="177"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9 10">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9 10">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9 10">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9 10">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="292"/>
            <end position="294"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR037938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR037938-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR037938-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR037938-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1736445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="339" mass="37578" checksum="E7CD608DE00E4FDE" modified="2024-05-29" version="1">MNFRTLATSSTSFLCTCASNNVAFINTCTSLRSFCCQNKLRFYCKHSRSTPTTQLYQTRDASSLPEKTTIETIAESLRSNAFKKVLVVSGAGVSVSAGIPDFRSPGSGLYDNLHKYDLPYPEAIFDVDFYNQNPQPFVTLAKEIWPGVNYRPTLTHCFFSLLDKKGILRRVYTQNIDGLEAVAGVTEEKLVECHGHFRSSACIKCRTPFDAEVCQSTMIEQGEAPKCNSCGGSVKPDIVFFGEVMPSRFSDLVHYDVASSDLVIVLGSSLMVAPVCNIPDWVKSNVPRLLMNRDLVGTFGKVNDVFMEGDCDDSVRELCRLVGWEDELDAIYASTHSQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y051</accession>
    <name>A0AAD8Y051_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">fructose-bisphosphate aldolase</fullName>
            <ecNumber evidence="6">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_012735</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class II fructose-bisphosphate aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y051"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00946">
        <property type="entry name" value="FBP_aldolase_IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000013">
        <property type="entry name" value="Class II fructose-bisphosphate aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006411">
        <property type="entry name" value="Fruct_bisP_bact"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00167">
        <property type="entry name" value="cbbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01520">
        <property type="entry name" value="FruBisAldo_II_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006628">
        <property type="entry name" value="PRK09197.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30559:SF0">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30559">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00602">
        <property type="entry name" value="ALDOLASE_CLASS_II_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00806">
        <property type="entry name" value="ALDOLASE_CLASS_II_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="10 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042293858" description="fructose-bisphosphate aldolase" evidence="11">
        <location>
            <begin position="16"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1736713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="400" mass="42732" checksum="1E06614F8A29C266" modified="2024-05-29" version="1">MKLAIATLLIGSAAAFAPAATPMRNSALSMSTETTTEKAFAKLPASIKPGVVTGPALVDLLDAAKEQGYAIPGVNIVGTNSINACMEAAASYGGPIMVTFSKGGGQFIAGKSVNNDADQASIAGTIAGAKHVHEVAALYGVPVVLHTDHCQKAWLPWIDGLLTASEEHFAATGSPLFSSHMLDLSEEPLEENIGICKDYLEKFAKVGILLEFELGVTGGEEDGVDNTDIDSSRLYTQPEEVFYAYEQLSQVENGAFTCAASFGNVHGVYAPGNVDLQPKILMNSQAYIKEKIGSDSDKPMKFVFHGGSGSDVSDIQEAIGYGVIKMNIDTDTQWAFWDGIRAYEAKYHDYLQGQIGNPEADDKPNKKYYDPRMSLRAGEEAMAARLVKAAEDLKCVNVLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0C1</accession>
    <name>A0AAD8Y0C1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="8">3.6.4.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_012742</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0C1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47960">
        <property type="entry name" value="DEAD-BOX ATP-DEPENDENT RNA HELICASE 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="202"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="480"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="70"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="640"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="678"/>
            <end position="694"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1736720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="694" mass="74360" checksum="581B14B561957D9B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1G1</accession>
    <name>A0AAD8Y1G1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011942</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1G1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47026:SF2">
        <property type="entry name" value="FLAGELLAR ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47026">
        <property type="entry name" value="PIGMENTOSA GTPASE REGULATOR-LIKE PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="223"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="298"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="463"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="48"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="228"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="260"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="618" mass="70124" checksum="19AF4EDC3BE7A20F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1K8</accession>
    <name>A0AAD8Y1K8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatidylinositol-4-phosphate 5-kinase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1K8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23084:SF263">
        <property type="entry name" value="MORN REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23084">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="432" mass="47919" checksum="D586FC02ED94FFBC" modified="2024-05-29" version="1">MAAEGDRIISFNYTDVADEIPLGATHVIISIRVIPANAFDGHPSIIEVICGPDVERVGDYAFAFCPFLRRVIMPGVEIVEHAAFIGCEALTDVECGKLEIIGDCAFEGCESLMSINLPSVKIVVGDSFLHCFGLTDVTFSNKLESLGYASFADCTALKRITIPLKDGIIAADDLFSGCGEKLERVDLIEGVVLHETIAALLLEEWRNDMYEEIDSINQILLTASAGFYHYDMDHHDDGGKARAIRTWIRSVLRKIIHYKAEHQRIVDEAATYLQLALPRDIVMKNVLPSLELPSYTFEGEESEGGMDGEMTSADGILYEGDWKNGKLHGEGKMTYANGNVYDGYWRDDKKHGEGKYTSDGYWKDDKRHGEGILITYADGIVYDGYWRNDKPNRKSFAKRLLRSAVNSAIGAALGLAEDPVILLCIQIERSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y245</accession>
    <name>A0AAD8Y245_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011565</name>
        <name evidence="2" type="ORF">QTG54_011568</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y245"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="285" mass="31860" checksum="F15EE1B4FD1521D1" modified="2024-05-29" version="1">MAAEGDNITWYNYTGAEVIPHDATHVTVSARVIPAEAFSRNRNIVEIIGPSVEKIEARAFNKCPSLRRVIMSGVEIVEQCAFTECVALTDVECDKLEIIRYAAFNGCTSLGSINLPSVRIVEGDTFNDCEALTDVNFGSKLERIEEMAFDDCPSLERITIPLKDGIITHDGIFQGCENLKHVDIVEEVVLHETIAALQLEEWRNDINEEIDSINQILPTTPAGRWGHDVGDKARAIRTWIRLVLGKIVRYKAQHQHLLDEAATTLQLALPKDIVMKNVLPFLELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2W1</accession>
    <name>A0AAD8Y2W1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2W1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1660.10">
        <property type="entry name" value="EreA-like (biosynthetic domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007815">
        <property type="entry name" value="Emycin_Estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052036">
        <property type="entry name" value="Hydrolase/PRTase-associated"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31299">
        <property type="entry name" value="ESTERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31299:SF0">
        <property type="entry name" value="ESTERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05139">
        <property type="entry name" value="Erythro_esteras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159501">
        <property type="entry name" value="EreA/ChaN-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1738007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="345" mass="40315" checksum="E3B23618187A5E5D" modified="2024-05-29" version="1">MYSAWAEGRDLIEWMVVCNVAQLMRGRDNFVDYCGLDIGGFYSDWTHPISMIQRYIKQHFPHFERNWSQQINPLLYALGTSKARYNYQHVLTATEKNKLALLLDELVNMMSSKRDELEGDLDFEWTRQSAISMQLAENYYRNYEHMSTDDITKKFEGLNGREIAMANNILWRLNLDCSNERSRSEQKKMIVINHAIHTKTATQYQDEIWGHFVPMGQMVKQMLNAKSAKEGNKQTVFNIGMIYGGGTFWDKWQRPNERIVAKIPPPKDDGLEATMKKVSEKSGIKNFFLHWETAPSDAFVYLQSVTTIRENDYFIRAFPLEWNGCIYLDHVTHATPDDGVKYRMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y357</accession>
    <name>A0AAD8Y357_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional accessory protein Tex</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011220</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y357"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3500.10">
        <property type="entry name" value="Tex N-terminal region-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.310">
        <property type="entry name" value="Tex RuvX-like domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="entry name" value="YqgF/RNase H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041692">
        <property type="entry name" value="HHH_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050437">
        <property type="entry name" value="Ribos_protein_bS1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055179">
        <property type="entry name" value="Tex-like_central_region"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023323">
        <property type="entry name" value="Tex-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032639">
        <property type="entry name" value="Tex_YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006641">
        <property type="entry name" value="YqgF/RNaseH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10724">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10724:SF10">
        <property type="entry name" value="S1 RNA-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12836">
        <property type="entry name" value="HHH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17674">
        <property type="entry name" value="HHH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22706">
        <property type="entry name" value="Tex_central_region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16921">
        <property type="entry name" value="Tex_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00732">
        <property type="entry name" value="YqgFc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158832">
        <property type="entry name" value="Tex N-terminal region-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="565"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="642"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="664" mass="71915" checksum="34A9A9EC32C6BB32" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y374</accession>
    <name>A0AAD8Y374_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">dCTP pyrophosphatase</fullName>
            <ecNumber evidence="3">3.6.1.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011018</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.12" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y374"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047840">
        <property type="term" value="F:dCTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006253">
        <property type="term" value="P:dCTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042262">
        <property type="term" value="P:DNA protection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11537">
        <property type="entry name" value="NTP-PPase_RS21-C6_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1080">
        <property type="entry name" value="MazG-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052555">
        <property type="entry name" value="dCTP_Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025984">
        <property type="entry name" value="DCTPP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46523">
        <property type="entry name" value="DCTP PYROPHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46523:SF1">
        <property type="entry name" value="DCTP PYROPHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101386">
        <property type="entry name" value="all-alpha NTP pyrophosphatases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042076588" evidence="2">
        <location>
            <begin position="29"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="314" mass="35113" checksum="F766B18D15B52BBF" modified="2024-05-29" version="1">MGFFLIISCTITTTLLLLTSTMPSTAFTQPITSASPKSILTINSAAMIGRVDFAYLRDNCATTNDTKISEVEPNNNSIATIRDLIFELGAITGMICTTFMSVPHDFNRTDDESRPSPNDDPFWTEPSPQKEELSRQLGELFLHLFRISASCHLDLCTCVLKKIELNGQKYPVELCKGKAGKYTDYSEHTGITTTEGQCTINTPTKASSNDMEDTTTVEGITILIRNFADERLWHRHHCPRNIALAMMGEVGELAEIFQWKKDEGELDMKMTEKELDKVGQEVADVTIYLLRLADVCHVQLGDEARKLIEACEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3W2</accession>
    <name>A0AAD8Y3W2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">S51 family peptidase</fullName>
            <ecNumber evidence="6">3.4.13.21</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_010404</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S51 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.13.21" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3W2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005320">
        <property type="entry name" value="Peptidase_S51"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20842:SF0">
        <property type="entry name" value="ALPHA-ASPARTYL DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20842">
        <property type="entry name" value="PROTEASE S51 ALPHA-ASPARTYL DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03575">
        <property type="entry name" value="Peptidase_S51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1739088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="525" mass="57201" checksum="6DE84C34FA756621" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4Q2</accession>
    <name>A0AAD8Y4Q2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4Q2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042227129" evidence="1">
        <location>
            <begin position="20"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="351" mass="38453" checksum="580719AA00115681" modified="2024-05-29" version="1">MMMSRTGYLLLLLAAPAIAAKKGGTAGPVNASSSGNVKPLQFSSAIQSYTIFDKSALTSPEYASPRRKFLPRFRTGLSAERRARDVILDEERRGLLQDDDSVSSGGSWAEASAAADEKKKKAIEKRVEAAHDAAVSGYDRRVAAKKSAAAAKAASTSQYQFVGVVNDGKGAKGKVTWYARKKPTNSKWSVRLVHVNRDAVLRDLFAKGKVDIFGKYTNEGLDKAAFAAADNGGDAVTDADENQQPGMKPLVKGNYYVKQRSWKNLWNFSPKRMFTTPSGSFWRERRISPGLYTDGTKVYESVYRYRDGKNGLKPVAKLSDFLASPGLGYEEKMKVVQRLKGGDEPDLVVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5Q7</accession>
    <name>A0AAD8Y5Q7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Chlorophyll a-b binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_009774</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated. Energy is transferred from the carotenoid and chlorophyll C (or B) to chlorophyll A and the photosynthetic reaction centers where it is used to synthesize ATP and reducing power.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fucoxanthin chlorophyll protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5Q7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030076">
        <property type="term" value="C:light-harvesting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="8" id="KW-0157">Chromophore</keyword>
    <keyword evidence="7" id="KW-0437">Light-harvesting polypeptide</keyword>
    <keyword evidence="5" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042138949" evidence="9">
        <location>
            <begin position="16"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1739231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="222" mass="23548" checksum="886F87A8D9FD155E" modified="2024-05-29" version="1">MKLTLFSALAGSAAAFAPAQTSTSTTALNAEKEMSKALPFLPRPKLLDGSLPGDVGFDPFNLGGGDKASLINMREAEIKHGRLAMLAAVGWPIAELFDRQIAGAFGLQSALTSTGASPSLLNGGLDKIEPDYWVIVASIAGLAELSSKETKEEKGKSYIAGDCGFDPLGLFPQDKEGMMAMQTKEIKHSRIAMMAVLGYAAQEALFRSPVTEETPMFFKSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y661</accession>
    <name>A0AAD8Y661_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Thioredoxin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_009954</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43601">
        <property type="entry name" value="THIOREDOXIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43601:SF32">
        <property type="entry name" value="THIOREDOXIN-LIKE 2-2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="180"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="92"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="357"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="793"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="957"/>
            <end position="1616"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="737"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="10"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="128"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="149"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="370"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="382"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="979"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1003"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1059"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1116"/>
            <end position="1125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1131"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1161"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1172"/>
            <end position="1186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1191"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1229"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1259"/>
            <end position="1287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1305"/>
            <end position="1314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1336"/>
            <end position="1358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1407"/>
            <end position="1429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1483"/>
            <end position="1507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1521"/>
            <end position="1536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1605"/>
            <end position="1616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1739411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1616" mass="175715" checksum="DDF35F717C15FFCE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y671</accession>
    <name>A0AAD8Y671_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009503</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y671"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31424">
        <property type="entry name" value="PROTEIN CBG23806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31424:SF3">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="373"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="456"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="408"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="623" mass="70009" checksum="3C33F5AA4D202EE4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6D1</accession>
    <name>A0AAD8Y6D1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyl-lipid omega-3 desaturase</fullName>
            <ecNumber evidence="4">1.14.19.36</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_009292</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.36" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6D1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32100">
        <property type="entry name" value="OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042047278" evidence="2">
        <location>
            <begin position="23"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid desaturase" evidence="3">
        <location>
            <begin position="139"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1740342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="436" mass="49075" checksum="6C4A211623898CBD" modified="2024-05-29" version="1">MKNNSIVKGALATTLLWTAADSFAPVYQSTQQQASATSLRSSILADDVIKGTTSNDPLSTVADMNDEDIAAMMRNDNPPLPGTIMKMLPKDTFQVDTATSLMYAGLDVAAVVGSMSFLYAVVQSDFYNGLPIAGQALTVAPLQILTGFAMWCTWCIGHDAGHGTVSKSTKFGKGINRIIGEITHSMICLTPFVPWALSHKKHHLNHNHLEKDFSHQWYIREEAGDLHPLIQASYYIRMVFFPFLYFIYLFTGIPDGGHVLFYGRMWEGESMKDKLDGALSVAVSVATAGTLWHNMGTSDFAVVCMAPWTVMGFWLFMVTYLQHHSDDGKLYTDDTFTFEKGAFETVDRDYGELVNKLSHHMMDGHVVSTTCIHHLFFTKVPHYRLHAATQALQKGMKERGQDHLYKQIDTPDYTQEIVKQYYNNWFYVNEKNIVRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7D1</accession>
    <name>A0AAD8Y7D1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008378</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7D1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1741126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="191" mass="21204" checksum="D94674B978BDB595" modified="2024-05-29" version="1">MVIIVASAAPTIGVSLGASSVSIEYESSGGAGNFWAYASTERTSVWYNYDNVYNETTGEYDQVMNRTLYDGVGEHSWIHIHARKYIWFDQASQSPELLATEALLNYRGGVEPLYAADNTNGTSLFPQGSTVLTEYNYQYDYNDQCKSVPVPDSPWGDTKWVCKSNCPPEQLSNMSYAGTCANAAEDIRLLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7R4</accession>
    <name>A0AAD8Y7R4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008314</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7R4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33099">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33099:SF7">
        <property type="entry name" value="MYND-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="367" mass="40054" checksum="BB2DDC4AD8765999" modified="2024-05-29" version="1">MSSPSNAVADIGILANGHRPNDDGSTVNEPEMIITSRRDVYGSMAHGTDLCGNCCFGDIADGSTTSPALPPIVGLRISGVGNVPLPISDEHAGKIKSRITNEEKGGKKIISLYEIEACKIKLLNPMWNESLGNLLDTVAYKLGVNPSHLSARPKKLMYMEKGGCINRRRDDEEDGNVLGSLIIQLPSQFTGGELTIYNSSVEDDKDEESFKFTLGAGEEATYSCHFACHFSDCEYEMAKLRSGSRLLLCYSLRYKEVDPMPTAGLITETISPLTCSLGGLPPADRIVVIPLEKEYRIHSLANSGINALSRAHRQKAEALKAAGTDWELRIVNAKLEHTCGYYGFEDCNNNSSVIEIYDELASVSQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7Y9</accession>
    <name>A0AAD8Y7Y9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7Y9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="164" mass="17762" checksum="E8AE30635123686E" modified="2024-05-29" version="1">MAAANVSSKRRRLLGDASLEDFISCLLSDLPSGILTHVANYLDAPSRALFAAALATNQNAAASDERNSAIVGNEWTTLDFGDIEEDLAARLSDGDISAVLLCIDAVNRLKRLKLTNCYNITGVGLEPLRGSTTIEQIDLSLFYDRKHPDFCPAPLISCATMKCW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8C5</accession>
    <name>A0AAD8Y8C5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nuclear distribution gene C family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_008736</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8C5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06467">
        <property type="entry name" value="p23_NUDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037898">
        <property type="entry name" value="NudC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025934">
        <property type="entry name" value="NudC_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356:SF17">
        <property type="entry name" value="CS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356">
        <property type="entry name" value="NUCLEAR MOVEMENT PROTEIN NUDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14050">
        <property type="entry name" value="Nudc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="3">
        <location>
            <begin position="185"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="87"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="321"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="118"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="154"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="328"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1740641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="363" mass="39488" checksum="59D5D0744F87D72B" modified="2024-05-29" version="1">MSSPALAPLLTPAELQKFEGPLIAMAQQANGSLPKLLTAFFSFLHRRTDFYCILPEDGGGGGRNVGFKEGQAEQILLATFRQFPLRRVGPAPKSKSPPSPQAVVSGASKATKGTVVSEKAKAETASDKGKKIAAADDVKTKDDPGTKDKEKTTDTTTKPAAKPATKETTIRYTDVGKQIPIGNGGSTSRYVWTQTLEEVTVHIPIPNGTRAKDLNVKIDAHSLSVKRKDGDHASLTPVEGIFFARIRPDECTWTIESSSAESQSMTTLQLTLDKIQRTWWDIVISGDNPLIDTTMVDSSRHIETYDEKTQAQIRRIIHDQRQERLGLSSSDSSPKTSSGKIPPMPSGVEYIDGETLDKATIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8G8</accession>
    <name>A0AAD8Y8G8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LSm14 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_007329</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8G8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033962">
        <property type="term" value="P:P-body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034063">
        <property type="term" value="P:stress granule assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01736">
        <property type="entry name" value="LSm14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025762">
        <property type="entry name" value="DFDF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019050">
        <property type="entry name" value="FDF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025609">
        <property type="entry name" value="Lsm14-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025768">
        <property type="entry name" value="TFG_box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586">
        <property type="entry name" value="SCD6 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586:SF0">
        <property type="entry name" value="TRAILER HITCH, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12701">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01199">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01271">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51512">
        <property type="entry name" value="DFDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51536">
        <property type="entry name" value="TFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DFDF" evidence="3">
        <location>
            <begin position="164"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="TFG box profile" evidence="4">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="85"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="231"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="TFG box" evidence="1">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="193"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="231"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="253"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="283"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1741756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="310" mass="33661" checksum="2DEB29038C28407E" modified="2024-05-29" version="1">MASNPLIGNRISLISKKNIRYEGVLYSINESDATVALQDVKSFGTEGRELLDTTGQTNFVPPQDTVHTYLLFRGQDIKDLHVHEKQGTPAAAADTTPAKEEAPPAAAVETKKEESISEPETKKETSTKAKTESKENKPNAKKGGNQKKNMVGSGASLLNKKARGAKGDQIKVGEDFDFESNLEKFENTKISADDEEEDDIQEEDTNVYSAGDFFDSISCDAIDKANGIDNRLRGADERNLNLDTFGATSLGNNRRRYGGRGRGRGGRGRGRGRGRGGRGGGSRSNNSRNYEGGPAPRQNNRWKESSTTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8R7</accession>
    <name>A0AAD8Y8R7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arsenical pump-driving ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007316</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8R7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043529">
        <property type="term" value="C:GET complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071816">
        <property type="term" value="P:tail-anchored membrane protein insertion into ER membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02035">
        <property type="entry name" value="ArsA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002933">
        <property type="entry name" value="Putative arsenical pump-driving ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025723">
        <property type="entry name" value="ArsA/GET3_ATPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016300">
        <property type="entry name" value="ATPase_ArsA/GET3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00345">
        <property type="entry name" value="GET3_arsA_TRC40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10803">
        <property type="entry name" value="ARSENICAL PUMP-DRIVING ATPASE ARSENITE-TRANSLOCATING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10803:SF0">
        <property type="entry name" value="ATPASE GET3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02374">
        <property type="entry name" value="ArsA_ATPase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="1">
        <location>
            <begin position="61"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="1">
        <location>
            <begin position="454"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="810" mass="87625" checksum="47E4DD1152C2CCD7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8Y6</accession>
    <name>A0AAD8Y8Y6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008472</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8Y6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="198"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="275" mass="31063" checksum="ED109CEFC41E9B0C" modified="2024-05-29" version="1">MAPKQIVDFDERDYDEMIELSTLLGRECIINIAPQSQDCGCELGEAQSSSSSVDRKSTIMTPRPRKELPPSILRHRLHPRQEQPPHWPKLQRVHFADERPRKISSSPPSVITAIYYRPRTPIADVSSLYYSALDVKNFKREFRALLRSQELARQRFERLSPTADTTDTDVACPTVQHHDNSFWRSKVSRWSAQTKEVTSAATASDPPSSGGNEESNQYITDCDDDVDYTPSSQGGIFSSVFDVAREAVSLLGTSSSSAYYYQKDSTLYLFKKNAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y922</accession>
    <name>A0AAD8Y922_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_007752</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y922"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF127">
        <property type="entry name" value="ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="3">
        <location>
            <begin position="96"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="229"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1741274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="311" mass="34889" checksum="02DD6F4EC5DEA974" modified="2024-05-29" version="1" fragment="single">HVEQHIEDSPCSYIQWRFKDGFDKEKIESEAFRIRITPQEQKAIDDYNLEGIWSRRLRAGVPEYEIKKKHVREKDNIYVSKDELLAMGFKHLLRQTDEKIASKEAGLDLRPVTTSEIQTHLDDFGLAQEFGTYGKIRGLSGGQKVKLVLAAAMWNCPHLLVLDEPTNYLDREALGALSAALNEWGGAVLMISHNKEFYGSVCKEEWIVADGKVDVKGDSDEREMKAVARKKESKKEKSADAIVESAGGNTNADGDKYKDATTNFWGKAVSKKEARNYDKAKKKGDVAAMRKILAIPKGKVMPGQEELGDGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAW3</accession>
    <name>A0AAD8YAW3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006775</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAW3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="235"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="268"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="166"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="450" mass="48129" checksum="094D2113258EEB60" modified="2024-05-29" version="1">MAPNAASSSSTTMDPLTATTKMAKAIMSAPTGNGKLVCTILSAYDLPDAEGVVPESVTMSYREATGRGNGYNEISTGPPAAKHKDHNNSFKFGGPDSAANQLTISAPLPVLFESTVTFTLKYPDASKNLTSTCTIHKTLRVNDTQWLILNLDPVSDSAGTRTPLKSSASRISTSSSSNEQQPTLRLKLRLEGPYRPEIAAVVNLMNGWFTAVDVISDNTVGFVSDIPKNVPAVKLLLVPTVPLATVAIGALPILGGIMIIGIPFFLPIFLIVLTLGLSLGAIGSSVYFSTRSGRTRIQHVAEPSYQTFLMTKTGQRIIYDVGPRPSPQSLAHAVLPSDMIGKLIVSLVIDAIGSASYLIPLAGEGFDLTWAPMSMILVGALYDDVMPNLKYIALIEELLPFTDFIPSATLGWVKEFGPNIIDEAKGRMGDAKRAGRRERDALANLHLSRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAX8</accession>
    <name>A0AAD8YAX8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">40S ribosomal protein S6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_006790</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAX8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001377">
        <property type="entry name" value="Ribosomal_eS6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014401">
        <property type="entry name" value="Ribosomal_eS6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018282">
        <property type="entry name" value="Ribosomal_eS6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11502">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01092">
        <property type="entry name" value="Ribosomal_S6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002129">
        <property type="entry name" value="Ribosom_S6_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01405">
        <property type="entry name" value="Ribosomal_S6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00578">
        <property type="entry name" value="RIBOSOMAL_S6E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="227"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1742225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="242" mass="27632" checksum="C961C594A0FBD399" modified="2024-05-29" version="1" fragment="single">LQINISCPSTGLQKVIEIDDEKRLQNFYERRMAQEIDGGVLGDEFAGYVMRITGGNDKQGFPMRQGILVNHRVRLLMHKGHKGYRQRRAGERKRKSIRGCIVSHDIAVLNLAVVKIGDNTIAGLTDDSIPRRLGPKRAQKIRKLFNLTKEDDVTKYIIARTFTNKKGKEVRKAPKIQRLVTPLTLQRKRARKAAKLASVLRNKEDAAAYKKVVAQRLAEQKEARRSLISKRRSTRRSQKIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YB22</accession>
    <name>A0AAD8YB22_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CAP-Gly domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006757</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000793">
        <property type="term" value="C:condensed chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43941">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43941:SF1">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00845">
        <property type="entry name" value="CAP_GLY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CAP-Gly" evidence="3">
        <location>
            <begin position="44"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="119"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="333"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="423"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1323"/>
            <end position="1350"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="268"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="629"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="119"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="166"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="185"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="236"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="337"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="355"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="368"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="423"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1333"/>
            <end position="1343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1742192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1350" mass="146773" checksum="034D4049E1078FFA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBQ5</accession>
    <name>A0AAD8YBQ5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">BZIP transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_006931</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBQ5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14809">
        <property type="entry name" value="bZIP_AUREO-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000837">
        <property type="entry name" value="AP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23351:SF24">
        <property type="entry name" value="ACTIVATING TRANSCRIPTION FACTOR 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23351">
        <property type="entry name" value="FOS TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="6">
        <location>
            <begin position="119"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="BZIP" evidence="6">
        <location>
            <begin position="294"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="66"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="209"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="439"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="306"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="89"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="131"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="236"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="446"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="474"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1742366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="483" mass="52255" checksum="45BBEFE5D76CAE12" modified="2024-05-29" version="1">MISNQEDIASKLLQSSDARIAEAAKRVFSLYSYPAAAMSTFSDAPNNTSSGSVSDEKYSIDIAADQSQDGDHEMSTSYQNGAGGGKHTANITSGPIETTASNEEVFDEAQGGDKKPSSTERLQRSRERNRMHARKTRQRKKEHMQQLQNRADELKLEQIRLKQCINEKNTANILVGLFQTGEDSAAADGSDDTETAVSMDPQVEVLLKRPTEEIPDASKIPELPALILPGQHTKRQSSSSNDGASEDNTPTAAAPAADGEGVTIPEGEQEDGIDYVLLGKDRGSCTPAELDQIRRERNRMHAKRTRDRKRIFMEEMETMIKQLEDENALLQGHMDKLNENNPDENIAAAELLAATAALTPPPTISPELGPVATPSNSLVAGSASATADPLAAATEQPSKGDFLNQIESLLAAAGAFEKNRSQCEVNAISISCAASDVTDQSSYGCEDDHSSHDNRPSKKQRHLEEEDRHASVPKSITTTNLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBR9</accession>
    <name>A0AAD8YBR9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP phosphoribosyltransferase</fullName>
            <ecNumber evidence="5">2.4.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">QTG54_005954</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + ATP</text>
            <dbReference type="Rhea" id="RHEA:18473"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="2.4.2.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ATP phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.17" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBR9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003879">
        <property type="term" value="F:ATP phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13592">
        <property type="entry name" value="PBP2_HisGL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.120:FF:000003">
        <property type="entry name" value="ATP phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000123">
        <property type="entry name" value="HIS1p ATP phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00079">
        <property type="entry name" value="HisG_Long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020621">
        <property type="entry name" value="ATP-PRT_HisG_long"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013820">
        <property type="entry name" value="ATP_PRibTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018198">
        <property type="entry name" value="ATP_PRibTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001348">
        <property type="entry name" value="ATP_PRibTrfase_HisG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013115">
        <property type="entry name" value="HisG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00070">
        <property type="entry name" value="hisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03455">
        <property type="entry name" value="HisG_C-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403:SF8">
        <property type="entry name" value="ATP PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403">
        <property type="entry name" value="ATP PHOSPHORIBOSYLTRANSFERASE ATP-PRTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01634">
        <property type="entry name" value="HisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08029">
        <property type="entry name" value="HisG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="GlnB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01316">
        <property type="entry name" value="ATP_P_PHORIBOSYLTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 16" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP phosphoribosyltransferase catalytic" evidence="14">
        <location>
            <begin position="59"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine biosynthesis HisG C-terminal" evidence="15">
        <location>
            <begin position="220"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1743333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="293" mass="31448" checksum="288B18F54EE3CDA8" modified="2024-05-29" version="1">MSANTVNPDHCLFAVPKKGRLYEKVTAMLKGAGVEYHREPRLDIAICKDLPMTMVFLPASDISKYVGEGNVDIGVTGIDIVEENCSEVERVMDLGFGACRLCVQAPVASQITDVKDLAGKRIVTSFPTLTKKFFDPIDAEKGVTTSIRFVSGSVEAACGLGLADAVVDLVETGTTMKAAGLEVVGTVLQTESILITNPDSKHKKIVELLKHRIEGYITSKKFVMVSYNCSADILDAVSSITPGKRSPTITALTDGGHAVSSLVSKKEIVRVMDDLHAAGARDILVFELSNSRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBV8</accession>
    <name>A0AAD8YBV8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006296</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBV8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="465" mass="53425" checksum="D729386BBFB8FE76" modified="2024-05-29" version="1">MTEHPPRSSTSRSSRRQKPIGLVTVTAFFVFTVYAINLFYMHVHVANLNLHNLDSDVFAPSQRLPPTHSGQSVKDRRFFNDRDVSNSEMNKLKNIRRDEEKDDKIKVESTPAADEKQQHNPLTSSKSHWDSSKSAVLGLATGYPRNVYEGFVGSLRATGFAGHIILAIAKDAPSDVVSYLMEQNVTMKYVEKAEKCTYNGTIGEKGKPIDMQKSGEWKCPKDYPDYKITWARFLYYRDWLNDCPSCTDGVILTDVRDAFFQRDPFVNAMDRNQVHPLMVFEESPETDTEHWLTDRPVSACRKHKLGKKPMLCSGSVMGSREGILDYIESMEEEFKYWMQRENCRIDIRGDDQSIHNYLYYTNRFKNAVSIPHRQGPIHVVGYQAARIFETAKKEAKDAGVGIRRIFNHDNNWKEWLPRLIVNEDGTPSAQVHQVDRFGPLIAKWRNKMIKQGWPYNKEDGIGSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBY5</accession>
    <name>A0AAD8YBY5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pyridoxal phosphate homeostasis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_005228</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBY5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011078">
        <property type="entry name" value="PyrdxlP_homeostasis"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00044">
        <property type="entry name" value="YggS family pyridoxal phosphate-dependent enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146">
        <property type="entry name" value="PROLINE SYNTHETASE CO-TRANSCRIBED BACTERIAL HOMOLOG PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146:SF14">
        <property type="entry name" value="PYRIDOXAL PHOSPHATE HOMEOSTASIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alanine racemase N-terminal" evidence="3">
        <location>
            <begin position="121"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1743631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="265" mass="29129" checksum="72FE4F54B73E91B6" modified="2024-05-29" version="1">MLAVDSYNIREVRGASSCHHRRVGEEGASNYVGIGTYFRGSVRSRLPQHLSIFRPAPSSISAVFTPRHLIPLSTYNNLGRSLTQHNMSTSTVDDVVDIAANIGHVRQMMDDAIASSERESGSVRLVAVSKTKPLELLQAAYETGQRYFGENYAQELMTKSAEMPDDVAWHFIGPLQSNKAAICQRVGLDKLACIETISTIKLAAKLNRAVDSWNEESSGEAKKLGIYIQVNTSGEETKSGVTPGAEVCDLVKQISEECHHFRLMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YC22</accession>
    <name>A0AAD8YC22_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RCC1 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005288</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YC22"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051709">
        <property type="entry name" value="Ub-ligase/GTPase-reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45622:SF44">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION (RCC1) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45622">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="146"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="196"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="414" mass="44009" checksum="80B7929764E504FF" modified="2024-05-29" version="1">MGTSFFYQDVNEIIGSSQPTPPIDTYEPTIDDDEIFPTLNPKRNFEVPFDVGEDVIYASAGSGYTLVILDDESAAVAGFIDNIIDYSGYFGLPQQDLLEGPNELAVIDSVVNLDGDLRAAPDFRRVQAGVKTNDGTMHSAFIDVNGNVYAAGSNNSGQLCIGDLDDRNIPHQIDLGERAVSVAVGGDFTLILGASGDVYGCGSNEFGQLGLGNVLFVDLPDSGNGLRDVRTISAGLDFSLLSTEDGLAVMGSNSEQQLCTDEFDEVTEPFFLDAIGSGDTRQFRAGFQSSYILFRDGSVAACGLNAFGQLGIGAFDDPGPATVTIPGNNFIKTLGVGPSAVSAFFVGLDGVVTVQEETIEVSWELEIQITGTVQIKCYLNSMVTMLPESRQPSTTLLLGDNKETAESTLDQLCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCN4</accession>
    <name>A0AAD8YCN4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005591</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCN4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="397" mass="41882" checksum="EEA7F19002F1FE59" modified="2024-05-29" version="1">MAASSDLLHGSRYKLLYKSKSDKANQSKSAKSSVLGKSKSAGDQSSNEALVHRPYEASKSSKTIMETLLPLDHLPSPYPSMATTVLPSMKPSSSQPVVEDTNSSPTALGTTPTHRPSLHPIISPHVHDIDTETKQPSHYPTIIHNLFTPSDDDEHHVDSSFAPSTTTSYDMMTLSPAPSSTIQPSYSPPPPPSNMPSVASSFVMDPSASPVVEGLFGRPSVQDSSTVTPTLPTEEDTGMDTDGPTLKPSPSFTIITPPTNNEASFSFTVTLSSKTSFIPSSTPTESFTPSIYSSTSTPPSSDAPTASKELNLLNPIAQEQDKFQGAASLMVILACAMAIMGTLFGVFKVMKKDEESVLDEYGAQLAGAAAFDADDIGEVNVEGGGGGVDSHLQLVTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCX5</accession>
    <name>A0AAD8YCX5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCX5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="114" mass="12161" checksum="14AD8AE8577B8762" modified="2024-05-29" version="1">MSSITPDTKKKKIALPSVLSNIRNAVGRAGAEEKAVKNEVEIRPLLPNNRSSGDLVGVGKSSSYAADRSQMRDRSTVPSSGLPPPPLSASSPLFGLGQSSRQTLPREMHHLLCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCY7</accession>
    <name>A0AAD8YCY7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF285 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006372</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCY7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005046">
        <property type="entry name" value="DUF285"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011889">
        <property type="entry name" value="Liste_lipo_26"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02167">
        <property type="entry name" value="Liste_lipo_26"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03382">
        <property type="entry name" value="DUF285"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041972101" evidence="1">
        <location>
            <begin position="29"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="372" mass="41290" checksum="078EBF11EA8A5A41" modified="2024-05-29" version="1">MMQMHSPITSVILVLLILLVASSPQVYAAQCFAANNELKDAAGRYVDNTWSTADEAKYGPIEGWCFTDQVTSMSELFKDASTFNEDITAWDTSSISDMRGMFNGASVFDQDISNWNTSSVTTMSRMFMLASEFNGNIGGWNTSSVSDMSFMFRKATQFNGDISTWITSSVTTMESMFEGASLFNQNLSLWNTSSVTTMKEMFRGASVFDQDITAWTTSSVTDMSFMFFQATQFNQALSTWITSSVTTMESMFQGAAKFDGDISGWNTSSVTTMKEMFRGASVFDQDITAWTTSSVTDMSFMFFQAEQFNQALSTWITSSVTTMESMFQGAAKFDGDISGWNTSSVTTMKEMFRGASVFDQDITTWNTSSVQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD71</accession>
    <name>A0AAD8YD71_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005599</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD71"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF151">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="363" mass="40464" checksum="F4D9EFF18ED56BD2" modified="2024-05-29" version="1">MQTQVMQDCWMRENGGRVNDRFGITEKDGVRGIQAFTDIEEGSELLFCPWHLVIGSSSLQDQMKPGDGMCSVVDEMAKEIRLGVDSLWYPYLDHIGGQRLPADFISEVLLELQGLLTTQDATRHLRWFDQRCDGELDGTAKQSLVAFISRASEVGMIPIYDLFNHHNGKRSAKLTVTEEGVQLLVVGDGGISSGDEIYLSYGLKTASTMYRDYGFVEEWPIAWNFQTAGGNNFAFLEFPDVVAINPSADLLRAVWQSNISLEEYLSLATTHTESLSSADLETFVTAVENEHFPTTFEGDEVTLALLIEQEGGTIANDSSDNISDRISAIRYRMAHKKALASAKLYCNRILTKRMSMGSQDQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YE89</accession>
    <name>A0AAD8YE89_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Multidrug and toxic compound extrusion (MATE) family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_003989</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YE89"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044644">
        <property type="entry name" value="DinF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42893">
        <property type="entry name" value="PROTEIN DETOXIFICATION 44, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42893:SF9">
        <property type="entry name" value="PROTEIN DETOXIFICATION 46, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042038478" evidence="7">
        <location>
            <begin position="28"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="259"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="324"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="443"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="482"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="511"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="535"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1744698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="576" mass="62327" checksum="BD2ED5D63DC7ED9F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEU6</accession>
    <name>A0AAD8YEU6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribosome production factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004512</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEU6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042134">
        <property type="term" value="F:rRNA primary transcript binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000470">
        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10480">
        <property type="entry name" value="Probable brix-domain ribosomal biogenesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044281">
        <property type="entry name" value="IMP4/RPF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22734:SF3">
        <property type="entry name" value="RIBOSOME PRODUCTION FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22734">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Brix" evidence="2">
        <location>
            <begin position="120"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="345" mass="39747" checksum="3DB88978F3FD7B0B" modified="2024-05-29" version="1">MAITKKKGGHASLQGKKPLNTAKVKRTVSNNPGHIKNKLKRSEIYGKYLLEKKARKRQTRIQRDKEAEALGEDAPKKQTPRTLDNTRESEVTTVQPDDEEILADEAEDEFAPYFSDEIRPKILLTTRPMPSGELFHFIADLMRFIPQLYYYPRKTYSVKEICQFGANRKFTHLIVLSEKSKVCNGMLISHIRPSTAANGLGGPTAFFKVSNVIPSTDVPNNGSATSHVPELNLHGFTTRLGHRAGRFLGSLFPHNAQFQGRQVATFHNQRDFIFVRHHRYVFKEGNQVNKETGKKKTKAKLQELGPRFTMKMRWLQEGTFDTQFGEYEWMHKRKEMDTTRRKFHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YF15</accession>
    <name>A0AAD8YF15_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dethiobiotin synthetase</fullName>
            <ecNumber evidence="2">6.3.3.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.3" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YF15"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004141">
        <property type="term" value="F:dethiobiotin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03109">
        <property type="entry name" value="DTBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21343">
        <property type="entry name" value="DETHIOBIOTIN SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21343:SF8">
        <property type="entry name" value="DRTGG DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13500">
        <property type="entry name" value="AAA_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="306" mass="33856" checksum="D68D99651A5F2099" modified="2024-05-29" version="1">MQSSFMLSSAATSTAALCRSFSTGGGQRPIFVAATKQHVGKTTTSLALMAGLQKRFPKVGFIKPVGQQHVTVHSETLGKEIRVDKDICLLKEQFHLDHIDYRHMSPVIIPRGYTKDYIDGKISHEEQLKDIEHAYEKVSEASDVVLMEGTGHCAVGSVVGVNNAQVAGMLGASMILIANGGLGSAFDELELNRVLCEKYNVPIAGVVINKVIPSKYDQTKHYMSKAFQDSWGIPLLGCIPDRPFLGCPALADLERLFKTELVSGQKHRFRHYSVDDMNLITTSLTRFLENIRTNILEHYMLSCDTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YF93</accession>
    <name>A0AAD8YF93_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004669</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YF93"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="101" mass="10994" checksum="EC4D64FEBF8F1665" modified="2024-05-29" version="1">MNLMAPNLSTIAEEFGMDDDERDMKLGGMVALGFFFVGAPDPERGASEAAVMEEVDDDSTLESSIVLQDDNMKTSTCACDVLERGQNPQLEEEHTSQLMSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFF2</accession>
    <name>A0AAD8YFF2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Zinc-binding dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005122</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFF2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052585">
        <property type="entry name" value="Lipid_raft_assoc_Zn_ADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43482">
        <property type="entry name" value="PROTEIN AST1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43482:SF1">
        <property type="entry name" value="PROTEIN AST1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="417" mass="45708" checksum="EC054F7E4FF86950" modified="2024-05-29" version="1">MVTSLPSNSSTLLGGATMKSNFAAQFRLNAFSKQDESRVDEDEESRIDEEEECDRDNVDITVITSSSFINEKTHLLIKVMASNFSVEDAMNMKMKSSGISIHPYVPGELVIGTIEGIGSEVDSIFFDVELGDRVMGMVHGGGCSCFLSAEADNFVKAPTSSGMSNTAALALMHDWVPAYRALSVAKNAMSGASLFGMNILLTDAISAAGQAAIALASEEGANIYCCAEKTHHEYLKSLGSRITCVDLQPNSWLPELKEKMHIVIDNTCMDGYASSWEALGRDGFLICLPSNSLNDDKLFGLFDVGSLKSKINLTKARYLMSQTIIVDTKEDFKAFNVNKDESSAEKRVNFIRDFQYLAFLHEKGTIQPKISEKISLQELCSFFVIYSVAGRSGYNLFKYGMRGTGGTRVCLPWKNEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YG58</accession>
    <name>A0AAD8YG58_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ion transport domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_003582</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YG58"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43336:SF3">
        <property type="entry name" value="GUANYLATE CYCLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43336">
        <property type="entry name" value="OXYGEN SENSOR HISTIDINE KINASE RESPONSE REGULATOR DEVS/DOSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="342"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1745658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="360" mass="40256" checksum="4F194A3D394AEAE7" modified="2024-05-29" version="1">MHPQHGNNPSSCHRHSSSSSFDGGNDEEGPRKPLHDESEEDEIESLNRKQTATETATATAKLNRTKHLANKFLDSNGTITFMSFITVYALYGDDVRIIAFQPNVDIVFLALSAVASAFFLVEISLLCWCKQGYLRRPDLTAIRDVCSIYAWKKRKSTLEWLSKLWNVLQPGSFYFWLDLISTFSMVIEMPWFFQSFGGGGGGGERGGVDSTVDAGAQAANNLKVLRILRMVRLVRLAKLYKYFSTKQSSKTPYSNSSMQGSSDSLDIFPPGSHVGAEMSDRTTKKVIVGILVMLIGIPLLQPDEVAYRNKLAMTTVFENRMLLWMGLTIMKWRIGSLLNHSLLRVLTALILHILGSTMAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YG61</accession>
    <name>A0AAD8YG61_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_003913</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YG61"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06587">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40280">
        <property type="entry name" value="BLR6907 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40280:SF1">
        <property type="entry name" value="VOC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1745989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="367" mass="41501" checksum="6D9269D3BA1B0547" modified="2024-05-29" version="1" fragment="single">SVSVCVYNTQAFSIIHHASRSSRIVDGSVAPFKWQLHAESNPSCEVLLMDHFNINHEKGRHDALRAFYFDFLGCAIDPRKQENIELGNKTLWANIGMHQFHLPEGKPDAQVFDGVITLIHEDLSALMERYNDYLDGDEKFAPLKETEFMVGVLDDSLLMVTDPWGTEFNIMSSDDPEEDRASDVGAQPLIEGHKPSEGLKLEDLTVYVPHDANLEGIGRFYQHVLGAPAIEELGSESSISISMGERQTLTFQYHPDGPDTLVNHHDFSYDEQDEFPSNHGPHISLYVTDLAKAYQSAAKLGVTYVNPRFKRRAYSEGEALDQCMFRLIEIIDPLDENKEVILYLEHEVRSAKTRDGKKYKSCPLNEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGI3</accession>
    <name>A0AAD8YGI3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">N-lysine methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_002698</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGI3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF34">
        <property type="entry name" value="N-LYSINE METHYLTRANSFERASE SETD6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042276018" evidence="2">
        <location>
            <begin position="28"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="3">
        <location>
            <begin position="79"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="419"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1746091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="604" mass="66125" checksum="18B12A90A8C5ABC5" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHZ5</accession>
    <name>A0AAD8YHZ5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Hydroxylamine reductase</fullName>
            <ecNumber evidence="6">1.7.99.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_003566</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.7.99.1" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHZ5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050418">
        <property type="term" value="F:hydroxylamine reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042542">
        <property type="term" value="P:response to hydrogen peroxide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2030:FF:000002">
        <property type="entry name" value="Hydroxylamine reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2030">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00069">
        <property type="entry name" value="Hydroxylam_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004137">
        <property type="entry name" value="HCP/CODH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010048">
        <property type="entry name" value="Hydroxylam_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016099">
        <property type="entry name" value="Prismane-like_a/b-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011254">
        <property type="entry name" value="Prismane-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016100">
        <property type="entry name" value="Prismane_a-bundle"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01703">
        <property type="entry name" value="hybrid_clust"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003658">
        <property type="entry name" value="PRK05290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30109">
        <property type="entry name" value="HYDROXYLAMINE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30109:SF0">
        <property type="entry name" value="HYDROXYLAMINE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03063">
        <property type="entry name" value="Prismane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56821">
        <property type="entry name" value="Prismane protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1745642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="608" mass="66111" checksum="E1CAABE9D363F406" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YI52</accession>
    <name>A0AAD8YI52_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Asparagine-tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.22</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_003444</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.22" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YI52"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004816">
        <property type="term" value="F:asparagine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006421">
        <property type="term" value="P:asparaginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF34">
        <property type="entry name" value="ASPARAGINE--TRNA LIGASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594">
        <property type="entry name" value="ASPARTYL/LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OB" evidence="7">
        <location>
            <begin position="5"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class II (D/K/N)" evidence="6">
        <location>
            <begin position="136"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1745520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="504" mass="57178" checksum="64CC1F78AF92442B" modified="2024-05-29" version="1" fragment="single">KLTSFYGWVRRTRVGGGGSIVFLDLYDGTRVGSLNCLVEEATYLQEGGTDAAEDATQDEQQYKTLTFDQLDQAEHLSLGCAVVVDGKIVLSPPTATQDFEFQVSRVRVIGKVYDPISYPLQKGTEKKMTSLRNLPFYRFRSQASQCVFRIRSKLDMAVHLFMDQEDVQLTDPNIMTVSDCEGAGETFGVSPLMFSNDAEGNPLQVGLTVSSQLPLEATICGFRQVYTCQKSFRAEKSDTAKHLAEFLHVEYEGAFITLDQLIAQSERFVKFVINYALDKCGEDFKWLESKMAPTDMKPTRTLLKECVDRPFVRIKHRDAIDLIRKLVKDKAKIPGDDGKLKRVKVKELPGYEDDLGSEHEKILVQYFGYESVPEDQREAYIKEGKEFGAFVFVTHWPLKIKSFYMAQADDGSGECLSFDLLCPRVGELFGGSMREWRFEKLDEEVKRREMDVSPIQWFLDLRKSGSCPHGGWGMGFDRLCMLVCGVQSVRDVVPFPVYYGHCPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJ55</accession>
    <name>A0AAD8YJ55_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heat shock factor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_001512</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJ55"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000479">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF206">
        <property type="entry name" value="HSF-TYPE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="6">
        <location>
            <begin position="163"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="293"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="45"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="98"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="119"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="293"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="342"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="353"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="371"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="426"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="471"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="491"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="527"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1747549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="586" mass="63783" checksum="3753522F6561C0E1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJE7</accession>
    <name>A0AAD8YJE7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cyclin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002873</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJE7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000093">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0195">Cyclin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="2">
        <location>
            <begin position="91"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="366" mass="41339" checksum="40C8DEE670FA3587" modified="2024-05-29" version="1" fragment="single">SPLRLPFKCACPKTAQHARGHHFSSSNSQHKNKSQSIVMKPSQNLSQDAAAAADSLTVMIEKERTIYKCSGYLDPNEPTIITADDRMTIVDWCYGVVDHCQFSREVVALAMDMVDRYLSIPSYSGDEALRDQNKFQLLSITALYVAIKVNEPVAMSSDLFAEISRGVYTVEEIEDMERTLLNGLSWRCNAPTASQVGHSILSLILPYVKCSEVTWGFLMDELKYLAELAVREYYFSTQRASTIALASIFNAIRQIQGQEHQELLQAFLCIMECFDFDEPEVVVVASNKLHLLLQQENHDHTTEGMMDVPEAEAPKCIETSSLNRRMRQNLKLYLRELELHRGYNPKKSPRIVSRSSPLSVFGCRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJS6</accession>
    <name>A0AAD8YJS6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PS II complex 12 kDa extrinsic protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003272</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJS6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045388">
        <property type="entry name" value="HHL1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20133">
        <property type="entry name" value="HHL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041909810" description="PS II complex 12 kDa extrinsic protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="190" mass="20188" checksum="981FA8D56F32CB1B" modified="2024-05-29" version="1">MKSSMQLSLLAIATALSSTNAFVPAATRSITSVANTELYAKGFGAPAPEPRGKSEGQVERDQKASKYDEIAATGGQEYRIFVRQFGSDDASWLPTGSIAVPRGSQVSDAVFANEEGLRSAIVRAYPKLKGSEMEFEYGYNLKIYPDDPVQVASKSMGSSSGPSVGNWISNLLSPVDASGVAQPVVEEKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YK88</accession>
    <name>A0AAD8YK88_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_002219</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YK88"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="26"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="91"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1746875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="313" mass="34907" checksum="16DE1FC780098158" modified="2024-05-29" version="1">MAAARRFISADTSDTPDNTLEGDLCCASCGIAKVDEVQLSKCPTCDLVQYCSNECQREHKPQHKRACEKRAAELREEILFKQPEGSHLGDCPICLLPLPLGCRKSRIMSCCYKKVCNGCAYANDIRELKESLEHTCPFCRRSFPRSEAAANMNVMKRVKVNDPAAIRGKGIQCYEQGDYVSAFAYLTRAADAVDDADAHDQLGSMYRKGKGVEKDTNKAVYHWEQAAIRGHPISRYNLAVLDMSNGRFKRATKHWLITACIGHDPSLERLKFGYMRGYVEKDDFATALRGHQSALDAAKSPQREAADAAKLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKA6</accession>
    <name>A0AAD8YKA6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Glutathione reductase</fullName>
            <ecNumber evidence="11">1.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_001655</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the reduction of glutathione disulfide (GSSG) to reduced glutathione (GSH). Constitutes the major mechanism to maintain a high GSH:GSSG ratio in the cytosol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>2 glutathione + NADP(+) = glutathione disulfide + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11740"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58297"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="8">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.7" evidence="11"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKA6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.30:FF:000003">
        <property type="entry name" value="Glutathione reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006322">
        <property type="entry name" value="Glutathione_Rdtase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046952">
        <property type="entry name" value="GSHR/TRXR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01421">
        <property type="entry name" value="gluta_reduc_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004776">
        <property type="entry name" value="PRK06116.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737">
        <property type="entry name" value="GLUTATHIONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737:SF2">
        <property type="entry name" value="GLUTATHIONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="FAD/NAD-linked reductases, dimerisation (C-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 8 10" id="KW-0274">FAD</keyword>
    <keyword evidence="2 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 10 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 10" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="14">
        <location>
            <begin position="6"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridine nucleotide-disulphide oxidoreductase dimerisation" evidence="13">
        <location>
            <begin position="357"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="475"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="461"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="183"/>
            <end position="190"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="9">
        <location>
            <begin position="44"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1747692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="499" mass="53900" checksum="FC151DD170C3CC24" modified="2024-05-29" version="1">MTTYDFDLICIGGGSGGIACAKRSATSFGKKVLCIERARLGGTCVNVGCVPKKVMWSAAHIAHTLKHDMEHYGFSTGGEVTLDFPKLKQARDKYVKRLNGIYASGFAKAGVEHVFGEATFVDEHTVKVTDKDGQVTNYQAEKILIATGGRPHFPPGEGVEENCISSDGFFDLEDLPKVAVVVGAGYIAVELAGVLNSLGSETHLVVRKGRALREFDPLISEALDREMKHLWRGKGRTDGGNKKNITLHNGDTIYNADVVLMAAGRVPNTEDLCTDCEWAPNTETLHLEKCGVKITPRKYVVVDEYQNTNVENIYALGDVCGVVELTPMAIAAGRRLADRLFSSNPIHTTSKVSYEYVPTVVFSHPTIGTCGLTEPKAIEKYGQENVKVYTSRFSDSHYGIFDMKPEDKPKTVMKLVCAGLDEKVVGIHVLGMGSDEMMQGFGVAMKMGATKADLDSCVAIHPTASEELVTMGTWGTSPQESGAKVSPLNGAAAAEPRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKU9</accession>
    <name>A0AAD8YKU9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKU9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="338" mass="37383" checksum="2368E12AAA72815E" modified="2024-05-29" version="1">MSFNHPKGKNPPSSREAEVLERQRLMATRLKNTNKAKPPPPPSKATCSICKRSNFKTAKEAAEHEKQCRTKKLSSVKTKGAGTTTSPILIGGEITAEMALEHARRRAAARRNTQQPTSVMKNDNEKKPQQSPLVAAKRSDLRTTKMASSSQSEQSSAVAAAGSLSSLLMSNADTAKYMKPNAPKLLQHYNKIEPNDYWKNIRDWDFLGELNDKMGNNSSGKRINRDGNSDGHATTKPLPDTFDSYRQYCALGTTLPRGGTCTIIIRGDIRHSLWRSKPEKSPIKVFLQPLKKDLDGSSENMGVQVKNVLTDNYKDRSFIANDIVLLLKKESLCGSIQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKV9</accession>
    <name>A0AAD8YKV9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002564</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKV9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042145003" evidence="2">
        <location>
            <begin position="25"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="175" mass="18486" checksum="34C76E3243D36A70" modified="2024-05-29" version="1">MKLSTAAIMTISASVLSLPATVTASSSKTSKQAKGGSYSMSVHPTSKASKKANVNGGSYSMSVDTDTNSCRRKLRFNCAPFKEGLKSCDELTNSCANGPFRFDCKPGPNKSGEEVCGRMCNPGCPQFPPPVGTNPCTYAPDLECYPSNNGRPQCCADDPTGSQCSKNEPCENEMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLA1</accession>
    <name>A0AAD8YLA1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_001393</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLA1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="159" mass="17770" checksum="6A1CE1CDB45AEB2C" modified="2024-05-29" version="1">MASQTNDIEHAMEKLLRCSDDTDDRRLPEVYLSQNNRCKSFGSISDLLNPEEEVKSDVDLYTHATSDLQTLNDMFAKFRPVANKKHIPDQDDAALFAYMEKRSSVSHGPMGRRDSNKSSRSSMSLSSFVDGFDEVEENSRCGSLSSLLGSLGLNLAQIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLF2</accession>
    <name>A0AAD8YLF2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_000685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLF2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005331">
        <property type="entry name" value="Sulfotransferase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03567">
        <property type="entry name" value="Sulfotransfer_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1748746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="255" mass="29752" checksum="2B0DA265E56E30D7" modified="2024-05-29" version="1">MDNMCSLAIVRNPYSRMVSIYGYNRFGEGESFPTFLRRWKRLMRHYMEKGEKEEWYTPCHLLPMFEYTHHDGKQIVQSVVKQEELKLLKTRDGATEAMKQDNTISDLPDLVRDALVGMPHTNSRKTGQKWWDFYDQETMELTLEMYAMDFEVFGYERTIKQRPDLIPPKKDRGVIMEMSKFDGFSRNSLRDSSGARVSQRGLFSSVRSSVRSNAESARSTLKQSVMEGNKDELLGALVGFRYFSEVTEVDEDKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMA1</accession>
    <name>A0AAD8YMA1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Malonyl CoA-ACP transacylase</fullName>
            <ecNumber evidence="2">2.3.1.39</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000547</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.39" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMA1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004314">
        <property type="term" value="F:[acyl-carrier-protein] S-malonyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052760">
        <property type="entry name" value="Mitochondrial_malonyltrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47170">
        <property type="entry name" value="MALONYL-COA ACP TRANSACYLASE, ACP-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47170:SF2">
        <property type="entry name" value="MALONYL-COA:ACP TRANSACYLASE (MAT) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Malonyl-CoA:ACP transacylase (MAT)" evidence="1">
        <location>
            <begin position="1"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="187" mass="19597" checksum="555553B757AC4260" modified="2024-05-29" version="1">MAAVEKLKAEKGQEAVDEATCAMGLSLGEYSALCFAGAISFADGVKVTKARGEAMQAASDAIDTGMVSVIGLSKEKVGELCEAASEKSGEKIQIANLLCNGNYAVSGHMKACDTLAEIAKPEFKARMTVKLAVAGAFHTDFMAPAVESLEKVLEILKSISHVSLLFPTLMPAPTLILILSKSFLPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YNE6</accession>
    <name>A0AAD8YNE6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001206</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YNE6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="204"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="486"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="585"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="816"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="336"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="454"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="491"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="505"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="618"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="674"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="712"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="728"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="770"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="816"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="855"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="872"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="902"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="929"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="942"/>
            <end position="952"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1749267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="952" mass="99584" checksum="A1C2E47CC3127DB8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D449</accession>
    <name>A0AAD9D449_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin thioesterase OTU</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_017065</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000078">
        <property type="protein sequence ID" value="KAK1732240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D449"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22744">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13312">
        <property type="entry name" value="HIV-INDUCED PROTEIN-7-LIKE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13312:SF0">
        <property type="entry name" value="UBIQUITIN THIOESTERASE OTU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02338">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042257089" description="Ubiquitin thioesterase OTU" evidence="5">
        <location>
            <begin position="35"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="OTU" evidence="6">
        <location>
            <begin position="111"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="37"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="45"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1732240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="458" mass="51297" checksum="D188BD606258261D" modified="2024-05-29" version="1">MEQTLQPWRCRAATGAAALLALLISWSIIAPAASSIPRSTASTSNNIASPFESSSSDVNNIRRPPWNPSKHINNHGYLKQLFRRIPAEIIGETTSDNNNCNDDDRSLTTPVVIRQVPGDGDCLFHSLAIALSFTEDGHLMRLDTQQGLQQLKQSSRKLRRMAVECLSSSCSTKKQRSTTKRYKRLFIQGSDSMKTSQLLSTASSQYGISPEEYCELMMQDSYWGGGPEIVALCAVLRRPIHVYELVALKDGDGDCVGESDDVCDTSDNNEGQIQQQQQQQQPYLTMYKDQTSNQFCLRLLATFGSPKFDSKEPLHILSADSRFPDVDPRCALRDGNHFLAMFPVDRMRACLRDCYVNGGSIERTMSERNQRVRGGGSTAVGTDDGVEMEVDGISDDAAAGLSWLFHGEWYDDLPCDIPVRCDLDNEEEGGKRSWFDLRKRRKLQNKRRMNWLCIAPSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D474</accession>
    <name>A0AAD9D474_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Leucine-rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015905</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000050">
        <property type="protein sequence ID" value="KAK1733346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D474"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="196" mass="21842" checksum="9B64F1440DA89D2F" modified="2024-05-29" version="1">MAADGWHTYYGRDGEIIPPGVTRVRIDESLTVIPAAAFRANRKIEEVKCHDRVKTVGGSAFVNCPSLRRVIMPGVEVIEQYAFCDCKALMYVECDKLERIGRGAFAWCESLTSINLPSAKIVKLRAFASCKALTNINFGKELESIEDGAFAQHQSFLNEAATTLQHTLPQDIMVNNVLPFLELPSYTFEVGDHEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4B4</accession>
    <name>A0AAD9D4B4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_016099</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000052">
        <property type="protein sequence ID" value="KAK1733242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4B4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="98" mass="10560" checksum="B66C05B6786797F2" modified="2024-05-29" version="1">MEQRLSYAAAMDAQIKLLEEECALDTGQSRNDAVAKGVQILLRKLECALSMGQSSNDAVAKDAQIKSSKGECAAGMEQRSNDATLNNAQIKLRKVDCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D737</accession>
    <name>A0AAD9D737_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013944</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D737"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049492">
        <property type="entry name" value="BD-FAE-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20434">
        <property type="entry name" value="BD-FAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BD-FAE-like" evidence="2">
        <location>
            <begin position="9"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="350" mass="38004" checksum="B0FE175F3C80E266" modified="2024-05-29" version="1">MNLVGDTVESAGQQYLDAGYTVAVLYYRLPRSETTTSWLVCSDPYEVLDDVSSAMTHLLENAADYNVDADQIVLSGFSAGGHLASLYSSLCNARSSACPAGQVLHFPFMEKGSKIFCSEVGTAFNALQDYDECFPTVLVDNATPPTILYHASSDPIVPTSEMTDFVYALGQQGTSYEYYEVLEGGGHYLVPFSQVAAVSDGVLDPSGDYASLIERALMLPNPSCVRCDDIVTPWMKDNGKTCDVTTWLITNKCVEDEQWVTNGYCRSSCYDAGRGYVNEVCCPPPTPPSSCTECSDDATPWMENNAKTCATSPSSIETNCNENGWWVSNAYCQLSCFAAGRGYEGIDCCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7G5</accession>
    <name>A0AAD9D7G5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="4">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_013852</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="4">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7G5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042294798" description="ATP-dependent RNA helicase" evidence="6">
        <location>
            <begin position="28"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="DEAD/DEAH-box helicase" evidence="7">
        <location>
            <begin position="222"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="47"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1735689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="371" mass="40761" checksum="F91EFD6F78ACD144" modified="2024-05-29" version="1">MMTTATLVLFLLTTTAILLIFQNGGSSSSNNNNILFVNSWSIQPPSFASRTKKPTTTLLQTTNDGSSNSSNEQPLDLATQVTSMGLNELQTQFRLAIAREDMDAAILYRDELAERVDSSNSYNYNDDTTMTDEERLKRKRQRLSWAGLGTAPWLMERLDALEYALPTTIQINAMEAVNAILSDSNDYNNSVKNIINSSNDNRDEDDDDNTLEERLIQSTSTIQNMGLLISGSTGSGKTLAYLVPTLSTLSQTLFTRQRIRIKAEEDVGDLMGDLLERVAVQTSPSMKGQGYDQVGINKQSSSSTLGKSGTGVKSPIALIVVPTRELGVQIALLLFELVGGEQKAICHRAQWQTKHVQVQRTQGCQDCMCVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D953</accession>
    <name>A0AAD9D953_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D953"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="192"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="532" mass="61279" checksum="A21ECF055E13D352" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DA01</accession>
    <name>A0AAD9DA01_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011429</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DA01"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="238" mass="25597" checksum="CB7BEDB339B5D88D" modified="2024-05-29" version="1">MAITSSDIGNSLLLRFWLRNILQSLVQNSVVGAAAAFGDAAQQSMEAERRRMQNGTPLLPGSAAELPNLSSQDQQQQQGLTSALLSATSFELTNAGFMDGKVVFDAKAILPRDENGVSNSLQFRIRAKLAPTAISETVSQTIQQQDAQEVYNALGFLQPECRLATNPLYAPIGGNLLRNLLPNLIPEYLWLPFGVGVAVPLGRGCEIYRAEIDACKEGGFLCKIDGSVNVVNSSSNIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAV9</accession>
    <name>A0AAD9DAV9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Sphingomyelin synthase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_010411</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sphingomyelin synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAV9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047493">
        <property type="term" value="F:ceramide cholinephosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033188">
        <property type="term" value="F:sphingomyelin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045221">
        <property type="entry name" value="Sphingomyelin_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025749">
        <property type="entry name" value="Sphingomyelin_synth-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21290:SF25">
        <property type="entry name" value="SPHINGOMYELIN SYNTHASE-RELATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21290">
        <property type="entry name" value="SPHINGOMYELIN SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14360">
        <property type="entry name" value="PAP2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="477"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="Sphingomyelin synthase-like" evidence="11">
        <location>
            <begin position="382"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="172"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="172"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="183"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1739095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="550" mass="60193" checksum="A08B280B5843E9A0" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DB14</accession>
    <name>A0AAD9DB14_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-L-isoaspartate(D-aspartate) O-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.77</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_009907</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.77" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DB14"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004719">
        <property type="term" value="F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000682">
        <property type="entry name" value="PCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579">
        <property type="entry name" value="PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579:SF0">
        <property type="entry name" value="PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01135">
        <property type="entry name" value="PCMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="6 9" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042026602" description="protein-L-isoaspartate(D-aspartate) O-methyltransferase" evidence="8">
        <location>
            <begin position="30"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1739364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="303" mass="33305" checksum="DE6A8BF8D6A3C53C" modified="2024-05-29" version="1">MMQCHHLQRNKVLLLFILFSAALPSITSAYANNNNNEAKPKPLMRAWMCSGKTQRDMVDKLAQAGIVKSAINKEALLRVDRKNYVLRTQQGDSAHQDSPLPIGFGQTISAPHMHAQVLEDLLPPLLAASKDRPDKLLKILDVGCGSGYLTAVFGRMVESKENRRKSTPLNEGKVFGIDVVPELVHMSKTNVMKEDGDLLDSGTVEFMLRDGWKGYPENAPYNAIHVGAAAATFPKQLMMQLAPGGVMVVPVGPDGGIQYLYRVERVGDGGAVVGVDESKGFQEDDYELYRVLGVRYVPLVQKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBE5</accession>
    <name>A0AAD9DBE5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DOMON domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007804</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBE5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09631">
        <property type="entry name" value="DOMON_DOH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045266">
        <property type="entry name" value="DOH_DOMON"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="SMART" id="SM00664">
        <property type="entry name" value="DoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50836">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DOMON" evidence="2">
        <location>
            <begin position="118"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="476" mass="53398" checksum="20431E871529957E" modified="2024-05-29" version="1">MMMRSPWAALSRGGMAVKATFVAVVLIAAAASSFMENKVESSTNESSMQSLAERFVNDASTPTQKDQEMTTPAQLRRLQENKRKDRKKATYDDGQSMVTNAAAAKDCTSQFCQKQLSDACLVEYKVNNGIPTTITMVLVCEGSRWVGIGFSESGKMMNSDAVLGIPGTAPEKYRLGGYDQSAVVAMERQRQTLIDASVNYYDADDVTVLKFTKIMKEDGEVEIKPGKNTFLYAKGIFEDLNYHQERDLFELNIPKVDTAAEVAPAAEESSEKKRKDRDKVKKDDDSAEDPSAENQPKESKRKQGRGDGKQTLAEQFASLGPIQLRPLKDLRPNLSPPVPVDDEFPYPYPKIRFTEWASLSHQTREIMKENFGYNKGNWNALGLNDNERMTCSQLTDAQRQAIQLLGWNCDVWDCFINHYKSYNAEQLGDKKLLGHVDVVRSAWVKLWADLSEDELQSATRLCFTEFVWDVGYLGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBR4</accession>
    <name>A0AAD9DBR4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007970</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBR4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="315"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="377"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="579"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="501"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="388"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="591"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="609"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="635"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="647"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="694" mass="75899" checksum="DC451E5B122CB77F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBX2</accession>
    <name>A0AAD9DBX2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">16S rRNA (uracil(1498)-N(3))-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.193</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_007424</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>uridine(1498) in 16S rRNA + S-adenosyl-L-methionine = N(3)-methyluridine(1498) in 16S rRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:42920"/>
            <dbReference type="Rhea" id="RHEA-COMP:10283"/>
            <dbReference type="Rhea" id="RHEA-COMP:10284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74502"/>
            <dbReference type="EC" id="2.1.1.193"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNA methyltransferase RsmE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.193" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBX2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070042">
        <property type="term" value="F:rRNA (uridine-N3-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18084">
        <property type="entry name" value="RsmE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006700">
        <property type="entry name" value="RsmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046886">
        <property type="entry name" value="RsmE_MTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00046">
        <property type="entry name" value="RsmE family RNA methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30027:SF3">
        <property type="entry name" value="16S RRNA (URACIL(1498)-N(3))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30027">
        <property type="entry name" value="RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04452">
        <property type="entry name" value="Methyltrans_RNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 14" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="7 14" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042072771" description="16S rRNA (uracil(1498)-N(3))-methyltransferase" evidence="12">
        <location>
            <begin position="22"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA small subunit methyltransferase E methyltransferase" evidence="13">
        <location>
            <begin position="176"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1741851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="364" mass="40402" checksum="E6A99DBB057502D0" modified="2024-05-29" version="1">MMSTTLRCIITMLLQASITVATRIQPLSFCHIRQLGRFHRASSLHLNRILFDTSEIDKSDTSVSGRQESGVDEAPMATVTLPKDDYRTIHIAKILGLHNGDSLRAGTVINPSDEEDEFAGLLTDDATITWLPEGKIKKAEPTKNGDPPGSLCISIPQPPKTYLSTQSSDEGMDDTPKVSLLLALPRPLQLSRILPMVSQLGVDQLILTNAMKVPKDYFGSHIFRKPEVLRGLLVEGLAQSGDVRLPNVHVTKRLKVFVEDELDELFPLDEVVRVIAHPQRRDIDGREFGPAPLRMTDIEFPKSDKPRRLLVAVGPEGGWTEPYELDMFRDKGFQQITLGTRVLRSDVAVVSLLSLAHEVCSKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DC44</accession>
    <name>A0AAD9DC44_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DC44"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="316" mass="34581" checksum="244CAF965921C9BD" modified="2024-05-29" version="1">MEEVLQNPKATWEEIRLAMKSHGHATNGGAMTTLLFPVTTKEGTSKETGQKGRVVETAAKPGAEGDDNAGSLHHGQLDELLSNNTPMNSDFGYKPCRSRKPATIAPKAGRVGSANSINRAVVTSSSTSITTDLDNASLASVDMMDFGVDNDVVAYSMDRLNEIDERRRESKCSVTTDDSTYSTDGFLDWNHDDGSSACPSHAESSPGKQEQDDTHNNDHERAARFDDPPAPEVRHKIWHFEEHDFEPEIQQPVIPKMFKRLSSGTMNTVSSLISNLALELEPGPCTPPKEATTDEVKKALSRSISFYRVDGRRASC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDL7</accession>
    <name>A0AAD9DDL7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDL7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42256:SF1">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42256">
        <property type="entry name" value="OXOGLUTARATE/IRON-DEPENDENT DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="418"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="453" mass="52166" checksum="BD90E69F165ED1F6" modified="2024-05-29" version="1">MDGPLSSDRYHRRGGGAGSSRSRSRSRGRDNHHHHHRHRGGRHWKDNNYNDHRRNNNRGSYDDDDRFSRERSRDRYEHDDNSNNMSRRDERYDNRGGGYHNDDYHQRGGVQYNNNNNHHHHGPPAAHNDHRNNNHHHHQNPPAAPAAHNMPPHNIKAAAPTDPNLDQLNDDPRGNDPTKRITKTAKRNGNGRNTESFDPASTLLRPDLRIWVGSNKDTTYTKPLKHDDVVIIPELFGPESNWDIYYKLVSELRTLQANNVKNSEWQSWHEGAHLISKNPVGSPTFEMVIEKLCEYFCIRRKSVGTRFNWYRDSSDWKPFHHDSAAYNPKRAKDQNITVGVSFGARRELAFLHATPQQNGEKCKIYFPQTNNGVFSFGRDVNIQWKHGINALPEEEQDGKGRISIVLWGLAENVIEEEGSPPLLGADGQGAHAQRDGHRGNHRRGNNNHHRGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDX9</accession>
    <name>A0AAD9DDX9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005653</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDX9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="345" mass="37637" checksum="63637ED759F1D26C" modified="2024-05-29" version="1">MVNADDKAVYPYTGFFAITPPPPSDPSIIEADGGKWIRLPSDGRLVEYFVHGSTKNDAAILVDCPGGGATGALVGKLPGVAEWCEAHNVKIISPSYPGFGHSEVRPGWTIGEWPKSDLEPILEQEGVTDSFMVTGTSFGTPHAQAMAVYFGERVKVLGLRVPYVGRHVSEDVGLPLGQANMRYDSKSCNTNLIGHVIGKAFMSTVSDPASFFDEPSGASRALISCLQPKALEQIKKLNNEHEDAMQCLKYDVNRGVVVSGQGWLYMCATDTLLDHKFDVRDINRDKTNIPVIVWYAEDDEDCPPSHGAWLVEEFEGKSRSFSGFGHVGAAFVDHVKFLDEVRMVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEM5</accession>
    <name>A0AAD9DEM5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">dolichyl-phosphate beta-glucosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.117</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_005975</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a di-trans,poly-cis-dolichyl phosphate + UDP-alpha-D-glucose = a di-trans,poly-cis-dolichyl beta-D-glucosyl phosphate + UDP</text>
            <dbReference type="Rhea" id="RHEA:15401"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19502"/>
            <dbReference type="ChEBI" id="CHEBI:57525"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.117"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:15402"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.117" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEM5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004581">
        <property type="term" value="F:dolichyl-phosphate beta-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04188">
        <property type="entry name" value="DPG_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035518">
        <property type="entry name" value="DPG_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10859:SF91">
        <property type="entry name" value="DOLICHYL-PHOSPHATE BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10859">
        <property type="entry name" value="GLYCOSYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="14">
        <location>
            <begin position="63"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00045097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1743354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="345" mass="38198" checksum="8AAF4B56373E4657" modified="2024-05-29" version="1">MMALAETVAGAPELYYSIIGIISILTICYIFYPAYKCKKGGLGCTETILAGDKSNGGDNDLLSLIIPAYNEEERLPIMLDETLVYLNKDRESLTHLFDAAVGNSHQRRNKSLIKYEIIVVDDGSSDNTCNVVRKYAATLNSGDTVKLISMHQNVGKGGAVKSGMLASKGQLCLMVDADGATDIADGLPKLLKEMHTLNNKERHDTSLPPKSVVFGSRAHLENESSASRSKVRTFLMHAFHFFVKALCSPRIKDTQCGFKLFTRSAAISLFTNLHLRRWAFDTELVVIAERLQVSVSEVGVIWHEIDGSKLDGGKLSLALVSLGMLRDMLCVRACYFFRIWKMYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFI8</accession>
    <name>A0AAD9DFI8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFI8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="209" mass="23310" checksum="9A9B48DDE89A1CD7" modified="2024-05-29" version="1">MNTTASSSHKRSHIELEYAHPSSSTNTTIMTSSKPRLIHESLNNISQSIRFLVTGFLSQIIFMTTYNLLISIFEPMGYPASTIYAIFYTIYIPVGHALTALCVFGWPEKYLPSLMANAPIGLTAMAIGTALTGFLSKIGFNAMADDWISSIIGTDKPVEEEEESLFIFGGHGCDWGLVFCLEFVCQFRKEDRCEREGIVRRLRVFGGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFQ7</accession>
    <name>A0AAD9DFQ7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002658</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFQ7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="entry name" value="Intergrase catalytic core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="581"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="733"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="751"/>
            <end position="760"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="779" mass="88457" checksum="93F6B17AB1F57643" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG67</accession>
    <name>A0AAD9DG67_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Chitinase</fullName>
            <ecNumber evidence="12">3.2.1.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_003901</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="12"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00104">
        <property type="entry name" value="KAZAL_FS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002350">
        <property type="entry name" value="Kazal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036058">
        <property type="entry name" value="Kazal_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF333">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00050">
        <property type="entry name" value="Kazal_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07648">
        <property type="entry name" value="Kazal_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00280">
        <property type="entry name" value="KAZAL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100895">
        <property type="entry name" value="Kazal-type serine protease inhibitors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51465">
        <property type="entry name" value="KAZAL_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 6 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 6 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042010299" evidence="8">
        <location>
            <begin position="18"/>
            <end position="2253"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="10">
        <location>
            <begin position="408"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="10">
        <location>
            <begin position="763"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="11">
        <location>
            <begin position="1116"/>
            <end position="1450"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="11">
        <location>
            <begin position="1558"/>
            <end position="1908"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="9">
        <location>
            <begin position="1983"/>
            <end position="2039"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="9">
        <location>
            <begin position="2100"/>
            <end position="2157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="357"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="523"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="814"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1906"/>
            <end position="1929"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1941"/>
            <end position="1984"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2050"/>
            <end position="2096"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2169"/>
            <end position="2200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="379"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="814"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="892"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1906"/>
            <end position="1915"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1916"/>
            <end position="1929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1941"/>
            <end position="1975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="2050"/>
            <end position="2081"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="2085"/>
            <end position="2096"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="2169"/>
            <end position="2197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1745977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2253" mass="243448" checksum="958F510AC21D9CAD" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGN2</accession>
    <name>A0AAD9DGN2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-dependent protease ATPase subunit HslU</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004234</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGN2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009376">
        <property type="term" value="C:HslUV protease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050052">
        <property type="entry name" value="ATP-dep_Clp_protease_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102:SF3">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE ATPASE SUBUNIT HSLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase AAA-type core" evidence="1">
        <location>
            <begin position="23"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="312" mass="34679" checksum="8B76401FD682C127" modified="2024-05-29" version="1">MRNRWRRRQLPQELLKEVTPRNVLMIGPTGCGKTEVARRMAKLSDAPFLKVEATKFTEVGYHGRDVDQIVRDLMDVSMSLTKKRQMEKLRGEAKLLVEDRILDMLSGPEYSGTKGQRESFRSMLQEGLLENQELEVDVPENLGGAAGKDGDGTVLAFGGDSNSMNVQAMTDLMKKLGGAGGRGGRGGPPTERKKMPISEAREVILEIELEKLLEKVDLKKEAVTAARRLVLCLLMKLTKFALVGISIPSRLTQVPKGYREICFLLLREQRSAPSMVMSTQITCSSLEVVPSMQSNQAICCQSYREGCLFVLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGS3</accession>
    <name>A0AAD9DGS3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sel1-like repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGS3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="154" mass="17068" checksum="A1A49B0B0EBA3804" modified="2024-05-29" version="1">MGMSRLDEGNYKSASEYLSKAAELGDATAHYNISVLYREGEGVEKDEKKELRHLEEAAIIGHPFARHILGVTEQRKGRRNRAVKHWMIAAKLGEDDSLENVKMAYRCGLVSKDDLASALRAYQAAIDATKSPQRDEVEAACKGLGLDSRFLSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGY6</accession>
    <name>A0AAD9DGY6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004534</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGY6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1745243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="277" mass="31060" checksum="151E465ACF6B00B1" modified="2024-05-29" version="1">MSHGTYQVTEWNKQQTMNNKIDRLLLGEADNVVLGGVSRIIHKLCFVLEHTSIICTRVTEENWVYRRIIQQYNNNDDNDNESKASSTKNKEGPAIPAWFQAIAPYAVLCSLGRPTKSKWLEPRSGVFGRVVILVLVVPFDQFGDTISNGRKVSPVGWEIDPKSFWLEEHGIWMEAPRYNLQPGRYLVTGGRLRTSVLTIHPADENGVKNWSLDGGVLYDVTHLPCRSALYVDEGNGGSPLNARREDFPVTPGAEMPQVEGCKKQDYAVLFVTGVEDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHG2</accession>
    <name>A0AAD9DHG2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001919</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHG2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007511">
        <property type="entry name" value="DUF501"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37163">
        <property type="entry name" value="CONSERVED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37163:SF1">
        <property type="entry name" value="DUF501 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04417">
        <property type="entry name" value="DUF501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="298" mass="32791" checksum="700BC4319DA12498" modified="2024-05-29" version="1">MATLMGAVTSMHHATAAFTSGLRKELRPTKRNIFPGAIPITEADKETCARQTGQVAPGNALMGKPSQCSCKHGYPQAFSLDPAPPTQQFKRRSMDRVNSGLLKLTCPLIVNAVDALEDEGFINKMNSILAAKEGEDELSQCMNDAHAIHSSTRKKLIFGPARDDDNQTFQMLKSKLGDKGAEYFLDSGVAGANPLTKKKDVKCLHAWLADYLFRITDEEACCDGMTSNHPIGEAILQSLKERDIDFTGTDTCYHVCSGGGVDVESGDGAVTVPIARNKQRKKKDKEFERRRRRQDRNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHJ3</accession>
    <name>A0AAD9DHJ3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_003737</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHJ3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1745813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="327" mass="36339" checksum="16F4042D80603B31" modified="2024-05-29" version="1">MYCCLEVDLIIMKLYTALIIASIAPVSGAFDVAAAIPAFVETSTEQIVCDEQVRSTQPYYCFGSEYQNCDCWQEICGLCLPQCCFKNKGNCPRNMDNAQCNTSPEPMPSPPTPPPNNRRPGSNYCTYSPPDYACYPNTSGKPGCCWDDDGEYCPPQKPGCHQQQQPVVGSDYCTYGFDYECYPGTGKPACCLQDGGRNCPNQQPPCQQQQRLGSNYCTFGFDYSCIPSLANLNAAFRMVVNFALLNVKRVHPRQCRQTNNPLLKVKERPTLLHFARLRQVLLDKTYAHGLQTMHVFLTLMGGPHAARAPKAVTLGQARNVNHAARRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHZ7</accession>
    <name>A0AAD9DHZ7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Homeobox domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_003067</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHZ7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008422">
        <property type="entry name" value="KN_HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050224">
        <property type="entry name" value="TALE_homeobox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11850">
        <property type="entry name" value="HOMEOBOX PROTEIN TRANSCRIPTION FACTORS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05920">
        <property type="entry name" value="Homeobox_KN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 4 7" id="KW-0371">Homeobox</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="6">
        <location>
            <begin position="129"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="4">
        <location>
            <begin position="131"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="197"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="216"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="243"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1746460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="466" mass="50881" checksum="571C29A1267F16B7" modified="2024-05-29" version="1">MANDNTDQQGVKPSAGERVDLATPALSICSSSRSASPTSHISSNVAMAAAMNKKNRQKNDKAVEVLNKNSVVIARFRTQTECAKYLQATPEAVSYHCSKKGGGICNGLVIRPCDNSDDIEFGLFDGAEEVRPKRRPQLKPETVDILKRWILSPDHKNNPYPTVKETATLMRKTGLDKTQLKHWFNNARKRILKPMLKKEKAASLQAEPPAPSPVVQEKRKAAPERKMKRPAKKTRVESDVENSDSSGTAGPSEAQVSQFGIMFGSERAGAGTLNAMHQEDSMAMGMTGTLNAMHQEDSMAMGMTGNINPMSLGFNQAGPSAAAATAMMGMSGIPFDNSSDFLRNQSYQGISFGNNSFPPQQQQHQHQQIQPSPVVFKQQVASMAMKEATIAFKNMEDAYAMAKEIMSILSASGSTTNIEEDPRVIEATAHAKKLHSVAMFKLKVSKRASEEAEKAFETMQGFHRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJL2</accession>
    <name>A0AAD9DJL2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleotide-diphospho-sugar transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000049</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJL2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005069">
        <property type="entry name" value="Nucl-diP-sugar_transferase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03407">
        <property type="entry name" value="Nucleotid_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleotide-diphospho-sugar transferase" evidence="1">
        <location>
            <begin position="106"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="553" mass="62153" checksum="C040C58D59A72AC6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DK11</accession>
    <name>A0AAD9DK11_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HSF-type DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_000978</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DK11"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF206">
        <property type="entry name" value="HSF-TYPE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="6">
        <location>
            <begin position="24"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="117"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1749039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="252" mass="28420" checksum="20D7395B8C652CC2" modified="2024-05-29" version="1">MNLSPLNVDNYPISDTMEQQGTPAQLIFFRLLHKMIANETHSGCIVWLPDGQGFGIPSKQAFTDEILPNYFGQSKFSSFTRRLKRWGFVRKGGFFRHSEFKRDMVFDEDDFDIQSHHPTPIVNANIPSRSKGPLKKRFKQRLPSPPPICLSPSSGIGGSGKSSSDIHIMPELLRVINKKKRKERNDLPLLPSEVAEASKSTEEIMVARALASLELKVRQQSSPLVRYEECTQSSVPIPYLIKPKRLSLSKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-12-02" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6V1AQF5</accession>
    <name>A0A6V1AQF5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">CCR4-NOT transcription complex subunit 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">QTG54_006604</name>
        <name evidence="15" type="ORF">SMAR0320_LOCUS15771</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the CNOT2/3/5 family.</text>
    </comment>
    <dbReference type="EMBL" id="HBGZ01021928">
        <property type="protein sequence ID" value="CAD9616587.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1743007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6V1AQF5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1020">
        <property type="entry name" value="CCR4-NOT complex subunit 2/3/5, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038635">
        <property type="entry name" value="CCR4-NOT_su2/3/5_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012270">
        <property type="entry name" value="CCR4-NOT_su3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040168">
        <property type="entry name" value="Not2/3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007282">
        <property type="entry name" value="NOT2/3/5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007207">
        <property type="entry name" value="Not_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23326">
        <property type="entry name" value="CCR4 NOT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04153">
        <property type="entry name" value="NOT2_3_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04065">
        <property type="entry name" value="Not3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005290">
        <property type="entry name" value="NOT_su_3_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0678">Repressor</keyword>
    <keyword evidence="8 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 10" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="CCR4-Not complex component Not N-terminal" evidence="13">
        <location>
            <begin position="3"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="NOT2/NOT3/NOT5 C-terminal" evidence="14">
        <location>
            <begin position="493"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="244"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="305"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="317"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="341"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CAD9616587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1743007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="625" mass="70650" checksum="DCD282B0440AAAC8" modified="2020-12-02" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2KAW4</accession>
    <name>A0A7S2KAW4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ribosomal protein L27</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_011969</name>
        <name evidence="7" type="ORF">SMAR0320_LOCUS711</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL41 family.</text>
    </comment>
    <dbReference type="EMBL" id="HBGZ01000953">
        <property type="protein sequence ID" value="CAD9571559.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S2KAW4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019189">
        <property type="entry name" value="Ribosomal_mL41"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21338:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21338">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN L41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09809">
        <property type="entry name" value="MRP-L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CAD9571559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1737102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="150" mass="16565" checksum="F8054C1B18DAAF19" modified="2021-06-02" version="1">MAWRNSIASLASRVPAQQISCTISSSVRHQSTMAVNNNSSNLLKRTNNYAPLLNSASSLESRRFMSKYLTKAATKRLPLTNKKVKKGYYKGNGATVEGRITSKGKFIADPMKKLQLVVPDLEGFKLKPYIASAVSKLPPEQRTDEMMVGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XR84</accession>
    <name>A0AAD8XR84_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NADH dehydrogenase subunit 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_017093</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="mitochondrion" evidence="8"/>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Component of the iron-sulfur (IP) fragment of the enzyme. Component of the iron-sulfur (IP) fragment of the enzyme.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the complex I 49 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000083">
        <property type="protein sequence ID" value="KAK1732052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XR84"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.645.10:FF:000005">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.645.10">
        <property type="entry name" value="Cytochrome-c3 Hydrogenase, chain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01358">
        <property type="entry name" value="NDH1_NuoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001135">
        <property type="entry name" value="NADH_Q_OxRdtase_suD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014029">
        <property type="entry name" value="NADH_UbQ_OxRdtase_49kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022885">
        <property type="entry name" value="NDH1_su_D/H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029014">
        <property type="entry name" value="NiFe-Hase_large"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01962">
        <property type="entry name" value="NuoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004739">
        <property type="entry name" value="PRK06075.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11993:SF10">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11993">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 49 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00346">
        <property type="entry name" value="Complex1_49kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56762">
        <property type="entry name" value="HydB/Nqo4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00535">
        <property type="entry name" value="COMPLEX1_49K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 6" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NADH-quinone oxidoreductase subunit D" evidence="7">
        <location>
            <begin position="128"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00057195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1732052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="398" mass="45781" checksum="DF134BD218AFB357" modified="2024-05-29" version="1">MTLKKKNLLKKIKNFTINFGPQHPAAHGVLRLVLELNGEIVSRADPHIGLLHRGTEKLIEYKNYVQALPYFDRLDYVSMMAQEHSYCLAIEKLFNCKIPKRAQYIRVLFAEITRILNHLLAVGCHAMDVGAMTPFLWAFEEREKLMEFYERVSGARMHAAYFRPGGLQVDIPKGLLDDIYMFTEQFTLRLIEMEDMLTENRIWKQRLVDIGVVTADDACQWGFSGVMLRGSGVHWDLRKSQPYEIYDKLKFEIPVGTNGDCYDRYLIRVFEMKESLKIIEQCLNSMPLGYIKTNDFKISPPTRSEMKQSMEALIHHFKMYTQGVIIPSSETYIGTEAPKGEFGVYLVSDGTNRPYRCKIKAPGFNHLQALDFMSKGHLIADVVTIIGTQDIVFGEVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XS47</accession>
    <name>A0AAD8XS47_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">YqeH family GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_016911</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000068">
        <property type="protein sequence ID" value="KAK1732376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XS47"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01855">
        <property type="entry name" value="YqeH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050896">
        <property type="entry name" value="Mito_lipid_metab_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048422">
        <property type="entry name" value="NOA1/YqeH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46434">
        <property type="entry name" value="GENETIC INTERACTOR OF PROHIBITINS 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46434:SF1">
        <property type="entry name" value="GENETIC INTERACTOR OF PROHIBITINS 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21516">
        <property type="entry name" value="YqeH-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042160974" evidence="2">
        <location>
            <begin position="21"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="domain" description="SAP" evidence="3">
        <location>
            <begin position="97"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="786"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="787"/>
            <end position="806"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1732376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="806" mass="89047" checksum="F16076E31B6F0155" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSK0</accession>
    <name>A0AAD8XSK0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Kazal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016511</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000057">
        <property type="protein sequence ID" value="KAK1732799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSK0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00104">
        <property type="entry name" value="KAZAL_FS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002350">
        <property type="entry name" value="Kazal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036058">
        <property type="entry name" value="Kazal_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00050">
        <property type="entry name" value="Kazal_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00280">
        <property type="entry name" value="KAZAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100895">
        <property type="entry name" value="Kazal-type serine protease inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51465">
        <property type="entry name" value="KAZAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042223862" description="Kazal-like domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="2">
        <location>
            <begin position="102"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="153" mass="16583" checksum="56982332D77828CC" modified="2024-05-29" version="1">MRFFTIIATALLLSSEACAAQVLEEAKTQRLRKVKIYSSSSIRRGELSSGDVDPYLGLPDEREERHLQEEGGVSVAIASMPDNLSFSLPTSTTTTTEAPAFCIEIYKPVCGEDGITYSNDCFARLANVAVSYEGECLKEIPESPATATVLPII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XT18</accession>
    <name>A0AAD8XT18_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_016192</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000054">
        <property type="protein sequence ID" value="KAK1733054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XT18"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050966">
        <property type="entry name" value="Glutamyl_endopeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15462:SF19">
        <property type="entry name" value="PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15462">
        <property type="entry name" value="SERINE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042251921" description="Peptidase S1 domain-containing protein" evidence="4">
        <location>
            <begin position="36"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="218"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="371"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="232"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="377"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1733054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="680" mass="74773" checksum="1557A24E35E9D7C9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUD7</accession>
    <name>A0AAD8XUD7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015334</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1734076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUD7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="137"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="455" mass="49999" checksum="5A6BFAC97DFB6E65" modified="2024-05-29" version="1">MYKLIESHADAPSETDSYERASAFLFGWIEDSLLVPTAKAAQPPQRHRLLSPPGLDLPLPSSRALRRRITVSNGDNINSLTSLMLHEHQNQNRPTNHSARVRLNLSPTYVGTVLHKEPSSRRGRAAIIPTLPFCKRPQQPSVPSSSNPPGRDHQQGGVPSVRSASAAPSQTRRHSRTIPCSSLRHRSSSGGGQRRRSCDDTPSTSQSEDVKKKSGPNKHRSKSSKNHVGNVGHCTGQMNTLAQPHGSGAFSTAHTSSPESSPVPSPVAEKEVIKRAVSDTVEVMKTAAATAKDDEPPSRKSGEDKKSCAESLNRPTKTKSSRKKSRRHTMAGDPSATTKPSSSEVSLPLDRLSDLDGPNFDLGDTLRSPKQQIIESNPNKALNLISQLRIHDFAWILRSSREWTYGIVADFPERGEESSIRFVIDKVGNTKTFKMKHWAKCIRLVDDKLQSQKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUL2</accession>
    <name>A0AAD8XUL2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_015184</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUL2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="190"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1734181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="266" mass="29738" checksum="08903BE9C5F4EC5D" modified="2024-05-29" version="1">MPSITQQQMYGRQRRSKTCCGYCGVPAGLRSQCEITEVCRIVSASFSCCCERDHTDSGIIEVALEIVKILYDAHSEAIEDNLFVLNIQSFHEQIQSFINTQLFYSRQARDHRQMTAPDEKGQLPLHTALENNARLGSIKLLMKGNPLAVQSPDNSGALPLHVACEHHDSPSVVQYLIGLDTTTLDAVDRDGNTALHYACRSAKYDMIALLLDKYDAVSVSKRNAQKKLPIDLLWESNEVLDRGSIEHTESVFQLLKAYPEIVTTLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUY1</accession>
    <name>A0AAD8XUY1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUY1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="267" mass="30317" checksum="24598289A67D9A94" modified="2024-05-29" version="1">MTIEEKFRGFYSNFGIEQDPGKMRHLFDELYHDDFKNELDGTHTLDKVQLWKLQTIVIKNGTVATVLMFKNAKPNVVEYKIHFKGTDELVGKTVHCAYELMDGKICRGRAVDESSITTISKATTATANFNQVQKSAQALFTLFDGVPRPFDEELNKAFEALYHQDFVHNMDGEPLNKAQWRERLNTFAETGTRILLLKFEPKDEVHFEAGIRVINKNIDVVGYSRGTISGSTLLKIEPDEQSKSSYAMMPGQKVVLAEEHTHIAIAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW48</accession>
    <name>A0AAD8XW48_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014562</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XW48"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041988514" description="Thioredoxin domain-containing protein" evidence="1">
        <location>
            <begin position="28"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="74"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="139" mass="15810" checksum="FADB88C20EEFA20A" modified="2024-05-29" version="1">MARKYLITAAAAVCIIILASVPQCCQSFTTTKHEVHPTISISKRRNASQQLQMIFRDLVSNDEIDLRVSITSIQKKDEFEKFLQEDDRLCVIKFYAPFCKACKAFGKKFRKLAIDRGDPINSIGRLQGMVMLALVRLIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWA0</accession>
    <name>A0AAD8XWA0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014486</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWA0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="150" mass="16733" checksum="0200477423B2BB2A" modified="2024-05-29" version="1">MSAATQRSAGVISRFFFHSAYPTLKLGSQRPLKEDDLPELGKLESPRHNRLKIEKVWAEEVKSGRMNLGRALLADFITSTWKAQLLAFINFLARIGQAYALGLLMEEFGRYDSNAASMSEKVVDAKMAYIYAGLLTVCGLIAFPSKQHSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXJ0</accession>
    <name>A0AAD8XXJ0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_013432</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXJ0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="269"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1735726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="327" mass="37015" checksum="798D45D3AB781E18" modified="2024-05-29" version="1">MPSKKKARGKARARRVAKSRKAMEEDAAVNVTAQIQRLQIGHNNINEDEDEDEDALLAKAINLAAAEKYELKAAAAAKNDEANNSEDCLHGFDTLPEDHVCGAFIESFIHNFFAGSESSNSLLDGFDNSYEATKIKYAEVWNDADNLDGFVNVYEATRRKYAEVWNDADKMQLVVDFFVCNGTKKILFDGHSDRDCYDAIFASFLEQVIAVNIQKTQASHDWGKIAEVKCDEHTLVSFFRKRIPCKCLDESYKEVKSITKMGLCHNLSCSLPDRTAERSKMLSCTRCRRANYCSRECQKAAWPLHKQNCGIRTGRLDELLSRQIEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYE9</accession>
    <name>A0AAD8XYE9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_013478</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYE9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF80">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041911046" evidence="7">
        <location>
            <begin position="20"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1735772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="265" mass="29162" checksum="867379BFF7C930CC" modified="2024-05-29" version="1">MNRLSVLLLACSLAGSTTSAFTTPSRGGSLLHQTPSRYVPSHQDLFTRPRGRSHTTTSSKRHTKLSAALIPPGKFTAIGMGIGKFYKASPLIAGFLTASTKACFADSMAQYRDTGTTKFDIKRNLAMVLYSGTILGLCCAVMYNQVFPIMFAGETNPLLLAIKMTLFDGFINAPLIWLPPAYIAKALIYNQPKREALQKYVTDVKENGLLKKYWSLWLPASLTNFLFVPAHFRVAFVAGVSFFWMIMLSIVANNNDEEEVVVEGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYP8</accession>
    <name>A0AAD8XYP8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013616</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYP8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112:SF15">
        <property type="entry name" value="HMG BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="138"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="244"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="142"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="267"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="305" mass="34222" checksum="7D2DC295A50B3664" modified="2024-05-29" version="1">MERPKRPLSSFNLFYRYKRSLVLEKVGDGAKDDVLRILSATAGLEETPLEANQQPPFSDEINTLRRNRIREALRNKITPNDNGKRRHRKAANSLGISFSEMGKLMTTCWKGVDPFGKEVFEELSEEGRHIYRVQMDEYNELNPKEEPKKSTPDKPKLNNNRVRKQSVRSQYEALEKAVAAAGHAATFPAAAAFPAAPLPHGVSIPVQMLAHHNRMAAFQRIPSMMATTNPSFIMPVAQFNPIMASRQPPSYGRTNEMKREAKPSRRAAANMDILAAAAAAAAEPKRTPPTEPTRSLPLKKRFKRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZD7</accession>
    <name>A0AAD8XZD7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transcription initiation factor TFIID subunit 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_013296</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZD7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.500">
        <property type="entry name" value="TFIID subunit TAF5, NTD2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007582">
        <property type="entry name" value="TFIID_NTD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037264">
        <property type="entry name" value="TFIID_NTD2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879:SF1">
        <property type="entry name" value="CANNONBALL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04494">
        <property type="entry name" value="TFIID_NTD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160897">
        <property type="entry name" value="Taf5 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="TFIID subunit TAF5 NTD2" evidence="9">
        <location>
            <begin position="413"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="824"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="958"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="993"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="105"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="278"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="343"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="516"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="858"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="135"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="170"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="343"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="516"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="528"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="859"/>
            <end position="885"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1736160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1150" mass="123020" checksum="D644AA3DA0282C12" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y080</accession>
    <name>A0AAD8Y080_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_012568</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y080"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010291">
        <property type="entry name" value="Ion_channel_UNC-93"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051617">
        <property type="entry name" value="UNC-93-like_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23294">
        <property type="entry name" value="ET TRANSLATION PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23294:SF59">
        <property type="entry name" value="UNC93-LIKE PROTEIN C922.05C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05978">
        <property type="entry name" value="UNC-93"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="373"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="407"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="281"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1736546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="541" mass="59932" checksum="1BF404AC0F9487EE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y085</accession>
    <name>A0AAD8Y085_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">lipoyl(octanoyl) transferase</fullName>
            <ecNumber evidence="3">2.3.1.181</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_011945</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LipB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.181" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y085"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033819">
        <property type="term" value="F:lipoyl(octanoyl) transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16444">
        <property type="entry name" value="LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00013">
        <property type="entry name" value="LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000544">
        <property type="entry name" value="Octanoyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020605">
        <property type="entry name" value="Octanoyltransferase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00214">
        <property type="entry name" value="lipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10993:SF7">
        <property type="entry name" value="LIPOYLTRANSFERASE 2, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10993">
        <property type="entry name" value="OCTANOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21948">
        <property type="entry name" value="LplA-B_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01313">
        <property type="entry name" value="LIPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="6">
        <location>
            <begin position="168"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1737078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="358" mass="40546" checksum="A640FBA94D8827D9" modified="2024-05-29" version="1">MVQKTRHPICHQQQFITCARPSLVKRMHSYNHVSMIIMQAFALCLLLSLLKLQLSVVAFTSPTKCVSRCHYQLLHLAPQQLGEFKPINLVGDEEKQIDRSTRRVWLYDFVSHTQQDDRIPYEEAWDLQKRLMEQQLSRIGKRPKDPPLYDQFVPLDVNKKEGIASNSLVGCDSIIMLQHEPVYTLGTASDTSFIHDYDDNGDNESRIPIVRIERGGEVTYHGPGQLTVYPILDLRGYNQDIHWYMRALEEAILLALEKAGVAGATREEDVTGVWVSNKKIAACGVKLKRWVTMHGVAVNVDIRSLENFEGIVPCGLEGREVTCVNDAIDGKQYTLQEFAIHMKAALEEIFGITLLSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0G6</accession>
    <name>A0AAD8Y0G6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">JmjC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0G6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016706">
        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045905">
        <property type="term" value="P:positive regulation of translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050910">
        <property type="entry name" value="JMJD6_ArgDemeth/LysHydrox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480:SF6">
        <property type="entry name" value="2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE JMJD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480">
        <property type="entry name" value="ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="1">
        <location>
            <begin position="249"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="518" mass="58940" checksum="1CBBB75B199FC8A8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0L5</accession>
    <name>A0AAD8Y0L5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0L5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="645"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="666"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="740" mass="83985" checksum="7EDB54C47E0E53D0" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1E6</accession>
    <name>A0AAD8Y1E6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">G protein-coupled receptor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_011689</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1E6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="343"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="363"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="385"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1737403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="409" mass="45828" checksum="B576BBA95D678734" modified="2024-05-29" version="1">MVSLSDPKCQITLLKAMAIAPKVTAIISLFSSTFIIQHVLRDRKRRSLTYHRLLLGMSISDFFGSLMCFLSTWPIPRGEACLAAGTTATCTAQGFFNQTAALCTITYNVSLAIYYILVIVKGWKGTRVSKIEKYLHALPILAGFGTGFAALGLKLYNNSGSTCWIAPAPNNPDRHNPNYGIYRLAFLYADAWAIIIFLAICMTIIYFHVLKQEKKLDKYSASFSQKKRKQSKKIRNQAFLYVGCMYMTWIFGSAFRFMQFAGKTPPPYIIVLFVTFFPLQGFFNLVVYMFPRILRYFEEGVPLTQSFKRTKSSFFTSLKNTVRKRRTPTQTQTQTQALETQVSCDEGNVETGENGEKGAALEVDVDVGDKEEGEGTSGENKIEEGDSSEDDEGDGEKDAIDELECIVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1I1</accession>
    <name>A0AAD8Y1I1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011555</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1I1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="105" mass="11184" checksum="2DE4CB5E68209AD9" modified="2024-05-29" version="1">MVGHTTSSESMTGSADYWNTIKSILDSAASASGGSGNLTSMEEQLYNAIYEANDNNGEANEYNDQVATTLTNGVMDLYKSGLLNDLDTPLQFGKCSLQEASDTKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1Z8</accession>
    <name>A0AAD8Y1Z8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012227</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1Z8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="70"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="108"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="263"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="166"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="186"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="206"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="404" mass="43320" checksum="200573B6A1D2FB9A" modified="2024-05-29" version="1">MLKMSRSRSTKITSNDVAKPIIYEDAHKTAANEAYAVEEDSRNEEPEDCATFLLDELAQALFGVYENAENGACLDGRDGPEVESEDGTEGNETTTTCLQKDEVQNLSQATTSVTKTDEKNGEEAKMAAAAREKAQIEAAQAKKAAQEEEVKKKAAARKQAKIEAAQAKKEAKKEAKKAAAARKQAKKEAAQAKKAVQREAKKAAAARKQAQIAAAKAKKAAQNEEAKMKAAVVAAHKQAQIEAAQAKKLEEVAKKAAAAAAAAAATAAALNQAQIEAEQAKRTEQEEAKKAAEMEAARILLNQLEAEQKLLKEAEKKQVIPEENTLSLSCTSLEASEVTSLDSEDSEDTHMTILTVLRGGLFIKQQQGYSTEMSSCVDEAKIDELPHFHSTASDSSADTNVPFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2M1</accession>
    <name>A0AAD8Y2M1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_011343</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2M1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044508">
        <property type="entry name" value="At5g50450/At1g67340-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46758">
        <property type="entry name" value="MYND DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46758:SF19">
        <property type="entry name" value="ZINC FINGER, MYND-TYPE, TETRATRICOPEPTIDE-LIKE HELICAL DOMAIN PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="57"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1738049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="251" mass="29186" checksum="A9E04D9F4AA930C1" modified="2024-05-29" version="1">MANISEDYLDSLPADERAEFLNDVFSMLSMDPSKKDETMAQNIRKMYAGHEGNVVKCSFCRKDEPDDQEFGECSGCGLVLYCSKECQRSDWKLSHKVECGKLLDMFRLFNKEMNAGDVLFPAEFFVDIHLADLPRGTKRPRLYIKHAMIGKLSKRVLDVVYSRMKPPERGYESVRYCLSYSFGPGENDNISSYRQFHYKMGPNKLRRLKRSTKNVYEENVDEHMNMINSIARGESPRMYKVIKEIMKEKFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2R3</accession>
    <name>A0AAD8Y2R3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2R3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="1">
        <location>
            <begin position="423"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1268" mass="143622" checksum="813E97FA82627947" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2T6</accession>
    <name>A0AAD8Y2T6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Protein-S-isoprenylcysteine O-methyltransferase</fullName>
            <ecNumber evidence="10">2.1.1.100</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_011447</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.100" evidence="10"/>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2T6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004671">
        <property type="term" value="F:protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007318">
        <property type="entry name" value="Phopholipid_MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12714:SF26">
        <property type="entry name" value="ISOPRENYLCYSTEINE CARBOXYLMETHYLTRANSFERASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12714">
        <property type="entry name" value="PROTEIN-S ISOPRENYLCYSTEINE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04191">
        <property type="entry name" value="PEMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="91"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="163"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1738153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="232" mass="25248" checksum="6E5EE7959256CA95" modified="2024-05-29" version="1">MKGFPIPLILAFTSSATRRASAFVPQPLALNNGRNYQVSTNKLLATEKKDDVSNNILSSLQLPSPEAVKENILEGNVGERGETYVVAQFSLLFFIAIGVGDVVTTILGPVFIIAGLILVYKSAADLKDNLSPWPVATDPKAGRGSLINEGIYSYIRHPMYAGLLLGMTGLSILTDSITRLLLTFALYLVLDAKSDFEEASLVKTYGSDYGEYKAKVKSKFFPLDVNSVFTNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3K3</accession>
    <name>A0AAD8Y3K3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3K3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="100"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="196"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="241"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="292" mass="30318" checksum="92488516BB603D7A" modified="2024-05-29" version="1">MHTQAEAYCSHYNCGDVVCNSFTKRRVWSSSWSWGGGGRKPTRRPSPSPSSNKWGWSWSWGGSSSPWSSGWGGESSPTHWVINGWAEGSWTGDGWSANKPTTSPTRAPVVVTPRPTTSPTSAPVVSEGERTSSPTTSPTTAPVARTPQPTTSPTRAPVARTPQPTTSPTSAPVIVAPRPTTSPTSAPVVPTPQPTTSPTRAPVARTPQPTTSPTSAPVIVAPRPTTSPTSAPVVPTPQPTTSPTRAPVARTPQPTTSPTSAPVIVAPRPTTSPTSAPVVPTPQPTTSPTRAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3N5</accession>
    <name>A0AAD8Y3N5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="17">ATP-dependent zinc metalloprotease, FtsH family</fullName>
            <ecNumber evidence="17">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">QTG54_010648</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="17"/>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3N5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19501">
        <property type="entry name" value="RecA-like_FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000277">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076:SF97">
        <property type="entry name" value="ATP-DEPENDENT ZINC METALLOPROTEASE YME1L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076">
        <property type="entry name" value="METALLOPROTEASE M41 FTSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 17" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042264394" evidence="15">
        <location>
            <begin position="30"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="16">
        <location>
            <begin position="368"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1738618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="631" mass="68126" checksum="2FB57958A4EB3A30" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3N9</accession>
    <name>A0AAD8Y3N9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sel1-like repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3N9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042229926" evidence="2">
        <location>
            <begin position="18"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="319" mass="35047" checksum="7F0C1E0B017998F6" modified="2024-05-29" version="1">MMFRLLLLLCHAMVTVGFISICSSVNYDHHHLSLSGDDGQACDEDTIITLPLDISCDVRLVAEDLWGSPESVGSILMSSDHINDSGIILCHPDCQGEMPLPSSIPISQRFSYFEQQAQKGDPRAQHSIGLLLWNGFTSSTEQTSIDPEASARWHAAAALQGNLDALAVFGGCLRTGTGVGKCKNIALGLRCIDYSASVGNPSGVNKKGVMMESNDDYFGAMRLYRECYEDESKRTNALLLFNFGYCLIHGDGVDNDVEEGEKIWKDAVALAPEEGSEEAAWFLYQQYSERGDMEKARHYLDIAADLGLEDAVMERRDNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3V1</accession>
    <name>A0AAD8Y3V1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4336 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_010465</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3V1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025638">
        <property type="entry name" value="DUF4336"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835:SF1">
        <property type="entry name" value="METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835">
        <property type="entry name" value="YALI0C07656P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14234">
        <property type="entry name" value="DUF4336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1739149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="232" mass="26541" checksum="F7A94FDC24414ADE" modified="2024-05-29" version="1">MALLNFAPNIYIQEYPIRYAGCHFNSRMTIIKLSTGQLWIHSPCEITPQLKSEIEALGPVGVIIAPGNYHHLHISSCQNAFPSAQTFICPGVEKKQPKLKYDAILHETKPEEAYAADWEQVLLQGNRVINEVAFLHQESKTLILTDSIELIGDSTPGTNWVLRFWWKYLLRMWNVPKPAPEYQMGWNNKALAKKSMERIMQWDFEQVIISHGDNITKDAKNVVHSAWKSILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3Y6</accession>
    <name>A0AAD8Y3Y6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010730</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3Y6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026913">
        <property type="entry name" value="METTL24"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32026">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32026:SF10">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 24-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13383">
        <property type="entry name" value="Methyltransf_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="80"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="384" mass="43866" checksum="A3E8CF5EBAC26BC7" modified="2024-05-29" version="1">MMIAADEQVAFRPRYSADESSNEAYAEDLRQQRFQGRKRRFYAVIILIIGFISVTVIFRIYYFIAGDIITVDGSIKQNSLAKKESFGFFDDIPNNMWKEKKSASKKAVKLQNKIITKTSNMLFESGANVDERKWWEQNWLPNFSCDNKMFIGGKWICEPSRIIDLADEHRDVIGRKKKRQRGRKECLIYVSGGNDVEFGHQFSSFVEARMAELHKDEPGVDLSICEIHIFNHFIDPALLANMVQQGKGIHIHPFGFRPENKESMGVAGDGSATAFKTFKETVKELGHTGKSLSILAIDCEGCEWDIYKEVLSSDVTVLQVFFQMHGTPFMANRFFVAMHNAGYAIFHREEVGVSVYDYSFLKLAPSYFGSTKPQLRQPPNTPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4K3</accession>
    <name>A0AAD8Y4K3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Origin recognition complex subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010384</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4K3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="796" mass="88529" checksum="B94BBBA95CCE1545" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4L3</accession>
    <name>A0AAD8Y4L3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Centromere/kinetochore protein Zw10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010268</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4L3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990423">
        <property type="term" value="C:RZZ complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046362">
        <property type="entry name" value="Zw10/DSL1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055148">
        <property type="entry name" value="ZW10_C_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12205">
        <property type="entry name" value="CENTROMERE/KINETOCHORE PROTEIN ZW10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12205:SF0">
        <property type="entry name" value="CENTROMERE_KINETOCHORE PROTEIN ZW10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22766">
        <property type="entry name" value="ZW10_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ZW10 C-terminal helical" evidence="2">
        <location>
            <begin position="756"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="908" mass="100333" checksum="C4CC5A8EEE9FCAE2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y520</accession>
    <name>A0AAD8Y520_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Trypsin-like serine protease</fullName>
            <ecNumber evidence="8">3.4.21.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_009462</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y520"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000002">
        <property type="entry name" value="Transmembrane protease serine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF91">
        <property type="entry name" value="AT26814P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042117278" evidence="6">
        <location>
            <begin position="21"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="7">
        <location>
            <begin position="43"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="269"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1739703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="440" mass="47769" checksum="78826E06DCD08646" modified="2024-05-29" version="1">MKLSKAIILLLSASTTSTSAGNLRSSKNINNNVKERDLKNTRIIGGDEAVENRYGYAVSLSDDWGHFCGGSLIARDVVLSAAHCDDQGKGNYNAVVGRHSLDDKDGQKLSVRKAMPHPDYDSDTTDNDFMLIFLKEAAMTVMGWGDIDPSDEQELSGELMEVEVNVISNDECDDSDGKFGSYEDQITSNMLCAREEGGGEDSCQGDSGGPLVIKGTDQNGADDTQVGVVSWGIGCAEKDYPGVYARISSEMDWIKSEVCKGSKNPPTSFDCDRSIGDSDNSSTTSGGSSTTDSSPSNGIWKTLVADEFTKDFGIFAGDSKGAVKYVNAEGKNGVIRMEADGKSTLKSEKIKVDKSDERFRVSVDAYLVKMTQEDNICVDYQTKKGKGEQCWKGSQDAQWTTNTFEFEDKDAKALKFRLRLDSKSKDSALLVAAFKVETSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y571</accession>
    <name>A0AAD8Y571_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009822</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y571"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042245623" evidence="2">
        <location>
            <begin position="21"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="268" mass="29069" checksum="5B570285D256E27C" modified="2024-05-29" version="1">MTATRLFLTAAAVMLSSAAAFNTIQPRMIATRTQTNNKSSVVSFMSSSSNNNNEHQNHFTSKPIVSTLTALSIFATLSTTPLLPNTNSAANAYEESDYASETVTTVVQRLKSSTGSIDDTFLALEDVAKIITEGKGVGGQLTYDGVKLNEGYVADEDTTIYNPGLSLLTESEKERLTDAIIQNRKVSLSSNQWNENNEYAFKFLKQKLDPLHMFELGGYLKILPFWGAALYLGALFVQQNSRGIFPLVYGLCALGVFGPVIVLVASGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y667</accession>
    <name>A0AAD8Y667_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">HEAT repeat-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_009697</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in nucleolar processing of pre-18S ribosomal RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
            <location evidence="1 7">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the HEATR1/UTP10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034455">
        <property type="term" value="C:t-UTP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045943">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012954">
        <property type="entry name" value="BP28_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040191">
        <property type="entry name" value="UTP10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13457">
        <property type="entry name" value="BAP28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13457:SF1">
        <property type="entry name" value="HEAT REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08146">
        <property type="entry name" value="BP28CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01036">
        <property type="entry name" value="BP28CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 7" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="BP28 C-terminal" evidence="9">
        <location>
            <begin position="2196"/>
            <end position="2365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1506"/>
            <end position="1529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="2322"/>
            <end position="2344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="2335"/>
            <end position="2344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1739938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2528" mass="273608" checksum="48D009EFD32B9E49" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6G5</accession>
    <name>A0AAD8Y6G5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008714</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6G5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="122" mass="13684" checksum="D1D3C6E59F9CF8F0" modified="2024-05-29" version="1" fragment="single">MPPDANIVVIRNEHIVDDWNAVETLLGGAADLTKESLPVNNQYEKKPEEVYLSDAAKVVLCETLCNEIQVYKTILKRAQNINKEQYIQSMQELVTSCPKEAMEESCADDMPDISLKVEKAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y717</accession>
    <name>A0AAD8Y717_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Prefoldin subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008168</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y717"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051131">
        <property type="term" value="P:chaperone-mediated protein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23161">
        <property type="entry name" value="Prefoldin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002777">
        <property type="entry name" value="PFD_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21431">
        <property type="entry name" value="PREFOLDIN SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21431:SF0">
        <property type="entry name" value="PREFOLDIN SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01920">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="99" mass="11443" checksum="C48B6F69DB0035D6" modified="2024-05-29" version="1">MTTNIGAQAADAVNDKLVERQKLEQEMYAHHQDLQTLISQRNENEMVKEELEICEKESSDATIYKQVGPVLLKNDLSDATDTIEKRLELFRVRLKRLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7N5</accession>
    <name>A0AAD8Y7N5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7N5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="537" mass="61524" checksum="FB67D60D6FCE2469" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7Z1</accession>
    <name>A0AAD8Y7Z1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cell division protein FtsZ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_008526</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FtsZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7Z1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048285">
        <property type="term" value="P:organelle fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02201">
        <property type="entry name" value="FtsZ_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000001">
        <property type="entry name" value="Cell division protein FtsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00909">
        <property type="entry name" value="FtsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000158">
        <property type="entry name" value="Cell_div_FtsZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020805">
        <property type="entry name" value="Cell_div_FtsZ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024757">
        <property type="entry name" value="FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00065">
        <property type="entry name" value="ftsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="CELL DIVISION PROTEIN FTSZ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314:SF3">
        <property type="entry name" value="MITOCHONDRIAL DIVISION PROTEIN FSZA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12327">
        <property type="entry name" value="FtsZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00423">
        <property type="entry name" value="CELLDVISFTSZ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01135">
        <property type="entry name" value="FTSZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041923545" evidence="5">
        <location>
            <begin position="28"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="6">
        <location>
            <begin position="138"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="7">
        <location>
            <begin position="334"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="44"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="98"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="100"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="113"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1740431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="461" mass="47708" checksum="B4468925EFE70154" modified="2024-05-29" version="1">MVKSFLSTATYCAIAVVAISTTQTTSAFQTIRPSLVYKTAATSSSLNNNSNLNNDEVSVGSGSSPLQGVVNEGPRSLAPNRTFLGMRRESGILRRMTEEMSGSTSNTQQQARTTTKSTTSLSSTPTALMPDGGLSPCVIKVLGVGGGGSNAVDRMLDTRISGVEFWAINTDAQALGRSKAKGASVLNIGSAVTRGLGAGGNPEMGRLAAEESREEINAMVEGADLCFITSGMGGGTGSGAAPVVAEVSKESGALTVAIVTKPFAFEGRRRMRQATEAIDRLRQHVDTVIIVSNNKLLDIIPENTPLEASFRVADDILRQGVVGISEIIVRPGLINVDFADVRSVMQDAGTALMGIGTGTGKTSAEDAAVAAISSPLLDAPVDEATGVVFNIIGGESLSLQEVDRAAQVIYNNVHEDANVIFGALVDDEITDGTVSITVLATGFYEEGGNGGGDGGIPDFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y802</accession>
    <name>A0AAD8Y802_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RCC1 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008434</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y802"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028641">
        <property type="entry name" value="RCC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46207">
        <property type="entry name" value="PROTEIN RCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46207:SF1">
        <property type="entry name" value="PROTEIN RCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="216"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="446"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="551"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="101"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="631"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="101"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="631"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="653" mass="66841" checksum="ACE54BA59270F0E9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8B7</accession>
    <name>A0AAD8Y8B7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_007257</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8B7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000003">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008047">
        <property type="entry name" value="MCM_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF66">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21128">
        <property type="entry name" value="WHD_MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01660">
        <property type="entry name" value="MCMPROTEIN4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="13">
        <location>
            <begin position="633"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="215"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="579"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="667"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="8"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="147"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="223"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="249"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="579"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="590"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="669"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="686"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1741684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1085" mass="119394" checksum="03DE3F2B8321D410" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9F6</accession>
    <name>A0AAD8Y9F6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase</fullName>
            <ecNumber evidence="3">2.5.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006831</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9F6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03192">
        <property type="entry name" value="GST_C_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF150">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="89"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="220" mass="24127" checksum="B99D126691D1405A" modified="2024-05-29" version="1">MTNKFHYYAATGRGHAIRLALSAANIPFEDEYPEGGFPPTAEAKDLWRSIGKNTTTNIPMLQMADGRVFTQSSAVLRAVARIGGLMPTDEGELYMTDKLLADAEDLRGEGYKSFVAWGATEEAVEAFINKVLPLHFGNLERQLKESTGDYFIGDSLTIADIACYDAITNFGSNRVIGSLDGFETLKAWVDKVESNEGIKNYMSSESFAGLWKFGPDTLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAH7</accession>
    <name>A0AAD8YAH7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAH7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="520" mass="58719" checksum="75FA81F8D232A4D7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAI5</accession>
    <name>A0AAD8YAI5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAI5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="103" mass="10546" checksum="D7FD766A5936640D" modified="2024-05-29" version="1">MGSHWGAYGAATGARMGQPLGARMGQPLGARMGQPLGARMGQPLGARMGQPLGARMGQPLGARMGQPLGARVGAGERAQHPSDPPLSMPGRHLSNPKIEAMIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAL2</accession>
    <name>A0AAD8YAL2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">STI1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAL2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="129" mass="15097" checksum="4B68384DCCBAE6E4" modified="2024-05-29" version="1">MSSGQFNPFGSDMMLAQLMQDMQDPEMMREAQTMMNDPAFQERMKTLTDNPNFKEHMEQTTETMKDPEKQKEMEEKMKARVTAGQKELEDFKKKSAELEAEEKRKKENAKKKKNQKPKTSSKKKGVKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAV0</accession>
    <name>A0AAD8YAV0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein LSM12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1743034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAV0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047574">
        <property type="entry name" value="AD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039683">
        <property type="entry name" value="Lsm12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019181">
        <property type="entry name" value="LSM12_ABD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13542">
        <property type="entry name" value="LSM12 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09793">
        <property type="entry name" value="AD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00995">
        <property type="entry name" value="AD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52001">
        <property type="entry name" value="AD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AD" evidence="1">
        <location>
            <begin position="95"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS52001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="203" mass="22156" checksum="A79E54EF03833FB0" modified="2024-05-29" version="1">MAAATTTQTLPLSSIYPINTLMELTLNNNNSKEVTTGTIYCTDEVSNTIVLKKSLVHTTLTSEITVINAAVVTDRRIITAATAADEKEGEKTVLPNVSRRMVEERERRAIKLMEESFSHVNQQASPEGQKIFDKLLKACNEVSWRGESIIVLGEIRVDPPYTSNDCVLIGKGGGLDGHSLERVKNIVNAAAVKYNHGVSGSRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBU6</accession>
    <name>A0AAD8YBU6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBU6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="141" mass="16276" checksum="0B9C4F5D647BFCA8" modified="2024-05-29" version="1">MHQKDIAALSDEEEENLQEFMLNLAILFIFMSIIGIISCVYQIKPYQSIRRKHSHESTLQSAAHIQNQAECVYKMKAATESSRADMQDSLEREVEELRAFQQQVRGELGTLKTALTVLSQRRQREVLRPDDAESHRKGKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCR1</accession>
    <name>A0AAD8YCR1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HSF-type DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_005761</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCR1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF206">
        <property type="entry name" value="HSF-TYPE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="6">
        <location>
            <begin position="110"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="376"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="72"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="387"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="406"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="420"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1743140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="430" mass="46783" checksum="7F329996AB66332E" modified="2024-05-29" version="1">MPVDINKSPDNNDDGSGRDAEHQNEEPSSSEIRTSAAPFATSASIALPLADNTSEDDQKPAAKEYASSDGMTTTTTQSSTTTPPSLSTAPIQVTSKKRRENHEHEGRFSFREPFLEKLRLMLDNETNADSGSIQWLHGEDAFVILDQNKFEKDVIPKYFTPIIFQSFLRKLYRWGFKRITTTHAGRYKFASATFVRRPAPNTTLNGAAGTVDPIVPNNSALEMLLRQLPAANAQPNQLNTLALLAQLQQSLQPAVTQDNHLNAALVNALAQQALPQIQLRQQQQINQTQANSILQNLLAQQLVNQSMLQSVQSNAFSSAPNQNLMRSLAAASQAPLVSYLNQNQVLNANAPTLRTGPSSEQALSLLLSSIQNAATAAGANQDPGSAVGNTENSSSSATDDRRRMLPQSQTDSSSAQPQSQRKRKHPHPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDH4</accession>
    <name>A0AAD8YDH4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7640 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006121</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDH4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019524">
        <property type="entry name" value="B-solenoid_diatom-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056057">
        <property type="entry name" value="DUF7640"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22534">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22534:SF5">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24646">
        <property type="entry name" value="DUF7640"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7640" evidence="3">
        <location>
            <begin position="305"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1743500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="504" mass="52933" checksum="365FEC986F64AE7D" modified="2024-05-29" version="1">MTVSSMEHFDDEVLDEHITNIIANQHLAPPPAHAFVSNDEEECVGELDDEEFQSSGLGDGENVKSIGDDEEEYMCDINGEDSQSSGLADEDEEIKSICGDEECVGEKEYQSSGLGDDETSGGDDEECVGGVLKSYQSSDHGDEGSAKSNGDYEFVGYIKNEENQSSELGAEEIPKVNNKKYGRWKIGAFVAVCSLVIISIAAGVGSSKRTDVNREGAGIGETASVTVVPQENGNETENENESENVSETLNDVDTPAPSICIAKQSFEIAMADEVEEFSCNMDKQCDGNADIGACVGNNGTICDGACNSPEACIDNQGDIQSCSCLGVDACNTNEGDVGLFACNGKHACKKNSGTIGTLSCNDHNRACFDNHGDVAPESCNGVKACLENDGSILLKSCNNLKSCHENTGPVGERSCNGQESCMKNVGTIGAKSCNGEKSCCGNTEDIGSNECNGDFECCNSDVSQCECPSQTNVTSTLGSLASLEEAPTNATLTTSSGGFGERNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDY6</accession>
    <name>A0AAD8YDY6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDY6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1743824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="27" mass="3055" checksum="FA57BE4181B2022D" modified="2024-05-29" version="1">MKNVIEYVGLQIQNAATYFTKIAFFSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFV1</accession>
    <name>A0AAD8YFV1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003976</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFV1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="149" mass="16783" checksum="0EF251FF25A84B3B" modified="2024-05-29" version="1">MSTPVSLILNINTMAIFFTRDNFVLAFPLLAVCSTYAFFKFIPLQYGLPVLGVIALTLKARNKIIESRSTDEHIDKTIVQDLVSDEDALIAKQNEKAQKKLRKSEQKLRERLKAERRNTANKKKEAADEDDDGEIITAFAKGARGKKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YG37</accession>
    <name>A0AAD8YG37_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003396</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YG37"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="269"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="626" mass="67950" checksum="203F43475CAAE94E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YG92</accession>
    <name>A0AAD8YG92_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nucleolar pre-ribosomal-associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005048</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000466">
        <property type="term" value="P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039844">
        <property type="entry name" value="URB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032436">
        <property type="entry name" value="URB1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13500:SF0">
        <property type="entry name" value="NUCLEOLAR PRE-RIBOSOMAL-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13500">
        <property type="entry name" value="NUCLEOLAR PRERIBOSOMAL-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16201">
        <property type="entry name" value="NopRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="URB1 C-terminal" evidence="2">
        <location>
            <begin position="2011"/>
            <end position="2247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="417"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1871"/>
            <end position="1936"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1959"/>
            <end position="1992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="109"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="232"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="440"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1892"/>
            <end position="1912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1969"/>
            <end position="1991"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2472" mass="273770" checksum="8A13EDDEE152517A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGA9</accession>
    <name>A0AAD8YGA9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nucleoside diphosphate kinase</fullName>
            <ecNumber evidence="9">2.7.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_003895</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:44640"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.6" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGA9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006241">
        <property type="term" value="P:CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006228">
        <property type="term" value="P:UTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04413">
        <property type="entry name" value="NDPk_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.141:FF:000002">
        <property type="entry name" value="Nucleoside diphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="entry name" value="Nucleoside diphosphate kinase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00451">
        <property type="entry name" value="NDP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023005">
        <property type="entry name" value="Nucleoside_diP_kinase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001908">
        <property type="entry name" value="PRK00668.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11349">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="Nucleoside diphosphate kinase, NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00469">
        <property type="entry name" value="NDPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51374">
        <property type="entry name" value="NDPK_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleoside diphosphate kinase-like" evidence="10">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="active site" description="Pros-phosphohistidine intermediate" evidence="7">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1745971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="149" mass="16358" checksum="E060BA304273C691" modified="2024-05-29" version="1">MERTYIMIKPDGVQRGLIGEIIKRFEQKGFKLVAMKLTSPGKAHMEEHYADLAGKKFFPGLISYMTSGPVCCMVWEGAGVVATGRKMLGATMPSESAPGTIRGDYCIEVGRNICHGSDAVDSANKEIALWFPEGISEWNSCQSSWIYEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGF2</accession>
    <name>A0AAD8YGF2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_005138</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGF2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032993">
        <property type="term" value="C:protein-DNA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="REGULATOR OF RPOS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111:SF1">
        <property type="entry name" value="TWO-COMPONENT RESPONSE REGULATOR ORR33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="131"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="234"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="263"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="286"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1744605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="560" mass="62595" checksum="44D35EDC966EAD12" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YH84</accession>
    <name>A0AAD8YH84_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_003299</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YH84"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="160"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="178"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1745375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="216" mass="24478" checksum="099A7DED9E6B1680" modified="2024-05-29" version="1" fragment="single">EYTKCGICITKFSSYRDNKNPEIRKHLPVLSSSQRCDHWFCHGCILREQLRVAEENIGRIPKWIKCMHCREKTSFNPAEPKYHRLLIDLLARAQKYAAAQVKNEEQESCVDMQLNLGSSSNAMFMKRECDAVDDDEGDREMKRPKLLLAPSPQLVQVKEEPVECDDQYDPPPLVDSASPMSEITQSAANSTSNLDVDVGTRHKGTALLHQQSSKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJW2</accession>
    <name>A0AAD8YJW2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Inositol 2-dehydrogenase</fullName>
            <ecNumber evidence="6">1.1.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_001902</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfo/Idh/MocA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.18" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJW2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050112">
        <property type="term" value="F:inositol 2-dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055170">
        <property type="entry name" value="GFO_IDH_MocA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030827">
        <property type="entry name" value="Myo_inos_IolG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04380">
        <property type="entry name" value="myo_inos_iolG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840:SF3">
        <property type="entry name" value="BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G10240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22725">
        <property type="entry name" value="GFO_IDH_MocA_C3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042236898" evidence="3">
        <location>
            <begin position="20"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="4">
        <location>
            <begin position="45"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="GFO/IDH/MocA-like oxidoreductase" evidence="5">
        <location>
            <begin position="172"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF22725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1747939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="439" mass="47253" checksum="F5E6D6F5A549E64B" modified="2024-05-29" version="1">MVRLGSALIAIFAVGSASAFAPASQHAVRSTHVLQMTTTEAKNPVKVGVIGCGRIGIVHLGAINKAPGVVPIVVSNPTVSKAEDAAKKFGVAKFTGDAMDVITDPDVDAVWICSPSQFHADQIKACAANGKHVFCEKPIATDLAETVEAINACNEAGVKLMIGLQRRFDPNFLRVRRAIEEKEVGDTIIIKTCSRDPSPPPYEYVKGGGGIFNDMAVHDLDMTRFLAGDDPIEILAVGSCHIDKSIEDLPGSEAFDTASCIVRYPNGVSAMVDVCRQSSYGYDQRAEVLGTSGMIATDNVYPNTAKIYKNNYTGNADMPFDFFLSRYFEAYVTETEAFCESLVNDSAVPCTGIDGLIALVMSLAADKSAAEGRWVKFSEIIEQVYCVNPTECSLIANDAMFPEGFKPVGDIKSLNEIVVPDVDQKKEEGFADKFKKIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKH2</accession>
    <name>A0AAD8YKH2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKH2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="15"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="388" mass="44271" checksum="EC407F2893D533EA" modified="2024-05-29" version="1">MSSPGPSKKIRSQPPDVIVAVGSGESMQEFHCYRVILSFASDYFDTMLSASMIENETGRIEFTNKDPLMWKKFYSFIDPDKLSVAETHATIDVTTAITFVPWFHEFQMTSFLKKCDVVLAERVEKIRAYEHEFLSFNDCDVDNGGLQEVIELLKLSCTYDLDKSKDKTEEYICSLLETIQNTSDLFDVHRIKSLHSLFAPVDIEQCTVFYEDGEEEIVKEIIPAGKSKRICNAFLNMLVSSDKPEFIYDLVSHLSLETINNAEVFPLLLHSYVLRAASVATTLSYKRKLADRDESLGAAKCVINDLLLKTPGTSEQYNELFQSIEGQIDTQTSQGWECLFQKGVLTPTRVKQQCRENMRRLNHATSVSGWRSPTVDDWRVRSRNQRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKV2</accession>
    <name>A0AAD8YKV2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_000370</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKV2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044174">
        <property type="entry name" value="BC10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003406">
        <property type="entry name" value="Glyco_trans_14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31042">
        <property type="entry name" value="CORE-2/I-BRANCHING BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31042:SF150">
        <property type="entry name" value="OS06G0661900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02485">
        <property type="entry name" value="Branch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1748431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="405" mass="45346" checksum="2C143CA295307867" modified="2024-05-29" version="1" fragment="single">PPPMDVAIRETTIIMQAINNKIAVVTWGRGGGRGYGRGGRWRNDDREQNSSSGQSTPLAELVTNVKSSYEASQTNAAINDAKTTKGDKRRHIALLFLTIDDLPHEHVWKEWLKSCSSNNKIDESTTKSSEEDNLSSSMMRLQWAMIDLMEEALRIGSTGESTNFAKYLSTPGDDELLNNSVSTEGTKSTGQDIPPVDRFIFVSESCLPVTTMEETEMALFGPKNASDSSASLYDKSWVNARSTPNNGYSRQLQWDAIRADNIPPNYIWKADQWMVLTRRDAEAVATLPSQHLNGRQLWPAFRKCRARRAQVDDFSKGESCAGRIRRRRITYCDWSQSAKNPASFTSQDWMDVVLKARREGCLFARKFVLLSSLRDGEKKNAESANNDGVVSVDDWTTVVVKKQVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLA0</accession>
    <name>A0AAD8YLA0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000643</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLA0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042294391" evidence="1">
        <location>
            <begin position="24"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="373" mass="41131" checksum="81E0CC749A9CAE1C" modified="2024-05-29" version="1">MNAPSWMALLLLVVATLLSNGMAFVGSPNNLIPYKQSPLLSAHQDESSSDGQVDRRSFLSVPLSSVILAGLPSGANAAKGAAEYDLEYYMRDLFMGNKKEGNLPVSNAPPAAPPRTLREPLLPLLLDDELKSSIPIQELARVTAIPIGALAEQVIAFRSKVAPAFQASHPWQKESVTDEYYFDLTCYALWKVASATIQDYAVRDKFVRSIGSRLLNEMVQREFLSKQSITLLNKNDNKLTDLIPCVIEVLDKFQSTAYCSSYRLGDKNDEERSGLKVFDELDDEEISSPNGAGSVNCLVSIFDPASLGGSLQITGEGSRFSPDFVGPTLAALFERVGAKVDFESYFVDPVYRPNPKDFFPNERFYQFTIARKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YM08</accession>
    <name>A0AAD8YM08_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">RING finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_001033</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YM08"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20354">
        <property type="entry name" value="Rcat_RBR_RNF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047548">
        <property type="entry name" value="Rcat_RBR_RNF14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22191">
        <property type="entry name" value="IBR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="63"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="266"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1749094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="462" mass="51081" checksum="91C8EF80AD045990" modified="2024-05-29" version="1" fragment="single">MEDSSDSNNLIVSSGGDDGGMEADQSEQLSDDSGGLHRKDPDPTVDDGDEEMSEPGDEVEEHYSYTCPICLCELAVIRNEGSDSEETNETGDPIFTLSACQHKYCLPCLHEYVKSKLVEGNLEISCCHFRPTATDEKEVDICNIAIARCDIKRLIHMDYFRRNYVSDWISDKKGKSTAQDANKAASNELWAKFKKLEFDRLHGKDAVRRCPTCDEAALFDIDAMKRHQTEFESIPTESATSNSAPAGASSNIISGFDRFFRRIRQTQDSNNTATTTTAAADNTSNNAEGNPADEEDEEQPTVLEPKGDLHSEEIVDVQIAEKISLVKSKSPVITCGSCSTEFCYFHSNAHQGQSCLAYHAATSEADRTNAEFATRVLRVKPCPNCGISVSKEGGCNQMKCSSCDTHFCWLCSAIIDDGPFPDHFRWWNINGCPNMQLDESTEPRRCTLVGARVLSVLQLLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMU2</accession>
    <name>A0AAD8YMU2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SEC14 family lipid-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000832</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMU2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="463"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="587"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1090"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="466"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1113"/>
            <end position="1124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1216" mass="136001" checksum="AE5BDE1E0D7A3DED" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YNM4</accession>
    <name>A0AAD8YNM4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000614</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YNM4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="144" mass="16316" checksum="CC844B003FDBDEC2" modified="2024-05-29" version="1">MIHHSSQMIGAAAAFRPAQEASEAYLQEKSHQTWRRVKIKILTIMRFGGSLRAKKNGGPQASSGDDKRMERGDRPLQKCMSYQFECVKTLRRQLSKPRTIWKPKLIVGSLRCMEVTQVFLLLSLGHKLYGALLVSSLPTPSFRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YNU9</accession>
    <name>A0AAD8YNU9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dihydroorotase</fullName>
            <ecNumber evidence="3">3.5.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_000764</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.3" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YNU9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004151">
        <property type="term" value="F:dihydroorotase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004721">
        <property type="entry name" value="DHOdimr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002195">
        <property type="entry name" value="Dihydroorotase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43137">
        <property type="entry name" value="DIHYDROOROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43137:SF1">
        <property type="entry name" value="DIHYDROOROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00483">
        <property type="entry name" value="DIHYDROOROTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="8">
        <location>
            <begin position="167"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1748825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="296" mass="32839" checksum="9B26507B48D1EA4E" modified="2024-05-29" version="1">MASQATAPEGTKLTITLPDDFHHHFRDGPSTANVLEHATQQFGRCIAMPNLRPPVTTTEMALEYRQRILSSLPKELPHGSFEPLMTLISPIILLRMRSKRHLQLDTSRHEIGMVLCIHSEVSTPGIDIFDREPVFIEEIIKPLASITCHHLLYNRNALLVGGIKPHFYCLPILKRETHREALLGAATSGSNKFFLGTDSAPHAVEVKEAACGCAGAYTAHCAVQLYAEAFDSMGALDKLEAFCSFHGADHYQLSRNTQKITLEKKSWIVPKRYSFGISQLVPIRAGESVAWSIVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPK9</accession>
    <name>A0AAD8YPK9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine sulfotransferase</fullName>
            <ecNumber evidence="2">2.8.2.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_001001</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-tyrosyl-[protein] + 3'-phosphoadenylyl sulfate = O-sulfo-L-tyrosine-[protein] + adenosine 3',5'-bisphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16801"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:11688"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:65286"/>
            <dbReference type="EC" id="2.8.2.20"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein sulfotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.2.20" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPK9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008476">
        <property type="term" value="F:protein-tyrosine sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026634">
        <property type="entry name" value="TPST-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12788:SF10">
        <property type="entry name" value="PROTEIN-TYROSINE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12788">
        <property type="entry name" value="PROTEIN-TYROSINE SULFOTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13469">
        <property type="entry name" value="Sulfotransfer_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="600"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="635"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="672"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="834"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1006"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1138"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="600"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="646"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="672"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="844"/>
            <end position="854"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1749062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1276" mass="142078" checksum="ED60A718B0F20F5E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3U5</accession>
    <name>A0AAD9D3U5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3U5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="165" mass="17301" checksum="52B294A8481C793C" modified="2024-05-29" version="1">MLQLGSSLTSTANDQRDDGPTSSHPGYSLGGDGRDAPLHGDASAGSLRSIVKTANATLQKSCSTIGSSINQNIQQSSTVLSECVGNKISTLRSTTLSMNRNKDDQGIFASQSGTSWGSVKENVSTVSTFTASKVAQVAQHARSGLVGHRSSKEEVSFNYQLMSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3Y7</accession>
    <name>A0AAD9D3Y7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016519</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000057">
        <property type="protein sequence ID" value="KAK1732807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3Y7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="414"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="639"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="639"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="662"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="701"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="718"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="777"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="794"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="839"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="868"/>
            <end position="906"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="926" mass="95685" checksum="569D1EC9B3534E59" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D464</accession>
    <name>A0AAD9D464_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_016033</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000051">
        <property type="protein sequence ID" value="KAK1733316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D464"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="3">
        <location>
            <begin position="210"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1733316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="352" mass="39501" checksum="D7876318B9C123E5" modified="2024-05-29" version="1" fragment="single">MRDDVTAATSFHDEGMRRRRVAGGNDQQHDPPGTPRKTTTNNTSNSSSGFSTVAKPAETVKKDKNESTRKPRGICAQSCGSGTVGGSVVLIFGLCVAYYVIFQPNNNNANPLSVLATNFSSMFPLKKATDTPLGDGPVPRPKDWHLWGYFNFKENFNCSGYLKDRTKPLPTMEYWETMLEAYNQVVDPTYKFDPDIPPTQGYRLNEDGAPPYYAKLSPGKGRGLFASRDIQKGEIVHNGTKSDVVFPNETSWKRFMFAMPRKMACDNAEWSFTQQFEKDGRMRIVSSLNIAILMNEGNHRNEVNVEPKDEKGEASEYSTLFRAIKDIKKDEEILMDYANYDTDYEAAGLAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4F8</accession>
    <name>A0AAD9D4F8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_016726</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000063">
        <property type="protein sequence ID" value="KAK1732585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4F8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015217">
        <property type="term" value="F:ADP transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080122">
        <property type="term" value="F:AMP transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005347">
        <property type="term" value="F:ATP transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015228">
        <property type="term" value="F:coenzyme A transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015230">
        <property type="term" value="F:FAD transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044610">
        <property type="term" value="F:FMN transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051724">
        <property type="term" value="F:NAD transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052217">
        <property type="entry name" value="Mito/Peroxisomal_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45939:SF5">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PMP34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45939">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PMP34-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="28"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="182"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="69"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="180"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="317"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1732585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="426" mass="48108" checksum="9F8575FBD9547A14" modified="2024-05-29" version="1">MSSPSSKTAAGDNGGSSSIWLSIRRNQILRHVLIASIACSLYYLKIYHTNDLAKKAEQQQQQQHQSNNNNNVIHALSGSLGSALSITIFYPLETVRTRLQVGDPNVTPSRWSFSLVYNIYQQEGLKGLYRGWWSLLVALMSLNFCYFYCFHSLRLWLLTFQNDDDTSTYVQLLLYKLNGHKMIVDLIAGYLSGCVAVIVTGPLWLVNTRLKLQGVSSVDKGGNDSKNCQYDGMFHGLYTIYKQEGLSTLWKGTFTSIILSLNPAIQLAAYEMLKRHHLIVRNGSRVVWWIVSTIIYHARGSTGYSQENDAVVNSTDGSAIEHFINALLSKFVATLITYPIQLIQTRQRWSKTQDNNTHKTKRKRWVGAATIHDLTEIIQQQGLLGLYRGLESKLMQTCLNSALMFVAYEELVELLTKLLRHDQGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4J6</accession>
    <name>A0AAD9D4J6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016552</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000058">
        <property type="protein sequence ID" value="KAK1732749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4J6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="209"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="423"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="561" mass="59770" checksum="9E343D19E9DA63D7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4V3</accession>
    <name>A0AAD9D4V3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Multidrug resistance-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_015129</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4V3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF456">
        <property type="entry name" value="MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN LETHAL(2)03659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="34"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="129"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="1"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="247"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1734126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="483" mass="53245" checksum="936AC3A82F9E131A" modified="2024-05-29" version="1">MGLTSGNVTNLVATDTQKLFEVMHDGHQIWSCPLAIVVVVVLLLLVVGPPCLVGAAILIGLVPLSKRVAHWIVRIRKQRVAVADERIEIVSAMLKDIKITKLMNYEDEFERRVQDARRREMALVRKEQFVWGLTLVIRVFTPVLASSATFVTYVLVSQDNIMTASVVFTLTMLFNMLKFPINQAGQLLSKAALGVQAIHRISRFMGRESKEHGISERQQISAEGDDKEDVVLEVKDGSFHLGGGASIPSADRVDSEVTNATASFTLSGINFRLNRGEVLAVVGPVASGKSTLIQGLLGDVQSSDETSIAMASGSNVSYAAQTPFILSTTVRENITFGSPFDRDRYDRVLDACCLRPDLKQWPAGDLTEIGERGVTMSGGQKQRVSVARAVYANVDVVLFDDILSALDAGTSQKLFDNLFDNVHDTTSLLHNCGSSLSLIHDIFFKEWTRYWFLTRESQSFVGAGPIFNYSSQIMPDIRRLSDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4Y2</accession>
    <name>A0AAD9D4Y2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1733962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4Y2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="173" mass="19341" checksum="4D30206EDB8B59A3" modified="2024-05-29" version="1">MTSSSSSKHWKVAVAAPSPSQSIPIAGISRSNFELEDLAHAELLADYRDGQMYERIMKGILRRSDGTGTYHPKTLTSLNNIIHTKMQDYESIFENRRSRHSDEDWFIGDESEPIHSHPVREPTRHKERYPSLSSSESETLDGSISSLSCSSTTSISSYSGSEAEDNGIFELEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D552</accession>
    <name>A0AAD9D552_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">REJ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016035</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000051">
        <property type="protein sequence ID" value="KAK1733318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D552"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042083933" description="REJ domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="105" mass="10523" checksum="7A732B3CAFBEC3B6" modified="2024-05-29" version="1">MKLLHFLLITLVAGAAAKGSTSGLRGLASASKSGKRSSPTKSSKSTSTKSTKSSTSSSSSSTGCSHSSSSSSSSSCYSSKSNKSSPYTYSSTRSSTRSSKATSPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5R2</accession>
    <name>A0AAD9D5R2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_015252</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1733994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5R2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000041">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase ERECTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46662">
        <property type="entry name" value="DI-GLUCOSE BINDING PROTEIN WITH LEUCINE-RICH REPEAT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46662:SF104">
        <property type="entry name" value="GPI-ANCHORED ADHESIN-LIKE PROTEIN PGA55-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="5">
        <location>
            <begin position="623"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="240"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="61"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="91"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1733994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="858" mass="92920" checksum="4C25884D399E2150" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6P3</accession>
    <name>A0AAD9D6P3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Type 2 periplasmic-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_013374</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000031">
        <property type="protein sequence ID" value="KAK1735927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6P3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35936">
        <property type="entry name" value="MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041957673" evidence="3">
        <location>
            <begin position="20"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Solute-binding protein family 3/N-terminal" evidence="4">
        <location>
            <begin position="27"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="289"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1735927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="335" mass="37065" checksum="03AA9A9A64E8BEBC" modified="2024-05-29" version="1">MRIKAALLSVSWFAHAASSSSVGDDITLHAGIMSLPPYAVLTNKTWSGYMFDLANLLMDNAETNHNVSLNIIMNASDPYYMLNVSPSNYSYNGALKLLSPECPFDDCLDMIFADFYDTPERRELVSFTPPYQISYNTYFKRKNNTINTVKEVNENGGSGCLIAGTATYTAVSPYFDTVLDCEDAYDCYDKLMLDKCDLFAGDVLIGKYQIKESYPDDLTYTGEVINKLAYKLALPMKKSLPQSTLQLMNDLMNEATTSGELGNIEKKYFGTSSDIAALEEMYFGGKDDVITNEEDDSGTDTSISATEATDESDSSTVSTRKSFTLVMGVLLLFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D806</accession>
    <name>A0AAD9D806_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000024">
        <property type="protein sequence ID" value="KAK1737666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D806"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="1">
        <location>
            <begin position="248"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="453" mass="48503" checksum="234E3F6DC2ED4E7F" modified="2024-05-29" version="1">MVHLAALCNRSSRLVIVSQRPRKLLTTKRSFFSFFGSNDNHSSSTRLTEEETAAQVKQQEEATRILLDGVYHRISIQHAHPLGPWQAILAAVQDHYNSWVDVQDAIKLKKEDNAAEEIARTHEELGIASTILPAAVAAAAPFRVLDLASGPRGEPGTTIAHALPLAAVHCTDSCSVAVAAIPVHILVDEAISNTAAVTDVGIVGLSKKNSILSAIAGDDATIQAVVPLSSSNLLPLIPPPPKNLTKSIADLTDLSSYRSNSFDAIICCYGYNLSSNVPHALAEAYRVLVPGGVLIIATWERSAMLAIGRDVEAYVRGGGRDPYSTMDDDESFLPPRIVPVNKIELSGAGELEALLIASGFDQPQAVLAKSLVYPIDLGNNSDDQFAMGTILVRDELESLGALSRPPATDGGNGAWGNLAEEAFWMNIQKYADVVEGNLLLRDNTYKLTVSAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D812</accession>
    <name>A0AAD9D812_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamyl-tRNA(Gln) amidotransferase subunit A</fullName>
            <ecNumber evidence="2">6.3.5.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011728</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.7" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D812"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895:SF67">
        <property type="entry name" value="AMIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="1">
        <location>
            <begin position="219"/>
            <end position="640"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="680" mass="75933" checksum="AA4B7E06B27371A2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8C1</accession>
    <name>A0AAD9D8C1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Plastid-lipid-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8C1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="714"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="719"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="842" mass="90990" checksum="D26B295ABC295F8C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8R5</accession>
    <name>A0AAD9D8R5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012455</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1737010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8R5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="233"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="377" mass="42828" checksum="C375C18639B9899D" modified="2024-05-29" version="1">MIRRLLHETRRRCLRGCCDWRRRHNTTPLTSLAYVQIIAAKFLLEVLGAAGAVWGNCDMFFLRTTEEGNRISRIYATIIGCIFLIRYYWHAKHRFQTGGDFMIPKEHHRRTHRLEFAQIHASKFILQVLGGGGAVWGSSEVLTLRNAATTSEWRIASIVVGCIFLIRWMFQMSAYCLCFSGRWVDPTTFLLTALRFYDAFIVTFILEVLGAAGAVWGASEIATLRNPETNDRWRIIASVVGIIFLFRWIVHLRAFIQSENTSPITVKNDDEVKDLDAEIGDLVLNESTSTEVSADTNNEEYPILNEAISVSDQTLPSMLRQPSGILDRQTSVERPTTPILDRQPSGVLHRQISERNSPPPSPKHFFPASPPLRQLDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D962</accession>
    <name>A0AAD9D962_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ornithine decarboxylase</fullName>
            <ecNumber evidence="6">4.1.1.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_011731</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Orn/Lys/Arg decarboxylase class-II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.17" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D962"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004586">
        <property type="term" value="F:ornithine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033387">
        <property type="term" value="P:putrescine biosynthetic process from arginine, via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002433">
        <property type="entry name" value="Orn_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11482">
        <property type="entry name" value="ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11482:SF6">
        <property type="entry name" value="ORNITHINE DECARBOXYLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn/DAP/Arg decarboxylase 2 N-terminal" evidence="5">
        <location>
            <begin position="44"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1737445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="380" mass="42322" checksum="83B6A7566485CB58" modified="2024-05-29" version="1">MKFSSDMRYTSAHHRYYYIRITSNGQEHNDDTSSERYGVVDINDVSSHIELFKKQVPYVNPSYMIHTHTKNADAPLITALHESNCIFNLNSIVDVRNVVGILGHTHSCCFAASVKSQFHIKEAVNLGINRMTVSYPAEVLRISAVSKTIELVLQISSSSVNRIVKKDTAGAQKSSWTKILQTANSKGMKIVGVAIGRSTSSEYANETEIIEEAFSNALEACDLASQYGHSVSFVDLGCLVSDFQRTSPSHDRCSTILEEVDDEDDYSNDEQYQCAWESDDRAGEDAFLTTLFEMYLPHSLGLQVYAQHAQYLVPDHAKIIKWWSTPKARRPTPSLHSFLAGGCSSNTKSMNRNAYRSRKQQTITSSSCNILKNPPAAAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9A5</accession>
    <name>A0AAD9D9A5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">protein xylosyltransferase</fullName>
            <ecNumber evidence="6">2.4.2.26</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Peptide O-xylosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">QTG54_010317</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>UDP-alpha-D-xylose + L-seryl-[protein] = 3-O-(beta-D-xylosyl)-L-seryl-[protein] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50192"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:12567"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57632"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:132085"/>
            <dbReference type="EC" id="2.4.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan metabolism; chondroitin sulfate biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Glycan metabolism; heparan sulfate biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glycosyltransferase 14 family. XylT subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.26" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9A5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030158">
        <property type="term" value="F:protein xylosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030166">
        <property type="term" value="P:proteoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003406">
        <property type="entry name" value="Glyco_trans_14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043538">
        <property type="entry name" value="XYLT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46025">
        <property type="entry name" value="XYLOSYLTRANSFERASE OXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46025:SF3">
        <property type="entry name" value="XYLOSYLTRANSFERASE OXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02485">
        <property type="entry name" value="Branch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="17" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="14" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="20" id="KW-0732">Signal</keyword>
    <keyword evidence="12" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="20">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041952427" description="protein xylosyltransferase" evidence="20">
        <location>
            <begin position="38"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00042865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00047847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAK1739001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="521" mass="58989" checksum="7308CE0C315BDAD5" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9Y4</accession>
    <name>A0AAD9D9Y4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">D-xylose 1-dehydrogenase (NADP(+), D-xylono-1,5-lactone-forming)</fullName>
            <ecNumber evidence="3">1.1.1.179</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">D-xylose-NADP dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_011384</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-xylose + NADP(+) = D-xylono-1,5-lactone + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22000"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15867"/>
            <dbReference type="ChEBI" id="CHEBI:53455"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.179"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfo/Idh/MocA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.179" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9Y4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047837">
        <property type="term" value="F:D-xylose 1-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050984">
        <property type="entry name" value="Gfo/Idh/MocA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055170">
        <property type="entry name" value="GFO_IDH_MocA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22604">
        <property type="entry name" value="OXIDOREDUCTASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22604:SF105">
        <property type="entry name" value="TRANS-1,2-DIHYDROBENZENE-1,2-DIOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22725">
        <property type="entry name" value="GFO_IDH_MocA_C3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="24"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="GFO/IDH/MocA-like oxidoreductase" evidence="7">
        <location>
            <begin position="152"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00042988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF22725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1738090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="376" mass="41619" checksum="8330B1AB67438576" modified="2024-05-29" version="1">MLHYKAAAPMVTRRLFSSQQLNPIKWGILSAGRIASDYAKAITITDGAVASAVAARCPTKAKEFATLHGIDKSYGCYHDVINSPEVDVVYIATTADHHFEWAKQSLLAGKPTVVEKPMTLRLADTKELIDLARQNNTFLMEGMWTRCFPAMHKLRQIIAAGELGRIVYCQGDFGWKFPANNLDDRIWYKESGGVTLDIGMYCAQIGRVAFPSASLKDVRATGTVKNGVDYSVMATVRYQQEDEAEDGLLQFAVTGAANTEERLVIQGTKGRAILDAPFHVPERLRVSKDQGRGETEEVVYDYPLPNDPFEVWNNPGSIGFYHQINEVGKAVKEGRNECDSYTWNDSLEVALIVDEIVDQVRGEGNDVSSSGACRQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAK9</accession>
    <name>A0AAD9DAK9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008506</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAK9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="243"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="398"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="624" mass="69692" checksum="03C444BE3665A610" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAX3</accession>
    <name>A0AAD9DAX3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008881</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAX3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00136">
        <property type="entry name" value="PDZ_canonical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="84"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="498"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="554" mass="59252" checksum="BF884E838A4BA797" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DB20</accession>
    <name>A0AAD9DB20_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CLASP N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008897</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DB20"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024395">
        <property type="entry name" value="CLASP_N_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12348">
        <property type="entry name" value="CLASP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CLASP N-terminal" evidence="2">
        <location>
            <begin position="209"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="433"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="582"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="723"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="437"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="461"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="484"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="522"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="755" mass="82764" checksum="7AB346FD0584DCC0" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBS9</accession>
    <name>A0AAD9DBS9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD-binding domain-containing protein</fullName>
            <ecNumber evidence="8">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_008030</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBS9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041906532" evidence="6">
        <location>
            <begin position="30"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="7">
        <location>
            <begin position="145"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="7">
        <location>
            <begin position="521"/>
            <end position="726"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1741552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="903" mass="97619" checksum="AF1D8C9E241C3A19" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DC52</accession>
    <name>A0AAD9DC52_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_009260</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DC52"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1740310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="475" mass="51770" checksum="074DDB45EE16B4F0" modified="2024-05-29" version="1" fragment="single">VKEALLPPACSLHFAAPATATYLPPTSYGNGLVSGLFIIMQGCVEGSSATGSKHSSNKSQDDKPTNQRQPEQSNPTVAHKIINITAESLSQPQEGAVSIVDPWVPRIAHNDGYLQQGLDFSIGPRNGGGSADTQDDALKDTIISPFVGDIGAKRLGSALSNNNLLLYLNLSNNRIGIEGGIELARALYNDGNQSRTALQRLNLSSNCISDDGAAAFKEALMYNDTLEELCISDNEMGINGVVALLEGLQHNDAIKIMILCNNLHSLVDKEMERLIENTCDVLRKNSTGLNGGRLEVLEMGNGANSDLFDDGLSDIHSRNLIQAMSYFDAQNMKQLVNHRFMRLTLPASRIMHGHTNNKMARLLGFNSFYRPIIELYDIIRTNNMEKDAIVSHKAIPTHLQRDAETGALIGLLPSTSSDHHSCGISYKLLPRAMAFATTKCTLETFFNLIRYRPDMFFSVDSSRVVGCSPNGCCIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCI9</accession>
    <name>A0AAD9DCI9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA/RNA-binding protein KIN17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_008840</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KIN17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCI9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.140:FF:000092">
        <property type="entry name" value="DNA/RNA-binding protein KIN17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.2030:FF:000001">
        <property type="entry name" value="DNA/RNA-binding protein KIN17, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2030">
        <property type="entry name" value="DNA/RNA-binding protein Kin17, conserved domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056767">
        <property type="entry name" value="C2H2-Znf_KIN17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019447">
        <property type="entry name" value="DNA/RNA-bd_Kin17_WH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037321">
        <property type="entry name" value="KIN17-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038254">
        <property type="entry name" value="KIN17_WH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041330">
        <property type="entry name" value="KN17_SH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041995">
        <property type="entry name" value="KOW_KIN17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12805:SF0">
        <property type="entry name" value="DNA_RNA-BINDING PROTEIN KIN17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12805">
        <property type="entry name" value="KIN17 KIN, ANTIGENIC DETERMINANT OF RECA PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25095">
        <property type="entry name" value="C2H2-zf_KIN17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18131">
        <property type="entry name" value="KN17_SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25092">
        <property type="entry name" value="SH3_KIN17_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10357">
        <property type="entry name" value="WH_KIN17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01253">
        <property type="entry name" value="Kin17_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="215"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="238"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="278"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1740745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="446" mass="51447" checksum="C6A9BB6BFC2E9495" modified="2024-05-29" version="1">MPKAEKGSAKDVANRMKAKGLQKLKFYCQMCSKQCRDENGFKCHLTSDSHLRNMKLFRDNASGIMDDFSSDFENVFVETLRRRHGTQRMNANNVYQEVIMDKNHVHMNSTKWASLSDFVQYLGKKGKCVVEETERGWYVTYIERDPALLARQEALKKKAVADQREEQLAAERREVLRMEAAKALDRAGGVVERVASEIGSREDGDQKMIEMKLGGTMSTASQPKKKRKGNTGAKLSLVEEDDDDELEHEESKKKTPEESLAMQINDRYNKQKMKAEPNNPSRATPSSNSKRQHEPPTNARAENTEKKKHKSDKKYKNDDNKDQKKDYWLYRDIIVRIINKKLSNGQYYKRKAIVDKVIDKYEARVEVLESSRKAKDGGDILRLDQDDLETVIPKELGEKVRILAGKHRGKKAKVLRLTKEDYRAELRLTDDDRVVTLDYEDFSMLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DD26</accession>
    <name>A0AAD9DD26_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_007791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DD26"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1741313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="341" mass="38601" checksum="84C27F52392894C9" modified="2024-05-29" version="1">MSGRASEHRKPLSELIRSFQTFDYTTASSSLIPALRLTCSLADEILKAKEETSRSPTPRFDWTDSIVVYSQSNRSNQIDFDIDIENALDNILTDDDDDEIRVEILPALFDNTENDESQMDGMLYSLGIVFYEIFSGGERPAELEQKQIVQTTHGGETGAEELSNEEDFNPFLQGETIHHDGELSMYQNMLSDYNLSDDDSRSSYDMVFQGDGDGPRKRRTQNENYNMCSVSVEPLKERGVPMSLCDLVANMLDCANGTLRKDETYQDMSEVRDDLQLMLDKPSIYLHDQDMGRLSTTGLQIGDTLFGRNAELSSIKEAYQRTVAGDNELHARAGIEFYYSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDC6</accession>
    <name>A0AAD9DDC6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transmembrane amino acid transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_007203</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDC6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF652">
        <property type="entry name" value="TRANSMEMBRANE AMINO ACID TRANSPORTER FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041982590" evidence="6">
        <location>
            <begin position="21"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="305"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="390"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="414"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="456"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="7">
        <location>
            <begin position="68"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1741630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="479" mass="50074" checksum="419E610EDD1863DF" modified="2024-05-29" version="1">MKFTSALVLLLSISAPITDARRATNSLASIPRGGATKQSVAFHKDARVWEGDASSTAKEVRGGDGGGTSTMTSHLFNMVKAIVGVGVLSLPAGIAAFGDAPSASIPAAILIASIGSIAAYNFSLLGRLCAMTGATSYKSAWEETVGASTAWIPGSSCVIKTFFAVLAYSMVLGDTFSALFETFGFNVSREKALIGLTVTVLMPLCKLKDLSSLAPFSLVGIAGMLYTALAMAVRFFDGSYAEGGKLAADVAESLRPALGTKGASAVFSSNAFILICMLSTAYMAHFNAPKFYLELENNTIARWNTCVATSFSISILFFIGIAAMGFSTFGGASNGLILNNYSTKDSLMGFSRVAVAFALVFTYPLAFVGCRDGTLEMMQVPKEERTDAKLNNLTYIILASVTAVAMKITDLSFIMSFGGATLGNALIYVYPAIMFRSAVKNLGDDATAAQKLEVKLAMAFAALGIGMGAIGTKMALGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDD5</accession>
    <name>A0AAD9DDD5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Heterotrimeric G protein alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_007233</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDD5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000692">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF302">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-5 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0807">Transducer</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="53"/>
            <end position="58"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="206"/>
            <end position="207"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="231"/>
            <end position="237"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="256"/>
            <end position="260"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="325"/>
            <end position="328"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="384"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1741660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="433" mass="49027" checksum="0E5BE7A4BF45E8E0" modified="2024-05-29" version="1">MGCCCGASSPDEVATPSPSVGASVESRTIDNQLKRMRHEEEGKIKMLLLGAGESGKSTILKQMRLLYGTELSDDDLRMYGVVVRSNIVVATRKLCGHLRNLGLEEELDRESRKDLEDGDHRAMTCRQAYDELMAYLVEFTVPPKEMGASNVEGGGTDWVGQSPRAGMSANNDAKHFLAHHESIRILCQSKTMKQVWAKRAAVNVVDSHKEFLNDIPRIASPDYKPTTQDVLIARVRTTQVVKERYRIDGIDFEMYDVGGQRSQRRKWIDCFDQVTAVIFVVALSEYDQTLAEDKRINRMVEALTLFRHVSNHRAFENSSIVLLMNKMDIFREKIMYSDIAAQREFSDYAGPTKDFNHGVAYFVQKFKNCLVDELDDSFIHVTCATDTNNMEVVLDSARAIIMTDNLKRRRDSLKYTNRGTLKKSQRDLAAQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DE26</accession>
    <name>A0AAD9DE26_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DE26"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="150" mass="16418" checksum="7D4F42ADDB883953" modified="2024-05-29" version="1">MTSSNDRTKIAITVPTKKHDGGSDSESAASSATASKPRVDAFAKYSSNLIRMKELLLLGDDDDDLDYLASLNEALRHASIGDHAARNRNNHAGDASKRRKGNNSQPVKQQGFLERKTRVSFELHPSLLLHDLIDLNASAYIPDDEDESEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEH1</accession>
    <name>A0AAD9DEH1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Heat shock protein 90 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_003992</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEH1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070013">
        <property type="term" value="C:intracellular organelle lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16927">
        <property type="entry name" value="HATPase_Hsp90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.790:FF:000004">
        <property type="entry name" value="Heat shock protein 75 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.80:FF:000004">
        <property type="entry name" value="Heat shock protein 75 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11260:FF:000004">
        <property type="entry name" value="Heat shock protein 75 mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="entry name" value="Heat shock protein 90, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00505">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019805">
        <property type="entry name" value="Heat_shock_protein_90_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003555">
        <property type="entry name" value="PRK05218.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110942">
        <property type="entry name" value="HSP90 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00298">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0346">Stress response</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="620"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="620"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="217"/>
            <end position="218"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="464"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR002583-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1744701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="787" mass="88307" checksum="0877001A96E64A76" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEH7</accession>
    <name>A0AAD9DEH7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Metallophosphoesterase family protein</fullName>
            <ecNumber evidence="4">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_004770</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEH7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="entry name" value="5'-Nucleotidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="5'-NUCLEOTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575:SF22">
        <property type="entry name" value="ADL392WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041968710" evidence="3">
        <location>
            <begin position="22"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="742"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="670"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="107"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="673"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="694"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="720"/>
            <end position="736"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1744237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="805" mass="87747" checksum="A403EF33267433E6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DER5</accession>
    <name>A0AAD9DER5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DER5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06587">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40280">
        <property type="entry name" value="BLR6907 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40280:SF1">
        <property type="entry name" value="VOC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="430"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="494" mass="55332" checksum="A9117A199E9AA6E1" modified="2024-05-29" version="1">MVATKLPCSLQSFPPNILLTLVIILLLGGGENYLPRAASFVLPSAPSKSPSAHPNKMLMSSTSQSSATEAVAPATLGPTALRTLVQNASIESQHCLDLNGIVWLEHLNLVVGDMGLALKFYVDFLGLSRDSNPKHVNMGQQQFHLAATDDPPQRITGSIGLTVPSLQKIKGRIERSKSDLQGTLFAIDKESDKVMTITCPWGNIFHLYDISLDDDHATESNTQSPHKMVNMHAEGAQPIARFYEDVMKCNQVMTKTIDDSGNECAIIGVGPGVHFAFVESSELTTESLDMQEGVHACIYISNFESTYHELKDRGLIWTNPRFTHLDSCDTWEEACSSRTLRFKDVLDVKTGEKVLELEHETRPMRHGQYLKIYHQWASVDTTSFGDDSNATMLVSPTSTDRHLSTPFFFLSEYVSSRVVNDAIASMWSLRKEPSEQSREEHRSTQDANTVARKRKRAQQSQEERRRHRSHTAPQQTRVSQQQTSLYNYLRSLQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFJ1</accession>
    <name>A0AAD9DFJ1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005355</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFJ1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1743758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="152" mass="16627" checksum="8C8B7E23CD259F25" modified="2024-05-29" version="1" fragment="single">GDTITENYLSDASLGTIAKSCPNLQYFAYKISSGYYYKEELDGLSGKGILALVSDCRRLEVLELENAKRVGRETFVEILQMLALARETSAVAKAVVSDDDGTFALVRLFLRGTHSSLQEIHFFSKIPLIAIKQGRIPLLLSVGIGIAQGLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFP1</accession>
    <name>A0AAD9DFP1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005012</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFP1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="130"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="17"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="226" mass="24783" checksum="2370D73A392B6A90" modified="2024-05-29" version="1">MAIKFNSRRKASKSVKQDVSAQYSQRLSGKQGVSNVSTNNRKAEPVSLYKEQRAETNSDEARDVHPMARLFDDASSVISGAMSEAASMANDVKMIIAADVDDVSALGEERSVAPQPEPDKIKVYGGPNDLARLIKDLGQQEKKMEKLGQEYINAEKDVRNTRKRIKALSEKLNLDSAINENEQEDDEGSLGESSIVETLSAAGGEFVRFSSRIEDAATKAIFPRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJX4</accession>
    <name>A0AAD9DJX4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000409</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJX4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="325" mass="38481" checksum="66C7D4DF611C82BE" modified="2024-05-29" version="1">MMAEDSYSILREAQLINNDLGRHSVKCNFSTRLSGRFYQNCSLERYTMRRSRLSEMQSKRRRLERELVLEKRRVTLLGERLVEMENAREFALDMIFAIQRGVLGLQALVRRRQAMKLLESMKQRVRMRDMIVLFCQSRYRGWRGRLRAASTREYVRQQLMNKCATTIQTSIRCHSQRKVYLVMLLERQILRDRSATSIQAVFRGHRMQRLYCEEMQRRQAAALAVQRAYRGMQGRRVAKRLREELARLRAEAEEKPKRIPLHMRRYSTYGASVNGSQSQQRRSSILTRRRGSIDLTKTSQSAFNSANSSMIQEWMPMKTTVLQQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DK26</accession>
    <name>A0AAD9DK26_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cyclic nucleotide-gated ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_001023</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DK26"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098855">
        <property type="term" value="C:HCN channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003254">
        <property type="term" value="P:regulation of membrane depolarization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035725">
        <property type="term" value="P:sodium ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.630">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051413">
        <property type="entry name" value="K/Na_HCN_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45689">
        <property type="entry name" value="I[[H]] CHANNEL, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45689:SF5">
        <property type="entry name" value="I[[H]] CHANNEL, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="3">
        <location>
            <begin position="282"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="455"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1749084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="482" mass="55297" checksum="F0AED424132510F6" modified="2024-05-29" version="1">MDVKLVRRNYLTGFFITDFCSSIPLDLILKTAGVDSVGGTVTGTKQSLKMLKTLRITKLLRLFRINRLFQYLKKVMLLIEETLNIRISDGFTKLMRLGVGALILAHWIGCFNFLLVRLHDFPSDSWVVYAGLVDKSPYVQWSWSFFKALAQMIMIGFETPPFTNVSCDALSDWCTIEYWVTLGCLYLGAIFYSLLISSISSILQTANQASRQFDENLLKVDDYMRSKKLPAAMREKVKDYFYLQFSNGKLHREEEILDFLSPVLRREIKQFTGRDICRKVPLLSTPTHRDFSEGISCVIEPTIVFANEVIMKEQTTGDEMFFILSGVVEIYVASKQIASYVAIGDGCYFGDVSVLLGVRRTASAKSKTQCMLYRIRKSDLVSLLHDHPAIESRMRNIAQSRRRRLAHYLNPDEIKLSAGDEVDSEDSRTDLFGLPSDDVLHEKDEEYNQERLQSGIRRRTFHHHSQNRRRNALPIKSINNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DKF8</accession>
    <name>A0AAD9DKF8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA helicase aquarius</fullName>
            <ecNumber evidence="7">3.6.4.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_000602</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17935">
        <property type="entry name" value="EEXXQc_AQR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002863">
        <property type="entry name" value="Pre-mRNA-splicing factor cwf11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048966">
        <property type="entry name" value="Aquarius_b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048967">
        <property type="entry name" value="Aquarius_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032174">
        <property type="entry name" value="Aquarius_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF5">
        <property type="entry name" value="RNA HELICASE AQUARIUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16399">
        <property type="entry name" value="Aquarius_N_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21143">
        <property type="entry name" value="Aquarius_N_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21144">
        <property type="entry name" value="Aquarius_N_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA helicase aquarius N-terminal" evidence="4">
        <location>
            <begin position="142"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="RNA helicase aquarius beta-barrel" evidence="5">
        <location>
            <begin position="566"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="domain" description="RNA helicase aquarius insertion" evidence="6">
        <location>
            <begin position="818"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="2">
        <location>
            <begin position="886"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="3">
        <location>
            <begin position="1202"/>
            <end position="1396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF21143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF21144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1748663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1467" mass="163426" checksum="9F4D5BF4001F4E84" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2PYF3</accession>
    <name>A0A7S2PYF3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Chlorophyll a-b binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_013019</name>
        <name evidence="10" type="ORF">SMAR0320_LOCUS20829</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated. Energy is transferred from the carotenoid and chlorophyll C (or B) to chlorophyll A and the photosynthetic reaction centers where it is used to synthesize ATP and reducing power.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fucoxanthin chlorophyll protein family.</text>
    </comment>
    <dbReference type="EMBL" id="HBGZ01029306">
        <property type="protein sequence ID" value="CAD9626518.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S2PYF3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030076">
        <property type="term" value="C:light-harvesting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="8" id="KW-0157">Chromophore</keyword>
    <keyword evidence="7" id="KW-0437">Light-harvesting polypeptide</keyword>
    <keyword evidence="5" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042409332" evidence="9">
        <location>
            <begin position="16"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CAD9626518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1736419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="194" mass="20889" checksum="0F993EED07DADB50" modified="2021-06-02" version="1">MKTAIIATLVGSAAAFAPSPVARVESSLSYAKELDSMAGVSNEVGGKVWDPCGLSDYVPADWARRAELSNGRSAMLATVGWFFPKIFGTFDSTDVTTTDPIDAILQSDPQWWVQFIVLCGVFESWKYNQEMSGKSFLGGAAPAVDYLKLWPEDAAKQEELKLKELKNARLAMIGIAGLVSNHLLPGSCPVPPGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQX4</accession>
    <name>A0AAD8XQX4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 16">NADH-ubiquinone oxidoreductase chain 5</fullName>
            <ecNumber evidence="2 16">7.1.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">QTG54_017088</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="mitochondrion" evidence="21"/>
    <reference evidence="21" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 16">
            <text>a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29091"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.1.1.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the complex I subunit 5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.2" evidence="2 16"/>
    <dbReference type="EMBL" id="JATAAI010000083">
        <property type="protein sequence ID" value="KAK1732047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQX4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015990">
        <property type="term" value="P:electron transport coupled proton transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010934">
        <property type="entry name" value="NADH_DH_su5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018393">
        <property type="entry name" value="NADHpl_OxRdtase_5_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003945">
        <property type="entry name" value="NU5C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001516">
        <property type="entry name" value="Proton_antipo_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01974">
        <property type="entry name" value="NDH_I_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005141">
        <property type="entry name" value="PRK06590.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42829">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42829:SF2">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06455">
        <property type="entry name" value="NADH5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00662">
        <property type="entry name" value="Proton_antipo_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01434">
        <property type="entry name" value="NADHDHGNASE5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01435">
        <property type="entry name" value="NPOXDRDTASE5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="14 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="13 16 21" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11 16" id="KW-0520">NAD</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="17" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="6 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 16" id="KW-0813">Transport</keyword>
    <keyword evidence="12 16" id="KW-0830">Ubiquinone</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042045209" description="NADH-ubiquinone oxidoreductase chain 5" evidence="17">
        <location>
            <begin position="17"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="76"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="209"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="253"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="311"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="382"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="421"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="464"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="519"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="619"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="644"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="domain" description="NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal" evidence="19">
        <location>
            <begin position="64"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="NADH:quinone oxidoreductase/Mrp antiporter transmembrane" evidence="18">
        <location>
            <begin position="130"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="NADH dehydrogenase subunit 5 C-terminal" evidence="20">
        <location>
            <begin position="513"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU003404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF06455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAK1732047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="669" mass="74997" checksum="DC669E37D679B52C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRD0</accession>
    <name>A0AAD8XRD0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Chlorophyll a-b binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_016895</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated. Energy is transferred from the carotenoid and chlorophyll C (or B) to chlorophyll A and the photosynthetic reaction centers where it is used to synthesize ATP and reducing power.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fucoxanthin chlorophyll protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000067">
        <property type="protein sequence ID" value="KAK1732414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRD0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030076">
        <property type="term" value="C:light-harvesting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="8" id="KW-0157">Chromophore</keyword>
    <keyword evidence="7" id="KW-0437">Light-harvesting polypeptide</keyword>
    <keyword evidence="5" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042076187" evidence="9">
        <location>
            <begin position="17"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1732414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="197" mass="21184" checksum="B510423309737CB2" modified="2024-05-29" version="1">MKTAFATLALAASASAFAPAPVNTKSATQLNDVWDSYIGGQDFKGGNFKFDPLGLSETYSPFVPFFREAELRHGRTAMLAVVGFIATDFVRIPGDAYSFDAIPKTVDAHNILLEGPMHQLLLFIGLFDAVITIPAIQATMKGERDAGDFGFGYQGPKDAAKMKDMEMKEILHGRLAMCAIGGIATQTVISGHGFPYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRS5</accession>
    <name>A0AAD8XRS5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_016810</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C85 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000065">
        <property type="protein sequence ID" value="KAK1732527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRS5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061578">
        <property type="term" value="F:K63-linked deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050704">
        <property type="entry name" value="Peptidase_C85-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419">
        <property type="entry name" value="OTU DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419:SF4">
        <property type="entry name" value="OTU DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02338">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="OTU" evidence="9">
        <location>
            <begin position="449"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="8">
        <location>
            <begin position="778"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="85"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="262"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="679"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="244"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="315"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="329"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="365"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="682"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="704"/>
            <end position="726"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1732527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="823" mass="88444" checksum="5370C4C7A3D2D8BB" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRZ3</accession>
    <name>A0AAD8XRZ3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MBD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016816</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000065">
        <property type="protein sequence ID" value="KAK1732533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRZ3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.890.10">
        <property type="entry name" value="Methyl-cpg-binding Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001739">
        <property type="entry name" value="Methyl_CpG_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01429">
        <property type="entry name" value="MBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MBD" evidence="2">
        <location>
            <begin position="244"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="633"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="701"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="859" mass="94201" checksum="0FC698E5C817F7D5" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XS54</accession>
    <name>A0AAD8XS54_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016879</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000066">
        <property type="protein sequence ID" value="KAK1732485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XS54"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="127" mass="14358" checksum="34B4036214D9A1A6" modified="2024-05-29" version="1">MVWNRIRDAISGPPTLEGPSQLPTYFPVEPAGCEKHAEKLFACLANEATTKARDMEKMGYGKSYYEDVEKERVAKLQQQPKKDDTTAATKIDDKADIDKSKLPSPNDNPLDECRLAIAYYKRCCDRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTG0</accession>
    <name>A0AAD8XTG0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000048">
        <property type="protein sequence ID" value="KAK1733539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTG0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="141" mass="16336" checksum="BCFFB7DC03659FD6" modified="2024-05-29" version="1">MLRCEPTKQPPTEAPAYNILDPLTQPPPECTFDKRLCRKFGVNFIGRCICEEIPVDKRNLEIIAEDCYLVSANKLKNKNKRIMLYWWYATNIYSLNGKGNRGKLPDCLEYAIKAKYPEKDSSDWTGYKDGSKPKKKKIQLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTI5</accession>
    <name>A0AAD8XTI5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nucleoside hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_016234</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IUNH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000054">
        <property type="protein sequence ID" value="KAK1733096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTI5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008477">
        <property type="term" value="F:purine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006152">
        <property type="term" value="P:purine nucleoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="entry name" value="Ribonucleoside hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023186">
        <property type="entry name" value="IUNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304">
        <property type="entry name" value="INOSINE-URIDINE PREFERRING NUCLEOSIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304:SF4">
        <property type="entry name" value="URIDINE NUCLEOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="Nucleoside hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="355"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="Inosine/uridine-preferring nucleoside hydrolase" evidence="5">
        <location>
            <begin position="10"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1733096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="381" mass="43103" checksum="A7D824FC3BCBC67C" modified="2024-05-29" version="1">MTMIKEPIPLWIDTDTSGLVWSGLDCDDDLAVLAALALHKRQIISLDGISICGGNAPLFHTWKDILALWKHADGFQITNMQPVKGYGWRSMQVAVSWLSWYKWVRPDEMDSENASIAIIERSRDKSLDPVHILMLGPPTNLARAIDSDLLDQSGISHVYLMGGELTHQQLDLNFRTDRASARTIIEESNIPTTVIPIQTCAQTIVTESYLERLDCPSVAACALLPKMKQQIKLMPRFVNQAVKKRCTIDGPWRPSPNLDSGFIPWDLVALLAITHEEEFIEWKYHRVSIPPCDDRIGEPCDSTMIINEDFGETFDGRDWKGVVRIPHKVRDEEKLLDVMFTLLNEVPATSQQPPALFFGFYGEVLLSICLCIVIIIYMKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTK4</accession>
    <name>A0AAD8XTK4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016264</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000054">
        <property type="protein sequence ID" value="KAK1733126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTK4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08161">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042007746" description="SET domain-containing protein" evidence="1">
        <location>
            <begin position="32"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="128"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="353" mass="38833" checksum="A65C0E7C10FE91FB" modified="2024-05-29" version="1">MMALFALATHFLMLTSLKNSLMQLLLPQAAAFLINHRYGCHYSPPRSLAALRATSTLDDPNIQHINQLLMDKKQELLDGLLDDPCKLSEQSPLSIVAADNDLRDAYLTTEQRVYETLLSSRLDLPFLNRAIVGPSEIEGAGRGLFATEDIKEGDVITCYPGDALLCELPSTDEGGEGDPFDLEDDENEAVDEVVLWGRHVPKGDRWDDDTVFDGSKSSPPLTSYAVTMSDVYSVMGHPSLDDNPAYIGHFANDGAGHLAYEMPDSPRNIEASLELGLDTESSEFGVEDNIAAYVLKSFDVANAMHQPVDDDEFHMVTVAIRDIKKGEEILVTYGPDYWISDYAGHIADAEDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XU74</accession>
    <name>A0AAD8XU74_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015247</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1733989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XU74"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="303"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="465" mass="51082" checksum="5489EFA4971F4AB0" modified="2024-05-29" version="1">MSTAPHKPNNMKSSPPNVHRSEDIGVEVQMPLSYWDKWTPGWGDDVADASDAASVVDDDAASSGNVAGSRMTIKKKSLLAISIAAVSIGGIFFALNGTKNTATKAVDTSKLHKVEVDALDLCEDVRRVLVVPGSEEFQTARESSDKARHMRILNLKGSSAERRKKCVRNRDKKRDDDKCARKRKPNKTSTKEAERKLGQPSSFLTTRSPGPTLCRDDSREDNLPDKPRVDPLPATEPPTPSPRRTSAPTKAIITEATPAPSKREVETDKDETDQPTKVTPSPTPVPTDQPTKVTPSPTPVPTDQPTKVTPSPTPVSTTANQPTNCESTETGFLGYDLVMNDALKLLVNEGLEVKRIAKKNQKVQFINGEKSDITYHEWMDGAGVIPWMKEDTSMYQIRRTMMAQAEYGVSISMQNMKLLDSGSSWVTRHGIALVECRLGRHGLVARKLRLVNAMKLIRIPIANIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUU7</accession>
    <name>A0AAD8XUU7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">QTG54_015272</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell envelope</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the polygalacturonase-inhibiting protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1734014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000363">
        <property type="entry name" value="Leucine-rich repeat family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000129">
        <property type="entry name" value="Leucine-rich repeat receptor-like kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000095">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase GSO1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000400">
        <property type="entry name" value="Nuclear pore complex protein NUP107"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013210">
        <property type="entry name" value="LRR_N_plant-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051848">
        <property type="entry name" value="PGIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48059:SF30">
        <property type="entry name" value="OS06G0587000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48059">
        <property type="entry name" value="POLYGALACTURONASE INHIBITOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="17"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08263">
        <property type="entry name" value="LRRNT_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="18"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="149"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="Leucine-rich repeat-containing N-terminal plant-type" evidence="14">
        <location>
            <begin position="457"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="Leucine-rich repeat-containing N-terminal plant-type" evidence="14">
        <location>
            <begin position="855"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="domain" description="Leucine-rich repeat-containing N-terminal plant-type" evidence="14">
        <location>
            <begin position="1007"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="domain" description="Leucine-rich repeat-containing N-terminal plant-type" evidence="14">
        <location>
            <begin position="1146"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="domain" description="Leucine-rich repeat-containing N-terminal plant-type" evidence="14">
        <location>
            <begin position="1400"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="13">
        <location>
            <begin position="1561"/>
            <end position="1717"/>
        </location>
    </feature>
    <feature type="domain" description="Leucine-rich repeat-containing N-terminal plant-type" evidence="14">
        <location>
            <begin position="1809"/>
            <end position="1847"/>
        </location>
    </feature>
    <feature type="domain" description="Leucine-rich repeat-containing N-terminal plant-type" evidence="14">
        <location>
            <begin position="2193"/>
            <end position="2234"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="15">
        <location>
            <begin position="2361"/>
            <end position="2589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="185"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="2325"/>
            <end position="2349"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="118"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="188"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1734014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2646" mass="290769" checksum="C90BF22D59F0D70B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV46</accession>
    <name>A0AAD8XV46_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015433</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV46"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="203" mass="23486" checksum="6FA986163A89A939" modified="2024-05-29" version="1">MQMVQMMEMSWVHLMEKHLGQMTEMNSVHLKEKPKELRSVCLSVDMMAMQKVLMTVIGSVQLMETQWAQLTEMSWVQLTELCLVMQKVIQMVLSSVCLSAELTAKLKVLMLDSPMVMSLVCPLAARMAMQKDFQMAHMRPMVMQKVPLMESGWVHPTELCSEKRTVTLMVKSSVCLLVERMVMQMVQMMEMSLVHLMEKHWGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV83</accession>
    <name>A0AAD8XV83_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015108</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV83"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="244"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="411" mass="46709" checksum="6EF72BEA91F67881" modified="2024-05-29" version="1">MVLHSTITEEEEVPLSAPDLSSLSPLPSLEAASSSSSDDMSPAEQEDGNDILSSPSNPASSTIDAPNNNSEPHRNEEHGDVKAATKLWLDSMLSGYSFIWRLSIVLVVILSWYYAYPITGNSEQQDEMLEYEEEEYEEEEEYDPWSIWGDGFDYTKDREFWISDEDLPEDIATDLQSTNEEIQLEATARRQLDPMKWDTFDYWEIYHYFACAKVFTSPRPVWSEQLFRDTRDFYNDFVENDNTPFIGLFRSTYQANDDVYDMSQNAIPYLSGGEKGRGLKAARDIKEGEVIFKATNNTIIFNDGHTLRKFLFAMNDRFSDPGMVCDILIWAWVQDMPCGTPFAGVVDLDNGNLLNDWGLGGSYEEQDYSANIRCKGAALSCYASKDIIEGEELLGDYSDFVSYHAWADLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWR9</accession>
    <name>A0AAD8XWR9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutamine--fructose-6-phosphate aminotransferase (Isomerizing)</fullName>
            <ecNumber evidence="3">2.6.1.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.16" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWR9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006047">
        <property type="term" value="P:UDP-N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937">
        <property type="entry name" value="GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937:SF0">
        <property type="entry name" value="GLUTAMINE--FRUCTOSE-6-PHOSPHATE TRANSAMINASE (ISOMERIZING)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SIS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SIS" evidence="2">
        <location>
            <begin position="265"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="408" mass="44222" checksum="E6E484E1D580A642" modified="2024-05-29" version="1">MEGNKSVNDATEQALSRCDESWGLCVMCTDAPDQLVVARNGSPLVIGIGYDRTFIASETSAFNRYTKNFVSMNDGEIDPLKLKEYVEQPEATARDLGFGGRLTYDNVQLGGLEKMKDELRRVKYLTLSACGTSLNTAQYAEKLMKHLGSFDMVHSLDAAETDSNDFPRKSEKAKEYAFLVVSQSGETKSKEKDITIVSVVNAIGSLIARTTKLGVYCNAGRENAAASTKAFTTQVTLRGKCNDVTEQSAEAASLKESLMRLPISCGMALKNRELCQHVAERNGKPVAMEGALKIKEMCYLHAEGYSGGALKHGPFALIESGENGKHGQGATPIIMLILDDNHAYHMRTAAEEVKAREAEVIVITDKAELVNGIDDKPIVIPSNSNGPMAALGAVMPIQLIACELAMLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYP3</accession>
    <name>A0AAD8XYP3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WRKY19-like zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013506</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYP3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056866">
        <property type="entry name" value="Znf_WRKY19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24906">
        <property type="entry name" value="Zf_WRKY19"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="359" mass="39245" checksum="7BFBC9FEC6B11D47" modified="2024-05-29" version="1">MAAPNDSSGEDDDDVGALIYRESQLRKAEAAAAAAEGQKTTIASSHQRTSTRKRSPVSNQSKQSLPIPKRNGATNGRKREASNEDARPRKKVAKKKYRNECSADGCTKNVIRGGVCKWHGASVKRCSSEGCTNQAVKGGVCVRHGAKRKLCISEGCTNQVQRGGVCIRHGAKVEYIQCSSEGCTNYAQKGGVCIRHGAKRKLCSSLGCTNVSVKGGGGVCVRHGAKKKRCNSDGCTNQVQRGGVCQRHVAFRNTQQQEGGVEEVKKKLTSVKDRQPAEVLLKEFNEADDCLTEHSKDVSMKACEFQDVTNDIRIRILIGMWLSRRYQDFNVPQKLLDFEARMKGCKEQPILDKLSRAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZ78</accession>
    <name>A0AAD8XZ78_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013027</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZ78"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042004835" evidence="1">
        <location>
            <begin position="22"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="232" mass="25569" checksum="A3B2F1422F154A55" modified="2024-05-29" version="1">MTKTTFYYALLLALCQASVSSAWVTVANNNVNLSYNKQAQSSETKLYAQDRRHFVTSSLSIIGSCALTGTTLLTPLPSHAATSPQQQKDKDNIVKGYNRLQYLLDNWVDKTTVCKIGQETTFGDKCERTPVVVMEYLGFKSTSDPLFKADTAMLRLKDLVPSDREVDFYDAVDAFAQNAEEASSMAFVSSWGEANPGGGKDRVALFIERAKNNVIASRDALKTIIDILDLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0Z2</accession>
    <name>A0AAD8Y0Z2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">C-terminal processing peptidase</fullName>
            <ecNumber evidence="6">3.4.21.102</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_011887</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S41A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.102" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0Z2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07560">
        <property type="entry name" value="Peptidase_S41_CPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.44">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004447">
        <property type="entry name" value="Peptidase_S41A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32060:SF22">
        <property type="entry name" value="CARBOXYL-TERMINAL-PROCESSING PEPTIDASE 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32060">
        <property type="entry name" value="TAIL-SPECIFIC PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="PDZ" evidence="5">
        <location>
            <begin position="330"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1737601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="773" mass="84771" checksum="1AAA3F72B4D19738" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1M2</accession>
    <name>A0AAD8Y1M2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012088</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1M2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="125" mass="13813" checksum="E8C486634CEE15D3" modified="2024-05-29" version="1">MSEGAKIRAEELTRSSSRYHNKPTLLSIQRCNMKLISFAAASLFASVSNSALPPGYEDELWCQPGNCEIYTNPYGIVGARSTFEKCYDPETNVMSEGVWTGSETDVTVPDGFIQPQICTAEQYSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1Q4</accession>
    <name>A0AAD8Y1Q4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA pseudouridine(55) synthase</fullName>
            <ecNumber evidence="2">5.4.99.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_011270</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase TruB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1Q4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160148">
        <property type="term" value="F:tRNA pseudouridine(55) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990481">
        <property type="term" value="P:mRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01080">
        <property type="entry name" value="TruB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014780">
        <property type="entry name" value="tRNA_psdUridine_synth_TruB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767:SF2">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE TRUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767">
        <property type="entry name" value="TRNA-PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pseudouridine synthase II N-terminal" evidence="6">
        <location>
            <begin position="107"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="271"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="297"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1737976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="407" mass="44109" checksum="A6F9E5C37AD82B9F" modified="2024-05-29" version="1">MKRARPVAVAAAISDNNATNKRVMLAASNDLSTSSSLSSITDPSKTTSATTGNTESTPLYLAEGLIAIHKPLTWTCNDVVSYIRGILSRDAQSRGFEGKMRKRGKPVMKVGHGGTLDPLASGVLVLGIGKGTSKLQSYLEGDKQYTAMVELGYETTTLDAEGEIVKTMDWNHVTSIDSIRETVVPKFTGKIQQVPPLYSAIRVDGKRLYEIARGGDEKEVEDVEIPMRDVEVYKVEVENTLSESVIQSGVVDGKKYKEAVQEMEAAAAAAAAEKAAAAPPPAEDVQESNDEANNTAGKKKKKRRGNKNKGTKKKSFFDESTVPTVTVQCDSTTATTSFELPLFTLNVSCGGGTYIRSIVRDIGYEMDTVATMTGLVRTKQGPFLLEDALRKEDWNADNIYEAMTKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1V7</accession>
    <name>A0AAD8Y1V7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">WRKY19-like zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011657</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000024">
        <property type="protein sequence ID" value="KAK1737673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1V7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056866">
        <property type="entry name" value="Znf_WRKY19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24906">
        <property type="entry name" value="Zf_WRKY19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="1">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="296" mass="31364" checksum="086BB2D0327CFF38" modified="2024-05-29" version="1">MYRPGKKTAKQGAKKKKLCSSEGCQNIVIKGGVCTKHGARRKTCSSEGCQNISVKGGVCTKHGANVKHKKCSSEGCTNQVINGGVCIRHGAKIKTCSSEGCTNLVQTGGVCFRHEAKRKKCSVERCTNIVINAGVCIKHGAKRKLCDSEGCTNHVVQGGVCRRHGAKLELCSNEGCSNLAQKGGACIRHGAKKKKCSSEGCTNLAQKGGVCIRHGAKRKLCSSEGCTNHVVSGGVCRRHGAELKLCSSEGCANIVIKGGVCKRHRAKKKTCSSKGCTNQAQKGGVCKRHWAERVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y249</accession>
    <name>A0AAD8Y249_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">HPP family transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_011721</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y249"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007065">
        <property type="entry name" value="HPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058581">
        <property type="entry name" value="TM_HPP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33741">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN DDB_G0269096-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33741:SF5">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN DDB_G0269096-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04982">
        <property type="entry name" value="TM_HPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="393"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="496"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="domain" description="HPP transmembrane region" evidence="3">
        <location>
            <begin position="353"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1737435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="579" mass="63846" checksum="51937C99C98B1066" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2H3</accession>
    <name>A0AAD8Y2H3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2H3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="419"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="188"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="480" mass="53502" checksum="C1B51BA5F536063F" modified="2024-05-29" version="1">MEGVANKRKPYGLSNDKVNGFRQRQGNVVAKEAAAGTATTNSSRDRSLSTRRMSSTRSRTTSKRRNHDGKVDTRGRSMCRNKNQASASPADDQLRSKSCSRKHRKSRSSSQRLLSSPTYRSSTQDAERSQSSRPKSIVRTVKSSVDVSDYGRSPGDVGRSRSMSRSRSEAPNQGGAAALSSAFSTHQGKSSGNSKAAASTPRRFFVEVDENMNILKLKEVNDYSETNAIYKPVLTSGKDRTNRRRSSSFDGRQPTRDECRQNRRRSSSCEPMLTRSSALRSSLVRSSFTSRSRSGLNQSVSFSIHDESTEDTIKRVSSYSRQVPQIRDVVDFDPRLKESSSTQATSTINDDEEDSFGFLQPATFWDNSESEDANDSNLQFGVASNLAIVASVEEAEEFDQDKSELSSYTNTSSRRKFFGKKSTRRAVPVNTHSHRSEREEKETSVLMTGAANCLEAQQLSATCKSKRVSRLYKMINNRYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4D0</accession>
    <name>A0AAD8Y4D0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ionotropic glutamate receptor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4D0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015683">
        <property type="entry name" value="Ionotropic_Glu_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18966">
        <property type="entry name" value="IONOTROPIC GLUTAMATE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="355"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="544"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="715" mass="79711" checksum="4D6037DB3D15EB50" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y596</accession>
    <name>A0AAD8Y596_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_009597</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y596"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="18"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="83"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1739838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="316" mass="35011" checksum="3892167B953E0CE4" modified="2024-05-29" version="1">MSSKTEAVDVEADEIMYCASCGTAGVDNIKLKKCNACNLVRYCGVKCQREHWRQHKGACKKRAAELRDELLFRQPEHGDLGDCPICLLPLSHDFDKSSIQSCCYKLICNGCAYASFLHEDEGSLEDLCPFCRQPYPESEEEIEKNVMSRIEANDPIAMRQMGVKCYTLGNFRGSIEYLTKATKLGDAEAHCQLANSYMIGQGVAVDMKKAFYHFEEAAILGSVTARYALGVIKESGRGGKTEKAVKHFIIGANLGCDKSLKCLKEAYAKGLVKKEDLAAALRTHQAAVDATKSPQRDAAELAEKNEESTFFKKEFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5K3</accession>
    <name>A0AAD8Y5K3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-CH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_009074</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5K3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-CH-type" evidence="4">
        <location>
            <begin position="11"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1740124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="434" mass="48712" checksum="DAC5A138A0DBA3D5" modified="2024-05-29" version="1">MSNSSQSAAKTPSCSTTSCWLCLEEGPDDSGAPLVRDCSCRGHSGFAHLPCLVQYAESKSRDIVERQTHVMSDIFEENFFEHCPNCKQEFQGDLYYDMTKAQLSFVEKELKGANGWHIGALQQRILALDGKKEADRVEGEEICAKMLTLIDNMKKNGDPQLDAFNLASVYHVIARFNYQLGTNPCLERAKHYFEKARDIIVTLGDRDIAMAMEGDIAQVQERLSGNNLPTKKESVLSVQRARYNHMLQATTDQNDVRTMQVGVHLVTVLFEAYHTLEALRLLEKLVGTSRRVHGSDHRVTADTAFLLKQFQARYVSIGNGLNYQALRYENDGKSCVIQGPVPRNIFEPRNVDDEKTFSVPTANIYFSLGSPVMLHGLKKAAHLNGEIGDVRGYCELTDRCVVHLEGKDLKPVKVKHENLRIVIDVADPKKESSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6E3</accession>
    <name>A0AAD8Y6E3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Actin-like ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008684</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6E3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="448" mass="48460" checksum="9F9466D6D367F651" modified="2024-05-29" version="1">MSTHQTIVVELGCSRIKVGFAGEPKPRRVLSSGDGGALGIDDGMCTSSCTWNHFYSYLSSSSDAVIGGDNNAHSIATSSYDWEKTLYPLFSYILTSILFIQRPSRHRILVLMNDIFPPRHLREALLRVLLDYLNLGSVLLVNGGGFGSVQYLLEGMNLSSYPLITQQPKASLVVDIGTNEARVAVLVPGSLFLVETYQAIPAGYLAFLRKVLALYQEANENWTTNATVEDANVIVQAWMSAPNTDISTAATTISVELPTLMKQSNDPSEASTVSSTIQVSVEPLLEAFHQVYLDYTQSTSLVYAILNSVLASPIDFRKVALQNIILLGGGSVALRSFGKGLKMEVETAIKSACGVSLGDDTLAMEEEKKDDGMEVSSIAQGRFQSLKAAVERSDGQEGGVQVKYPDPFAADVAHWIGASVMGKLRLSNEDWISASSSAVSARGERLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6X3</accession>
    <name>A0AAD8Y6X3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">GTP:AMP phosphotransferase, mitochondrial</fullName>
            <ecNumber evidence="7">2.7.4.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Adenylate kinase 3</fullName>
            <shortName evidence="7">AK 3</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_009489</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a ribonucleoside 5'-triphosphate + AMP = a ribonucleoside 5'-diphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:13749"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.10"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the adenylate kinase family. AK3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.10" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6X3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:AMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046899">
        <property type="term" value="F:nucleoside triphosphate adenylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006172">
        <property type="term" value="P:ADP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046033">
        <property type="term" value="P:AMP metabolic process"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046039">
        <property type="term" value="P:GTP metabolic process"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046041">
        <property type="term" value="P:ITP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000106">
        <property type="entry name" value="Adenylate kinase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006259">
        <property type="entry name" value="Adenyl_kin_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
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        <property type="entry name" value="Adenylate_kinase_lid-dom"/>
    </dbReference>
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        <property type="entry name" value="ADK_active_lid_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="AK3/Ak4_mitochondrial"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01351">
        <property type="entry name" value="adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05191">
        <property type="entry name" value="ADK_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57774">
        <property type="entry name" value="Microbial and mitochondrial ADK, insert 'zinc finger' domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 7 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Adenylate kinase active site lid" evidence="9">
        <location>
            <begin position="188"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="NMPbind" evidence="7">
        <location>
            <begin position="95"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="LID" evidence="7">
        <location>
            <begin position="187"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="74"/>
            <end position="79"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="122"/>
            <end position="124"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="151"/>
            <end position="154"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="197"/>
            <end position="198"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1739730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="286" mass="31995" checksum="55C9EE07A28EBEA5" modified="2024-05-29" version="1">MMQAFVSPAFRRTVVGKSSSLLHRRSPTTVVRSFASIYHADMEDLSHEETSSPSSTSSPSSSCAHSLLILGKPGGGKGTISGKILSDFPQFRHVSTGDQLRQHVRNETKLGLEAKKYMDEGCLVPDNVMIKMVMKDAVEAIKNGQSLLLDGFPRTMEQAVALDEQLDVDMVINLCIPNETIIERISDRWIHPASGRVYNYSYKPPKVTGMDDETGEPLVQRDDDKPESVLKRLNKYEEATRPLVQYYEEKGVIQTFRGTQSDVIYPEVQEWLGEQLAEDDVEANTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8A7</accession>
    <name>A0AAD8Y8A7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008106</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8A7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042215656" evidence="1">
        <location>
            <begin position="20"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="218" mass="24443" checksum="11E04B9698D83A11" modified="2024-05-29" version="1">MKLTLAALLLGMMSRMSSSATATPDTFVGSFTQMIFEGLGCKEDNFHERIRIEVDITRSLVVMEENMFCESDVHNTFSGQNYTQLGAYTTACDDDEKTVLFTWYACHTTDCSDCDDTISMRWKTPMSVWDEPTDETCFEMDIQPPYDPIVDLTEGISYRLTGDPSTHASIVVKNSCMSKSLARGNTLSSKPSSSGRWVGLNVCWYYLVASVGFALYYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8E9</accession>
    <name>A0AAD8Y8E9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex</fullName>
            <ecNumber evidence="7">2.3.1.168</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_007885</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.168" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8E9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016407">
        <property type="term" value="F:acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043754">
        <property type="term" value="F:dihydrolipoamide branched chain acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031405">
        <property type="term" value="F:lipoic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="entry name" value="E3-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050743">
        <property type="entry name" value="2-oxoacid_DH_E2_comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43178">
        <property type="entry name" value="DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43178:SF5">
        <property type="entry name" value="LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE COMPLEX, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="6">
        <location>
            <begin position="96"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="52"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="53"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1741407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="356" mass="38565" checksum="9E92C6F7696B0069" modified="2024-05-29" version="1">MWEVGEMMFVGKPLLYIAVDNAANVGGVGGGAQQHAAAESVDETKQQATLHNVVDESDRLHIPTDESVHSNSDSHYGGRKGSESEGEESGIMAKVLSSPAVRKMSKDYSIDLGAVMGTGPGGRVLKADILNIINARDSTAKPTGSTTVPSLIRIIADRRRHRHSNPWVQPPNGKEYDDISPSTTHGFIIGYYQYPVLNSTIDVEEMTLTYHQSHNVGVAVDTERGLTVPVVKRCQDKSVLEIAEELGRLYALAFEGNLSEADISDCTFTLSNIGAIGGTYMSPVVLPPQVAVGAMGKIQRLPRFVSDTSDEVESVRIMPISWGGDHRAVDGATMARFSNLWKAYVENPSSMMFAMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y972</accession>
    <name>A0AAD8Y972_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_007415</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y972"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1741842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="342" mass="38255" checksum="7CB3D6A18B752C0C" modified="2024-05-29" version="1">MIVNQIFDKCVHDLEINGGYALLPLSELQSSLNNAISNAFDTARCAFDDIECGDDCSGDGALMHLIDPSTDSGGWTGYHKASHLNGRYNQHRQGFVFSNGEFFNLHSNVDFESDMKQFFHFSHDVVASGVLRAIERRLELPDCYFDNELGPTDNSSQWHLKQYQVDELDEHSNDTPPLSQQHDQKVLLPMHTDPSLISVVIIDSPGVNKGGKGLEVFQANCSEDTVPNDCKTKHSRGIWKAIPHHGRDVAIIFVGSVLSYLTKGQVFSAMKHRVVDDCKDDINDRMAATLFVRPQPGAYMKTLPSKYIEHGGASSTKLPPTFRVWNARVAKNYMKKKKKQKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9D3</accession>
    <name>A0AAD8Y9D3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007646</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9D3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="111"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="155"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="216"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="37"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="133"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="535" mass="62320" checksum="FCD71B4CA6604AC0" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YA72</accession>
    <name>A0AAD8YA72_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_006283</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YA72"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000003">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895">
        <property type="entry name" value="CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895:SF32">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CHK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="9"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1742686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="180" mass="20284" checksum="B5343F378A4C85C1" modified="2024-05-29" version="1">MKKKTVGDYELGEKLGTGTFGKVRRARHVITGKEYAVKCIDKTMLEKQKMRTQLKREVSITKLIQHPRVVQLFEVLASKTKIYLVLELVTGGELFDELAKEKGGFGEFKARRFFKQLVDGMMCCHDKGIVHRDIKLENLLLDCNGDLKISDFGLSALHDSTCGDATMTQSKMLHTSKCAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAJ1</accession>
    <name>A0AAD8YAJ1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_006478</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAJ1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38909">
        <property type="entry name" value="G PROTEIN GAMMA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38909:SF1">
        <property type="entry name" value="G PROTEIN GAMMA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042069264" description="PDZ domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="4">
        <location>
            <begin position="439"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1742881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="513" mass="56236" checksum="7220C3FA903449C3" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBA2</accession>
    <name>A0AAD8YBA2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBA2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="387" mass="43852" checksum="C87C684181EEAEF9" modified="2024-05-29" version="1">MSTSSTLPQPPLGGNEQPYSYVPYDGLETDWLGDELRLRSCLINSPSSESNDKANCNHGGRYAPGTLVWVLLSKKKPKDAQNCNSGFHDTALHKKRRNKKNKGSGSGDAESEESNQASSSKQNIDDQNNDHGHESNQATLYNRSKKEFFLRARVISDDEVVNDETSEQERSKRRVLVRYSKGATYRVRAYNLLSVLEPSVHKDALPPLVVVTPETHIYRRIAKVHTTPEDSFMEIGCDYGITVDKIQTSIEEAGNVPKEWPSETKNEVPIDEKKEDDGNSARVSCVGVDRSIESIDIAIKRYKCKFLLVNVLVPEEMDTLRTTCESSLQGEAPSIICVDINGNREIDGVLRCVQMIMNEKWKRQPRMIIVKSRFLYWDLKERKKQQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBU2</accession>
    <name>A0AAD8YBU2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Chromatin-remodeling complex ATPase chain</fullName>
            <ecNumber evidence="14">3.6.4.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_005984</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="14"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBU2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034728">
        <property type="term" value="P:nucleosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17997">
        <property type="entry name" value="DEXHc_SMARCA1_SMARCA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000082">
        <property type="entry name" value="ISWI chromatin remodeling complex ATPase ISW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000015">
        <property type="entry name" value="lymphoid-specific helicase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044754">
        <property type="entry name" value="Isw1/2_DEXHc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623:SF49">
        <property type="entry name" value="SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09011">
        <property type="entry name" value="HMG_box_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="11">
        <location>
            <begin position="23"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="369"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="673"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="9">
        <location>
            <begin position="23"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="89"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="289"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="89"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="133"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="165"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="178"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="225"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="295"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="918"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1743363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="918" mass="105357" checksum="7E8AF9D7D9CD1217" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCH7</accession>
    <name>A0AAD8YCH7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cysteine and histidine-rich domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_007100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCH7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1130.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007051">
        <property type="entry name" value="CHORD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039790">
        <property type="entry name" value="CHRD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46983:SF3">
        <property type="entry name" value="CHPADIPLOID STATE MAINTENANCE PROTEIN CHPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46983">
        <property type="entry name" value="CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04968">
        <property type="entry name" value="CHORD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51401">
        <property type="entry name" value="CHORD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CHORD" evidence="4">
        <location>
            <begin position="133"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1742535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="309" mass="34227" checksum="B69A9223738F2932" modified="2024-05-29" version="1">MKVFLRYEDNEDESKHKTLKITLPKSWKNGPSSRLLDQFVESYNGGNEGQSNPLESAGMHLALRRSSATAANDDTATTSLEDVPSDGIIIETIADRDDVFVCHGPSRTVEEINAERQAKLDQEKEAQKNLSKCVHFGCNQRFPRGGPYPDCKYHTGPPVFHETAKFWSCCPNKKAYDWDGFQTLPACQQGKCTDVKDEENNQKQFLGGCDLREEMNGPKLKSIDDFNASAAAGGSEGAPVLERLRSVLGELGVENELFDQVLEGVKKEEMTKNGLQEDDAKVVDEATKTLGLKLKKSLKAIAVEQLRIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDD7</accession>
    <name>A0AAD8YDD7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CCR4 C-terminal deadenylase domain-containing protein</fullName>
            <ecNumber evidence="3">3.1.13.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006076</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.4" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDD7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004535">
        <property type="term" value="F:poly(A)-specific ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002782">
        <property type="entry name" value="Mut7-C_RNAse_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF34">
        <property type="entry name" value="PROTEIN ANGEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01927">
        <property type="entry name" value="Mut7-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mut7-C RNAse" evidence="2">
        <location>
            <begin position="507"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="897" mass="100420" checksum="6C8D9C8CACBCEA80" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDG6</accession>
    <name>A0AAD8YDG6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Riboflavin synthase</fullName>
            <ecNumber evidence="4">2.5.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_004700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.9" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDG6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004746">
        <property type="term" value="F:riboflavin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00402">
        <property type="entry name" value="Riboflavin_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001783">
        <property type="entry name" value="Lumazine-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026017">
        <property type="entry name" value="Lumazine-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098:SF0">
        <property type="entry name" value="RIBOFLAVIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098">
        <property type="entry name" value="RIBOFLAVIN SYNTHASE ALPHA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00677">
        <property type="entry name" value="Lum_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51177">
        <property type="entry name" value="LUMAZINE_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="226"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1744167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="265" mass="28816" checksum="5BB007A4525B3377" modified="2024-05-29" version="1">MFTGIIEEMGEVISLETRDDMTLWDGSKGKGTECVNGVCLTATEIDEDAKTFKVGLAPETLRKTNLGTYVPESKQRVNMERASEIGGRNSGHFVQGHVDNVGTIMDQWIDENSLFFKIAFPYEFMRYVVPKGFIAIDGTVRMKIILPSKKVGDTVNVEVMFLANIGASVGAFVPKMEALETKVKQLEARLQELEGGESTASSSATDNDVNYGQPIGGLSNVAAAATAPTPEQVKVKNTDGTEWSPGWSRWADDPSLDWVRIQGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDW6</accession>
    <name>A0AAD8YDW6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cyclin-D1-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_004925</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CCNDBP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDW6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1410.10">
        <property type="entry name" value="I/LWEQ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026907">
        <property type="entry name" value="GCIP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049317">
        <property type="entry name" value="GCIP-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049318">
        <property type="entry name" value="GCIP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15492">
        <property type="entry name" value="CYCLIN D1-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15492:SF1">
        <property type="entry name" value="CYCLIN-D1-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20936">
        <property type="entry name" value="GCIP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13324">
        <property type="entry name" value="GCIP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-D1-binding protein 1-like N-terminal" evidence="8">
        <location>
            <begin position="176"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-D1-binding protein 1-like C-terminal" evidence="9">
        <location>
            <begin position="229"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="46"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF20936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1744392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="421" mass="46035" checksum="D868052481F78018" modified="2024-05-29" version="1">MNAEVLESLTCLADTLTKLNEREYHTGTIDGDDTTKDITEATAAMSLSSQQSTPSSNEQQQQEEEQQTVGYWRSLPTEVTAAYQLLADGAEYIHATSTKYALVGKIDSHEGGNLALELRKGAQLIGTGTLLLFSPECGSSRSLRHYGGHIITTLIGRAYEDGSAQGNPNDGNNVGAQKTGAVWSACDGLRLKLPKGNRAAMRRELMIWVRDCNESIEEFDEMLALGPRDDDDDEEEEEQFSESEMKVARAAVNIMKCSKNTLGLVLKVCECVGESLDESTAGDENNKELLQLITNMHEVARRIGEGVTNFGVMLYPPLEASTNEEEFEQWQSTKASKTFRLDGEMDIPSLGSTSLGLQLEHQLHALAECVICIKKSELTTVTGEAIQTCYSEEVNDAVKKLMEAIPVRCKDSVGGVTSWCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDZ0</accession>
    <name>A0AAD8YDZ0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WRKY19-like zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005630</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDZ0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056866">
        <property type="entry name" value="Znf_WRKY19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24906">
        <property type="entry name" value="Zf_WRKY19"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="298" mass="31608" checksum="0B87B9C069174793" modified="2024-05-29" version="1">MASKEDEVKASGSDKKGEEAVMETTEVLKKEAEKNEPAAAAAAVPDGEASTNNVKRKSKKRKQRDEQSKEDQPKTKAPRKKPQCSAEGCTKYPQRGGLCIAHGGKKKQCSSEGCTNQVRSGGLCIKHGAKVSTCIKDDCTNQAMLGGLCTKHGGNKKKMCSTEGCTNQVVNGGVCMRHGAKVKKCSHEGCTNYVQNNGVCQRHGAKTKPCTVEGCTNKQQKGGVCIKHGAKHKQCKSEGCTNIVVNGGVCRKHGAKIKLCSTEGCPNIVKKGGVCKRHGANLLPPMKKKGIVGICTKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEP6</accession>
    <name>A0AAD8YEP6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEP6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="92" mass="10567" checksum="F66FDAC8B8B0EC2B" modified="2024-05-29" version="1">MTPDEIQMATKWSKQSHASTTTYQEISLEETPFISARMKFNIPSLPLEPESTGDSDLEVEVQMEDAVENTVPEKQRRSKRRILLSPGQSMYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YF64</accession>
    <name>A0AAD8YF64_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">1-acyl-sn-glycerol-3-phosphate acyltransferase</fullName>
            <ecNumber evidence="10">2.3.1.51</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_005437</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.51" evidence="10"/>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YF64"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003841">
        <property type="term" value="F:1-acylglycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006654">
        <property type="term" value="P:phosphatidic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07989">
        <property type="entry name" value="LPLAT_AGPAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10434">
        <property type="entry name" value="1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10434:SF64">
        <property type="entry name" value="1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042079577" evidence="8">
        <location>
            <begin position="20"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="9">
        <location>
            <begin position="159"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="370"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="380"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1743840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="397" mass="44341" checksum="F97379B7A7AB1E2B" modified="2024-05-29" version="1">MNGKFRGLLLGAAFLCSHGFSPPRVMSPPAYKQHVPSAAKLVSSSAKQTRNTSRLYSSAAVSVTDLQAVSPPERKLNQLQSAVVRTLMVAFIMSMCVALPVTLFPVWVLYRLKIINRVQKEMISLRVGQFCSRWLMRLFPFARKKVIVEPETLTDPQPAIWVCNHISMLDLFFVLALDKKMRGKNRRPIKCLYWKGLESNPITCLLCKMAGFIPVDMSDNGNGNANEYDPKSFKQMLRATKNAIKDGFDIAILPEGQPNPTPENGLQPVFSGAFTLAKMSRRPIQMIALHGLHKMWHPDENIGMACTARDMAARVYPGSRVYKDAEEFSSTFSAVVGHFGAHGKDLDDTELQLWLDGTMWETELSRRAATRMTAEDVVDDKESKPSKVEEGARSTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFQ1</accession>
    <name>A0AAD8YFQ1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004329</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFQ1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="251" mass="26575" checksum="6ECDD59117175E8F" modified="2024-05-29" version="1">MMGIKLTKLLAASVILSQYVFTCAFTTPFSLRTVSYQHDCIKLRVTTSTSEELAVQIRDGVSEQQTLSSATSQDIVVVDGMPTPILVDSEEDATNTYRAGLITIGFITLLFASNSPILRSAWESTSSAPPVLLINAAVSVVGLVGVIASSPFLNQIVNDPSAQGNTSKDANNNGNDLAARIIGSSAIAGVELGLWKFLGTTTNIVVIMYINSTHNTDSASSSRNNGSTDTKANMGSNRAGIGRRCHLHPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFZ1</accession>
    <name>A0AAD8YFZ1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SEC14 family lipid-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_003808</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFZ1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="210"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="273"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="CRAL-TRIO" evidence="3">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1745884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="360" mass="38897" checksum="87738EE95D8BF3FF" modified="2024-05-29" version="1">MTYLKQAGDVNSLHYPGSMRRAILVQAPFWLGSMWRAIKGILPASVTADLLSGTQTMNGGLKQYIAEDQIPVEYGGTSPFKLGEHPFEVGLKKLAESHADEIDAFDEAPAMSYSESSPLTSPQEDSPPRLSNRPRRQHHDNIVVSRQAQSNTASSKRNTLPQGWDGLGASYILVVASLLQLCSYAVIGSIELSMPLWVVSPDGMGYESRRTGMACFGTCFIILQALKRMKPHLSSRSIQKNPSRSVQIGILTSCISLACINLIPLTSKHDKSLLGLLCLSTLGAFIYLGLVLGVMAVDHLRATAISSSTDCSDLPSGLAFMQSHKSSPVLVFLGRLSAQSSSIRAVKEIPEIKPPPVGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGU4</accession>
    <name>A0AAD8YGU4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterogeneous nuclear ribonucleoprotein Q acidic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004363</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGU4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21039">
        <property type="entry name" value="NURR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041337">
        <property type="entry name" value="hnRNP_Q_AcD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18360">
        <property type="entry name" value="hnRNP_Q_AcD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterogeneous nuclear ribonucleoprotein Q acidic" evidence="1">
        <location>
            <begin position="13"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="91" mass="10338" checksum="16934CCC5151ACBC" modified="2024-05-29" version="1">MVDKTAIPQGDKLTDRVLARLDLLVQSGYCTAQELDMKVKTKLKMLPELDALNAIDEINAVPRAEIRNFGSYFMGILNRYMRDAIYSELTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGU6</accession>
    <name>A0AAD8YGU6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004207</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGU6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="14"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="182"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="493"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="696"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="269"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="332"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="346"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="526"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="537"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="753" mass="83163" checksum="46723032C68772EE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHF3</accession>
    <name>A0AAD8YHF3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003518</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHF3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="238" mass="25697" checksum="1A7C80950463462D" modified="2024-05-29" version="1">MPPSETDNVTVAAAPALLADEKLPSTNLPMQPNCPTLNECLVKSPSNVKEEDLNGTNNGVMENTDVGAMPPAAAAVEPAATAATTKDEGNNGSVTQDAPQTTNTNPNSEKITNDTPSASSSPRRRVKKRRSDDFVYADTKKEDKPSSSTQNIGAKKPPPPAAKKPKQRKRPQQCPSTDSILIDVPLLSQLTRSGVETYKAEENKTDSRLGGFGSWEEKGRWHQQQQQQQGCGEEEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHW0</accession>
    <name>A0AAD8YHW0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PSME3-interacting protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_002185</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHW0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039845">
        <property type="entry name" value="FAM192A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019331">
        <property type="entry name" value="FAM192A/Fyv6_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13495">
        <property type="entry name" value="NEFA-INTERACTING NUCLEAR PROTEIN NIP30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13495:SF0">
        <property type="entry name" value="PSME3-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10187">
        <property type="entry name" value="FAM192A_Fyv6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAM192A/Fyv6 N-terminal" evidence="4">
        <location>
            <begin position="5"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="111"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="168"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="178"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1746841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="236" mass="25711" checksum="3521A0B775309699" modified="2024-05-29" version="1">MSLSFVKSAVLSSTDGISHNEETTINTSETASIRASSTNSASHKPLFEQLRANKEIQDAKDDEFQKSIRGMQALDDEDVAHLDAIEEQKREVEYKVKSGIEREVALFHAAREDRGLVQTVVEDQVGDDDGDGSNKNDDEDKKSPGGDDTAKIFAAAAVPAAKKQIVPKFTIKKKRKRVDPESKDDAAQKKISGSTELKKSNNNDGEKKQAEEEKPKNNNVAALLGLGCYGSDSDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YID4</accession>
    <name>A0AAD8YID4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">SANT/Myb-like DNA-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_003160</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YID4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019185">
        <property type="term" value="C:snRNA-activating protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042795">
        <property type="term" value="P:snRNA transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042796">
        <property type="term" value="P:snRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000010">
        <property type="entry name" value="Transcriptional activator Myb isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000016">
        <property type="entry name" value="Transcriptional activator Myb isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051575">
        <property type="entry name" value="Myb-like_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621:SF1">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Myb-like" evidence="8">
        <location>
            <begin position="261"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="9">
        <location>
            <begin position="267"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="9">
        <location>
            <begin position="313"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="8">
        <location>
            <begin position="313"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="8">
        <location>
            <begin position="365"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="9">
        <location>
            <begin position="369"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="30"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="412"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="486"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="126"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="137"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="204"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="249"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="486"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1746553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="587" mass="63861" checksum="CB25CF5619917EE2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJ56</accession>
    <name>A0AAD8YJ56_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002302</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJ56"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="65" mass="7879" checksum="1836AEE193234E19" modified="2024-05-29" version="1">MSSGRACYNSQRVLREFHQEAFQYYNQMMERYESFASKESRKRFSLSQISHLFQSNRLASVQFQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJ57</accession>
    <name>A0AAD8YJ57_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002864</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJ57"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="73" mass="7833" checksum="B7EA0DF2934D18A2" modified="2024-05-29" version="1">MERRRPSHTSAMADITRDEGEELIGFILVAPLGSNTFVQRAASSSTNAKNMMGVSVSPKKVLCPRPVSPSIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJB9</accession>
    <name>A0AAD8YJB9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Prolyl 4-hydroxylase alpha subunit-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_003122</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJB9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF226">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042171050" evidence="8">
        <location>
            <begin position="17"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="466"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="Prolyl 4-hydroxylase alpha subunit" evidence="9">
        <location>
            <begin position="227"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="492"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="492"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="511"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1746515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="520" mass="56211" checksum="D231841C762C4EBF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJI8</accession>
    <name>A0AAD8YJI8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_002033</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJI8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042019921" description="Transmembrane protein" evidence="3">
        <location>
            <begin position="18"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="141"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1746689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="342" mass="37016" checksum="64DB697B36650D23" modified="2024-05-29" version="1">MMPSKLLLGSLAAASSAFILGMLSTSSCQFASVSFSLAFTQSEPVDDVFRMDTSPTNVIPIFLGLWRHQSFGIKNGSFFVADTCEEYSSQNIVDGNWVVARAFGILALVIGGVHALIISWLSFGSKKSFLRTFTCMKISPWIHLLCCLFQALTLIILRNEFCNQSLKQGIESLLERATIEWGDRCELELGSKMAIASVAFWFSAFILALVHVTGLPNRCPSLVKNSSANASANNSDRENEQNAVSIDEELDEEVATEVENPPTLVVPNATDSVASKPATGTSRETSTPAGAKSSPKTSPSKQNTSHNADNESRVSSVATRNVSILSSRVTSSTAGRRRAKYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJU1</accession>
    <name>A0AAD8YJU1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Dynein intermediate chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_001872</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein intermediate chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJU1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036157">
        <property type="term" value="C:outer dynein arm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045503">
        <property type="term" value="F:dynein light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036158">
        <property type="term" value="P:outer dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000924">
        <property type="entry name" value="Dynein intermediate chain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050687">
        <property type="entry name" value="Dynein_IC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442:SF7">
        <property type="entry name" value="DYNEIN AXONEMAL INTERMEDIATE CHAIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442">
        <property type="entry name" value="DYNEIN INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0243">Dynein</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="538"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="548"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1747909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="575" mass="64089" checksum="1FB6B64C18C3C2F2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YK07</accession>
    <name>A0AAD8YK07_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001490</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YK07"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="127"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="235" mass="27134" checksum="9ED47FB5E697BA23" modified="2024-05-29" version="1">MNETNSSSTNGSRPLPTNNGYKNGTHNSYNSLHSIDEDDEEDNDDTSLSTVVHKMQEYEELVTAFHSELQINHDELLSKDDVLWFFAELKWRFADIHRGVVTVSKEPTISNVQDNSEEWKNCLIGLVDELEYSIQKSKEEISDNNDKVEANLVDDESVAAMKRSYEEQLAAQSKRIEQLETDAVERDVQFAETQKKMKQDHHLIEEEKKKLSLSKDGTAARIRYLEIWCNLYKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKF2</accession>
    <name>A0AAD8YKF2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">RuvB-like helicase</fullName>
            <ecNumber evidence="12">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_000178</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the RuvB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="12"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKF2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002221">
        <property type="entry name" value="RuvB-like 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000010">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.360:FF:000002">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.360">
        <property type="entry name" value="RuvB-like helicase, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027238">
        <property type="entry name" value="RuvB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041048">
        <property type="entry name" value="RuvB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042487">
        <property type="entry name" value="RuvBL1/2_DNA/RNA_bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010339">
        <property type="entry name" value="TIP49_P-loop"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11093">
        <property type="entry name" value="RUVB-RELATED REPTIN AND PONTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06068">
        <property type="entry name" value="TIP49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17856">
        <property type="entry name" value="TIP49_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 12 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 12 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="8 12" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="78"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="476"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="476"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="489"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1748239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="500" mass="55038" checksum="9C56B59F4DBF4366" modified="2024-05-29" version="1">MSGIKLSGDSSGTTTTGGMTVREMTRLERIGAHSHIRGLGLDDGLQPRKGGSQGMVGQAKARKAVGVIYRMINEGKIGGRAILLAGKPGTGKTAIAMGLAHQLGENTPFTTMSGSEVFSLEMSKTEALTQAMRKSIGVQILEETEVMEGEVVEIQIDTSFASGDNKPGGKKGGMEKTGRLTLCTTDMETVYDLGTKMIDALSKEKVTAGDVITIDKASGKITKLGRSFSRSRDYDAMGSQTRFVQCPEGELQKRKEVVHNVSLHEIDVINSRQQGFLALFAGDTGEIKSEVREQIDAKVVEWKEEGRAKIIPGVLFIDEVHMLDMECFSFLNRALESDMAPVLVIATNRGITNIRGTEYKSPHGIPLDLLDRLMIVSTDPYTHDEILKILSVRCEEEDVEMADDALELLARIGTETSLRYAIQMVITASLAAEKRKSAQVEIEDIKRVYKLFVDVKRSTQYLMEYNKEYMYNELDDSDEYAVDNGDEEADKKEDSMETSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKM9</accession>
    <name>A0AAD8YKM9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase, FkbM family</fullName>
            <ecNumber evidence="3">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002366</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKM9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053202">
        <property type="entry name" value="EGF_Rcpt_Signaling_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34009:SF3">
        <property type="entry name" value="METHYLTRANSFERASE FKBM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34009">
        <property type="entry name" value="PROTEIN STAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042255493" evidence="1">
        <location>
            <begin position="28"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase FkbM" evidence="2">
        <location>
            <begin position="98"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="289" mass="33118" checksum="6E997BA804FC7DDF" modified="2024-05-29" version="1">MSDNKRRTSIAIVAILSTLLMLHQLRNQDPTFAHTISETSKSSASQLLNNTAPAWKTAARACERPVILEERWYKSQSREDRALEKWFKDICHGTYMEIGGLDGVRFSNSYVYNKGLNWTGVLVEASPRNYQQLVRNRPNEIANVHAGVCEKEMDLHWIESHLAVGGFQEFADPEFQKRWWSEGQIQNAQVIKCHTLEQILLDKVGPGFYFDFFSLDVEGAELSVLRSINFDLVGFGVIVMEADEHNATKNIAARELLESNGYMYLEDKFRSSWFLNQDFGAIYKDLIHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YL04</accession>
    <name>A0AAD8YL04_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_001911</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YL04"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18572">
        <property type="entry name" value="ABC_6TM_TAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000215">
        <property type="entry name" value="ABC transporter B family member 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000218">
        <property type="entry name" value="Multidrug ABC transporter ATP-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF1">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="286"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="370"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="827"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="868"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="906"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="944"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="978"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1004"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1138"/>
            <end position="1160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1172"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="149"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="476"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="75"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1747948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1201" mass="130160" checksum="B219712C51519FBE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YL52</accession>
    <name>A0AAD8YL52_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_001255</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YL52"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45641:SF19">
        <property type="entry name" value="NEPHROCYSTIN-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45641">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041963595" evidence="4">
        <location>
            <begin position="29"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="460"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="465"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1747292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="973" mass="109534" checksum="7DB8CEBD703AC27D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YM85</accession>
    <name>A0AAD8YM85_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001825</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YM85"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033579">
        <property type="entry name" value="TMEM128"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31134">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31134:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20479">
        <property type="entry name" value="TMEM128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="167" mass="18629" checksum="1E0CC12CF853795B" modified="2024-05-29" version="1">MSSYRRVATADAAASSAPSNNDEAYGKRTRSERISDKIHALAWVVVAYCTASYTHFFPTLFSDDRIIRPIFNISMALFSINVTLTLYLTIYLPCKFPRSPTFNVSASSLEFWGAYCPRVIPIMTVCGVIGSFLLVRSCVGIWGFLTPLVIAVIAMGMFFSLHFIPWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMM3</accession>
    <name>A0AAD8YMM3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Elongin-C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_000726</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMM3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039948">
        <property type="entry name" value="ELC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20648">
        <property type="entry name" value="ELONGIN-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1748787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="60" mass="6993" checksum="F63B9718D241AE34" modified="2024-05-29" version="1">MRAMLEGNFRESEESVIRFPDISDSALEKVVRYLHYKDRHASSTARIPEFPIEPEEVSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMP9</accession>
    <name>A0AAD8YMP9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">cAMP-dependent protein kinase</fullName>
            <ecNumber evidence="13">2.7.11.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_000771</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.11" evidence="13"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMP9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030553">
        <property type="term" value="F:cGMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000210">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001194">
        <property type="entry name" value="cDENN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043153">
        <property type="entry name" value="DENN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037516">
        <property type="entry name" value="Tripartite_DENN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF147">
        <property type="entry name" value="CGMP-DEPENDENT SERINE_THREONIN PROTEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02141">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00799">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50211">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0140">cGMP</keyword>
    <keyword evidence="7" id="KW-0142">cGMP-binding</keyword>
    <keyword evidence="5 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="11">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="101"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="UDENN" evidence="12">
        <location>
            <begin position="577"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="378"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="484"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="724"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="770"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="384"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="488"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1748832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1242" mass="139467" checksum="C638849AB135096C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMZ1</accession>
    <name>A0AAD8YMZ1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BZIP transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000224</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMZ1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="2">
        <location>
            <begin position="21"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="131"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="192"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="218" mass="22932" checksum="7AFEAC5F94CCD27D" modified="2024-05-29" version="1">MSDNAADDASISSGGGEETKDGKRKERLEQNRISARESRKRKKNMIEELQRTVITLSRENKELNERNDTLRRELVEIGTNNPGVVNIQALMSCTGSTSDAAATAAATAAALPEGIPSGNTSGGAATGGNTNGADNNAAAAPSANPQAAQNQQQVQNAIQQQQQALMQQMFAMNPALMGGMMGMSGMMGGMGLQQPQPQQSDQQQQQQQQAPAPANPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMZ2</accession>
    <name>A0AAD8YMZ2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMZ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="929" mass="102195" checksum="9F6FB6F0206D8DB6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YNI7</accession>
    <name>A0AAD8YNI7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Emp24/gp25L/p24 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_000489</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YNI7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042264731" evidence="8">
        <location>
            <begin position="22"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="9">
        <location>
            <begin position="25"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1748550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="221" mass="24997" checksum="FED0722BE1667B20" modified="2024-05-29" version="1">MRLPIILQILLFAVLNGYYIAVEGAFSATVESGEEHCYNVIAPAGVQSVIHGNFDILDDDESPDPIGVVLYDSKMTPVWRSERQAQEGTFSITGEGKYELCIQNGNMGSDDYVAPKDGIDREVGFAIRVVPPQRGIEGEAGPDDRLTSHLIELSEKLMEGLDTMTDHQEYMRERENRHAMLADSTFNRVKEWTFLEAIVLVLISFGQVLYLKKFFEQRRYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3R4</accession>
    <name>A0AAD9D3R4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016723</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000063">
        <property type="protein sequence ID" value="KAK1732582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3R4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="MAPEG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="122" mass="13683" checksum="8E4A735251208001" modified="2024-05-29" version="1">MATIELTAEHGKCIAILILLWLQQQLVFAIAVAFARKKSGIDAPTLYPRDSEIKKLNLSEKDVDSYMCTFYAGIVVLMGRMVTALGYYRGASKRVAGGWFHFGEYYVVYLAGKFAYKLINEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3Z0</accession>
    <name>A0AAD9D3Z0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sel1-like repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_017029</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000077">
        <property type="protein sequence ID" value="KAK1732254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3Z0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="99"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="157"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="166"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="519" mass="58178" checksum="517C1A54BE62FFBB" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4N8</accession>
    <name>A0AAD9D4N8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Purple acid phosphatase</fullName>
            <ecNumber evidence="6">3.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_016407</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a phosphate monoester + H2O = an alcohol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:67140"/>
            <dbReference type="EC" id="3.1.3.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.2" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4N8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00839">
        <property type="entry name" value="MPP_PAPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.380">
        <property type="entry name" value="Purple acid phosphatase-like, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041792">
        <property type="entry name" value="MPP_PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025733">
        <property type="entry name" value="PAPs_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015914">
        <property type="entry name" value="PAPs_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008963">
        <property type="entry name" value="Purple_acid_Pase-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45778:SF7">
        <property type="entry name" value="PURPLE ACID PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45778">
        <property type="entry name" value="PURPLE ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14008">
        <property type="entry name" value="Metallophos_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16656">
        <property type="entry name" value="Pur_ac_phosph_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49363">
        <property type="entry name" value="Purple acid phosphatase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Purple acid phosphatase N-terminal" evidence="11">
        <location>
            <begin position="109"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="9">
        <location>
            <begin position="256"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="Purple acid phosphatase C-terminal" evidence="10">
        <location>
            <begin position="484"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1732869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="552" mass="60533" checksum="3A0AFC85EAD69A58" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4Z5</accession>
    <name>A0AAD9D4Z5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016233</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000054">
        <property type="protein sequence ID" value="KAK1733095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4Z5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="390" mass="45052" checksum="01BE52C1C1B64CE6" modified="2024-05-29" version="1">MRTERSKYATEALLSFSSKVRRRATDIEHSTNYQQLMDDDDSSPLRPAGNKFVRKKSNNFRWKTIVSCADTAAERFVVHNSRTDEESRDDDHKYLLGGGEDRCQVMETFTSSSEEDKPYNRTATTKLLLLPGLVDFGGSSRQGPLTLQELGFKPLKKTVHFSTVDVKMYRWDRKYDKDVYYTKNELSNISKRRHEDAVKLRKERLFSGQHTKDLTPTLLSFIFDPNDDIYKRATSRGVEHFIYPELRRELMRKQKEARAEVLKYVRSNPFDPDGSKLRELSEQYTRWARELAVDKAKCYAQNNALFLSKKEVMRQSVVGSSTGINRSIVKKEATILEFKKVKISLDDVEAALGKTSIHKYSDRKDESENTATESNNMASPQQDFCTLVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5C8</accession>
    <name>A0AAD9D5C8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Circumsporozoite protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_015762</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Essential sporozoite protein. In the mosquito vector, required for sporozoite development in the oocyst, migration through the vector hemolymph and entry into the vector salivary glands. In the vertebrate host, required for sporozoite migration through the host dermis and infection of host hepatocytes. Binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes.</text>
    </comment>
    <comment type="function">
        <text evidence="5">In the vertebrate host, binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes and is required for sporozoite invasion of the host hepatocytes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the plasmodium circumsporozoite protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000047">
        <property type="protein sequence ID" value="KAK1733589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5C8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051860">
        <property type="entry name" value="Plasmodium_CSP_Invasion"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44826">
        <property type="entry name" value="SPORE COAT PROTEIN SP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44826:SF3">
        <property type="entry name" value="SPORE COAT PROTEIN SP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0748">Sporozoite</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="568"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="570"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="585"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="603"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00033726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00045806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1733589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="826" mass="87503" checksum="3ACA69377BCB39C4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D610</accession>
    <name>A0AAD9D610_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D610"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1735416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="186" mass="21406" checksum="F05B804085532D73" modified="2024-05-29" version="1">MERRIHSSFISWGKQVSAKGTNRQWTSTLSCVQADLRIQVSSLWLSPEVLLKKFESNFRSMCSDGSVLAAYLYNNLEESGSGMLNMFLDGKFKKGVDKNVPYKSASELKGLFTKDIEETFKNGFARVEVKNHFDKHFCDFTIQQFLISLGYHSFDELKEEERSLIYKCGRFPVWDEITEEPVSVSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6W4</accession>
    <name>A0AAD9D6W4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ATP-dependent zinc metalloprotease, FtsH family</fullName>
            <ecNumber evidence="9">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_012976</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6W4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000001">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076:SF97">
        <property type="entry name" value="ATP-DEPENDENT ZINC METALLOPROTEASE YME1L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076">
        <property type="entry name" value="METALLOPROTEASE M41 FTSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="8">
        <location>
            <begin position="462"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="74"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="120"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="319"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="130"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="319"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1736376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="794" mass="88083" checksum="5D8F4BA4B0FC65AA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D779</accession>
    <name>A0AAD9D779_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">15-cis-phytoene desaturase, chloroplastic/chromoplastic</fullName>
            <ecNumber evidence="5">1.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Phytoene dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Phytoene desaturase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_013628</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2 a plastoquinone + 15-cis-phytoene = 9,9',15-tri-cis-zeta-carotene + 2 a plastoquinol</text>
            <dbReference type="Rhea" id="RHEA:30287"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:27787"/>
            <dbReference type="ChEBI" id="CHEBI:48717"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
            <dbReference type="EC" id="1.3.5.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carotenoid biosynthesis; lycopene biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chromoplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the carotenoid/retinoid oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.5" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D779"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016166">
        <property type="term" value="F:phytoene dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000091">
        <property type="entry name" value="15-cis-phytoene desaturase, chloroplastic/chromoplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050464">
        <property type="entry name" value="Zeta_carotene_desat/Oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923:SF45">
        <property type="entry name" value="15-CIS-PHYTOENE DESATURASE, CHLOROPLASTIC_CHROMOPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0957">Chromoplast</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-0934">Plastid</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="14">
        <location>
            <begin position="15"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1735465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="427" mass="46756" checksum="CA2A24590A232879" modified="2024-05-29" version="1">MTFAMQELPGEFTSFEFPAGVPAPFNMAAAILGNTKMLTLEEKIKMVPGLLPMLLEGQSFIDAQDELSVLEFMIKYGMPDRINEEIFIAMGKALDFIDPDLLSMTVVLTAMNRFINEADGSQTAFLDGNPTKRFCEPIKNFVESTGGEVVCSSPVTQIHLNDDNTVKSLQLKDGTQVEADYYVSAVPVDVFKRLVPTQWSTDPFFRQIDELEGIPVINIQMWFDRKLNSVDGLCFSRSSLLSVYADMSNCCAEYASETSMLELVFAPCCPEAGSPINWIAKPDSEIIDAALKELARLFPTEIGDDAPEHKKAKLTKSTVVRVPRSVYAAVPGRNKFRPSQQTPIDNFILAGDYASQKYLGSMEGAVLSGKLAAEVICDKEMNRDSKGLKDVHSSVLGKEFSSKDPVGIVGSGATVYGGGKQGNFENP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7Y2</accession>
    <name>A0AAD9D7Y2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MRG family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_013169</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7Y2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000123">
        <property type="term" value="C:histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.30">
        <property type="entry name" value="MRG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008676">
        <property type="entry name" value="MRG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038217">
        <property type="entry name" value="MRG_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026541">
        <property type="entry name" value="MRG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053820">
        <property type="entry name" value="MSL3_chromo-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10880">
        <property type="entry name" value="MORTALITY FACTOR 4-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10880:SF15">
        <property type="entry name" value="MSL COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05712">
        <property type="entry name" value="MRG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22732">
        <property type="entry name" value="MSL3_chromo-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51640">
        <property type="entry name" value="MRG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="MSL3 chromodomain-like" evidence="9">
        <location>
            <begin position="107"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="MRG" evidence="8">
        <location>
            <begin position="235"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="138"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF22732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1736033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="436" mass="49525" checksum="DFD64E247AFBCE05" modified="2024-05-29" version="1">MADTAATNDLPQESGEEAADYSGPKYHAQQKVLCIDTNNNTSDDAFAPLYEAVIRKSELKYIDPTTQKILPNRKRGRGRGRVGAATVDALDQNTNDLGTGLLQEWCHHVHFNGWNSRWDRWVTERDIFENTIENRKRLSENSGKVARSQPKQKEETKKRKREAATTADNDAESSSSPLNRNLQLITRACELPFTLQTVLCDDRDNIAVKVHPPPILSASCSSKQQQRRNNKKAITMLHVIPAPTSIVDLMGQYVQAKKQEDLETFANYHRRLQRDLSGNSSCSDGGVGEESSMDVILTKEDLKMNKKKRKEFALSILALVDASLPLFLLYAEERDQFTKLMAQFAKEDDKQSDNDHQTPKRQPSHLYPAEYLLRLFVKIPYLLSEFDLKKNNPASILLADEKTQDFARFLSELIVFIQTRVDECFAGNYQALEVDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D947</accession>
    <name>A0AAD9D947_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">SET domain-containing protein</fullName>
            <ecNumber evidence="11">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_012115</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="11"/>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20404">
        <property type="entry name" value="Tudor_Agenet_AtEML-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006560">
        <property type="entry name" value="AWS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050777">
        <property type="entry name" value="SET2_Histone-Lys_MeTrsfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22884">
        <property type="entry name" value="SET DOMAIN PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00570">
        <property type="entry name" value="AWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="9">
        <location>
            <begin position="461"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="10">
        <location>
            <begin position="584"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="90"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="126"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="138"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="180"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="224"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="246"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1737248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1341" mass="150997" checksum="08F395D87E2EBAFF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9F2</accession>
    <name>A0AAD9D9F2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011456</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9F2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042284428" evidence="2">
        <location>
            <begin position="23"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="165" mass="16914" checksum="F08B41C65E97E750" modified="2024-05-29" version="1">MKIYIALFTTLIAAGHFTNVSAADAAASVDGASHPHLRALADVDVACRSGCNNDNHCSGSVCSVNGGSDCSGVCCSATECNANGDGCPSGAKCDTGYDGSTSGCHGCLISDNGFVPHSELKQAASTPVDVDVIEEVEEEEEVDSIQDHEDDVEASSLRASILKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DA37</accession>
    <name>A0AAD9DA37_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial import inner membrane translocase subunit TIM22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010909</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DA37"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="244" mass="26361" checksum="E5A888070FE6F203" modified="2024-05-29" version="1">MSSWDRSRTIPWSRAIPVAPATASGDMEDVDLLKERIWRDLSWEAAQEEKERKEQQKLAAAVAADQNGESSASSTLANTTDAQHIMQQSSSSITSTTTDSDVEKNILGFVGRPYLTSDLLKNAAFGATIGSITGMCFGFMDSIRSASSSTVLKSASRSAQGKFVFQGTYRSGMFFGAFFGVFHTAKYATRVLVDPGDAGEICAGSVAALGGVMAKREWRVSMPYAVMLVAMDTFHVFMREDGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAA6</accession>
    <name>A0AAD9DAA6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008956</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAA6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46546">
        <property type="entry name" value="SHEWANELLA-LIKE PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46546:SF4">
        <property type="entry name" value="SHEWANELLA-LIKE PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="192" mass="20675" checksum="0E7B587642A289EA" modified="2024-05-29" version="1">MASHLSPGNSINEGQKMYGGVTRLNQQARDWIVTAHHGENNNWGEYNTVEEVISAAQNRAKVASKTMPDCLGGGIGASSPVWMRDYSKPNDAEPSEPLAKQKIRAALAEAGSDVQRMVMGHTPQYKINSALDSMAWRIDVGASQGVMGGTPEVLEIIHMGGDNDEDIVSVLTVDGKRVDGSDRAVFDSSIMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAC2</accession>
    <name>A0AAD9DAC2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF285 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009016</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAC2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005046">
        <property type="entry name" value="DUF285"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011889">
        <property type="entry name" value="Liste_lipo_26"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02167">
        <property type="entry name" value="Liste_lipo_26"/>
        <property type="match status" value="18"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03382">
        <property type="entry name" value="DUF285"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="804" mass="89566" checksum="E040A28727741BA0" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAD8</accession>
    <name>A0AAD9DAD8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008987</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAD8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="129" mass="14871" checksum="DA1DE69425E7EDD6" modified="2024-05-29" version="1">MIRPTTTLLLRKLITLPPLSPTHTSSRILRRLVPTSSHVIEYQPILILQCSPDLIADPAMRKSDGHEPRMLLESLEEGKVVWREDVGEDDGQWYDVGMVIGEIVEDDEEEESEDVEEWTWQAYLDEPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAG9</accession>
    <name>A0AAD9DAG9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010628</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAG9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="194"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="330" mass="35015" checksum="FB0F671AC430E742" modified="2024-05-29" version="1">MPSPAGIPPASPSGRGATSYVRCVGGGVGDTAAPAAAGNKVDTPVPAVMAAGNAEKNNARTSTIVHQFGMLKLPPPANNGKYTNIEVIDLVITHNASDVVKAIHASAYRPKKAALYRMLSKNKPFDKDTLVLLLKEVYDGTEEWDDRVTQITKYTGQSERQIRRIIGLSKEYDSDEEDEEVTALCSNQSINNGTPSSTSLTSSTPSTISTSPSSTSLTPSTTSTTSTSPASAKSTPHSYGSLSCTPSQMRSQSASDGAKKRKSPDISSDSNDDATDLPSLITNRILSNSDIKRPTPNQTEAYDLNRAVQTFRASIEKDGVTSDILTHFNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBZ4</accession>
    <name>A0AAD9DBZ4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
            <ecNumber evidence="2">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBZ4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF154">
        <property type="entry name" value="GRIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042144698" evidence="1">
        <location>
            <begin position="16"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="450" mass="51709" checksum="A9F3BB21165A3B30" modified="2024-05-29" version="1">MKFILLLSILDAAAAFTSPARLITTTKHPNHDHRLYSTYDTDSETTLIDIDEEAPRDIPSMEAWSYEMGAQRTDGFTLTTDDGGYNVYAMTNVDLPTGSPILTIPEHMILSSNKAMAELRTSDMSEAEKIVKSVNAESEFRHYYLMLKLLVEYEKGMESPWYQWMNSLPRYYTNAASMTPFCCLCLPSLMRKLTVQERGYLQRLGVSSIKMVPYLNEDTKYDVDLCTWVYQIVYTRSFETADGDLKIVPLADMFNHGAYPEVESSYDEEGNYYAYTTYDVPAGSPLRMSYGDPTNPSYLFARYGFLDESTEATFCKIIPEHINKDMEELGYAHNRMLFYKDGNVSEEVWDILLFQHVSSTKIGDKRALMEAHRSGDYATKQMLHEKYYENTSAMLLEHLESFLEQLEKLSSKAGERQTELGDHPRLPLILAHNEFVKQTFLAVRMQNFGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCC0</accession>
    <name>A0AAD9DCC0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006896</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCC0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="153" mass="16767" checksum="92680312A07A5D61" modified="2024-05-29" version="1">MALIPDTDQAPGYCSIATAPLTTEQISRIVSCATSGNETAGITVITEKELGLKGQRKLHILDTKERTLVVEYAGVRKAKFVKKDLERFQAMMDEYEGSEKDVLNILLLKEDGTICRRNTLPALHRQGVVVMRCPASDTDSDSDDSSTSSDDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCC4</accession>
    <name>A0AAD9DCC4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_006762</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCC4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1742197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="231" mass="25993" checksum="4149FEACD6E0F5DD" modified="2024-05-29" version="1">MASLRQHQELDNTNISAATLVSVKGATAIADEETDTVGHCAILRPKIAPQEDNAGKIIVHDSMNRSSNSSHSTTTMSTSISSKMSSMVDDSHRSMKRNVCFSNLEIRSYDITLGDSPTMRGPPISLGWKYDPKETETYEVDAYEQHRNPRRTKIELVMPPAYREDRMQDAGFSRFEMKQVMEEAQKVAKQRKKNMQTITNKRSLGIDEILGKANDTRAKIISKLGRRRSAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DD27</accession>
    <name>A0AAD9DD27_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycerophosphocholine acyltransferase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_006469</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GPC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DD27"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006656">
        <property type="term" value="P:phosphatidylcholine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021261">
        <property type="entry name" value="GPCAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31201:SF1">
        <property type="entry name" value="GLYCEROPHOSPHOCHOLINE ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31201">
        <property type="entry name" value="OS01G0585100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10998">
        <property type="entry name" value="DUF2838"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="154"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="194"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1742872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="394" mass="45063" checksum="7070C9A49E46641D" modified="2024-05-29" version="1">MSSEQSSTDSTADGVPAAESEEALDFRSSMIMTQDWNLDVDSDELDDSPATVTDARQTFQNLVRSAIKYDTFKKGEADTVRRIIEHIELVSLKKSAEGFNRVNFSVGVLNCFFICWVLGAYPEYIWLLYLIEAVYFIPRKFYNMWRAKPLNQAFYYLDFCWFTNFFAMAYFAIIVISGIFGFNDDIQNGIREVIFKAALGVFCGVLVCANLALPFVACLFHDVNTMTGLFIHLMPPVVMYTFVWYNDRIVEAWPNLFNLSYLEDGLTYYGGTDSIASCSTAFYFTWWVIYVCFMLGGGGIDLPKKFKPDGSPANPRYDTVFHSTMRDGVCILIGKFFRGRSKADSLTLMETNMFDKIDFCLYMVFHMIASLSAIFLSGYLCFKSIKRTRTLHRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DE53</accession>
    <name>A0AAD9DE53_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004844</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DE53"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="451"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="491"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="556"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="632"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="704"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="889"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1023"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="251"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="516"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="632"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="706"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="734"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="765"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="807"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="824"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="838"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="895"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1042"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1069"/>
            <end position="1081"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1081" mass="119594" checksum="B17AC4885DF10B2D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DER8</accession>
    <name>A0AAD9DER8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DER8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041918034" evidence="2">
        <location>
            <begin position="16"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="415" mass="45957" checksum="4FF9F9CEA7CD55EA" modified="2024-05-29" version="1">MKIALATALIGVTSATTSSNNPFAPKVTPNNADSKRIGRLLSSATPLRQLDGGSSGSSAIDISKYSLRFEKCSTVKQYNSNNNYQESDTVLSAKRFVIFRLCPNHSCGSCDENYGEYLIDMESYLDAMLQYKYEEQTEYCTACETCYTKASQANNDMGAYYDDAVEGQQEDDDGCGSFNLDSCYKECLNIANMESNGYVDAADYVGCVKVYENENKGLAYWAGATCNANGSRIKIGLFTDEDCNNQDDSANTELYMKNDNGYNVKLSYHLLKHTFVNGYNNCITSCADYEDGSDYAQTAEVCDTLYDSSAKCETSHAFNYRTSENSQNWMEEMTACDFIEQVNYGTYDESGEIVVTGGRMIIQRATSSGAQRFFLTFFVWGTIFMSAYVALLYHKIMKGQKSLLSAHAKDGAALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DF58</accession>
    <name>A0AAD9DF58_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006156</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DF58"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="114"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="248" mass="27929" checksum="BDDEA4E676011BC2" modified="2024-05-29" version="1">MSQILPQKRSAATDRPDPPSSTTTTNSQRYTKLLSVLTKSLQQSRDKVESEAAHLIKEIYGDMTSLFTTGEDDDGVTQLVDLLLGKLDTVHDRFNVEKSSSSSNMTKLESILEEQQIQQLLQRVETAIERVEMDEQNFQQDEAADKQSAEEAVKQAHTLRVDSVAGKLRKMTADQFAGYHSHKKKEEYFESLQKELGEVTKENDEMEAALVEKWEEWQKNLGDVKGALGVLQQLGSVEEEEGKGPRDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DF74</accession>
    <name>A0AAD9DF74_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_003345</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DF74"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="225"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1745421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="465" mass="52647" checksum="90BC775F09DF5143" modified="2024-05-29" version="1">MILIDHEAATASFTVGCTVILQNLVGGAQYNGKRAVVNSPKSSAGRQQVRIIDDDKVIAVKPVNLRYEPREVSSLTADEMRRVLICSWKKTESQVEGVDTNSLAAMVSKYFSCPAELATILAIKKRQQQQEAIRFGAVNILMDETDEYLADLMSNLKTSPNLRRLYVGPHSESCTNEEMDYIITRQFYYARHPGEILCISGDRMDPQRILHLYELNKVKDIGNRCRFCNKEDTSEREFAECASCGLVTYCSKGCQKADWKRHKPNCIKVSNNEKTKQRGKFKKRMDRFMRLYGPLVRSALLDHIAILAKKVGAGFDEEKYFISVLLRDLPIVSATRPYLSIDKTILDDKVSNQNGETKSLLKKSRKAQPASLLTRNHLFHWSFCYEGHDDMAFNFIMPVPKDEFKRLLRCTMDELSASMLCKINTINAVAMGEDPNLYKAIKKAAESKEKEFKSTANSNGVSGNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFG7</accession>
    <name>A0AAD9DFG7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ C-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005462</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFG7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044713">
        <property type="entry name" value="DNJA1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43888">
        <property type="entry name" value="DNAJ-LIKE-2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042127752" evidence="1">
        <location>
            <begin position="33"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="16"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="277" mass="31262" checksum="DC2588BCF1D810CE" modified="2024-05-29" version="1">MPSLRQSSTRTMLTQFLLTLLLLHTQIHRITAAEDFYKLLGISRKATQKKSKRPTAEKFAEIAYAYEVLTDEEKKNIYDRHGEEGLKQHEQRQGQGGGHGGFDDIFSHFGFGGGFPGGGGGRQQREQSTPNINIPLRVSLKQLYLGDTIEVEYVRQTLCVNWQECMKANQECQGPGVKVRMQQIAPGFVQQTQSEKIDLTIDLQKGMYPGEPITFDGVADEKPGVNESGDLNFVITQEKHEYYHRDGDHLYVTMEIPLVDALTGFKHEFEHLDGTNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFU0</accession>
    <name>A0AAD9DFU0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFU0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="369" mass="41351" checksum="DC58E46BD29D93A7" modified="2024-05-29" version="1">MRINKSKRISGNVCSGRYSLPLAVAAAVICTYLVTSHFDFKEQKKSNNNLRQTATATATSSNALFGVVVPQGRAVAMPSVRISAEESETIKRNIYGGEGDKAHLGGFTSFDPHGVSPTLWKHMVEWLGVKSLLDVGCGIGTSTSWFVTHGLEYVQCVEGSHDAVTKSLLPKLPQWKEDMIVEHDFSRGPWWPDRTVDVAWSVEFLEHVGRNYQHNYLTAFRKAALIFVTHSNWGGWHHVEVHDEKWWRARMEMMGFVFSQDLTNIMTGKASEDKGRNDIVAAMESDKQYSVGQHIWSTLQVYINPLVASLPEHAHLLAEHGCYTSEKGIECGTTGNNVESVLPDNFKPLKLTDDMDKEWSELVKDLELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGX4</accession>
    <name>A0AAD9DGX4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004504</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGX4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="64" mass="7462" checksum="99FDC59DD68997EC" modified="2024-05-29" version="1">MQQKEEAFISMPGYSGQVNDDQADTAGNWMSAKFKCKQHADNDTRTLDKLEIPRRGWWRWSQDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHG7</accession>
    <name>A0AAD9DHG7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_001934</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHG7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45641:SF19">
        <property type="entry name" value="NEPHROCYSTIN-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45641">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="211"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="330"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1747971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="598" mass="67746" checksum="7DA4F3ABEBAC7195" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHM9</accession>
    <name>A0AAD9DHM9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tetratricopeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_001500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHM9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904:SF513">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904">
        <property type="entry name" value="TPR REPEAT CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="32"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="156"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="304"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="347"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="156"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="198"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="216"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1747537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="404" mass="46555" checksum="BBD493757098B5CA" modified="2024-05-29" version="1">MSSSDQAATNGSGGSSGNKEADDTREEWEIRRDELKATGDGHFRSKAYQPAIQTYADALQLDPTNHIILSNKSAAHLANGEKSKALHDARKCVKHSDGKWSKGHTRLAAAMMSLGRYGEAADAYSTVLNELDPNNEVAKRGLEDCRKKEQQLREEKERELRKMQEVLDQQKKAEKEAQEEKETETKNDNKVEKATEQPKPTKSTADNDSGEEPTNRIKTQMNDLGTSQSQIDRLLQVNYEWKNLNPFYVSALSLLVHPDKCLDDPVRAKTAFEQVRKAMNQMNDVDKRKHVRALIDEGMKQGKRDWKEECSKSSNVHPDNKEGLAQAQSKATMKIFAEIEQKRREIERRKRKFEQRERAQEDDEKKKETDERRFHNEWREGERVDKRVGNWRDFQVDGKKKRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHS1</accession>
    <name>A0AAD9DHS1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Vacuolar protein sorting-associated protein 54</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_000225</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000938">
        <property type="term" value="C:GARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000383">
        <property type="entry name" value="Leucine-rich repeat receptor protein kinase EMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039745">
        <property type="entry name" value="Vps54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012501">
        <property type="entry name" value="Vps54_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12965">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12965:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07928">
        <property type="entry name" value="Vps54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 54 C-terminal" evidence="11">
        <location>
            <begin position="2122"/>
            <end position="2250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="326"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1091"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1146"/>
            <end position="1267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1286"/>
            <end position="1341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1587"/>
            <end position="1643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="2392"/>
            <end position="2563"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1680"/>
            <end position="1707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="47"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="64"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="87"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="127"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="158"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="351"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1146"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1172"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1186"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1221"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1233"/>
            <end position="1261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1292"/>
            <end position="1306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1615"/>
            <end position="1628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="2395"/>
            <end position="2406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="2449"/>
            <end position="2491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="2538"/>
            <end position="2548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1748286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2563" mass="278315" checksum="977863DD93CBBCB0" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIN5</accession>
    <name>A0AAD9DIN5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin domain-containing protein</fullName>
            <ecNumber evidence="2">1.8.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002419</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.8" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIN5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031397">
        <property type="term" value="P:negative regulation of protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030178">
        <property type="term" value="P:negative regulation of Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46472">
        <property type="entry name" value="NUCLEOREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46472:SF1">
        <property type="entry name" value="NUCLEOREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13905">
        <property type="entry name" value="Thioredoxin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="30"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="189" mass="20361" checksum="D4FB503B8F1F2F54" modified="2024-05-29" version="1">MIVPAACFAFLISTRHSSPLTRCASRTRMTSSLSALPNLNKSDGTGASIDDISEQVKGKHVALYFAAGWCPMCSSFEPSLMQFREAANSSGKEVEIIYVPSDRQAADVVKRTSSMNMLSVPIGEEADAMKRKYKIWAGAESLKLGMGRRSGVPALVVLDKSGDEVHFLAAESKGSKALGDWPLDDSGLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIY4</accession>
    <name>A0AAD9DIY4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001832</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIY4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="490" mass="54346" checksum="66C22C3763C91D85" modified="2024-05-29" version="1">MLGIVPGPNAVFEWTQEWIQTLNQADEDKPPTFNVVESPPGHRHKRRDSWDSHGESILRNGYQKKRSVSWSKTIQVQTFQDSESRDDVPESESEESESDESYDDLQINQSNTMDDGGAENRDFDAVGDDVADIKKTDIVCEDAAYNTVTENTDAVNAEVADKRESGDGNPNEKRILPPSASEESEDVFAQIEVSYTGASENAPYKISTDQSNEDVFDLVAASSTISEFTMEGITAPTDHEPITHSSEKVKPSNIFTPVLLPSNFRLENRLDTTDSGSFCTLSEDDRSLISNMDETASLVARRAASDDESIVNLRRRKEEYDDTKQREIDGVLGHLGINLPLPSMKNFWSAMLANEVLCTSEAASFDMKGSNAEGDYTEVHRTGSISEASIEDLLPIKKSMSDGDGSDDVDSDMATLSKDVSMSQDELGNAWHIQNAKKKKSKFRRFSLNRKKTAGFNEVPSNTVPSIKKRGLFNRRRKKSKAAAPQLLVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJ71</accession>
    <name>A0AAD9DJ71_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Yip1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000063</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJ71"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039765">
        <property type="entry name" value="Yip5/YIPF1/YIPF2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12822">
        <property type="entry name" value="PROTEIN YIPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12822:SF2">
        <property type="entry name" value="PROTEIN YIPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="313"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="372"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="414"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="221"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="440" mass="48082" checksum="EDC0630DEFFD4F82" modified="2024-05-29" version="1">MSSHFKRDDLFLLDWPRSSPPKRTCCSNTIIAVEVNNNIMSSPPENPFSSGDTDDNNRFDAFQLSPDKTSSRSSLPSLQSIQAAQQQQQMQQQQRAAPSSSQQQQQSTFDNLPSPEELQGPISSTTNNNNDWIPQPSSTANNNINNNINDNQQSSSSILPKFLTCGGALSIESLRPYFDVDTADIILRMKSSIKYCNVPDGFRNEVLYSDNAMRLSAFRESTAAGGEGGETTTAGASTSSSSEVTSVGNVGGGEGKGPDLYGPTWITMTLVFFLAVTSNLSLYFHHSGKQYQSLVDEGGVAAEEEWDYDINQLLHATWILYSFSFLLPMGLYLMFRLMGIISFSVVDLICFYGYSLVAYIPTTWICVAPVSWLQWLSLCISTVVSGMLVLRNVTGPILESAGGGGGVGQGKSGGLIMAVIGCHFIFFLVMKLAFYHHVHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DK34</accession>
    <name>A0AAD9DK34_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000242</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DK34"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="347" mass="37623" checksum="F91246DDAAF8F69A" modified="2024-05-29" version="1">MSRQLMMVHNIAIVWSIMLPLGLLPLGCLSFHIIQPHVTSKSSTSSSSCLYSTKSSADTEYVSPFNLEEFNNDSSLSNNDNNAVEIWLDLRGSISPSTALELWDLECTDANYNNDGDGGGKKSGAPFTKCLVSPSDKSNSKSEKQMQLQNNIQVLVDNGTNNNHNEQTTESTSSSWGKVLPLQTNTQSMPILPDPLPAMEIISQGQYIILDTTKGWKKVEEEQRLSYLLPLAELISSGATTGGENGGGSGGIGFTCLTKNEVVKVAMWIQSITNNNRSGDGGGGQNVRVKTLENGLVIPDYDDDDVTSDLQKQFGSSRQARLQYAIVVPYDVGLLKTASMLLLNEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DKK1</accession>
    <name>A0AAD9DKK1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_000737</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DKK1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1748798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="129" mass="15015" checksum="9FE6B0352B445679" modified="2024-05-29" version="1">MRVAHRNEYDEDVDVAIVLEENSAWTHTAASDFDIKNGRKVAVEFDGPHHLPLTPEFWVTRFEISFAKTQGLDCCQDTYYEFDKIPQFASMEIQRYLQRALKTHDKIEFSGVDVSEYKAMPSSRTSRFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-12-02" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6U3WLY9</accession>
    <name>A0A6U3WLY9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mesencephalic astrocyte-derived neurotrophic factor homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">MANF/CDNF-like protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_016319</name>
        <name evidence="11" type="ORF">SMAR0320_LOCUS13756</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ARMET family.</text>
    </comment>
    <dbReference type="EMBL" id="HBGZ01019221">
        <property type="protein sequence ID" value="CAD9610987.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000055">
        <property type="protein sequence ID" value="KAK1732988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6U3WLY9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.225.10">
        <property type="entry name" value="Saposin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045333">
        <property type="entry name" value="ARMET-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019345">
        <property type="entry name" value="ARMET_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045332">
        <property type="entry name" value="ARMET_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12990">
        <property type="entry name" value="ARMET-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12990:SF5">
        <property type="entry name" value="MESENCEPHALIC ASTROCYTE-DERIVED NEUROTROPHIC FACTOR HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10208">
        <property type="entry name" value="ARMET_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20145">
        <property type="entry name" value="ARMET_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042404965" description="Mesencephalic astrocyte-derived neurotrophic factor homolog" evidence="8">
        <location>
            <begin position="21"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="ARMET N-terminal" evidence="10">
        <location>
            <begin position="27"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="ARMET C-terminal" evidence="9">
        <location>
            <begin position="123"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF20145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CAD9610987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1732988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="169" mass="18631" checksum="77657F2139285B99" modified="2020-12-02" version="1">MKSVSIIAAAAVMLASSVSAASNDPRECEVCMKVMQDVRDAIPKADQTNKPAIEAALGAQCAKDTLSARERKICYYIDPIKRDVAHPFSLGMPVDRLCKRINKSNSEICGVKFPVKTENLEKKDLTKLRVKQLKSILVDRGVECKGCVEKEEFIAMVQNTEHLAGSDEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1H092</accession>
    <name>A0A8K1H092_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">Small ribosomal subunit protein uS12c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 13" type="primary">rps12</name>
        <name evidence="12" type="ORF">QTG54_017159</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="13"/>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2021" name="Front. Plant Sci." volume="0" first="0" last="0">
            <title>Chloroplast Genomes for Five Skeletonema Species: Comparative and Phylogenetic Analysis.</title>
            <authorList>
                <person name="Liu S."/>
                <person name="Xu Q."/>
                <person name="Liu K."/>
                <person name="Zhao Y."/>
                <person name="Chen N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CNS00100</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 9">With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 9">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Plastid</location>
            <location evidence="9">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9 10">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MW679506">
        <property type="protein sequence ID" value="UAM91367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_010200872.1">
        <property type="nucleotide sequence ID" value="NC_058701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1H092"/>
    <dbReference type="GeneID" id="68637991"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03368">
        <property type="entry name" value="Ribosomal_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000001">
        <property type="entry name" value="30S ribosomal protein S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00403_B">
        <property type="entry name" value="Ribosomal_uS12_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_uS12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005679">
        <property type="entry name" value="Ribosomal_uS12_bac"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00981">
        <property type="entry name" value="rpsL_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01034">
        <property type="entry name" value="RIBOSOMALS12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="13" id="KW-0934">Plastid</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 9" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="113"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00040813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1732116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UAM91367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="124" mass="13927" checksum="4DA4FDA866B25555" modified="2022-08-03" version="1">MPTIQQLVRSRRIQINKKTKSPALVNCPQRRGVCTRVYTTTPKKPNSAIRKVARVRLTSGFEVTAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDSGGVKDRTQRRSKYGVKKPKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRB0</accession>
    <name>A0AAD8XRB0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016919</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000068">
        <property type="protein sequence ID" value="KAK1732384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRB0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="486"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="249"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="529" mass="58309" checksum="67A809CB49C0427F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRL1</accession>
    <name>A0AAD8XRL1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_017080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000079">
        <property type="protein sequence ID" value="KAK1732232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRL1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="115" mass="12900" checksum="03740BEDAF3755D4" modified="2024-05-29" version="1">MSGNNLVGEAVVENDLLDDLSSEPDYDYLAEEHNMSLEEQNNNNNDADYDSMPSTPDYDNLGADCEEEQSRGQQQYNNNDLLVAQTISMSAFPAIPSTNDFDNMDHKNIKTIVME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRZ4</accession>
    <name>A0AAD8XRZ4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016889</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000067">
        <property type="protein sequence ID" value="KAK1732408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="481"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="820"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1077"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1280"/>
            <end position="1309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="487"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="821"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1103"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1135"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1175"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1295"/>
            <end position="1309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1309" mass="147911" checksum="E5F7EA761BB314EA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSH4</accession>
    <name>A0AAD8XSH4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA polymerase theta</fullName>
            <ecNumber evidence="4">2.7.7.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_016611</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000060">
        <property type="protein sequence ID" value="KAK1732712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08638">
        <property type="entry name" value="DNA_pol_A_theta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.10">
        <property type="entry name" value="Taq DNA Polymerase, Chain T, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001098">
        <property type="entry name" value="DNA-dir_DNA_pol_A_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002298">
        <property type="entry name" value="DNA_polymerase_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10133">
        <property type="entry name" value="DNA POLYMERASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10133:SF27">
        <property type="entry name" value="DNA POLYMERASE NU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00476">
        <property type="entry name" value="DNA_pol_A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00868">
        <property type="entry name" value="DNAPOLI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00482">
        <property type="entry name" value="POLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase family A palm" evidence="3">
        <location>
            <begin position="1007"/>
            <end position="1256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="285"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="391"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="513"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="293"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="354"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="365"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="410"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="514"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1732712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1459" mass="163070" checksum="8B6D5C9B4AC021E9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSR2</accession>
    <name>A0AAD8XSR2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_016284</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000055">
        <property type="protein sequence ID" value="KAK1732953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSR2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1732953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="101" mass="11075" checksum="56D3BD203B35796B" modified="2024-05-29" version="1">MRAKSNSNNSKDKAVIDLQLHTIRQSPAETLASLSEACNTLGVESFDVYGDYQSNPQQSYLRQFESEVARCFGKDDAVFCLSGGMAQSIALMIHAKSHSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSU5</accession>
    <name>A0AAD8XSU5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000052">
        <property type="protein sequence ID" value="KAK1733206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSU5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="1">
        <location>
            <begin position="57"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="938" mass="105341" checksum="CCA662E64081BEFF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTG8</accession>
    <name>A0AAD8XTG8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015996</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000051">
        <property type="protein sequence ID" value="KAK1733279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTG8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="139" mass="15710" checksum="ABEE5CC837F09F66" modified="2024-05-29" version="1">MAEELIVDFPNHRSKRSVHFADTAKLHIVPRLDDNEDVHRHDLWYNKSDYSRMKLANRKSILKARAMASAGLPVSYSGDDGPSDECLIGIEHLLTPATILGVMACRRRCVRAVLQEQARQRMNPFSCETSGWDNNGFIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTY9</accession>
    <name>A0AAD8XTY9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016038</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000051">
        <property type="protein sequence ID" value="KAK1733321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTY9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44042">
        <property type="entry name" value="DUPLICATED HOMEODOMAIN-LIKE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44042:SF67">
        <property type="entry name" value="MYB-LIKE PROTEIN I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="2">
        <location>
            <begin position="293"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="1">
        <location>
            <begin position="293"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="409" mass="46979" checksum="D1628F943CE4CC02" modified="2024-05-29" version="1">MGPPMPQRLRPSRNIDIDRIEHPDDELLHEKRPPGKFPVAIEGKHIIAHGKPRTASTLLFNMVGVSNFLYLMRHEPKHVPYIEPKYIKDGQPYEEYLREGPAETTKIYKTHIDLDKFLRYDAVIFTTATTSKEAASVKSSLEKQGHDVAYVQDMERLKGGGIPRIAHDFAFGYDLPKDDEDEMVEYFSKWEILRQCCGEQMSKYWKNDLTPEVYKKLALKDHPHPFCADHDIDEIEKGFMETKLYSKLDAYPNMRPFNKPSLRDGELNGTYCSSYNERIKTQALNFYGQPLPMENIKTGNWTEEEHSIFLEGLKIHGSSKPSKIAKMLETRTVMQVYTHMKDYIQQQIQSGNDDDDELVKVMQRPALEGGDLAIGDLALAYDETGKLILVDKTSMSEIQVQVQKPSDDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XU80</accession>
    <name>A0AAD8XU80_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015856</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000049">
        <property type="protein sequence ID" value="KAK1733441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XU80"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042073200" description="Calcineurin-like phosphoesterase domain-containing protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="303" mass="33549" checksum="3D927B8D4CFB89A5" modified="2024-05-29" version="1">MIMNVCCNHLVILLLLSKMMRSSIASASIEKNDLSFLVIADLHVMSNFAFQSQNDSPSKIQLWKNLTTTLTHIRDNYMEETDLVIAPGDVAAFGNISNGEFMSQTGLSDENEAVYDASTTSYTKTNELYQGAGFGTYIPCVGDHEIGGNRGFVVSGQKSKFSSISSYRHGWIDSFMKDEDGSFKFNEGVSNISSRPPENSGFQGTSYAYRRKNSLFISLDIFKVMNDGISDYYDRSNGYGGEGAITSTLEGLHSTWFESILKAARQVSSIKHIFVEAQSLLCILFAKPVVVDVHFGDSWRNTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUL9</accession>
    <name>A0AAD8XUL9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SET domain-containing protein</fullName>
            <ecNumber evidence="3">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015421</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUL9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF121">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="416"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1063" mass="117140" checksum="3B9010F006BECFC5" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWT3</accession>
    <name>A0AAD8XWT3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC transporter ATP-binding protein, ModF-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_013965</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWT3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050086">
        <property type="entry name" value="MetN_ABC_transporter-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43166">
        <property type="entry name" value="AMINO ACID IMPORT ATP-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43166:SF9">
        <property type="entry name" value="GLUTAMATE_ASPARTATE IMPORT ATP-BINDING PROTEIN GLTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="60"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="364"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1735351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="616" mass="67901" checksum="8EB098FE4C2E4937" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XX72</accession>
    <name>A0AAD8XX72_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">STI1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013709</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XX72"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48313:SF1">
        <property type="entry name" value="OUTER ENVELOPE PROTEIN 61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48313">
        <property type="entry name" value="TPR_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="520"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="254"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="397"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="567" mass="60543" checksum="B4A964290A190A5B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXW9</accession>
    <name>A0AAD8XXW9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_013812</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXW9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051024">
        <property type="entry name" value="GlcNAc_Chitin_IntDeg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006970">
        <property type="entry name" value="PT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34823:SF1">
        <property type="entry name" value="CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34823">
        <property type="entry name" value="GLCNAC-BINDING PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04886">
        <property type="entry name" value="PT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042268573" evidence="4">
        <location>
            <begin position="20"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="797"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="799"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="832"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="850"/>
            <end position="861"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1735649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="977" mass="104961" checksum="023246D20CA2CCF8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZC5</accession>
    <name>A0AAD8XZC5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Hexose transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">QTG54_012524</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>D-fructose(out) = D-fructose(in)</text>
            <dbReference type="Rhea" id="RHEA:60372"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:60373"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>D-galactose(in) = D-galactose(out)</text>
            <dbReference type="Rhea" id="RHEA:34915"/>
            <dbReference type="ChEBI" id="CHEBI:4139"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="7">
            <dbReference type="Rhea" id="RHEA:34917"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>D-glucosamine(out) = D-glucosamine(in)</text>
            <dbReference type="Rhea" id="RHEA:78423"/>
            <dbReference type="ChEBI" id="CHEBI:58723"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:78424"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-glucose(out) = D-glucose(in)</text>
            <dbReference type="Rhea" id="RHEA:60376"/>
            <dbReference type="ChEBI" id="CHEBI:4167"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:60377"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-mannose(out) = D-mannose(in)</text>
            <dbReference type="Rhea" id="RHEA:78391"/>
            <dbReference type="ChEBI" id="CHEBI:4208"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:78392"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-xylose(out) = D-xylose(in)</text>
            <dbReference type="Rhea" id="RHEA:78427"/>
            <dbReference type="ChEBI" id="CHEBI:53455"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:78428"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZC5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015149">
        <property type="term" value="F:hexose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045263">
        <property type="entry name" value="GLUT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503:SF8">
        <property type="entry name" value="FACILITATED GLUCOSE TRANSPORTER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="17" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="187"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="321"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="349"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="446"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="482"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="511"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="540"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="574"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="602"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="16">
        <location>
            <begin position="192"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="63"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1736502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="690" mass="75423" checksum="2BF3CCBC93308C2B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y002</accession>
    <name>A0AAD8Y002_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">CobW C-terminal domain-containing protein</fullName>
            <ecNumber evidence="9">3.6.5.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_012796</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y002"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03112">
        <property type="entry name" value="CobW-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1220.10">
        <property type="entry name" value="CobW-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051927">
        <property type="entry name" value="Zn_Chap_cDPG_Synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43603">
        <property type="entry name" value="COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43603:SF1">
        <property type="entry name" value="ZINC-REGULATED GTPASE METALLOPROTEIN ACTIVATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00833">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90002">
        <property type="entry name" value="Hypothetical protein YjiA, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041980912" evidence="7">
        <location>
            <begin position="22"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="domain" description="CobW C-terminal" evidence="8">
        <location>
            <begin position="477"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="363"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="363"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="383"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="414"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="436"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="456"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00034320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1736774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="658" mass="71692" checksum="1DBE844C9E01FB68" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y160</accession>
    <name>A0AAD8Y160_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tc1-like transposase DDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011478</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y160"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038717">
        <property type="entry name" value="Tc1-like_DDE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46564">
        <property type="entry name" value="TRANSPOSASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46564:SF1">
        <property type="entry name" value="TRANSPOSASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13358">
        <property type="entry name" value="DDE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tc1-like transposase DDE" evidence="1">
        <location>
            <begin position="226"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="381" mass="44258" checksum="DD351DF162A4989B" modified="2024-05-29" version="1">MSTRDFAAQHGAEVNMHGGFYIRGKAHSIMKKMHVAEKYIQAKNRGEQRPNHTRIAQQCQVSRGFVSKIEAEILSNGQQILTPEEIRAATDRPGLPGANSLTDLDRFILVLLLEEKPYRLLRNYQQWLLYFTGTNVSTETISRFLKQGLPHKGSLVKPNLIPLDKFKIENEIRAYEFLNVLRTLKTWKVIFGDEKSLKGEEFYSKRVRRNPVTGMVASILTGADFRNKYSITGFCSINSDKSVPVWFRIHKQSNDANEFMRTIKIAVKEGYFDEYDVLVLDNAAIHDEEMVRWLWKTKKVLVLFLPTRSPEFNPIELIWRHLVSTLFSYPLMKPRGNTQYKRSPALVSRDILEEVTFDIVEKCFKKCFAFITEKLNDRDRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1I4</accession>
    <name>A0AAD8Y1I4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012184</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1I4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042037119" evidence="2">
        <location>
            <begin position="20"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="266" mass="28553" checksum="C032C4BCACF25D04" modified="2024-05-29" version="1">MRVTSLALALAVTTGSASAFSTNSVSSSRRNSQVVLNANADRRAILSSIFTATTAATLLSSSTIANAGLLDDYGTDPLDNKQPTKKEVVQARDKGKPESNLEPNLRSNYYYPTNKVRYLPRIKKCNDAIPGVADAIGNEDWEAVRNFATVVADDTILPLKLYVSSLGGGGTNVKVGFAKNMTTAAKQFEKNQALLVKAVDKKDGAKSSAALEQMAEALLTYRTEGRLLGPDGGGDIPSVDEIRRSTKRFRGEAFEAKSKCLYCVSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1I7</accession>
    <name>A0AAD8Y1I7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1I7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="151"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="269" mass="30547" checksum="B5945AE8EC2C1021" modified="2024-05-29" version="1">MDRDMLSIDQILPNTSAGDGDDVGGKALAIRMWISSVLRKIIRYKAQHHSLLNEAATTLQHALPQDIMMNNVLPFLELPSFTFEGGDTKRKRKKLQNDNARQDDNVANLSAMLKEGLLENEEQNDAIMMLNQQLTDALATMSMIVDSVRCNSELRIRVSELERENALFVEQRDELEQEVARLVEAGEALVEENDHLGDEVAILEILHEANEGLVEENEELLESSRVYQFVSIVCGAATRLTYRFRKRVNSNENNECYRPTKRVRLSDAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1R4</accession>
    <name>A0AAD8Y1R4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011303</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1R4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="89" mass="10081" checksum="FEB87A3BB9747F24" modified="2024-05-29" version="1">MNHFGTATNTKVPEAKRLKSGELKVDDDGIKNDKTSTDTKEALTLKDELQAAGFTAFRPLDDLGYFGWEPNTLRLMITRIIKSYNQYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1R8</accession>
    <name>A0AAD8Y1R8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Inositol-phosphate phosphatase</fullName>
            <ecNumber evidence="8">3.1.3.25</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_012107</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.25" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1R8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052834">
        <property type="term" value="F:inositol monophosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01641">
        <property type="entry name" value="Bacterial_IMPase_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051090">
        <property type="entry name" value="Inositol_monoP_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200:SF6">
        <property type="entry name" value="3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200">
        <property type="entry name" value="PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042133521" evidence="7">
        <location>
            <begin position="23"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR600760-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1737240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="388" mass="42422" checksum="BD5EB1B4BCECCA14" modified="2024-05-29" version="1">MKITASVTISLATILLRHVAEGFAYIDPSNGSIPGGNKKTEKIENEMQQSAVLLPDCDPQLLKEHAQFAYELADAARLEILPYWRQSRHTLGQEIKVEKDRSVFQSASPVTLADRAAERAMRELITERYPQHGVYGEEYGVIREDADWVWVLDPIDGTRSFITGKPLFGTLIACLYKGTPVIGVIDQCILNERWLGLAGQVSTLNGEPIQTDGVVTLNEAEMYSTTPDMFQHGDELNKFDAMRHAVKTPHYGADCYAYALVASGFGADIVVEADLGLYDYCALVPVLQGAGGSISDWNGVELTLQNHEISKGRVLACANAKLHEQALEILSKPGLESSDSLDVDDPSLTLLEDDIASSTFIPSAQRLTPWVGGIIVGDILEQILHHGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y263</accession>
    <name>A0AAD8Y263_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helicase-associated domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011649</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000024">
        <property type="protein sequence ID" value="KAK1737665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y263"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.530">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005114">
        <property type="entry name" value="Helicase_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33418">
        <property type="entry name" value="HELICASE-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33418:SF1">
        <property type="entry name" value="HELICASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03457">
        <property type="entry name" value="HA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase-associated" evidence="1">
        <location>
            <begin position="73"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase-associated" evidence="1">
        <location>
            <begin position="140"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase-associated" evidence="1">
        <location>
            <begin position="207"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase-associated" evidence="1">
        <location>
            <begin position="274"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="467" mass="54961" checksum="CD7F5802E55E7C94" modified="2024-05-29" version="1">MGRCKYSRGSCSIICCIRQLSSPTLHQSPLSVQLLPPSSNGFTLLYFPNKNIYGCNNRGFSSDGNNVPPVFYEERWDMRYQELVDYKEEHGDTLVPAKYPDKQQLGIWVDTQRQNRKNKKMSPGRVDKLNEIGFVWDPFEDSWNEVFQQLKQYMNEHGDTLVPRTYPDNLQLGNWVSNQRCNGKNNSLSQERIDKLNEIGFIWEPIEAAWEEMLQQLMKYKEEHGDTLVPAKYPDNLQLGIWVVSQRQNRKNDSLASERVDKLNEIGFVWEPLEAAWQSKYNKLNTFYKRYGHTKIPMGGDGDEELYYWCMRQRHSKSTCSLPRHRNDQLKRINFDFFTRKIAKGSSLIENMIIYELERMGHEFDMKNEVFFGVKYKYRPDGVILVDEAFAIFFEVDERHHSGYSIKKEHHRMEDLRKEAETQGYEQVTFVRVSTACRKQISCNESLSQLKFETTTMCSLPKNVLMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2L3</accession>
    <name>A0AAD8Y2L3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_010519</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2L3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042186737" description="EGF-like domain-containing protein" evidence="3">
        <location>
            <begin position="25"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="4">
        <location>
            <begin position="257"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="498"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="512"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1738489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="525" mass="58685" checksum="BB7E8A23D208DED9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2R8</accession>
    <name>A0AAD8Y2R8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatidylinositol-4-phosphate 5-kinase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011522</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2R8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.110.10:FF:000002">
        <property type="entry name" value="Phosphatidylinositol 4-phosphate 5-kinase 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215:SF14">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="226" mass="25540" checksum="0D8E138975FB5855" modified="2024-05-29" version="1">MNTNPGTVTINYSNGNVYEGSFQPHGIGKLKYADGRISNGIWKNGTIIYEGELADNNGEPHGRGRWTYSNGFYEGEWKNGLRHGEGMYKWTDGSSYCGQWKDDKKHGVGVKKWPDGSSYDGEWRENKKHGKGTKRHANGDVWYTGDYRDGRPDGVGTLNYSNGDVYTGQWRANKKHGRGLMTYANEEIYEGEWRVGVRHGSGSFMLTNGDVITGEWINDKMPLDMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2Z8</accession>
    <name>A0AAD8Y2Z8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Pheophorbide a oxygenase</fullName>
            <ecNumber evidence="15">1.14.15.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_010527</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.15.17" evidence="15"/>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2Z8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010277">
        <property type="term" value="F:chlorophyllide a oxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032441">
        <property type="term" value="F:pheophorbide a oxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050584">
        <property type="entry name" value="Cholesterol_7-desaturase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013626">
        <property type="entry name" value="PaO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21266:SF32">
        <property type="entry name" value="CHOLESTEROL 7-DESATURASE NVD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21266">
        <property type="entry name" value="IRON-SULFUR DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08417">
        <property type="entry name" value="PaO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Rieske" evidence="14">
        <location>
            <begin position="82"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1738497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="547" mass="60656" checksum="D10D2AE6B46486C0" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3V6</accession>
    <name>A0AAD8Y3V6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein LOW PSII ACCUMULATION 3-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010985</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3V6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018962">
        <property type="entry name" value="DUF1995"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044687">
        <property type="entry name" value="LPA3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34051">
        <property type="entry name" value="PROTEIN LOW PSII ACCUMULATION 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34051:SF2">
        <property type="entry name" value="PROTEIN LPA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09353">
        <property type="entry name" value="DUF1995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041965767" evidence="1">
        <location>
            <begin position="20"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1995" evidence="2">
        <location>
            <begin position="70"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="389" mass="42868" checksum="0EBE787A7DE701F8" modified="2024-05-29" version="1">MKLSITALALALSLSSSHAFTPPPTLSSLQSFTSNNRHETLISMNIPAPTASGGATPEEIQAAANNEPPPSSFFELQRASVRAAQAAINDGKTLLEVEFPPLPAQVLDMDDVSAYDVAKANVNLALDFARSFVSTDEIEGDVAVMLPDESECNIMLEDLKLEPKPYPGVILTSLRKGEEGDTRMFKPENLFIGLMGRGSGGTVKPIEGVGMYVIVVASAQELPDVEELYEQIKTPTTDGGKEPVIVFYNLKLDVLRGDLGAPAFPGKDFQDRFLSRVKPVYYLRTRQYSRSVSQPPFIINFQGCIFRSYPGHFQTLLDTGTGRYRKVVGNDLRPALGEFKEQLTDALREEGAIAKKEEEGALFGFLRTGYKTTTWWEDEREDASLEWRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6F6</accession>
    <name>A0AAD8Y6F6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-CH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_009008</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6F6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-CH-type" evidence="4">
        <location>
            <begin position="12"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1740058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="134" mass="15387" checksum="F0860DE1F424CE85" modified="2024-05-29" version="1">MSLKRFASVTGLLEEEAPCCWLCLEEGPDASDKPLCRDCSCRGTSGFVHLSCAVKYAENMSRDDADEEYEYPSAFFRTCPNCKQDYQGDVAYALAKARVDFVEREYKNNHEMCLDAMRENLHALDFKDEQRRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6U0</accession>
    <name>A0AAD8Y6U0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008906</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6U0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="205" mass="23315" checksum="C6C020A962E4C3AC" modified="2024-05-29" version="1">MGNNASNNSDRMAISAMSHMMNITKPQLLQLRDNCISASIKDGSTPSGYKLRRENFLQAMRDSRISIEPDYQVLEKLFTMWDRNSYGVDTLTFFAGISPLASIMDVNTKLQYAIEVYDYKKTGRVSRISLVRILQAINETSSYFGDKVLIPRQIVVIVDDLFDGENRLEDDDAIQYEGRVEKIACHPFVMEFSNNKGSSRYGNVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6Z1</accession>
    <name>A0AAD8Y6Z1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sirtuin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008123</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6Z1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="453"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="484"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="523"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="627" mass="69579" checksum="8B16D71C9AEF9131" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y735</accession>
    <name>A0AAD8Y735_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008198</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y735"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="80" mass="8847" checksum="40C942BAD2E1224B" modified="2024-05-29" version="1">MCRLGQGGPEDKSEAAHYYTLAYSQKGLSFEKDEIAPLEISDDLRDEVLHAGLFLGIYHFMAKADSPKCVHCQVLFGGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7M5</accession>
    <name>A0AAD8Y7M5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7M5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="1">
        <location>
            <begin position="187"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1168" mass="131721" checksum="FBCBCEFB80B34033" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y822</accession>
    <name>A0AAD8Y822_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_008464</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051830">
        <property type="entry name" value="NOTCH_homolog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24033">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24033:SF151">
        <property type="entry name" value="NOTCH 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="4">
        <location>
            <begin position="462"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="4">
        <location>
            <begin position="651"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1254"/>
            <end position="1311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1262"/>
            <end position="1277"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="489"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="674"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1741212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1409" mass="155163" checksum="F1046035F58ADBC0" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAJ0</accession>
    <name>A0AAD8YAJ0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">OSTA/TMEM184 family transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_007603</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAJ0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005178">
        <property type="entry name" value="Ostalpha/TMEM184C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23423">
        <property type="entry name" value="ORGANIC SOLUTE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03619">
        <property type="entry name" value="Solute_trans_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01417">
        <property type="entry name" value="Solute_trans_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="307"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="475"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="475"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1742030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="514" mass="57502" checksum="119583FC227403F9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAM3</accession>
    <name>A0AAD8YAM3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007648</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="404"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1857"/>
            <end position="1941"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1955"/>
            <end position="2085"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3229"/>
            <end position="3260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3317"/>
            <end position="3339"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="463"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="598"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="661"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="822"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="967"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1093"/>
            <end position="1577"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1616"/>
            <end position="1699"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1807"/>
            <end position="1848"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2185"/>
            <end position="2276"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2310"/>
            <end position="2337"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2370"/>
            <end position="2397"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2437"/>
            <end position="2464"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2507"/>
            <end position="2592"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2653"/>
            <end position="2726"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2787"/>
            <end position="2821"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2854"/>
            <end position="2881"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2942"/>
            <end position="3178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="80"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="126"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="229"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="261"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="412"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="434"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1894"/>
            <end position="1905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1916"/>
            <end position="1928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1929"/>
            <end position="1941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1966"/>
            <end position="1987"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2016"/>
            <end position="2026"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2073"/>
            <end position="2085"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="3345" mass="383463" checksum="21377A87F4D00EEA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAT7</accession>
    <name>A0AAD8YAT7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_006903</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAT7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1742338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="141" mass="16162" checksum="AC9B36DFD7FA521F" modified="2024-05-29" version="1">MAAEIAREIIAQSKGGSKFAFSFFYTNRDCNLLIFSSTCASNERAVYYVHTANGDRMYEIRCNDVSSAATLVEGLLEKKIRSLMNSRLSFFDWSKTYMKLVFYEGGVVGAEFLRYHFPISDQRDFICQNLAFLNNIDVIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAY8</accession>
    <name>A0AAD8YAY8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RING finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_006805</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
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                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAY8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042862">
        <property type="entry name" value="RNF32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14991">
        <property type="entry name" value="RING FINGER PROTEIN 32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14991:SF0">
        <property type="entry name" value="RING FINGER PROTEIN 32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042019165" evidence="4">
        <location>
            <begin position="24"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="461"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="520"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="32"/>
            <end position="118"/>
        </location>
    </feature>
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        <location>
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            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="618"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
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            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
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            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="258"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="285"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="304"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="626"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1742240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="715" mass="81063" checksum="235B3C24DD36E8CA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBB5</accession>
    <name>A0AAD8YBB5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA polymerase delta subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_007508</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA polymerase delta/II small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBB5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007185">
        <property type="entry name" value="DNA_pol_a/d/e_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040663">
        <property type="entry name" value="DNA_pol_D_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024826">
        <property type="entry name" value="DNA_pol_delta/II_ssu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10416">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10416:SF0">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18018">
        <property type="entry name" value="DNA_pol_D_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04042">
        <property type="entry name" value="DNA_pol_E_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA polymerase delta subunit OB-fold" evidence="5">
        <location>
            <begin position="51"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="DNA polymerase alpha/delta/epsilon subunit B" evidence="4">
        <location>
            <begin position="246"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="223"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF18018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1741935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="527" mass="56638" checksum="3B7E788D10635AAE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBW1</accession>
    <name>A0AAD8YBW1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_005201</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBW1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060285">
        <property type="term" value="P:cilium-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036159">
        <property type="term" value="P:inner dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033290">
        <property type="entry name" value="CCDC39"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18962">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18962:SF0">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24161">
        <property type="entry name" value="CCDC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="25"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="312"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="122"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="611"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="92"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1743604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="656" mass="75751" checksum="3152AC36B414DF28" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBY2</accession>
    <name>A0AAD8YBY2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycosyltransferase 61 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBY2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049625">
        <property type="entry name" value="Glyco_transf_61_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyltransferase 61 catalytic" evidence="1">
        <location>
            <begin position="215"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="385" mass="44655" checksum="F27802BED756D0D7" modified="2024-05-29" version="1">MEDKISDSSTEQLGRQRILRRRRIRRLAVALITFALAFRNITQLKIDPPTRRTWEAIIHNSSCQTEPGSELIFTTNASVFPHPPEFTSISTLFPRFNYSQPKFACWYACPMHHPHFVQELFRCFSLWEIQPSHHPRVLYVPKRQFWRKIGNLAIFDKQFPISSGILRTLMNSYNVTVTNSWNDGTPLRVQEMMEKDESVSPFAMVSREHAVKWRDLFVPPEEEPTSRRAKKRLKIAVVNRPVARKLLNAMDARDNIAAAFPEHDVFEHHLNGTLQEMIDFFPMVDVLVSPHGSQLTGIMFMQRCSAVLEMFPHLYYTPTYFSSLARMFQLLHANWYVSHAAVPTGFLDLKTRLANTNNNMCPSMEKLVSAVDELIQKRQDCIDSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YC02</accession>
    <name>A0AAD8YC02_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YC02"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="178" mass="19755" checksum="CD069A3D1FA43C69" modified="2024-05-29" version="1">MTSQLQIFEEERRKLLLHEQNLITAHNDHLTKLHSHLSQLDGHILRLKQSESQQTSEDQQARGKSSEKVKVKVGAKAKDTTSSADAWQCLCGNMLKGDRKRCGKCLKWRGGKRGKSNADSNPPIIQRVVSSNDDEWVPTTTKRKRGRKASRDSASAVPAVTQDDEQAAASLLSLSLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YC11</accession>
    <name>A0AAD8YC11_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ethanolamine kinase</fullName>
            <ecNumber evidence="3">2.7.1.82</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006860</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from ethanolamine: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the choline/ethanolamine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.82" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YC11"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004305">
        <property type="term" value="F:ethanolamine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05157">
        <property type="entry name" value="ETNK_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603">
        <property type="entry name" value="CHOLINE/ETHANOALAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603:SF66">
        <property type="entry name" value="ETHANOLAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01633">
        <property type="entry name" value="Choline_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1742295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="471" mass="52918" checksum="6B892A3CF8A7E5F1" modified="2024-05-29" version="1">MPPSLYIRTRKLSQEPSNSNESFFSKVVDSHPYFPNLSVSASDISSVKHAALVLVYSSLLLRSNGCQLDDEVEHKKKLVEFFDANFGGTQESSAMSQLSCTKVTGGITNALFRVSGFQSITSLTAADFDSVLVRIFGAEGMIDRDIETSTYAALCNADIAYKYMGRFSNGRIEGWLDGYHPLQNQDLTDEATSLEIAKEMARLHCLFDVPEGELRDHHCGTELDVISVGLWDQLSSWMEQAKGYSEFKTAKDTERARALQLDKIEVEVQTIIQSFAATEEENDSGDSTASICGSSSKPNVVFCHNDLLLGNIMKNKTTGHIQLIDFEYGGSNYAAFDMANHFNEYAGGTTTKENGVPDYTRFPNSERQTKFCVEYVKMTKRLESMKSDITDQADYNGGQKEMVIEEDEGIMNEAIQLLSHVQNFILVNHLYWGLWAVNQAAEEGCEEFDYLTYASNRFNEYYVKKSEWEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCR3</accession>
    <name>A0AAD8YCR3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_006267</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCR3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1742670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="335" mass="38176" checksum="9830907EA1FC65F4" modified="2024-05-29" version="1">MCLGYQVKALPVSNIQAEGRDDDDDEIFVYMGGDQVVPDDVRRVRIDKSVTIIPRDVFYHREHLIDVEFHDGIEMIGKWAFKCCRSLRSVKLMGVKIIAAAAFYFCTSLIDLEFGDKLETIGTSAFQFCTSLRSVIIPSVKTIGKRAFATCRQLTDLDLPEGLETIQERAFSNCHELKQIAMPLNCNCVVIAIELFWLCPKLITVDLVGGFHNTVASLHLDSWRNEMKDEINHINQVLPNTDARRKTAEIKQWMGLVTRRLNHFKVEHKAMLKEATTLLELALWKADLNEKEEGLVEREGVRTTRGRRKRARKEICITSGASIVIKNVLPFLELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD89</accession>
    <name>A0AAD8YD89_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_006070</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD89"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052585">
        <property type="entry name" value="Lipid_raft_assoc_Zn_ADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43482">
        <property type="entry name" value="PROTEIN AST1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43482:SF1">
        <property type="entry name" value="PROTEIN AST1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="4">
        <location>
            <begin position="182"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1743449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="527" mass="57217" checksum="362450A1C6C774C6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDA2</accession>
    <name>A0AAD8YDA2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005659</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDA2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="139" mass="15646" checksum="5487CFAEFD9B159A" modified="2024-05-29" version="1">MMNDDKMSSSDGVEISSDILFGRGNSMKMASPQVNALLRKSAHDDHAALRDDEESVASSVSSSKMARCRGKSKAETNNRRHVFDELTKVKLNTSLAHPGRGEMWFGDLDFDFDINGEWVQDTRRGVLEEQRTTHVCHFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDA6</accession>
    <name>A0AAD8YDA6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DUF866 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_005968</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0587 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDA6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008584">
        <property type="entry name" value="CXXC_Zn-binding_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12857">
        <property type="entry name" value="CXXC MOTIF CONTAINING ZINC BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12857:SF0">
        <property type="entry name" value="CXXC MOTIF CONTAINING ZINC BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05907">
        <property type="entry name" value="CXXC_Zn-b_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141678">
        <property type="entry name" value="MAL13P1.257-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1743347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="188" mass="20775" checksum="C3BF0FE1932E8F21" modified="2024-05-29" version="1">MVLFVLCIKAELDGVESLSLLKNTNICFSVRNPLSDYETREKIVFDPSETLEQDEGDREPPHHFAVRWEGQKKFSTLIVLDEEGAKSAFKKMKKKGGKKKGGGGGEADVPRDMTADDSGEYVPVLAMECRGVEPYAFHPLGNEFKVTSSGGAVFEEDVDLSEGDWGDYDEENDEAVGVNEFESKIISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDF2</accession>
    <name>A0AAD8YDF2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase S74 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_005842</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDF2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030392">
        <property type="entry name" value="S74_ICA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13884">
        <property type="entry name" value="Peptidase_S74"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51688">
        <property type="entry name" value="ICA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042265948" description="Peptidase S74 domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S74" evidence="3">
        <location>
            <begin position="283"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="366"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1743221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="398" mass="43669" checksum="96BCDFDF4077BD14" modified="2024-05-29" version="1">MNLLSISICLAFSLTPSVAAWSSKRQETILDEDGNEWAVIDYDPETKAAKFDRFIASSFHGDSLDFRGREVRNAAIVDSSIEGIQHLTVESIAIRQASSTGTKNGHGPAIIDGDGVVSSTPHMRWDVQSKELRVPALGSFGSKLEVRSTVDFLSHTLRNVVLEPDTELQGLTFKDGIIENSILRNVTAVDLNLGDVVVETVSINEFTASNNVGAFVTVAENGKLDASSTMKSNEGQLLIDDDVIMSKSLQVEADLQVSGEAYLGGSLAVAGSVLGGGPYVDISDRRYKRNVQHLNSSEVLNDLLQLKGVSYELDTEQMTYLSGSKANAKKERQVGFIAQDVEVLFPELVYNDKDNDFRGVYYSRFVPLLVESLKQLTQEVRELQELNKQCLQAIKDKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDM1</accession>
    <name>A0AAD8YDM1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein L12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_005256</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDM1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00387">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1390.10:FF:000001">
        <property type="entry name" value="50S ribosomal protein L7/L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00368">
        <property type="entry name" value="Ribosomal_bL12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_bL12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_bL12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_bL12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00855">
        <property type="entry name" value="L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL12M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="ClpS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein bL12 C-terminal" evidence="5">
        <location>
            <begin position="167"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="140"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1743659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="234" mass="25228" checksum="94EF2F3A069B426F" modified="2024-05-29" version="1">MAYRLERLAINACRRSRVVGQINKPSSTSCTSSYQIINSCARRPIVSTAFDSVRLQQQHQPIVSATSCRNFHCTTRNQDDSNDGGAAPAVETAPFTSPKVEELFNKIILLDMIEVHLLAELINEKMGLKISDAERERMARGGGGGGGGGNKGDDDEAAPAAEEKTIFDLKLTGFDAKAKIKVIKEVRAITALGLKEAKDLVEGAPSTVKKDIKMEEAEELKAKLEALGATVEIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YE98</accession>
    <name>A0AAD8YE98_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YE98"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="560"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="560"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="874" mass="101131" checksum="B223612BC0A605A2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEA9</accession>
    <name>A0AAD8YEA9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Zinc-dependent metalloprotease (Family M12B)</fullName>
            <ecNumber evidence="5">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_005586</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEA9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001590">
        <property type="entry name" value="Peptidase_M12B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33683">
        <property type="entry name" value="1, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33683:SF46">
        <property type="entry name" value="SUSHI DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13582">
        <property type="entry name" value="Reprolysin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50215">
        <property type="entry name" value="ADAM_MEPRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042016554" evidence="3">
        <location>
            <begin position="23"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12B" evidence="4">
        <location>
            <begin position="265"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="199"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="467"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="717"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="199"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="468"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="511"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="719"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="739"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="404"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="407"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1743989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="755" mass="82283" checksum="FD7995240C691ED5" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEQ8</accession>
    <name>A0AAD8YEQ8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cyclin-dependent kinase 2 homolog</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cell division control protein 2 homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">cdc2-related kinase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_004440</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">May form a complex composed of at least the catalytic subunit CRK2 and a cyclin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEQ8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030332">
        <property type="term" value="F:cyclin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000082">
        <property type="term" value="P:G1/S transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010389">
        <property type="term" value="P:regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF254">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="14"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1745149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="447" mass="49142" checksum="628AE7AAB2953DDA" modified="2024-05-29" version="1">MMSYTVEICNDGSSSINPLIARGAFGHVDIALIVGWQCPSPDADAKKEKAAIHSVKLAAIKTIPNATNKSSGALTREAFAELNALRLLNGHANVTPLLGYYGARDKFGSGWDWGGNELGNLSSLCLVFPYHPIDLAEALHYRRLQCFADGSPHQHSHLPHDVVKSVCCDILSALEHLHSHHILHRDVKPGNLYITKDGRVELGDFGLAKVIPIDNVDQIESETGLCTLQYRPPELLLGGNGIVDKVEASRGAMDIWSAGCIFAELVTLSGPLFPGQSVLDQLARIFHVLGTPTEEDWQGVSQLPDWNKVTFEHQSGKELQEITGKCLWSDGVVELTNTMLILDPLKRPSAQQCRQSFNLNDDVVRMHGYESVVKALIPSSLLTEDPIYVGTHSTEHDRLAYAKLCASRVACARRNFPKSLNKTAKQDDSAKWRCKSKPRHITSALYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YET3</accession>
    <name>A0AAD8YET3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">thermospermine synthase</fullName>
            <ecNumber evidence="5">2.5.1.79</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_004777</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>S-adenosyl 3-(methylsulfanyl)propylamine + spermidine = thermospermine + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:30515"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:57443"/>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
            <dbReference type="ChEBI" id="CHEBI:59903"/>
            <dbReference type="EC" id="2.5.1.79"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.79" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YET3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010487">
        <property type="term" value="F:thermospermine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006596">
        <property type="term" value="P:polyamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.140.10">
        <property type="entry name" value="Spermidine synthase, tetramerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00198">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001045">
        <property type="entry name" value="Spermi_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035246">
        <property type="entry name" value="Spermidine_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037163">
        <property type="entry name" value="Spermidine_synt_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43317">
        <property type="entry name" value="THERMOSPERMINE SYNTHASE ACAULIS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43317:SF1">
        <property type="entry name" value="THERMOSPERMINE SYNTHASE ACAULIS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17284">
        <property type="entry name" value="Spermine_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01564">
        <property type="entry name" value="Spermine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PABS" evidence="7">
        <location>
            <begin position="63"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1744244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="423" mass="47419" checksum="F9BDD28B3228836C" modified="2024-05-29" version="1">MHYARQLIGNNYAPYKHFATCLLLQLRNLSFSQTTTKPPLFITHCKKMADHDEIIDKERSKSAFKYVEDIAPGLRLEMDLDKIHHTSISDFQEVQVIDSYFGKTLVTDGKTQSTAHDEFVYHESLVHPPLFWSALLSGTTESDGTRIPGSAPKSVFIGGGGELATAREVLKHNSIERLVMVDIDPKVLEVCKQYMPEWGGEAVVSHPKMELIVGDAHKYLMETQEKFDVIIMDISDPIEAGPGIALYTQEFYQRTSEVLSKPNGVFVTQAGSADFIPHPHAFPEDDDDDNKESWCFSPILNTLATVFDHSIPYAVPVPSFGECWGFVMAFNGDAKEARALADLPYEVIDNLIEERIEAVPGVPDHKYRSKGVKFLTGKEKGSEALKHYDGVTHRGLFSLSKSLRIAMKGDKRIMTVDNPVFMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEW8</accession>
    <name>A0AAD8YEW8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005538</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEW8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1743941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="163" mass="18084" checksum="E55889898B260EC6" modified="2024-05-29" version="1">MKKSSYVPKAMNLASIQWHWLEDMASKYKLSSTSKAMRCCINCVALGDAQMESDGGCCGCNNTITKEVELSTEQLTWVEGQYNQCDDDNNDDSTLSIEQKVVSACMKLDEYTVFGIIRCKSSVAKCEGAQEAVENIQQQFSVEKDEVVTKENIDICAKNCGCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFI6</accession>
    <name>A0AAD8YFI6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFI6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041978703" evidence="1">
        <location>
            <begin position="18"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="89" mass="9362" checksum="9ECD4AA7994226D4" modified="2024-05-29" version="1">MARYLFILALIATGASAFYKGAVPQQEGPKIPAAAAGLLDNPAVASDPNINPARKCGFCMGVMIRADELPRLWTLSPDRNSSDISGGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFZ7</accession>
    <name>A0AAD8YFZ7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein-serine/threonine kinase</fullName>
            <ecNumber evidence="1">2.7.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004524</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PDK/BCKDK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFZ7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004740">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010906">
        <property type="term" value="P:regulation of glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039028">
        <property type="entry name" value="BCKD/PDK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947:SF3">
        <property type="entry name" value="[PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 2" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="243" mass="27432" checksum="75A8FFC07CF57CB4" modified="2024-05-29" version="1">MNSFTSAIRSSLLQNANKGDSLRRWSINELLKLNDVNATNAEVVLQEIRTRLAIQHQRLSSFPRVEEYAKIASSSDGATLSKSLKMLLQLHENTYMLPHEIIETDYLMEGFSNRPKQMYLKQMVDDIMTRHGASVDTFADAAIASRNMEHQIPQILRKQFRTDATILQNPEPFLHSRLLIQLICEHYVSLNKGKPTGAVSIDADILDIVDDATTEAKHVADANLGIAPEVRLEVLMDHLSLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YG71</accession>
    <name>A0AAD8YG71_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004156</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YG71"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="46"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="102" mass="12123" checksum="BD84D37BED09F1DB" modified="2024-05-29" version="1">MVKNPPRNISTTVSAAIATQTSERVDEAKQLQLIKEKQYQEKMSEFGKLELEAKMVTERMRQIEERMRQIQSTSISNDLREYDEMKGVHRMLRRHCVRRRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGK2</accession>
    <name>A0AAD8YGK2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">IFT88-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004351</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGK2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042202749" evidence="2">
        <location>
            <begin position="26"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="236" mass="25340" checksum="62DBE4F158DF4D6E" modified="2024-05-29" version="1">MPLAINNAMLASFLLLLFLPSPTSGFAAWLKCSRQLEADEIIMNNKVRHAGEENDASVVKLAVYDESGSTRVDVASDNGGGGAIVWIDNDFTSLSFKIGLDQSTLSDLSDIQYVVESTPFYASPSPRPAPSPNVPTINSNKKQRNAKRTSFTGASGVGGLLCNGKRAHARGKNGNVTYTLVPNKVSDTNKDGIIAEVWGGWSEYHGDVTLTPRIIFKKKDSASLEIGQDQHGQGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGP5</accession>
    <name>A0AAD8YGP5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SAM-dependent methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004046</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGP5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052514">
        <property type="entry name" value="SAM-dependent_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01444">
        <property type="entry name" value="fkbM_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34203:SF13">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34203">
        <property type="entry name" value="METHYLTRANSFERASE, FKBM FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase FkbM" evidence="2">
        <location>
            <begin position="136"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="356" mass="39067" checksum="E8EB92E8BFB6B4D3" modified="2024-05-29" version="1">MTSTRRIYIIVIIAVAMLVVAQNLSSPSCFVFQDGQRNVEDTDNNSAHVRDSLASTAYPLANPKPGFSLLGDRGVVAGTCADIGWNYVFSYAEDIRSQKWDLQALKSHRTQGVATKLCGYGYDKYFDGARGYTMLDIGANMGLSLMPYYSKGWKVVAFEPIKDNINTLRRNLFINGITEDQVALVEGAVTNQSGILEIYAPRGRTDNTALSRKGSTLNVGGDVDVEKVTAIEIDTYINNAVSSDLRRNIMLVKIDTQGHELNVLQGMKSFLSAPPSNEDLGGWSFVVVAEYHVGLQKAAGHDPNEVLNFMRSLGYEVRCKLTDIDPILPPASPKCGDVIFSKGKPLNLNQVWNSNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YH28</accession>
    <name>A0AAD8YH28_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003787</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YH28"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="558"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="624"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="811"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="342"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="636"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="838"/>
            <end position="851"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="898" mass="99724" checksum="5FAF5AA2CE416F55" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHC2</accession>
    <name>A0AAD8YHC2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004603</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHC2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="268"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="295" mass="31706" checksum="CF8E603359CE0D22" modified="2024-05-29" version="1">MGHLSFFTAAYVGGGATASTFGGEDTSAMSSLVARPQQERQQQRRRRPVINSASSKAVSSIFVAALLLCMLAFAAAQDEPKCNCSPVGYTFELKLDAYTCPDPENSITPDDAVAYFGPGVKAYTCNPGSPIPVTITQAQFIVSDETNNPVLTQTKDSLELTDGETLTFTSVTTNPPLVGFILLKLVGEDINGVKIESRWTIQFTNECGVLSLEDGTEFSLVIFRDLERPSKTLCPREDPPPPPDGSYSYLRAFSKAGKGSKHTRHSSSKSGKNLNSKYDGYGGKSSKSKSGKSKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHL7</accession>
    <name>A0AAD8YHL7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002859</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHL7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="169" mass="19273" checksum="900A81ECBC1DD6E0" modified="2024-05-29" version="1">MNQNYASNAEEGARNFKKKLALAKASKRDQAIVEHFLRGTLTEQPSYHTTMDEHGHVQHYNEFDIYASWDDEKPIHLVHTNQPFDKKDAFPSAKPVVFTGCFLEDDVHEIHPITAKLSFKKEKGKSKLIASGDVLMYFDHFEVNGWATKMKNNEYQIELRALPAHGVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIQ9</accession>
    <name>A0AAD8YIQ9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002367</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIQ9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="334"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="365" mass="40856" checksum="D8EAB883D24DC433" modified="2024-05-29" version="1">MTFSYAGEAITDADAADTNQIASSVDAPPPSAANAQQNQATSTGESDKPEFPFFKERREPWFWFNNVAFLVCLAFFFYFTVTIVQDFIDNRNDPPTATTLRNGFSQSFPAMGFCIHRGLDPNSTQPDLQPLFAQYDNSDENAVDITDQLKEIDCPNVPQNQKCWYLDGNYAAFDVDCGGIRRNGISLGFTFNMTEYSREVTLLGIDGFLFESQNREQFFSLACPRCTDDTLPIDDMCQNGYLGFESFFATALTTNLIQLHRSETQANARCDTKIVQWNAASVAAAVNPKFLDGINVTNSASTVLMDFQFFSADITKTTFNPQSGVSMFGSLSGWFGFLSDGWGILSLLFIVEELITYCFRWRGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJ93</accession>
    <name>A0AAD8YJ93_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002667</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJ93"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="297" mass="32962" checksum="EA655A76F2009A23" modified="2024-05-29" version="1">MGGERSSALPGDKALIRNSSGRANYRYRAPAIAIGPFMHGPTDMRIHAGEHRLFRSIREEEDEDEEAARSVSPMIASFTGESCKAPYARASSQPAASHRNETWDDDVTTTTTSSAPIAAPHEPSNCVKSIISHISDDSCSTRKQSLPLKPSLNSDASSKCRVAKHVHFTFTDKEMSYEVTSDDIENSWLDIDVSRAIEALENGSHDAIVSFGPTGRFTSSDLDVCKNGKEYMVRIQKRRLINEMLGQRTNLRQSVFEEQARQKRNGVVDAEELHAVASEQSKWGVEIAKSSWWLCQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMN6</accession>
    <name>A0AAD8YMN6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">mTERF domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_001909</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the mTERF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.70.10">
        <property type="entry name" value="Transcription termination factor 3, mitochondrial"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003690">
        <property type="entry name" value="MTERF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038538">
        <property type="entry name" value="MTERF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13068">
        <property type="entry name" value="CGI-12 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13068:SF151">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR MTERF9, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02536">
        <property type="entry name" value="mTERF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00733">
        <property type="entry name" value="Mterf"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="16"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="235"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="177"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1747946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1909" mass="217005" checksum="3C7613056E617A21" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YN47</accession>
    <name>A0AAD8YN47_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000997</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YN47"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="107"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="79"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1749058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="198" mass="22782" checksum="1B315D1B868E5EA8" modified="2024-05-29" version="1" fragment="single">KEIRFDFAHDDDDDSTDVPSYRGRQPYVGRQKYITRPTTASRYDDNILEQRNFEDQVEEVLGWLKDEMERSQSFVHRSRQIHDAELANAKREMDKLKKAAKRIIKAVHKKGKDKAARSEATADSERRRRIKSQKTMASMIKSHSAQMEHLKKGLHRNSTYDTGSDSLAGLGLDLEDDSHAIRDETIQPNCSALRAILI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YNI8</accession>
    <name>A0AAD8YNI8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="21">Lysosomal dipeptide transporter MFSD1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="22">Major facilitator superfamily domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="27" type="ORF">QTG54_000431</name>
    </gene>
    <organism evidence="27 28">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="27" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="27">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="23">Lysosomal dipeptide uniporter that selectively exports lysine, arginine or histidine-containing dipeptides with a net positive charge from the lysosome lumen into the cytosol. Could play a role in a specific type of protein O-glycosylation indirectly regulating macrophages migration and tissue invasion. Also essential for liver homeostasis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>L-alanyl-L-lysine(out) = L-alanyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79415"/>
            <dbReference type="ChEBI" id="CHEBI:192470"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-alpha-aminoacyl-L-arginine(out) = L-alpha-aminoacyl-L-arginine(in)</text>
            <dbReference type="Rhea" id="RHEA:79367"/>
            <dbReference type="ChEBI" id="CHEBI:229968"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-alpha-aminoacyl-L-histidine(out) = L-alpha-aminoacyl-L-histidine(in)</text>
            <dbReference type="Rhea" id="RHEA:79375"/>
            <dbReference type="ChEBI" id="CHEBI:229967"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-alpha-aminoacyl-L-lysine(out) = L-alpha-aminoacyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79383"/>
            <dbReference type="ChEBI" id="CHEBI:229966"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-arginyl-L-alpha-amino acid(out) = L-arginyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79371"/>
            <dbReference type="ChEBI" id="CHEBI:84315"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>L-arginyl-glycine(out) = L-arginyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79391"/>
            <dbReference type="ChEBI" id="CHEBI:229955"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-aspartyl-L-lysine(out) = L-aspartyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79411"/>
            <dbReference type="ChEBI" id="CHEBI:229953"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>L-histidyl-L-alpha-amino acid(out) = L-histidyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79379"/>
            <dbReference type="ChEBI" id="CHEBI:229964"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-histidyl-glycine(out) = L-histidyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79395"/>
            <dbReference type="ChEBI" id="CHEBI:229957"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-lysyl-L-alanine(out) = L-lysyl-L-alanine(in)</text>
            <dbReference type="Rhea" id="RHEA:79399"/>
            <dbReference type="ChEBI" id="CHEBI:229954"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-lysyl-L-alpha-amino acid(out) = L-lysyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79387"/>
            <dbReference type="ChEBI" id="CHEBI:229965"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-lysyl-L-lysine(out) = L-lysyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79403"/>
            <dbReference type="ChEBI" id="CHEBI:229956"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>L-lysyl-glycine(out) = L-lysyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79407"/>
            <dbReference type="ChEBI" id="CHEBI:191202"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="24">Homodimer. Interacts with lysosomal protein GLMP (via lumenal domain); the interaction starts while both proteins are still in the endoplasmic reticulum and is required for stabilization of MFSD1 in lysosomes but has no direct effect on its targeting to lysosomes or transporter activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Lysosome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="27">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YNI8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052187">
        <property type="entry name" value="MFSD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0458">Lysosome</keyword>
    <keyword evidence="6 26" id="KW-0472">Membrane</keyword>
    <keyword evidence="28" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 26" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 26" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="196"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="297"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="463"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="488"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="521"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="550"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="25">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="25">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00044898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00044899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00044900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00044912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00044919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00044924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00044985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00045018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00045709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00046376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="KAK1748492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="609" mass="66605" checksum="0E8A61B517124D35" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YP19</accession>
    <name>A0AAD8YP19_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000455</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YP19"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="216"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="29"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="332" mass="37450" checksum="67BB62DC7B551649" modified="2024-05-29" version="1">MESKVPQLIAVSTDSSASSLEDLFDAERQKKLDSERQKKEKEEYAQEQRSSGVKEFITSIGDRVVAFYDSSFLAVQPPRSWAPNLDISAAVLSNPLFICAYVDDKVCGYVDDRVDQRGSQKPHTSRSTAVNTESQVQFHRGLDIPVKSTDQLLNEICETTLANARKEFLTREALEDAINMNAEAAEAGNEQADEELRRLFPLRFVLPTAADMTEMIEALQKKKTNAMRHVNMTEANKIQAEIDELEYQVQKEETYIRKREISQTECVACEQQFSIQEIKPGDMLHCKECRLVFSNDNASETFTLTQRPLKSSLSITVVRKGKGRTPLIPSDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPE3</accession>
    <name>A0AAD8YPE3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SNF2/RAD54 helicase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPE3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10799">
        <property type="entry name" value="SNF2/RAD54 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="514"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="546"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="562"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="815" mass="91288" checksum="8C748FF1F66AE698" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4T4</accession>
    <name>A0AAD9D4T4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016334</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000055">
        <property type="protein sequence ID" value="KAK1733003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4T4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="363"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="554" mass="60746" checksum="661258B1191B3563" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5V4</accession>
    <name>A0AAD9D5V4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Guanylate cyclase</fullName>
            <ecNumber evidence="10">4.6.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_015298</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.2" evidence="10"/>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1734040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5V4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004383">
        <property type="term" value="F:guanylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001653">
        <property type="term" value="F:peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007168">
        <property type="term" value="P:receptor guanylyl cyclase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1230:FF:000059">
        <property type="entry name" value="Guanylate cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050401">
        <property type="entry name" value="Cyclic_nucleotide_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920:SF335">
        <property type="entry name" value="GUANYLATE CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920">
        <property type="entry name" value="GUANYLYL CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="514"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="9">
        <location>
            <begin position="574"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="21"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="54"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="101"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1734040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="917" mass="101689" checksum="97F48775BBC20389" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D668</accession>
    <name>A0AAD9D668_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">SLC41A/MgtE integral membrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_013926</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC41A transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D668"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="SLC41 divalent cation transporters, integral membrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006667">
        <property type="entry name" value="SLC41_membr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036739">
        <property type="entry name" value="SLC41_membr_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41394">
        <property type="entry name" value="MAGNESIUM TRANSPORTER MGTE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41394:SF5">
        <property type="entry name" value="SLC41A_MGTE INTEGRAL MEMBRANE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01769">
        <property type="entry name" value="MgtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161093">
        <property type="entry name" value="MgtE membrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="SLC41A/MgtE integral membrane" evidence="9">
        <location>
            <begin position="25"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1735312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="140" mass="14960" checksum="83234F3827864B7F" modified="2024-05-29" version="1">MISGGSDRLCGLIGRRKYTALISLLPIISAVSGNVGLQASTLTTRAISHSQVCVDNYSAWLKKEVTAAMYLGCAMGLISSSIAFCMGGFSVPFALSIFTAQWIGIFTAGVTGTLAPLLFTFIFERDSGKWEVHLKPQCKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D686</accession>
    <name>A0AAD9D686_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013804</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.150">
        <property type="entry name" value="Voltage-dependent anion channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038665">
        <property type="entry name" value="Voltage-dep_anion_channel_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="896"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="963"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="997"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1020"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1077"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1108"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1148"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1227"/>
            <end position="1250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="155"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="251"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="430"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="462"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="486"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="502"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="519"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="593"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="613"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="626"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="663"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="748"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="764"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="799"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="834"/>
            <end position="850"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1368" mass="151050" checksum="4B5E315009F489D8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6P2</accession>
    <name>A0AAD9D6P2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ribose-5-phosphate isomerase</fullName>
            <ecNumber evidence="4">5.3.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_014691</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14657"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="EC" id="5.3.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ribose 5-phosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.6" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6P2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004751">
        <property type="term" value="F:ribose-5-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009052">
        <property type="term" value="P:pentose-phosphate shunt, non-oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01398">
        <property type="entry name" value="RPI_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1360:FF:000001">
        <property type="entry name" value="Ribose-5-phosphate isomerase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00170">
        <property type="entry name" value="Rib_5P_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050262">
        <property type="entry name" value="Ribose-5P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020672">
        <property type="entry name" value="Ribose5P_isomerase_typA_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004788">
        <property type="entry name" value="Ribose5P_isomerase_type_A"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001924">
        <property type="entry name" value="PRK00702.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00021">
        <property type="entry name" value="rpiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43748">
        <property type="entry name" value="RIBOSE-5-PHOSPHATE ISOMERASE 3, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43748:SF3">
        <property type="entry name" value="RIBOSE-5-PHOSPHATE ISOMERASE 3, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06026">
        <property type="entry name" value="Rib_5-P_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75445">
        <property type="entry name" value="D-ribose-5-phosphate isomerase (RpiA), lid domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1734818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="293" mass="31267" checksum="8DA92D752A5AD2C1" modified="2024-05-29" version="1" fragment="single">NIYPPHIKQHHHHNLHHKMTSQEELKKQTGYKSVDDYVSSGMVVGLGTGSTAYYAVERLGQKLKSGELKDIVAIPTSIRTKEQAESLGIPLVTLDTHSKLDVAIDGADNVDPGFNLVKGGGGALLREKMVELAADKFIVIVDESKLCGGLGPTFPIPVEITPFCHEHTIRTIAALPSCEGCKAVLRMGSSSNNKVDGDEIAVTDNGNYIVDLHFAEAIKNVPKMAADLKALCGVVDHGLFCGMTTAVLCAGADGVTVTAPEKKNKAEKIVKNMAFLSAAVGLLAVSTMIIRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D712</accession>
    <name>A0AAD9D712_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Chlorophyll a-b binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_014214</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated. Energy is transferred from the carotenoid and chlorophyll C (or B) to chlorophyll A and the photosynthetic reaction centers where it is used to synthesize ATP and reducing power.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fucoxanthin chlorophyll protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D712"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030076">
        <property type="term" value="C:light-harvesting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3460.10:FF:000019">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="8" id="KW-0157">Chromophore</keyword>
    <keyword evidence="7" id="KW-0437">Light-harvesting polypeptide</keyword>
    <keyword evidence="5" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042156933" evidence="9">
        <location>
            <begin position="26"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1735148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="250" mass="26997" checksum="A4F5E11B2F6BD1D9" modified="2024-05-29" version="1">MVSISLQKITMKLALISILAGSAAAFAPAPTARTSVAQNAALDDLKSIAEKSNPVLKFYDPLELSSTTIWGNSNDDTIAFLRHSEIKHGRVAMAAFVGYIVQSNGIHWPFPIDFAGNPYPYAAGSPPEQWDALSDAAKWQIILFVGFLEWFSEAAGTHYMRGGVPGAYPKFSDHKVIPHPVPFNLFDPFGFSGGKSAEAKEKGLIKELNNGRLAMIGILGFISEQRVEGSVPLLKGLVSHYDGETMAPFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7C2</accession>
    <name>A0AAD9D7C2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha</fullName>
            <ecNumber evidence="4">2.5.1.58</ecNumber>
            <ecNumber evidence="3">2.5.1.59</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">CAAX farnesyltransferase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">FTase-alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Ras proteins prenyltransferase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Type I protein geranyl-geranyltransferase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_013733</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein prenyltransferase subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.58" evidence="4"/>
    <dbReference type="EC" id="2.5.1.59" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7C2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005953">
        <property type="term" value="C:CAAX-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005965">
        <property type="term" value="C:protein farnesyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004662">
        <property type="term" value="F:CAAX-protein geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004660">
        <property type="term" value="F:protein farnesyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.120">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002088">
        <property type="entry name" value="Prenyl_trans_a"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129:SF1">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE_GERANYLGERANYLTRANSFERASE TYPE-1 SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01239">
        <property type="entry name" value="PPTA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48439">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51147">
        <property type="entry name" value="PFTA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00040965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1735570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="354" mass="40567" checksum="D914545A07EC7D9B" modified="2024-05-29" version="1">MNIPDVFSDIDPISQSDGPEPACAITYTPEFVEAHDYLRAVLKADERSERAFALTTICLKFNPANYTCWHFRRRCLVSLCTPTDSDARATVDVERIDTDLEFADKLGGTNPKNYQLWYHRRALLEIRFKGDERIQVAQKELGYVDKILGDDNKNYHAWSHRQWIIRTINQPQLWSAEIEYSHSKILLDPRNNSAWNQRWFATHEGEIAANSGMKLGKLSFEKAEEEANYAVCGAQVDPFNESPWRYLIGVLMEQCRWVQREEGADDKDKVNGLLRDCVAKIKDMNDSPTEDYPAGPCVSLMSALVDLLETVGDKTSLEEAKNMMGELVVEDPVRRKYWHKRQSTVLVLLGKVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7K2</accession>
    <name>A0AAD9D7K2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_013516</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7K2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="303"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="668"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="306"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="687"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1735810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="846" mass="94917" checksum="7C8C66741854CD44" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8L0</accession>
    <name>A0AAD9D8L0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8L0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="92" mass="10133" checksum="B16B004AF087ED6E" modified="2024-05-29" version="1">MSPLARGLCRGLKLSQNIATRQPILRQTVVRNMSEGSRLHSTDIAFKPAESGWGGGGKYANNFDTIFSSKKKQDKNDKEGAAKKNNDHQSDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9W0</accession>
    <name>A0AAD9D9W0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elongation of fatty acids protein</fullName>
            <ecNumber evidence="10">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_010923</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>an acyl-CoA + malonyl-CoA + H(+) = a 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:50252"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:50253"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="10"/>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9W0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034625">
        <property type="term" value="P:fatty acid elongation, monounsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034626">
        <property type="term" value="P:fatty acid elongation, polyunsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019367">
        <property type="term" value="P:fatty acid elongation, saturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF126">
        <property type="entry name" value="ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="269"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1738254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="355" mass="39869" checksum="A60B6A5869E1C524" modified="2024-05-29" version="1">MCRRTPSTAAASDKTPSTLARFTTASILVAVLSVWGYFAYPPRDATPGLTTEMQSYKVPLALTAFYLVSLPTLKWFTETYLAPKYDMKLLLTESMIIYNVAQVFLNGWMVYAIIDALVYRGHPFIGSRSLTGVAISSGSSYAVWVHYCDKYLEFFDTYFMILRGNMKQVSFLHIYHHTTIAWAWWIAITYSPGGDVYFGALLNSIIHVMMYAYYALALMKVQCPWKRFLTQAQLLQFTSVVVYTGFTGYTHYTKLPHEAIAGEQPSIQEYFMCCGVQVFEMVSLFVLFSIFYKKSYSKKNKEAKAKEDDQCQKAMGEISIAAKEVAGHAAKDAGKVLASASKVVKRTGASSINAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DA09</accession>
    <name>A0AAD9DA09_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Trypsin-like serine protease</fullName>
            <ecNumber evidence="7">3.4.21.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_010937</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DA09"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000002">
        <property type="entry name" value="Transmembrane protease serine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF91">
        <property type="entry name" value="AT26814P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="Peptidase S1" evidence="6">
        <location>
            <begin position="67"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="297"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="297"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1738268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="493" mass="54158" checksum="8EDF62275830591B" modified="2024-05-29" version="1">MKLLRIIASSSIAAASAAGLRNSNSRDLGLVFDTEETAAFDTARVTSAIETADSGPAATNSFKEMRIIGGETADKDEFGYTVSLEDDIGHFCGGTLVRRDIVISAAHCAGGPMWARVGAHNIRWNEGEKIKVKKEIKSNKYNPSNTDYDFMILVLEDPAPADVPLAKLHDGSDALQDNDSLTVIGWGNMATNGWDMPDEKQHVEVKYVPNNDCNSANSYNGEITNSMLCAGETSGGQDACQGDSGGPLMRLGSGNQPDELVGVVSWGYGCGDRKYPGVYSRITEVLTWIENTIESESQFSDSDSDSSPTTTTATSTGSSSGEPSTFVNSNWREVFSEDFTNDFGKNGMEKGGTHARQYKKAFGRMGIARIQHGKGKKSSITTKKISARRSVAHQEDRGKQRSTDWKITFIFQGKGMEENEDRFCVKFQEDKKDWEDARCYMSGEDFYNGKWVTETLIIGVSDTAEDVKFRFECHGDTRTDDVLFDKIIIEVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAD6</accession>
    <name>A0AAD9DAD6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mechanosensitive ion channel family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_009121</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAD6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_beta-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30566:SF5">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30566">
        <property type="entry name" value="YNAI-RELATED MECHANOSENSITIVE ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Mechanosensitive ion channel MscS" evidence="6">
        <location>
            <begin position="286"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1740171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="457" mass="50574" checksum="885AE7B74C39412D" modified="2024-05-29" version="1">MSIRVLMLLRRFLGVGTNTNLGALHHSLKTKCCLENMGKYQAVKDSALAGKVTSAVASSALAGKITSICQVFVLSRDDIHQILTNVSEVIHAFDLSVLFIFGWMFVPAMGVVYAVLNEGKGKIKRVASRTELKKNTSAVDEQDEIDCSYESSYIYQFAVHVSQMAKLALLVYLCDIVVVALATIGYKAEEWGNVSNLFAKVLYTSWIAARIQSFKTHFLSRFMRKCPEECDKVLMVNRILDLTVLALLVVKIMGYFAMETGVALGSIAAFGTTSTLMISFASQELAKGVANGIEMAASDRFFEGDNVHFGDGTQGYIVKLGFLRTKVRKYDGAVLDVPNTQLGGQRLINVSKTKTCQVLTKIRFSYDDIQRIPDALEICKDEIKKACPKLIIDGKPFRAMISSFETQFVEVTFNTNFSLPPTGEGFWANRQEVFLAIDRGVKKAGLNYARPFDPAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAL6</accession>
    <name>A0AAD9DAL6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA replication licensing factor MCM2</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">QTG54_010810</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAL6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000138">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008045">
        <property type="entry name" value="MCM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059098">
        <property type="entry name" value="WHD_MCM2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF44">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12619">
        <property type="entry name" value="MCM2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23669">
        <property type="entry name" value="WHD_MCM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01658">
        <property type="entry name" value="MCMPROTEIN2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0347">Helicase</keyword>
    <keyword evidence="9 18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="17">
        <location>
            <begin position="675"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="298"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="89"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="128"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="203"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="300"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="313"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1738780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1115" mass="125443" checksum="328A2B7392B3BC4D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAT9</accession>
    <name>A0AAD9DAT9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyltransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_010336</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAT9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF35">
        <property type="entry name" value="PROTEIN O-GLUCOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
        <property type="entry name" value="Glyco_transf_90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00672">
        <property type="entry name" value="CAP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="3">
        <location>
            <begin position="391"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1739020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="638" mass="74126" checksum="D8F7E7FD41F345BD" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBB3</accession>
    <name>A0AAD9DBB3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein tyrosine kinase</fullName>
            <ecNumber evidence="3">2.7.10.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010073</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.10.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBB3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="219"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="515"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="523"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="542" mass="61692" checksum="79FA0A11CB75D32D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBX4</accession>
    <name>A0AAD9DBX4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DNA photo-lyase</fullName>
            <ecNumber evidence="9">4.1.99.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_007275</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="4">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA photolyase class-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.-" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBX4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003904">
        <property type="term" value="F:deoxyribodipyrimidine photo-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032922">
        <property type="term" value="P:circadian regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043153">
        <property type="term" value="P:entrainment of circadian clock by photoperiod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.579.10">
        <property type="entry name" value="DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="CRYPTOCHROME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455:SF9">
        <property type="entry name" value="CRYPTOCHROME CIRCADIAN CLOCK 5 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="Cryptochrome/photolyase FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="Cryptochrome/photolyase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0274">FAD</keyword>
    <keyword evidence="2 4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042067320" evidence="7">
        <location>
            <begin position="25"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="8">
        <location>
            <begin position="63"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="598"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="618"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="344"/>
            <end position="348"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="491"/>
            <end position="493"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="5">
        <location>
            <position position="424"/>
        </location>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="5">
        <location>
            <position position="478"/>
        </location>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="5">
        <location>
            <position position="501"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602081-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602081-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1741702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="631" mass="69732" checksum="AB1ADE5768C019D6" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DC31</accession>
    <name>A0AAD9DC31_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin fusion degradation protein 1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008599</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DC31"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034098">
        <property type="term" value="C:VCP-NPL4-UFD1 AAA ATPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01767">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.50">
        <property type="entry name" value="Ubiquitin fusion degradation protein UFD1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004854">
        <property type="entry name" value="Ufd1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042299">
        <property type="entry name" value="Ufd1-like_Nn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055418">
        <property type="entry name" value="UFD1_N2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555">
        <property type="entry name" value="UBIQUITIN FUSION DEGRADATON PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555:SF13">
        <property type="entry name" value="UBIQUITIN RECOGNITION FACTOR IN ER-ASSOCIATED DEGRADATION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24842">
        <property type="entry name" value="UFD1_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBX" evidence="2">
        <location>
            <begin position="538"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="462"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="204"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="621" mass="67299" checksum="718FAA7159E1DF1D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCK0</accession>
    <name>A0AAD9DCK0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008206</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCK0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042260602" evidence="1">
        <location>
            <begin position="34"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="156" mass="17328" checksum="9F5D7BA89C8CABCA" modified="2024-05-29" version="1">MVKMTRRRYQGNNGWMIVASISLFLCGVAVVLAIGTDDADNHHPTNEKICDSRFVPSKVDTSLFVGGEATAQAYKPNAPVKTHVCEESSSNGNNQLHKAAHWSFWRSDYKDNVPIFIKANLFSCNGGVLLQGRTKKSPWKCGSHVPMGHIHRYARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCN5</accession>
    <name>A0AAD9DCN5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006303</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCN5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053025">
        <property type="entry name" value="Mito_ATP_Synthase-Asso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44873">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 30, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44873:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 30, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042079608" description="J domain-containing protein" evidence="2">
        <location>
            <begin position="31"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="256"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1742706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="384" mass="41550" checksum="D1D067D22198F1F6" modified="2024-05-29" version="1">MSFSIAMGNTLLLAFFSSTLLLQNVITVHSFTTTPTKSCRASMPIIPSAAATTTTLAAGGGMGMATKPKGKKKGGKKDKKKSTSQPFDVSAALIKNEKLYEELMAENTKALMNDDDYGDIDLTTEYIIAARAKPDGSSPSSTFVGASDWVPVAQLCIVRSISQDDNKDDDHESVMESTLTAAVSYFCREINYLGCLSAPSAFKSLPRNNVEYGIEPIESFMKHVYEDVIEGKNSNNGSSNGSSSSSSSSNGMSKAQAREILELDAGITDTAMIKTAYKKQSFKYHPDRISEEDREALSERFYDIKQAYETLNSGVRNKVVNGSQHSWYASLGGRDRNNFLGPISLLSMEKAGALCNKAFKSAVVGIDPDLTMAFVARNQSAARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DD52</accession>
    <name>A0AAD9DD52_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Guanylate cyclase</fullName>
            <ecNumber evidence="14">4.6.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_007853</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.2" evidence="14"/>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DD52"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004383">
        <property type="term" value="F:guanylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001653">
        <property type="term" value="F:peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007168">
        <property type="term" value="P:receptor guanylyl cyclase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1230:FF:000036">
        <property type="entry name" value="Adenylate/guanylate cyclase catalytic domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.20:FF:000060">
        <property type="entry name" value="Sensor protein FixL"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018297">
        <property type="entry name" value="A/G_cyclase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050401">
        <property type="entry name" value="Cyclic_nucleotide_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920:SF335">
        <property type="entry name" value="GUANYLATE CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920">
        <property type="entry name" value="GUANYLYL CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00452">
        <property type="entry name" value="GUANYLATE_CYCLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 10 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="PAS" evidence="12">
        <location>
            <begin position="187"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="12">
        <location>
            <begin position="335"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="12">
        <location>
            <begin position="462"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="13">
        <location>
            <begin position="625"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="808"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1741375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="832" mass="92873" checksum="A7C7E323B20E8A89" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDL9</accession>
    <name>A0AAD9DDL9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">BEACH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006063</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDL9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06071">
        <property type="entry name" value="Beach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1540.10">
        <property type="entry name" value="BEACH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000409">
        <property type="entry name" value="BEACH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036372">
        <property type="entry name" value="BEACH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050865">
        <property type="entry name" value="BEACH_Domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057496">
        <property type="entry name" value="FAN-like_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023362">
        <property type="entry name" value="PH-BEACH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13743">
        <property type="entry name" value="BEIGE/BEACH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13743:SF123">
        <property type="entry name" value="PROTEIN FAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02138">
        <property type="entry name" value="Beach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25400">
        <property type="entry name" value="PH_FAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01026">
        <property type="entry name" value="Beach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81837">
        <property type="entry name" value="BEACH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50197">
        <property type="entry name" value="BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51783">
        <property type="entry name" value="PH_BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BEACH-type PH" evidence="3">
        <location>
            <begin position="285"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="BEACH" evidence="2">
        <location>
            <begin position="413"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="738"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1743442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="767" mass="85404" checksum="B32C4D82F99393A8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DE51</accession>
    <name>A0AAD9DE51_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Coronin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_006943</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat coronin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DE51"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015505">
        <property type="entry name" value="Coronin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015048">
        <property type="entry name" value="DUF1899"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10856">
        <property type="entry name" value="CORONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10856:SF0">
        <property type="entry name" value="CORONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08953">
        <property type="entry name" value="DUF1899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01166">
        <property type="entry name" value="DUF1899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="DUF1899" evidence="5">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="75"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="135"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU280818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1742378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="258" mass="28739" checksum="2E14A227D42EF6EA" modified="2024-05-29" version="1">MFKIRTSKYRHVFCDAPKTESTHTGFRLSTVTGDQQYIKASTKYFAVALFGGGGAVYVGRHDRPGRFVPGHTPTLHGHAGAILDFEWNPFDDTMLATASEDTTIKLWSIPEDWEPIAANGQSKKGTDIEESLVDLVGHAKKVNLMRFHPTAANVLASSSSDYTVKLWDIETSQELSTFEEMQDLCQDIVWDYKGDSYATSCKDKSVRFIDARSSKVGKMIKMAHDGVKGVKVCYLGQSGKFLRRVILEQLVGKLRFGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEG3</accession>
    <name>A0AAD9DEG3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006275</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="2">
        <location>
            <begin position="397"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1337" mass="149409" checksum="C3BF5A4B783926F2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFB6</accession>
    <name>A0AAD9DFB6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sel1-like repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_005671</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFB6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="8">
        <location>
            <begin position="12"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="142"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="553"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="8">
        <location>
            <begin position="798"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="863"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1066"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1066"/>
            <end position="1081"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1744074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1117" mass="124250" checksum="7E898F4EBFD8C1E8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFE6</accession>
    <name>A0AAD9DFE6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GST N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005402</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFE6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="31"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="218" mass="24438" checksum="82201E1331F31DD8" modified="2024-05-29" version="1">MIILFPLSFVSRSHSPLVSHILSANMIDADVEYTFHCYDHCPFGNRVAFLMDHFGIKYKKVVYGYGSGALPKDCEGKGYDGDLNPRRLTGKKQLPVLEGAGVPIVKPDDIGMAESLEICSFLIGRHQLVCPCATGRPDIKSIESYLLDKKVMNPLKLTRLTKIPVADWADPRDISYHLWKHQKKGDILEYSSEEDAEAIKDLNSKLIEFAARSRVISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFU9</accession>
    <name>A0AAD9DFU9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004833</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFU9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="308"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="364"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="425"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="517" mass="58261" checksum="728AFE1040B19327" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGS1</accession>
    <name>A0AAD9DGS1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGS1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="137" mass="14505" checksum="C96957A9DCA381F0" modified="2024-05-29" version="1">MFAQRLRPAERSVSITKKAPVLPSAAAGKKIVAGKKRPPSPSVEEKQPKRVSIKGPSRSSSTASKSVTSISPSAAGKVAPKTKSGGKKMAPKQSKITVTDPNAPIPMHVAIASIKESYPGRRQIKDLEGFEAECLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHJ4</accession>
    <name>A0AAD9DHJ4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002009</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1748046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHJ4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="303"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="74"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="91"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="442" mass="49374" checksum="78E172D2C6D1FCFC" modified="2024-05-29" version="1">MPLRSLNRKKKKEQPQLKENKIKPCPSSPVNLSSASSLTQTSSYSSCTNSLASSTQTRKSAEPPGWVHNPPPRTLNNEEISANNGLLLKENNAPNNNNNYPPSNTPRRQWTHQRTVPSPVCIRSSPQPPQSNTTMPSSYQRQNIMTHTMSENTIQMTYSESSGSEGSSISSLGLNAESNDEQLLDFERYECVEEIDRMTKSKDWTVNNFDLCNGGYGGGQQSLKNLPTSTMSSESVDIESQISFPQTHLREECTSVTMDSAEQRMNCAAPTALLDMNRMQDIYGSMMVAFRKKIMAELRDEMQKEMQHQLFALKNELSEMNTRLTNLEKNQTSAPNLQQGFETNILKEITSKVLNDKEQQQKQLEAMLDAKLAKAMAGVKVEMNLAVHEMKKEGDRLSKMTVCAESPPHGKKSSNKVSWNCTSTKGKEEGLGCECNQLIVTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHT3</accession>
    <name>A0AAD9DHT3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alkaline phosphatase family protein</fullName>
            <ecNumber evidence="6">3.1.6.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_003216</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHT3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047115">
        <property type="entry name" value="ARSB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10342">
        <property type="entry name" value="ARYLSULFATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10342:SF274">
        <property type="entry name" value="ARYLSULFATASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase N-terminal" evidence="5">
        <location>
            <begin position="86"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1746609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="542" mass="61087" checksum="957542ED99E18FA3" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIH8</accession>
    <name>A0AAD9DIH8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_001337</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIH8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="118" mass="12796" checksum="3DD259A9D86C177B" modified="2024-05-29" version="1">MGLAADAKAGQKSCSTIVTQMVSSTIESRSASYQMGRQRVDVELARKCTFTQALWRAARFIGCGESVKSMGEGKMCRVQVCRYTRTGNCGMGSGVNWKGKMMEDFSNCGHACPPEGCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIU6</accession>
    <name>A0AAD9DIU6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein kinase family protein</fullName>
            <ecNumber evidence="6">2.7.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_002492</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.-.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIU6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF24">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CHK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042070266" evidence="4">
        <location>
            <begin position="23"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="62"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1747148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="540" mass="60087" checksum="6EFCF24B9DF2C315" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DK14</accession>
    <name>A0AAD9DK14_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000544</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DK14"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="140"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="332" mass="37364" checksum="23F61439A77E5288" modified="2024-05-29" version="1">MWNVCRSSQDWTMVYPTLFEHALPNTVGNNNSKESIQVLVSPLRSAGPVERDVDELVKRSYREKQQLQMKEHECVEKKMPGRTKSDANYPQSKISPTLCEGDEWQQEASIDDEGGKFSLGLRLSASLSNRSRENRDDDYPGSSSSFSYSHDGSVCGETNDDSNLNRSLSLTNAMSFTRQLSVPISPPRNKADSCDEFDRPLIRLKYGDRVQVVSMDSRGWVKLARGYGYIRLQNDKQLVKVGGTSDRACQIEATLHELSIERDRLKNEQTKLERLSAGLMIDLQSTLLTSDDHVICSAPEGMPRIDSDLELSTGQQEVKFGRFDVKSKSPNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1GZM9</accession>
    <name>A0A8K1GZM9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Photosystem I reaction center subunit VIII</fullName>
            <shortName evidence="11">PSI-I</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11 13" type="primary">psaI</name>
        <name evidence="12" type="ORF">QTG54_017202</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="13"/>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2021" name="Front. Plant Sci." volume="0" first="0" last="0">
            <title>Chloroplast Genomes for Five Skeletonema Species: Comparative and Phylogenetic Analysis.</title>
            <authorList>
                <person name="Liu S."/>
                <person name="Xu Q."/>
                <person name="Liu K."/>
                <person name="Zhao Y."/>
                <person name="Chen N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CNS00100</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">May help in the organization of the PsaL subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Plastid thylakoid membrane</location>
            <topology evidence="10">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Plastid</location>
            <location evidence="11">Chloroplast thylakoid membrane</location>
            <topology evidence="11">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the PsaI family.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MW679506">
        <property type="protein sequence ID" value="UAM91403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_010200915.1">
        <property type="nucleotide sequence ID" value="NC_058701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1GZM9"/>
    <dbReference type="SMR" id="A0A8K1GZM9"/>
    <dbReference type="GeneID" id="68638047"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00431">
        <property type="entry name" value="PSI_PsaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001302">
        <property type="entry name" value="PSI_PsaI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036357">
        <property type="entry name" value="PSI_PsaI_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03052">
        <property type="entry name" value="PS_I_psaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35775">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35775:SF2">
        <property type="entry name" value="PHOTOSYSTEM I REACTION CENTER SUBUNIT VIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00796">
        <property type="entry name" value="PSI_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81540">
        <property type="entry name" value="Subunit VIII of photosystem I reaction centre, PsaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 11" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="6 11" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="13" id="KW-0934">Plastid</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00046266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1732159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="UAM91403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="36" mass="3919" checksum="1DD9D6E0DD95976B" modified="2022-08-03" version="1">MAAAFLPSILVPLVGLIFPAFSMALFFLYSQKDDIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1LV38</accession>
    <name>A0A8K1LV38_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hypothetical chloroplast RF41</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ycf41</name>
        <name evidence="3" type="ORF">QTG54_017183</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="4"/>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2021" name="Front. Plant Sci." volume="0" first="0" last="0">
            <title>Chloroplast Genomes for Five Skeletonema Species: Comparative and Phylogenetic Analysis.</title>
            <authorList>
                <person name="Liu S."/>
                <person name="Xu Q."/>
                <person name="Liu K."/>
                <person name="Zhao Y."/>
                <person name="Chen N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CNS00100</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MW679506">
        <property type="protein sequence ID" value="UAM91454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_010200896.1">
        <property type="nucleotide sequence ID" value="NC_058701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1LV38"/>
    <dbReference type="GeneID" id="68638023"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="UAM91454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="104" mass="11916" checksum="37AB54B957984BCA" modified="2022-08-03" version="1">MNYSIFTVKIIKNCGQSFFTDGTSLTELVVQLPQIRKNNVKTILQLSVWGNLSYDVARYYQADDYIIIEGYISVRNIDVNQTLNSADKQVEISVFKVYPLLLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRY5</accession>
    <name>A0AAD8XRY5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_016928</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000068">
        <property type="protein sequence ID" value="KAK1732393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRY5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06171">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050239">
        <property type="entry name" value="Sigma-70_RNA_pol_init_factors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30603">
        <property type="entry name" value="RNA POLYMERASE SIGMA FACTOR RPO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30603:SF47">
        <property type="entry name" value="RNA POLYMERASE SIGMA FACTOR SIGD, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="Sigma2 domain of RNA polymerase sigma factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="Sigma3 and sigma4 domains of RNA polymerase sigma factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA polymerase sigma-70 region 2" evidence="7">
        <location>
            <begin position="508"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="94"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="308"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="354"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="112"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="158"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="314"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="325"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="388"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1732393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="752" mass="82522" checksum="88810DE657C41F5F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSB0</accession>
    <name>A0AAD8XSB0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016459</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSB0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="600" mass="66107" checksum="7667013C44D13BAA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSE0</accession>
    <name>A0AAD8XSE0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MAP3K-like serine/threonine kinase</fullName>
            <ecNumber evidence="3">2.7.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016297</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000055">
        <property type="protein sequence ID" value="KAK1732966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSE0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="115"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="541" mass="60941" checksum="B65E4E8B0AC31ED4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSH9</accession>
    <name>A0AAD8XSH9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ankyrin repeat and MYND domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_016357</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000055">
        <property type="protein sequence ID" value="KAK1733026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSH9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24173">
        <property type="entry name" value="ANKYRIN REPEAT CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24173:SF74">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="230"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="265"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="8">
        <location>
            <begin position="333"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1733026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="376" mass="42350" checksum="20E38C87AABBFB81" modified="2024-05-29" version="1">MKGNGMLMGASMAFLPPEMRPVPSRPRKVLFQTRGEVEMLRDELKEMGIDEVDVAEQSLIQSCEIQASSTDMPSPDGASIEEIMHDPRAMMAHRIIEQTEGPYVSEERVSLGGWSPPNEPGDFPLCWYARPPSDPTSYRPTTLCGWRTNLERAVLREDSDNVKRIVSKYNSNHVREYVECRMLLTKMAQRGMVNACRLLIVECGASVEGAQAPDAKGWWKGIQNNSGNYQDLTPLHQAARNGKLETVRLLLEHGANVNQIDRSEIRGSPLHHAVSMGEIDCVKLLCENGADHTYAGFGGEALDISEMVVGGDVFKQRVQTKVDQILREYDARCSYCRKSHPLKQCPCKKERYCDASCQRRRWKLHKKYHNEIVGGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSW7</accession>
    <name>A0AAD8XSW7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Leucine-rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_016093</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000052">
        <property type="protein sequence ID" value="KAK1733236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSW7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="247" mass="28080" checksum="7A3F7CB83D91F53E" modified="2024-05-29" version="1">MMAAEEYYIYTGGVVPRHVTRVRIDKSITVIPARAFQGHPNITELDCHDKVEKVEESAFYLCRSLRRVIMPGVKVVDQWAFWKCEALTIVECGKLERIRGCAFSSCISLRNINLPSIKIVEGSAFCWCKALMTVKFGDKLKTLNGRALYGCRALERIAIPLKDGMITHDNIITGCEKMKHVDLVEEELHETIAALLLEEWKKDMRRKIDALNQILDSSHYTCRKGRGCGGEGRCDTNLDHKCSTQYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUL4</accession>
    <name>A0AAD8XUL4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heat shock factor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_015583</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000045">
        <property type="protein sequence ID" value="KAK1733728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUL4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000479">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF206">
        <property type="entry name" value="HSF-TYPE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="6">
        <location>
            <begin position="77"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="203"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="203"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1733728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="438" mass="50052" checksum="3A453EB1EAAFAF46" modified="2024-05-29" version="1">MNQRSESSWSFPSAASKFSKIDEKLVTQHLYYHSQYGLKVTAMPTSDDCFPRFADHTYREYSTYIERGGAIDKHKKSDRNFPARLHAMLSDEQYSHIISWMPHGRAWKVINKELLMEEAIPKFFGQSKFASFSRQLSGWGFTRLNKAGRDFGCYYHECFLRGHPRLTVLMRRVSPGQGKAAPNIYAEPDFYLIAKRYPLEKSADVPDKEKNEASKHEDVPLAAKEAAAPDMKESISTHQWDPYDQQNAAHPTREAAALSCYDSSIHFSKVSSQSDSFAGVDVNRGDDKKEDKYQEAIKYDPFSVSYHHLDPQGYSMHQAHHEAVMSRYYGSMAAAGYYYPKSYRSHLHDDDMFPYDYRYNNPYSCYSNYHSAQGLAQAQGYAQAQGANTAIQPHYPAQGACNHNLPLPLPEFSQLEHGQELKSVFNEDEKESDSKPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV71</accession>
    <name>A0AAD8XV71_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000040">
        <property type="protein sequence ID" value="KAK1734288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV71"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="521"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="623"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="623"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="820"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="820" mass="93904" checksum="49DCA28DC43A7AFB" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWG4</accession>
    <name>A0AAD8XWG4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heat shock factor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_014225</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWG4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000479">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF206">
        <property type="entry name" value="HSF-TYPE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="6">
        <location>
            <begin position="96"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="199"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="229"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1735159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="342" mass="38640" checksum="346CCF9CC45F7B62" modified="2024-05-29" version="1">MRTSVNEHRVSRFKNTLVWYSDAIAGHLLSLQYITIPEKLTNMLAYRCTTSTNNSVTQPAIAFNSIYNKSTNLAMTNTAPIGRSPSRSNSSTGLARSDKFPSKLYEMLESVDCLGLSHTASWLPHGRSFQVKDPTQFMDLVVPKFFKATKYRSFQRQLNLWGFSRIVKGQEHACWHHEYFVRGRPELLSKISRTRVKVKGREATQAADTRKEAPMQVPSEDSSEGASDYNEDDDVYEEDASVTNSTRHFSYTSSYVAPAPFKDEVFDEKLNAKFFERDPSQNRNSGFANVDQMCLEPLPIDSAGILDSPGNRNNCDLAEFGQLLGRFQEEEERAEASRRPGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWI2</accession>
    <name>A0AAD8XWI2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">tRNA (Guanine-N(7)-)-methyltransferase non-catalytic subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_014655</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWI2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043527">
        <property type="term" value="C:tRNA methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036265">
        <property type="term" value="P:RNA (guanine-N7)-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028884">
        <property type="entry name" value="Trm82"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16288:SF0">
        <property type="entry name" value="TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT WDR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16288">
        <property type="entry name" value="WD40 REPEAT PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="231"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="43"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="282"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="477"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="43"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="56"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="284"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="302"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="500"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="516"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1734782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="531" mass="58357" checksum="C6FE29972203E4FD" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWV9</accession>
    <name>A0AAD8XWV9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histone deacetylase, class IV</fullName>
            <ecNumber evidence="4">3.5.1.98</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_014248</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141221">
        <property type="term" value="F:histone deacetylase activity, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040029">
        <property type="term" value="P:epigenetic regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09993">
        <property type="entry name" value="HDAC_classIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044150">
        <property type="entry name" value="HDAC_classIV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF19">
        <property type="entry name" value="HISTONE DEACETYLASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042086346" evidence="2">
        <location>
            <begin position="17"/>
            <end position="1910"/>
        </location>
    </feature>
    <feature type="domain" description="Histone deacetylase" evidence="3">
        <location>
            <begin position="169"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="Histone deacetylase" evidence="3">
        <location>
            <begin position="281"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1735182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1910" mass="221009" checksum="68C50B30F1928DD5" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XY81</accession>
    <name>A0AAD8XY81_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013608</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XY81"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35716">
        <property type="entry name" value="OS05G0574700 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="321" mass="36208" checksum="7936443B22467ECE" modified="2024-05-29" version="1">MSWLGKNTNWNRCDKQYDSYMDFSTISDNRQNVSFTSTTKDFATIIVAIVLVFLNNMTTCKQKLLLLAALLFTLMMVHSSNGFLGSSRSNSNNDKLMARRMRLVATNTPSSPMPGRSSCLYERRSYDDKSDEELFAALLVDKKSKARDATASPSSSLDSSRYAHLANITSPSPSIKPEDIIPLVMIALKNNDVPDKDAGIKLVWEFATDTTQYVFRNNRTEFIESCHETAEEFPTSFYGVAINGQSWKIETKVNRVGGESGWIATQVIKTVSSDGRLRRWQWELRKNKRPPCLGCWKIESIGSSDRNGDFEARDRGNGWSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYU2</accession>
    <name>A0AAD8XYU2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutaredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1735982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYU2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042033682" description="Glutaredoxin domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="162" mass="17951" checksum="6CDA2F1953503AFF" modified="2024-05-29" version="1">MRVALTFICSILTTARAFAPSRNAWSTGTALPAGLFDNIFKAKEQGNKVEKSIGNTTGANASFKKQLDGMMKKKKFSVLMISSSAKDCIKEKKILDEKRVKYKAIELNKEANAEAIRAEFGNGIWIRGKFIAGFNELNNLDKRGELDGLLKNVPKTTYTTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZ70</accession>
    <name>A0AAD8XZ70_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZ70"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="877" mass="97235" checksum="D36B554B28EE42F1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZ76</accession>
    <name>A0AAD8XZ76_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013018</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZ76"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="222" mass="25249" checksum="AA0B2A2B3A6BF65D" modified="2024-05-29" version="1">MQEESTSKTHQSYRSTPSTASSSNLSKSYLTLKQIEFPLFHQMIRSQVHKAIQPLNRRVITSLPAQSVLWDSEKLLKQDEEARKKAQYFFSHGVPNKAECKLLATLLQKHNTEIKSFPYLFFYEWSPSNMMGRGDAVFASGKGGLVVVEAKAKHATKHVTKQSLFYRQRLLEEYPHSSVSAAILTHRGFAWTQKESEQAENPVQLTSVLLPCGRRGIENLHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZH0</accession>
    <name>A0AAD8XZH0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyruvate dehydrogenase E2 component</fullName>
            <ecNumber evidence="2">2.3.1.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012813</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.12" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZH0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004742">
        <property type="term" value="F:dihydrolipoyllysine-residue acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:pyruvate decarboxylation to acetyl-CoA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045257">
        <property type="entry name" value="E2/Pdx1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151">
        <property type="entry name" value="DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151:SF90">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="2-oxoacid dehydrogenase acyltransferase catalytic" evidence="1">
        <location>
            <begin position="86"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="319" mass="33660" checksum="419153BD15278F56" modified="2024-05-29" version="1">MVLSTAVRLAASRPSGRSSLINFLGKDGWAARLSAPVPAPVAAPAATTVAASSAAAPAASVAAPQPVASPINVAPETVTTVPPSMYEDTPASNMRKIISRRLTESKATVPHFYTSIEIPLDSILSLRKVLAKEFDTKVSVNDFIIKASALALRDVPEVNGTYDVKSQSQRTFESVDISVAVATPTGLITPIVPSTQGLSLTDISAKVRDLATRARDNKLAPEEFQGGTFTISNLGMFGISEFSAVINPPQGAILAVGGGERKIVPGSVNVETGEKEKPRIQTTMTARLSADRRVVDEATAALFMGVLKEYMNQPKLMML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZS1</accession>
    <name>A0AAD8XZS1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA repair protein REV1</fullName>
            <ecNumber evidence="3">2.7.7.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012661</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZS1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017125">
        <property type="term" value="F:deoxycytidyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070987">
        <property type="term" value="P:error-free translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024728">
        <property type="entry name" value="PolY_HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45990">
        <property type="entry name" value="DNA REPAIR PROTEIN REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45990:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11798">
        <property type="entry name" value="IMS_HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="UmuC" evidence="2">
        <location>
            <begin position="149"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="386" mass="42783" checksum="BA9A5B44576749CD" modified="2024-05-29" version="1">MDSVEKQKLLPHADYLLKGVLDKNVFGSKKVKSYFAVQPKLTEEHASEGQADKRKCGEMTGEENCEQVVEKGPEKSVTGRPYRWQDKDPHEANHMFAGAKTVGNDPNFLDSYFSNSRLSYIGSFQQRVKSSGSAKGVASSVRAGCKKFVMLVDMDCFFASVVLRKYPQHRSKPVAIAHAHSNNQANNANSSSELSTCNYLARQKGVKKGMFLGDAIIKCPDLVVLPYDFEGFQEVSGIVADQLRLYAEQYNGCIEQVSCDEAYVEINVDPNDCNNDIYDFVKSLAEHIRVDIVKKTECTASIGIGPNKLLAKLAADKIKPNGCYVCRDWKELLGGLDLRDIPGVGWKSQKKLEPRGLRTVADVWDLNDEAETVLGEIIGLGNLKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZY8</accession>
    <name>A0AAD8XZY8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012981</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZY8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="165"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="441"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="653"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1116"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="701"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="775"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="849"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="990"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="464"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="496"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="524"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="653"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1140"/>
            <end position="1151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1151" mass="132025" checksum="BA75C7CD67E307CC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y032</accession>
    <name>A0AAD8Y032_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycolipid transfer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_013030</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y032"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902387">
        <property type="term" value="F:ceramide 1-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902388">
        <property type="term" value="F:ceramide 1-phosphate transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3520.10">
        <property type="entry name" value="Glycolipid transfer protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036497">
        <property type="entry name" value="GLTP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014830">
        <property type="entry name" value="Glycolipid_transfer_prot_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10219:SF43">
        <property type="entry name" value="GLYCOLIPID TRANSFER PROTEIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10219">
        <property type="entry name" value="GLYCOLIPID TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08718">
        <property type="entry name" value="GLTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110004">
        <property type="entry name" value="Glycolipid transfer protein, GLTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042263091" evidence="2">
        <location>
            <begin position="28"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="Glycolipid transfer protein" evidence="3">
        <location>
            <begin position="150"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1736430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="343" mass="38334" checksum="61945C746BCDB1AE" modified="2024-05-29" version="1">MRRNIRINNYVLIITALISIGLQFADASPLGFPPLPFIRGGSATTATKTRTTKQQHQRQRRQRKTGGPIPGPLKLVGNVKQGLDKIGGYIQNDWKKISKGMQTVQGNIGKFVVNIPKALPFLPPRKRQLKCSKLDDVCKTFSACLKGSEVDTAQLIKACRTHLIFMKSGGSSLRLVAKDLESNLQKAEKPFKKSPKQGKTLSSLLESEREAGIHQGNVLKEQSAAMGLLWIRRSLAFQLDLYSSLIAQNGPHPRDAAYEAYSKHLSPFHGWALRKVFPASLSQMPDRQAFIAKFGGVSLEELNDEYDREVVKKLKSLVAAWDPLLSTWEKDFARLDLEDMRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0H8</accession>
    <name>A0AAD8Y0H8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Rhodanese-related sulfurtransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_012799</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0H8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluA-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022111">
        <property type="entry name" value="Rhodanese_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020936">
        <property type="entry name" value="TrhO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040503">
        <property type="entry name" value="TRHO_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43268">
        <property type="entry name" value="THIOSULFATE SULFURTRANSFERASE/RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43268:SF6">
        <property type="entry name" value="THIOSULFATE SULFURTRANSFERASE_RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12368">
        <property type="entry name" value="Rhodanese_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17773">
        <property type="entry name" value="UPF0176_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="279"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="115"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1736777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="981" mass="108002" checksum="05C37855E76F12CF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0W5</accession>
    <name>A0AAD8Y0W5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">phosphoethanolamine N-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.103</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_011860</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N,N-dimethylethanolamine phosphate + S-adenosyl-L-methionine = phosphocholine + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25325"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58641"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:295975"/>
            <dbReference type="EC" id="2.1.1.103"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:25326"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>N-methylethanolamine phosphate + S-adenosyl-L-methionine = N,N-dimethylethanolamine phosphate + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25321"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57781"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58641"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.1.1.103"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:25322"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Phospholipid metabolism; phosphatidylcholine biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.103" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0W5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000234">
        <property type="term" value="F:phosphoethanolamine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44307">
        <property type="entry name" value="PHOSPHOETHANOLAMINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44307:SF2">
        <property type="entry name" value="PHOSPHOETHANOLAMINE METHYLTRANSFERASE ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1737574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="287" mass="31583" checksum="D7899E1AB6B44638" modified="2024-05-29" version="1">MSPSQDVPNDDAIKTMKLYTHVERIQREVKSRFGSEAIDPIALSEIDCMHYEGNDAIEDVIQAINLNSSSKVLDVGSGFGGVARVLSAQSKCTTVAMELQSDIHNCAEDLTKRCNLSDLVKHVEGDVLNYDLSKLGDGPSTFDGLVSFLVFLHIPDKLSLLNSCANMLKAGGTLFVEDYYRRSSFTDAELESLSTDVFCQDLPTQDEYIAALESAGFDNIQFIDKTKEWATFVKGRLAKFEGNKESFISSHGEPTYASLHYFYKSVVTLFVGGNLGGVRIIASKKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1L6</accession>
    <name>A0AAD8Y1L6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WRKY19-like zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011228</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1L6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056866">
        <property type="entry name" value="Znf_WRKY19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24906">
        <property type="entry name" value="Zf_WRKY19"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="407"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="434" mass="46971" checksum="3C53BD6CFD441CCC" modified="2024-05-29" version="1">MPTQGGNDDADQQLLGLDDFEFCQPVEATAETNNSDAGDGDGQQPKKKKQKISCSIDNCTNTAQSGGICLKHGGKYRNRYYCSVEGCTKYPKAGGVCKAHGAKVTRPLCQIEGCNNLETNKGVCIRHGAKVKLCRVDNCPKQALKGGVCWSHGAKDLKVKKKCSVENCETLAHKGGVCTKHGAKQCSVDDCTNQAKKGGVCYTHGATPVKKKLCSIGGCPNQAKVEGYCKRHKTLISKARKEATAVVEAPPGKLGLTLKIDPVYGGARITSIESDCKLKGQIEVGDRVTSIDDHVITQTADFGINSDKTRQFKIAVNNSLENVLFREHSDLGERLKASLSGRQISEMQSQIQRLVQAQEDSLSREAALKIQLERAAAKETALGAQLRDAKSRAKELKEENAVLKTSLAREKRRAKKCPNCAEKKLPEGDDNNLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1T7</accession>
    <name>A0AAD8Y1T7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA demethylase ALKBH9B-like protein</fullName>
            <ecNumber evidence="3">1.14.11.53</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011624</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.53" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1T7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990931">
        <property type="term" value="F:mRNA N6-methyladenosine dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044842">
        <property type="entry name" value="ALKBH9B/ALKBH10B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31447:SF23">
        <property type="entry name" value="2-OXOGLUTARATE AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31447">
        <property type="entry name" value="HYDROXYPROLINE-RICH GLYCOPROTEIN FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="2">
        <location>
            <begin position="143"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="331"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="387" mass="42192" checksum="1276979E8D212721" modified="2024-05-29" version="1">MPKSAASKSKQSSQPPPPSPHNKKKASGTTFSLLDKSKKNLDILQGLVLHKEVISSQFENELISFIQSQCTKGRSGQLKKPTYLRSAGARSQGNQREALQYGGFFDFNKARPGKRGLVPDFPPIVHRLVNHLIDEGYLDKEVRPDSCIINQYGKGDCIPPHVDHESYYRPISTLSLLGEEPMLVGTKFQTVKSCTWKPTVGTSVALPRRSLLLLGGNSGNVSKHCISSCRGERISITLRKQPGPDWRPSLDELAKSGGGGGGGGKKRKRDAAVTLTANDYNNDDDGGGGDGAKKKKKALSGSAKRRKKMMKLKGITTTLPESGQGDASVHQQQQQHQQQMTQSQSSSNGEKTSTKKKSSEKQAKRNARRLERKQKQATAGTKSKCNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2A6</accession>
    <name>A0AAD8Y2A6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011494</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2A6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="entry name" value="Intergrase catalytic core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="562" mass="62702" checksum="91FCBE0CDCBDE3B2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2C0</accession>
    <name>A0AAD8Y2C0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptide-methionine (R)-S-oxide reductase</fullName>
            <ecNumber evidence="4">1.8.4.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_011178</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MsrB Met sulfoxide reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.12" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2C0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033743">
        <property type="term" value="F:peptide-methionine (R)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.20">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028427">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002579">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10173">
        <property type="entry name" value="METHIONINE SULFOXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10173:SF57">
        <property type="entry name" value="PEPTIDE-METHIONINE (R)-S-OXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01641">
        <property type="entry name" value="SelR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51790">
        <property type="entry name" value="MSRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MsrB" evidence="3">
        <location>
            <begin position="74"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1737884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="232" mass="25113" checksum="018E99AA16282EC1" modified="2024-05-29" version="1">MDSIKSSLLIVGLLLSYGITMSSGLSTISRRRYLQWQTGGCIATASTTALSNPSVAQAANLKSRTEGYDVQHTEREWAYILSGAQYNILRKGGTERQKSSILNTYTTENVGSYVCAGCNTPLFTSADKFSSGTGWPSFSTALQGVEEEELDPIRATLDGKEVRCATCGGHLGDLFNDGWIYRGTSAAKTGKRYCIDGAALIFKPEDGGEDVFGDLPPPNRVIKYEQSMYRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2K6</accession>
    <name>A0AAD8Y2K6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Chromatin-remodeling complex ATPase</fullName>
            <ecNumber evidence="14">3.6.4.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_011313</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="14"/>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2K6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034728">
        <property type="term" value="P:nucleosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000082">
        <property type="entry name" value="ISWI chromatin remodeling complex ATPase ISW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000015">
        <property type="entry name" value="lymphoid-specific helicase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.30">
        <property type="entry name" value="ISWI, HAND domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036306">
        <property type="entry name" value="ISWI_HAND-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015195">
        <property type="entry name" value="SLIDE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623:SF49">
        <property type="entry name" value="SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09111">
        <property type="entry name" value="SLIDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101224">
        <property type="entry name" value="HAND domain of the nucleosome remodeling ATPase ISWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="200"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="501"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="13">
        <location>
            <begin position="873"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1082"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="801"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="16"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="138"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1082"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1103"/>
            <end position="1115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1738019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1139" mass="130596" checksum="76C28D87092DE668" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y354</accession>
    <name>A0AAD8Y354_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pseudouridylate synthase RPUSD4, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">RNA pseudouridylate synthase domain-containing protein 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_011451</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a uridine in mRNA = a pseudouridine in mRNA</text>
            <dbReference type="Rhea" id="RHEA:56644"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:14659"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a uridine in tRNA = a pseudouridine in tRNA</text>
            <dbReference type="Rhea" id="RHEA:54572"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13934"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>uridine in 5S rRNA = pseudouridine in 5S rRNA</text>
            <dbReference type="Rhea" id="RHEA:47036"/>
            <dbReference type="Rhea" id="RHEA-COMP:11730"/>
            <dbReference type="Rhea" id="RHEA-COMP:11731"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y354"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050188">
        <property type="entry name" value="RluA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600">
        <property type="entry name" value="MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600:SF83">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE RPUSD4, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="9">
        <location>
            <begin position="239"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00041563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1738157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="552" mass="62626" checksum="6507D923E7DFE6B6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3C8</accession>
    <name>A0AAD8Y3C8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyltransferase family protein</fullName>
            <ecNumber evidence="5">2.4.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_010946</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.-.-" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3C8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050194">
        <property type="entry name" value="Glycosyltransferase_grp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45947">
        <property type="entry name" value="SULFOQUINOVOSYL TRANSFERASE SQD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45947:SF3">
        <property type="entry name" value="SULFOQUINOVOSYL TRANSFERASE SQD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="180"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="440"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="4">
        <location>
            <begin position="259"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1738277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="517" mass="57815" checksum="83A1E2688527B938" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y488</accession>
    <name>A0AAD8Y488_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Smr domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009929</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y488"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002625">
        <property type="entry name" value="Smr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036063">
        <property type="entry name" value="Smr_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01713">
        <property type="entry name" value="Smr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160443">
        <property type="entry name" value="SMR domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Smr" evidence="2">
        <location>
            <begin position="463"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="316"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="538" mass="59889" checksum="62C6DCF7B6A3C4C3" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y518</accession>
    <name>A0AAD8Y518_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Glutathione reductase</fullName>
            <ecNumber evidence="12">1.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">QTG54_009366</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the reduction of glutathione disulfide (GSSG) to reduced glutathione (GSH). Constitutes the major mechanism to maintain a high GSH:GSSG ratio in the cytosol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2 glutathione + NADP(+) = glutathione disulfide + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11740"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58297"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="9">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.7" evidence="12"/>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y518"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.30:FF:000003">
        <property type="entry name" value="Glutathione reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000235">
        <property type="entry name" value="Glutathione reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006322">
        <property type="entry name" value="Glutathione_Rdtase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046952">
        <property type="entry name" value="GSHR/TRXR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01421">
        <property type="entry name" value="gluta_reduc_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004776">
        <property type="entry name" value="PRK06116.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737">
        <property type="entry name" value="GLUTATHIONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737:SF2">
        <property type="entry name" value="GLUTATHIONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="FAD/NAD-linked reductases, dimerisation (C-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 9 11" id="KW-0274">FAD</keyword>
    <keyword evidence="3 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="12" id="KW-0521">NADP</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 11 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 11" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042165072" description="Glutathione reductase" evidence="13">
        <location>
            <begin position="29"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="15">
        <location>
            <begin position="83"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridine nucleotide-disulphide oxidoreductase dimerisation" evidence="14">
        <location>
            <begin position="439"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="542"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="268"/>
            <end position="275"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="359"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="400"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="10">
        <location>
            <begin position="120"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1739607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="579" mass="62370" checksum="551109DDEA422F6C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y591</accession>
    <name>A0AAD8Y591_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">M14 family carboxypeptidase</fullName>
            <ecNumber evidence="6">3.4.17.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_009852</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the peptidase M14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.17.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y591"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705:SF119">
        <property type="entry name" value="OS02G0119300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705">
        <property type="entry name" value="PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042072731" evidence="4">
        <location>
            <begin position="24"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M14" evidence="5">
        <location>
            <begin position="42"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1739309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="508" mass="56757" checksum="10802FBF88B484E3" modified="2024-05-29" version="1">MNYHLFKTALIAAVLNGSSTVDASTSTRSLQNTYETINGRSCFRSLDGMIESMTDLVAKYPDLIAMESIGKSYIKKNNPSRSKYDMNYDLPPGYDIYAFNVTNANSARQSSEKGKMLITSGVHAREWAPPELNARFIETLVEGYNTDADITWIMDHNEVHAILYVNPDGRFISEKYPSSYWRKNLNPEGCGNGVDLNRNLDFKWGDRNGASSDPCANDYHGTSANSEPETRAVVEYAKKLFPEDQRKDDPEGQMSAAFGEDITGVYIDIHASGGYVYYPWGHRDAKSPDNEALEALGRKISYFNSYKLWAGGQPDFMYEAAGDYSDYMYGALGVASFGYEIGDDFQQDCARFEDEVVPINLPSLIYAAKLAQKPYKDVKGPDIMEINARVFGGRVRVRAKASDSKMVNSITGFSNHPTGNQIITNVYIYLDVHPDDYQVGDKKYNMEVLDDNWDTSEETVRYDVPTRGLSPGRHTIYVQAIDSRGYKGPVSSKFIDIPAQNSSLRGGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5G7</accession>
    <name>A0AAD8Y5G7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Fucoxanthin-chlorophyll a-c binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">QTG54_009732</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated. Energy is transferred from the carotenoid and chlorophyll C (or B) to chlorophyll A and the photosynthetic reaction centers where it is used to synthesize ATP and reducing power.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast thylakoid membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fucoxanthin chlorophyll protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5G7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030076">
        <property type="term" value="C:light-harvesting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3460.10:FF:000011">
        <property type="entry name" value="Fucoxanthin chlorophyll a/c protein 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 15" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="5" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="10" id="KW-0157">Chromophore</keyword>
    <keyword evidence="13" id="KW-0437">Light-harvesting polypeptide</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="14" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041913659" evidence="16">
        <location>
            <begin position="16"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1739973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="197" mass="21446" checksum="D610FD3F50274372" modified="2024-05-29" version="1">MKSAIIAALIGSAAAFAPAQNKAATTALNAFEDELGVQPPLGFFDPFGLLSGDVSQERFDRLRYVEIKHGRIAQLAFLGQVVTRAGIHLPGNIDYAGNAFDSFPNGGQGQIIAFIGWLEIAFMRDVPGTGNEHVGDFRNGYIDFGWDDFDEETKLQKRAIELNNGRAAMFGILGLMVHEEIQPLGYDPDLPIIGHLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5P1</accession>
    <name>A0AAD8Y5P1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carboxymuconolactone decarboxylase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009759</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5P1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxymuconolactone decarboxylase-like" evidence="2">
        <location>
            <begin position="39"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="219" mass="23857" checksum="A9F1C7B4B179C5A6" modified="2024-05-29" version="1">MSLTELRTSKLWTWKTLLRDHTRFLSMLPNYLAAYVIPGYSLTPTTIESVMVTMNTINTCPYCTGLHGQLARMAGVDKPNPSDAEVVYATAFAHESGRGSDVSSSYDTLVSKIGGKKAQSVRALCWALLWGKTTGNTVNNARDKLVKFQWMQLRTVDLFVVGYYGPLFLVIGVLNKILEVAPSIPKVVSAVVGAVLWLPQALNIIPLGVASIVLNLGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5S6</accession>
    <name>A0AAD8Y5S6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RING finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009389</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5S6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="AntiFam" id="ANF00149">
        <property type="entry name" value="Shadow ORF (opposite cshA)"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1739630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="713" mass="79361" checksum="7DE0DA48D5D036C3" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6U3</accession>
    <name>A0AAD8Y6U3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidyl-prolyl cis-trans isomerase, cyclophilin type</fullName>
            <ecNumber evidence="2">5.2.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008803</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6U3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="1">
        <location>
            <begin position="105"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="315" mass="33551" checksum="A75CFC07094ACD20" modified="2024-05-29" version="1">MCYHLCCPSNRFTSFDRSFIFSFSDGCDKAQKQSSQLEDYIASSYNTTMKQSCAAILSACALFTGASAFAPAAPSVVSQTQLQMGFLDNLFGGGATSADITETVYFDVTSGGEPLGRIEMGLYGDVVPKTVANFKALCTGEKGYGYKGSVFHRGTGGKSIYGRTFPDENFDIKHGGAGTLSMANAGPNTNGSQFFVCTADTPWLDGKHTVFGKVTKGLDIVRKMESLGSQSGATRTETQLSYNIISKAASVASDSTFPSSTFSVTIISLFSLANFCMLSDVIDGIYALRQANAISTSLSSSQRHKAWLFKDIASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y704</accession>
    <name>A0AAD8Y704_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008782</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y704"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="259" mass="27874" checksum="9ECCF5FB83C4E5BA" modified="2024-05-29" version="1">MNPSIFSSSKAAAVPASASSASLSEASASSDMHSASDAIFAADELDGVFRIGSANDSTQSQLGGHLARDSSIRRRRFISPSFATDGELSTFSEEDNDDSDDIQENINSRGIHLSFRQSNRRNIFYPSRRQQSPFSDIFRMPISGAKRQCEDMMAEDDDENQVNTSATPLLSRANCICSSNDSSDDSSTSSSSEESLDHVMSSPSSKRMCLSKGDSPSSYISLFSVTSPATIDYRGADSAIITPRKLEHPLAGGRPLIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y721</accession>
    <name>A0AAD8Y721_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009159</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y721"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="169" mass="18497" checksum="73293628497E04B5" modified="2024-05-29" version="1">MRKHKNHRRFEDKDPSALETTFNQSDCEEDIEEYNYDENANFYPASHVEIKYNDCDKKKSSRFGLGSTFGSASGGKGGGKNNGGKGGKKHAVSKNGKPLSCQDGNGMNAAPIDDVVDDLALEFLAGSGNSKKSKEMKSVRDFRPKLLSGVAPFKAFQGEETEDDDSNEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2024-10-02" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8Z1</accession>
    <name>A0AAD8Y8Z1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF285 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008409</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005046">
        <property type="entry name" value="DUF285"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011889">
        <property type="entry name" value="Liste_lipo_26"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02167">
        <property type="entry name" value="Liste_lipo_26"/>
        <property type="match status" value="50"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03382">
        <property type="entry name" value="DUF285"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1741157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1847" mass="205184" checksum="40F506178EC660F2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9M1</accession>
    <name>A0AAD8Y9M1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008242</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9M1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="173" mass="19908" checksum="B990B866B279CE4D" modified="2024-05-29" version="1">MHIVLSRYIFVSKESDKEGIQCGVDEGFNATNFNTLRFRHRLAVAQTGKCIVDASRSPSNLIKGPHRLYGKECTGGNAHVHNAAMSFRVHHYVGSWESFRLRGEKLFKERNNLHPSTVVDNTTPQYSSPENLTWLSQFVKLVGKENALDLTQRIHLHEVWELEKNFLKLKFKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAB6</accession>
    <name>A0AAD8YAB6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Trafficking protein particle complex subunit 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14374">
        <property type="entry name" value="FOIE GRAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14374:SF0">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1145"/>
            <end position="1208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1588" mass="173313" checksum="DD8C4C0E8B21AA69" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBJ6</accession>
    <name>A0AAD8YBJ6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6824 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBJ6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049227">
        <property type="entry name" value="DUF6824"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20710">
        <property type="entry name" value="DUF6824"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6824" evidence="2">
        <location>
            <begin position="27"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="137" mass="15236" checksum="2A7FF01D29174AA5" modified="2024-05-29" version="1">MVLSPSTSVSSDDEMEGRVVSYLNDYDVLNGRGNDINNLAGNISFQRLIAGNKDRYKECKESEKKNISKDIVDAVRGNGGRFLKYDKSNKIYVDIGNKEARAKTSQAFRDALRKEKKESVKPVGNHSGFSFQINPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCD6</accession>
    <name>A0AAD8YCD6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Kazal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_006557</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCD6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005518">
        <property type="term" value="F:collagen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050840">
        <property type="term" value="F:extracellular matrix binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09631">
        <property type="entry name" value="DOMON_DOH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00104">
        <property type="entry name" value="KAZAL_FS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045266">
        <property type="entry name" value="DOH_DOMON"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002350">
        <property type="entry name" value="Kazal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036058">
        <property type="entry name" value="Kazal_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011142">
        <property type="entry name" value="Spider_toxin_CSTX_Knottin_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13866:SF29">
        <property type="entry name" value="FOLLISTATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13866">
        <property type="entry name" value="SPARC OSTEONECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07648">
        <property type="entry name" value="Kazal_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00280">
        <property type="entry name" value="KAZAL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100895">
        <property type="entry name" value="Kazal-type serine protease inhibitors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50836">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51465">
        <property type="entry name" value="KAZAL_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS60029">
        <property type="entry name" value="SPIDER_CSTX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042261422" description="Kazal-like domain-containing protein" evidence="5">
        <location>
            <begin position="22"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="domain" description="DOMON" evidence="6">
        <location>
            <begin position="76"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="7">
        <location>
            <begin position="256"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="7">
        <location>
            <begin position="359"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="519"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="532"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="588"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="607"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="653"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1742960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="653" mass="69281" checksum="BF469D745703DD02" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCH3</accession>
    <name>A0AAD8YCH3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Trypsin-like serine protease</fullName>
            <ecNumber evidence="7">3.4.21.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_006641</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1743044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000002">
        <property type="entry name" value="Transmembrane protease serine"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000068">
        <property type="entry name" value="transmembrane protease serine 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF91">
        <property type="entry name" value="AT26814P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="Peptidase S1" evidence="6">
        <location>
            <begin position="37"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="6">
        <location>
            <begin position="291"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="6">
        <location>
            <begin position="563"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="6">
        <location>
            <begin position="817"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="6">
        <location>
            <begin position="1085"/>
            <end position="1335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1059"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1743044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1335" mass="145348" checksum="FE2ACCFE800027C0" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCR6</accession>
    <name>A0AAD8YCR6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAM136A family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006039</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAM136 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCR6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008560">
        <property type="entry name" value="DUF842_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21096">
        <property type="entry name" value="PROTEIN FAM136A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21096:SF0">
        <property type="entry name" value="PROTEIN FAM136A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05811">
        <property type="entry name" value="DUF842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="158"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="168" mass="18769" checksum="516F30919A4CAEBF" modified="2024-05-29" version="1">MADLQSKVTQLTSQIEGQLTTMVDEIEKQKLRPMGRNMHSCIVSCYDKIGKSGRKEQIEQCAQNCQMPYQQAGQVTQQEIGNFQNRLQNGMMQCQNDAQAMVTPDMQGDEKKMRQVENNLFKCIEGAVGKSKAELGPMRQRIESRMVLESSNGAGGDSGEKKGWFGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD01</accession>
    <name>A0AAD8YD01_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">40S ribosomal protein S24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_005818</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD01"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00545">
        <property type="entry name" value="Ribosomal_eS24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053709">
        <property type="entry name" value="eRP_eS24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001976">
        <property type="entry name" value="Ribosomal_eS24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10496">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01282">
        <property type="entry name" value="Ribosomal_S24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="133"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="155"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1743197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="166" mass="18501" checksum="A78752172186F338" modified="2024-05-29" version="1" fragment="single">YVQHNISSTHPLHFSPSQSRSSSRLLIPAIMSDSVVVKTRKFMKNPLLSRRQMIVDIIHPGRANVPKSELQEVVGGMHKADGKLVVLFGFRTKFGGGKSTGFCVIYDNEDALKKFEPKHRLVRLGLETRTEKSRKAIKEAKNKGKKIRGTGASIAKHKAKRAAQND</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDC9</accession>
    <name>A0AAD8YDC9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004944</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDC9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAP" evidence="1">
        <location>
            <begin position="81"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="132" mass="14822" checksum="26FB52112CFF39EB" modified="2024-05-29" version="1">MESESESESESKRALYDTPKSMVPTPRRCARGWTIDDSGVLWCGVGLGFGWRWASDALISTSSLEDSNESDEGHVMNREELQLLTVAQLRIKLKAVGLKVSGKKDVLIDRLLNPNLHRKNHKIGGRARQKLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDH1</accession>
    <name>A0AAD8YDH1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Indole-3-glycerol-phosphate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004766</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDH1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042159718" description="Indole-3-glycerol-phosphate synthase" evidence="1">
        <location>
            <begin position="33"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="324" mass="34515" checksum="8E30A4A0BDF57B8E" modified="2024-05-29" version="1">MMMASTNATTLRWVGFILALIGAMTSTSSCLAFVPQPVPSTHCVALSMSSTLFQPTQTSLDKLDNLKLSIKKPRGASISVEYSRLNNELSDGDLKILSMQLRRSAKAAAIWSSDVESIAKLVKEQESARGDFPGPLPVIYSGSLSDADVVKTVVDGGVTAVVADYGASLDEAVTSLLSEVGIIWKVSSLDEMKEVQQSENMGNVILLSKEVLPASIDDDASDDELAESLSNKSVVTIAQIQSMMPANAEIQLGKDLAKLGVSSLVLEQACVGDEEDVKYTSYAIEELNKKSSSSFSMTGLTGSTNGHFGVSSHGGEVKWRRHAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDM8</accession>
    <name>A0AAD8YDM8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_006163</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CSC1 (TC 1.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDM8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032880">
        <property type="entry name" value="CSC1/OSCA1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF5">
        <property type="entry name" value="RE44586P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13967">
        <property type="entry name" value="RSN1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="440"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="505"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="536"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="623"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="672"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="701"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like N-terminal transmembrane" evidence="10">
        <location>
            <begin position="43"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="11">
        <location>
            <begin position="188"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="9">
        <location>
            <begin position="487"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="299"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="767"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="321"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="769"/>
            <end position="779"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1743542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="818" mass="90878" checksum="B639EC9449B4EA9A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDU6</accession>
    <name>A0AAD8YDU6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sel1-like repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_005555</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDU6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="15"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="80"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1743958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="301" mass="34443" checksum="ADEF00186D94EA4B" modified="2024-05-29" version="1">MATADLEAEVAEMSCASCGIAEIDDIKLMECNVCDLVRYCSVKCQRDHIPQHLQVCKKRAFELRDEILFKQPESSHLGDCPICCLPLSIYKKNFTLYSCCSKRLCNGCMYANKLRQIEGRLEETCPFCRQLMPDTDEEVKMNLMRRIEANDPIAMHEIGMMRYLEGDYEAAFDYWTKSAELGDVVAQYNLTTLYFEGEGVEKDEKKELYHLEEAAIGGHPVARYNLGCYEEEHERIERAVKHYIIAANLGHDKSIQALKECYADGTISKEDFAAALRGHQTAVDETKSQQREEATIFFVKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YF26</accession>
    <name>A0AAD8YF26_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004632</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YF26"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="12"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="152" mass="17356" checksum="B175FC6ECAB54FED" modified="2024-05-29" version="1">MTSHAETKIDCSKVYVKQSSFSNEETGMFDGAFAAVDIKEGELVEKGLMRRLPEGFDGNTCPYIFTWSTERPNKTWGMGSGCAPYYNTCKEGTANTKMVRFFDEDRFEIYANCDIKKDEELLHTYISLKWRTCFSELNDIVHADDSEHKADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFF4</accession>
    <name>A0AAD8YFF4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_004759</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFF4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47776">
        <property type="entry name" value="F5A8.9 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47776:SF2">
        <property type="entry name" value="RING-TYPE E3 UBIQUITIN TRANSFERASE BRCA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="269"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="68"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="141"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="83"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="162"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1744226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="327" mass="36816" checksum="7014AD5AAB1D8D66" modified="2024-05-29" version="1">MNLHMQLANGRLFKAPAPAAGRDRRRMAMTDVTNVLIAGMSHPPNIVRTMNASDDFEDIIHAPTTKFQYQDCSPPWPHHDVEQQQQQPSSQRRASHRRLHAMDYYDIVSTTQAYPSHGVADGVSRPTPTRKFEQLRNNTLCNQRTSRSSDFHSSHAALHTQKYPSVSSSSKQLYSRHHHHCSQNSQDTVKPSFIVPSNISELISDLNAKAKLLSREEEEEYDDSSSLDYSSDDSMIEAAIYKSVAPPPPSIKQHQEQSMGGTSMKDLICAVCLDFPDDPKHIASVSGCTHRFCFSCIDSWAKRGNNECPLCKSTFHLVASGDRVRWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGJ8</accession>
    <name>A0AAD8YGJ8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Threonylcarbamoyl-AMP synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_003457</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGJ8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.870.10">
        <property type="entry name" value="DHBP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="Sua5-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="YrdC/RibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042259430" description="Threonylcarbamoyl-AMP synthase" evidence="3">
        <location>
            <begin position="18"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="YrdC-like" evidence="5">
        <location>
            <begin position="64"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="271"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="312"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00015492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1745533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="354" mass="38877" checksum="4565F6858B4548E9" modified="2024-05-29" version="1">MILRHALLVFIASQAYTDTATTTSVYAFSSVNSSKSTTPAYAPSASSNTNEDSLARVKQWSASSPMVDEAFDVLCKGGTVLCPTIVGYSLFALDGKEGAAKLDKVKGRENKPYGVVGSEATFSRLFSGRTAPLMKNDFCSDMFLSFVSSDSVSNEARDQLRISRAVGPSDEVAMWINSGPVFDTIIEKVEAKYEGTRYILVSSGNLSGNGNPKSSTFSIDAIDDEILARVDMVVDTPHWSDPELDENGRWYSAPMFDMDSCAFRRVGKNMETASVVLSLFHEIDVDNSQVIDLEEFKVFFGSGRIGKELANLHEEEVETMFQLIDEDGSGEIDFEEMYSFLSSNKSVSFNVKFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGM7</accession>
    <name>A0AAD8YGM7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membralin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004016</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGM7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904294">
        <property type="term" value="P:positive regulation of ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21650:SF4">
        <property type="entry name" value="MEMBRALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21650">
        <property type="entry name" value="MEMBRALIN/KINETOCHORE PROTEIN NUF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="410"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="771"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="862"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="887"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="919"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="942"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="274"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1031" mass="115127" checksum="B8802DE42B1B5D41" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YH53</accession>
    <name>A0AAD8YH53_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_003353</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YH53"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="224"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1745429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="287" mass="32413" checksum="9711741270642977" modified="2024-05-29" version="1">MPSRKKAQGKARKAAKADKAKEAASVPPKDFTEVTLDSWLTCDDGESEKCKHGCDLSLPKSEHDCRDFAMRYANDFLIELCRMFGNDQLLKNASTSNDLVGQCVQQGKPFVAAIDDMEEKYPEVFESPSKLKWAISFYHSKGTQDVIDGNMKRAHHAAICATLMNGYLSNSSDVSPMKIWDIVQADNKTILTYFRKRTSCSCLDEKRKEYKGVKKTGKCCNDQCPLPERVAERSSLLYCTACKLVQYCSAECQKAHWKYHKHRCTNIAKLNSVDDELQKIAQVNLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YH97</accession>
    <name>A0AAD8YH97_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_004376</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YH97"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12347">
        <property type="entry name" value="RRM_PPIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034168">
        <property type="entry name" value="PPIE_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48037">
        <property type="entry name" value="ATPASE E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48037:SF1">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="13"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="116"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1745085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="150" mass="16514" checksum="CB4316D882153862" modified="2024-05-29" version="1">MSSSQTPTLQSRRALYVGGLDPAVTQSMQTVETTIRAAFLPFGPIQSIEIPMDYAAGTHKGFAFIEYVDGDDAAEAIYNMDGAELFGKTLTVNIAQAERMNLGSNKAVWSTEEWFKEQSGMKEDEERKEQEKGKELDASLLKEKPLTAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHB8</accession>
    <name>A0AAD8YHB8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_004406</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHB8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008048">
        <property type="entry name" value="MCM5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054125">
        <property type="entry name" value="MCM5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF42">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21933">
        <property type="entry name" value="MCM5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01661">
        <property type="entry name" value="MCMPROTEIN5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="9">
        <location>
            <begin position="787"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="380"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="445"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="461"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1745115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1262" mass="137375" checksum="7E384230DDBC8FAA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHM6</accession>
    <name>A0AAD8YHM6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer spore wall protein LDS1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHM6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052786">
        <property type="entry name" value="Spore_wall_assembly"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34292">
        <property type="entry name" value="OUTER SPORE WALL PROTEIN LDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34292:SF2">
        <property type="entry name" value="OUTER SPORE WALL PROTEIN LDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="329" mass="36513" checksum="FA9E83D8612A15DA" modified="2024-05-29" version="1">MNSLISKGTPSLHKAVMKHRYGKDPIFYPLQALSYALSHRELFWTVLKVACVGITVSIIILVILLVTALQPQAQAISPNLEWWAWLIAVFLVLFEAGLISVLLMSVSQSKAQTKVFTATMKIEGVWREDMIEQSMAKDLNPMKKAFIVRILTLPLQIIPFIGGAMYSAINATFIGWDHMDRYFDAIQLSPKLQRVEIFGHELSDCRALCNPATYDLDNDIARFGFFCGIVESAPIIGFVLGPVTNAIAAALFACDIEHSGGLLCLREEAQDEEANQESRGPLDALREKGEKALQFGESIANNENSDSQASRYLKKKARESIVSTLSKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YI68</accession>
    <name>A0AAD8YI68_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002082</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YI68"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="68" mass="7074" checksum="6047167987B81E4D" modified="2024-05-29" version="1">MERVLGVKLPRPGKKPAAKLSAAEGAKKGGVVRGGPPKRSVQGSRTELSSFGGTISSYSNVMNEQLYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJE1</accession>
    <name>A0AAD8YJE1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA-(apurinic or apyrimidinic site) lyase</fullName>
            <ecNumber evidence="3">4.2.99.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_001647</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the type-1 OGG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034039">
        <property type="term" value="F:8-oxo-7,8-dihydroguanine DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006285">
        <property type="term" value="P:base-excision repair, AP site formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1670.10:FF:000005">
        <property type="entry name" value="N-glycosylase/DNA lyase OGG1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="entry name" value="Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="entry name" value="Uracil-DNA glycosylase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012904">
        <property type="entry name" value="OGG_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052054">
        <property type="entry name" value="Oxidative_DNA_repair_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10242">
        <property type="entry name" value="8-OXOGUANINE DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10242:SF2">
        <property type="entry name" value="N-GLYCOSYLASE_DNA LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07934">
        <property type="entry name" value="OGG_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55945">
        <property type="entry name" value="TATA-box binding protein-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="Uracil-DNA glycosylase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10 15" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="14">
        <location>
            <begin position="508"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="domain" description="Helix-hairpin-helix DNA-binding motif class 1" evidence="13">
        <location>
            <begin position="609"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="domain" description="HhH-GPD" evidence="14">
        <location>
            <begin position="1238"/>
            <end position="1423"/>
        </location>
    </feature>
    <feature type="domain" description="Helix-hairpin-helix DNA-binding motif class 1" evidence="13">
        <location>
            <begin position="1339"/>
            <end position="1358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="328"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="713"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1048"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1441"/>
            <end position="1462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="328"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="339"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="713"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1048"/>
            <end position="1065"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1747684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1462" mass="164505" checksum="A64A2F37258C7D84" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YK37</accession>
    <name>A0AAD8YK37_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3754 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_001535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YK37"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022227">
        <property type="entry name" value="DUF3754"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33645">
        <property type="entry name" value="AMINOPEPTIDASE (DUF3754)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33645:SF2">
        <property type="entry name" value="FAMILY PROTEIN, PUTATIVE (DUF3754)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12576">
        <property type="entry name" value="DUF3754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="703" mass="79243" checksum="F2DFC4C695F1A51A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKE3</accession>
    <name>A0AAD8YKE3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="7">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_000160</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKE3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02674">
        <property type="entry name" value="Peptidase_C19R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF24">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="91"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1748221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="485" mass="55591" checksum="705770C3D72F5AF1" modified="2024-05-29" version="1">MGKCQSIDVSRREPMGENSLQEPMVGNKKRNRHLESMARVGSRVFMPESRASPTKSNTNTTLKEHKASTYDHVHELVNDGININDNGSGKVGLMNLGNTCFMNSSLQCLSNTEPMTDYFLGYDYRSEINADNIFGTKGALVRCYAELTKHLWLGKSKSYCPEEFKSSIGRFAPQFEGYEQQDAQELLAYLLDGIHEDLNRVLIKPYIEDKDCDGSNDEGDAIIAWSNYLSRNKSIIVDLFQGQLRNTMTCRNNKLIQADGTHGCGHKNVKFDPFMYLSLPISDTSNTLDDCLSLFCEEETLKGDNQWYCTKCKTHVDATKKIDLWMLPPILIIHLKRFKFGVTGHRSKIERPICYPLSDWNLSTRKKSEGGVFPLYDLYAISHHRGTVSGGHYTAHAKNRFDREWYDFNDSQCRKVDKEKEKLGFGSSAYCLFYNRVERNHNAAQERTTTIRRQSISRPELWPHLQRDAVKQWASTRVDLDYTVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKI9</accession>
    <name>A0AAD8YKI9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter, ABC-F family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_002369</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKI9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000104">
        <property type="entry name" value="ATP-binding cassette sub-family F member 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF134">
        <property type="entry name" value="ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="214"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="565"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1747025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="801" mass="89039" checksum="0501A475691136F2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YL83</accession>
    <name>A0AAD8YL83_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_000613</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YL83"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1748674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="146" mass="16354" checksum="EEF17C62D22E5C05" modified="2024-05-29" version="1">MSMKSLYGIYGIELWRTVEGLLLKRVTQDADEINRKYWNVDKPQESFKKLTDKSNKGYLAPEPVGPGCGLPGALWSEIGKYATNGLNGIGHSNVSHDVHWREVDELADDPDQPYDDRLQHLAKAGFTRAAGSIQCEEFSWNGNLLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLE9</accession>
    <name>A0AAD8YLE9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA (cytosine-5-)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_001405</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLE9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044027">
        <property type="term" value="P:negative regulation of gene expression via chromosomal CpG island methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050390">
        <property type="entry name" value="C5-Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10629">
        <property type="entry name" value="CYTOSINE-SPECIFIC METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10629:SF52">
        <property type="entry name" value="DNA (CYTOSINE-5)-METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="108"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="108"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1747442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="653" mass="72633" checksum="FBF52AE97D61C065" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLI9</accession>
    <name>A0AAD8YLI9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000537</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLI9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="444"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="566" mass="63766" checksum="857E1B175B50C91C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YME8</accession>
    <name>A0AAD8YME8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Spindle pole body component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_000113</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
            <location evidence="5">Cytoskeleton</location>
            <location evidence="5">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TUBGCP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YME8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051011">
        <property type="term" value="F:microtubule minus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF13">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="7">
        <location>
            <begin position="110"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="6">
        <location>
            <begin position="458"/>
            <end position="839"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1748174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="847" mass="97980" checksum="2D2DFE8E58D98A31" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMJ2</accession>
    <name>A0AAD8YMJ2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000682</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMJ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34370">
        <property type="entry name" value="OS04G0600100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34370:SF1">
        <property type="entry name" value="OS04G0600100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042060098" evidence="2">
        <location>
            <begin position="25"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="262" mass="28849" checksum="AB261814F58D15FE" modified="2024-05-29" version="1">MMERFSRLFMAFLALSFTFMRASSFGTSLSPLPTTTRVKQHPHLQLIHCSNGDAYDRSKRQGGWRCYSTNEPSDNQEDTEQNIQTAEVTADSLTPSQIQSLSPDSQTSSFFGTLKSFFSNKKNKFSRESLGKLGMSALLAYGFVSNISGVIAVSCAWFIFCTRTGLSPLAPGQKTAFLGIYAGFTVMLNVIRPARFALSISISPYFERIRKFLQRKFNVSPRGAAVLMILFINLLGTCSLMCLGVWIASLLAGVPVWGGGII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YNC5</accession>
    <name>A0AAD8YNC5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Subtilisin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000563</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YNC5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042200239" description="Subtilisin" evidence="2">
        <location>
            <begin position="18"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="324" mass="35197" checksum="FDB682E6504111A9" modified="2024-05-29" version="1">MKLHLLLLLLFYRNASAQQSAAGQDTVIGIVGRDFVMMGADTSSSGGGGISLTSSNIDKLAVIHDGGGDDALNNMLHTDNDISSSDCFSNKRSVEQQAIVVGFAGDAADADVMAGTLKIHTQVREYEAGIGNDIVCTFDGESSSATISNVALGSISPAGLDAESIAYFARKEIATRMRSRQPLQLCLLVGGMKQVSAASSAYRLSSKSNTDDEKQNHKPTMTQERVISRQESPTIFSVTQTILAGSIRIIAELIIWLSWLWIKLCLVGTRSKISKGNVTPRSEELIMECFEQLRQRYLINSPQPPRIKCIDAFGVRELESKYKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPD8</accession>
    <name>A0AAD8YPD8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mitochondrial import inner membrane translocase subunit Tim21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_000896</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the TIM23 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion inner membrane</location>
            <topology evidence="8">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TIM21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPD8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.320">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit Tim21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013261">
        <property type="entry name" value="Tim21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038552">
        <property type="entry name" value="Tim21_IMS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13032">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13032:SF6">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08294">
        <property type="entry name" value="TIM21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1748957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="272" mass="29998" checksum="0DD31345D1714208" modified="2024-05-29" version="1">MSLRPIIISLTTGRTSLSSLRLGSLPSKTMQSRSLGSFAVTAQYRFGTLTKANITKYCQRPNLAVRSMASSSSSSGEKKASEKANVDSEEATSSEIVLTPGEKVVVGSRLFFWSGVFAFASVCAYYIGKELIPTKMSPNTVFDKATDIIRQNREVQQRFGEAFKTYGRDHGGHREGRRNFIEHTEYVNQDDGTKRTRVRFNLEGPYGQAFVFAEVSKDMPSGEYVYILVQDKRNGAVITVQDNRSSLLAKKLAGGDKDGQDVFSQLLSGGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPJ7</accession>
    <name>A0AAD8YPJ7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Thioredoxin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_000770</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPJ7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016671">
        <property type="term" value="F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044241">
        <property type="entry name" value="TxlA/HCF164"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47353">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN HCF164, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47353:SF1">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN HCF164, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="54"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1748831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="225" mass="24850" checksum="AE38CA1E6CF628CE" modified="2024-05-29" version="1">MDTAQQGEGILTSQNLSTHNSDSSTEMEIIKKNKLRNVIIAVSSFAFAIANFVWQLTHPVTAVSILVSMENKSAPLTSIGNNGKPTVIDFWAPWCSNCKVAAPTLQAVEEQYGDSVNFIMVNGDDGKNWPLIQLFGVDAIPHLALLSDEGDVETALIGPMSRNVLRADIDALLTKRENCEAAPVCHEELPYKMYDAFSNRESRNINFQRAMDEIERSRAMSSSQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4N0</accession>
    <name>A0AAD9D4N0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Diatom pyrenoid component 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015413</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4N0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057486">
        <property type="entry name" value="DPC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36494">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36494:SF2">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25195">
        <property type="entry name" value="DPC2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041995341" description="Diatom pyrenoid component 2 domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="domain" description="Diatom pyrenoid component 2" evidence="2">
        <location>
            <begin position="66"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Diatom pyrenoid component 2" evidence="2">
        <location>
            <begin position="200"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="Diatom pyrenoid component 2" evidence="2">
        <location>
            <begin position="363"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="Diatom pyrenoid component 2" evidence="2">
        <location>
            <begin position="509"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="domain" description="Diatom pyrenoid component 2" evidence="2">
        <location>
            <begin position="671"/>
            <end position="767"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="783" mass="75888" checksum="6B1A79740E7FA92A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4X5</accession>
    <name>A0AAD9D4X5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ankyrin repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015204</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4X5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="495" mass="55184" checksum="DCA9232ADF51707B" modified="2024-05-29" version="1">MTEREYSSQSAELLLAHELTAFCHSDSLSEEGLHEIIVHHNYLTPNNNESEYTFFLAACRNERVTTGIIQCLLEYFPDAAAAETPELFVPLHIACSNINVTPGIVQLLIDAHPDSVRRANNIGWTPLHHLCVNQNLGDADVFSILKLLVERYPDLVRRADNAGNLPIHVASIGGSPEFCSVLIEAYPGSERMSNDSGRLPLHRACRNNAIATVEYLYKLYPDAINHAATNGLYPIHYSIFDCALRGSFDAVEILKFLLDCDPSVKLQKLVGKSLLHVACQQDYNDSNIDAGILVINAVYDAHPKAIEYSSFAAKVPRFHERIQAIINSLLVYSRQAKDRRMMSTPDDNGQLTLHFALQIDSPLGSIKLMVKGYRAALQYPDNSGALPLHIACEYHESPRVVQYLVGLDATTLDAVDREGNTALHYACRGAKFDTITLMLETFDAVSVSIRNAHGKLPIDLLWERNEVLDRESIEYMESVFQLLKAYPETLMSTGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D584</accession>
    <name>A0AAD9D584_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heme-degrading monooxygenase</fullName>
            <ecNumber evidence="3">1.14.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015059</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.-.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000040">
        <property type="protein sequence ID" value="KAK1734292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050404">
        <property type="entry name" value="Heme-degrading_MO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34474">
        <property type="entry name" value="SIGNAL TRANSDUCTION PROTEIN TRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34474:SF2">
        <property type="entry name" value="SIGNAL TRANSDUCTION PROTEIN TRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51725">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="2">
        <location>
            <begin position="2679"/>
            <end position="2785"/>
        </location>
    </feature>
    <feature type="domain" description="ABM" evidence="2">
        <location>
            <begin position="2832"/>
            <end position="2942"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="316"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1228"/>
            <end position="1248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2615"/>
            <end position="2640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2916"/>
            <end position="2937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2616"/>
            <end position="2629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2916"/>
            <end position="2927"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="2928"/>
            <end position="2937"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2955" mass="327717" checksum="44BFBDB8B781D414" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5C5</accession>
    <name>A0AAD9D5C5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015747</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000047">
        <property type="protein sequence ID" value="KAK1733574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5C5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="407"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="407"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="965" mass="102262" checksum="3B2BFFEE9EFF34BB" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5T3</accession>
    <name>A0AAD9D5T3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_014227</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5T3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050930">
        <property type="entry name" value="MFS_Vesicular_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23506">
        <property type="entry name" value="GH10249P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23506:SF26">
        <property type="entry name" value="MFS-TYPE TRANSPORTER SLC18B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="342"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="379"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="410"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="434"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="476"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="508"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1735161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="542" mass="60085" checksum="5E7B5CE44867F3A2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D602</accession>
    <name>A0AAD9D602_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HpcH/HpaI aldolase family protein</fullName>
            <ecNumber evidence="5">4.1.2.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_015178</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HpcH/HpaI aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.-" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D602"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050251">
        <property type="entry name" value="HpcH-HpaI_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30502">
        <property type="entry name" value="2-KETO-3-DEOXY-L-RHAMNONATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30502:SF0">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH/HpaI aldolase/citrate lyase" evidence="4">
        <location>
            <begin position="78"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1734175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="323" mass="34767" checksum="D2E2A4E1DC16070B" modified="2024-05-29" version="1">MTSPLISSSASRLLMRHYRLASVTATKKNYHRCTSNNAQNNNNISLPEQHSLSNGTLRHKLRTGQPTLGVVTGFHNDTDHAETLGLLGYDFLWADAEHSTANASTVANLILAAERRGLPTLVRIGYGYQNVIGHSQKFLVAGAQGIILPQCESADDVHKIVDAVKFPPIGRRGLAGERWNSWGLGGQNNGGGDVTLADCVRTSNDNSIVGVVVESRRGIEALDEILSVEQIDFVFVAPTDLSADMGLHGQIRHPDVVDMVDKAGQTIRAAGVSSGMLALNGDDYVKYRQLGFQVMVGVAHTMFAEGARSLKSRAEDYESSGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6X3</accession>
    <name>A0AAD9D6X3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Actin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_014094</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6X3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000291">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000001">
        <property type="entry name" value="Actin, muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000404">
        <property type="entry name" value="Major actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00406">
        <property type="entry name" value="ACTINS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="358"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="410"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="585"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="360"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="428"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="438"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="513"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="529"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="541"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="589"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="599"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="614"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1735028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="629" mass="69160" checksum="589A75151D6165F9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6Z1</accession>
    <name>A0AAD9D6Z1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014261</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6Z1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="174"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="368"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="204"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="467" mass="51327" checksum="FF54D6FE5C060696" modified="2024-05-29" version="1">MNDKSNKDDAAPATVPNPLLAAPVEKYSSAKAAAVKDNSDRLKRQAEKARATEVTNAAAAAAAMQRRPVHHHHQQQQPPGMFGFNHMMGGMMGGEFPYPGAGMNYFHPGMPTPFVLQPNPASIPPAPAFKSTAAAPSAPQVSTAGSILATAGSSIPLPSPINSVKRKTADDTIVQRLTKKQRPSSTTTQSLLIDLTAQQERKNTGTTKNKSTPAKSTPRDPPGFEAFQRDPSFITSIMASRMKGDGNTDRLLGPLARGIINMSDEKIFKLSNDENDATMKTFVTDVIMPLLGIDDHIAQSNYSNWQGYAHISSENLRSVAKNFFYVRRSSMKAAVQVAFYEMKKNHQKILQTGGYRSNNSDESTAIKVQQLERALEKQKEDNAKMTKQIEEIYESDIADMRNDHKLHVEELKEAHKKEVKALKEEMEDMKSSHREFLGHYVEAAAEAVRFAQKQGEPSCGFLAKNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9Y1</accession>
    <name>A0AAD9D9Y1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010847</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36489:SF2">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36489">
        <property type="entry name" value="PROTEIN-COUPLED RECEPTOR GPR1, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="558"/>
            <end position="1804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="558"/>
            <end position="1712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1719"/>
            <end position="1744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1745"/>
            <end position="1758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1759"/>
            <end position="1783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1793"/>
            <end position="1804"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1804" mass="170999" checksum="D8D0116A42BD81B4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DA97</accession>
    <name>A0AAD9DA97_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Phytoene dehydrogenase-related protein</fullName>
            <ecNumber evidence="8">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_009735</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carotenoid/retinoid oxidoreductase family. CrtISO subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DA97"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052206">
        <property type="entry name" value="Retinol_saturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46091:SF3">
        <property type="entry name" value="AMINE OXIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46091">
        <property type="entry name" value="BLR7054 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1739976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="652" mass="73118" checksum="7FED7FDC9CDF8950" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBF9</accession>
    <name>A0AAD9DBF9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Trypsin-like serine protease</fullName>
            <ecNumber evidence="7">3.4.21.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_008429</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBF9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050127">
        <property type="entry name" value="Serine_Proteases_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24264:SF65">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24264">
        <property type="entry name" value="TRYPSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="Peptidase S1" evidence="6">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1741177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="160" mass="17565" checksum="4BE480560D817C47" modified="2024-05-29" version="1">MLIFLNEPVTSRNHTVEYIKLNSDSTVPNAGDPVTVIGHGVTKENDSVLSSVLMEVEVFALSNEECKKDSYESLTEDMLCAADTNKDSCQGDSGGPLFVKGDKYDLQIGTVSWATGVRMQAVRITACYYENKDAVLTLTLLVVGLLLCRSWSIFADFQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBY0</accession>
    <name>A0AAD9DBY0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Choloylglycine hydrolase</fullName>
            <ecNumber evidence="5">3.5.1.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_009153</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C59 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.24" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBY0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045302">
        <property type="term" value="F:choloylglycine hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.60.10">
        <property type="entry name" value="Penicillin V Acylase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029132">
        <property type="entry name" value="CBAH/NAAA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052193">
        <property type="entry name" value="Peptidase_C59"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35527">
        <property type="entry name" value="CHOLOYLGLYCINE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35527:SF2">
        <property type="entry name" value="HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02275">
        <property type="entry name" value="CBAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Choloylglycine hydrolase/NAAA C-terminal" evidence="4">
        <location>
            <begin position="9"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="303"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="314"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1740203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="339" mass="37252" checksum="0C145D41CA45BC2A" modified="2024-05-29" version="1">MGPGQVCEGMGIDVDTASDGMNEAGLGAHMFYLGEEDGTAYAEPSTTDDMNVNYMRLVRYILDNFATVQETVDALRQVRLTAGNLCFGEGRELGVHVAIEDATGDSAVIEHVGGEMQIYHGKNITVMTNEPAMNKQYELLKQFQPWGGDLVLPKNLPGSVASENRFVRLKYYIDYAPKPKSEAMAIAIIKSLIASTNVPFGAPVSCHRRIAIFLPLLRLSQPLLSLSDSIKAGFTRHGGRALLIAPISEVYYFGWLETPNIIWTDFSKIHKIGAFEERQPNLRLKPQYPKLVGDVVCEFKTEDGKAPAGCAQEAGKEKKRDKSPKTDKVLRGAVNVADK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBZ0</accession>
    <name>A0AAD9DBZ0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBZ0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43941">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18143">
        <property type="entry name" value="HAD_SAK_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="546"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="701"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="91"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="709"/>
            <end position="719"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="749" mass="84972" checksum="9FE4923914680981" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBZ6</accession>
    <name>A0AAD9DBZ6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_007499</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-13 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBZ6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007019">
        <property type="term" value="P:microtubule depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01367">
        <property type="entry name" value="KISc_KIF2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000012">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47971:SF20">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KIF24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47971">
        <property type="entry name" value="KINESIN-RELATED PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 7" id="KW-0493">Microtubule</keyword>
    <keyword evidence="4 6 7" id="KW-0505">Motor protein</keyword>
    <keyword evidence="2 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="9">
        <location>
            <begin position="90"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="328"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="182"/>
            <end position="189"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00061030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1741926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="586" mass="66539" checksum="9685C29C4C8BFCF1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCI5</accession>
    <name>A0AAD9DCI5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_008161</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCI5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0085020">
        <property type="term" value="P:protein K6-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF8">
        <property type="entry name" value="BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="32"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1740909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="186" mass="20238" checksum="A26D61F5C29CACE0" modified="2024-05-29" version="1">MLLFNASKSGDVATVQALRESGVDIIGGRQENGMSSILLACRNGHIGLMDYLLEQGANPNDAENYGGTCLMAAACYRHPDCVRRLIDAGSDVEYAYPGDNASIIYMTAYCFSKDADEGNLDFEEGSVIRTVELLLEAGAPANTTQIDHATGRTKSALQVLQEMIPFDDKVRRERDGLIALLQQNEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DD76</accession>
    <name>A0AAD9DD76_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phospholipase B-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DD76"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042194889" description="Phospholipase B-like" evidence="1">
        <location>
            <begin position="20"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="389" mass="44214" checksum="74F718D87D8F296F" modified="2024-05-29" version="1">MPSTLSTAIIAALATGTLAREDVFPVTKPDFRYQEFSKLNRVQQKAATDQLDYTAVTWNALGLADVERKGWDYLTTDQQIGATQVGFTKESWDCFIDHYSSAYWAELVGNNKASQYMRLGWSQQSWEGEGAHPTTEGKWWDQLSEDEKKAANSLCFFKKNWNSEDMNPNDSYFPFKFPEFRYQPWNELSLSMQNTAIGMMNYTEDLWNDLGTHVAEKNTFLNLDSVTREGAMELGFYTHNWDCFINHYQAYYWSSFHSDLLVAVETLGWSEASWTNDMQSPPLSESKYWADLSPEEKAAATRLCYFEETWDTNEYPTLEDFDISTAVTPDGPLPQDINLNIYETTGYAGRSPGMVAAGQYIYNTNASYRTVVSSTVLGVVALAGAFLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDE8</accession>
    <name>A0AAD9DDE8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005853</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDE8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="440"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="459" mass="53038" checksum="B42E811BB5194CEE" modified="2024-05-29" version="1">MTMENIQADEETRPLAQPQRRVAEAYAESNVGASILKKSSFWILVFVAFLVFSAAEGEDVSAVKKKKREMKLRNKAEIAPAEVVKRQSDINHKIDLHEKYEQLEVSAPGAYGAEKFNDNEAVPSSYDDEDSEGSEEDLDEEIDTVLADVDEAEEEEIEINDSMLVSAVRNIEDNVKLYFGRVFGDTEDASSDFIDDLNESEDETSADIQLSDEQLDLIAKKIADRLEADVKKDFRDKADVIAEEKVEEIDQVINEDRKSDMDANKIKEDVAEAEKVVVEDLRDEIDKAAVKVKQSLPDKVERIRNEVMEEETGRNMDYIERKKRQRREKMMKRAERLYDERLQKRKEFDEANGKRMDGEKSKYNNEGSSGGKYYRASKKVMPITSSDEFESRQQKKPSDYKKKKYSNSNDASEKYYQTKKKKKQMPLSSDDEQPSRQKVYKKEQYVGEEKEYYEDESSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDK1</accession>
    <name>A0AAD9DDK1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">GTR/RAG family Ras-related GTP-binding protein</fullName>
            <ecNumber evidence="9">3.6.5.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_007428</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GTR/RAG GTP-binding protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDK1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990131">
        <property type="term" value="C:Gtr1-Gtr2 GTPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010507">
        <property type="term" value="P:negative regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11385">
        <property type="entry name" value="RagC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006762">
        <property type="entry name" value="Gtr1_RagA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039400">
        <property type="entry name" value="RagC/D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11259:SF2">
        <property type="entry name" value="GH16429P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11259">
        <property type="entry name" value="RAS-RELATED GTP BINDING RAG/GTR YEAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04670">
        <property type="entry name" value="Gtr1_RagA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="35"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="190"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="448"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="482"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="57"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="191"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="215"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1741855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="568" mass="61398" checksum="044D5B1783515461" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFI1</accession>
    <name>A0AAD9DFI1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thylakoid lumenal 17.4 kDa protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005507</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFI1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47485">
        <property type="entry name" value="THYLAKOID LUMENAL 17.4 KDA PROTEIN, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47485:SF1">
        <property type="entry name" value="THYLAKOID LUMENAL 17.4 KDA PROTEIN, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041972160" evidence="2">
        <location>
            <begin position="19"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="214" mass="22893" checksum="D603B70567C21BE5" modified="2024-05-29" version="1">MVAKTTLISLLLASSTSAFAPPQMQTTTSRTTQLSATKNNNNNIEIAAATFAIASSLLLSPLSASADGQTKEFKLPPIDQSDKSRCVLNSSKMGQANAARDKLYDLRECPLSGVKGNEFDLSGVIMTGTDVSKANFRDAQFSKGYLRNSNFDGADFTNAIVDRATFKGSSLKGTIFANAVLTATSFEGADVENADFTDAYIGDFDIRTCVRIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGD8</accession>
    <name>A0AAD9DGD8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_004191</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGD8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052839">
        <property type="entry name" value="Mito_gene_expr_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46920:SF1">
        <property type="entry name" value="PROTEIN MSS51 HOMOLOG, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="9"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1744900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="279" mass="31043" checksum="8914E545BA3D36AB" modified="2024-05-29" version="1">MGLDNIDTCANCGKKEGEGGTNLKRCMACKYTYYCGAECQKANWKKHKKSCEYLQMPTIDRAYAGEEGSEPAVIPGMGGMECSTCARNGVACSCSSEPMSLWRPQGGARTFIGTVMVKTTTGAAMFKKLDDPKDFPVNLPSLPGHYQTIWENMSELNHCDDSEGNFLKEMKARDISKYLVDYRGHKKESGKEDESMYPFHENLVSFSPYTGSPAPKVRADDIIEATVAKDMSVFGFPVKKGTALQVVTGIVQTNRNKMWVYFPIHHAKLLVVRGKNWKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DH10</accession>
    <name>A0AAD9DH10_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sulfotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003693</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DH10"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053259">
        <property type="entry name" value="Golvesin-related_Golgi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32301">
        <property type="entry name" value="COUNTIN RECEPTOR CNR3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32301:SF6">
        <property type="entry name" value="GOLVESIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="394"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="455"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="480"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="863" mass="95612" checksum="4C2EF7EFE629D776" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHF3</accession>
    <name>A0AAD9DHF3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phenazine biosynthesis-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_001889</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhzF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHF3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.10">
        <property type="entry name" value="Diaminopimelate Epimerase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003719">
        <property type="entry name" value="Phenazine_PhzF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774">
        <property type="entry name" value="PHENAZINE BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774:SF17">
        <property type="entry name" value="PHENAZINE BIOSYNTHESIS-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02567">
        <property type="entry name" value="PhzC-PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54506">
        <property type="entry name" value="Diaminopimelate epimerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="79"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="86"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1747926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="605" mass="66643" checksum="4A55597F75344320" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHN8</accession>
    <name>A0AAD9DHN8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHN8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="378" mass="43515" checksum="85B9AAD1B1F81CCA" modified="2024-05-29" version="1">MRNYASAVRGENDHPNTLAKQSTKWTLVQQSKKKLSVSALMNAASKNVLRTSLHVFKNTTKSHQRPVPALQCNSRSNKTHYTGTGTRYKKPPLSEKEVDNYLFRASKFGVSNDTLYSIDELKAMKRRFTHHDGSSHLHVLVLLSNLELDYAKLLQEACNSTSNMLRKTLQAFKYTDSYTVKLERSGKNVYTLVLQLSRQLDRYHEMKLKDIYAKYKCEGFAKWLGGMTGWYYSPGVNEWGQFIIARLNDLQSVVKTYAPPELLYCFPGESKTLVWCKRQDLWRCVIDVRFFVERAKKKLHTSSARRMKLLQNSDDGPDSLVHWAHHDPQNNYPLTVVTAESMGRLVELLVELLLQVLPHDAEEKLNGILAALFRKKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DI59</accession>
    <name>A0AAD9DI59_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GTR/RAG family GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_003065</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTR/RAG GTP-binding protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DI59"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990131">
        <property type="term" value="C:Gtr1-Gtr2 GTPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010507">
        <property type="term" value="P:negative regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11384">
        <property type="entry name" value="RagA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000488">
        <property type="entry name" value="Small monomeric GTPase (Gtr1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.190">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006762">
        <property type="entry name" value="Gtr1_RagA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039397">
        <property type="entry name" value="RagA/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11259">
        <property type="entry name" value="RAS-RELATED GTP BINDING RAG/GTR YEAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11259:SF1">
        <property type="entry name" value="RAS-RELATED GTP-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04670">
        <property type="entry name" value="Gtr1_RagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="269"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="321"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="273"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="321"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1746458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="431" mass="47660" checksum="7ECBAA7278B8B2F0" modified="2024-05-29" version="1">MAKKKVLLMGKAHSGKTSMRSIIFANYLARDTMRLSPTLDVEHHHVRFLGDLVLNLWDCGGQDAFYESYFERDRETIFRSVELLIYVFDIESDCPEKDFDHFAGVLEAMEENSPDARIFVLVHKMDLVAEEERELILEDRKRLIEESCLGVGVQHFQCFGTSIWDETLYKAWSEIVTNLIPNIGVLESHLSDFCRICDADEVVLFERATFLVISHAQAKRDNSDDGGGGVKGLITDEKEQQHHEEGNEDGADINGEAGWAENADDLAAEKQGEMSTSPHSQLSSPIHDAGDDGMATPQTPASPGGGNATHTAAGSTAVVSNQVGGKASSNQITPSPTPQFDAHRFEKISNIVKQFKLSCGKAQSQFQGMDVRNSKFTAFIDAFTANTYIMVIVSSKTQVNGQEWGTGVHKAATLLNIQKARSHFEQFIPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DI73</accession>
    <name>A0AAD9DI73_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_003110</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bZIP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DI73"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14811">
        <property type="entry name" value="bZIP_u2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47416:SF8">
        <property type="entry name" value="BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTOR E-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47416">
        <property type="entry name" value="BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTOR F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="9">
        <location>
            <begin position="430"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="76"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="146"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="279"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="558"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="448"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="90"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="164"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="195"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="279"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="314"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1746503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="738" mass="81487" checksum="33FCDB2A832218B9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIP3</accession>
    <name>A0AAD9DIP3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HPP transmembrane region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000616</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIP3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007065">
        <property type="entry name" value="HPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058581">
        <property type="entry name" value="TM_HPP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33741">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN DDB_G0269096-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33741:SF5">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN DDB_G0269096-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04982">
        <property type="entry name" value="TM_HPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="HPP transmembrane region" evidence="2">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="74" mass="8056" checksum="7B36E4C1429218F8" modified="2024-05-29" version="1">MAKLGITHPPAGAASIVFSSMKNQWANMGIFLCGVSITIINAVLINNMSDKRQYPTSWPYLSRAKAKVGICKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJY8</accession>
    <name>A0AAD9DJY8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000903</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJY8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="305"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="418"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="453" mass="50870" checksum="D7BCDA86C5A1F3B0" modified="2024-05-29" version="1" fragment="single">DGSISEHGSVASNTGSIASTRSALKQSKYKVCQKKMQQHLNETENVTTMSMDLDIDEDSDDDEEKPTVIQPPQPPPQPVEVEPIHHQEPRRKHLGESRDRDNRSKEKRRSKRPQIRSSLVQVSPNTNRPDPEEFPCGESLGSYQQEMPRSLRSTSYSSGPYTNVVVCPPTNFDDEVSAISFMESVKYQPVHSHNRQQQVPIAEDSENTQETNECINTNNYDSKGRCANHPQIRLRKKKLFGRGWKVLMNACPDCCVDELRRFKSSEASKRRQFRSSSLEDQIGGSVRSAPLPLRDNSIKSISDETASLTASNSSSSSDRSAKNSRQERVGMHQVVPATEVKEKEVIFVRQMQWTDERGSVGMYTGEVDSNFTPSGNGSLQYTDGMVVEGKWKRGEHRPKRRSRSSSRSRSSRSRSQSKTRVSSSSGRSRSSSRSSVTRTRSRSVSVQPVASHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DKB8</accession>
    <name>A0AAD9DKB8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CBS domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_000467</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DKB8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04623">
        <property type="entry name" value="CBS_pair_bac_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044725">
        <property type="entry name" value="CBSX3_CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051257">
        <property type="entry name" value="Diverse_CBS-Domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43080:SF2">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43080">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN CBSX3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="3">
        <location>
            <begin position="157"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1748528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="234" mass="25536" checksum="10BFB3B6C9E1ACFF" modified="2024-05-29" version="1" fragment="single">HIIIIDINSAKRTPRSVANIITPSKRRTTRTTIMLSACASSITRASARTLSQHRLQASAAVSSHFAATTSKRTVTSKVGDRTAEHAWNKSCYSGMDYTISEDATVFEMVEKLAAYDVGCLVTKDEKGNLSGVVSERDYVTKVALLGDSSEDIPVKKISTKAANLVMARPYDTVDACMDKMLSRDIRHLPLIDDMGQVVGIISIKDLIKECLDEKEHTLNQLASFAVGEGGHFVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DKI0</accession>
    <name>A0AAD9DKI0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">MPN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_001069</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DKI0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005366">
        <property type="entry name" value="EMC8/9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12941">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12941:SF10">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 8_9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03665">
        <property type="entry name" value="UPF0172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1749130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="218" mass="23682" checksum="C30C06937A8493E0" modified="2024-05-29" version="1">MSTSNQHISVSSLAETKMALHSAKHGLSNPIHGIVIGKRSGDDNNVLEIVDAIPVCHEVPTKPIVDMALRLVDAHLQQQGGDDLTIIGWYTSNASTLDDDTPNLSACRIASSMSDNCQDGGDNFILVLVTTSGLLAAVSKDSDSSLSLCRVFQKDTKTKTFSSEVNSSFVTQENDTSYIISKALSKEMPIYDFVDHISNYGSEDWNNMDWIKNGAIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRY6</accession>
    <name>A0AAD8XRY6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000066">
        <property type="protein sequence ID" value="KAK1732484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRY6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="336" mass="36825" checksum="FDDEC5698DC1407A" modified="2024-05-29" version="1">MALSKHSDTNAENERRRREAGNDSFEGVSIMVGCYCFQLQSGNEDDCPCQVVFEEKNRQVIALATARNKARENGRQSGANPPPEGTTTALFYNHMKGLIDNHTVREAQNADGRNQDQMIQDAATLVGHDMIGDPYIVSNATLRQELQHDIPRNTTVQFRGNNGGAAQTLTLAQARKQIKQSRKEKKDGAFDAPTYGGPSQVPFYSNRTAHAPLPATAAHAPLPATAAAVSAQREGLPDPNRAHRNKLSPVPLPVPLPIPTESNQPGPNSMATRVRKRCTKIILDKSTSPETKKKVKPIYQRLSKQSPSILRTIEDDLEVESSQEAVSQLTELFGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XS04</accession>
    <name>A0AAD8XS04_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Circumsporozoite protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_016904</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Essential sporozoite protein. In the mosquito vector, required for sporozoite development in the oocyst, migration through the vector hemolymph and entry into the vector salivary glands. In the vertebrate host, required for sporozoite migration through the host dermis and infection of host hepatocytes. Binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes.</text>
    </comment>
    <comment type="function">
        <text evidence="5">In the vertebrate host, binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes and is required for sporozoite invasion of the host hepatocytes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the plasmodium circumsporozoite protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000067">
        <property type="protein sequence ID" value="KAK1732423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XS04"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051860">
        <property type="entry name" value="Plasmodium_CSP_Invasion"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44826">
        <property type="entry name" value="SPORE COAT PROTEIN SP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44826:SF3">
        <property type="entry name" value="SPORE COAT PROTEIN SP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0748">Sporozoite</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042277743" description="Circumsporozoite protein" evidence="8">
        <location>
            <begin position="29"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="25"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="66"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="145"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="209"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00033726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00045806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1732423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="223" mass="22851" checksum="FF87F53F92CE0206" modified="2024-05-29" version="1" fragment="single">MSTLVIRHEVPTPLILVVIAVLSTPASSQTDAPSSEPSLQPSKSGQPSSIPSRNPSEEPSSRPSDEPSSQPSLNPSKSIQPSSEPSFSPSKSNQPSSQPSGEPSDEPSSAPSLIPSKSAQPSSQPSLIPSESRQPSSEPSREPSSEPSSQPSLSPSGSVQPSSEPSLNPSFSTNPTSEPSSEPSSQPSSEPSLVPSKSVQPSSEPSLVPSKSAQPSSEPSSEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSQ7</accession>
    <name>A0AAD8XSQ7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_016123</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000053">
        <property type="protein sequence ID" value="KAK1733146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSQ7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="15"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="80"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1733146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="300" mass="33564" checksum="28544C8CA2B306F7" modified="2024-05-29" version="1">MSRNSEEQAADMMCCALCGTAQVDDIKLKTCTACKSVRYCSIKCQKEHRSQHKRACKKRAAELHDEILFKQPESSYEGDCPICFLPRSLDQKKSTMMSCCSKIICNGCVYSNDSRIYQEKLVYACPFCRHLDPKTKDEEIKNIMKRVNANDPAALLQMGLRRYEDGDNDSAFKFVKKSAELGDAGAHYQLACFYFEGKGVQKDVKKEVYHLEQAAIGGHAKARWNLGAVEKKNCRMGRAIKHMIIAAKLGHDDSLDALRNGFRGGLVSKEDFASALRAHQAAVEATKSSQREAAEEAEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSZ5</accession>
    <name>A0AAD8XSZ5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016134</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000053">
        <property type="protein sequence ID" value="KAK1733157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSZ5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="333" mass="36963" checksum="DE6877BC57AA5002" modified="2024-05-29" version="1">MRRSHSSKTHFVHQQQQHASVTDDARWGASMSNTNNPLNACAAAAGRSLLNRPTQINKTALRQRRLSEHNEVFPASAAETPLPPIRRTGTDLTLKSCLSSSSQTSMLQQSMHDLHRRRTTTMTDSFEIAAYNKNINSKIRRGAVSSSALLFANNKTNNTSASRNEEFKPITTRNVSFSHLQVREYEVTLGDNPSVSGGVPLSLGWRYNPKERISKLDSDDELGSGACGGGYTASSLIVDFDGSSNIDLSSKSSPTRRRSLKLSDRERHRRLSANPNVSAQDLQSVLQAVSSIRMERKESLDELRQERMMRQQQKLQMQTGSGSMGMGLSRRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XT61</accession>
    <name>A0AAD8XT61_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GDP-L-fucose synthase</fullName>
            <ecNumber evidence="3">1.1.1.271</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_015930</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; GDP-L-fucose biosynthesis via de novo pathway; GDP-L-fucose from GDP-alpha-D-mannose: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.271" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000050">
        <property type="protein sequence ID" value="KAK1733371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XT61"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050577">
        <property type="term" value="F:GDP-L-fucose synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05239">
        <property type="entry name" value="GDP_FS_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00956">
        <property type="entry name" value="GDP_fucose_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028614">
        <property type="entry name" value="GDP_fucose/colitose_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43238">
        <property type="entry name" value="GDP-L-FUCOSE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43238:SF1">
        <property type="entry name" value="GDP-L-FUCOSE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="7">
        <location>
            <begin position="6"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1733371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="316" mass="35588" checksum="E4D957198B7204FB" modified="2024-05-29" version="1">MTNSTILVTGGSGLVGQAIKAYTDENSQPGETWIFLSSKDGDLRVRGDTDKIFDKYQPTHVIHLAAKVGGLFANLSQKVEFYRENTLINDNIMENCRLHKVTKLVSMLSTCIFPDKTKYPIDETMLHDGPPHPSNEGYAYAKRLIDTMNRAYAEEYGCNFTSIIPTNIYGPHDNFSIQNGHVIPGLIHKCYIAKKEGTPFTIWGSGTPLRQFIYSLDLAELTVWVMRDYHSPDPITLSVDESAEVPIKDVALAVAKAMKFEGEVVFDTTKADGQFKKTACNKKLRSYRPDYKFVSMEEGIQKSVDWFLANYETARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XT79</accession>
    <name>A0AAD8XT79_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lysine methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_016191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000054">
        <property type="protein sequence ID" value="KAK1733053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XT79"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF97">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="336" mass="37366" checksum="FB9EB67A3CB77D37" modified="2024-05-29" version="1">MAYQQYMQKERHRPPSKGFQCREDIEKEDHLTSVIFKCNLPHQQQHVVEFNCREPSCGALEGEEEGAVLSEDDYAVDPNFFDEGYSMAGSTGFKVWTGSRLLIEALTWPQDTDCDRLKEIQECVKNVGGTRIIELGAGVGVVGTYLSAVGSQVLLTDLTTLVENAIDTNLERNERILSNMPIDDDNDKSCPSWLVNGQRIGKGWADATPLDWTKPISEQLTDEQASIDFIIASDVVFLASMMKSLFDTVEALFQTSKGNKPSFILSFQKRDAQDGTDSVAFTTVDGVLAAVKERGWTIECLAWRTVAVKREDETGSVKDDTSEVFVFEIKDDTSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTE4</accession>
    <name>A0AAD8XTE4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Amino acid ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_016367</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000055">
        <property type="protein sequence ID" value="KAK1733036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTE4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051455">
        <property type="entry name" value="Bact_solute-bind_prot3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30085:SF6">
        <property type="entry name" value="ABC TRANSPORTER GLUTAMINE-BINDING PROTEIN GLNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30085">
        <property type="entry name" value="AMINO ACID ABC TRANSPORTER PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1733036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="450" mass="50038" checksum="50545CCE4269CD8F" modified="2024-05-29" version="1">MGFSFSTPYLYGGMTFNGVPEFVKCADDLSAVGDCAGILICSILGTTWYDTTKELFPASNIVLTKDQLESIKNLIDGKCNVIQGEQYDAPEVVVRGYGYDGPYGQGMTSFTKDPLAMVTRDGDPEFAAFVSFVIRTLFLAEKENITMMTADTFAQTQSVEAITFAQSVQGISFAQATELAQYNGLRQSLAAVGNYGEMYTRHLASISPRLEMNEINNEETTGFLYSHPFGKVDTVGPEPINGGVIERILQRGFLRCGIPSRNYPDGLEDWQEARYDKSILFHMEFCRALSASVLQRTPDNVSFQSYSDYDDIYLALENGDIDVYSGGAVDVDSDFLLPGMAFSSPYFYEGGKAFALVTQDVDVQWADFVYWVTMATIYAEENGITQNTSNEMPLVNLFGTDMERLLRDAILAVGNYDEMYRRVFGQNATRVGLNMLNASPFGPQHYPYLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTL6</accession>
    <name>A0AAD8XTL6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015687</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000046">
        <property type="protein sequence ID" value="KAK1733644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTL6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAP" evidence="2">
        <location>
            <begin position="40"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="391" mass="45215" checksum="11BA3CFD18A5423C" modified="2024-05-29" version="1">MDFGYNSVDEQEQQEEEEEVMAQHGNDPSSESLDTERDLLEELTVKELKKRLKEEGLRTVGNKDELIERLLRPERETIGQLKNGIAHCLLTADDILVMGLSWVNINEKRQQVRQALNVERFKSFFGVEPSTLKDVYSKLVDLCDVNDVGLKEFLMLVEWLNKYDTESGMTSRWGWDEKHIGRKLKKVGKQMQSASKAVIVLDLNNFDPKEVIIVSVDCVNYATTEFRLDPSTMWFDHKSHGPGLKYEFGVCVHSPYCVWIRGPFPAGKYNDLSVFLGKESEGQPQAEWNRDALFWKIPSGKKAVADRIYAGCPQKVMVKRDGHPDWVTEYLDRIQNRQETYHRRLSSFNILSDTFRHGKSTSEKMNLHRMAVDCVAFIVHHDLEYHPLMEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XU65</accession>
    <name>A0AAD8XU65_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_015232</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1733974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XU65"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1733974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="372" mass="41523" checksum="FB70188FE7983798" modified="2024-05-29" version="1">MERRDFDYYEARGDVKLEDITSCENNAEILRRLRDQDTYLDAINITDDYGIADDEDNDWFTAGEGDDLGWLGYFIGKSKYLEELFIYSWEGVEHIEALIDGINRNQSIKSLHIGTDLRGTSFQHLRPFFRNNNNLAQLTLDFEVGLECAQSIVLTLGESRCQSLTNLHLIDCNLGAEGFVGIATALRAYPQLRGLYLQNNNIGLMGCIALGDTLRGWGESNLKYLDLDGNAIGDQGLQALATAMTNSTLEQLYLSNNLITAVGLRSLSDYFQSESCCLKSLYLSRINFGDEGAVALAEGLNGNKSLTSLYFDPHQSGITHDGWAAFSKLVCDTSNVNNIYLSNHIIRTIGDHEMFSTPLEIRQFSRAILTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUM3</accession>
    <name>A0AAD8XUM3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015598</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000045">
        <property type="protein sequence ID" value="KAK1733743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUM3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="127"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="345" mass="39685" checksum="3995110CE8849657" modified="2024-05-29" version="1">MNYSLSRSVARAATRRELAKPPVAIDTITLFVDTSSQQPSNLAEPKSLRMFSSSHNNKIDGHQLSAVSVDLHAAQTKLLKEASYLTKTLYRKFLKSIQSLARGNERDETDFSEREQSELDQLDEFYSSSTTKDSTSNNTNNRVSLMAPPVNRQNELSSRANYYQAFTREHFDGHWNLLGKHGFHLGEEGNMRHGLGNAGGGQEGNRYEGGHHHLGGQMATQYSSHQVVARSSCVDSDDSSNKVIPQQQQQQQQYYMWREEQIEQFTYLITSGEEKRQWILNDYEFKDPCSKHWPEELRTRIRQFEESANALVKEMYRRRGWIHSSDHQQYARDASEDSDSDDDDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV13</accession>
    <name>A0AAD8XV13_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015388</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV13"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="52"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="159" mass="17722" checksum="598E47D6C19B1A4B" modified="2024-05-29" version="1">MKSKEKQAKKAASSNAKIKATKKSGGGGLDEIDSLFAQKKQSDKELQQQIIHEKEQAKIERKRRKQARLEEEAEEVALRGGGALSAAAGGECDICPETLHSKAMKLGKLSYTRSDLEELNDKSKSERKDKWASDGLGEYLMGKDLQVERMMDIVFSRHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV76</accession>
    <name>A0AAD8XV76_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_015301</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1734043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV76"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1734043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="614" mass="68305" checksum="9FC33648E82B8C4F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVG4</accession>
    <name>A0AAD8XVG4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heat shock factor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_015009</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000040">
        <property type="protein sequence ID" value="KAK1734242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVG4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000479">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF206">
        <property type="entry name" value="HSF-TYPE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="6">
        <location>
            <begin position="101"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="192"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="364"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="450"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="451"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1734242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="506" mass="52513" checksum="ED50FB576EA51520" modified="2024-05-29" version="1">MHKVELKEQEESNNVQPKASSVVNRPSSQQQVVQTGQVDAHGSSSGITGPSRSNDSEDAAYVYRDFAQEEDPTERINANYAGHSSLISHEDETTRSLASQKLPAKLAAMLSDPDLITCITWLPHGRSWKILNRDLFSSYALPRYFGHTNHSSFVRVVNAWGFRRIISGPDRDSYYHELFLRGKSSLYSRMKRLPNNSTAGSGGGRKSASSQQVVNRRRQQQLHQEKSLDFYEISKNSPLPENMWQYRPQAMNNGGVGSGRMGGAGGGHHSSLGAFGAAAGGMGGMMGGMVPAAAMGMHQHHAGNMAAAAYHGGGGGMAPPNPMMGGSFAGPGGAAAAAWNVPGGASGATASMMGMNRRPMSLSFDGSAGGGVGGPDSISRGVHNSTSSSRQQNAPQLLAAAALRQAPNPNETSAGASSELQSLMNQNKLLQTLLVKTQAAVVAAASVAGRTSGGGSGGASGGSGYPYVQAQQHYNERGSTAAPPGSSFSMPPSAGGGGNDGRRGGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW90</accession>
    <name>A0AAD8XW90_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_014072</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XW90"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050502">
        <property type="entry name" value="Euk_RNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025">
        <property type="entry name" value="OS02G0815200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025:SF1">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="218"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="185"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="296"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="187"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="216"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="313"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1735006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="333" mass="37422" checksum="4CC5B5686C9074E3" modified="2024-05-29" version="1">MNTAPRYQQQQQQHDQKGAGEIRDGGYHYYYGSHDPYGDSLSVILASASSLIIRAMQAPLQPEVVQHGQAPSPQQQPISVTMTPSSSACAWERSEPHYASYCNEASVQAQFYTPSHSLDGFMSQVHHLQPSISPPYTQHQPVPVQESFKYPSVYDVDVLRTSAPYPVQQVQTQAQAQAFSYDRDIHQPSSQSDSDSDPSPRARESSAKSPPRRKGNGKELHVRHLPSDMTEEELRDLFSPHGVVTRASIARHQSGKSRGYAFVKFKLQSAADNAIMRLDKYEIRGKLLHLEYAMKQPRPRGRVTTSDEECQTKTHRRRQGQGQRIRRAASAPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXM2</accession>
    <name>A0AAD8XXM2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GDA1/CD39 NTPase family protein</fullName>
            <ecNumber evidence="6">3.6.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_013966</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GDA1/CD39 NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXM2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004382">
        <property type="term" value="F:GDP phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:ribonucleoside triphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045134">
        <property type="term" value="F:UDP phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009134">
        <property type="term" value="P:nucleoside diphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.150">
        <property type="entry name" value="Exopolyphosphatase. Domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000407">
        <property type="entry name" value="GDA1_CD39_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11782">
        <property type="entry name" value="ADENOSINE/GUANOSINE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11782:SF83">
        <property type="entry name" value="GUANOSINE-DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01150">
        <property type="entry name" value="GDA1_CD39"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="348"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="132"/>
            <end position="136"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600407-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600407-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1735352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="384" mass="43110" checksum="F0E3D07AF1208660" modified="2024-05-29" version="1">MMGYSYGCVVDAGSSGSRIFLYRWPKQKDGPTEEVFNEEITPGISDPEHGLAALQELVTLARKALPQYHGGNINENKRLAAYLRLYVSRQVGKSHQWREEGIYDWLTINYMKNGGALPDRLSPTYGALDLGGASTQISFNEARAKHSRHIAATNKSNSNNPCYPVGYVDEITNLNGSSNWDECLLSVSQLFDPANCVDDGESCFDSASLTQLASHEEKFVATSAFVFAWDFLQLKTGANTDDLATLNKQAKQICNMEFSQQLRHYRQYKRRSNGSSVRTTTKPHAQCFNAAYSYHLLSAGYSMPITNTPIEVNDIKSWTLGMMLVEANNLTKISNGELYSNLLYSYEYVFAGSTLVLMLLTSLVWRRKRRQVHYLPHVTKSQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXX0</accession>
    <name>A0AAD8XXX0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXX0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="268"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="480" mass="56449" checksum="C7F2B43E01B5AD37" modified="2024-05-29" version="1">MKPSIDLQDLASILFPLVKSSATEVVLNALDEAWALVNVSGIKQVNNTNLSLHLFDKMLNQMVIQRLFARSNSIWGRGSFYLLILPLGRGFYNVTLLEVIKHARLEQTIRDKLARDDCQKRRQAYRCWLEIFRRQKSLRYTFDAINCMVAINLKTRGHRALTHSRMCLARLKLQQLLLAYTLAVIKVQSLIRGVLARRLALRRLMTLVEKERMDNASKMKWYAWDRGMWCLTRLQSHARRKNAVTLVNQLRQQRRREAEVRHAMDSRNAAFRRERKLYQRQLEEFYRQMKEDHDTNKQNEAKISQDKIRLRTLQRRIKNEELKSQEPDKVLEENLALSSGNAIVDVAKIREHYAHCLDRPANRSEKKTRSDARKRIKHRVTEVLARADSKNIPMETKEAKVIAREEVLHMIGEEERARLHDQMNKAFAKREHDKVMMRTKVDTAKREAQARATVYAVSVVSAACRRWLARKEMRFMLGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYH9</accession>
    <name>A0AAD8XYH9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013523</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYH9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="86" mass="9437" checksum="15C6A22AAF93A3CC" modified="2024-05-29" version="1">MTSKSSNGSGTKRQRTSPHTPITVNDLLSADLWCGIADFLPKTSRILLAVALTAPPASFRESAWLERTAERCQQGNHFIGRRQGII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYX6</accession>
    <name>A0AAD8XYX6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013547</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYX6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041903588" evidence="1">
        <location>
            <begin position="22"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="238" mass="26158" checksum="4BDDAE06943CB222" modified="2024-05-29" version="1">MQSKTLFFALLAAVQKVSVVAFVPPKATKIVLPSAAITTSRSFEPNAVINPRGSTALSGLLTPLADAPISTEGLTFGWVVICAAMTPYVIQLVAPQPLGFFLANYYGGQDIAELKQDGYTNEQIEDLVESGRVAEVKWKVRFAALCLAVTTIAFFEVNDGVDAVRVLRDSYIAWGIFYVEATRLIREQALEEPSILKIESRFGIQLWHVLVTILLWASISETYTGNAVRTFVTDIFTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZD5</accession>
    <name>A0AAD8XZD5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012753</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZD5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1736731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="84" mass="9744" checksum="AB62A633D4660BCA" modified="2024-05-29" version="1">MTNNSNPEEYVTLSFKLMDWSHMDFKRTLNTSTSIVTIKDIINHHHGSISSIVICKHSFEEKNELRHAYATLKDYGIRGSETWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZR9</accession>
    <name>A0AAD8XZR9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013043</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZR9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="187" mass="20461" checksum="7ABC5DAC86B7D5CA" modified="2024-05-29" version="1">MANNNLPPGWGDRHNKMSEHDMKLGGMAATKFAKNSYSDNPTSAAAVGGSYQNSDQVRDFYLNGSQKKKDGESNSQTTTPDFWESRQKQKELQVKQMGVFAKNSDHSLKQHQSIESLQSAGVNEKACIDGDEDDVPEPEVALVQIATHALDALAKSLSKRNVSIPMEDRASFAKAMKQAMDALAKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y157</accession>
    <name>A0AAD8Y157_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vesicle-fusing ATPase</fullName>
            <ecNumber evidence="4">3.6.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_012120</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="4">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.6" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y157"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005795">
        <property type="term" value="C:Golgi stack"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035494">
        <property type="term" value="P:SNARE complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000154">
        <property type="entry name" value="Vesicle-fusing ATPase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039812">
        <property type="entry name" value="Vesicle-fus_ATPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23078:SF3">
        <property type="entry name" value="VESICLE-FUSING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23078">
        <property type="entry name" value="VESICULAR-FUSION PROTEIN NSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041920959" description="Vesicle-fusing ATPase" evidence="6">
        <location>
            <begin position="25"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="7">
        <location>
            <begin position="398"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="7">
        <location>
            <begin position="696"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="230"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="320"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="335"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1737253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="939" mass="100862" checksum="80D5F882F3CFBB04" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1I9</accession>
    <name>A0AAD8Y1I9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011987</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1I9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="507" mass="56235" checksum="F95DF7CA329A6F86" modified="2024-05-29" version="1">MGHKKGKQAGHFANKKANSLHRYTLNDYASEADEFRNPVRTTFRAEDIGRWHRDGTGVGGRDKWSTLFSSKSSSSSTTGLQSNAISNNQSAAVGRRMAHLRFLLEERRIEDRIDDRQLRLRLQRQRMRKLHLEEGYNICNTNTSNEERHEPGWLLTHDMHNHDKHDNNNINNIPSLQKLAAQRLGPLLPMYVAACGHEYVGDALQSVSSEVLCEISIALANSPQSEATITDGVIKSLVQSGVASRLVLKGTGTPLEDDCNGNEGNIDDDEDDTHLLSDVGLLSICPRIQSNHVDTTTFNDDDGDDSDSSCDNWETIVHDIATVGCIHLTRLELIDIPLDTASSNSSLGGISIDALRKVLRTCPGTTHLSLSGCFSNCHQNTSLIEQAHDANMLIGGSFSSTSTPQLFDQFRCNDGDKVSGLDDLLPDLRVLDLSYCNWLTSDALKLFLLKCKQRDNGMQGIATLQHVNILGCDSLITPSFLHWINEMRNLGLLDGIELSRQQQTRDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1R2</accession>
    <name>A0AAD8Y1R2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA/RNA-binding protein Alba-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1R2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.20">
        <property type="entry name" value="Alba-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036882">
        <property type="entry name" value="Alba-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014560">
        <property type="entry name" value="UCP030333_Alba"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31947">
        <property type="entry name" value="DNA/RNA-BINDING PROTEIN ALBA 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31947:SF36">
        <property type="entry name" value="DNA_RNA-BINDING PROTEIN ALBA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="181"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="258" mass="27354" checksum="478710D34C552253" modified="2024-05-29" version="1">MSNRGEGGQNSDVGLTPDRKPAAAQSSSTIPPSGHSTEAAQDQLSSLSLADKPTAKGPLTPSTLETKPTGSSSVDSSEQDRDETNATQTESPRQTIAVSVSKGPSAFFNLARKFLVTDEMCDLSALEGAIVSAIDAAHLLERSKIATITRLQTSYVAVEPKKKKDRAASISDQPTSYGSLPTPAESAAPAAAAATSRIDRSQAVTIDSPSVPEHQNLSEGTLRRSRIVITVKRTEAYVQWLKENPIQDIHSGDDDDRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1W8</accession>
    <name>A0AAD8Y1W8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012182</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1W8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13369">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13369:SF0">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13679">
        <property type="entry name" value="Methyltransf_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="616"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="578"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="587"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="850" mass="93893" checksum="3CB9D9D0E8FDD1FF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2J7</accession>
    <name>A0AAD8Y2J7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_010926</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31403">
        <property type="entry name" value="PHOSPHOLIPASE A1-IBETA2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31403:SF7">
        <property type="entry name" value="PHOSPHOLIPASE A1-IGAMMA3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1482"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="domain" description="Fungal lipase-type" evidence="10">
        <location>
            <begin position="1210"/>
            <end position="1363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="253"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="485"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="543"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="782"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="838"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="9"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="489"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="547"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="586"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="610"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="782"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="792"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="850"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="862"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="882"/>
            <end position="893"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1738257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1509" mass="169122" checksum="ADDA040E62A89D3B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2Q9</accession>
    <name>A0AAD8Y2Q9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2Q9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="109" mass="11510" checksum="7A2C934AFEF486FF" modified="2024-05-29" version="1">MFKACTDCHQRQYDKLKAKCTAMSHEERLALAKRTNAAAMGMIVAGFGCFGGLVGGLWHQMGAGALGAGFGGACGLWFGSCGVFEEAKLILQFDKELTATAAEENEEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2R4</accession>
    <name>A0AAD8Y2R4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Multidrug and toxic compound extrusion (MATE) family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_011031</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2R4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044644">
        <property type="entry name" value="DinF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42893:SF46">
        <property type="entry name" value="PROTEIN DETOXIFICATION 44, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42893">
        <property type="entry name" value="PROTEIN DETOXIFICATION 44, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042141768" evidence="7">
        <location>
            <begin position="22"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="400"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="442"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="472"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="503"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1738362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="543" mass="58098" checksum="68E12237D4CD0FD4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2T7</accession>
    <name>A0AAD8Y2T7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_010639</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2T7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1738609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="139" mass="16321" checksum="1F19867B4E873E78" modified="2024-05-29" version="1">MNDLRSSLQALYDEYINSDECKRKGDDFTLPVSISKRNYYEEWCRKRGWEPIKTDTANGQYAKVADFELLDGYYRTEEEESLAEAEGRYVVGVAKRVVAFTNFMYCWNNEFPNMKTQGRVGKGMFIGERYGSGKWDRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y397</accession>
    <name>A0AAD8Y397_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y397"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042060898" evidence="2">
        <location>
            <begin position="22"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="114"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="322" mass="35446" checksum="2F20007B5A55D137" modified="2024-05-29" version="1">MKKPVALTPIALMLCPSLVMSLQIITPPLKEQKSLVPSFSSIKQPCYHTTMRHRRKNSSSFATTAPVTTAASSYTTLFSTPTNAIDAEIIKYKRTLLFPSNTKRRRNSGSPLHSSTSSNENASSPSEEDTTTTTSPSESTISFLKAVDNFGMSLKPLAIQAYEKSNAINGESKQQQTNNKQTSLKSLLHCVKSNILWMMYIIYRGYRGFFVILPAVFREVYRQLEESDLVMDAYGDEEVENGGGSSGGEVGEKKPLRLRTRITTSILSSILTMSYVVSGGIRVLGKFIQTFTNTTSVESSLEAAADEMADNEDKLAGRYKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3C0</accession>
    <name>A0AAD8Y3C0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">General negative regulator of transcription subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_010803</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd20710">
        <property type="entry name" value="NOT1_connector"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000012">
        <property type="entry name" value="Ccr4-Not transcription complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.840:FF:000003">
        <property type="entry name" value="Transcription regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.840">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 1 TTP binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007196">
        <property type="entry name" value="CCR4-Not_Not1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055454">
        <property type="entry name" value="CNOT1-like_NOT1_connector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032191">
        <property type="entry name" value="CNOT1_CAF1_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024557">
        <property type="entry name" value="CNOT1_dom_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032194">
        <property type="entry name" value="CNOT1_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032193">
        <property type="entry name" value="CNOT1_TTP_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038535">
        <property type="entry name" value="CNOT1_TTP_bind_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040398">
        <property type="entry name" value="Not1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13162">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13162:SF8">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25097">
        <property type="entry name" value="ARM_Cnot1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16415">
        <property type="entry name" value="CNOT1_CAF1_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16418">
        <property type="entry name" value="CNOT1_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16417">
        <property type="entry name" value="CNOT1_TTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12842">
        <property type="entry name" value="DUF3819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04054">
        <property type="entry name" value="Not1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 HEAT repeat" evidence="11">
        <location>
            <begin position="331"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 TTP binding" evidence="10">
        <location>
            <begin position="540"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 CAF1-binding" evidence="9">
        <location>
            <begin position="803"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1" evidence="8">
        <location>
            <begin position="1107"/>
            <end position="1262"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1-like NOT1 connector" evidence="12">
        <location>
            <begin position="1401"/>
            <end position="1543"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-Not complex component Not1 C-terminal" evidence="7">
        <location>
            <begin position="1768"/>
            <end position="2118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="711"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1027"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1313"/>
            <end position="1339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1568"/>
            <end position="1598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="711"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1039"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1316"/>
            <end position="1331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1588"/>
            <end position="1597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF25097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1738773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2135" mass="234398" checksum="F8338A554F0AF32D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5Q2</accession>
    <name>A0AAD8Y5Q2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF285 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009149</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5Q2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005046">
        <property type="entry name" value="DUF285"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011889">
        <property type="entry name" value="Liste_lipo_26"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02167">
        <property type="entry name" value="Liste_lipo_26"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03382">
        <property type="entry name" value="DUF285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="276" mass="29851" checksum="9572B5FBE8159FC3" modified="2024-05-29" version="1">MAAMFHASAFNQDVSAWDTSKVTEMYGMFNAARAFNQDISAWDTSKVTNMESMFSYASAFNQDLSVWDTSSVTNMNRMFEEARAFNQNLCAWKDKFPYITAFQIFSDSGCTYKATPVQLIQGPFCAGSAADCQAYTVEGCPDEFEEGTDYEEGDKMSIISDGEDYGKIYKCKGWPYTGHCKSEAFSPLNTAQACGGEVCWPVAWTYQGGCTGTITPTGAPVFLSLPEPLPSPSPSPNDTYKSANDAKAEKVIAAKAKSAKSKSKAGGSGSSKAAKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6G6</accession>
    <name>A0AAD8Y6G6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-CH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_009023</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6G6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-CH-type" evidence="4">
        <location>
            <begin position="13"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1740073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="432" mass="49136" checksum="46F2CF7EDF2BE456" modified="2024-05-29" version="1">MSSASQSTSVVSITPPDGASCWLCLEEGPDDSGAPLVRDCSCRGHSGFAHLPCRVKYAESKIKDLAKRGAHIMSNMFDGKIFEHCPNCKQEYQNDLYYDMTKAQLAFIEREFIEVDRWYLRALKRRILILDGEKEADRIEGEEISAKMLTRIDKMKNSSDPPLHVLAGVYLDIGRFNFSVGTNRCLEKAKYYLEKARDIFKTSGDRELQLMVKSIEGNIAAVEERLSGGSLPKKTESDLSDFRVRYNCLLQAFGTHDVRSIRMGSHLASGLSLANHTIEASRLLDRLVIISRRVHGSDHKETKNAELWWQRLQLRCVVWIRTDEMYQALRYENDGKSCVMVPSNLDASRNVDDEETFSVPISEILFSLGTPVMLHGLKKAAHLNGEIGDVREYCKLSDRWVVHLEDKNLKPVKVKHENLRIVFDLPDPKNLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y783</accession>
    <name>A0AAD8Y783_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009249</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y783"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="162" mass="18115" checksum="DF9A95794559F20F" modified="2024-05-29" version="1">MQKVLHIMCRCNGGSSRDFNSDDAVNGSAVTSTSTCSRTITISRPTFPEDRPKKSIDTANLNTKDIESLKKSDPFLYFSIPAVHKAAIHSRQIDLPALHADSHSCRVERRSRISFECHTDLLMEEFMEELSGLSNLNGALDDDLDAILGSLTLMTNKEEQRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8M4</accession>
    <name>A0AAD8Y8M4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">SKP1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_008292</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the SKP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8M4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18322">
        <property type="entry name" value="BTB_POZ_SKP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.710.10:FF:000026">
        <property type="entry name" value="E3 ubiquitin ligase complex SCF subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016897">
        <property type="entry name" value="SKP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001232">
        <property type="entry name" value="SKP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036296">
        <property type="entry name" value="SKP1-like_dim_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016072">
        <property type="entry name" value="Skp1_comp_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016073">
        <property type="entry name" value="Skp1_comp_POZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11165">
        <property type="entry name" value="SKP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01466">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03931">
        <property type="entry name" value="Skp1_POZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028729">
        <property type="entry name" value="E3_ubiquit_lig_SCF_Skp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00512">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81382">
        <property type="entry name" value="Skp1 dimerisation domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="SKP1 component POZ" evidence="5">
        <location>
            <begin position="8"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="SKP1 component dimerisation" evidence="4">
        <location>
            <begin position="117"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR028729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1741040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="167" mass="18753" checksum="8AD3511149487796" modified="2024-05-29" version="1">MEVESGTVNLVSKEGDSFPVDTEVARMSELVKGMLEDDSGDDDDTTEIPLPNVKAAVLKKVIEFCSHHKSEPMTEIEKPLKSAVMAEVVQKWYADFVNVEQVLLFELILAANYMDIKPLLDLTCATVASMIKGKTPEEIRKTFNIANDFSPEEEAQVREENKWCEEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9G1</accession>
    <name>A0AAD8Y9G1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9G1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="541"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="565" mass="62625" checksum="45E6AE2283AB1BC9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9P8</accession>
    <name>A0AAD8Y9P8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">U-box domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_007371</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9P8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16655">
        <property type="entry name" value="RING-Ubox_WDSUB1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052085">
        <property type="entry name" value="WD-SAM-U-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46573">
        <property type="entry name" value="WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46573:SF1">
        <property type="entry name" value="WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="14"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="U-box" evidence="3">
        <location>
            <begin position="361"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="586"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="745"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="237"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="588"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="605"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="632"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="654"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="689"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="749"/>
            <end position="763"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1741798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1027" mass="115900" checksum="679BA1DA5383760E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAU2</accession>
    <name>A0AAD8YAU2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">dihydrolipoyllysine-residue succinyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">2-oxoglutarate dehydrogenase complex component E2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_006405</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.61" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAU2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045252">
        <property type="term" value="C:oxoglutarate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004149">
        <property type="term" value="F:dihydrolipoyllysine-residue succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.10:FF:000007">
        <property type="entry name" value="Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050537">
        <property type="entry name" value="2-oxoacid_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006255">
        <property type="entry name" value="SucB"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01347">
        <property type="entry name" value="sucB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43416:SF5">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43416">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="12">
        <location>
            <begin position="78"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="31"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="192"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="195"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1742808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="460" mass="49160" checksum="09EE597FDA6A0AAF" modified="2024-05-29" version="1">MLSSSILRAAARNGSRRSQWTSSILPSSSAVVTSSMPLQQKNDRNNATSQSYYQYNGNSSSSSRSYTTTKSSILQMPIKTIDVPTMGDSITEGTIVDIPVAPGDYVNVDDVVIVLETDKVSVDIRASEDGAVVEIHGEVDDVVEVGSALYRLDTDAEAPAAGGEAPNAVEAPAPVAAAAPEPVAAAAPAAAPAAPVAPPTPPPPAATPPPPSTLNVESITTTLGTRPERRSKMSRMRQRVASRLKESQNTAAMLTTFQEVDMGNFMEMRVRHKDEFEKKHGVKLGFMSVFVKACTSALQEVPAINAYIDDEAKEIVYRDYCDVSVAVASPNGLVVPVLRNTEYMSFADVERTIALFGKKAREGSLSLDDMTGGTFTISNGGVFGSLMGTPIINQPQSAILGMHATKMRAVVDEKGNVVARPMMYLALTYDHRLIDGREGVTFLKSVADKITDPSRLVFDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YB79</accession>
    <name>A0AAD8YB79_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Prostaglandin dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.232</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_007113</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.232" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YB79"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047034">
        <property type="term" value="F:15-hydroxyicosatetraenoate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05288">
        <property type="entry name" value="PGDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041694">
        <property type="entry name" value="ADH_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045010">
        <property type="entry name" value="MDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205:SF42">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE, ZINC-CONTAINING (AFU_ORTHOLOGUE AFUA_7G04530)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205">
        <property type="entry name" value="PROSTAGLANDIN REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16884">
        <property type="entry name" value="ADH_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042255190" evidence="2">
        <location>
            <begin position="25"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="3">
        <location>
            <begin position="331"/>
            <end position="672"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1742548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="688" mass="75715" checksum="23AD0BFBE5E1C8F4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBH4</accession>
    <name>A0AAD8YBH4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_007084</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBH4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008422">
        <property type="entry name" value="KN_HD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05920">
        <property type="entry name" value="Homeobox_KN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 4" id="KW-0371">Homeobox</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="6">
        <location>
            <begin position="185"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="4">
        <location>
            <begin position="187"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="286"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="156"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1742519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="382" mass="42632" checksum="43DD6852C63BF047" modified="2024-05-29" version="1">MNDQYNTAANYNDFEKFIGHSDFARVLELSHFLKEQKQKRRLDGGGNAPSTIKLSSSLMPEQQPCSCVEEEEDVFPFDESAAYIRSTLIGKEKDTSPTPIMKRGMCAITDSLIDETIITLASELRLALSLKKQLAATNAVSFSEDREVDGVIGRVDEDKDGVGHTETQKQASAGKPMDLDSMTEVNTKANANKFTKAQTDTLIKWMIENIDHPFLSPTDIANLTVETGLLEVQVTNWVTNARRRNGKAIIEGDKKPYHFLDYLFLATDREKHVQKNTLSVDLKRNTLESEDNGEESNVTQLSCRADENPQPSYPDLSPIHSPAMFREIFRHENIQLDDLDDSFDEMVRAQTPTPSSAAAATVAYEYEGSESPFDETAADFAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBV0</accession>
    <name>A0AAD8YBV0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006210</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBV0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052420">
        <property type="entry name" value="Espin/Espin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153">
        <property type="entry name" value="ESPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153:SF8">
        <property type="entry name" value="FORKED, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1743589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="320" mass="35560" checksum="90A31B1A3C16DE8A" modified="2024-05-29" version="1">MVSIFKKNNSSSSRKMFKAKMMSKSSLSVTIDSPVSRSDLSIATEPMTIAGLIGNRRWSLLEHLLMDGAPLSIDGPDMAEHAITEHIVVHFAVRFQAPLRTVSLLSKLYPSSISSPDACGRYPVHVACKWSATPDVVNYLVRLNSSACGVQDSFGKTPMHYVAEFYVANYQLPLEMLYPMDESMMQVVKLLKSAAPTSLNLEDDEGCNAIEYALVNDVNIKVIKVMQRACRDDWRQRSKASDEGLRRRHSDLIKDLEELTMTLQEDMRNGGCDNDLKFAHHSALTTRRRGSMVQVSNGRVHVDDPAADPQKPTTVAARSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDD6</accession>
    <name>A0AAD8YDD6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_006145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDD6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1743524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="134" mass="14488" checksum="C6022FF30888ACDC" modified="2024-05-29" version="1">MCPTLTDGLSESNTHFIIAAEIEDGAAHSEDAVTEHTIISYDDGSSRRRGLSSRRVLVSTMAGTFSTISVHTKDGTARGIVQQPGEASKDIIQEQGQRTLISKSEELDTINCADPRCTNAAWQCEMNAVGELFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDF6</accession>
    <name>A0AAD8YDF6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HSF-type DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDF6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="135" mass="14848" checksum="876640909570960D" modified="2024-05-29" version="1">MVCPTKKVSASAPTSRPRSAVAPSDSGSGLVDLLFAASQVETKPKEAEEEEESGGKDKAEEDPFSRHDPEKPSHSLDADAPMNKNFPQILHEILSTPECQSIAHWLPDGFSFIIADKQRIHLIDFGDIVCRLMKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDN6</accession>
    <name>A0AAD8YDN6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004871</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDN6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159">
        <property type="entry name" value="CENTROSOMAL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159:SF60">
        <property type="entry name" value="SPINDLE ASSEMBLY ABNORMAL PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="84"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="305"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="442"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="618"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="744"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="820"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="96"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="150"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="864" mass="95229" checksum="ACA616AEE6CBCB96" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YE58</accession>
    <name>A0AAD8YE58_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC1 kinase family protein</fullName>
            <ecNumber evidence="3">2.7.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006202</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.-.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YE58"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05121">
        <property type="entry name" value="ABC1_ADCK3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050154">
        <property type="entry name" value="UbiB_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566">
        <property type="entry name" value="CHAPERONE-ACTIVITY OF BC1 COMPLEX CABC1 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566:SF118">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="219"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="835" mass="91745" checksum="459960372209F614" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEW6</accession>
    <name>A0AAD8YEW6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase family protein</fullName>
            <ecNumber evidence="2">2.7.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004723</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEW6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012">
        <property type="entry name" value="PROTEIN KINASE-LIKE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012:SF30">
        <property type="entry name" value="PROTEIN KINASE-LIKE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="75"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="377" mass="43217" checksum="2611E67A7667432E" modified="2024-05-29" version="1">MPLRIDSVRTPDDISVDILSEILNEEVIEYRISPLGRGVLSNVQTLDVTLSTRTVQFIAKFRKDEIPLEDLFNVEGAFYHLVDELEEVNAFPFRLPKALATGSHWLLLEYISENVTTLDVYQSCPMNQFDDLIHRLAKMHEYCWVDSSNSTKMAEILNNYSAKLADAPGAGHTLPSSARQEQFAAAWPAVKKRLVPFFSSESLQSIDDIVKWIAASERIELIKNCVEEKRYTLVHGDFHMGNMLLPTEIEGDVDRRSWLVDWSFSGIGNPSVDLVFFMAMNDITAQDTERVLQEYFSVVKERSQLSWNDFLTMFRQCLLNQFIILVCYDSLCRTMADSSSDERMVEVQHAHFDRVNTRCAQMILLYNYNDGNILPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEZ8</accession>
    <name>A0AAD8YEZ8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytochrome b561 and DOMON domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_004587</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEZ8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09631">
        <property type="entry name" value="DOMON_DOH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045266">
        <property type="entry name" value="DOH_DOMON"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23130">
        <property type="entry name" value="CYTOCHROME B561 AND DOMON DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23130:SF171">
        <property type="entry name" value="OS01G0895300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03188">
        <property type="entry name" value="Cytochrom_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00665">
        <property type="entry name" value="B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00664">
        <property type="entry name" value="DoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50939">
        <property type="entry name" value="CYTOCHROME_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041925283" evidence="10">
        <location>
            <begin position="23"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="243"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="288"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="326"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="363"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="392"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="11">
        <location>
            <begin position="210"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="429"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="446"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1745296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="471" mass="52582" checksum="C9617821EA287A5E" modified="2024-05-29" version="1">MRSPALVTLLATLATLVGETYGGGGHSHGNEGYHEHEHEDVDCTANFCKTQLSDDLWKRWHIHVPSDYDPNDDMCAKCEITVQLIYNGYTWLGYGVSPNGGMVGSTVVIGRPSEEQPTIYEIQGKVKMRDALRPINGFNLENASVKYNEGKAQTIMEFTTPFNTFGVTEEDDEYRVGMSLKNPTYFIYAHGNEGNLELDYHGNNKGSRTFENLINPDAAQADDNDASASKMKMSQTKSTKNAWKAHGILAFLAWGVIAPMAISAAVLRDLDWNRLPFKEFLGKFWLHIHAGLNCLNYLFTLVAFSVAVNTSSREMRDHFDHSHPRMGLSIFVLVSFQVLGGLLRPSKKVKSTLRKTWENIHHLLGVTLFCMGVFQLYTGLSMYGERYGKSTSVYYIVLGVLVLLWGSIILGGSLYKLILHIRGGQKEKITEHGSEDGESSTNGDTNDLKFKEEEVGEKVEADVSQDENEVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFQ7</accession>
    <name>A0AAD8YFQ7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SET domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_003625</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFQ7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050869">
        <property type="entry name" value="H3K4_H4K5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197:SF251">
        <property type="entry name" value="EG:BACR7C10.4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SET" evidence="5">
        <location>
            <begin position="1"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="44"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1745701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="567" mass="63749" checksum="7CCAB3981AE32B51" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YG99</accession>
    <name>A0AAD8YG99_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sulfotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YG99"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="321" mass="36383" checksum="1CF0A48C297625FA" modified="2024-05-29" version="1" fragment="single">MTQIARRSTDKEHMAVPWFGIMWIGLTLALSVTYCWSARRQLGVYSPVIPVEVESPVLRAYLKSEEAAAKPPLFDSSFAEYLKKGLSYHIDAYDGGKPYHYKDSSYPHRHANSTLPPWFKKVFPLNKHITPDKQTCFAHVGKAGGSSIGCMLGFLLHCGDDEKTNFQSVPSLLAATTAHSFHREVYDCSDTAANYLFVIRDPLARALSAFNYAKPDLSEKYPFSKKYKDKEIYVDCNFWTLNDFAERGLVKGNNGTSDECKVRAKKALLGTEDNLVHWYFNYQFYYEMVSPDANIIVIRNEHIVDDWNEVETLLGGAADLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGH3</accession>
    <name>A0AAD8YGH3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">START domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003412</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGH3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002913">
        <property type="entry name" value="START_lipid-bd_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50848">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042246946" description="START domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="START" evidence="2">
        <location>
            <begin position="79"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="348" mass="38793" checksum="9C9E1D399E6498DA" modified="2024-05-29" version="1">MKSFATAAIIFISTYSGVDAFTATGKSPLVAAPVATRKEWTTGVEIELPDFDTLFDRVQTASPLAKHVMEGNSGGFESLAGSDSLKWKKLENNERKTVHRIDKLDSYQNIKTPLLRFRSSIKGPLIGERFSHFIMDLEERKKWDDACARNEEVYPIDDLDAVNTILGDEEKYGTCTRVGVGYTQTKQSIISPREQLIIGGMQEFQNGATMLWGTEMEEQHNYLLPEGQRHTRAKSHLFAATLAPTDGGFDVEYLLQMDVGGGVPNFLATPALVDAIKKLFDHTKGYFEGGEGSELDMHLKSLSSRGLDLEVLREIDEIEESFTVEMDFSKEAAHLHDDASLLPLFFTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGQ2</accession>
    <name>A0AAD8YGQ2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGQ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="368" mass="41899" checksum="2432E972FC679198" modified="2024-05-29" version="1">MSDDNNNDEYDETMMNRLLSPSSSSKQNDAITQILTHDDDDSSYMHSIMERRRYIKPQKDDVDEESVASSNAPRLPFQRAVVTPPRRKDRRRVRSSSSSPLRRPINPIILIVLMGLAANWVATRLLDGLIQTDDDEIDADTVNAHVMSQEHITVDDNNVAHQAAYQSDEERMMGMLSLTKLSELPKEEQLSELSELPKGEQLKELSDMRDRYESIWGSKVSEGPNSGQKDQDDEEMKEKLERLRIGIAALKEQLAATNKDEIAESIVNDETTEPQPPSSPFTERFELLRKRLLPLYSEAVPTTPEEHSNTTHPLFNMQSPQFQALNWLSNIDRSQITDEDPHVVQRYALSVLYFATGGPPVDHNTDFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGX8</accession>
    <name>A0AAD8YGX8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_004531</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGX8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF171">
        <property type="entry name" value="NUCLEAR VALOSIN-CONTAINING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase AAA-type core" evidence="3">
        <location>
            <begin position="577"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1745240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="730" mass="80332" checksum="415FD3220FF67380" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YH52</accession>
    <name>A0AAD8YH52_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glucosylceramidase</fullName>
            <ecNumber evidence="6">3.2.1.45</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_003832</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.45" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YH52"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004348">
        <property type="term" value="F:glucosylceramidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006680">
        <property type="term" value="P:glucosylceramide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001139">
        <property type="entry name" value="Glyco_hydro_30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033453">
        <property type="entry name" value="Glyco_hydro_30_TIM-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11069">
        <property type="entry name" value="GLUCOSYLCERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11069:SF23">
        <property type="entry name" value="LYSOSOMAL ACID GLUCOSYLCERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02055">
        <property type="entry name" value="Glyco_hydro_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 30 TIM-barrel" evidence="5">
        <location>
            <begin position="166"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1745908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="843" mass="91308" checksum="D18C88FB96170B1A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHG1</accession>
    <name>A0AAD8YHG1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003434</name>
        <name evidence="3" type="ORF">QTG54_003439</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHG1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="276"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="365" mass="40453" checksum="EA5D25567BA68517" modified="2024-05-29" version="1">MDANIDRTRFPKGIFEATKVNTPTTFIILNNKLSPAADPSDEEAKNKILKIVAVEDGSASVTFSAERVDIDLEGDLKEYRDQVEAGIKWAKAMKNISTNFAAGNIDEAFDNIKDGIKDLIVGNEMYLYLIDELTGEPVRAEGWPIVITTPSEILPRLIPLMQVGMRAESINNGIVGLSPKAWSKGAQESVELLKQESSVEEFGVVHEEVEGGTEEKKSVRGASLRYFVDFLKKYDPGLKQGEKGHFAGLLRIGDPVDGTALWTALTDKAAIEITLTERGENALKELQKQREEEQLKQNEHFKKIENRDSRRSKSLRGDHATGKDLLGVLDEANAIADIISFKDLKLPFVVGIKEVWDRAKSSLTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YI29</accession>
    <name>A0AAD8YI29_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003863</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YI29"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42886:SF53">
        <property type="entry name" value="ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42886">
        <property type="entry name" value="RE40534P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="1">
        <location>
            <begin position="125"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="377" mass="42862" checksum="4C63F7261FB04332" modified="2024-05-29" version="1">MIDVTADEPTLSEPTNTYKHAVYPFPLGLDPRECNGYPPTYIKNEPEHELNFFLTDASDQTQQDEGGKKKRGRIFKKMLRKEVKKNAYVKPESSLACSLAFREEISFEQLQNQVSSSPSGNNFKTKPVIIICHGAMSWRNQMILANLSAELLRCLDAHILRFDFTGNGHSKGEWSMGNFNREYEDLLTVIDFVTNSIGCQVRCVIGHSKGSASILNCASHVAKQELEDGKDVTCKCFVNLAGRYRDPEIHNPLSKFGEEQRAEMMKKGFFEITSAWGDGRIFKVTKEDLDAYKLQSVADTPKVLVHLRKDNSIRVLTVHGHQDEVVSVQNAFRFDEEIANHSLHVIKQANHNFNGIKYLDEMVEQIVTFYKSVYNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YI60</accession>
    <name>A0AAD8YI60_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Choline transporter-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_003656</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Choline transporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the CTL (choline transporter-like) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YI60"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007603">
        <property type="entry name" value="Choline_transptr-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385:SF4">
        <property type="entry name" value="PROTEIN PNS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04515">
        <property type="entry name" value="Choline_transpo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="306"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="398"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="438"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="473"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1745732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="536" mass="57761" checksum="CD0217AE992FAE0C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJD0</accession>
    <name>A0AAD8YJD0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transglutaminase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002422</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJD0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.620.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35532:SF5">
        <property type="entry name" value="CARBOHYDRATE-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35532">
        <property type="entry name" value="SIMILAR TO POLYHYDROXYALKANOATE DEPOLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="Transglutaminase-like" evidence="2">
        <location>
            <begin position="238"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="383" mass="42691" checksum="CFA4C053EE205977" modified="2024-05-29" version="1">MDPEENYDLTESLVGGDNDAYPADISMGSNNRNTSPTTRCSGRIRSLPTLFFIVTPMIIFIIVVFLSAALIPTDVTSNSSKQATSLRDSMMQYLARHIMPYDVPNIASLGFQSNGQPKPDGMSDGIVDQTVYYSIQAKTLYPWTDSIPHYVYFEYVVPYAVTNEPRTNHRPLLFNALKDSLKQYERAAIGNSTQSTQDQIKEVVKLINTELWALMGRDSKPIVFKASQTPRIYDPLSVIAYGYSSCTGLAIMLVSALRSVGIPARMAGTPAWYGDPSKGDHSWVEVYVVSNETGKDGEWMFLEPTPGIAEGKEDTANADNLDRDPCKRWFCKADRFNGSTKTYATRYDKQATSFFPMAWADDDRGVPGEDRSKFYTSTCGKCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJP4</accession>
    <name>A0AAD8YJP4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF2358 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001310</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJP4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018790">
        <property type="entry name" value="DUF2358"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34123">
        <property type="entry name" value="OS04G0578200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34123:SF1">
        <property type="entry name" value="OS04G0578200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10184">
        <property type="entry name" value="DUF2358"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042296395" evidence="2">
        <location>
            <begin position="25"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="249" mass="28089" checksum="43CDD9C6085ACB60" modified="2024-05-29" version="1">MKMNATTTLLLYLIVATVLPCCHSFAPPTLTTTRQTLLSPLTAKDAPTDDEQEVDYRKEVVINSKNPLELASWYAVEAFGKAFGSKKESDSTTSSSDIDLNKPPSSLDETLKRIQLDNDRSYFLSGEVDRYIYDEQCTFADPFVSFDGRDRFIDNLANLGSFITNYDAKMINYNVEKNGEEVVTKVMVKLELNLPWKPVLAWPWGVTYSISPDTYLVTDHIESWDVSASEGVKQIFRPPTVKIRSKSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKG7</accession>
    <name>A0AAD8YKG7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6824 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002094</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKG7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049227">
        <property type="entry name" value="DUF6824"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20710">
        <property type="entry name" value="DUF6824"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6824" evidence="2">
        <location>
            <begin position="7"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="196" mass="21670" checksum="137C2887EB20279E" modified="2024-05-29" version="1">MEAQQNDVLSGRGACFNFHPGNKRFRSILVAQMAAYTTGTKKQKVMISKSIVETIYSMEPPGRFMKKCTDTGLWRVLSQREAADKTAQAMAYVVRTSRNATKKHSSVPLVSTTSQPNPRPIPPSYANTGLEDSASSPTAHPHVPGERASDLGRRWDTNNDLSSAADLMGRHHEFFPAGTQAMNQAMYCNEFIFKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKH1</accession>
    <name>A0AAD8YKH1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKH1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042032818" evidence="2">
        <location>
            <begin position="23"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="215"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="238"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="269"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="301" mass="32406" checksum="84AA77AFED15DAA1" modified="2024-05-29" version="1">MKLISATSILLISSYASGVANAALPPGYQEFMHCPPGSCSLYIEHDKGFAGPASAYYKCYDETTEKTTEAVWTGQYTEIEAPEGWIQDPGECEPPMSDPTTSLNIDKPGGLCTKIAIATLQSDMQHLWTPLGPDCVTVMLHHGDSPLTRLRAKQMLSWRCVIQVHVIDLKPTVLLHRMMASSFSIWQSVHCAQSILHLLLLEDSPRSRPKKHTRSTTSSSTSTSSDAPPSISKKRNGSTTTSSSTSTSSDESPPSNPIKKKRRPAYLLSATSTSATSDDSSTGIVSPTPAPAPPVQAVAEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLE3</accession>
    <name>A0AAD8YLE3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_001453</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLE3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990130">
        <property type="term" value="C:GATOR1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904262">
        <property type="term" value="P:negative regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010508">
        <property type="term" value="P:positive regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038202">
        <property type="term" value="P:TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005365">
        <property type="entry name" value="Npr3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13153">
        <property type="entry name" value="CGTHBA PROTEIN -14 GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13153:SF5">
        <property type="entry name" value="GATOR COMPLEX PROTEIN NPRL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="241" mass="26519" checksum="066C67826FEB4F6B" modified="2024-05-29" version="1">MEEAGKGARLVFRYPSAPAPIFFNQSNGDVDESKTVPPTVLQTKRGDKSCVKALSAKETSCGQPLTLNVSGTTFCCRAELFDSQPSTVGGDGSNHPLVLFSVIVALAPLASSDGAAAPATQFDRANPADNTTNAAPQKRSDFAFSAIRRVHDNLASLCRVLKREELRCRYVSRQCSMLLQVRKEFEAREGPDDDRRGNEGVEQVVNLEWMEVLLTMTCPLLRRIKGRYPLLLSNQSKQRDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLI2</accession>
    <name>A0AAD8YLI2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLI2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="124"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="190" mass="22053" checksum="9169B1CBBDCBADE9" modified="2024-05-29" version="1">MDNSALAVAIREQLIAELSKSAKVTTSIGVVTDDCNKENNIVREGILLELTKPNNPSLRNVKDASIQTDTEESAANNHAGNDTKIEQKMMEIEHECEQRLRREFNGKLRLSAKQQAMQAHTRLERKHKDECRSLQKQLAEERSRSKHREKELLQAISQQQMSWQKELKEVEQKLEKSMLEKSTLRVRWDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLV2</accession>
    <name>A0AAD8YLV2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA-directed RNA polymerase I subunit RPA49</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_000717</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLV2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009668">
        <property type="entry name" value="RNA_pol-assoc_fac_A49-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14440">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06870">
        <property type="entry name" value="RNA_pol_I_A49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1748778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="464" mass="50995" checksum="1CB23722749BAFA5" modified="2024-05-29" version="1">MSSSSSSSSSSSGSDDDSVQSASVGEKRKMDTSSSSTSKPSSASIKVKVAANNPEYDPLLYHSTRNPTSIADEDSNATPPTFTYSKFKESSSRGRRIKGEDDHCAYSAAASGRGHDGRLSKTYVCIFDKKKNTLKLVPSAEKGTVFALDQSVKEYSPAVANENSTMGGEDNTISASDRVKMLVDSFGSKKKQKVMDSRAANKVNVHSVVGGGNFVPENVKDSAANVDSQEVSYEQARRDFLPPFDADADAPQKVYNAQALMGEAAWNKVSGIVNRRLRDLKEQGGDSGETICEMLVGKGHCPKSIKVLMRDIKPSATGSPYRFKVAFFLYLIMRFYNKIDRRGFLRGKTVDDCINECTFHMRLESEFLIVHHPIEGKEDGFLLSKQLKTKMYVYCLILFIIASSKDMAVPDITPLYKDLRLDDKQAAMILREAGFLVKKSKKGEIGVTLSTPLVFPPPRRGKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YM87</accession>
    <name>A0AAD8YM87_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YM87"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="118" mass="13098" checksum="98B7B13E25010C7C" modified="2024-05-29" version="1">MTIHSRGQLTTTTTTTNDGSGGKRKRVSRKAKELELMMLLIMLLLPRYGGLGEFGRKGYCTGRYEKVVGNGIRPALGEFKEQLTDALREEGAIAKKEEEGALLGFLRTGYNLYAIRNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMW0</accession>
    <name>A0AAD8YMW0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Kinesin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_000179</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMW0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF75">
        <property type="entry name" value="CENTROMERE-ASSOCIATED PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 3" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="6">
        <location>
            <begin position="28"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="139"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="239"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="690"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="735"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="929"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1005"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="542"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="866"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="144"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="239"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="694"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="940"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="954"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1021"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1053"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1107"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="135"/>
            <end position="142"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1748240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1117" mass="122545" checksum="887D955F9A1896AD" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YN10</accession>
    <name>A0AAD8YN10_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">2-dehydropantoate 2-reductase</fullName>
            <ecNumber evidence="6">1.1.1.169</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_000176</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ketopantoate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.169" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YN10"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008677">
        <property type="term" value="F:2-dehydropantoate 2-reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050838">
        <property type="entry name" value="Ketopantoate_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43765:SF2">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43765">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketopantoate reductase N-terminal" evidence="4">
        <location>
            <begin position="39"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Ketopantoate reductase C-terminal" evidence="5">
        <location>
            <begin position="239"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1748237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="382" mass="42577" checksum="7D957EBB517B29A1" modified="2024-05-29" version="1">MTTCSMIRPHHLINLCCKNTKTKLMSTSCVQRDLIFPMHTLGGGSIGLLFAAALQKSCGDVTMLLRKHHKPRLSITSCEKSSTATNYFAPVQVCRPSDRQIITTCDIRAEIIGDVHDPIECLLICTKANDAITALSSIWDRLDRKNAAKVIILSNGALAIRDSIQRHFNDHQDLQIITATTTHGAYTEQSSDTKSNISGYCVVHAGEGLTYCTNDKFIDACEKVGWKGGALSEFEMNMMLWRKLAANCVINPLTAIHGVKNGQLLSLDNTDRTITCILEELSSIAILEMESFIQAEEDVEVQAHLQRSIRAELSVDFLKNFVTKVMTDTADNISSMLQDVNAKRTTEVRFLNGYVAHLGKEKYSIDCQYNKDMCNRVEDLKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YN79</accession>
    <name>A0AAD8YN79_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000329</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YN79"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040632">
        <property type="entry name" value="Sulfotransfer_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978:SF4">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17784">
        <property type="entry name" value="Sulfotransfer_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="404"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="404"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="442" mass="51078" checksum="0F1CDBC92F3342DE" modified="2024-05-29" version="1">MYSGFLLIVVATGWLFSRKAKITENTNQASPLRHTNIRMVIVSAISFFLGLQFSHLTALFQIDFSAGGLIDSHATEYMTWAPDEIEQAQRRNRGTRRRRKPNQSNAHKRKKKKNKPPPRYHDSNYTKESFEPLPWSLPKPSSTRYQTSEEFMADYIALKRKHNIPLPWEQDKYKEDKVTLPRPIIGLNFPKSATLTMSEYFACGGITSTHTTTQDGRIGICMMENQLKDKPPMEGCNAHRNRKKEETKPIEVIFDIGLQGPPCYYASLHDGGLENIAKHYPEGTIMLVTRNATKWFNSFEGWGGILKAWGQRSCGFDGSLEGEGMEYWNDLYMSNRSKRKYWLDFYEAHTQKIREFALKHLSLTYVEVELENDKMAEQLELYTGVKQSCVQVCHPGPHWIRKHDTTSKCHPKGEEPPSIDTEEANEYSDDEDNTFVEFNRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YNS2</accession>
    <name>A0AAD8YNS2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">D-lactate dehydrogenase-related protein</fullName>
            <ecNumber evidence="5">1.1.1.28</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_000689</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.28" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YNS2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008720">
        <property type="term" value="F:D-lactate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058205">
        <property type="entry name" value="D-LDH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43026">
        <property type="entry name" value="2-HYDROXYACID DEHYDROGENASE HOMOLOG 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43026:SF1">
        <property type="entry name" value="2-HYDROXYACID DEHYDROGENASE HOMOLOG 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="4">
        <location>
            <begin position="202"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1748750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="348" mass="38274" checksum="D13D884D5F5A0A70" modified="2024-05-29" version="1">MAKLALDNAEWLSTLSEPLKNDIESIMTQRLPSEGDCLLKEAGAGNVTGFLHVVGHHDDDMAFANVIAGKDAKVWIVRGEEFRAITENPQHTTEMMNLLTRLLRKASKIVRATLNETGVRVGRSSEGTGRTIKIMCYDTTSWNFEPQIEKFNNEGKDLKLQMDYTSDRLDVKTAKYAAGYDAVCLFVTTIRIHPHCGYYPWPDSGLLGMDIHGKTVAVMGTGKIGQILCKIISGFGVNLLAYDVFESDEVKNLGGTYVSKEEIYKQADVIFLMMPLLPATTHTINEDVLPMLKKGVILINTSRGGLIDTNALISGLHSGIIGGCGLDVKMKENTSFRITAPKALRMSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPQ8</accession>
    <name>A0AAD8YPQ8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transmembrane transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_001076</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC35F solute transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPQ8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009262">
        <property type="entry name" value="SLC35_F1/F2/F6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052221">
        <property type="entry name" value="SLC35F_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14233">
        <property type="entry name" value="DUF914-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14233:SF4">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER F2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06027">
        <property type="entry name" value="SLC35F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="80"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="426"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="436"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1749137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="472" mass="52291" checksum="3D3D816DB99A205C" modified="2024-05-29" version="1">MVHCPCPRRRNVRRSSGDSASLVQSISQTVTSTIVDGLVHTASHWRVILLGQGVALVLAVAGAANEILSMECTVSAPSTYNFFTYSIIAIFGAFALKREEKLSKADEINIEEQERFQSIGPSGQGDGDVEDDEITIDSEPRQTRFSIRRSQRDTTTIRSGNNSTGSKDKIRTYPFLCGLFTIHAKWYYYAFVALVESQAYYLIFVAFRYTSFTFVYVSDALAIPSAMIFTKLIMKRGYLWMHLIGGAICVAGIVMNTAGDMTLQDGLEHAASFEHIRGDLYAVLGAVLLGLDDVLSEILVTNFGGVREMLFMKGLFGALISILQICFFEIDNVRDLFGSNYGAPCDMSRRMVLFFTHIAFRALDVWGEMQFLLVSEAALLNLMLLTSDLYAALFDVIRVGLHLTGYFYAAFGTICFGIVLYEAGPSPTESGNSETTPKDIEFHSREEDESFVADTEHTSNLGNKIRTHGELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPY8</accession>
    <name>A0AAD8YPY8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_001196</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPY8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045900">
        <property type="term" value="P:negative regulation of translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000183">
        <property type="entry name" value="ABC transporter ATP-binding protein yjjK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000011">
        <property type="entry name" value="Putative ABC transporter ATP-binding component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00847">
        <property type="entry name" value="EttA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022374">
        <property type="entry name" value="EttA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03719">
        <property type="entry name" value="ABC_ABC_ChvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008775">
        <property type="entry name" value="PRK11819.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43858:SF1">
        <property type="entry name" value="ABC TRANSPORTER-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43858">
        <property type="entry name" value="ENERGY-DEPENDENT TRANSLATIONAL THROTTLE PROTEIN ETTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="9" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="119"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="441"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="74"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="672"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1749257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="672" mass="73858" checksum="A8D3B564CE0E1EE4" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4Y0</accession>
    <name>A0AAD9D4Y0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014983</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000040">
        <property type="protein sequence ID" value="KAK1734216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4Y0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="495" mass="55471" checksum="6A49DB84B318404F" modified="2024-05-29" version="1">MDGIFCANFLASRDGWPRCQQAWHAECYTCLGQGKFPLEELVDEEGNVWHTQEEREKRVNFGVKGAHLVVPFQCEICWLRQLEKRDPTSSDSDYIMYIRRVNLDAIAGRSKKTISAHNNKMARIIGNCKALGKTPSYPPRGPFPNEDCVGMGVAVDMQYESVHAVGRIRDHIQFSSLRHVRSTYTVSYQSSAGGLQEGAAFSKGKGMVRPTRCPTQSQFFIDFLRGCEYRMGSESRANQPISIRATVEILRRIRMMAADETESDLALSNYYYRVGAMLAVLTAGSLRGYEGFYVCLAGLRKHLRSGKNGVVPADYNFHTLFSEDDARKLPHVVITLLGAFKAENGSDYHMINVANVTTSGLQVRWWVEKLVSVCESEGRFRGPAFAGPDGKLESSLDYDATFREVAKEVQGDTDTEWIPSDLDVDGCLGLSRTPRKTAETRAKQAGVSTQIQDAMNRWRTVEGSKGKTVRWKATRDTYTSAVGEMPNTWRYSHAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7J0</accession>
    <name>A0AAD9D7J0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mitochondrial carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_012317</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7J0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="20"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="167"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="291"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="137"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="204"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="351"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="354"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1736872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="479" mass="52563" checksum="3C6A7BFDA7692121" modified="2024-05-29" version="1">MSNHQSNNNNSALATIQSLPKAARNLIAGGLAGMIAKSFVAPIDRIKILYQVTSAKFRLRDVPKVAYSIIEKEGWSALWKGNTATMIRVFPYSGIQFMVFDYCKTIFLLRDKKEHQQLKATAATTTYADVAGKRHNDTLQNHGTIDNPHSNTTTTAQHHDNSSKGGLSPIDSLISGMAAGSISVLCTYPLDLARAQLAVLRKKKKPKDVLSAPSPTKSKTNIDKLGIGSTSQSSRKGIGYVLSSGFQQRGLRGLYRGITPTVLGILPYSGTAFTINEQAKLKITRIMHREPTTIERLQCGALSGLFAQTLTYPLEVTRRRMQTIGIVPTSGSESAAVNFTGVSQLKPSVDELPAEQQQQRPQAELTSQQQKPITSSQTTTTATANATTSSQQKSTVKPPSMMKTMSNLLEEQGLRGFFKGVSMNWVKGPIAFSISFTAFDTIQGWIETESEKEKKRFTGVQRRMTNKMERRITNHEDGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D800</accession>
    <name>A0AAD9D800_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA-directed primase/polymerase protein</fullName>
            <ecNumber evidence="3">2.7.7.102</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_013229</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:22509"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ssDNA + n NTP = ssDNA/pppN(pN)n-1 hybrid + (n-1) diphosphate.</text>
            <dbReference type="EC" id="2.7.7.102"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.102" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D800"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006264">
        <property type="term" value="P:mitochondrial DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009411">
        <property type="term" value="P:response to UV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044917">
        <property type="entry name" value="PRIMPOL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31399">
        <property type="entry name" value="DNA-DIRECTED PRIMASE / POLYMERASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31399:SF0">
        <property type="entry name" value="DNA-DIRECTED PRIMASE_POLYMERASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03121">
        <property type="entry name" value="Herpes_UL52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="85"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="754"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="10"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00026139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00044677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1736093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="801" mass="90747" checksum="FFD68D6415455DCD" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D865</accession>
    <name>A0AAD9D865_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011618</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D865"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="293" mass="32977" checksum="D21BE49E45F9BA48" modified="2024-05-29" version="1">MTEELKKNNNEQHRDATTRIRMNSANFHRSHSTPPNQTTPINPQNNDENNAIRNNNNETASAVILLGISTGAARLSAYNRSTSDSRDGLREGLQISSTFNNLDDAPVSLLYDDCYDDYYDDSDKENIDPLQTKVIKARCPARPMCTFHESDDDDEEDGFVQVLMPLGQKKKKVQLNNKSGGVSNHASITVNNGQDDVLVEKKCNRLDNVKRRGDPRHGTINSKKKNHSMIKSTKKNDDLMSKTSATSSNVSRTKKMSASHNKKMTSNDLQQEVDKALQPLMNSLSLRERRFNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D868</accession>
    <name>A0AAD9D868_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alcohol dehydrogenase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_011908</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D868"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050700">
        <property type="entry name" value="YIM1/Zinc_Alcohol_DH_Fams"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695:SF294">
        <property type="entry name" value="RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11969">
        <property type="entry name" value="DcpS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00332">
        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="3">
        <location>
            <begin position="54"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="2">
        <location>
            <begin position="163"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1737622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="558" mass="61950" checksum="1E2347341A404A4E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8P8</accession>
    <name>A0AAD9D8P8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cobyrinate a,c-diamide synthase</fullName>
            <ecNumber evidence="7">6.3.5.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_012379</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.12" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8P8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042242">
        <property type="term" value="F:cobyrinic acid a,c-diamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004484">
        <property type="entry name" value="CbiA/CobB_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011698">
        <property type="entry name" value="GATase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011124">
        <property type="entry name" value="Znf_CW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43873">
        <property type="entry name" value="COBYRINATE A,C-DIAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43873:SF1">
        <property type="entry name" value="COBYRINATE A,C-DIAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07685">
        <property type="entry name" value="GATase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07496">
        <property type="entry name" value="zf-CW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51274">
        <property type="entry name" value="GATASE_COBBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51050">
        <property type="entry name" value="ZF_CW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="7" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CW-type" evidence="6">
        <location>
            <begin position="616"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="domain" description="CW-type" evidence="6">
        <location>
            <begin position="713"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="278"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="332"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="530"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="222"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="278"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="297"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="348"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="391"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="418"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="542"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1736934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="785" mass="84982" checksum="7AF415D71A082D18" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9D6</accession>
    <name>A0AAD9D9D6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011804</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9D6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="42"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="338" mass="35573" checksum="BCE36FE9A17E31D7" modified="2024-05-29" version="1">MLSSTFTRAALTSQRQQKVYARARFLSTVEVESKGFSSKSRDETVDPMEVFDSIDTNGDGVLSKEEFQQAVEKMHYSDLLKIKNSLSRNELSYNPSADKEMSLSETHASVIGRRMTVTAEVAISKIFPAGFGWQTAAYFAENAGMEATDLSFFLSTGLGDGIGVCAGHTLYCAGKKAVTGNADISLGKELQVGIMLGSAAVCSGGVWQPTVNALQAAGWGFTNSMIATGGVATLAFFTGLRLGRLVYAPIFEGVEEATYANLKADAALSVAVGGAAGCFLGTDLSYGAANYLGDAIGIQESFSPLVSSAMAGTSTMLGFGVIQSGENLVYAKDKCWVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9Q0</accession>
    <name>A0AAD9D9Q0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011202</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9Q0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="321" mass="37119" checksum="FD0E77D59B9B169B" modified="2024-05-29" version="1">MADDGDNNVFVYMGGEQVVPHDVTHVIIDRSVKIIPERAFEHRRELVSVKFHDGVERIEKYAFRGCKSLRRLNKLAGVREVGQWAFWFCSALTEVEFDDKLEIIGSGAFRDCRSLRKIKVPSVRTIEYGAFADCVALTDVELPDVERIEFFAFHNCPNLRRIAIPLRDNMFAPDRYQRYTHFHYCRNLTTVDLVGGIRNTVTSLLLQRWTDDMNSEIDRINQVLPNTDVNEKTAVIDQWIRTVLRRMDHYKAEHNKLLKEATTLLELAIWKAKLDEKEDCSIEGRAKKAKIDTAGARINRRITSGANIVIRNVLPFLQLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9R3</accession>
    <name>A0AAD9D9R3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit</fullName>
            <ecNumber evidence="7">2.4.1.255</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_011247</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.255" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9R3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097363">
        <property type="term" value="F:protein O-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037919">
        <property type="entry name" value="OGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029489">
        <property type="entry name" value="OGT/SEC/SPY_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44366">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44366:SF1">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13844">
        <property type="entry name" value="Glyco_transf_41"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-GlcNAc transferase C-terminal" evidence="6">
        <location>
            <begin position="476"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="O-GlcNAc transferase C-terminal" evidence="6">
        <location>
            <begin position="693"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="188"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="916"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="197"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1737953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="946" mass="107744" checksum="66D6E8E92F90B7A4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAX7</accession>
    <name>A0AAD9DAX7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Carboxypeptidase</fullName>
            <ecNumber evidence="10">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_008896</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Preferential release of a C-terminal arginine or lysine residue.</text>
            <dbReference type="EC" id="3.4.16.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
            <location evidence="2">trans-Golgi network membrane</location>
            <topology evidence="2">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="10"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAX7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033124">
        <property type="entry name" value="Ser_caboxypep_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF190">
        <property type="entry name" value="PHEROMONE-PROCESSING CARBOXYPEPTIDASE KEX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00560">
        <property type="entry name" value="CARBOXYPEPT_SER_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="10 12" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0732">Signal</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041782380" description="Carboxypeptidase" evidence="10">
        <location>
            <begin position="19"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="547"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1740801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="588" mass="65540" checksum="4E8B7C3AD5021009" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBA3</accession>
    <name>A0AAD9DBA3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008279</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBA3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="1">
        <location>
            <begin position="202"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="790" mass="87853" checksum="997B3069E510118D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DC60</accession>
    <name>A0AAD9DC60_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ubiquitin-like-specific protease</fullName>
            <ecNumber evidence="7">3.4.22.68</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_006701</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.22.68" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DC60"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016929">
        <property type="term" value="F:deSUMOylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016926">
        <property type="term" value="P:protein desumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12606">
        <property type="entry name" value="SENTRIN/SUMO-SPECIFIC PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12606:SF1">
        <property type="entry name" value="UBIQUITIN-LIKE-SPECIFIC PROTEASE 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="6">
        <location>
            <begin position="477"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="69"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="154"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="302"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="421"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="77"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="302"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="316"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1742136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="692" mass="78326" checksum="CAA793F6668BF048" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DC74</accession>
    <name>A0AAD9DC74_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DC74"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="207" mass="21936" checksum="A15E4D672BC856D8" modified="2024-05-29" version="1">MGGVEEHPFGEITKRISRRKYGNRHSDGGDEELDGNDNALGNDGSVSDQCSTESKAATLTPPIGNTKSTGSSGNAESEEKLDESDAATSSETTTGTTTTADETTATANAGTKRKYPGSAESVATRSSTASSRLGRGTRRHRSSSARPYSLAIPTVSEVIVRKVLNKVRKTRNISSLRMLMSLPKGRARRSKHDDITATVVDLSGFVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCE8</accession>
    <name>A0AAD9DCE8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BAR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008720</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCE8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="445"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="187"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="407"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="456"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="481"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="520"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="536"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="577"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="586" mass="62712" checksum="42D0F1B7DE46C51E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCV8</accession>
    <name>A0AAD9DCV8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008355</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCV8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1741103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="192" mass="21363" checksum="52924F6CE6DDA7A5" modified="2024-05-29" version="1">MGISTGGGIAFYMAQRHPDKIKAAFLMHSIPLCGLRYITVTGELVPLVDLDQVKASMMFPTDDPDFVYELFKSMNHKLTEYMIKAAQDMPGKDDIAVVNTKFNVTPIKTIFGPPSDALSTLKSKVVVIHGSEDFIAPWLIVEPVTRLAIIEQWAPLGRLSLYDDGAGHTSLIDKPRVFAKVYRRALEEQILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DD41</accession>
    <name>A0AAD9DD41_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_007836</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DD41"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1741358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="83" mass="8963" checksum="5EFFBF7107CA7ABE" modified="2024-05-29" version="1">MKKNITRIFAVALHFQVASSLDKRLETHFEGTLHADGSIFEVVSKGQQVSITSFDVNMDTGTDTVSVYSRPGNLVASDDGNGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DD67</accession>
    <name>A0AAD9DD67_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Heat shock protein 90 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_006589</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DD67"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16927">
        <property type="entry name" value="HATPase_Hsp90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.790:FF:000001">
        <property type="entry name" value="Heat shock protein 90 alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.80:FF:000001">
        <property type="entry name" value="Heat shock protein 90 alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11260:FF:000001">
        <property type="entry name" value="Heat shock protein 90 alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000001">
        <property type="entry name" value="Heat shock protein HSP 90-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="entry name" value="Heat shock protein 90, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00505">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019805">
        <property type="entry name" value="Heat_shock_protein_90_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003555">
        <property type="entry name" value="PRK05218.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110942">
        <property type="entry name" value="HSP90 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00298">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Histidine kinase/HSP90-like ATPase" evidence="9">
        <location>
            <begin position="29"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="215"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="677"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="219"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="102"/>
            <end position="103"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="122"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="378"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR002583-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1742992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="708" mass="80371" checksum="B6F2A0AB38CA47CF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DE42</accession>
    <name>A0AAD9DE42_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006336</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DE42"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31630:SF8">
        <property type="entry name" value="JMJC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31630">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="459" mass="52299" checksum="A0039E7AE153E6C0" modified="2024-05-29" version="1">MHLFHNCWCFVRDLLEWCDFCMVRFLKAGSLLMLTIHLCGYAILCYAAVCCCSSRQPTMSDPHLSLEQISTYLHDGILVVDNLLSPSEIIEAQTSLAQTLLNDNNVDISNLEETGHNLTNASSTNGAGGVLDIFYPDWKMSIATNEQLFRMTCQLWKESYCNGETKEDVRWHPYGTFDCNRGYMYIDRIGFRLPSKLAESIGERQLSNKEATTDATAINNASTTRKKKKKKSRAIQRSLTPHFDLCPEAYHDVTNKNKWRPIQCFVSLTDNLLPNTGGFEAAPGFHREFHSWVQNGRRLNSNSDDSAIASGEVMSSPKQQQPCIGEYTHVHDRELMKRVQHIPVRAGSVVFWDNRLPHGNSYRNDNSYDQTVPSSTAPLESCGARAVVYCSFLPDIAINRRFVERQLIDWKLGRAPRVGDRWIKQDGEEEDDDDNDLRNNEMELQLSDLGRKLIGLDKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEB2</accession>
    <name>A0AAD9DEB2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">G protein-coupled receptor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_005639</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEB2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="13"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="295"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="355"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1744042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="421" mass="47691" checksum="43AB7C6773BEFE8A" modified="2024-05-29" version="1">MGWTAEQSKILSIIPHFTGAFSFIGSSSIITMILRDRRKNLSKPYYRLLFAMCVFDIFASVALGLSTWPIPEGSPGVYDPKGTVGTCSAQAFFIQANIASPVYNFMLSVYFLLRVKYGMNENQIGRRAEPIMHVITVIFGLGTSFLCLGLSLFNDSTLWCWVNASPKGCDQSYANNGETDCERGDNAEIYRWAIFFGPLWACIIGCMVIMIIIFMSVRKQENKLKKYQFKPRRESESSNAGDEEFERKKKEEERRRHAQSRQVAWQGLRFVGVFYLTWAFATVNRLLQLINGGSYFWLMCLHTIFVPMQGFFNFLVYIYPRFKARKRAGVRSHHVGATIRRISITSQIRRWNSVEETNVESPPVLAEKSNDGGDEENGAAVAGEGSKVEETWEENEAVTLPVKSVSLMKGSFDGETTHMST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFB1</accession>
    <name>A0AAD9DFB1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Polyamine aminopropyltransferase</fullName>
            <ecNumber evidence="14">2.5.1.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_006169</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.16" evidence="14"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFB1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004014">
        <property type="term" value="F:adenosylmethionine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004766">
        <property type="term" value="F:spermidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.90.10:FF:000025">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.90.10">
        <property type="entry name" value="S-adenosylmethionine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00198">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003826">
        <property type="entry name" value="AdoMetDC_fam_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030373">
        <property type="entry name" value="PABS_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016067">
        <property type="entry name" value="S-AdoMet_deCO2ase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001045">
        <property type="entry name" value="Spermi_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558:SF11">
        <property type="entry name" value="SPERMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558">
        <property type="entry name" value="SPERMIDINE/SPERMINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02675">
        <property type="entry name" value="AdoMet_dc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01564">
        <property type="entry name" value="Spermine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56276">
        <property type="entry name" value="S-adenosylmethionine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01330">
        <property type="entry name" value="PABS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="4" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 11" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0704">Schiff base</keyword>
    <keyword evidence="3 11 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="PABS" evidence="13">
        <location>
            <begin position="215"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1743548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="622" mass="70137" checksum="6C99D4BA03AE4DD5" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFQ2</accession>
    <name>A0AAD9DFQ2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002643</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFQ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="172" mass="19635" checksum="3D6A069986CC5B23" modified="2024-05-29" version="1">MNPDDSFDADDEIQRHINEATEISRNNVNSWNNVSNPEAAGREKVIKTQLHSEIRAELCRLQGVHQSLYSEIDPLHMPEVLSLIGRHHDQGDLYLALKSSIMTLFSTVNMKKCIQQQRAYHAAIVAKHAAIVAEHRTKMEELDAKLTSMDEAVEVNEGSNELEHRSNKRRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG87</accession>
    <name>A0AAD9DG87_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005026</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DG87"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="100" mass="11242" checksum="A7FC9D76889B6F0C" modified="2024-05-29" version="1">MMVPSSPAASSSSASSNSPVSPDNLTVQLLARLDTQSYTNALTADAASLSHHFLLPHDFPWARFRRYYDKDVPPSRETFVEKELPFDIDELDAICYYSDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGF0</accession>
    <name>A0AAD9DGF0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Kinesin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_003979</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGF0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24115:SF1004">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KIF15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24115">
        <property type="entry name" value="KINESIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="4">
        <location>
            <begin position="590"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="369"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="470"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="501"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="953"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1191"/>
            <end position="1225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="382"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="428"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="439"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="480"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="673"/>
            <end position="680"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1744688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1255" mass="138941" checksum="A94C810AAC2461BE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DH88</accession>
    <name>A0AAD9DH88_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Beta-catenin-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_003422</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DH88"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039678">
        <property type="entry name" value="CTNNBL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013180">
        <property type="entry name" value="CTNNBL1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14978:SF0">
        <property type="entry name" value="BETA-CATENIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14978">
        <property type="entry name" value="BETA-CATENIN-LIKE PROTEIN 1 NUCLEAR ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08216">
        <property type="entry name" value="CTNNBL"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01156">
        <property type="entry name" value="DUF1716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Beta-catenin-like protein 1 N-terminal" evidence="7">
        <location>
            <begin position="116"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="67"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="427"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="434"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1745498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="765" mass="84116" checksum="2B38DC0949C20454" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DH89</accession>
    <name>A0AAD9DH89_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001694</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DH89"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042196166" description="AB hydrolase-1 domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="82"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="361" mass="40443" checksum="3DC42DD5EFDB63D2" modified="2024-05-29" version="1">MYRLVFLLGLVLHISSTLAFLQGCNRGKSQRVVISQQATTLNYDSSKASSNKIELQRYNHKSFNLTYLYKEAAPGREKDSPIILIHPVGIGLSSWFWKRLMDSYEDNPPIYAPDLIGCGIDHGADAWDPDTIGLFFPLSWVEGIETLINEIVIPNWRESQTLQLPSMFGINRQGKESNGCLVIAQGGLAPVGIMLAKRNPLTISNLMLTSPPTYTDVTTAVPTAELQRNYEFLRSPILGSIAFNLLESRALIKFFSNSFLFQEECDDDWLDETDKESVVAARTPVQAFNAGLLQHRSFEEDLKESPQPKLIVSGEGDKRAVDRQPYEEQLDTCSLTTIPGLNVLPWESPKEVVDLIKELGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DI90</accession>
    <name>A0AAD9DI90_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Polysaccharide pyruvyl transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002433</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DI90"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="813" mass="90321" checksum="972BFCF8B047D9CC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIL6</accession>
    <name>A0AAD9DIL6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Diacylglycerol O-acyltransferase</fullName>
            <ecNumber evidence="11">2.3.1.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_002359</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the diacylglycerol acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.20" evidence="11"/>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIL6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004144">
        <property type="term" value="F:diacylglycerol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007130">
        <property type="entry name" value="DAGAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317:SF34">
        <property type="entry name" value="ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317">
        <property type="entry name" value="DIACYLGLYCEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03982">
        <property type="entry name" value="DAGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1747015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="269" mass="30457" checksum="F3E56AAFED872346" modified="2024-05-29" version="1">MTPILNTKEMKSDHLSIIAMHPHAILPLHGYIWGAICHQLLPDLYGCGAATEIAMRLPVLRHTLRYLSTRSADKKGLLQQLQIEEENLFILPGGVAEIFYSQRRRQPNSLPFTQTIKAKRYGLMKLSLQTGARIFPAFVFGASDMLDQLFHVDQNVASKEKDAKTFDIGLMMQSISRKLKGGIALYYGQYYLPIPHTPKLSMVLGDPIYPVENTSERNVNGNKLTCKRIANPTDAQVEELMDRYVNSLQCLFEQYKVEAGYPNDRLVIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIL9</accession>
    <name>A0AAD9DIL9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">STI1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIL9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042203694" description="STI1 domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="130" mass="14550" checksum="5D70E70375AC9A4C" modified="2024-05-29" version="1">MKLLSALFSTTLFAAIAFSVDAKDDAYVYGKDPKKDAEYDISMGMAGIQQAAKDPKMLAQLFQDMQDPQLMAEAKKMMESPEWKKKMKNLTNDKNFKQSAQAAAKAMEDPNEAAKLQAKMEHMMKKGTMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJU3</accession>
    <name>A0AAD9DJU3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SANT DNA-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000753</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJU3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051083">
        <property type="term" value="P:'de novo' cotranslational protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006450">
        <property type="term" value="P:regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.840">
        <property type="entry name" value="Ribosome-associated complex head domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042569">
        <property type="entry name" value="RAC_head_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044634">
        <property type="entry name" value="Zuotin/DnaJC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43999">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43999:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23082">
        <property type="entry name" value="Myb_DNA-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="193"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="272"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="331" mass="37370" checksum="7C1FE14DD8FE9A6F" modified="2024-05-29" version="1">MKKEEMARVNLLVERAMAADPRLSREKKREKLEKERQAEAKRKAEEETAEAERVAKEKQDAENAKKKTEEDAKKKNAKQLKEQQKKQLRKAKQQFRKLTMAAYQAASPNDSSDSDGVWDDMEKMNDDVELLCEKLSALELDSLSEALGGPNGLAEVREVAIETAAGSERQSLLAIEARNRARKEDADKQKEAKLAKTSAPWTKDELAALSKAIKKYPAGGAARWDAIASFINNLCKQEEPRTKEECIEKYNLIASAPAAKDTTAAPADDKAWTEKEDTLLQDMLRKYPASMEKNERWKSIAEGVPGRSKKECVERFKAIREAVRGKTKEMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DKA8</accession>
    <name>A0AAD9DKA8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zinc-finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000437</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DKA8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16449">
        <property type="entry name" value="RING-HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="250"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="378"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="548" mass="60311" checksum="1802120011546762" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DKJ0</accession>
    <name>A0AAD9DKJ0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001099</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DKJ0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042175160" evidence="1">
        <location>
            <begin position="19"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1749160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="126" mass="13717" checksum="240D703EC7F1BB18" modified="2024-05-29" version="1">MKLASFISVLATSSCTFAFTATSINTFKSRDTIVLLSTPDPNNPCWQDNYDSDDDCLSTTYSAAFVAEEWIKSLPCGKDADCLPEELTHPGTMGDAGVEKVNVMEYLNIHKAATLTAKKEKTDKAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2LM04</accession>
    <name>A0A7S2LM04_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450 family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_014525</name>
        <name evidence="10" type="ORF">SMAR0320_LOCUS13569</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="HBGZ01018909">
        <property type="protein sequence ID" value="CAD9610428.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S2LM04"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF50">
        <property type="entry name" value="BIFUNCTIONAL ALBAFLAVENONE MONOOXYGENASE_TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="462"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CAD9610428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1734652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="518" mass="59524" checksum="A0D87A45413B6956" modified="2021-06-02" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2PZ79</accession>
    <name>A0A7S2PZ79_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006373</name>
        <name evidence="1" type="ORF">SMAR0320_LOCUS20451</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="HBGZ01028762">
        <property type="protein sequence ID" value="CAD9625784.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S2PZ79"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CAD9625784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="107" mass="12231" checksum="FE764C510667A9E4" modified="2021-06-02" version="1">MSRSLGPQINSRAHIIVRDASTSGTIANKEKMISSSTGSFFDHRKDDDKNRFSMKRAQVITVLEENAFIIELKIERDYDYIDRKTFHFPCSPMAKNALKMLTSGEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-08-03" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8K1H034</accession>
    <name>A0A8K1H034_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Photosystem I reaction center subunit II</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">psaD</name>
        <name evidence="5" type="ORF">QTG54_017196</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="6"/>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2021" name="Front. Plant Sci." volume="0" first="0" last="0">
            <title>Chloroplast Genomes for Five Skeletonema Species: Comparative and Phylogenetic Analysis.</title>
            <authorList>
                <person name="Liu S."/>
                <person name="Xu Q."/>
                <person name="Liu K."/>
                <person name="Zhao Y."/>
                <person name="Chen N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CNS00100</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">PsaD can form complexes with ferredoxin and ferredoxin-oxidoreductase in photosystem I (PS I) reaction center.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Plastid</location>
            <location evidence="4">Chloroplast thylakoid membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
            <orientation evidence="4">Stromal side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the PsaD family.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000082">
        <property type="protein sequence ID" value="KAK1732153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MW679506">
        <property type="protein sequence ID" value="UAM91398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_010200909.1">
        <property type="nucleotide sequence ID" value="NC_058701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8K1H034"/>
    <dbReference type="SMR" id="A0A8K1H034"/>
    <dbReference type="GeneID" id="68638037"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009538">
        <property type="term" value="C:photosystem I reaction center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1470.10">
        <property type="entry name" value="Photosystem I PsaD, reaction center subunit II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003685">
        <property type="entry name" value="PsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036579">
        <property type="entry name" value="PsaD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31982:SF5">
        <property type="entry name" value="PHOTOSYSTEM I REACTION CENTER SUBUNIT II, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31982">
        <property type="entry name" value="PHOTOSYSTEM I REACTION CENTER SUBUNIT II-1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02531">
        <property type="entry name" value="PsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64234">
        <property type="entry name" value="Photosystem I subunit PsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="2 4" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="3 4" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0793">Thylakoid</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1732153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="UAM91398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="139" mass="15504" checksum="AFD7319C87EBC265" modified="2022-08-03" version="1">MTLNLKTPFPTFGGSTGGWLRAAEVEEKYAITWTSAKEQIFEMPTGGSAIMRNGENLLYLARKEQCLALSTQLRTFKINDYKIYRIFPSGEVQYLHPKDGVFPEKVNPGRTSVNSRGFSIGKNPNPASIKFSGITTYES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRN4</accession>
    <name>A0AAD8XRN4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_016964</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000072">
        <property type="protein sequence ID" value="KAK1732334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRN4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000400">
        <property type="entry name" value="Nuclear pore complex protein NUP107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45974:SF61">
        <property type="entry name" value="LEUCINE-RICH REPEAT (LRR) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45974">
        <property type="entry name" value="RECEPTOR-LIKE PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="915"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="983"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1042"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1077"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1148"/>
            <end position="1192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1732334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1238" mass="137901" checksum="CF7F7FE002E34721" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XS06</accession>
    <name>A0AAD8XS06_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_016983</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000073">
        <property type="protein sequence ID" value="KAK1732316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XS06"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="450"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1732316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="500" mass="55579" checksum="4EA175B8FE60A14A" modified="2024-05-29" version="1">MGKGNDLGWLGYFIGRSVKIQHLDICHFPEGRQQIDAFFDGLARNQSIRSLSSHQLGDYGSTALLRALGNLSQLEELTYSGSNLTRNGWSALGTLFESGACKLKKLWLYNNNIGDDGVAALASGLRSIGPSLNKLGLSDNSIGNEGLSALVAALANCTSLEELDLSCNDFSLAAAGLISLSDWLQSNQMDLKHLDVECCGINDEGLQALCVGAAKHCEDLQLAGNDAITASGLRYLSTSLQSESCRLENLYLGRMNIGDDGAEVLARGLIGNKSLRCLHLRDYEEDIAITRAGWSAFSAVLCDTSSVNNTYLSNHTIQELWYDCYVHDDDEDEDIPENIDEDIVLYLQLNDEHPQYAARCKILMNHTHLDMTPLLQWGLKCLPLAVGWFERSKPCTILSINEGDPNLSRRRQVLDESKEVFQSRILTALYEFVRGVPKKVLERRDELALVAAYDDKIAMVEEEKKRIQEDVESRKRKITQLEEENKRLRGVVESVRNALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSD2</accession>
    <name>A0AAD8XSD2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Papain family cysteine protease</fullName>
            <ecNumber evidence="7">3.4.22.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_016285</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.22.-" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000055">
        <property type="protein sequence ID" value="KAK1732954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSD2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02248">
        <property type="entry name" value="Peptidase_C1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025660">
        <property type="entry name" value="Pept_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013128">
        <property type="entry name" value="Peptidase_C1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000668">
        <property type="entry name" value="Peptidase_C1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039417">
        <property type="entry name" value="Peptidase_C1A_papain-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013201">
        <property type="entry name" value="Prot_inhib_I29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12411">
        <property type="entry name" value="CYSTEINE PROTEASE FAMILY C1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08246">
        <property type="entry name" value="Inhibitor_I29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00112">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00705">
        <property type="entry name" value="PAPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00848">
        <property type="entry name" value="Inhibitor_I29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00645">
        <property type="entry name" value="Pept_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00639">
        <property type="entry name" value="THIOL_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042219418" evidence="4">
        <location>
            <begin position="20"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Cathepsin propeptide inhibitor" evidence="6">
        <location>
            <begin position="36"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C1A papain C-terminal" evidence="5">
        <location>
            <begin position="154"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1732954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="391" mass="42934" checksum="FD1DB676C4C0B5DE" modified="2024-05-29" version="1">MIILRNLLILSAAAVSAAAASSSAPQAHELDESYTFDEYLSHHGKNYSGDPEEYNRRQQIFEKNLKKILAHNEGKMDESGELLNGGYVMGVNRFTDVDLEELPMGYNKNLHPDWSSQLMMHGEDDVLAVERRRLGGLESYQQSPDFEMEEVSALPQEVDWAKAGNMNPHIPQQSSCGSCWTFAATACVEAALSIATGEAPMSLSEQNLLECAPDPLQCGGTGGCEGATIELAYNFVADQTKNKKGGMFNLSDVGYQAMDETCDGLTKGKAPVVGIDGWVKLPKNDYKAVMNAVAKNGPVGLALAAGNWALYEKGVFEHTDTEVNHAVVLVGYGVDKKTKEKYWKIRNSWGLNFGEQGYIRVKRSDDDDTNCGMDNKPLVGWLALWMIMARN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XT45</accession>
    <name>A0AAD8XT45_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="10">3.6.4.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_016424</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="10"/>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XT45"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12938">
        <property type="entry name" value="GUCT_Hera"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059027">
        <property type="entry name" value="DD_DDX21-DDX50"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26142">
        <property type="entry name" value="DD_DDX21-DDX50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="9">
        <location>
            <begin position="167"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="198"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="468"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="778"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="167"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="781"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="820"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="859"/>
            <end position="871"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1732886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="871" mass="93189" checksum="E4512382C222823B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTG5</accession>
    <name>A0AAD8XTG5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Lysosomal cystine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_016204</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000054">
        <property type="protein sequence ID" value="KAK1733066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTG5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015184">
        <property type="term" value="F:L-cystine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005282">
        <property type="entry name" value="LC_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13131">
        <property type="entry name" value="CYSTINOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13131:SF5">
        <property type="entry name" value="CYSTINOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="283"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="395"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="423"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="453"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="495"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="350"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1733066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="555" mass="62120" checksum="FE8BDB7F61ACEA58" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTT8</accession>
    <name>A0AAD8XTT8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015914</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000050">
        <property type="protein sequence ID" value="KAK1733355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTT8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="105" mass="11810" checksum="1340430C7847D8A0" modified="2024-05-29" version="1" fragment="single">MIYLYMGDGHAIPRNATRIRVHESVIAIPPHAFEQYPHLVELICHDGVKTIGYRALYFCPSLKLVQIPGVIEIMAEAFAGCPLTHVTFGDKLERIRKAAFRSCKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTU7</accession>
    <name>A0AAD8XTU7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016017</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000051">
        <property type="protein sequence ID" value="KAK1733300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTU7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="78" mass="8702" checksum="6BC8B451464777D7" modified="2024-05-29" version="1">MTINYIGLVILIIGGLFLLMAIAQPKNFIVYKGLIARSEVCWGEGNGPKVMAAYSLMMIVFGLLLMFRVFGNQEEKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUY5</accession>
    <name>A0AAD8XUY5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_014856</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUY5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1734349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="619" mass="69112" checksum="659E63C7EB83D46E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV15</accession>
    <name>A0AAD8XV15_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">SAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_015122</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the replication factor A protein 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV15"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051260">
        <property type="term" value="P:protein homooligomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04477">
        <property type="entry name" value="RPA1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007199">
        <property type="entry name" value="Rep_factor-A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014892">
        <property type="entry name" value="RPA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003131">
        <property type="entry name" value="T1-type_BTB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14499:SF136">
        <property type="entry name" value="GH08630P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14499">
        <property type="entry name" value="POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02214">
        <property type="entry name" value="BTB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04057">
        <property type="entry name" value="Rep-A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08784">
        <property type="entry name" value="RPA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="3">
        <location>
            <begin position="218"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="SAM" evidence="4">
        <location>
            <begin position="430"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="158"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1734119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="589" mass="65607" checksum="2C0CEE2B7E1AB0B2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV81</accession>
    <name>A0AAD8XV81_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_015070</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000040">
        <property type="protein sequence ID" value="KAK1734303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015630">
        <property type="term" value="C:microtubule cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051483">
        <property type="entry name" value="MAP7_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15073">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15073:SF1">
        <property type="entry name" value="RETICULOCYTE-BINDING PROTEIN HOMOLOG 2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="913"/>
            <end position="1213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="115"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="237"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="292"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="531"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1239"/>
            <end position="1334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1692"/>
            <end position="1752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="32"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="144"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="163"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="237"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="321"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="334"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="453"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1242"/>
            <end position="1253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1268"/>
            <end position="1288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1293"/>
            <end position="1310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1311"/>
            <end position="1334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1715"/>
            <end position="1751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1734303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1831" mass="201562" checksum="6081F65732B1AD1B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW23</accession>
    <name>A0AAD8XW23_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Gamma-secretase subunit Aph-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_014748</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the APH-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000038">
        <property type="protein sequence ID" value="KAK1734500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XW23"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007219">
        <property type="term" value="P:Notch signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009294">
        <property type="entry name" value="Aph-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12889">
        <property type="entry name" value="GAMMA-SECRETASE SUBUNIT APH-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06105">
        <property type="entry name" value="Aph-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0914">Notch signaling pathway</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="253"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="289"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="317"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1734500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="366" mass="38962" checksum="875E2F487277F9C5" modified="2024-05-29" version="1">MTAPSLTIGTALLAFSPTLTLFFLIILPKPQLTILSVVAAFAYLLSAFGSSLIWLILNAIFQFSTNNNDDGSNSSSSIGALLALTVPSVLIQCIVRMQFVKLYFSVEDVIRKSVAKHEAETTQANNNNNNSTQEEHAETNALQLQLNDLSCSLASGTGYALLHTLFLFGTLLASESHEGSNYYGNINSASGYYGGGGGSTGHGGTLYQYSCGGVMPSLMNGALVGMMFSVLDVFWMMLTFFGMRRRLRSSRRGGVAIVGGCGGGMLSFLREMTSFWKGIDDSTQGGNAALGLVIVSHLLASLVLAPNGTMEDGCKIALPSLAGVVVLVAVLFFRGVKGHFLPMDQRARIEELRLGEGGMMGSHHVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWJ0</accession>
    <name>A0AAD8XWJ0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014499</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWJ0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042026220" evidence="2">
        <location>
            <begin position="25"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="141"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="293" mass="32720" checksum="3B3A26788FECBA15" modified="2024-05-29" version="1">MNLASFSAALAALTCGSMTSSTHAFVAPTRSYQQTTKSQQLQQKQVLFGIMDEVNSDAFDLTSLLQNDDEPSNTEMEQAYEMFLGQLVFSTNDPRIDIMENYDLCADPKWISWLENKIGSTRDVEEKMALKDLSDMIIDVKKRVELSQAKEEREAQEAEEAEKNRIAAAEGEMETGRAMSGTDVLRKAAAVDNAGVDNMVKEQEGEQKKKTFYETDLTPEIRASYEDMCSKVLPPYRPGDSAESVVFNSYDQFDAQFIKVLNERAENGDTGSQEVLAALAMEQQKRVNAAQKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWJ4</accession>
    <name>A0AAD8XWJ4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chitin-binding type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_014344</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWJ4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47849">
        <property type="entry name" value="CHITIN-BINDING LECTIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47849:SF8">
        <property type="entry name" value="LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chitin-binding type-1" evidence="3">
        <location>
            <begin position="518"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="3">
        <location>
            <begin position="733"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="193"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="278"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="362"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="460"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="558"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="680"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="833"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="199"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="280"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="297"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="362"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="471"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="487"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="558"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="569"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="712"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="861"/>
            <end position="871"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1734884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="917" mass="100245" checksum="2CD446706F4940CE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWN6</accession>
    <name>A0AAD8XWN6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014119</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWN6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="72" mass="7701" checksum="F31C0FF9AA08F8B4" modified="2024-05-29" version="1">MMEDSSLPDIETAGGAEAQQLEQRQKPSRKYATITVGVALGALIAIGVVIGTSSPMEGLRWRSSCIPNARRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWT0</accession>
    <name>A0AAD8XWT0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2OG-Fe(II) oxygenase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWT0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032451">
        <property type="term" value="F:demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070988">
        <property type="term" value="P:demethylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032857">
        <property type="entry name" value="ALKBH4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12463:SF1">
        <property type="entry name" value="2-OXOGLUTARATE AND FE-DEPENDENT OXYGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12463">
        <property type="entry name" value="OXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-ketoglutarate-dependent dioxygenase AlkB-like" evidence="1">
        <location>
            <begin position="81"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="234" mass="26757" checksum="875F9232C5908D0B" modified="2024-05-29" version="1">MKDHYFKHISSLHPIRYNNTIFMTLRIIRNVGGIEGLHLATNCFTEEVERRIFTSIDESGYQSGKRTCGGQPTGLIRWPYDWPEDYNKLVNLVRDCGLLPDYVPPDYCLRLMYPPKAGFQFHHDSKYRWGEVIVGVNLGQEGEIMFTPDRPEDAFDQAAYTSEFASKSAGVGKSMRIKLPRRSIYIMSGPSRYVYKHGIKGIVVVDLLSDDEVDQKKESGCNENRPPDVIVIDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XX47</accession>
    <name>A0AAD8XX47_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_014295</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XX47"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="482"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1735229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="747" mass="84166" checksum="F3424F52F43CE55A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXL5</accession>
    <name>A0AAD8XXL5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Solute carrier family 35 member F6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_013902</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXL5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13146">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08449">
        <property type="entry name" value="UAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="413"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="449"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="474"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="103"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="179"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="120"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="182"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="196"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1735288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="504" mass="54891" checksum="DEB03F0D4D84DB7F" modified="2024-05-29" version="1">MYSAKVSFILGAMVLTGAARSVTAKIFYQLGFNHPLFLTLLYLIGQALSLIPYNIMVLLKKRGYRLVWDDHAILPGLSNRIEEEESVSIPSRHTVRTRQTLRYTTPDDEMERAESMASLDENKANNHDVESQRRKSTVSVRFASEECTNTSSAARASISFADGTKESDGAGAVMEDHLEAQGKSSTSLDPGSTSEKMAKKPSLLDRAKSARMSSKTLDTARRISASTHGLPTHSRTRSCHANIPWYLKPAVPAFFNLLNSAMRWASLVHVAASVAEMLISGMELVLSVCATRLVRGRKITWVRWVGVLVVTLGIVLVGVFDTNNVAGGETNDESTVNKQIIGILLILGQSVMSVIQDLTEEVFMQETAFPPPLLVGMEGAYGIVIALILYFPIAPLLGENPSDVASSLSEGNVIGLAIGWTLLVTVTGIFNIAATAVTSSMTRNVWKNMRTLLVWIMGLILFYATGSSELGEGWYIPGSFFILLSYGVMCVGIFIYYGKGARAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYE3</accession>
    <name>A0AAD8XYE3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013734</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYE3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="66"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="129"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="161" mass="17477" checksum="92D7C425B09D59CB" modified="2024-05-29" version="1">MSQHRSSLNTKLHLLPELSSSSSSIFLSSETESWRQYVPLAVSVAVIIDILLGSPLANLALGPMKRASEKGATGGNSEEGSDNGGEGGGSLFSSFGGKGRNVVDKSKERVDSEAIAQAALDKAMNTLELKRFLEENKTDEQRYEDVRKKIERQMDDLDNAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYP6</accession>
    <name>A0AAD8XYP6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013308</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYP6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="980" mass="110070" checksum="317384CF35B0419B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0L0</accession>
    <name>A0AAD8Y0L0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012243</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0L0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="123" mass="13689" checksum="ADE45DBFE7245347" modified="2024-05-29" version="1">MTAGLTTEVMNDEVYLAGIASTIDEKWNQIRIMYEPLICNSDPLHIAKRLPHCKPDSTANRTSWGVNAIQTSDPLHLLKRLLHVNHSVADDFLKTGGPYVNRSGPYLGDSNDFKRAQKAPVTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y108</accession>
    <name>A0AAD8Y108_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chitin-binding type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_011947</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y108"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055372">
        <property type="entry name" value="CBM96"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148">
        <property type="entry name" value="KERATINOCYTE PROLINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148:SF2">
        <property type="entry name" value="PA14 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24517">
        <property type="entry name" value="CBM96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Chitin-binding type-2" evidence="5">
        <location>
            <begin position="888"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="449"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="832"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="473"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="498"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="514"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="526"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="554"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="580"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1737080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="949" mass="102374" checksum="F83FCDF12EFB0802" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1E4</accession>
    <name>A0AAD8Y1E4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">tRNA nucleotidyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_011913</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1E4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1640.10">
        <property type="entry name" value="inorganic pyrophosphatase (n-terminal core)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052390">
        <property type="entry name" value="tRNA_nt/polyA_polymerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47788:SF1">
        <property type="entry name" value="A-ADDING TRNA NUCLEOTIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47788">
        <property type="entry name" value="POLYA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="DHH phosphoesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="9" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="287"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="323"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="450"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="538"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="217"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1737627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="627" mass="68677" checksum="FC642BFF7FE014AA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1N2</accession>
    <name>A0AAD8Y1N2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012103</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1N2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="237" mass="26983" checksum="F7F971E153C14184" modified="2024-05-29" version="1">MPSSTAWPTLGSTQIKPDSSACLHDDDNSITDENRTKHNIPCTTSCQCKFFLWNFISYIKFKETTSLVKENTIEGLGGKRFVRVKPGSLLERWYPQLRANQLKTDGCFLCGHTFREHLEYWWWCKKGRSNGGYSKFESVIGDGGSDNEHDSFHSKYVDELGTNKHKRGHKGVEVRTSFEGGVSYVVPPFDPLVDGKPKRVWTVMVLALARTSALVRLEDLIWLERIEYLKSKGVENG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y261</accession>
    <name>A0AAD8Y261_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Leucine-rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y261"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="316" mass="35879" checksum="9B98798B729B92A3" modified="2024-05-29" version="1">MAAEGDHIRRYNFTGEDDEVPDDVTHVTIAASVTVITEDTFLRHRSIIEVVCDVNVKKVEEFAFTRCPSLRRVIMPGVEIVERYAFYECDALTDVECGKLERIREHAFSDCKSLGSINLPSAKIVEYIAFRSCEVLADVKFGSKLESIKRGAFYDCRSLERITIPLKDGIITHDSIFTGCDNLKHVDLVEGELHETIAALQLEEWRNEMNEEINSINQILPTADAGEMNDEVGEKARAIRTWIRSVLGKIIHYIAGHQRLLDEQVATALELALPRDIVMNNILPFLELPSFTFEVGDHEEGEEEDYLDSEEEDDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y267</accession>
    <name>A0AAD8Y267_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Adenosine 3'-phospho 5'-phosphosulfate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_011341</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y267"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046964">
        <property type="term" value="F:3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778:SF8">
        <property type="entry name" value="ADENOSINE 3'-PHOSPHO 5'-PHOSPHOSULFATE TRANSPORTER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08449">
        <property type="entry name" value="UAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="287"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="325"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="380"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="401"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="16"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="405"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="418"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1738047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="428" mass="46355" checksum="4A7527B53EE167D0" modified="2024-05-29" version="1">MAIEIPSTLASISPTNNNNNGHHNHHSTNNNDEQHEPLIVTTPSATSQSPARQSTASSSASASIKHFVTIHKGILPIIGLFVFYIGHDALQERMFRFVDFKYGFFMTLVEVVIMLIGSTLANSSNSSGGDAPIHTLLLCNNNKCSSKNNTTTQQQRIIPMKTLLQISIVGILLALAHGLGNTALQYSSYPLKVAFKSCKLVPTMALGKCVTGRKHTALQYIAALIMGMGLAVLTAADVFSSKTKVQSISDQDSLSLLGPILLGISTILDSAVPNLQEQLLQSAKVNTSELIFVSNAIMCLVLVAYTTYSGELIAAWSYCTQHLDASMILVCQGLCAYFGLQCYLAIIRDHGGVAGVLFANARKVCTILLSFILFSKPFNVRHSIGLMLVFVGVYLGYKGKQQQQQKKKKGAHQKRKSKGDGKSHDHNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2G9</accession>
    <name>A0AAD8Y2G9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">PHD finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_011587</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045814">
        <property type="term" value="P:negative regulation of gene expression, epigenetic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15504">
        <property type="entry name" value="PHD_PRHA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045876">
        <property type="entry name" value="PRHA-like_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12628:SF10">
        <property type="entry name" value="HOMEOBOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12628">
        <property type="entry name" value="POLYCOMB-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0371">Homeobox</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="12">
        <location>
            <begin position="1070"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="112"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="225"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="317"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="408"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="484"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="573"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="654"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1046"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1216"/>
            <end position="1400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="50"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="233"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="275"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="317"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="332"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="361"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="408"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="425"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="445"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="497"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="530"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="713"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1216"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1249"/>
            <end position="1267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1277"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1306"/>
            <end position="1317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1368"/>
            <end position="1377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1379"/>
            <end position="1400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1737815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1400" mass="152354" checksum="7A6214817792A311" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y313</accession>
    <name>A0AAD8Y313_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Inward rectifier potassium channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_011164</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y313"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034702">
        <property type="term" value="C:monoatomic ion channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005242">
        <property type="term" value="F:inward rectifier potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034765">
        <property type="term" value="P:regulation of monoatomic ion transmembrane transport"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1400">
        <property type="entry name" value="G protein-activated inward rectifier potassium channel 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016449">
        <property type="entry name" value="K_chnl_inward-rec_Kir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013518">
        <property type="entry name" value="K_chnl_inward-rec_Kir_cyto"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11767">
        <property type="entry name" value="INWARD RECTIFIER POTASSIUM CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5 7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 7" id="KW-0630">Potassium</keyword>
    <keyword evidence="2 7" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <keyword evidence="3 7" id="KW-0851">Voltage-gated channel</keyword>
    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1737870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="308" mass="34856" checksum="E04FF5EEE3E94E4C" modified="2024-05-29" version="1">MYSKLMRLLAKAHVTFSSTLCVQFGRGNEGSTVRFGQFNFRASVAPAMAMKSISMEDLLNDSDEDTNKREDPLSTSDEGFPVIEFRMVNDRANHEGSEIWDAQIRGIIQLKKDVNPSNKPNAKATGGESTLDLDKKAYYQFALTPDSHPHFSRIWYARHVLNAESPLLKREIRDMIVQEGGKWDKDFNTASEIRQCLNEFISLRITLSGTSAVSANTVFAEHVYEYEDVVVGWRFANMVYEKEPKRKLLRRLFPFGRGEAAEVKGNCETFTKVDKALIHDIVPQPGDDYEDLAETSTLAQLGGLFKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4F6</accession>
    <name>A0AAD8Y4F6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010661</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4F6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="196"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="326"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="134"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="198"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="212"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="273"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="334"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="348"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="416" mass="46905" checksum="B9BC9AE4CB551019" modified="2024-05-29" version="1">MSSEDDDSNSTDAIVMERSSSCHSLRSMPLQKDDDYFYYHGDGGTEDDEDGDGETVDHIGLLIGPAIVQNRTTNMERDFRDSLRSMTSEVTSDWNDNDAGSQDELHSTTQECIGLKLQIADLKAQLDDQKFHYREKYNAAVSSLQDRNLSLECENVVLKQKLQESEDAALRERVEARRVERLLQDKVELMAREVQLSQDRKHHDQAMRRRSSTSGDTHNVSNCREEEYLPFPQSHNATRRLSASFVAVGRRPSLLESMCQSFRKNSNDIPAMSSSQVSSMGSDDSDTICHDSWANVDEINAQTEIFNKKSISKLFEGAAKKGCPESELVRSSRRNSTMCSQQPVPTSPRRKVQRRKSFALGERPPSLKDLFSKSRREEQGIDVESEIWDCPGENAALESSSNSVATDYHTVLTAGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2024-10-02" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4H9</accession>
    <name>A0AAD8Y4H9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010354</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="1">
        <location>
            <begin position="315"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1343" mass="150480" checksum="2158F959331A45A0" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4V4</accession>
    <name>A0AAD8Y4V4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WRKY transcription factor 19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4V4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="280" mass="29950" checksum="80EFBC0A028D771D" modified="2024-05-29" version="1">MSEEEDLAVLIYKSSKTAKARAAAATAAEEKGQINASSKGRRTSTQKRSSADQDDEASMDRPRKKTAKQGATKKKICSSKGCTNQVVQGGVCRRHGAEVKLCKSKGCTNISMKGGVCVRHGAKKTLCSSKGCTNNSLKGGVCRRHGAEFKLCSSEGCTNQAKKGGVCIKHGAKVKLCSSEGCTNRAKRGGVCRRHGAYRTHDGSTALRKEECALSMEQRRRNTVVKDARAILLKKEECVLGMGQRLNDATVEDALTKEECAGGTVQNSNYAAVKDAQIFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y519</accession>
    <name>A0AAD8Y519_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribosomal RNA large subunit methyltransferase K/L family protein</fullName>
            <ecNumber evidence="7">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_010493</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y519"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043527">
        <property type="term" value="C:tRNA methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11715">
        <property type="entry name" value="THUMP_AdoMetMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2130.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000241">
        <property type="entry name" value="RlmKL-like_Mtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054170">
        <property type="entry name" value="RlmL_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47313">
        <property type="entry name" value="RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K/L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47313:SF1">
        <property type="entry name" value="RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22020">
        <property type="entry name" value="RlmL_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01170">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041898546" evidence="4">
        <location>
            <begin position="29"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="domain" description="RlmL ferredoxin-like" evidence="6">
        <location>
            <begin position="113"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA large subunit methyltransferase K/L-like methyltransferase" evidence="5">
        <location>
            <begin position="344"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="64"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF22020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1739177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="600" mass="66262" checksum="F59ABFC642F1B67E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6L7</accession>
    <name>A0AAD8Y6L7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Gamma carbonic anhydrase family protein</fullName>
            <ecNumber evidence="1">4.2.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008952</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.-" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6L7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04645">
        <property type="entry name" value="LbH_gamma_CA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047324">
        <property type="entry name" value="LbH_gamma_CA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050484">
        <property type="entry name" value="Transf_Hexapept/Carb_Anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13061">
        <property type="entry name" value="DYNACTIN SUBUNIT P25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13061:SF29">
        <property type="entry name" value="GAMMA CARBONIC ANHYDRASE-LIKE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="180" mass="19140" checksum="8D2C3D06D10D37D2" modified="2024-05-29" version="1">MKGVYTLGNYVPQIASSCWVAPNAAIIGNVILEESCSVWFSATIRGDNKEAITIGPRTNVQDNSVLHADAKVPLTIGKDVTIGHQAMLHGCTIGDNSLIGIGATERIASLGTLLIPENKTIPDNSLVVGSPGKVIRKLSEEQVQGLKESADHYVKNAGWFKAELKPMDDDEAGGFTPSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6W4</accession>
    <name>A0AAD8Y6W4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glucose-methanol-choline oxidoreductase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_009474</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6W4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.410.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF134">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="353"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="3">
        <location>
            <begin position="440"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1739715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="578" mass="64727" checksum="EA59B9B513C61D18" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6Y0</accession>
    <name>A0AAD8Y6Y0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA polymerase alpha accessory factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009590</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6Y0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022100">
        <property type="entry name" value="WDHD1/CFT4_beta-prop_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19932">
        <property type="entry name" value="WD REPEAT AND HMG-BOX DNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19932:SF10">
        <property type="entry name" value="WD REPEAT AND HMG-BOX DNA-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12341">
        <property type="entry name" value="Mcl1_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WDHD1/CFT4 second beta-propeller" evidence="2">
        <location>
            <begin position="224"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="458" mass="49567" checksum="97CD8CEBEF4C0056" modified="2024-05-29" version="1">MTCEEEEDEDDSKSAVVVGGSLVKELSMVRGTAAEGIPVITSIVWIGNVLYVAHEDGEISVVSVSDEDVLVVEEEEMGAEEVEANLDDESLMGADDVDDSIKAKEGAMEESSHVNVKVNSRVLEDDDDDDDDDDLAQQGRGGASKFIDDEADAEDDDDDVTASMNVEKDTANQNGDDDDDKTQPIADDNNDYDDNFDFENHNDPLELGDVRASTNYSFPPLQPAFAPSSTPIGDSRRILCWNHMGVLTLRPDVEIDGNNLVDISFHDNAGLVGGRRPITFTDNVGFILGTLGDEGGLFASDLMEEEDDDDFDEDGLTAGLSETTRKAVKRSQKKLNGNDSAKGSSVYFHRFDTFGKTSDKDWVYALPDGERVLGCATGSGWCGVMTSRRLLRLFTVGGIQGPIIWLPGEPVTIVGRDRFMAVIYHRSMSPMQDGTQLLGYSIIDGVNGTTVATGDVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6Y7</accession>
    <name>A0AAD8Y6Y7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_009278</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6Y7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042284387" description="Thioredoxin domain-containing protein" evidence="2">
        <location>
            <begin position="27"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="503"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="449"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="460"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1740328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="643" mass="69901" checksum="7935838CC93880AC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y700</accession>
    <name>A0AAD8Y700_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008138</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y700"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="382"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="412" mass="45751" checksum="210D161E24DD533E" modified="2024-05-29" version="1">MASVSSKRRRTSTGNTTIEGTNSLFDLPSGILVHAATFLATPSRALFATALMDDAQDVVNQLSSAIAGDQTTVDFGDIEKELALNLSDGDINSALLCIDAVNKLKKLRITNCINITGIGLEPLRGSAVIQQIDLSLTCDGEGPSTLDLESSISFGIVLPILDSIIERGVVQHITLPRFGAMRDSNITSEGEVHQFLIRYNQMLSNRNRGGSCTNCDYDLVGVEWVEMDDTDQTYGLQNYICCRCMKIYCYLCRAVDMNIGSMLETCDQCERVCCQECTTTLFCDYCDIYHCADCKDVVECSRSDCNYKACADCMEICDKCKKCWCSDCFTVQSRCPICPERLCSDCSREKGVTPATFCGTCGTDHCDSCCSFRCPRPILNQNKWLKQENDRLKTEIRRLKDENRRLLASQGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8H3</accession>
    <name>A0AAD8Y8H3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nitrogen-fixing NifU-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008196</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NifU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8H3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.130:FF:000003">
        <property type="entry name" value="NifU-like protein 3, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="entry name" value="Fe-S cluster assembly (FSCA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001075">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11178">
        <property type="entry name" value="IRON-SULFUR CLUSTER SCAFFOLD PROTEIN NFU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11178:SF15">
        <property type="entry name" value="NIFU-LIKE PROTEIN 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01106">
        <property type="entry name" value="NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="Fe-S cluster assembly (FSCA) domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NIF system FeS cluster assembly NifU C-terminal" evidence="2">
        <location>
            <begin position="77"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="187" mass="20048" checksum="F30EE8AA736B8923" modified="2024-05-29" version="1" fragment="single">MDEDELDDYLQMMAESRAATSSATPAASPLFVDTTTASSVEAADDDSTIISPFESEQAAATSTIDDQQPLELNKENVDKVLDEVRPYLISDGGNVAVDNVDAETGNVYLILEGACGSCASSTVTMQMGIERVLKEKFEERLGEVIQVDPDNEDGADGGKPKELTMDAVQVEVKRISQAITAMGAWYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8K6</accession>
    <name>A0AAD8Y8K6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA repair protein RAD51 homolog 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_007226</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8K6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033063">
        <property type="term" value="C:Rad51B-Rad51C-Rad51D-XRCC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033065">
        <property type="term" value="C:Rad51C-XRCC3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005657">
        <property type="term" value="C:replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000400">
        <property type="term" value="F:four-way junction DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000707">
        <property type="term" value="P:meiotic DNA recombinase assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052093">
        <property type="entry name" value="HR_Repair_Mediator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46239:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46239">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 3 RAD51C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecA family profile 1" evidence="8">
        <location>
            <begin position="162"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1741653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="483" mass="51879" checksum="46F18D53A4FB6B03" modified="2024-05-29" version="1">MRIDIKYYGDNVEEMMTVAEAINITQTQQKLLSIPLLSLPLRPSTLTALLRRGFATTGDIMINNTNTMKTGNDDGGIENLAEELGCSVSQSADYVHEINDALYSIGLPPVTANTTIVGRTDGTTKINTATLRSTNNIPATAASLLRSKLNSHMQQNSNSSSTARQIVSFSQPLDMLLGGGFALSELTEIAGLPGSGKTQLAMQLCVDARLPGKYGGVEGCAVVIDAEGSWSGAGVDRLWSLAGALVDHVKSSALRKMEANKAKEMANGGGANTDTTAPEELVPTWFTPESILDGIHIFRVHDESEQTCTLYNLPQFLQDQEEKGKPVKILVIDSLAFHYRVASSINSSNKGNFLSTTTSLTRMAAFLQELASEFDLAVLALNHLTNKLDKDSTGAGGMKLVPALGESWAHSVTSRLMVDFYHRHVPNGASPGGVMGEVRTCSLIKSPHKPNGTACFMITEKGIRGLPPQFIQQAEEAKRARLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8S6</accession>
    <name>A0AAD8Y8S6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chitin-binding type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_007331</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8S6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21113">
        <property type="entry name" value="AGAP001705-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21113:SF4">
        <property type="entry name" value="CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="3">
        <location>
            <begin position="43"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="484"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1741758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="594" mass="66081" checksum="B2ACBB89F5013173" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8T9</accession>
    <name>A0AAD8Y8T9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008334</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8T9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="105" mass="11601" checksum="2FEB2583527FDF08" modified="2024-05-29" version="1">MTSEQPPPPPHRSDHLHLLEGTLLHRSQKSNIYKKNIRMYTIFDMSGSAGASLEVGGIGSLQCYRFVNLKSKKEGDLAYSSTRFGNKGGDSNDTMIGSGVKRRED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9K2</accession>
    <name>A0AAD8Y9K2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal silencing factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_008013</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Iojap/RsfS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9K2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090071">
        <property type="term" value="P:negative regulation of ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01477">
        <property type="entry name" value="Iojap_RsfS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004394">
        <property type="entry name" value="Iojap/RsfS/C7orf30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00090">
        <property type="entry name" value="rsfS_iojap_ybeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21043">
        <property type="entry name" value="IOJAP SUPERFAMILY ORTHOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21043:SF0">
        <property type="entry name" value="MITOCHONDRIAL ASSEMBLY OF RIBOSOMAL LARGE SUBUNIT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02410">
        <property type="entry name" value="RsfS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042223867" evidence="3">
        <location>
            <begin position="22"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="24"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="228"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="228"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1741535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="263" mass="28653" checksum="272CD6B7056BC893" modified="2024-05-29" version="1">MRLTTTLCILALSTSPHDVSAFQTSQQSTITQQPQSPSSTTLYAGRKGNRGTPKAISENTSRRPTRSQVHDVLEGITSEPSFPHSVDPTDLPPGHISADPLVPLVHTIVHAADMRKATDIVALRVTQCTSLTNFIIVISGTSRPQNQAIANSIKSDVEELYDGKRCLGKGIPEGSADSGWILLDYGEVMVHVMTPKSRLFYDMEGQWRERGGKELDLGDVILDEFGGTSVGVGVGGESSEGSEEERSMRERLDVEKEEDPFWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YA17</accession>
    <name>A0AAD8YA17_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007387</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YA17"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="530"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="556" mass="60633" checksum="6FF7C85EFB116275" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAB0</accession>
    <name>A0AAD8YAB0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006316</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAB0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="486" mass="53113" checksum="55CBD1AA64E526E1" modified="2024-05-29" version="1">MRARNLGHIGVFAAIVVGMVIVVLAGEKWRSISRSQSILTTSPEQPTSQPSLLPTMLPSSSSAPSSQPSETPSSFPSAGPTLSASPSSQPSLRPSISAAPSTQPSSTPSLSAMPSESPSFIPSAIPSASSAPSEFFGTSTTIVLDSRSSSAMVAVILIIAFSYAAMYMCGKDNQPKDPGVGNTIFSVIFRKNGRKYERDPESDESEILSDSISRHESDETIDTNNVYPMNCAANGINTRERETDMEIPNFNGISSSPIQSNVNSTSEADTKMQDIDLEDGTNSILPNSIAISKYFGISPLKTPNVFKKRQQSKFRNERLRDNQDRNSSVYARGNAPLRRISRHAQERTHSLADDMMDESDHITPKESPVSFYASAKYGLNPDRPHAKESSKETDISSPDSEGGIECLAYANPKEQKKYKIDVYDLHKDRALRRPETITIKSDGSSTIEWDGDLASKDNLREFDDIMVKMECHGIEVSTRYDSDDID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YB83</accession>
    <name>A0AAD8YB83_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_005892</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014012">
        <property type="entry name" value="HSA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46459:SF1">
        <property type="entry name" value="E1A-BINDING PROTEIN P400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46459">
        <property type="entry name" value="E1A-BINDING PROTEIN P400-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07529">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00573">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51204">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSA" evidence="9">
        <location>
            <begin position="5"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="8">
        <location>
            <begin position="1414"/>
            <end position="1462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="60"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="854"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1046"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1291"/>
            <end position="1316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1625"/>
            <end position="1691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="106"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="858"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1047"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1641"/>
            <end position="1656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1657"/>
            <end position="1666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1743271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1691" mass="185367" checksum="00F707E4227DBE0C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBD5</accession>
    <name>A0AAD8YBD5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">TraB/GumN family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">QTG54_006922</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TIKI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBD5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030178">
        <property type="term" value="P:negative regulation of Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14789">
        <property type="entry name" value="Tiki"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040230">
        <property type="entry name" value="TIKI1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002816">
        <property type="entry name" value="TraB/PrgY/GumN_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31120">
        <property type="entry name" value="METALLOPROTEASE TIKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31120:SF6">
        <property type="entry name" value="METALLOPROTEASE TIKI HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01963">
        <property type="entry name" value="TraB_PrgY_gumN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042290711" evidence="15">
        <location>
            <begin position="21"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="395"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="400"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1742357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="458" mass="49195" checksum="6DE341FBC9D1981D" modified="2024-05-29" version="1">MFPLKSTLLSFLLTTSPAEGVNVKQLTDQSSGHMIGGMMDISLIQASHRRKVQAVDEIQTDASPCPGNPFLWKIIEDESGKHVGFGVGTLHFPSDLALTDDAYGSIIHAVEDSCGIYGELDLMDGMVAQELAGCVGDLNVEAAKIADIQDEDLRLSYENVSREFAVLAAGAGADAESIDIIHQQLLQLSLYSILSFITFSNTPEYEEYFLQKLFGMPPSSLDQTLLSLGRPNGGVEEVSTQCEILAALILPPEELNEAELRLALNQTFSGILNMYKCGDIDTFTIAQEMNFEQSMAGSEFMISLLDTRNEQMAAGIDEILKVSDDRVLFAFGASHWTVGEKSLDVLLKGYGYSLEYVPNYAKDDAEDLSNEECEVVFNSIDGVFDLIGVSNSTASTPVVSGDSESPSASPVSSPSKSTASPISSSDNTASPVSGGSSLNVFKASITPMLCAFGSMHLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCI2</accession>
    <name>A0AAD8YCI2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005919</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCI2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1743298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1179" mass="134831" checksum="6BAAE904D9683184" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCP7</accession>
    <name>A0AAD8YCP7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lactonase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005329</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cycloisomerase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCP7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050282">
        <property type="entry name" value="Cycloisomerase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344:SF1">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75011">
        <property type="entry name" value="3-carboxy-cis,cis-mucoante lactonizing enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="415" mass="45147" checksum="DD02F53E91A08AFD" modified="2024-05-29" version="1">MSLNDYKYVGLVGCYTKEGQADPFEGSHGGVPHDRSLIGEGVIAIGVDYDGRLVYLNDGAPIITAKELRNPSYLTILENVETVEGGVGVCVVSELEKGMWQPFKLSSSSNDDAGTTIRAKPAGAPMKSGGEYPCHITSARVVGFDDEGVLSIFSSQDFESAFKPEAKFMFGDGSKADLNRQQCSHAHSTSIASTCDPYSPVDICVADLGSDAIVQFSIKSGRVRETGRLAAPQGSGPRSLMFNPRHNHLAIVSLEMTGEVWLIRKRSHDGCLEGLGSPVSILPSDWPSSDMTESQFNLGRWASDALWSEDGKYVYAAARLHDSISVFELKYRVEKYRDDAVVAEGLELVQRIPTQGQTPRCLCMSDCGQFLLVAHQHSHDVSSFERNEVNGTLSFVDRITLPNAACVKLIRADKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD06</accession>
    <name>A0AAD8YD06_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SMP-LTD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004737</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD06"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042288854" description="SMP-LTD domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="431" mass="47936" checksum="461623C0E914B46E" modified="2024-05-29" version="1">MASTLVHLLILFGGFGQLWSFSPRYTSFNTVQGRHKSQLGAGSSAGEEEGIISVSIQKRFPDTTPEQARDAWMDYHWKKGGGLPIVIVSSDESPKERTILPTLMKEQLLDDEVEENQEDESHVEISYKVTDAGPLFPGIIPDTHSANVTFEYTNQATVMNWDVSFETTKFYTLYEAVTQWTVGTAATTVEECLTLPRRLNVKTVIDGDIDPFLARKECLEFVWASGGGLPLIPPIPFGDILEEGGGSARRNLLRIPPLITESIVDTTTTEEQSSFQYQLNRPGLTTFPFLLHTHIGNVSFTSTAQGLAIDWEVEFRPYQIAKPIVEKLVEMTVSTLVRNLRVKLLEPDAVVLIKPPRGNANLTMGLEEFGKVSKSSWLGGVLESHLSDVRSTKDQTLSLIQPWTWGRSGEGDELDIVQYQWTGGQSVEEDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD12</accession>
    <name>A0AAD8YD12_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004749</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD12"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="158" mass="18054" checksum="817EFE2B347B48F0" modified="2024-05-29" version="1">MFHSTGQCRIKVVAVITDDDDDEKAECIINLRSEEEDDDLAQFLEHDFDPQKIDYFDVIELETCKAIDLKKELVEIQGDQVLTDSDVKVVFVAISETDFLDGTCQEELDKLQYTLEGLRCSDIEEFEDFITIAVDSSNECKANEMKEAVLEENAQLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEQ2</accession>
    <name>A0AAD8YEQ2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Xanthine dehydrogenase</fullName>
            <ecNumber evidence="19">1.17.1.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">QTG54_005664</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
        <text evidence="15">Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="15">Binds 2 [2Fe-2S] clusters.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the xanthine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.1.4" evidence="19"/>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004854">
        <property type="term" value="F:xanthine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.365.10:FF:000001">
        <property type="entry name" value="Xanthine dehydrogenase oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.365.10:FF:000002">
        <property type="entry name" value="Xanthine dehydrogenase oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.365.10:FF:000004">
        <property type="entry name" value="Xanthine dehydrogenase oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000012">
        <property type="entry name" value="Xanthine dehydrogenase/oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.120">
        <property type="entry name" value="[2Fe-2S]-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.50">
        <property type="entry name" value="Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.365.10">
        <property type="entry name" value="Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.50">
        <property type="entry name" value="CO dehydrogenase flavoprotein, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_MoCoBD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046867">
        <property type="entry name" value="AldOxase/xan_DH_MoCoBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005107">
        <property type="entry name" value="CO_DH_flav_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036683">
        <property type="entry name" value="CO_DH_flav_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002346">
        <property type="entry name" value="Mopterin_DH_FAD-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45444">
        <property type="entry name" value="XANTHINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45444:SF3">
        <property type="entry name" value="XANTHINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01315">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03450">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00941">
        <property type="entry name" value="FAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="MoCoBD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20256">
        <property type="entry name" value="MoCoBD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000127">
        <property type="entry name" value="Xanthine_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01092">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55447">
        <property type="entry name" value="CO dehydrogenase flavoprotein C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="CO dehydrogenase ISP C-domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54665">
        <property type="entry name" value="CO dehydrogenase molybdoprotein N-domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="Molybdenum cofactor-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 15" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="7 14" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9 15" id="KW-0408">Iron</keyword>
    <keyword evidence="10 15" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 15" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="11" id="KW-0520">NAD</keyword>
    <keyword evidence="8 19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="17">
        <location>
            <begin position="32"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="18">
        <location>
            <begin position="362"/>
            <end position="566"/>
        </location>
    </feature>
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        <ligand>
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            <position position="1314"/>
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            <name>Mo</name>
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            <dbReference type="PROSITE" id="PS51387"/>
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            <dbReference type="EMBL" id="KAK1744067.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1588" mass="172683" checksum="1DA793FD2E785BC2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YF51</accession>
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        <recommendedName>
            <fullName evidence="5">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="3" type="ORF">QTG54_004843</name>
    </gene>
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        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
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            <taxon>Eukaryota</taxon>
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            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
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                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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    <dbReference type="EMBL" id="JATAAI010000007">
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        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
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    <feature type="chain" id="PRO_5042090346" description="SAP domain-containing protein" evidence="2">
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            <begin position="28"/>
            <end position="1036"/>
        </location>
    </feature>
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            <begin position="807"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="830"/>
            <end position="847"/>
        </location>
    </feature>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
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</entry>
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    </protein>
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        <name evidence="1" type="ORF">QTG54_003711</name>
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        <name type="scientific">Skeletonema marinoi</name>
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            <taxon>Eukaryota</taxon>
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            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
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                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745787.1"/>
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    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1745787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="576" mass="63909" checksum="E90C153681167B67" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGX7</accession>
    <name>A0AAD8YGX7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Mitochondrial carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_003697</name>
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    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
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            <taxon>Eukaryota</taxon>
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            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
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                <person name="Kourtchenko O."/>
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                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
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    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGX7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="99"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="206"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1745773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="291" mass="31537" checksum="D73DFD4264CC43F3" modified="2024-05-29" version="1">MNLAKEFAAAGPGCAVANGLLNCFETTKVKLQLHNHAKPVYDTPTTRGVMMQIAREEGIVRGLMTPGLSASLTRSMLYGSYRVGLYSTTKEWLSGDGKDNLSHRMLSGMFTGGLGSMISCPLDVVRTRMQADAGVVRNGKYVTGLKKGDAVRYRGMISAFLTIFKEEGLKKGLYRGASVTVLRASLLNGAQLASYDTLKRSLNWNEGPALHFFCGFASGVIAQTAVMPVDTIKSQMMLGSGWKDVFATLRSNGPFYLYRGLAPACAGQGLIMVLQMPLIEEFRRLLGIKAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YH41</accession>
    <name>A0AAD8YH41_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_002790</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YH41"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="371"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1746183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="415" mass="46808" checksum="D36B75B06E03486F" modified="2024-05-29" version="1">MSDSSSSSSEVSDDVSLEFTEDIFLDDLQLLRGNDSSVTDLKVSGLFPYVQDMTGEDWEQLGRDISNNRHLKKITFVAALDDHTMTSLFRGLIISSSTDEMTFTNNRSGVNGIQTMVPFLQNAINLLELSFFHDNIIGRIHPIKRLTFVSCGLSSIKIDDDYVPNNLQTLILRGNNINADGCREVAKLMRMEHTKLEHLFLNDNKIDDEGISILANALRTNTSLSLMNLQDNEGITIEGMKLVLKLLNDISSIKATLQSNHTLFSMTFNDSFENTDIATEIRRVLQINRDNLDNPDMTGKLKVIHTQLDSKQRAEMCRLQGVQNSGKPLTEFGPLLLPEVLEIVGKYHGLSECYESFRTCVADLWTIIDRKEVLRQQKAELAIELDALVAKRLEVEKQMSNVEMEIDLMEQAELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YH81</accession>
    <name>A0AAD8YH81_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Citrate transporter-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_002850</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YH81"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="entry name" value="Regulator of K+ conductance, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051679">
        <property type="entry name" value="DASS-Related_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43652">
        <property type="entry name" value="BASIC AMINO ACID ANTIPORTER YFCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43652:SF2">
        <property type="entry name" value="BASIC AMINO ACID ANTIPORTER YFCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="TrkA C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Citrate transporter-like" evidence="8">
        <location>
            <begin position="61"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1746243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="168" mass="18077" checksum="EF479F5393639444" modified="2024-05-29" version="1">MHFRTKYGAAVIAVHRNGTRIQDYPGNIKLNSGDVLLLEAGPTFIARNTDNQRSFALISEVKDSQPPRLNKLKWALLITLIMLVFATIGPMIPSMAELNISNLFVLGLIASIVMVCAGIISQQECRDAVNWEVYITIASAYGIGSALTESGLATVIANFLVKIGVGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHS0</accession>
    <name>A0AAD8YHS0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_003698</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHS0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1745774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1018" mass="114817" checksum="6DC36E4713F84D58" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YI12</accession>
    <name>A0AAD8YI12_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YI12"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="245" mass="27432" checksum="1D2D5592BE67D995" modified="2024-05-29" version="1">MKPLPVKGSTSRKGNQQSERIDHRVPSREVNESPVPAPAPTYHKTKKSNTPRMPEQRIDAQSIDTYDSLLSESSQFSFFGLWPTTSRHVRPDTSGTTPKQAYHPSRLIPGWNYSSVASATTYTDESSHAFSHALKEFDLSTLLGAFTDLGGQYSVREDQSSRDKQSSRGDQSSRDDQSSRVGSVSWASSIAGYSSWADDYSSAASSYFDDYSEDDVSTVMSNEPSKSKLLQLNPMKKFRRRRFEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YII4</accession>
    <name>A0AAD8YII4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002548</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YII4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="18" mass="1895" checksum="F665001DF7D787DF" modified="2024-05-29" version="1">MSEGTQAKTQTRVQDAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIR2</accession>
    <name>A0AAD8YIR2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GDP-fucose protein O-fucosyltransferase family protein</fullName>
            <ecNumber evidence="2">2.4.1.221</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002166</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.221" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIR2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046922">
        <property type="term" value="F:peptide-O-fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31469">
        <property type="entry name" value="OS07G0633600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31469:SF8">
        <property type="entry name" value="OS07G0641000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042031217" evidence="1">
        <location>
            <begin position="21"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="267" mass="31025" checksum="2822EAFA07EF7DDA" modified="2024-05-29" version="1">MRISFEIVVLLAALSGRTLVLPPEQVMYLLQPKPGDKRQGRRQYTDYYNLTDNIDLLRHVPIISAEEFLHLEGGEDGLVPLTGYNDTWTKHLYTVSTSCEERKKSDVFCEDLYDHYASHGLVGPITSEVKYANCLVFDENVFLNGNNQIDKLAPDVQKRIKAFCGDKRYPVYYNMTMHDTPVWHFETRDLDHRLLVHFYSILFFTDGKVEISTSDLQGTSFDITMKSFVQQERLYLHCNMKIASSLEQTIPWLILIQSWLAAIHRYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJU0</accession>
    <name>A0AAD8YJU0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002183</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJU0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="154" mass="17335" checksum="FBE89394A39638F6" modified="2024-05-29" version="1">MTSNCRERERQEDVAPAASQKRDNKLKTCTAWKSVRYCNMLHARRSIDQNTNDHERKDSLNYMTKFCTSSLLAATMVIAPLFIALSATDPSSSIAMACCSNMICVGSMMPIRARDERIAASNMSILATSSTGIARRSQHECYEKKEVMGFMRYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YL22</accession>
    <name>A0AAD8YL22_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Zinc-dependent peptidase, M16 (Insulinase) family</fullName>
            <ecNumber evidence="13">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_000282</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M16 family. PreP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="13"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YL22"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000034">
        <property type="entry name" value="presequence protease 1, chloroplastic/mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000009">
        <property type="entry name" value="Presequence protease, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013578">
        <property type="entry name" value="Peptidase_M16C_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055130">
        <property type="entry name" value="PreP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016">
        <property type="entry name" value="PRESEQUENCE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016:SF13">
        <property type="entry name" value="PRESEQUENCE PROTEASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08367">
        <property type="entry name" value="M16C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22516">
        <property type="entry name" value="PreP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01264">
        <property type="entry name" value="M16C_associated"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042232097" evidence="11">
        <location>
            <begin position="20"/>
            <end position="1116"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16C associated" evidence="12">
        <location>
            <begin position="566"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="570"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1748343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1116" mass="122061" checksum="611F2791F589DFDF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YL96</accession>
    <name>A0AAD8YL96_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_000022</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YL96"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1748083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="63" mass="7011" checksum="A41AB9597FDEADE8" modified="2024-05-29" version="1">MEDWVNDLEGRVVGNDIRPALGEFKEQLTDALGEEGAIAKKEEEGALLGFLRTGYNLYAIRNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMB3</accession>
    <name>A0AAD8YMB3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF1279 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001823</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMB3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045866">
        <property type="entry name" value="FAM210A/B-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21377">
        <property type="entry name" value="PROTEIN FAM210B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21377:SF0">
        <property type="entry name" value="PROTEIN FAM210B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="230" mass="25420" checksum="720D232F3904A309" modified="2024-05-29" version="1">MLLATGVRGAMKGRPMASLLGQSLPCRNTVNGGAVKPAKILLCTHHYSTIPMHKFQSSYSMPSQTQIQSMRASSSFSALPPDEEQAEKERVASLTQYQKEMELRQLDSELARLQTLRGINTGELYTLRGKFKMLSRDYGMGFLAWYWSVWFATAGLSYVAIEVGGVDPFMVAAKVESFLGWEADAIAGKLDPTLGQIGLVIAVNECLEPLRLPFVVMTTKPVVNFFTKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMK2</accession>
    <name>A0AAD8YMK2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Bifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase</fullName>
            <ecNumber evidence="1">6.3.3.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_001975</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.3" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1748012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMK2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004141">
        <property type="term" value="F:dethiobiotin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03109">
        <property type="entry name" value="DTBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00336">
        <property type="entry name" value="BioD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004472">
        <property type="entry name" value="DTB_synth_BioD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43210">
        <property type="entry name" value="DETHIOBIOTIN SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43210:SF5">
        <property type="entry name" value="DETHIOBIOTIN SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13500">
        <property type="entry name" value="AAA_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1748012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="338" mass="37486" checksum="B85E507078FA70F1" modified="2024-05-29" version="1">MRVGQCRLLRRVASRTGATCRFFSDISSSGSSVHLHPHHRVHLLFGANTDVGKSVISSGLVRAAASAACDEWQSPVNYIKPLQCGGSDESFVLLNNDQQEGRRMNDIRCQTLFSWKTPASPHLVSRWENAPVSDEEVVSKLSAVLRDIDNTKNNDADNNLETASITTIIESAGGVLSPSSSSPFNKTTTADHWGWSTQADLYAPLRIPVVFVGDGKLGGISVTLSSLEALWTRGYRIDAVIFIEGESDADNNEYDSIQFGKGNAEALREYMSMRHQIDPSKEVYDELLRDDNAIVCLPPLPPMPIPLDEWYRSNEGSFLRLHQLLDKKWIGAEEEHKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMP3</accession>
    <name>A0AAD8YMP3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">CTD small phosphatase-like protein 2</fullName>
            <ecNumber evidence="7">3.1.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_000089</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Probable phosphatase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CTDSPL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMP3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000015">
        <property type="entry name" value="CTD small phosphatase-like protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011948">
        <property type="entry name" value="Dullard_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02251">
        <property type="entry name" value="HIF-SF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="6">
        <location>
            <begin position="391"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="191"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="260"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="260"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00037324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1748150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="573" mass="62537" checksum="FF28F09B4B44F017" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YNL1</accession>
    <name>A0AAD8YNL1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YNL1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="165" mass="18953" checksum="0B40D6A4C14A5689" modified="2024-05-29" version="1">MVITAKIRDATRVAQKKKCTQPWNPEYLKHIQSGKVLRYHHFHALVKAETEEQQEPEADDNNNSASTAKRQKTSSTSNEQQKDNPQQMNTNHEDTPQETNEQQEQDTPQVTQPLLEISGMFDSSGHFTNKSVKYIEQQLKPTYKDCIPNDNDKRVAGMLMLLGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPF8</accession>
    <name>A0AAD8YPF8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">S1 motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_000926</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPF8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050437">
        <property type="entry name" value="Ribos_protein_bS1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10724">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10724:SF7">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS1C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="123"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="200"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="253"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="200"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1748987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="283" mass="31648" checksum="2F22AE324DAEEB67" modified="2024-05-29" version="1" fragment="single">FWKPRKELSSLFVGERLFATRLPKCDLLDGKTGPKLFFECGVGKKTRGEWSIVNGMIRIPGKRGMKPSVIRKKAKKIPNDSLIEVYVSKIRLDHGSFEVCLSREEALSSYKKEKVSASKLMPGEQLSGVVRDVRPYGVFVDVGANRKGLIHISTVAKSQDCYINKEEGLKSAGFARGAPVQVVVLNNEKKRLEFDLYVPEEEPIPDESSDETTTIELKSEEDEEALAWGASNNEPTKEISTVEADMWAAYAAYESNNAEEDDDDDDYYDEDEDIEDALGIGSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPK5</accession>
    <name>A0AAD8YPK5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">7-dehydrocholesterol reductase</fullName>
            <ecNumber evidence="16">1.3.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Sterol Delta(7)-reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">QTG54_000894</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERG4/ERG24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.21" evidence="16"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPK5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047598">
        <property type="term" value="F:7-dehydrocholesterol reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016132">
        <property type="term" value="P:brassinosteroid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006695">
        <property type="term" value="P:cholesterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001171">
        <property type="entry name" value="ERG24_DHCR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21257:SF38">
        <property type="entry name" value="7-DEHYDROCHOLESTEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21257">
        <property type="entry name" value="DELTA(14)-STEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01222">
        <property type="entry name" value="ERG4_ERG24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0152">Cholesterol biosynthesis</keyword>
    <keyword evidence="4" id="KW-0153">Cholesterol metabolism</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="10 20" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="15" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="11" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="14" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="5 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="351"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="375"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="441"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="473"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00038851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00042688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAK1748955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="525" mass="58937" checksum="66E27EE51BF95EBB" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPL5</accession>
    <name>A0AAD8YPL5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPL5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="233"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="334"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="11"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="233"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="245"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="256"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="438" mass="48170" checksum="00375AD673764F4E" modified="2024-05-29" version="1">MGRMKRNLSFGGSSNKNNVTSTGSVSSSKSSGRFGRKKKQSYRSGGDWESVQSAGSRTRSMSRSKRMLRNINTNNNSAASVTTMDEMDSNESMTLKGISMGRRRNPSAPIRRPMQEEEGESRVVDEPVEMSLAELRSMSESELEQSMLKAGVPSADISSTKDAVMQLGIDSGTAEEKRRGSLVAFARSFTETNATTSPIHNSSASMDASDATLLESKSISRKSKLEKITELQGEKSTLKKENKALKKTMKKKALKMKIEANAKEKRESETVEDSAKGSLHSVDHDISVGTDTDSKATRRKESSASQRSRDVSVKDVSNLKKMMKKQRQEHESTEFRLKAEIEILTKEVDGLQRELSLALESADDAEKRVDESHEAASKLKRKMRTMSSKLNGLTEEANARDKLIETFTKLLVDKNGGENGVAAVEGKLELAQLIHTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPZ5</accession>
    <name>A0AAD8YPZ5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_001104</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPZ5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="207"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1749165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="255" mass="28709" checksum="5ABBACEDB1FE6F57" modified="2024-05-29" version="1">MAAFGLPDLTLAEAISIAPNPYPIIIRSKAECGISGTGYVATLTNKFTRCKTLPHPHQVVVNAIGQELTAADVLPVTEEDWPTLRDFLHKQKVLGSIGFKTDTTFDEMMVAGFRCLLDSNDIFELASFPTVFPMGRGAFCEKRPTPLLFPEYYKHICRMSTFNPESSVNWLVWCQLIEAAALIVEKKVRDGSMQNERRHFSFLQSCCAICGPRDEIKRCSRCHVIGYCGREHQMEDFNGGHKKLCKKYQRPGDPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4B9</accession>
    <name>A0AAD9D4B9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sel1-like repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015974</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000051">
        <property type="protein sequence ID" value="KAK1733257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4B9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="161" mass="18315" checksum="E204CC311EE9CE56" modified="2024-05-29" version="1">MDHMKRVEVNDPFAIDQMGIMRYYEGNYEGAFKYYTKAAELGDVASQYHLSCLYREGKVKMDEKKEFYQLEEAAIGGHPTARHNLGCREAENGNYERATRHLIIAVNLGHEPSIEMLKANYTKGNVSKADFAAALRAHQAAIDATKSPQREAAEKWEKQQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6L5</accession>
    <name>A0AAD9D6L5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein xylosyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013528</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6L5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041901472" description="Protein xylosyltransferase" evidence="1">
        <location>
            <begin position="30"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="317" mass="35861" checksum="C5CA18FC99CF9E73" modified="2024-05-29" version="1">MRSLGLRLLAVGVVASICHLSLYFSFASGGESSSNSSNSNPGAVEVKGKDPNGIIDTAIIITSSWIPSHPSTLMVEMVVHSIDLMITSLHPSTPIFITIDQFRLDGDIEQIQNRSNSLDQHVLNLYNIYLINPRVHILPFMAHSHVGGSVAKAMDIIERHFPSTKYLYYLQHDYYFVKEVDHTALIHAMETHDSINYVFFRNEKRPLNRIKPCGEETSIEYLDNVHSNDNDNQTATTSISTKRLLLPTATYTDNNHLVRFKWYKDTIASMISLTRFPENPLQKRAMDECISGRSMGLYAYNDNHVIEHLDGRKTSFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6S9</accession>
    <name>A0AAD9D6S9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_014353</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6S9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="7">
        <location>
            <begin position="17"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="82"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="282"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1734893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="310" mass="35168" checksum="1958F22F3692F57E" modified="2024-05-29" version="1">MSSKDNHEVDVATDSCCASCGIAEVDEIKLKNCDDCDLVKYCSDKCQQDHRPNHERACKQRAAELRDEILFRQPEGSHLGDCPICCLPLPLDLTKSTMMSCCSKVVCKGCVYANCRRELGGRLDFTCPFCRHPFPETKEEGYKINLKRVEANDPVAIEEVGRRHCQEGKFDTAFEYLTKAAELGDVNAHYHLVHLYEKGEGVEKDEKKRLYHLEEAAIAGHPEARFQLACYEGGRGRCDRMVEHLIISANLGHDESIKGMKMLYKEGKVSKEDFASALRAHQAAVNETRSPQREEASKAWQRQKLREQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6V7</accession>
    <name>A0AAD9D6V7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_014125</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6V7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16448">
        <property type="entry name" value="RING-H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="259"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="116"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="192"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="222"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="233"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1735059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="333" mass="38003" checksum="73672D7B4DECBDD9" modified="2024-05-29" version="1">MSRDYSGVFESRYAAFIIWSIFILAFIIVPIMYVPLKFLIGRICRRCICLASICGLQQDSDEVGSDRRPVYSVWDVEYVHLSHSKKSLISEIRAREIYKRLAPFSLELKADNMISRQSSEDVHHEDEYGGQEEYNASQETPDEANHFTLDVTHGEGSSSTDDTETSTEASKSEAEANYTHVCLPLPGYNKNGLRKPKKKKSSSSTPDNNSRIGLVLFRRQKKDSSKQTKELSGEDDDAEVTEQDITQQKDDRREVPIFCAVCLGEYETSERVCWSSNTECTHVFHHDCMLQWLKSLGKRACKQQRFSENPSVQQVMNFTMDVHAVVNRSLTNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6Y0</accession>
    <name>A0AAD9D6Y0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Hemerythrin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013021</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6Y0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12108">
        <property type="entry name" value="Hr-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.520">
        <property type="entry name" value="nmb1532 protein domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin-like" evidence="2">
        <location>
            <begin position="75"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="310" mass="34625" checksum="549720F77D9845D0" modified="2024-05-29" version="1">MSASGGASSKDEISSSRRSSLSANRSPSMVLGPRVSSVKIINPTSLFVPSKLTSEVFSTENPPLDWADAGLLIPHEAIRRQMAMMLQSVNAMSDSPEDKEAWKLTLFSKWYIEYLYESVHEHHDAEEKIYFPWMITKTTIPEKEFGQSHEELMSAMAEIKQCCAEIIKKGGKGCSAQVATLKEKVPKFDVDMRAHLKEEEETVPALLRENFTHEEEGQIVEQILQAGGLGLAKKFLPAVLLAAQEWTTDAFYADFVGSIPPPIKHLVDKYFLPDFENVVMIMRDAPTLASEPKLKRVPCCGIPFCFPCLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7T2</accession>
    <name>A0AAD9D7T2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1735989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7T2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="119" mass="12026" checksum="C1AF54F14020F9C1" modified="2024-05-29" version="1">MIAAQVLAAQHQAAAAAAAAAENNGQVKANPQPQPAAKPASVSVSTETSVASAPSTKRAASSPPKKRSSNSKSAATISSSGVATMSTATSTSRPSSKTMIAEWEDKKYAKRAPIVFLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8D8</accession>
    <name>A0AAD9D8D8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">G protein-coupled receptor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_011350</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8D8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="274"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="360"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="330"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="365"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="387"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1738056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="404" mass="45538" checksum="449BD99AA091E9C0" modified="2024-05-29" version="1">MTTLAQQKAVAIAPKITAFASILGSSTAAFLVWKRDTNKTTYHRLVLGMSIVDLIASIAWFFTTWPIPRGTPGVYGAVGNRQTCSAQAFFAQFSLSTVMYNASLAVYYVLVIVKKKTDNQIARIEPWLHANAIAWGLGTGIGGLSLEIFNQVGWDCWISAKPLGCKETWTLKEGEVGTCERGDNGSLYQWAFYYAPLWFVIVFVSLLMYWVYAHVRNQEKQMNKYAGSFDRREQQSQHERVRTQAFMYVGAFLITWLFPTLFQLVIVIGGKFPFPLLLLTATFVPIQGLLNLIVLMRPKFVRYKNKNPDTNMIAAWFRMLYLEVTGNVQPTPSRTTATSTSTPQQNNSRFDRQKTFRLTVFKPMSSSLSGTKKSGLGDTEEKSGLGDIEEEKESEDAAMEDEEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8F8</accession>
    <name>A0AAD9D8F8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_011410</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8F8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF284">
        <property type="entry name" value="EG:103B4.3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
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        <location>
            <begin position="99"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
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            <begin position="134"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
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            <end position="184"/>
        </location>
    </feature>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
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    </feature>
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        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="436"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="460"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="495"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="526"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="3">
        <location>
            <begin position="368"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1738116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="566" mass="61287" checksum="B53935E921B23255" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8Y8</accession>
    <name>A0AAD9D8Y8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011146</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8Y8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="241"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="311"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="12"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="262"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="331"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="342"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="365" mass="40970" checksum="AB3FBA153294BE9A" modified="2024-05-29" version="1">MFRSRLRQRTEEVVTEEEVEDLKQVISKLQKQLHQIVDQEIASNNEACGLATNGIVHLNIEMEGLTEERGRLLEELNRETEALEALERQCEEELDTKRKCQEDIVRLRSAMEAAKAESNTLQAEIEQSNYFQEQVDNETYYRLLADVQNLETEKERDNIRLRRLNSERQELQSVLDQLAAERDALQEIAQKSKKELQDERMTLDMYKSHHGALHEHAERLGAVGSMDNVISSFKGFFNISRAGNEPEQPTKAVVHKNQKTTDAGREKERRVSGKSTPSNISPAAAAAVGGIAYTDSVPSSDFFRKTPKIFKIGGGGGGSRSSNPDVLKSITNEEREIHISDESSAQSSITMSDDGDEVTASMTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DA03</accession>
    <name>A0AAD9DA03_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin-like-conjugating enzyme ATG10</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Autophagy-related protein 10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_009450</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DA03"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061651">
        <property type="term" value="F:Atg12 conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032446">
        <property type="term" value="P:protein modification by small protein conjugation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1460.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007135">
        <property type="entry name" value="Atg3/Atg10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14957">
        <property type="entry name" value="UBIQUITIN-LIKE-CONJUGATING ENZYME ATG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14957:SF1">
        <property type="entry name" value="UBIQUITIN-LIKE-CONJUGATING ENZYME ATG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03987">
        <property type="entry name" value="Autophagy_act_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0072">Autophagy</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1739691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="257" mass="28426" checksum="5858B48D3FA04EAC" modified="2024-05-29" version="1">MLQCCSAQSSSADANKRRPMVTHVDWDFHQSAIALVKALNQSSDGNGSGASTLSSISSPVELASWVIEANGDRIYLAHPPVLVRSNDYNSHRIDNITSGEDKIEDSFGSDVDLDESTVHNCNPRYVTEWTFSVVFHETWRVPTLYFHVHDIDGSPITRDEVVSILLSSIGGNTTAISANGSMTEEQTWDFVSQEEHPMTGKPSFFLHPCQTAAKMELLLHQPKHICPLLSWMSMILPSVGCTISPSVYHEAHKNMIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DA49</accession>
    <name>A0AAD9DA49_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DA49"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="262" mass="29374" checksum="F19A7FB4B790F92C" modified="2024-05-29" version="1">MCTPKCAMERNNYFDEDQRLGGMDSKKSAQKRQKTMMQKVIHGSMAGLVIFTAPLYALGFGLIGYKIMWRISKVIYGISRPSESILHDHFDRMQKFLETGTKEAALKSKAYMIHPTFAGLSLISSMLLAFVDPLKIEAFIPFHLLLKLNVFICIVSALAARPLTKTMCGNRNAKQWIVIQGNLSMVSAVFAVIPGTFGRLMIHLNWATLFSGGVLERLYVLSFLSQVGATNTKTYIDWYSPQIKVATLLSIPLAIASFMFYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DB33</accession>
    <name>A0AAD9DB33_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glutathione peroxidase</fullName>
            <ecNumber evidence="1">1.11.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008218</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.9" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DB33"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="70" mass="7862" checksum="2DF995D713EAC652" modified="2024-05-29" version="1">MLRTVAYRTKNTVATAMPLTSLLTKLQDASTTVLFGNDGGTDKTSFYDLVDKDMQGTKSRWRHSRVMFSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBG0</accession>
    <name>A0AAD9DBG0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007849</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22249">
        <property type="entry name" value="UDM1_RNF168_RNF169-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="456"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="559"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="618"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="700"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="756"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1111"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1236"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="311"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="581"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="625"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="715"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="734"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="756"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1135"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1248"/>
            <end position="1265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1293" mass="143609" checksum="F832346E61303D82" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBS5</accession>
    <name>A0AAD9DBS5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008015</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBS5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="171" mass="18760" checksum="E7E20CC0B990D959" modified="2024-05-29" version="1">MAASLTRLIRTLPLPLFGSAATAASFTLAKSRALPRLLGWALPAGVGALWFVWPAVDDEWKMSMGLKADPEAALKAVEEKEAKAAAKIAPVELSSEAMEKVESAYKADEVVETEADKLMAKGAATGDFTYLESQWEEFNEKAIRPGEDDDDDDDDDDEDEEEEEEEEDDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCB6</accession>
    <name>A0AAD9DCB6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Thiamine pyrophosphokinase</fullName>
            <ecNumber evidence="8">2.7.6.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_008615</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.2" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCB6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030975">
        <property type="term" value="F:thiamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004788">
        <property type="term" value="F:thiamine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006772">
        <property type="term" value="P:thiamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07995">
        <property type="entry name" value="TPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.320:FF:000001">
        <property type="entry name" value="Thiamine pyrophosphokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10240">
        <property type="entry name" value="Thiamin pyrophosphokinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.320">
        <property type="entry name" value="Thiamin pyrophosphokinase, thiamin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006282">
        <property type="entry name" value="Thi_PPkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007373">
        <property type="entry name" value="Thiamin_PyroPKinase_B1-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036371">
        <property type="entry name" value="TPK_B1-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007371">
        <property type="entry name" value="TPK_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036759">
        <property type="entry name" value="TPK_catalytic_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01378">
        <property type="entry name" value="thi_PPkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13622">
        <property type="entry name" value="THIAMIN PYROPHOSPHOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13622:SF8">
        <property type="entry name" value="THIAMIN PYROPHOSPHOKINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04265">
        <property type="entry name" value="TPK_B1_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04263">
        <property type="entry name" value="TPK_catalytic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00983">
        <property type="entry name" value="TPK_B1_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63999">
        <property type="entry name" value="Thiamin pyrophosphokinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63862">
        <property type="entry name" value="Thiamin pyrophosphokinase, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamin pyrophosphokinase thiamin-binding" evidence="7">
        <location>
            <begin position="317"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="51"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1740520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="383" mass="42170" checksum="87D6793835394F63" modified="2024-05-29" version="1">MYVPLYASTKSTGAAQSTMTVNAHRYCSYYLILLLFSNITIILSSAFSATRPSAESPSAKTIMSDQASQEERRTPITRRRYYSPFLSPLHGSNTNSAALIILNTPIKSTANSSLPDVFRVLWKSTSFHVCADGGANRLYDATIGPSSSGDDIDDNDALIPDLITGDLDSIRSDVRSYYEKKGVPIVCVEDQNYHDLDKSLMAVEKWIEKLTTTSSSSSSSLSNEDSDSNGFNQSSQAFIYGGFGGRFDQEMACINTLYSWGQKEAFQQTQMSIFDEETGVILLPEAPISNEILIRFPDIEEDDDNESREKSDQVEVGEGPTCGLIPIGARCERVYTSGLKWNLDGDMPLEFGGLVSSSNRIVDKVVTVKTSSPLLFSFEIVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCC9</accession>
    <name>A0AAD9DCC9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Lipoyl synthase, mitochondrial</fullName>
            <ecNumber evidence="9">2.8.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Lipoate synthase</fullName>
            <shortName evidence="9">LS</shortName>
            <shortName evidence="9">Lip-syn</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Lipoic acid synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_008660</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>[[Fe-S] cluster scaffold protein carrying a second [4Fe-4S](2+) cluster] + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine + 4 H(+) = [[Fe-S] cluster scaffold protein] + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + 4 Fe(3+) + 2 hydrogen sulfide + 2 5'-deoxyadenosine + 2 L-methionine + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:16585"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:14568"/>
            <dbReference type="Rhea" id="RHEA-COMP:14569"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33722"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="2.8.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="9">Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the radical SAM superfamily. Lipoyl synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.8" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCC9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016992">
        <property type="term" value="F:lipoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000036">
        <property type="entry name" value="Lipoyl synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00206">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031691">
        <property type="entry name" value="LIAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003698">
        <property type="entry name" value="Lipoyl_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00510">
        <property type="entry name" value="lipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004019">
        <property type="entry name" value="PRK05481.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009544">
        <property type="entry name" value="PRK12928.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10949">
        <property type="entry name" value="LIPOYL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10949:SF0">
        <property type="entry name" value="LIPOYL SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16881">
        <property type="entry name" value="LIAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00271">
        <property type="entry name" value="lipoyl_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01058">
        <property type="entry name" value="lipoyl_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="3 9 12" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042291436" description="Lipoyl synthase, mitochondrial" evidence="10">
        <location>
            <begin position="19"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="11">
        <location>
            <begin position="166"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="395"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1740565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="417" mass="45750" checksum="C62DAEC6D5D9054F" modified="2024-05-29" version="1">MTKNLLLPLAATAALVHSFTINNHVARGNAPIVSPSALFSTTEEATTATQQQQHTDESEISYVVARGDGSSGGGGVPMKKKKASAESTSIAINESNNNNVNDEEDDGLVRPKVGAPMPNGRPSWFHVPAPSQDVASRYQEVKESLSDLSLHTVCEEAQCPNIGECWNGGTGTIMLLGDTCTRGCMFCAVKTDQKPPEPDPFEPFKTADAVAKWGVDYIVLTSVDRDDIADGGAGHFATTVELMKHKKPELLVECLVSDFRGDEASVETLAKSGLDVYAHNVETVERLQKFVRDSRAGYWQSINTLKHAKEVKPDLYTKTSLMLGLGESDEEVIQTMKDLRSVDVDVVTFGQYLRPTENHLSVVEYVKPEKFEHFKKVGEEMGFKYVASGPLVRSSYKAGEFYLTHMINKERKEKGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCH0</accession>
    <name>A0AAD9DCH0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Chlorophyll a-b binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_008780</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated. Energy is transferred from the carotenoid and chlorophyll C (or B) to chlorophyll A and the photosynthetic reaction centers where it is used to synthesize ATP and reducing power.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fucoxanthin chlorophyll protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCH0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030076">
        <property type="term" value="C:light-harvesting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="8" id="KW-0157">Chromophore</keyword>
    <keyword evidence="7" id="KW-0437">Light-harvesting polypeptide</keyword>
    <keyword evidence="5" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042263515" evidence="9">
        <location>
            <begin position="17"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1740685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="203" mass="21707" checksum="1DEE16B2688EE671" modified="2024-05-29" version="1">MMKLAVLAAAAGSAAAFAPASNGRAATSLTAEKSKAIPFLPNPENCEGYVGNLGFDPLSISEYFPVDYLREAELKHGRMCQLAWLGYVAVDLGLRVPGYPEAMSGATSATVHDAAVEFGAMGNILVWIAIAEMTSWIGVSQMLQGSGREPGDFGFAKQYLEGKSEAQIEKIKLQEINHCRAAMLAFSGVVTQSVLFEKGFPYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDS7</accession>
    <name>A0AAD9DDS7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_006914</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048284">
        <property type="term" value="P:organelle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007033">
        <property type="term" value="P:vacuole organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006904">
        <property type="term" value="P:vesicle docking involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057308">
        <property type="entry name" value="CHCR_PEP5_VPS11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323:SF24">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23356">
        <property type="entry name" value="TPR_PEP5_VPS11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="33"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="135"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="207"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="290"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="638"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1279"/>
            <end position="1306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="140"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="153"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="171"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="227"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1742349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1386" mass="147624" checksum="3E3079DDA8057C4A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDU4</accession>
    <name>A0AAD9DDU4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005279</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDU4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="791" mass="89067" checksum="D0F352B9AA67F6F2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDU7</accession>
    <name>A0AAD9DDU7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)</fullName>
            <ecNumber evidence="2">1.2.4.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_005548</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + 3-methyl-2-oxobutanoate + H(+) = N(6)-[(R)-S(8)-2-methylpropanoyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:13457"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10497"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83142"/>
            <dbReference type="EC" id="1.2.4.4"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:13458"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.4" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDU7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003863">
        <property type="term" value="F:branched-chain 2-oxo acid dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009083">
        <property type="term" value="P:branched-chain amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007584">
        <property type="term" value="P:response to nutrient"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07036">
        <property type="entry name" value="TPP_PYR_E1-PDHc-beta_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.920:FF:000001">
        <property type="entry name" value="Pyruvate dehydrogenase E1 beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000001">
        <property type="entry name" value="Pyruvate dehydrogenase E1 beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42980:SF1">
        <property type="entry name" value="2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42980">
        <property type="entry name" value="2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="6">
        <location>
            <begin position="118"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="81"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00051764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1743951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="440" mass="48465" checksum="79766D2028CFAB9F" modified="2024-05-29" version="1" fragment="single">RLVVCNAITKRRRHCLVAHLMLNLANVLNAKMMATLLSRRYKSITLSFHNYQQHLPAIIGARSSYYSSSAAATPHYQEAAYNNNRDDDQSPPQPFPYESYNPTNPDPNYPSLGPTSKLNLFQSINSALHTSLSTDPTAILFGEDVAFGGVFRTSQNLREEFGSQRVFNTPLSENGIAGMAIGYASVGGTAIGEIQFADYIFPAIDQIVNEMAKFRYRSGNQWSCGGVTLRTPCGAVGHGGLYHSQSPEAYLCHTPGLVVVMPRGPRCAKGLLLSSIRCKDPVIFLEPKILYRSAVEEVPDADYEIPLGKAEIMQKGTDVTIVGWGAQLRRLQLACDLASKEGISCELIDLRTLLPWDSETIIRSVKKTGKLIVSHEAPITCGFGAEVAATLQQECFFHLEAPIQRVAGYDTPFPLVAEKYYLPDETKNLDAIRKVMELAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDW1</accession>
    <name>A0AAD9DDW1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nucleotide-diphospho-sugar transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005593</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDW1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005069">
        <property type="entry name" value="Nucl-diP-sugar_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052636">
        <property type="entry name" value="UDP-D-xylose:L-fucose_XylT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47032">
        <property type="entry name" value="UDP-D-XYLOSE:L-FUCOSE ALPHA-1,3-D-XYLOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47032:SF1">
        <property type="entry name" value="UDP-D-XYLOSE:L-FUCOSE ALPHA-1,3-D-XYLOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03407">
        <property type="entry name" value="Nucleotid_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleotide-diphospho-sugar transferase" evidence="2">
        <location>
            <begin position="143"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="520" mass="59319" checksum="C2A6CDD18E5D9524" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFW0</accession>
    <name>A0AAD9DFW0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFW0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042079609" description="Fe2OG dioxygenase domain-containing protein" evidence="1">
        <location>
            <begin position="34"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="352" mass="39317" checksum="C4935D278A3D3085" modified="2024-05-29" version="1">MRILSLLCCSHHDLQLDCFLLLLILSAIPNCSSFSAPNNQHPTPTTKILPVATSHEEPIILSLSDVFTHEDVNDMIQLVESSIESSALTPTSAYQEDVFSKEAWDAEDIILRNIVQPLLDDGTIPKDDSSDNEVALRSFVYAVTHHPHKITQDDIIAGANIIQRREAVERWKSDEGLSIMKLSMDYDMIKEEGDNMAVDWDEISLGKRYEVPSELLDKIEHVIPTVLKGGRDSWTRTDATIVKYHEGDLQVPHIDPCDATLLICLQPCLEGGSTCFPLLDPSRRLENSRGGGYLFFSSHAMGQDQDDSSGNERNVLSLHHGGRVLKGEKIVIQIMLEYNGDEDVQTWLEVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGE4</accession>
    <name>A0AAD9DGE4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGE4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="159" mass="17107" checksum="62C52E4DA457D092" modified="2024-05-29" version="1">MTVASYASSHLESSVITLFAACQPPMTAVLEWIWEGKGFGWKKVLGMCCVCCGMCGFTYIKRIESHHKHHRSDNVNADDLVRVSSEKSGSISRPGQTGTVRSTGMSRLFISSEFLGSQGINNNLGFQVPDLDALVSGSAQPVSVGGEDKGVDDFTSIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHC4</accession>
    <name>A0AAD9DHC4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_002721</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHC4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1746114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="310" mass="35142" checksum="FD5F2E18939FBD20" modified="2024-05-29" version="1">MEHFHGVYNYYGDDSDYSASSDEGESWLTILQRIKENDRYAQELDTDSYDYNSIDNMTDEGWEELGRDISNNTHLETVSLHEGALDNHKMRCFFRGLMKSSSINEFHLHDNELSISVVRSMVPFLQNADNLTYLDLDGNGIQTKGFNMLFRALRNRPIEKLHCDGCGIESIDIDSEHMPHNFEFLHLSGNGISTDGCRGLAKLLQGDNSTLRELWLSENEIDDEGVEILVDALQNNTSLETLNLRDNEISVEGMKACLRLVNDISSINATLQTNHTLTSLHVKEIPYVSLGINDEIQNHIDIHSEFLAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHV0</accession>
    <name>A0AAD9DHV0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHV0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052201">
        <property type="entry name" value="LRR-containing_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24111:SF0">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24111">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="230" mass="25749" checksum="D25BC6C3121F4990" modified="2024-05-29" version="1">MMDLEMMNLEYASSEDLIFDLQHAEFIDHFLVKGSYRRLHNMSNEDWERLGRAMAANVQLKFLALNELVLDRPDQIVSSFFRGLTGSNTVLVLELNNNGFGIDGARSMVPFLRNANELRRFDIDDNDITSEGFHALWSALTESPITALSCSTCLLDTIEINIESIPNRLSSLALGDNSINSDGCRELAKLLLRENAALKSLFLDGNDIDNDGAEILADALQNNTYWNVSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DI41</accession>
    <name>A0AAD9DI41_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DI41"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="126" mass="14555" checksum="1AB38C9FBD5DF169" modified="2024-05-29" version="1">MSSNNELDDIVREVIEENPPEEQGIRPEWQNHVGWHRKENIFNLRGREDKEDATPKELPRNHEVNTESNEALHGIQEVHTLNTTTFLSSASLITVLIICIICVRKYYSKTNMSCSIKPRKTEAELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJY7</accession>
    <name>A0AAD9DJY7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cupin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_000454</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJY7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050910">
        <property type="entry name" value="JMJD6_ArgDemeth/LysHydrox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480">
        <property type="entry name" value="ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480:SF35">
        <property type="entry name" value="TRANSCRIPTION FACTOR JUMONJI, JMJC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042152485" evidence="2">
        <location>
            <begin position="28"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="JmjC" evidence="3">
        <location>
            <begin position="187"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1748515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="435" mass="49908" checksum="2BD17C80B344EA6F" modified="2024-05-29" version="1">MNFSYGRGYKQASFLSTLSLLASFSAALNSETTCIGCPLNADENSPYSKYKHWEDAPASWEEYGHDNDESVCGVPRLTVQQWEKGKWWQKNKPVIVMNVTEQWPAVEHWKKEEMLKRYFDAEATMGEARLLGETGPDDAGHTLTPTTVGTFITQHMYDPLKYFFDRKLRAPQGMLDDCHPYPQPTRAYLKDEMAYAIEAPSHKRKVDPRDDIWRDHLAISIGKDLTGLSFHHHGPAWNVVIFGAKRWILWDHNRFKNNMTRQLRIVRPLDDAELEDRVPPSDVRSHVLSSPEWIKYLYPSPERQEEIRAHGHDCIQRAGELMFVPRRWMHSVINIGDTVSVISEVGHVKGEGKAEEDFAYDPYESSDDDEEDHNEEGLSTEEKIRRRGPPPQWLCADQNPNHPACIFCAKNPDNPVCGDGFIDEDSSSSDDSFDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XS05</accession>
    <name>A0AAD8XS05_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sel1 repeat family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016797</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000065">
        <property type="protein sequence ID" value="KAK1732514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XS05"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="180" mass="20001" checksum="6320536377B35F01" modified="2024-05-29" version="1">MGNTKPTCPYCRTPIPETQAEADRNSMKRAEANDPVAMRQMGANCAFNEGDYSAAFEYWTKAAKLGDVEAHNQLSIMYLNGSGVDKDEQKGIYHLEVVAIGGHPEARYHLAMQEGRNRKIDRSVKHLIIVANLGHDKSIQKLMLAYKAGRVDKEEFAAALCSHHAAMVAMKSPQREAARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTB8</accession>
    <name>A0AAD8XTB8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mitochondrial carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_016361</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000055">
        <property type="protein sequence ID" value="KAK1733030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTB8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000064">
        <property type="term" value="F:L-ornithine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990575">
        <property type="term" value="P:mitochondrial L-ornithine transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF58">
        <property type="entry name" value="CARRIER PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="4"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1733030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="268" mass="29826" checksum="F79C4BA8A7ED87B6" modified="2024-05-29" version="1">MINGISIESFIAGFAYGGTTVLVGQPLETLKTLTQVSTTTSPNMLTTAKQLYSTSGIRGFYRGGTPLLLGGGLMRSAQFGFYQSVLPVLDDKFGKRDPQTYWLGCINPHVVAAGWAGGIGRGLVEGPFEMVKVRRQIVSDWKFADVTKGFGVTVFRNSFLFSSFVIYMDVLKQQLARYDMTLSPFFTAGICSNLAWLTVWPFDVVKTKKQSGKFEGRSVMWLLRDTVRTGDMYRGLSVGLVRSFFANGISMEVYTRVEKELKIVFNDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVN7</accession>
    <name>A0AAD8XVN7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase</fullName>
            <ecNumber evidence="5">3.1.3.46</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_014597</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.46" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVN7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003873">
        <property type="term" value="F:6-phosphofructo-2-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004331">
        <property type="term" value="F:fructose-2,6-bisphosphate 2-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006003">
        <property type="term" value="P:fructose 2,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006000">
        <property type="term" value="P:fructose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000644">
        <property type="entry name" value="GpmB, Fructose-2,6-bisphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003094">
        <property type="entry name" value="6Pfruct_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013079">
        <property type="entry name" value="6Phosfructo_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606:SF44">
        <property type="entry name" value="6-PHOSPHOFRUCTO 2-KINASE_FRUCTOSE 2,6-BISPHOSPHATASE LONG FORM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606">
        <property type="entry name" value="6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01591">
        <property type="entry name" value="6PF2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000709">
        <property type="entry name" value="6PFK_2-Ptase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00991">
        <property type="entry name" value="6PFRUCTKNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphofructo-2-kinase" evidence="4">
        <location>
            <begin position="31"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="478"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="488"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1734724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="516" mass="59009" checksum="2A2E865EBF03D6AC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVX8</accession>
    <name>A0AAD8XVX8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014932</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVX8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052228">
        <property type="entry name" value="Sec_Metab_Biosynth_Oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47534:SF3">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE-LIKE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47534">
        <property type="entry name" value="YALI0E05731P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="353" mass="38473" checksum="9016A54A6F0E5A16" modified="2024-05-29" version="1">MMTPSWKVFIAIGIAISIRPLVTTLIWLKHAPADDFIGKIPLLSTEDLMTHVKGKNALLIGGTRGVGMGTALALYRAGAHVTIVGRSDHSGAKAIASIQQLSPSTPTSTPGTINFVQGDIGTICTTMKLIEQLSASPKSYDFAVVSAATFPDWTKPLQNDDGLDKSFAIAVVGRFLVYRNAHLFMNRHARIVNVLAAGEKLPIDLFDREIASGERDVTGLFEAMITFAIGNEIMMDGLYTHDDHFASKYYFTMVSTHPGLLKTDLHRGQGFLFDMLETAMVSIAGTTEEEVGVLQSSILVSKQLHLNGLSFVDSFGYGRVHDVKTKSFIEENSSWLWKMLSKLEKSSAKCSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW89</accession>
    <name>A0AAD8XW89_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_014622</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XW89"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="138"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="172"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="208"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1734749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="249" mass="27266" checksum="31E5B55A0A3E78A2" modified="2024-05-29" version="1">MPGKTTELSLSGGSGKREGLLPPHKLSAMYEETTEATKSPTTTIRLLACANGVGLTISSIMTAVLSVLNNQISILDIVVIIISAWVGIFALFLESKLALVHTIRSTITHGVPICGHVTLRGGIYTIAGLLNFAILEPLHIVVGLFSTGVGIYMIKIGKKAGEHLVTLRTSITDEKALLKAFMRHDENGDGYLQQEEFESLMLSLGVELDRDELDAIFFTIDVDNDKNIVYDEFRSWWKQTTSETRVTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWR2</accession>
    <name>A0AAD8XWR2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Serine/threonine-protein kinase</fullName>
            <ecNumber evidence="8">2.7.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_014604</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWR2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345:SF91">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE PLK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="181"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="94"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="101"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="129"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="142"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="158"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1734731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="550" mass="62142" checksum="658370B908FFF446" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWS2</accession>
    <name>A0AAD8XWS2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA/rRNA methyltransferase SpoU type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014313</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWS2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.70.10">
        <property type="entry name" value="Transcription termination factor 3, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038538">
        <property type="entry name" value="MTERF_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041942183" description="tRNA/rRNA methyltransferase SpoU type domain-containing protein" evidence="2">
        <location>
            <begin position="30"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="333" mass="37143" checksum="5F973F66EFF419EE" modified="2024-05-29" version="1">MISRLALTLLVVLPSIIIILPSAHPLTSAAFCSTCCYSHRRTSPHYRITLLHSSSSSADNDIVDPSNDIDGYLALQRRLHLTPDEANLIRNRIGGITPRKKLQNCNNAIDDNVTAGKEQPTMERNLAYLEEHLGMTMEQLRRIVVGYPLVLKMKEANLMSAVEFFANALWYDVDGGDDVDCSHTSISYDLQEDYKKGWQHFYLLEYNVEKRLKPRLERLRIAKENQAKEVGSAAAAGVDEEMLRSIATLTESRFETWLLQINGTKSDGNNEATTKATQLVSPPPQRQPSNSPSAYVILSNLQSGGNIGNIVRSASIFGCEECIVVGQKRYNTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XX13</accession>
    <name>A0AAD8XX13_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">anthranilate phosphoribosyltransferase</fullName>
            <ecNumber evidence="2">2.4.2.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_013652</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 2/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the anthranilate phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.18" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XX13"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004048">
        <property type="term" value="F:anthranilate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1030.10:FF:000002">
        <property type="entry name" value="Anthranilate phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="entry name" value="Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.970.10">
        <property type="entry name" value="Transferase, Pyrimidine Nucleoside Phosphorylase, Chain C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00211">
        <property type="entry name" value="TrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005940">
        <property type="entry name" value="Anthranilate_Pribosyl_Tfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000312">
        <property type="entry name" value="Glycosyl_Trfase_fam3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017459">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036320">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01245">
        <property type="entry name" value="trpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43285">
        <property type="entry name" value="ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43285:SF2">
        <property type="entry name" value="ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02885">
        <property type="entry name" value="Glycos_trans_3N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47648">
        <property type="entry name" value="Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="4 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Glycosyl transferase family 3 N-terminal" evidence="10">
        <location>
            <begin position="4"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 3" evidence="9">
        <location>
            <begin position="76"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00061500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1735489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="356" mass="37883" checksum="0BF746FFC2988090" modified="2024-05-29" version="1">MSLKPYIETLIIGDRHLTADEACDAFSVILTKDPPPCQVASLLTLLRARKETPQEIAGMVRAMNNACHAVKFSDNRKLLDIVGTGGDGADTINISTASVVLAAACGATVAKAGNRSVSSACGSADVLEMLEVQVDLNPTQVIECVDECGIAFLFAPVNHPAMKAVAPIRKQLGVRTCFNILGPMTNAASAQHAVIGVFHEDLLELMADTLKEVGRVDHAVVIHGVGLDEISPLGPATIVEIKNTAPVGEKKVYDTKIHKFDPLSVNIQRCKVEDLKGGDPAQNAKEFELVLEGGDYETNAKKDAIVLNAGVGCYVYGLTETIEEGCALARKTLVEGKATEVLKKWKQVSKEIAARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXW2</accession>
    <name>A0AAD8XXW2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013623</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXW2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="191" mass="21097" checksum="8359F1B6C7FB049D" modified="2024-05-29" version="1">MHDSWNTSMSSLVNSSFLSSSNSSALVTNPPIVNTSQRQEYSTSTRTKKNIQDNIDWSTLNNYSIEEREEPPCPNFPVPEGDDSSSSAPLDDSEYSHVRRRSVFEIDVNFDEDQEAKATSPGADGCNPAEVPPPPHKKNRRSSLRLGTEGRSYEPTNPLLPTNDAPATPASCSSNTALTSMFRIMRIHHLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYC9</accession>
    <name>A0AAD8XYC9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PhyH family protein</fullName>
            <ecNumber evidence="5">1.14.11.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_013282</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.18" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYC9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048244">
        <property type="term" value="F:phytanoyl-CoA dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47567">
        <property type="entry name" value="MITOCHONDRIAL SUBSTRATE/SOLUTE CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47567:SF1">
        <property type="entry name" value="NAD-DEPENDENT EPIMERASE_DEHYDRATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0812">Transmembrane</keyword>
    <feature type="repeat" description="Solcar" evidence="4">
        <location>
            <begin position="447"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1736146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="624" mass="69547" checksum="559E18BC5D74CE14" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZB7</accession>
    <name>A0AAD8XZB7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013187</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="25"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="269"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="878"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1024"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1089"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1191"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1452"/>
            <end position="1487"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1274"/>
            <end position="1320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="300"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="315"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1036"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1108"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1204"/>
            <end position="1216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1452"/>
            <end position="1462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1533" mass="173764" checksum="1DE0C073EE1B771B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZL6</accession>
    <name>A0AAD8XZL6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZL6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042291822" evidence="1">
        <location>
            <begin position="21"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="173" mass="19794" checksum="2B17B931B83F69A6" modified="2024-05-29" version="1">MSRYTSRAILLAAAMATASAFAPSGVTSRISSELHLDNHIADMIDHEVDRLQNIGLWRQKEAEKHKKWAEMEPSLPKGFDFNTVTEFQPNSDAAKKIQMRKDRRMARDDPMRYCADRCVSTGNCQVWEDMFDLSAKEVMAFCEECVLSEEEEPCDVPEKFLDNAGKNSWELRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZY7</accession>
    <name>A0AAD8XZY7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012985</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZY7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042042730" evidence="2">
        <location>
            <begin position="25"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="298" mass="33255" checksum="2B3ED6E670714E3D" modified="2024-05-29" version="1">MKLPSAATILLLSLTSSISTTTDAFRATPSSSGRRSSNQQQQQQNHLPKNPLKIESISKLEVTNRLGLKTDPKTGAVSIGSDPNQVYNLHNEHEVICPITETHQGVLTTYTEFNDDYDDNEEYPASTMANNHELVSQAILSGSLAASIRNRCKDGNSLYYLPSVVTLVESLAEDVEACLFDAIPNMGEMMFNAEGLETNEILMDLTDMNDDAATTTEEGEEARRHLILFARNTHFDPTSATSDVYLLPSNKRREGKVWKFSIEYKVATINLRQIKSFGVRDSTTPLRPDVWLKDDCYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZZ1</accession>
    <name>A0AAD8XZZ1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZZ1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1736759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="258" mass="29175" checksum="7F8C97472077B8F8" modified="2024-05-29" version="1">MEPRTAMEKELLKESLYKNRVQEILRKHKGFLSSSYNEDVANEGDDIELLKKQYSSERKIIDGIISNERSAFLSGLALSGVVFASVRFGPRYLAVKLGGIEKARALKEADDAARKAGTRWIQQGVSFLFEASFGAWAGYRGYNMISSQNSNSYDEIAKIPLCAGKSIVSEKICSEWVDLVHNEMSKDFWKNLDEEDCRLKDKGRWKAVLGFADNCIKRKAFEDSYRKQHGMKSDDPVDVPKGGVPTDILQMLRKQRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y004</accession>
    <name>A0AAD8Y004_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidase A2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_012491</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DDI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1737046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y004"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05483">
        <property type="entry name" value="retropepsin_like_bacteria"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034122">
        <property type="entry name" value="Retropepsin-like_bacterial"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12917">
        <property type="entry name" value="ASPARTYL PROTEASE DDI-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12917:SF1">
        <property type="entry name" value="AT13091P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13650">
        <property type="entry name" value="Asp_protease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041947018" description="Peptidase A2 domain-containing protein" evidence="5">
        <location>
            <begin position="25"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1737046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="364" mass="38587" checksum="6702D013BE78394B" modified="2024-05-29" version="1">MVKTISHYLNCFVLLSAASSSVTAFLVQHGAYNVAKPLRSSESVDETEPVSVIGVVAPLTYVGPYACLGLNFPNIERKPGFEINFVLDTAANVNTISSEIASELDLPVLIKGEDLSILGSAGAGGSFQAGDIVLLGDSRLSGMPESQQNNTFMTNMTAAAMNLGIANAVGGGMLGISFFDCFKGGVEFDWYGTDGDPPTLQFYYDSLPENAKENASCISLDTEDFFGVATVSVKINGKALRAIIDTGAPITIISPAVADELGISKKDGTVKIKGIDDGDAMGVSKSLDEVTLSIGDVNINLDTIFIGELPGLAMASNLVPECRQPQVLLGLDALRRTYRMILILSKAEVWLEGRQRKITNNSVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y030</accession>
    <name>A0AAD8Y030_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_012607</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y030"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042095066" description="Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase" evidence="3">
        <location>
            <begin position="316"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1736585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="393" mass="42857" checksum="378E0BD42C3667AE" modified="2024-05-29" version="1" fragment="single">MMIPTLLLAACTATNVEGFAYSPLSLRPIVAGGPEATSTSIHMGKRKPSMKERRRQRAKKLPSATVDRGILNELPSVDTWEKTDASVGSKRESIPTSEVAEEDNAAITDEETSIDEETEETFAKASSLVQAQRKSVGCLTHVRKRVEESFPINEAAKGLAEKGYFVYDGFLSKAVDADSENEDAVFGDEMVSEMLSESSSMLSNDKMQRDITRIADGEFVAQIVGGENYVLCPRITEYVVSITRHLPPLLNKEYDVIGAGDLPKLDSAASMGSLRLYDRKTKLGTLSFLANPEDAASDDSVSERPFGVVCGDSDGTENDSRRLTAILYLSSKEWDSSNGGGLTMETDGQKVEAIRDRIVLLRSDVCSHRHEPWLGSDDSGLDQASCAIVHFIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y064</accession>
    <name>A0AAD8Y064_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012397</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y064"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="286" mass="32174" checksum="761873789CA4967A" modified="2024-05-29" version="1">MTMTIASQEAVEETAKQRQEDSDMERNNVELNENVSSIVSNPNEIKKQIIKGVVRAKLNKRRHLVIPGAISPTYLDYLMPSIVADLFQPQTVTYNGGVANIKQWKISCYLEVMESGIPCTNPHEGLKSHCRELLDTCNTLFASWYRQQHACNDKTTSSYKVDEEGNPIVSRLMTFITRYTPAPDENALLKHVDGAGKVDGSVVVALPIDRWTASEEENSFEGYGGGLTFWDGRTKRSANGTRGPEEIVYDTRSGDIAFIDRAVWHQANPITRGTRWALVIFYKVER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0B9</accession>
    <name>A0AAD8Y0B9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aldo-keto reductase family protein</fullName>
            <ecNumber evidence="5">1.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_012487</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1737042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0B9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19136">
        <property type="entry name" value="AKR_DrGR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF3">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00063">
        <property type="entry name" value="ALDOKETO_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="53"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1737042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="374" mass="42175" checksum="BA250A9F1AD58F21" modified="2024-05-29" version="1">MGKMGFQGVVSRAIDARGLLDCAALTPLHHPSSELIFNNNANDDNCVLMPWVGFGTYRLGKRQSRTATLEALKSGYRQIDTAFIYGGQTTELEVGKTLQDALQMGVIQSREDVFITTKQWREYHGYDASMKCLELSLERLGVDYVDMWMMHWPGPCFESRDKRQTVSSENAAAEDDPWLHAKEGMGVNEIATLRADTWRAMEDAYRRGKTRSIAVSNFTIKHLETLKETATLWPPAVNQIESHPYYPQNDLIDYCQKEGIVVQAYAALGGQDGTKAKWKALGGKLFESAPVLEASERLHKTPAQILLRWSLQRNCAIVPKTCDPDRMKENSDIFDFELSEEEMKAIANLSEGVGDGEGRLCWRTEKLRMLDIIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0M5</accession>
    <name>A0AAD8Y0M5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamine amidotransferase, class-I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0M5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044992">
        <property type="entry name" value="ChyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE YLR126C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695:SF5">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE YLR126C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="1">
        <location>
            <begin position="114"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="370" mass="40821" checksum="78438D33F3A23D7E" modified="2024-05-29" version="1">MTSKDRIIVSKTVLLPNSTSCSADDGADASMCHSADSSKSKSLNLMMISCEENPPYGPSKDTAIMFLELLCQAYERKCSLLSTTVSEMSREQQMANNGGDTILTISITVYHAQSKNDYPLTSSEWSSYDGVLIPGSLSAAYDTHIEWIEKLQSVIRNDIHKMRLKTMGVCFGHQCFAHAFGTHGEDGGREGRAIKCPTGAKAGKISLSFTQFGQLLLLDGNSDKSNMEMLYTHGDMVHSLPEFAISLGGNANVPIEACAYFSSKEEKILFQKQQQRQTTMPTNANGDDNKTETSTTVRPYAFTFQAHPEYISPTGFNVNYLNTVKVMEDRGYITQQLLEEVCEDARVNFEKVQGDSLDAMIAVATTFGWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0X8</accession>
    <name>A0AAD8Y0X8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">V-type proton ATPase subunit H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_012000</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the V-ATPase H subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0X8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004908">
        <property type="entry name" value="ATPase_V1-cplx_hsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011987">
        <property type="entry name" value="ATPase_V1-cplx_hsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10698">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10698:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11698">
        <property type="entry name" value="V-ATPase_H_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03224">
        <property type="entry name" value="V-ATPase_H_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="461"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="490"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="532"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="600"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="632"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="856"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="894"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="929"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="958"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="9">
        <location>
            <begin position="313"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="12">
        <location>
            <begin position="728"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="12">
        <location>
            <begin position="764"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="694"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="803"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="700"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="830"/>
            <end position="842"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1737133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="981" mass="107496" checksum="27E25411B41D3743" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1K7</accession>
    <name>A0AAD8Y1K7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012017</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1K7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="338" mass="37051" checksum="EF0381509E0A8E7F" modified="2024-05-29" version="1">MHHLLFYSHATAAAERLISSGSSRSFLHNTYKRNIHASHKTHQAAAGKRNKDLFTPSPFKRSDKINIDDKFTVQRDLREGDNTYGIRRYLLLPRTNDNDDPTLKPNIIASINANKNILFGAQLHAKQSGSDEDYIADYFAACEPLLDIAKEDASINGQQVQALAALNGLCSWVTACLDRDGEGSEVLTSLLHGEQPNTLLDNDKEEQVENRGASGSSNRRARQNVKSQSAKIILNNESDRILMLDAIRAIATGIPRPGHSVVGQGTYRDGAEGWKSLAWEYSNLATVPVDASNGVTGLEEVSLYKSRDGEVAKIEHLASVEAGYLKIAGGAMARMFFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1S7</accession>
    <name>A0AAD8Y1S7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_012122</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1S7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000041">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase ERECTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000095">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase GSO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050994">
        <property type="entry name" value="At_inactive_RLKs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48010">
        <property type="entry name" value="OS05G0588300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48010:SF58">
        <property type="entry name" value="RECEPTOR PROTEIN KINASE-LIKE PROTEIN ZAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="91"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1737255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="764" mass="85008" checksum="183A43D5775633CE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2J0</accession>
    <name>A0AAD8Y2J0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PA14 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_011614</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2J0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.182.10">
        <property type="entry name" value="Toxin - Anthrax Protective Antigen,domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148">
        <property type="entry name" value="KERATINOCYTE PROLINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148:SF3">
        <property type="entry name" value="KERATINOCYTE PROLINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56988">
        <property type="entry name" value="Anthrax protective antigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042114837" description="PA14 domain-containing protein" evidence="2">
        <location>
            <begin position="27"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="domain" description="PA14" evidence="3">
        <location>
            <begin position="31"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="658"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="988"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="196"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="665"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="684"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="988"/>
            <end position="1082"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1737842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1229" mass="128162" checksum="37221CDADA01C673" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2T1</accession>
    <name>A0AAD8Y2T1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Leucine-rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_010621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2T1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1738591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="257" mass="29595" checksum="37E32DCDC6350F0D" modified="2024-05-29" version="1">MVSDELLKSAGRHFGGCENLESVEFGDKLETIERYAFKGCISIKHLKLPSVITIELQAFCNCKALIDIELSERLETIETRAFIGCERLQRIVIPLKRNLFSIDRLLHLDRLRRKYKQFDGCDQLKTVDLVGGAHIKTVASLHMESWRSEMIAEINRINQVLLNATADYKAEAIRQWMESVIDKMDRYKAEHYRYVEEGITLLELALWKAKLGEKEEKAVEERAKQAKVDTASARKDRRITCGADIVIKNVLPFLELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2024-10-02" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y466</accession>
    <name>A0AAD8Y466_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SET domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_009796</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016872">
        <property type="term" value="F:intramolecular lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.70.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016087">
        <property type="entry name" value="Chalcone_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016088">
        <property type="entry name" value="Chalcone_isomerase_3-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036298">
        <property type="entry name" value="Chalcone_isomerase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47698">
        <property type="entry name" value="FATTY-ACID-BINDING PROTEIN 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47698:SF2">
        <property type="entry name" value="FATTY-ACID-BINDING PROTEIN 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16036">
        <property type="entry name" value="Chalcone_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54626">
        <property type="entry name" value="Chalcone isomerase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042247629" evidence="2">
        <location>
            <begin position="31"/>
            <end position="1329"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="3">
        <location>
            <begin position="133"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1095"/>
            <end position="1124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1739253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1329" mass="143080" checksum="0580D8A3EDDE9578" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y495</accession>
    <name>A0AAD8Y495_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009944</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y495"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1739401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="255" mass="28748" checksum="36DC9358E1A9869F" modified="2024-05-29" version="1">MRRFQSDEIKNKSLNQRIRRAAAAARGGQKPSSIVVDPSMMSFVSTVTATPPLKTKLKAKKVRYSSAAAQQMRKNKVVDKEKKKQATKYATQLYADSKMPGEKNLSAKKVQEIVEKKLGVSVSKRTINKHFAEGRVGTSPKKTGPEGNFDDETVLNLSNAMESYIQIQQLNGGSGDVTYKKLEELLKQCTAKKKACDCAWLLRRLLEESGADINAGRSNNAEQRRIMWTTYYNLKSWFDNWEKDLLKLGFSNTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5I0</accession>
    <name>A0AAD8Y5I0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010472</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5I0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="211" mass="23419" checksum="566548E7B84F4F95" modified="2024-05-29" version="1">MSNTKDTTEQETSSSSRHKGMTTSTAKIEPKRQFTNSRRERPRKLRVFSDELPRSKDLYEADIDSFVSTCAPGLSFGKNYDGNDATDGDMLSPRASSIHKRSLPSLSFLATTTIAAEKKKLKIEEEKRKEVIAEMEARKALALNPLHSSDDVGKTKGDRPSCVNHLSSELQSATVIDNTKSNVTMPPLLKQFLYPLSKGGEKRDGDNNEQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y631</accession>
    <name>A0AAD8Y631_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MATH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009853</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y631"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14733">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00121">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045005">
        <property type="entry name" value="BPM1-6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002083">
        <property type="entry name" value="MATH/TRAF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR26379">
        <property type="entry name" value="BTB/POZ AND MATH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR26379:SF187">
        <property type="entry name" value="OS07G0655300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22486">
        <property type="entry name" value="MATH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50144">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MATH" evidence="1">
        <location>
            <begin position="26"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="SAP" evidence="2">
        <location>
            <begin position="379"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="423" mass="47021" checksum="24CC57728F14B163" modified="2024-05-29" version="1">MPLLHPRIHTTIDVGNPPSSPDESRYKSIQIHFHGFAYLPHARGRGIISPRFSMNGHQWELGVYPGGELHARHTPRSSTYLAIYIRLCSQGSVTASFDVKLLNKFGDLACRMRSPAINWRSDMITEWSWPQVMRRSKVLDENRYILDDDGTLAIVVSTKEDATAAFVPKNPLTKMMKGMFNDETTADVCFEVCSAEGKDDDDDGTKRAKTSTSFYAHRSILCGCAPMLAALFDVEDTVMSNLISFNTCSAMCMGGSVPKEELMTHAKDIINAADKYSIVNLKLEAEAVYLNSTIFTVDNAMDNLLYADAKNCALLKETVLDFLAENSKEAINNISFADFPGSVVKDLMIAFDRSKKRILQEHCSDSEGEDNDDDDGEDYSLMRVSELRRKLDGKGLDVDGSREAMIEALKNSTALSYAHDATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6N9</accession>
    <name>A0AAD8Y6N9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Diacylglycerol kinase</fullName>
            <shortName evidence="6">DAG kinase</shortName>
            <ecNumber evidence="6">2.7.1.107</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_008728</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10272"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.107"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the eukaryotic diacylglycerol kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.107" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6N9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004143">
        <property type="term" value="F:ATP-dependent diacylglycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007200">
        <property type="term" value="P:phospholipase C-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037607">
        <property type="entry name" value="DGK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000756">
        <property type="entry name" value="Diacylglycerol_kin_accessory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11255">
        <property type="entry name" value="DIACYLGLYCEROL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11255:SF80">
        <property type="entry name" value="EYE-SPECIFIC DIACYLGLYCEROL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00609">
        <property type="entry name" value="DAGK_acc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00045">
        <property type="entry name" value="DAGKa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="8">
        <location>
            <begin position="139"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="105"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1740633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="559" mass="61865" checksum="F9B3A4085C4E4950" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6U4</accession>
    <name>A0AAD8Y6U4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-CH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_009057</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6U4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-CH-type" evidence="5">
        <location>
            <begin position="26"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1740107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="460" mass="50181" checksum="F5528BC5FAF3FC4F" modified="2024-05-29" version="1">MSSTTNSKKRTAADAGLPDDNGAAVSNEDTTPCCWICLEEGLDDSGAPLVRDCSCRGSSGFAHLPCIIQYAESTLRNAQERGGAVQCSDICRGFLTCPNCNQEYQNNVKYEMTRALVACVEREVTGTGHGQELLHATALTERLFQLDGNKEGDKAEGDEIYGKLLALMDKMKDCDDISESFKAIELDIYASMCNFDFTVGTDDSLKTAEANIAKVRDICSAAGGDQMHLLTYLDAMMKDIESKLSGKDLQCEHVKDLNFSRQHYIDAVETLGQSDPTTIRSGVDLAAALYREDCTIEATRLLLKLVKIGRQVHGPDHNCTANVVLALTKVEERRVIVKSQKRWFKALRYEDDGSDCVLEGLLPESADDPKVEESGTIPILPGKGAAVIPSTDILPFPGTPVICHGLRLRGSSHLNGKIGDVRSLDVDDGKCLVHFEEEGLEPTVVKIGNLRVLFELPEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6Y4</accession>
    <name>A0AAD8Y6Y4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009504</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6Y4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1739745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="147" mass="16116" checksum="4C42A898D2030889" modified="2024-05-29" version="1">MNSPNDLQQSPSLPVDFESVAKKLQASRKRKEKHVDVSQNIRSGEVVMANKELELKWLMAEGGGIVNDPHQPNHGSSIPTTNKGKVPLQTAHMQEGPANAHVRHELAAIAVMEVIDLTDANPEGAKQQIMIKREVELIDLTLSDEDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6Y6</accession>
    <name>A0AAD8Y6Y6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha-(1,6)-fucosyltransferase</fullName>
            <ecNumber evidence="2">2.4.1.68</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008863</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.68" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6Y6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008424">
        <property type="term" value="F:glycoprotein 6-alpha-L-fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13132">
        <property type="entry name" value="ALPHA- 1,6 -FUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13132:SF29">
        <property type="entry name" value="ALPHA-(1,6)-FUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="460" mass="51367" checksum="A291F81E0876F6FF" modified="2024-05-29" version="1">MVASLQHRRYEPKAASARQWQNPVLISIGALILITLTNYISIAKYVNQNEKKALLTSNNNLPASSSSTARLLRKANSLTSYWWPSQDDGGLMAKIYNVQHPADCSSPSTKFFVLRSLMKNERDTRGLTAFAHAASSHLLHALTDGDKFKKFGSRILITDDVMWPMAKNCANGPETRECYFEPLTNCKLSDVDPMNTSNSSAFLKDSSDEYDRSIRTLYSARKKWFRLTGQKYSWTGLGGGDIDHSTIFMLAATLAYYLRPNPYIREQIDKRLRQSLPADIDPDRTIGVPIRRSDKCYGHTLEGSARGELDCPALDVYLSGVKQFVDFDPLVENVIVTSEDKAACDEFVELVKKELPQLRIILNVGDVQQGTGSGSMLEAYVDQASNEDVVVSALTSMHMHLRARYFVITSLSTWTSTIAVMARVYGFASEVYVHDVGRNRNLFAALARKGCEPLTGERGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7M3</accession>
    <name>A0AAD8Y7M3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nudix hydrolase</fullName>
            <ecNumber evidence="5">3.6.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_008574</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7M3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12629">
        <property type="entry name" value="DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12629:SF0">
        <property type="entry name" value="DIPHOSPHOINOSITOL-POLYPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="4">
        <location>
            <begin position="242"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="322"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="324"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1740479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="464" mass="49779" checksum="019806D136AD12D9" modified="2024-05-29" version="1">MTPTCQGRIKAPPICSAPALQKVASDVSELTDNKICFSLEEAESCAVKARFLWNNGVYAHSLQQQHQQHLHGVGGDACDGNEVPLNIDGIGEYWKIHAESAAAAAEVKAYVSSSSTVVTNTSASSMSMCGGGGRGEGSVMGTVASSASVAGGGSTSTPIMKKDRPPLEVVRTDNEDSLVVHSEDEHNPHPAAATSNVAAATCHSSSVLPLSRDFTDNLVKGNSSRQGRSLQRWLVHSQTEELVRQVAGTVPITRDGRIVLVSASRKSEWILPKGGWDADETREECAARETYEEAGLLGRLGACLDPIDYETSKAKKRRLNMMLGEGGGESGGAGGEVSRPPLPKRIKKVGEGGSSYSPTGPELTEEGTGKSRSKNASGSSPKKKSSNSDAKNYSYVRLLLFPLYVSEVKNVWPEKGRLRKLVDIDEAIKIMEKEDRGYFKRGLEMIKDRGLHLLKPDSLEDNVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7U3</accession>
    <name>A0AAD8Y7U3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Glycosyltransferase (Family 49)</fullName>
            <ecNumber evidence="9">2.4.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_008694</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.-.-" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7U3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015020">
        <property type="term" value="F:glucuronosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042285">
        <property type="term" value="F:xylosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051292">
        <property type="entry name" value="Xyl/GlcA_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12270:SF52">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-LIKE PROTEIN GNT13-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12270">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13896">
        <property type="entry name" value="Glyco_transf_49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1740599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="645" mass="73365" checksum="E99BEBCDD422EDDB" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9P2</accession>
    <name>A0AAD8Y9P2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Polysaccharide pyruvyl transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9P2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007345">
        <property type="entry name" value="Polysacch_pyruvyl_Trfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04230">
        <property type="entry name" value="PS_pyruv_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Polysaccharide pyruvyl transferase" evidence="1">
        <location>
            <begin position="23"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="200" mass="22403" checksum="BE635B96AA36F3A0" modified="2024-05-29" version="1">MVKEGDHVWGICVNPSHFRAGTLPKSLTLHSVRGPLTSNFIKKEGFNSTKNDSLPLGDPVCFVVHKNDLGHTFVRKPPPNVHIITCAQHWETAVTEIQSCGFVASSSLHGIVVADALSIPRLWFQFNDTSTIRTEGNFKYQDYLQSIGHMNARPIRNVTFIEDTTKYSNVLTNPLVLTQSELQAIINQTSDSFPYHLFHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAB4</accession>
    <name>A0AAD8YAB4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chitin-binding type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_007249</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAB4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21113">
        <property type="entry name" value="AGAP001705-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21113:SF4">
        <property type="entry name" value="CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042024035" description="Chitin-binding type-2 domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="3">
        <location>
            <begin position="34"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1741676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="543" mass="60408" checksum="747287C06434276F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAF8</accession>
    <name>A0AAD8YAF8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007163</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAF8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="115" mass="13329" checksum="AAB2C8C0C6F877F9" modified="2024-05-29" version="1">MSGARMIKLPGYLYDQSDEQYDIDTFEQRDGKNAPSGTKLAHYVNDRASEWKSLPTTKKVHRMRRAIDRRFDGTPERRTRDYHLHDSDDDDDSYGRGYGYGGEGYGRAQRDCIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBL3</accession>
    <name>A0AAD8YBL3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA-directed RNA polymerase</fullName>
            <ecNumber evidence="3">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_006090</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 17">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBL3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02736">
        <property type="entry name" value="RNAP_III_Rpc1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.390:FF:000004">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035698">
        <property type="entry name" value="RNAP_III_Rpc1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015700">
        <property type="entry name" value="RPC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48446">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' N-TERMINAL SECTION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48446:SF1">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' N-TERMINAL SECTION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 15" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 15" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase Rpb1" evidence="14">
        <location>
            <begin position="50"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb1" evidence="13">
        <location>
            <begin position="163"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF05000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1743469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="715" mass="79254" checksum="EFEBD39410E57C7F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCX7</accession>
    <name>A0AAD8YCX7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006357</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCX7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="216" mass="23017" checksum="F37EED0CA89EC59C" modified="2024-05-29" version="1">MKCVMYIISAAAVSATPLLRRNHRSLAETTNYADGTNFLQTLGIEEPTVENYGYKSTADVRAGSCHDNTEPSCRNKDEDGICQGPFTTDGSIRTIAYAAVAQSDKDEGSFTQTYCARADVYADVFDTGYESSVAHAKANLVITFTIKDDEHEVTSFEVEHLNAQGGGGLSGSVIGAITAVCIVVVAAIGFLVMRRRRVRSSGEQEASARPAAGSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDD5</accession>
    <name>A0AAD8YDD5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pyruvate carboxylase</fullName>
            <ecNumber evidence="4">6.4.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006552</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.4.1.1" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDD5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004736">
        <property type="term" value="F:pyruvate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06850">
        <property type="entry name" value="biotinyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07937">
        <property type="entry name" value="DRE_TIM_PC_TC_5S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000003">
        <property type="entry name" value="Acetyl-CoA carboxylase biotin carboxyl carrier protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000033">
        <property type="entry name" value="Pyruvate carboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.600.10">
        <property type="entry name" value="pyruvate carboxylase f1077a mutant domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003379">
        <property type="entry name" value="Carboxylase_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055268">
        <property type="entry name" value="PCB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43778">
        <property type="entry name" value="PYRUVATE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43778:SF2">
        <property type="entry name" value="PYRUVATE CARBOXYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02436">
        <property type="entry name" value="PYC_OADA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89000">
        <property type="entry name" value="post-HMGL domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0092">Biotin</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="2">
        <location>
            <begin position="487"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1742955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="562" mass="61125" checksum="6E68D5B60D919699" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDS9</accession>
    <name>A0AAD8YDS9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003957</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDS9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="359" mass="39770" checksum="8C36370ABDA74721" modified="2024-05-29" version="1">MEANCHFLHHQVKQRTTTTTNNNLQASYINNHRWHLSIPVAFLSIRGGSSDEREDKNTNNLEDDNFSVDFVSSFESELMEIRQEAELEAEAELEKLRLMLGEEEDDDEEESDLGSSEVEDDDTRADGNEEEDDNTIEPEEGNITDDEQNDGDEESSVVVVEEAVEEEEAKDVSDVEESAGEEEETKDVSDEEERISHTAINEEDQLGDKDEGIAGSEIAEEEIGDIKENVVEDEAVGEADDSSAKEDTVSATDDSDSKKQGKTKRSKAKKSKSSKPTSKSKKSSRQLLDDIGSLSEGELGTGDSVVLTRTVEIEVESRPRGISSFLKSDLVRALSLLIATIIVSVMMQRVQRQMEAQGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YE03</accession>
    <name>A0AAD8YE03_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tropinone reductase</fullName>
            <ecNumber evidence="4">1.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_004062</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YE03"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045000">
        <property type="entry name" value="TR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42898:SF6">
        <property type="entry name" value="NADP-DEPENDENT MANNITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42898">
        <property type="entry name" value="TROPINONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042050035" evidence="3">
        <location>
            <begin position="21"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1744771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="280" mass="30850" checksum="4B2D5834FC5800CB" modified="2024-05-29" version="1">MISLFVLLQGLAIVLSVAHASSTSDLSVPPPPAASFWRLNSRNALVTGGTKGIGAAIVTQLSSLGCSVLTCARNGDELSERLHEWNDQHGLNVQGIVADVSTPEGREMLRKEVEDRFGGKLDILVNNVGTNIRKKTPEYSEDDYNFVMKTNLESVFELTKLCYPYLKSSSTKPETSSVVNIGSVAGVTCMKSGTIYAMTKAAMNQLTGNLACEWGPDGIRVNCVTPWYINTPLAKQVLKDEAYKASVLEERLWDVWVNPMKWHLLLRSFVLLRRVISLDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YE67</accession>
    <name>A0AAD8YE67_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Carbamate kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_005075</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the carbamate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YE67"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008804">
        <property type="term" value="F:carbamate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019546">
        <property type="term" value="P:L-arginine deiminase pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04235">
        <property type="entry name" value="AAK_CK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1160.10:FF:000007">
        <property type="entry name" value="Carbamate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="entry name" value="Acetylglutamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003964">
        <property type="entry name" value="Carb_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30409">
        <property type="entry name" value="CARBAMATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30409:SF1">
        <property type="entry name" value="CARBAMATE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000723">
        <property type="entry name" value="Carbamate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01469">
        <property type="entry name" value="CARBMTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="Carbamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aspartate/glutamate/uridylate kinase" evidence="5">
        <location>
            <begin position="24"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1744542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="340" mass="36610" checksum="C628F4E4B27C1921" modified="2024-05-29" version="1">MNYVAWSMLSSSASKPKNNEKQHIVVALGGNALLKRGEPLTVDIQRQNIRYGISSLSAVLRSNTVTFVHGNGPQVGLLALEGAAYQKQTGAIPMQLDVLDAETEGSIGYMLEQEIDSALGDEGCKRGVITMLSQIIVSPNDEAFNNPTKFIGPVYSLEEANKLGKPVKQDGQFYRQVVPSPQPIQLIDQQLTALKLLTKNDVIVICGGGGGIPVIFDPVSRRLTGIEAVIDKDRAACMLGKTLGADGLMILTDVEGVAVNKDKPDEKWIKSASPAAILELADNFPAGSMGPKVSSAIDFVQTQRDRWCRIGSLKDATSMLEGKAGTKLTNEHGTDHLEYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEE8</accession>
    <name>A0AAD8YEE8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nibrin-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005532</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEE8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030870">
        <property type="term" value="C:Mre11 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007095">
        <property type="term" value="P:mitotic G2 DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040227">
        <property type="entry name" value="Nibrin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12162:SF0">
        <property type="entry name" value="NIBRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12162">
        <property type="entry name" value="NIBRIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="486" mass="52095" checksum="402E329C7B94799E" modified="2024-05-29" version="1">MFLRIDKVIGVPNSPPAPSNDSLHACLATAATVEPNVVAAPGEEEGGPAVIPDDTLNASGELFVVGRKNAAVTIDDKCVSRKHASIHLLSKTNPFSTTSSSPEILHGRLIMEYGTPSSPEEIAACDSSPSGVICVLRDLGSKFGTFVQVDEDLINATTPRTSNTDAVKEGSGNETGDETDDEGVNNTSINYATLSDGQVQAVRLLCDNNGSSSSSSLATPKFQKVEPNKSVTLLPLSHSTTPPPHHHTSLSSSEHITPKSTLQSYIDSLHYIGASHNQWDVNQSTHLVALEKKANAKAITAWASGRKSVVTLEYIDGLLGRKELGDVLPREEDYPPKGTSQLDSLSYSGDHSRALQGYCIAVMMEDDNGPLAQSAGAKILKVYDAPDSSQADFDNWWNTQQQNAIDAKMVLVLVDSKSSKCKPYNTWLHKRNDVRLTSAKHLAQAITGNNGEGDLLLDAKKVAIEKMEGWDAAIENVSAKKQSRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEG0</accession>
    <name>A0AAD8YEG0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutaredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEG0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042073935" description="Glutaredoxin domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="193" mass="21867" checksum="B2E15EA1FE648458" modified="2024-05-29" version="1">MISTQQFLCCCFVLLLHTSCAFQQLHQQPPSRRLHATRLHEMKRPILDRLATFVFKLENDRVDKASVIDDRGRNGEPMEWAEENSFANKFSTIVASNDIGYRFKQSVADLVAGDYDKHQQKNQSKTSSLQRRAIELDLLDGNKGNEIRAELGKITRRTSVPSIFIDGTYIGGAMMAIQGCSPSQEMQKDLIQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEW3</accession>
    <name>A0AAD8YEW3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CRAL-TRIO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_004208</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEW3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008526">
        <property type="term" value="F:phosphatidylinositol transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052578">
        <property type="entry name" value="PI_Transfer_CRAL-TRIO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45824">
        <property type="entry name" value="GH16843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45824:SF29">
        <property type="entry name" value="GH16843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="CRAL-TRIO" evidence="3">
        <location>
            <begin position="415"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1744917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="570" mass="64622" checksum="1B5B141C418547F1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEX1</accession>
    <name>A0AAD8YEX1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Sodium/hydrogen exchanger family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_004705</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEX1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015386">
        <property type="term" value="F:potassium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015385">
        <property type="term" value="F:sodium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051453">
        <property type="term" value="P:regulation of intracellular pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098719">
        <property type="term" value="P:sodium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018422">
        <property type="entry name" value="Cation/H_exchanger_CPA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110">
        <property type="entry name" value="SODIUM/HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110:SF86">
        <property type="entry name" value="SODIUM_HYDROGEN EXCHANGER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0915">Sodium</keyword>
    <keyword evidence="9" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="177"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="213"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="316"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="11">
        <location>
            <begin position="1"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="11">
        <location>
            <begin position="231"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1744172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="377" mass="41123" checksum="D303E01D2EC26D13" modified="2024-05-29" version="1">MPYTAIMFIVGAIMGFCSTENIGSNAVTESTKMWIHIDGEVLLLAFLPGLLFLDSYNTNVYLFKQAISQLLVFAFPMGLCGTILTALVAYFVLPYGWSTDLCMLLGSILAATDPVAVAVLLNELGAPPRLRTHIAGESLLNDGAAVVFFKIFSARFFHEMGVDGVGEEIGWSRGIVLFLRLSLGGAVVGVLFGVLLVMMLFNLNRHLRMLVEFDSFTLGGAVWASIIPDFTGSDWLYLLILYTAVIIIRFVLMALFFPLTSRIGVGQNMREMIFQSWGGLRGAVGIALALLLSKEVVEYSEAGNLSEETRHQYQQYVQKLFGMVGGVACLSLIIAGPSSGPLLRVLGLITPSETRSNVVSNHEKHLAKEYLSILSIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YF07</accession>
    <name>A0AAD8YF07_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005598</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YF07"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="230" mass="26577" checksum="6153502920DEDDB2" modified="2024-05-29" version="1">MAGPHKSKNENDDIPLPATPIPKQAEQNLKQTIMMSQVKEFFDSLPVEQKRNLSMGLRGGDGQKEETLVKISHLVQNQNFDGDIEQIGIEFYKLLNDFSSQVVVRNDEATTQIKNYFESLSDHQKRAMVVDLFGGDEQKKREVLGSLWRFDGDLLENTKFFVELVRDYTLTIEIGSLPQEDLQEKKDRGEKNEREHITAEKERVDDVVRRHKELYPLRQESALCVSTILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFW2</accession>
    <name>A0AAD8YFW2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">RPAP1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_004464</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140042">
        <property type="term" value="P:lipid droplet formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039913">
        <property type="entry name" value="RPAP1/Rba50"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009617">
        <property type="entry name" value="Seipin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21483">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21483:SF18">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06775">
        <property type="entry name" value="Seipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="64"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="265"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="444"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="271"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="296"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="450"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="470"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="509"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="524"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1745173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1472" mass="163330" checksum="1B62D3BD27867FEC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGF1</accession>
    <name>A0AAD8YGF1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Telomere length regulation protein TEL2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004375</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGF1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051083">
        <property type="term" value="P:'de novo' cotranslational protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051970">
        <property type="entry name" value="TEL2_Regulation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019337">
        <property type="entry name" value="Telomere_length_regulation_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15830">
        <property type="entry name" value="TELOMERE LENGTH REGULATION PROTEIN TEL2 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15830:SF10">
        <property type="entry name" value="TELOMERE LENGTH REGULATION PROTEIN TEL2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10193">
        <property type="entry name" value="Telomere_reg-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Telomere length regulation protein conserved" evidence="2">
        <location>
            <begin position="273"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="236"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="333" mass="37041" checksum="9EE8AB15FD05D7DE" modified="2024-05-29" version="1">MLSPLIANEELRDAIVNFIILSPPSSFQHYISPTGCPSLSSVDRAVPHCVTLLLHLACISCHESDSDAESESDDPNATSVDSYLSHLSTVASVWSEDVFVSRSGVLQQQFVTEFLLCPLRQNLISQGDFQRGMTSDGTSLASTLVQGVTLRLDISLSQPIRMDGMRIAEAMASLLGQHLRFDELHPAIEETMDGKEEETKVDQEKKPRKGRNRAIRRTRQVMIDPDAEYFTDESDSSSSHNGSSMNSSWGEEDSLEAYSLDDDEEDLRRVALPRTLQDCFAYLVAPDSDNLACDKQQAALMELARLVETKPFDLIDMTSTLVRVILHLEDKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGW2</accession>
    <name>A0AAD8YGW2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Flavodoxin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_003667</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGW2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030586">
        <property type="term" value="F:[methionine synthase] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050667">
        <property type="term" value="P:homocysteine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF84">
        <property type="entry name" value="METHIONINE SYNTHASE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="220"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="Flavodoxin-like" evidence="3">
        <location>
            <begin position="9"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1745743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="250" mass="27725" checksum="9EAC3A4AF296FEEB" modified="2024-05-29" version="1">MASSSAEEVLVLYGSQTGNSEAAAEQLSSLLPSKLSTSDNRTLTSRCMHLDDFLELEQAKWTRLVIIVCSSYGVGQAPIGARKFREVCDTILERFGYDDTTNDGKNNNGDKMLTGVNYALLGLGDSHYTTFFRNPTAFENALSSVGATRVGELGKADASGTGNMEQSKVIERWIDSIWKDLQPVIDKPMTEEEGLKLKKAHEQTWKLCLELYKEWKQTNYFALIGLFLPLGGVIVGILVHLYLHGYTWGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHJ9</accession>
    <name>A0AAD8YHJ9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003509</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHJ9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="526"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="633"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="672"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="811"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="76"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="554"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="573"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="633"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="683"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="817"/>
            <end position="844"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1072" mass="117897" checksum="6E7CC9FEDBD432E9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHK9</accession>
    <name>A0AAD8YHK9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHK9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006418">
        <property type="term" value="P:tRNA aminoacylation for protein translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1910">
        <property type="entry name" value="Cysteine-tRNA ligase, C-terminal anti-codon recognition domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="SAP" evidence="2">
        <location>
            <begin position="388"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="421" mass="47649" checksum="971EFCA2440C7C18" modified="2024-05-29" version="1">MKRASFFSARGKSPTPAADEHIKAIGYAIMSSTRRHKKAPPARLAISLTVVISLLFSSNALFVSAFLANHRRVTNNILHKRHYSPLYSSYRQNDSSSSHGYILEPNAGPIHPKCRLTENQIHVLISKRQRCKRQRQYDDADKILAALNQCGVFLHDKRNEWRADGKNHFGRRSDYVRRGSTYGLLSEEDISAVSTMVEDRSYAKKRGEFHISDKLGDILKTKYRVKVDDKNREWSVENIVEEDENGKVVIGGDYVPSPLCKLDGPTHTMDEDSKTLIAQRLAERSLCRKKRDYAMADKILDEMMAQYSVVVDDRTKEWKVVLGDNFEDDDFVKGALLSQRSAFVRGGKKTTEEHNITSAISERDEDSTTSTINEEEVIASANQNALDFDSMTVVELKEQLRQAGLPVSGKKADLILRLNQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHR2</accession>
    <name>A0AAD8YHR2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHR2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="146" mass="16135" checksum="821B555FC85BA97D" modified="2024-05-29" version="1">MYVGTAVTGTDKAVELEWVPAVSAYFGVGLAWLGPWMNFFVYAGEVAVAFMCTMYLPRVSPSFPAPIVAMLAVVVVEFGIARQFNIYTPLIMDYGGVQVKYPWTTVLSPEYSLPLSARWKLGRLSLVMARLFSPPNSSKLRLLSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHV1</accession>
    <name>A0AAD8YHV1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002188</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHV1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01763">
        <property type="entry name" value="Ubl_SUMO_like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022617">
        <property type="entry name" value="Rad60/SUMO-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10562">
        <property type="entry name" value="SMALL UBIQUITIN-RELATED MODIFIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11976">
        <property type="entry name" value="Rad60-SLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="206"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="281" mass="31112" checksum="C3E2D1B7803E4ACF" modified="2024-05-29" version="1">MGDVFDRYAARKEVNPDRLIFTRNGEIIDANQTVADLGLDANDLIDCVYDPETINIRFNSHDGPEITINIRRTDRISLAFDEYSSRSGIAEHNMLRFEFNGDEVHPDSTPENLWMNDNDMIHCSFGPLYNGNANGANEANGANGANEANEANEANEANEANEANEANEANEANEANEANEANEANEANEANDANDANGANEANESIVIFIKNQCGEVIRFRVRRSTRMMTIFRTYARRKGMRAQSFRFMTNGEVIDPALTLARLGLADGDMIDCVLNLCGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIT8</accession>
    <name>A0AAD8YIT8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phospholipase D</fullName>
            <ecNumber evidence="2">3.1.4.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001314</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.4" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIT8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004630">
        <property type="term" value="F:phospholipase D activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd09108">
        <property type="entry name" value="PLDc_PMFPLD_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21248">
        <property type="entry name" value="CARDIOLIPIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21248:SF22">
        <property type="entry name" value="PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="1">
        <location>
            <begin position="178"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="1">
        <location>
            <begin position="461"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="501" mass="55832" checksum="1416EDA42C7EBFB6" modified="2024-05-29" version="1">MNSFVNKLLCKGDVDESSGAELWDEDAVGLTHVGEAVHKVLARHHNNYHHKMWNVTRGKVVGSVHQTPMNVWGSSKDPKKNNDDWFPEKMAEIIGRTEKWCDIMSLGPPDGKFMTDFKAAIEKIAERSKTAEDTIIVRLLVGNIVGMPVNCTAVLKALTKDVPQDANMRVWVGAWRKGFSWNHAKLIAVDGVYLHTGGHNLWDQHYLKNNPVHDLSIELEGSVTRDGHRFANLQWEFIERNQRTCIGSCVDNMPDAMPTVLKTRVTVSEWPEGVADTFPPMFTKAVVAKTANYSRRNSTLEKDGVIDKGVPMITIGRLGTMVYRHRSADDAIIAMINSSQKIIRLVLQDIGPVTVPGTKRALPGLKWPKAYLAAIGEAIYQRGVDVEMVVSNPNSIPGGLKGTEANYGNGWSCVDVAAEIIKSIKKKHAEVDDGKLRAMVIDNLRICFLRHDKKGKYKDGKTIGLHSKHFIVDDVSTYIGSQNLYMCDLAEWESSLIVKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJ68</accession>
    <name>A0AAD8YJ68_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sulfotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001524</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJ68"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041929178" description="Sulfotransferase domain-containing protein" evidence="2">
        <location>
            <begin position="32"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="548" mass="61824" checksum="CE81EC8DD01727CD" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJQ0</accession>
    <name>A0AAD8YJQ0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_001809</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJQ0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021466">
        <property type="entry name" value="Put_rhamnosyl_transferase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11316">
        <property type="entry name" value="Rhamno_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="380" mass="42836" checksum="CE362748195CD563" modified="2024-05-29" version="1">MVHVIQTRFMQHQSHLTELGFARLALFEAFCLPSVMGQTSNNFLWIIRVDPNLNEEIVGRMKERIGSNENIILLGSNHNPEGMGRDNTDFDHFLGIERSNEHDSGIVFSGNVTLLREAFERSAASSSSVLLETRLDADDALHKMYVEFIQNQAQKYLMSNYVGEDTSDQSWRMWCIHSNVEWHPLNPYPMSTDEASTDDKSKEEGYLLMYSDKSICTTPGLTFGYGFGTTRSSILEGRRLKHSDIVSTIAHCDDDQKLKCVSRLKELSPGALRARTATSAGMVNIITGDDHLDQSSNGLKQKKGNEQLIKQFSQQDFLWEGVERLFSVTKASARDTRSLIVSRMKYIAADNLRGLCTPGHSCKENGKFLLSAILKQHEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJR8</accession>
    <name>A0AAD8YJR8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJR8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="259" mass="28951" checksum="5B64BA250CF149B2" modified="2024-05-29" version="1">MAHILRPTRHANDTHNMPPSSRYNSCSCIGTSGWDIIPRRFLAPPRLCEVDCLNAVLDTMSNWRVPSIMIPGNHDQIDYRGSEHALTPLSNAYRIKSSVPHNTELEKQYYAGPLILSHPTKFLDAFFIPHIRDKAMMKSILSSEAVAQSSALFVHADVKGASMNDLIKSRNVKDPRFGMWKSVSNLKFRGGSIQIITSCGFTKMWECIEEIPLDIGPRFHRLSSVNEFLGMSEEEINGVGVNKKLRSGDKVIVAVSQAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJX1</accession>
    <name>A0AAD8YJX1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sel1-like repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_002069</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJX1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="13"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="78"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1746725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="301" mass="33546" checksum="5F15AE29B23011B5" modified="2024-05-29" version="1">MSEENIKADTSCCAYCGVAEVDEIKLTECSDCDLVRYCSVKCQKEHKSQHQQECKKQVDELHDELLFKQPESSHIGDCPICMIPLSIDQTKSGVWSCCSKVICKGCAHANILREEDKKLQHACPFCREPVPSTQEQCDKQMMKRVAANDPVAMRRKGIQQHKKGDYRSAFEYYTRAAELGDAAAQCNLASLYEFGKGVEKDGGKAVHYLEEAAIGGDPIARNRLGRIEGNIGNTERAVKHCIIAANLGDDGSIKMMMLMFRNGLVSKDDLASTLRAHQAAVDATKSPQREVAEEYDRLFHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YK06</accession>
    <name>A0AAD8YK06_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glutathione transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_001766</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YK06"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="122" mass="14042" checksum="62D582FAC610905C" modified="2024-05-29" version="1">MGSSPAFTDEDNGIAIWESGAVLTYLLETYDTQHKFHPKQGTATPLERANFLHLQQYIIATVYPFLASLFLQTLKPEHEQDQGYISSAKEKCYIVSTYSHWLFGRTALLHGKCHFVYRFFDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YK27</accession>
    <name>A0AAD8YK27_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Vacuolar protein sorting-associated protein 13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_001416</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045053">
        <property type="term" value="P:protein retention in Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026847">
        <property type="entry name" value="VPS13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026854">
        <property type="entry name" value="VPS13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009543">
        <property type="entry name" value="VPS13_VAB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16166:SF93">
        <property type="entry name" value="INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16166">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12624">
        <property type="entry name" value="VPS13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25036">
        <property type="entry name" value="VPS13_VAB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Chorein N-terminal" evidence="5">
        <location>
            <begin position="138"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 13 VPS13 adaptor binding" evidence="6">
        <location>
            <begin position="3717"/>
            <end position="3878"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 13 VPS13 adaptor binding" evidence="6">
        <location>
            <begin position="4195"/>
            <end position="4373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="49"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="110"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="204"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="259"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1956"/>
            <end position="1981"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="3366"/>
            <end position="3387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="125"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="207"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="229"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1956"/>
            <end position="1968"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1969"/>
            <end position="1981"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="3366"/>
            <end position="3381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1747453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="5183" mass="573918" checksum="0F95D53D50A36312" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YL49</accession>
    <name>A0AAD8YL49_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000312</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YL49"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="37"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="307" mass="35795" checksum="F7703F57F1BB53AC" modified="2024-05-29" version="1">MELVVITLNSYRIGRVLFQRYMADQLGEEWKNFREQHLSVLDNVDFYKLISIATEETYEEGDVVMIQGTANPKVRIVIEGELEVLRDGTLTYVLEKGNFVSESGLHAGLLLSGSMEACGSIVVGPPFDYPSGEKKQQQNNHHDNNVQKKSSRRNKVRVLTWDRTELVQLLEADKGLRNSLKAALSWDIVRKLKTQRHMLVEGRVKDPTSWTKKREDQGISRYAAILQNMLRLPPEEVQAMSQELNKYRLIHHIDDADHERALAKCGWTKEEFRLGRQEKQDEFEEDDDMDEFESVRWRKVRRFSSKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLG5</accession>
    <name>A0AAD8YLG5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pentatricopeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_001483</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLG5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057027">
        <property type="entry name" value="TPR_mt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23276">
        <property type="entry name" value="TPR_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="111"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="146"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="182"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Pentatricopeptide repeat-containing protein-mitochondrial" evidence="4">
        <location>
            <begin position="189"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="217"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="252"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="308"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="323"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1747520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="339" mass="38009" checksum="4ECAED6229348E57" modified="2024-05-29" version="1">MLQNVDGGGDTIPASTYHAVIEACCAGKVERHNNKKYNKNNSSSNNNKSAMDKINEAADLLTPWERRLHHMHMRHLFQDMRVGAVARCLPNTCGVGRKFGSSDDKDNAVPSLNVYQTVLIAFVEAGEYDHMNSLLTRMRRRGVRPTVFTYNSLLKICAQTARWREAVSILSQCQREPGVNPDLVTFTSTIRACARARKTDKAMEIFRVVKDMGVKMDVYCYTTAMDACAKGRRWKVALSLLDEMKEKGIEPNEVSYGVAVSACGNGGQWEKALELLEQMRKENMKINTITYNSAIAALAKAARSESRQQRRYDYKPGGGWSKVESSNPAYNDTTFGRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMA8</accession>
    <name>A0AAD8YMA8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Prolyl endopeptidase</fullName>
            <ecNumber evidence="6">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_001855</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Serine peptidase whose precise substrate specificity remains unclear. Does not cleave peptides after a arginine or lysine residue. Regulates trans-Golgi network morphology and sorting by regulating the membrane binding of the AP-1 complex. May play a role in the regulation of synaptic vesicle exocytosis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S9A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMA8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.120">
        <property type="entry name" value="Prolyl oligopeptidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023302">
        <property type="entry name" value="Pept_S9A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002470">
        <property type="entry name" value="Peptidase_S9A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051543">
        <property type="entry name" value="Serine_Peptidase_S9A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11757:SF19">
        <property type="entry name" value="PROLYL ENDOPEPTIDASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11757">
        <property type="entry name" value="PROTEASE FAMILY S9A OLIGOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02897">
        <property type="entry name" value="Peptidase_S9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00862">
        <property type="entry name" value="PROLIGOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50993">
        <property type="entry name" value="Peptidase/esterase 'gauge' domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9A N-terminal" evidence="10">
        <location>
            <begin position="124"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="9">
        <location>
            <begin position="660"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="96"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00045448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1747892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="890" mass="100452" checksum="63ACD71C314734F7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMQ6</accession>
    <name>A0AAD8YMQ6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DHHC family palmitoyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.225</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000786</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMQ6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="202" mass="22417" checksum="5BA22D9B5D99EDC3" modified="2024-05-29" version="1">MRASTAQQQYDNMFLNSGEQTKPGCDAMMNSDSMIIFTLLVIVTILFFFFTCCMLIEQGEAVDTNMSKIARMKTRAGLSNADEYRPVATEFNEVFGGEHPTLSWHWFLPLPVRFPEWARDNVLGYEYNSTFPPVPYQEPSDTDAESVASRGSSVSLGRMSVTSDRDLGDVESDIENVYVGGGVTLDQDSSSVKKRSTTASIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMS7</accession>
    <name>A0AAD8YMS7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000056</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMS7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="426"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="515"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="604" mass="66043" checksum="FF938C1A7BD806A0" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMT8</accession>
    <name>A0AAD8YMT8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Protein-serine/threonine phosphatase, PP2C family</fullName>
            <ecNumber evidence="8">3.1.3.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_000071</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMT8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47992">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="7">
        <location>
            <begin position="107"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="489"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1748132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="512" mass="56462" checksum="61C69DA0F003888F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YP48</accession>
    <name>A0AAD8YP48_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pirin family protein</fullName>
            <ecNumber evidence="6">1.13.11.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_000989</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the pirin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.24" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YP48"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008127">
        <property type="term" value="F:quercetin 2,3-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02910">
        <property type="entry name" value="cupin_Yhhw_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041602">
        <property type="entry name" value="Quercetinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43212">
        <property type="entry name" value="QUERCETIN 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43212:SF3">
        <property type="entry name" value="QUERCETIN 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17954">
        <property type="entry name" value="Pirin_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042143416" evidence="3">
        <location>
            <begin position="23"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin N-terminal" evidence="4">
        <location>
            <begin position="72"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Quercetin 2,3-dioxygenase C-terminal cupin" evidence="5">
        <location>
            <begin position="211"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1749050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="317" mass="34911" checksum="49E7FB70699F5B7B" modified="2024-05-29" version="1">MINTASVLKAIASFSFFAKVTGISSSSSEPMCAHKASHRIVKVPSSKLFVSEPNPSWFGNEGNPGYNPSWTETNWLKSRFHFSFAEYNNRRNSNFGCIRVVNDDLVQPSRGFGTHPHANQEIVTYIVEGELTHQDSMGTKESLGRGSVQFMTAGTGVRHSEHNLSEDKPLRFIQTWITPSRNNLPPNYGSSVGDEVMRWNQWQHLVSSVDNRGTEATVQINQDCNAYSSELEMGKTINFPVSEGRMAYMIALEGSVKVGDVVLERHDAAEITPLSSEGNGVLDVTSVAVEKAEHGKDVAHVILFEMQHVPGAGRGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D389</accession>
    <name>A0AAD9D389_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_017061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000078">
        <property type="protein sequence ID" value="KAK1732236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D389"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1732236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="146" mass="16354" checksum="6CE2FC2ED0B5C51F" modified="2024-05-29" version="1">MDVQDCKYYEARAKDVNLEDITSSEQNAAILARLRDNDPTFTAISIEDGPQVESNFVAREGDCMGWLGYFVGRSKQCAHNIALMLGQQSTLKYLNFEETNLMDEMLVEIAAALSSQPQLEELDLGSNNIARNGCVALGLRWRFEEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4H4</accession>
    <name>A0AAD9D4H4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">coproporphyrinogen oxidase</fullName>
            <ecNumber evidence="4">1.3.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_016666</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aerobic coproporphyrinogen-III oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.3" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000061">
        <property type="protein sequence ID" value="KAK1732689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4H4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1500.10:FF:000002">
        <property type="entry name" value="oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1500.10">
        <property type="entry name" value="Coproporphyrinogen III oxidase, aerobic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001260">
        <property type="entry name" value="Coprogen_oxidase_aer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036406">
        <property type="entry name" value="Coprogen_oxidase_aer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018375">
        <property type="entry name" value="Coprogen_oxidase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003727">
        <property type="entry name" value="PRK05330.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755">
        <property type="entry name" value="COPROPORPHYRINOGEN III OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755:SF0">
        <property type="entry name" value="OXYGEN-DEPENDENT COPROPORPHYRINOGEN-III OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01218">
        <property type="entry name" value="Coprogen_oxidas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00073">
        <property type="entry name" value="COPRGNOXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102886">
        <property type="entry name" value="Coproporphyrinogen III oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01021">
        <property type="entry name" value="COPROGEN_OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041980369" description="coproporphyrinogen oxidase" evidence="9">
        <location>
            <begin position="17"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="57"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1732689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="404" mass="45246" checksum="822977BA230845E9" modified="2024-05-29" version="1">MKLSSTLLFAISAVTAKGFAPIATVPTSRTSSLKGTASPTVEKESFQRSLLAAQLANKKTNGKKAEDAPPVNIGWDSHKPVDKAPDSLVRPGDGPDGNYPMRARFEQMIREAQISITDAIEKIDGKAKFQEDSWIRANGGGGMSRVLKDGAVFEKAGVNLSVVYGSMPQEALQAATERGVDRAKGMAPGERVPFFACGLSCVMHPRNPHCPTMHFNYRYFETDGGVWWFGGGTDITPAYLNEDDMRHFHGTYKEVCDRHDPEFYPKFKAWADKYFVISHRNETRGLGGIFFDDLNDREPEKLFEFAKDAVNSVVPAYGPIIEAHKDDPFTEQQKQWQLMRRGRYVEFNLVYDRGTVFGLKTGGRIESILMSLPETARWEYDHHPEPGSPEADIMDAFKHAREWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4Q1</accession>
    <name>A0AAD9D4Q1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016452</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4Q1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="146"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="209"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="170"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1732914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="597" mass="67202" checksum="95930D7831EC7A90" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4S7</accession>
    <name>A0AAD9D4S7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heat shock factor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_015294</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1734036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4S7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000479">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF206">
        <property type="entry name" value="HSF-TYPE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="5">
        <location>
            <begin position="80"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1734036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="162" mass="18550" checksum="976A4ADB14290A38" modified="2024-05-29" version="1" fragment="single">MKMNPPSDNDWKIASSIASSFVVGDKGGFPDAKFVFHSAPSDDDEEASSDNLPRRFADHTYRDFSTYIKDGGKVQKHKKSESNFPARLYAMLAEEKYSHIISWMPHGRAFKVHNKKLLLEEALPKYTGQSKISSFTRQLSGWGFKRLHQMGLDFGCYYHECF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4W2</accession>
    <name>A0AAD9D4W2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015414</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4W2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="61" mass="6526" checksum="2FE80F2C5E2FA6EC" modified="2024-05-29" version="1">MIAATEKQALEEAAAAEERRQDSGDPQGHHQTDDTVLRKAAMMTDAGMDLTVIASSTRALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D596</accession>
    <name>A0AAD9D596_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AP2/ERF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_015954</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000050">
        <property type="protein sequence ID" value="KAK1733395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D596"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51032">
        <property type="entry name" value="AP2_ERF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="122"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="71"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
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    <sequence length="227" mass="25611" checksum="765428863C1C6D02" modified="2024-05-29" version="1">MVTKIVIHIAPAERAAAAAEVSNRDVNRLQNNRRNDLFDQSSREEGNHYSFQGSLNKVSYGGICAGHSCHDNASPRVNNNSKKRPLLVKGAGDAEEKKRRKRTQKLIDLTDVPAQPPILKSSRKGTSKYHGVSKASKKWKAQIAIDGKTHYIGNYDNEEQAGIDYARAVFKYNSTRKRTPFSPLGPLPLPDPKEMEERHRKALAFVMMSDQDREKVKRQWRETSQAA</sequence>
</entry>
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            <fullName evidence="7">Calmodulin</fullName>
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            <taxon>Coscinodiscophyceae</taxon>
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            <taxon>Skeletonema</taxon>
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        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
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                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="5">R05AC</strain>
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        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
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        </submittedName>
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    </gene>
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        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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</entry>
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                <person name="Bruchert V."/>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6M0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1735837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="69" mass="7193" checksum="E6AEEF9EB8278274" modified="2024-05-29" version="1">MDENGLSTTDATVHKNSLVKDATATELASSSAEKGYSPSLNDDCSVTVSSDCTAHVPFERLSLAPASFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D781</accession>
    <name>A0AAD9D781_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_012758</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D781"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="131"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="287"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="194"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="131"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="142"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="297"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="308"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1736736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="347" mass="38555" checksum="815C6A1D43F7D5B4" modified="2024-05-29" version="1">MSSSKEEASSAPPAAASAAAKPDASEADFLLFGSRPSHLFDDMRITLDTLLTEEVASLPLLPRTLTPSQRQQQQSGNGEKPLTGEQKLIAELRKAYKKKLDLAEAYCSRNIFTIQFYNKTKRRKIMERVLGEDDNDDRSSNNEDDGQDNDDNDKKKKAFSPLPAITFERPSGEIPSADEMNGKNKEILQARQQIQHDKQRRVQLSRQLDRLTKAAQQLKELRGALDKALESKKTSGGTEGESSNTALAMKELQESVAKAVEGHEELKVWNARAEEVIQLMDQIKDEREEGGGLLGGSQNANGSSKRVTSREEDERERKRMLTEMGGGETATHGTKEEIASLLNKIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7V9</accession>
    <name>A0AAD9D7V9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">REJ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013109</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1735973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7V9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041918608" description="REJ domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="139"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="160" mass="15656" checksum="360D929793DD3859" modified="2024-05-29" version="1">MKLFYFLLIGLIASSAATTSKASKSSSGTSPSKSSKSNPSPTTSKSSKSGSSPSSSKGSKSGSSPSSSSSSSSGKSGKSKPCSTSSGSSSSSKSGKSKPCSSSSSSSASSSGKSGKSETSPSSSSKSGKSEPERRELSGSKSSKSETSTKSSKSSYDDPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D833</accession>
    <name>A0AAD9D833_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ADP/ATP transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_012905</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D833"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="32"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="154"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="264"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1736305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="354" mass="38516" checksum="D1314EE7CD04BC0F" modified="2024-05-29" version="1">MKQPEPSTDRGSSSLQRQEETTVSSQTTHGAADMTRRMVCGGLAGMIAKTATNPLDRIRMLSQTGEHGIKLSSSTTTTTKQITPLQLYKSILQNEGILGLWAGNGANLLRVFPAKSIVFSSNDFYRGVAHTLYFGNDVDNNNNNYTTQQQKQQLPWMLSFLSGGLAGMTASAATYPLDLARGRITGKLAGPGGKKHYKGIVNTVLITAREEGVRALYKGVTPTLLGAMPYEGIKFGTVGMLERAFPKSSTGEEQGGVLSNNIVRKLVFGGAGGVSAGLLTYPNDTIRRLLQLQGSKGTTEHFDGYFDCLRKTYAKYGIERFYRGAFINIVRMAPNTAIQFGSYELLKQMSEGYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D861</accession>
    <name>A0AAD9D861_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine/threonine-protein kinase</fullName>
            <ecNumber evidence="5">2.7.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_011603</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D861"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="399"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="111"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="249"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="707"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="111"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="259"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1737831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="739" mass="82834" checksum="D6DE09A7E671930E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8G0</accession>
    <name>A0AAD9D8G0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">fructose-bisphosphate aldolase</fullName>
            <ecNumber evidence="5">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_012702</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class II fructose-bisphosphate aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8G0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006411">
        <property type="entry name" value="Fruct_bisP_bact"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006628">
        <property type="entry name" value="PRK09197.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30559:SF0">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30559">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00806">
        <property type="entry name" value="ALDOLASE_CLASS_II_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1736680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="220" mass="24419" checksum="9E1E3CEA60E01C36" modified="2024-05-29" version="1">MLDLSEEPLEENIGICKDYLEKFAKVGILLEFELGVTGGEEDGVDNTDIDSSRLYTQPEEVFYAYEQLSQVENGAFTCAASFGNVHGVYAPGNVDLQPKILMNSQAYIKEKIGSDSDKPMKFVFHGGSGSDVSDIQEAIGYGVIKMNIDTDTQWAFWDGVRAYEAKYHDYLQGQIGNPEGDDKPNKKYYDPRMSLRAGEEAMAARLIKAAEDLKCVNVLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8V0</accession>
    <name>A0AAD9D8V0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TRPL translocation defect protein 14-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011936</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8V0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070300">
        <property type="term" value="F:phosphatidic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01983">
        <property type="entry name" value="SIMIBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.320.10">
        <property type="entry name" value="Hypothetical Protein Pfu-838710-001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038727">
        <property type="entry name" value="NadR/Ttd14_AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053227">
        <property type="entry name" value="TRPL-trafficking_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34932">
        <property type="entry name" value="TRPL TRANSLOCATION DEFECT PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34932:SF1">
        <property type="entry name" value="TRPL TRANSLOCATION DEFECT PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13521">
        <property type="entry name" value="AAA_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NadR/Ttd14 AAA" evidence="2">
        <location>
            <begin position="62"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="447" mass="50642" checksum="97AD7B121A8838E1" modified="2024-05-29" version="1">MSAPPLPYERKPSNTTPSAFSARNLSQTRLRSNSHGPLAQDISAELTQAEVNSIAPPAPIYKIVLTGGPCGGKTTSMARLSPYLRERGFEVITCPEAFSLLVNNGMAFDYLSAVKGMDIVVQDTVMDMQIGMEDGFERVLRARGKPAVLLCDRGLMDGSAYMKEEDWNKLMQKREIGCVSELREGRYNAVFHLVTAAEGAEEYYTLENNAVRTESPELARSLDSMTLNAWVGHPSLKIFDNSTDFETKMQRVVEETARLVGLPTHLQKVTTKFLLKKEPDLSSFPREVAFQIFEVEKVYLYEENEDVSQENVLKEYSFIRKRTSLRKSGKESGSVYGWTSVQKMKDGQRIEKKRIITKREYLSLFNNRDKTRHIVRQKRISFLWNIQSFNVHVFKEPSDVCILHAQVRSSPGSGDTVDMPSFLDVDRLITDSVEDEIYGAYQISLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8Y7</accession>
    <name>A0AAD9D8Y7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">WD40 repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_012056</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8Y7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10971">
        <property type="entry name" value="MRNA EXPORT FACTOR AND BUB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="127"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1737189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="363" mass="39624" checksum="ED07516338C7ECC8" modified="2024-05-29" version="1">MSFGAAVAPAPQLVGSCTSGTTDRLAPQDHCVQSAGGDGISSLRWSSTANHLVSTNWDGGVRCWEVQEQGGQIRALPKAQVNHEGNAPVLDCCMSPDGNTVFSVGADKAVRMWQLGQAPPNNVPQQIGSHDQPIKSVGFLKSSNMIVSGGYDKMLKFWDARQPNPVAQIQLPERVYDLDVSDSLMVVACAGRHILTYNVQGQPQEHERKESPLKFQSRCVAAFPDNTGYAVGSIEGRVGIQYVTKVPGKESFAFKCHREGNNVYAVNHIAFHKGYGTFSTVGADGIVNFWDKDNKQRLKGFPAIHRTITCAQFNAQGNMFAYASSYDWSKGSSQHAPNTPNEIFVHHVQDEEIKPKGKKSGYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9K1</accession>
    <name>A0AAD9D9K1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transmembrane amino acid transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_010423</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9K1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF458">
        <property type="entry name" value="SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="536"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="562"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="610"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="670"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="709"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="740"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="764"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="803"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="826"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1018"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="9">
        <location>
            <begin position="533"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="9">
        <location>
            <begin position="660"/>
            <end position="857"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1739107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1043" mass="115269" checksum="35CA709E65263274" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9R5</accession>
    <name>A0AAD9D9R5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009964</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9R5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1739421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="103" mass="11489" checksum="456AA98D2F298531" modified="2024-05-29" version="1">MQVYAGLIGIPFNSLYKYLNPNKDERRILGNGERGRPKLLGVDDVQFLGETLARMDRCNDGASKKEGTDLVMSAVPNLTRPQASRQLSRIVIPEGHKAGIQWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9S0</accession>
    <name>A0AAD9D9S0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sulfotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011428</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9S0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053259">
        <property type="entry name" value="Golvesin-related_Golgi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32301">
        <property type="entry name" value="COUNTIN RECEPTOR CNR3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32301:SF6">
        <property type="entry name" value="GOLVESIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="197"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="578" mass="64747" checksum="62F8247381D86CDB" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAK8</accession>
    <name>A0AAD9DAK8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010335</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAK8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="462"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="494" mass="55114" checksum="45A47ED331D27128" modified="2024-05-29" version="1">MSSLSQRSNASSTTLPFILDETTRIGNGCKPNPNKMPGHKSSFTVTVKVFRIGAMLVLLVFPLIRNFQSLLLLHQLQDDDNKEGLMNLPMLESSSRLGGKNDIANKVATIIHQSSSEETTQEYQKQDGLHIAKTAAVHIHHNITDKNVSTEDTIEEQKTDGPSCKCVFCDEDEVCGGLWVGNRYPGMISDEEAMNRKLHIVVSHCKTSVSWIPRYIEKFTNVASIHVISKCGHTVEGVPENTTTLVIRNVGRNDHAFAYYITSILPKLASPNDNSTVIFLKDTVEDPIHQGNHFIRSDFKSLVRVSSSENGFACGLHSDGPISAYHDASSLFQFTMGSYNRTGMYKKYADDIPFESPSYNNLGEFYNSLNATSSSPQIVQACYGGIFAASTANVFKQDMKVWKALEKSLERGDNIQEGHYTERLWGILLATPLKSFQVEALREHSSGVRGYPHNGQLSNGLWRRKNKKRRVGRYGRRKGNTRVSTSGNTRKPIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAM2</accession>
    <name>A0AAD9DAM2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010778</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAM2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="695" mass="76887" checksum="DA929874F80EB2FE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDE5</accession>
    <name>A0AAD9DDE5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WD40 repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_007263</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat EIPR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDE5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059104">
        <property type="entry name" value="Beta-prop_EIPR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040323">
        <property type="entry name" value="EIPR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14205:SF15">
        <property type="entry name" value="EARP AND GARP COMPLEX-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14205">
        <property type="entry name" value="WD-REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23609">
        <property type="entry name" value="Beta-prop_EIPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="EIPR1-like beta-propeller" evidence="5">
        <location>
            <begin position="342"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="23"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="170"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="526"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="183"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1741690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="617" mass="67473" checksum="5EA1217AF8F3C497" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDF6</accession>
    <name>A0AAD9DDF6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007547</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDF6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042235015" evidence="2">
        <location>
            <begin position="19"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="242" mass="27096" checksum="84948210276FA415" modified="2024-05-29" version="1">MNTMQQLVYTLTLLPALAEAIYRCNLRIVPPTCHQHTQALGLNSVRPERRLLFTFDAGEALAKLGVTGKVFGTEVKGFGLLAPDFLYNDSCTKVAKHSMLIGTILSVIVYYTMISKRRQSIRTIKKMTIAGSIIALLLLTPYIYFDVMDIKQSAVRQPFAMSVIMITFRVIEAAFGFAPEGVTTSLGIYMIYFAFSGCEFIFDAKTSKPVKASAYDIFQSLWRLLRVGIINTLFFSYVFSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDI9</accession>
    <name>A0AAD9DDI9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005278</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDI9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="159"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="233"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="317" mass="35146" checksum="BCCE2172E725B8AC" modified="2024-05-29" version="1">MRRQSQASAGISSGGSTPVISNHNNLTGDRRVSNLSQGGNLDAINEQKPVDIGVVNIPSSQLQRQQQQQQQQMDPGSGCDRCVQMESAILSLQADIEYVRTLELQKEFVCRECESGPAPPAQSVSSAVSLGSRVKQSHYERAYWQNDMHLKLEKFAMMCKNLNEDAAQRSNEVKELTSKLEKVTSERNGLVSQVETLKARVGLYEGESVVQSRLRDNFEKGEAGALDLFDKAMKGRDETIEDLSNRLAAALEELSEKAKLSLEASMVQSSEREKALQSQLDVLEQELEQARAILQDTDDHYLEAQLSMKHTSSNSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DF82</accession>
    <name>A0AAD9DF82_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">homogentisate 1,2-dioxygenase</fullName>
            <ecNumber evidence="4">1.13.11.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_006094</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 4/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the homogentisate dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.5" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DF82"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004411">
        <property type="term" value="F:homogentisate 1,2-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006572">
        <property type="term" value="P:L-tyrosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07000">
        <property type="entry name" value="cupin_HGO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000034">
        <property type="entry name" value="Homogentisate 1,2-dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046451">
        <property type="entry name" value="HgmA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046452">
        <property type="entry name" value="HgmA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005708">
        <property type="entry name" value="Homogentis_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01015">
        <property type="entry name" value="hmgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11056">
        <property type="entry name" value="HOMOGENTISATE 1,2-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11056:SF0">
        <property type="entry name" value="HOMOGENTISATE 1,2-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04209">
        <property type="entry name" value="HgmA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20510">
        <property type="entry name" value="HgmA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="9 12" id="KW-0408">Iron</keyword>
    <keyword evidence="5 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="domain" description="Homogentisate 1,2-dioxygenase N-terminal" evidence="14">
        <location>
            <begin position="15"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Homogentisate 1,2-dioxygenase C-terminal" evidence="13">
        <location>
            <begin position="320"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="331"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="375"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="381"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="390"/>
        </location>
        <ligand>
            <name>homogentisate</name>
            <dbReference type="ChEBI" id="CHEBI:16169"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="416"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="416"/>
        </location>
        <ligand>
            <name>homogentisate</name>
            <dbReference type="ChEBI" id="CHEBI:16169"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR605708-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR605708-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF20510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1743473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="483" mass="53037" checksum="4AB6FCE1A49FD826" modified="2024-05-29" version="1">MCVGSKSSCSKEELTYHHGFGNHFESEAYPGALPQGRNNPRIVPLGLYTEQLSGTAFTAPRNENRRTWLYRAQPSVSGTSNSFYACGGSDGTVSSSLPEIFGGADWSTDMKLDPNPMRWGATPLLRSGERVNFIQGVHTLLGSGDATCKSGIGIYVYAFNTNMSGSASGGEDLHMYNSDGDFLIVPQQEALWIQTEIGRLTVAPGEICVIPRGIVFTVNILNPENTAEDGSFARGYMMEIFRGHFMLPELGPIGSNGLANSRDFLHPTAHYESEDSQANKSCIIVNKFGQHLFQRSNPHSPYNVVAWHGNYLPYKYDLGRFCAVNSVTYDHPDPSIYTVLTAKGDENGTALADFVIFPPRVMATDQNTFRPPWFHRNVMTEFMGLIYGKYDAKKGKNGSGGFVPGGASLHSIMTPHGPDAASYDANVKNPCDEPTKFEGGLAFMFESSAMCKLSQYALNCEQRERDYASCWDGLDRAFPTRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFA2</accession>
    <name>A0AAD9DFA2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CAP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_003450</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFA2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041967509" evidence="2">
        <location>
            <begin position="21"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="3">
        <location>
            <begin position="230"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1745526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="395" mass="43902" checksum="3EA7B463C8F76D02" modified="2024-05-29" version="1">MMLFARQLLLVLLPQVFCSAAATDAEDASPPIRKRTQHRHSSSNSSTHLRGGSTTRDTDNFDPFIGVPRELRADDLTETTSRSMSLSMSTTSAPTTSTPTTTPTIVQFDYEPCDDPNLVPIEVNIITDRFAKEDETGYRLISHPEDSTEPVTYLERTEMDNSATYTDKICLPKGRYIFTVYDKLNGLCCGGGRGDYSVKSKGIEILNGGGFPAPEISYTILAGVEADMSDEDRQWLDGHNSRRRTFHIDNGKTFKPLVWSESLAKAAADFAATITFNCQILQKTDPWGQNVAIYSNSVISQNQILPDTVLRYMFDRKLNADYPNNNQLTQIAWRGSRYVGCASLIEQSNSGAYCHVSVCKYARPGNCSVNMDNWLEKTLADRSNCGRACPDDICQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFI2</accession>
    <name>A0AAD9DFI2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004817</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFI2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="264" mass="29901" checksum="95F5754CB2C650BE" modified="2024-05-29" version="1">MAASGKNANQYESWYGNMLSTVGKTELKELIVEAEKAGLSLAVHAAKKLGLDSKEYEGIETPFVMVSWSTIKAGKGEPELNDKLKTEYKNRKLPVADRESKFSEERRSKMSKANRDNYSGVGKSESTLKLYHDVQKEVVGSDTSRLWNWCKDGVPPEHEHLDFECKFLRDADESGAWNGAWIKNLQGFAVACHGKEYYENSNSAAIKVLGNLRTCGWREAKSNELMNIGKRCDNPELELFLFHKNFFPEGKGKKMMNTITPPWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGL0</accession>
    <name>A0AAD9DGL0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PPP1R11/YPI1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004386</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGL0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008157">
        <property type="term" value="F:protein phosphatase 1 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004865">
        <property type="term" value="F:protein serine/threonine phosphatase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011107">
        <property type="entry name" value="PPI_Ypi1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20835:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PPP1R11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20835">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PPP1R11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07491">
        <property type="entry name" value="PPI_Ypi1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="173" mass="18447" checksum="FBD361973354F418" modified="2024-05-29" version="1">MESSSNHQTAASRHIQDANATTDLNNDDERRSGQYTSGNVNDSSGGASSGAAGTATSTMVITQQQQSQANNIEEPILRLSLRPQSNVTWDQNVVNNEGLGRKSSKRCCIWHKERVFGESSTESSEEDGDDDDNSTSSSSSGGAGGGRAQRPIAKKKMGGVGKPKVPDYQRFHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHL7</accession>
    <name>A0AAD9DHL7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002767</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHL7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="245" mass="27116" checksum="AA6CDAC8AC50BD28" modified="2024-05-29" version="1">MSDANFLASMTFASGEACNCDECDCGPSVPLDIQRAVQEHLRKRKLEEPVFESSQQLNIQQQRELVKRESGVSVWKLVLPRYHGRGADPIVEFRNSHRVLFVKKMPQNATIQSIGKGIIGSAAEESGRTIVNWKQCSSYFLPCLSGVACGWVNTTQITEEKSSSGDSDDANNPSGGDSVVLYTMKVSPRDLERNQKEDETQQLSPWVAKAVELFDSMSSVETSDEIMLSSEESAKVSEIFDLVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIU5</accession>
    <name>A0AAD9DIU5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001712</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIU5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="609" mass="66527" checksum="35B1238E4C3F00BB" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DKX7</accession>
    <name>A0AAD9DKX7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sorting nexin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001112</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DKX7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555:SF170">
        <property type="entry name" value="FI18122P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="2">
        <location>
            <begin position="315"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="233"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1749173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="690" mass="73311" checksum="8696B0D1F0003B52" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2020-12-02" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6U3TWB8</accession>
    <name>A0A6U3TWB8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Chlorophyll a-b binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_010463</name>
        <name evidence="10" type="ORF">SMAR0320_LOCUS5897</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated. Energy is transferred from the carotenoid and chlorophyll C (or B) to chlorophyll A and the photosynthetic reaction centers where it is used to synthesize ATP and reducing power.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fucoxanthin chlorophyll protein family.</text>
    </comment>
    <dbReference type="EMBL" id="HBGZ01008281">
        <property type="protein sequence ID" value="CAD9587989.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6U3TWB8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030076">
        <property type="term" value="C:light-harvesting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="8" id="KW-0157">Chromophore</keyword>
    <keyword evidence="7" id="KW-0437">Light-harvesting polypeptide</keyword>
    <keyword evidence="5" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042404959" evidence="9">
        <location>
            <begin position="16"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CAD9587989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1739147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="201" mass="21621" checksum="F35B4A6A62E4B9BA" modified="2020-12-02" version="1">MKTAILTTLVAGAAAFAPAQTGKASTALNAAFDSEIGAASAELGCWDPLGFVTNGDQSRFDRLRSVELKHGRVAMLATWGYATTWSGARFPGCEDQVAGHQAVFSGPEFLVPVLLTAGFLEITWKQKEGSFPGDFSATSFPVGFGPYARNEQDMIDLRTRELNNGRAAQMGILGMMVHEQLDGKPFIFFDKFDIYAPSVGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2LE40</accession>
    <name>A0A7S2LE40_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transporter permease, ArsB/NhaD family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_014700</name>
        <name evidence="9" type="ORF">SMAR0320_LOCUS11201</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="HBGZ01015672">
        <property type="protein sequence ID" value="CAD9603548.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S2LE40"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43302">
        <property type="entry name" value="TRANSPORTER ARSB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43302:SF5">
        <property type="entry name" value="TRANSPORTER ARSB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="239"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="316"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="399"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="528"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="573"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="605"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="Citrate transporter-like" evidence="8">
        <location>
            <begin position="153"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="Citrate transporter-like" evidence="8">
        <location>
            <begin position="477"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CAD9603548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1734827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="643" mass="70627" checksum="A8EDDCF749151D7D" modified="2021-06-02" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XS51</accession>
    <name>A0AAD8XS51_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Casein kinase II subunit beta</fullName>
            <shortName evidence="2">CK II beta</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_016372</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the casein kinase 2 subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XS51"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005956">
        <property type="term" value="C:protein kinase CK2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019887">
        <property type="term" value="F:protein kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1820.10:FF:000008">
        <property type="entry name" value="Casein kinase II subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.20:FF:000001">
        <property type="entry name" value="Casein kinase II subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1820.10">
        <property type="entry name" value="protein kinase ck2 holoenzyme, chain C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016149">
        <property type="entry name" value="Casein_kin_II_reg-sub_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035991">
        <property type="entry name" value="Casein_kinase_II_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000704">
        <property type="entry name" value="Casein_kinase_II_reg-sub"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11740">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11740:SF0">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01214">
        <property type="entry name" value="CK_II_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00472">
        <property type="entry name" value="CASNKINASEII"/>
    </dbReference>
    <dbReference type="SMART" id="SM01085">
        <property type="entry name" value="CK_II_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57798">
        <property type="entry name" value="Casein kinase II beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01101">
        <property type="entry name" value="CK2_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="213"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="219"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="249"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1732834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="344" mass="36966" checksum="B2B7F0B8F920F081" modified="2024-05-29" version="1">MAYNEDSSASGHDEPWIQWFCGLKGHEMFCEVERAYIEDGFNLYGLRACVSNFSDCLDLILDRIGPDDSDDSHLTKSACTLYGLIHARYIVTAHGLDSMYNKYAAKEFGTCPLIQCSGQPVLPVGLKDDIGLERVKIFCPKCQSVYHPPPIRSRGVHHSSNGGGGAVDGAAFGTTFPHLFLMTFNNLMPDPLPPDSSYTPKVFGFRVHKSAWQQGRGGYPSRSNNNNNSSRRGGAYTQRRLASMTTSRVAPAAPVQQQPAANAGKDGGAQDGRTGKPSVAVAGTGEASPQPVEAVKPESKETIPGVVVEEASANGNDSASKRKNKSDGSKNSVSPKRQKRSDAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XS55</accession>
    <name>A0AAD8XS55_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000063">
        <property type="protein sequence ID" value="KAK1732589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XS55"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="134" mass="14786" checksum="48E7CAD10DB872B8" modified="2024-05-29" version="1">MKLSQQAIDAEAARVKAANIKPLVWAKPTFEIDSPAADTATDDVAAAAAADETQAEEPQAEETQEADKLGKRKGSPTKPPQHYSPYHLERLSYKPRRKLTREEVQAFAEFTDKWMPSAKRISAGSGNDDEEESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTF1</accession>
    <name>A0AAD8XTF1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP-dependent Clp protease proteolytic subunit</fullName>
            <ecNumber evidence="12">3.4.21.92</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_016169</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 13">Belongs to the peptidase S14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.92" evidence="12"/>
    <dbReference type="EMBL" id="JATAAI010000053">
        <property type="protein sequence ID" value="KAK1733192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTF1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009368">
        <property type="term" value="C:endopeptidase Clp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051117">
        <property type="term" value="F:ATPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033135">
        <property type="entry name" value="ClpP_His_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018215">
        <property type="entry name" value="ClpP_Ser_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381:SF15">
        <property type="entry name" value="CHLOROPLASTIC ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00382">
        <property type="entry name" value="CLP_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00381">
        <property type="entry name" value="CLP_PROTEASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0934">Plastid</keyword>
    <keyword evidence="3 12 15" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0720">Serine protease</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="14">
        <location>
            <begin position="45"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1733192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="272" mass="29334" checksum="AFF22480AEA6A887" modified="2024-05-29" version="1">MAGASENGGDHIFLATNTYVLTMASNTAAPPVALHQENLPDDLVCSICLTVPADPLVTPCDHVFCEPCIRQALNHNNLCPIDRRPCCIGELNPIEGLSFRIWNGIQVKCGGHESVDDEIANVLCAQLLYLANEDPTKDITLYINSPGGSVSAGMAIYDTMQYVPCDVSTVCFGMAASMGAFLLGAGAPGRRRALPNARIMIHQPLGGAQGQAADIEIQAKEILFIREPKDKIEADCDRDFFMTAEEAVDYGIIDEMITTKTSHITKPPMPIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTI4</accession>
    <name>A0AAD8XTI4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sialate O-acetylesterase</fullName>
            <ecNumber evidence="5">3.1.1.53</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_015842</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.53" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000049">
        <property type="protein sequence ID" value="KAK1733427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTI4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001681">
        <property type="term" value="F:sialate O-acetylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005181">
        <property type="entry name" value="SASA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33683">
        <property type="entry name" value="1, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33683:SF46">
        <property type="entry name" value="SUSHI DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03629">
        <property type="entry name" value="SASA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042284020" evidence="3">
        <location>
            <begin position="30"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="domain" description="Sialate O-acetylesterase" evidence="4">
        <location>
            <begin position="168"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="356"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="365"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="401"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1733427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="609" mass="67756" checksum="2F39781164A1B511" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTW5</accession>
    <name>A0AAD8XTW5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MAPEG family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_016008</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000051">
        <property type="protein sequence ID" value="KAK1733291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTW5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006691">
        <property type="term" value="P:leukotriene metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.550">
        <property type="entry name" value="Membrane associated eicosanoid/glutathione metabolism-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050997">
        <property type="entry name" value="MAPEG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001129">
        <property type="entry name" value="Membr-assoc_MAPEG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10250:SF26">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10250">
        <property type="entry name" value="MICROSOMAL GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
        <property type="entry name" value="MAPEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="MAPEG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1733291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="151" mass="17120" checksum="3C61DC48C35D9FDF" modified="2024-05-29" version="1">MATIELTAEHGKCIAILILLWLQQQLVFAIAVAFARKKSGIDAPTLYPRDSEIKKLNLSEKDVDSYMCVQRVHQNNVEFLTCFFPVMLLAMIDYPTKTFYAGIVVLMGRMVTALGYYRGASKRVAGGWFHFGEYYVVYLAGKFAYKLINEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV66</accession>
    <name>A0AAD8XV66_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA (guanine(46)-N(7))-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_014976</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42708"/>
            <dbReference type="Rhea" id="RHEA-COMP:10188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10189"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.33"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.33" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV66"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043527">
        <property type="term" value="C:tRNA methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008176">
        <property type="term" value="F:tRNA (guanine(46)-N7)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003358">
        <property type="entry name" value="tRNA_(Gua-N-7)_MeTrfase_Trmb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417">
        <property type="entry name" value="3-DEOXY-D-MANNO-OCTULOSONIC-ACID TRANSFERASE/TRNA GUANINE-N 7 - -METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417:SF14">
        <property type="entry name" value="PENTACOTRIPEPTIDE-REPEAT REGION OF PRORP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02390">
        <property type="entry name" value="Methyltransf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51625">
        <property type="entry name" value="SAM_MT_TRMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="168"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="215"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="397"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="827"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="215"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="400"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="838"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="868"/>
            <end position="892"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1734469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="892" mass="98681" checksum="456D92A41E5595E2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVJ9</accession>
    <name>A0AAD8XVJ9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NAD-dependent alcohol dehydrogenase</fullName>
            <ecNumber evidence="8">1.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_014982</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.1" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000040">
        <property type="protein sequence ID" value="KAK1734215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVJ9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43350:SF2">
        <property type="entry name" value="GROES-LIKE ZINC-BINDING ALCOHOL DEHYDROGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43350">
        <property type="entry name" value="NAD-DEPENDENT ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="7">
        <location>
            <begin position="42"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="6">
        <location>
            <begin position="269"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1734215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="433" mass="47001" checksum="BB21A59F1D2314F4" modified="2024-05-29" version="1">MTTPLPTTMQAFVIDPKNHEDNPLDNGALITNHPLPTIPNEKYALVKILRAGICNTDLEILQGYMGFGGILGHEFVGKVIQLHPTASQSLHDQWIGQRVCGDINIGCCNFSSDNNSTESSNNDTSSTSSCRVCNNKFNYNQSNPQMSRNHCPNRTVIGILNQNGTFAEYMTLPLSNLHVVHESIPDEIAVFAEPLAAACRVVEQGLVQFRYSDGGGEECRGGDRVAILGDGKLGLCIAEILGREYLLAQQKQQEQQNGSGGIAPHAPILFGKHEHKLDLVSDSGVQRRLVKECYTDEMTQEEVVSPHHANQYDVVIDSTGNPNGLTLAMTLCRPMGRLVLKSTCAAGVKGFNSAPIVIDELNVVGSRCGPIDRALELLEGNSTEGVAENGVVVSAPLRMEKYITESFPLSRVRDALECAAKKSTMKVQLVMAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVT2</accession>
    <name>A0AAD8XVT2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014757</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000038">
        <property type="protein sequence ID" value="KAK1734509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVT2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="192" mass="20776" checksum="699509A5201C9AD8" modified="2024-05-29" version="1">MTGFECSNVYHSTENTVFTDMSFRPDYTGTLLGTFTSAQDYDDDIELTFEIQCPTTDDTIETTMDLCNNTYVSGVACGSEGVMTVDLSAYVEEYSTLNVMEGVVGCDVRASAPSGDLCLKTSQLKSVYENVEADPISAAEHVVAAVAIIGLAVFAGKRLVKEVRHRRGSTNCQCEMCKKGREGDHYQGGAIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWM1</accession>
    <name>A0AAD8XWM1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014089</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWM1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="413"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="208"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="634" mass="68521" checksum="7FA38BAD9E2AFC63" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYI6</accession>
    <name>A0AAD8XYI6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">magnesium chelatase</fullName>
            <ecNumber evidence="2">6.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_012836</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>protoporphyrin IX + Mg(2+) + ATP + H2O = Mg-protoporphyrin IX + ADP + phosphate + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13961"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:60492"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.6.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Porphyrin-containing compound metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mg-chelatase subunit H family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.6.1.1" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016851">
        <property type="term" value="F:magnesium chelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10150">
        <property type="entry name" value="CobN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011771">
        <property type="entry name" value="BchH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003672">
        <property type="entry name" value="CobN/Mg_chltase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022571">
        <property type="entry name" value="Mg_chelatase_H_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02025">
        <property type="entry name" value="BchH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44119">
        <property type="entry name" value="MAGNESIUM-CHELATASE SUBUNIT CHLH, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44119:SF1">
        <property type="entry name" value="MAGNESIUM-CHELATASE SUBUNIT CHLH, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02514">
        <property type="entry name" value="CobN-Mg_chel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11965">
        <property type="entry name" value="DUF3479"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0149">Chlorophyll biosynthesis</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042170105" description="magnesium chelatase" evidence="12">
        <location>
            <begin position="29"/>
            <end position="1848"/>
        </location>
    </feature>
    <feature type="domain" description="Magnesium chelatase subunit H N-terminal" evidence="14">
        <location>
            <begin position="101"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="CobN/magnesium chelatase" evidence="13">
        <location>
            <begin position="268"/>
            <end position="1447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1564"/>
            <end position="1584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1818"/>
            <end position="1848"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="1747"/>
            <end position="1774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="77"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1818"/>
            <end position="1835"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF11965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1736236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1848" mass="203609" checksum="EE01BC6DDFD1AF1E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYJ4</accession>
    <name>A0AAD8XYJ4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Serine aminopeptidase S33 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013233</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYJ4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="1">
        <location>
            <begin position="4"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="107" mass="11968" checksum="4238A53610DD4906" modified="2024-05-29" version="1">MIAHTAIATDKAFDYAKQRRGEIYCPTLMLHSPDDKCTSQKASEDFFANIGTALEDKRYLKLNGMYHETLEEPETERIVKSIVTFVASGGKEFVEDVGNGGVVEMFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZY4</accession>
    <name>A0AAD8XZY4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZY4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3110">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="238" mass="27428" checksum="63E5309D965ACA56" modified="2024-05-29" version="1">MDLFSQRRASTASSVSTTSSPVRTKALSEQHRQLTEKLIRLKFEIAEQKGKHGELQFDWQKLNSEKHSIHSEIVEAEKECASIRDETDQIRVEQTRRKQRLDQLVADNLPERRAADEVQDEHDKTQSELQATKEEIQNVKAAGEKLHKTIEDLKEHAAEISSERVKISAQSDEVKSEIETLKKEIVAMRSSVQNTKEKSDQYETDLIEARKENVLLAKQNDVLESKIAAREEYLEKHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1J9</accession>
    <name>A0AAD8Y1J9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Serine/threonine-protein kinase</fullName>
            <ecNumber evidence="9">2.7.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_011585</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1J9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000026">
        <property type="entry name" value="Calcium/calmodulin-dependent protein kinase type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="19"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1737813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="337" mass="37919" checksum="CF1A97AACD77F864" modified="2024-05-29" version="1">MGSTPRPDSSSGLSFDELYSLSETLGSGAFSVVKRGTHTRTPTTSYAIKCVTRSKLTREDTLALKDEVSILSQLRNCKHIIRLYDFFEESKMFYLVMECVMGGELFDRIVEKSYYNEKEARATCRILLEAIGYCHEHGVAHRDLKPENLLLRSKEDDSSIKIADFGFAKIVEGKGSLKTQCGTPGYVAPEILNGKPYDESADMWSVGVILYILLGGYPPFIEDDQRRLFRKIRKGQYEFHEEYWGSVSEDAKNLISNLLCVNAENRLTASEALQSNWISAATDAELGAIDMESNLHQLRKFNGKRKFRAAVASVIAANKLKNFLAFDQFQPGCAVNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1Q3</accession>
    <name>A0AAD8Y1Q3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine-protein kinase</fullName>
            <ecNumber evidence="4">2.7.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_012133</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1Q3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043539">
        <property type="term" value="F:protein serine/threonine kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047173">
        <property type="entry name" value="STRAD_A/B-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48014">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE FRAY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48014:SF21">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE FRAY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="89"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="438"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="520"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="520"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="534"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="550"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1737266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="579" mass="63870" checksum="5951E24765DB43E6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2Z4</accession>
    <name>A0AAD8Y2Z4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Oxidized purine nucleoside triphosphate hydrolase</fullName>
            <ecNumber evidence="13">3.6.1.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">2-hydroxy-dATP diphosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">7,8-dihydro-8-oxoguanine triphosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">8-oxo-dGTPase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19">Methylated purine nucleoside triphosphate hydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Nucleoside diphosphate-linked moiety X motif 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">QTG54_011364</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="25" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="25">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="23">Oxidized purine nucleoside triphosphate hydrolase which is a prominent sanitizer of the oxidized nucleotide pool. Catalyzes the hydrolysis of 2-oxo-dATP (2-hydroxy-dATP) into 2-oxo-dAMP. Also has a significant hydrolase activity toward 2-oxo-ATP, 8-oxo-dGTP and 8-oxo-dATP. Through the hydrolysis of oxidized purine nucleoside triphosphates, prevents their incorporation into DNA and the subsequent transversions A:T to C:G and G:C to T:A. Also catalyzes the hydrolysis of methylated purine nucleoside triphosphate preventing their integration into DNA. Through this antimutagenic activity protects cells from oxidative stress.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2-oxo-ATP + H2O = 2-oxo-AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67392"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:71395"/>
            <dbReference type="ChEBI" id="CHEBI:172878"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:67393"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>2-oxo-dATP + H2O = 2-oxo-dAMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:31583"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:63212"/>
            <dbReference type="ChEBI" id="CHEBI:77897"/>
            <dbReference type="EC" id="3.6.1.56"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:31584"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>8-oxo-dATP + H2O = 8-oxo-dAMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:65396"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:71361"/>
            <dbReference type="ChEBI" id="CHEBI:172871"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:65397"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>8-oxo-dGTP + H2O = 8-oxo-dGMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:31575"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:63224"/>
            <dbReference type="ChEBI" id="CHEBI:77896"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:31576"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>N(6)-methyl-ATP + H2O = N(6)-methyl-AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67608"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:144842"/>
            <dbReference type="ChEBI" id="CHEBI:172873"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="20">
            <dbReference type="Rhea" id="RHEA:67609"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>N(6)-methyl-dATP + H2O = N(6)-methyl-dAMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:169976"/>
            <dbReference type="ChEBI" id="CHEBI:172872"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="22">
            <dbReference type="Rhea" id="RHEA:67605"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>O(6)-methyl-dGTP + H2O = O(6)-methyl-dGMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67600"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:169974"/>
            <dbReference type="ChEBI" id="CHEBI:169975"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="21">
            <dbReference type="Rhea" id="RHEA:67601"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.56" evidence="13"/>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2Z4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008413">
        <property type="term" value="F:8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008828">
        <property type="term" value="F:dATP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042262">
        <property type="term" value="P:DNA protection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03427">
        <property type="entry name" value="NUDIX_MTH1_Nudt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003563">
        <property type="entry name" value="8ODP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43758">
        <property type="entry name" value="7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43758:SF2">
        <property type="entry name" value="OXIDIZED PURINE NUCLEOSIDE TRIPHOSPHATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01403">
        <property type="entry name" value="8OXTPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 25" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="24">
        <location>
            <begin position="88"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00026103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00026218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00029673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00030634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00030682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00031927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00032071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00048894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00049032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00053094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="KAK1738070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="276" mass="31682" checksum="79D9233AD6AB084B" modified="2024-05-29" version="1">MMLRPSEMFIKLPCRRISQTYAVKTSRTKLVAAPTSRQYIICRLFSNTSASDDRFMYKQPPSRLGICHPSLTSYLSATGNNITNDAKEVESSTLIILTNINERKLLLGKKLRGFGTGKYNGFGGRLEREETPAHCAKRELMEEANLSIDLDEFVIGSVGTLNFTFQDREHIEMLVHLFHINVHFRNATHNTCKGTIIDPDAIRACDEMIPEWFDWWEIPLHQMFADDSIWLTYYLSSLDARRDKRSHASLPKMNGWFHFAPGGDGNNQILHYFLDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y322</accession>
    <name>A0AAD8Y322_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">CAAX prenyl protease</fullName>
            <ecNumber evidence="14">3.4.24.84</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">QTG54_010668</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Proteolytically removes the C-terminal three residues of farnesylated proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 14">
            <text>Hydrolyzes the peptide bond -P2-(S-farnesyl or geranylgeranyl)C-P1'-P2'-P3'-COOH where P1' and P2' are amino acids with aliphatic side chains and P3' is any C-terminal residue.</text>
            <dbReference type="EC" id="3.4.24.84"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="13 14">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Endoplasmic reticulum membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the peptidase M48A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.84" evidence="14"/>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y322"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07343">
        <property type="entry name" value="M48A_Zmpste24p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2010.10:FF:000002">
        <property type="entry name" value="CAAX prenyl protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.10">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027057">
        <property type="entry name" value="CAXX_Prtase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032456">
        <property type="entry name" value="Peptidase_M48_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10120">
        <property type="entry name" value="CAAX PRENYL PROTEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16491">
        <property type="entry name" value="Peptidase_M48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 14 18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 14" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 14 18" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7 13 14" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="176"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="251"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="364"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="CAAX prenyl protease 1 N-terminal" evidence="17">
        <location>
            <begin position="116"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M48" evidence="16">
        <location>
            <begin position="286"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="76"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="76"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="354"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="12">
        <location>
            <position position="440"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="353"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="357"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="436"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR627057-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR627057-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU366005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF16491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1738638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="500" mass="56471" checksum="F631E87516C2E27C" modified="2024-05-29" version="1">MDFTLPLTPQYTQTGGTTKAASSSLFGDYAIAATILFTLVVFLFEAYLNFRQRKSYHKTDFPRELETTVGNIDRETKSSAAAADKKEESSKSGSSDDDDKKDKVDRNAPILPQLKSKFSHAQSYGLDKINFSIFSSTYAVTEEVVFLLYGFLPYVWDKACAVGAKYGWTETEHEIKITLLFLGIVTIVGTITSLPFELYSTFEIEKKHGFNKQTLGLFFTDKLKGLVLSAVFGAPFVALLLKIIFMGGDKFYLYVWAFTFVFSVIMMTLVPVVIMPLFNKYEKLPDGPLKDSIYELAGKLSFPLTKLFVMDGSKRSSHSNAFMFGFMKNKRIVLFDTLLSQVSNDEILAILGHELGHWKMGHTVTNFVVTQVYTGFMFYFFSLCYNSHELYRAFGFDDESRPIPTIIALVLFTSTIWAPVDKTLSFIMTVHSRKCEFEADEFSVNLGMSSKLQSGLCKIHLENLGAMSPDSWYSTYHYSHPPLVERLSAMMKLDTAKKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3M7</accession>
    <name>A0AAD8Y3M7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_010633</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3M7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1738603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="62" mass="7219" checksum="C9A12BB8CCC5624F" modified="2024-05-29" version="1">MIPYFFLMNALGIFLVEQSKKKLFWISLTTSHKGSAYDLTEYNESSPIADKYIPLQLQTRKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y481</accession>
    <name>A0AAD8Y481_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pre-rRNA-processing protein TSR2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_010799</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TSR2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y481"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019398">
        <property type="entry name" value="Pre-rRNA_process_TSR2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21250">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN TSR2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10273">
        <property type="entry name" value="WGG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="135"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="139"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="178"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1738769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="243" mass="26471" checksum="DF928819A4075841" modified="2024-05-29" version="1">MSAEDNNNPYTSFQAGVTATLRTWSALKTAVDQTWGGTESATKAEDLRRTIFSYFDGQSPNPKMTLYELEDNLGAYMEEEFGVVLEDESEREVADLIWRMYECCAKGDCALANQVVMDAIQAEELLKKSEVKSVIKNGDDDDDDDDDAMNDSSEEQEIGGDDNDDAMNSSSTTPKNEATAAAATAPTSALEYSQGYLFGGPPKPKKELPPPRQLGEAAPETPMPVIDDDGFAPVVTKKKGARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4C9</accession>
    <name>A0AAD8Y4C9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4C9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="163" mass="17737" checksum="42587DE8BA816082" modified="2024-05-29" version="1">MSHQNVKHEPEQPSSSIEAHDLSEAQGKDDYEGDGFGVIKYKLLRGKGEGGKSSANPFTTIGSGALVAAFLLLLSCCLCCLRYRRRRYAQSKRPSRGNYAALGRHDFFNGTFSDDVSYGKDSDDDISIESYGSDDGGHQTNLEMGGFHEFDANGGLTLEEING</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4L5</accession>
    <name>A0AAD8Y4L5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4L5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="1">
        <location>
            <begin position="77"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="618" mass="69555" checksum="1D4DEE71FED9417F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4V5</accession>
    <name>A0AAD8Y4V5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heat shock factor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_010725</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4V5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000479">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF206">
        <property type="entry name" value="HSF-TYPE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="6">
        <location>
            <begin position="123"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="64"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="96"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1738695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="369" mass="40896" checksum="ECC77981A65820DA" modified="2024-05-29" version="1" fragment="single">RDHVTSILLPIVSCSSNPHKSTSIISSRVFLQMKSSTNDNSNVMSGAVTSTGLDLLFAASQLTTTSSGGADPNDHHRPSLPVNNVQYSYPPPRDAASTSNNQDVAAPSNNDGGDVYSPVVDNSAKSFVQLLMDILNVPDPDHASIICWVPDGKSFLIADQERFETELLPTYFRGSMFNSFVRKLNRWGFRRLKRTGHASSFAHDLFVRDKPWLCGRMRCQSKPNFKKVPTKVTDDVRQSAFDAATDVAIPPCVDVQHAAPSTSSGLYSNINVTQPLSTLQPPLSTTVPFDVTKIPSSPIEERLRRELLFASITQMQQRPLSQMPQLQMNPNQLQYLNNISALTDEALAPRYLQPSSMSQYTRDLLRRNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y4Z4</accession>
    <name>A0AAD8Y4Z4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_010475</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y4Z4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006691">
        <property type="term" value="P:leukotriene metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.550">
        <property type="entry name" value="Membrane associated eicosanoid/glutathione metabolism-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050997">
        <property type="entry name" value="MAPEG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001129">
        <property type="entry name" value="Membr-assoc_MAPEG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10250:SF26">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10250">
        <property type="entry name" value="MICROSOMAL GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
        <property type="entry name" value="MAPEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="MAPEG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="112"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1739159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="196" mass="21170" checksum="872BDEF1C28523FD" modified="2024-05-29" version="1">MTTKPLLICLSTASIGGFLELTTASKFTSSHHQSQLTAITPCILIGTGLWTLAHGFTVGKARIKYAALAKKDGETNVDERYLLPNLYAQGTSKHVRAFNCIQRSHQQIFETYTTVVLSGVMGAISFPICTAVSTFVYAVGRYQLSTGYAEAAEEGGDASKRYKYPLAKFMWYGFLCNVLLGMGSCGLIIGGKKTVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y556</accession>
    <name>A0AAD8Y556_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009658</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y556"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="553" mass="61453" checksum="B4EDFAC012B9F84F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5H4</accession>
    <name>A0AAD8Y5H4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5H4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1739862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="195" mass="21854" checksum="F787356CFB374B63" modified="2024-05-29" version="1">MSTQQPSKKRTLAAAAEALVEAASLEADSMTQKQLAQNLDSLKASFDSNLNRVVQSVKSSNEAFDAKINTLNQHVAGVKDEIVALKSLLKEETKQKTLERALSLTDIDSFEYYPSRSYQKSNSGELVKKAIKWFMLGSGMILSSDYCMKQNVYGNEATTSNEDFRAKFIEQIKTLIKREPRVEKQSNGNFAIYYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5K6</accession>
    <name>A0AAD8Y5K6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">2OG-Fe(II) oxygenase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_009666</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5K6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031543">
        <property type="term" value="F:peptidyl-proline dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071456">
        <property type="term" value="P:cellular response to hypoxia"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051559">
        <property type="entry name" value="HIF_prolyl_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12907">
        <property type="entry name" value="EGL NINE HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12907:SF26">
        <property type="entry name" value="HIF PROLYL HYDROXYLASE, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0847">Vitamin C</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041927187" evidence="7">
        <location>
            <begin position="24"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="8">
        <location>
            <begin position="155"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1739907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="388" mass="42980" checksum="84DF2D8D761E8EB9" modified="2024-05-29" version="1">MVTGRRSSLLAAIAVVYLKTCCALSSNTAAATTTTTTNSCSSPLISTEDIQKISQGGVAIIPNWLPPHLITAMHDDAQQLFQDGQFRPDGLTNTAIKEQGFSKKADRQTFRGGAGWDSDIGDLKTRQEFADRMKELRIQLAQSLNRPTLAEDGTLKHEMTYNWYEPGAKLGRHLDEHHEETKGPTGWMTPTRRSVTWLVYLNEGWTKEEGGALRCLPRSDASIQKNTVQVGCHEGNLQVGWINDGVDPVFLDVFRESGGAALYQVNNNNAEREILSVRDFDVPAQPIDFSKFLKEDIRESFAQISTSRLDPRFANKDAAANNNNGAIAQHDFECSDEPTILDVTPVAGTLVVFDSVSLPHLVREVTGKRQRIAATGWFHEDSQFSIEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y612</accession>
    <name>A0AAD8Y612_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_009446</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y612"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48032:SF6">
        <property type="entry name" value="RNA-BINDING (RRM_RBD_RNP MOTIFS) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48032">
        <property type="entry name" value="RNA-BINDING PROTEIN MUSASHI HOMOLOG RBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="34"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="157"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="112"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1739687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="335" mass="36224" checksum="6FA49B05FBC0329A" modified="2024-05-29" version="1">MSYYGNGGGDDASNTPHHSFHKPATNAPSQIDAAKIFVGGLSWQTTEETLRYHFEQYGEVVSVEVMRDRQTGDPRGFAFVVFTSDETVDLILKGCPHEINQKVVDVKRAQARGVAPPSIHHGGEEESVASGGQQQHSVKQERHNNSTTGLSPEQLRNKIFVGGLPMHCDKDGLKEFFSVFGPVVDAIVMMDTVNQRSRGFGFVTFENGSGGAQKAIEVQPINMFGKSVEVKLATPKADRDGGGGGGGNFQQKHFQQKQVMAPSASNTGEFAGLASAYGRAGWRAGYGSKAFGKAGWSVIGWDDGGDAPDKKGFSFALLDSKRDSGEHRESKRRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y625</accession>
    <name>A0AAD8Y625_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008486</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y625"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39444">
        <property type="entry name" value="SITE-SPECIFIC DNA-METHYLTRANSFERASE (ADENINE-SPECIFIC)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39444:SF3">
        <property type="entry name" value="SITE-SPECIFIC DNA-METHYLTRANSFERASE (ADENINE-SPECIFIC)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="316"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="367" mass="42410" checksum="F053436662D1F3D8" modified="2024-05-29" version="1">MASLPPTNTIMTDNKPQPQQHPPNQQWASLADRLNPNRPAFDAQLKSSWKTLSKKEKKRIITQDRKAIQALKSRGTSHSLPFEADTDDHCETSHVAYAHIAPILTYIAEQIGTTPSNLRIYDPYYCAGTVVQHLNKLGFENVYNQPEDFYQVIRDGCVPQHDVLLTNPPYSGDHFERLLKFCSENNKPALLLIPDHLSKKKYVRDYQEKYFFLTPAERYFYWTPEGLRPNEGNDGDDQKKSKKEKKSNQHKNLMLGTRNSPFASHWFICTNPLLPNKKVISLIQREEIKLLDGCNVFDRHEDIVQSNSFRKRKEIEQNESKVECEEHQQEEEGQRKGRKKKKKRVQKEKCAPVNGGTDAVDGSNPFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6B6</accession>
    <name>A0AAD8Y6B6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypoxia-inducible factor 1 alpha inhibitor-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008636</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6B6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF105">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1-ALPHA INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="1">
        <location>
            <begin position="127"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="292" mass="33462" checksum="97374A09A552B688" modified="2024-05-29" version="1">MWQRYSVAVRRLSFSSSQHQIKSKPIETISLPQLSSQDINSHEHQLAIADAIRPYHQSQTPLLLTNLNSKCDAIYFWRSIQYWQAAVPENTPVDVELGRSYNTGNRVSMKFGDYLDYLSKVTEQEEKDAEQQEEVAYLAQNELFAEVRNDIPTPHFCSDGSFNVGEGKLYHSMLWLGPRGTVSPLHYDPLDNLLMQIVGNKRVLLYPPDKGNGRDNNNSGSWHYAGLNGNQYNTSAVDVENPNFEEHPNFQSAPTPYECEIGPGDLLFIPSKWWHHVRSFSKWSASANVWWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6D6</accession>
    <name>A0AAD8Y6D6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">AP2/ERF family transcription factor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_009704</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6D6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32467">
        <property type="entry name" value="AP2-LIKE ETHYLENE-RESPONSIVE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32467:SF90">
        <property type="entry name" value="AP2-LIKE ETHYLENE-RESPONSIVE TRANSCRIPTION FACTOR AIL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51032">
        <property type="entry name" value="AP2_ERF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="83"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="233"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="319"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="374"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1739945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="400" mass="44589" checksum="FB911E0FD620416C" modified="2024-05-29" version="1">MDREQSDSEDSEDDGKICGATADEYFLDDEVGKKRDCPLEDSISNNKTKKRQRVDAFVIDLSDVPPQSPIPKSSGCVKEGASKYTGVSFDKRMNKWHAQIMIAGKSRNIGYYENEEEAAVDYARALFKYKGQGALDKARERRALDKEREQNGEICGVTTAVKGLCDRHSTHGNKYGLDNEVGKKRALTSGGSIGGNKTKKCKKVDAFVLDLTGVPPQSPIPKSGGHIKEGASKYKGVHFNKQKNKWQAKLGIEGKNRHIGYYDNEEEAATDYARAVFKYKNQAALGKAREDSFIIDLSDVPPQPPIPKSSGTIKEGASKYTGVHFNKQANKWRVQIDIKGKYRTIGHYENEDEAATDYARAVFKYKNQAALDYAAQRSRGTRQSKETKSIRRSNGAEFNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7C6</accession>
    <name>A0AAD8Y7C6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7C6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="1">
        <location>
            <begin position="47"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="267" mass="29878" checksum="83A0076AA5FCBEBC" modified="2024-05-29" version="1" fragment="single">GGLSPGGSSIAALIRDEIQNEFDKDDLEQLRRVLPECAEILGTRRTSLFCSSSQAQADKAAFCRGGSGSRLGSFSLNLLGGKESISRMHFAVRRLLKIVCSHFKGVVLFIDDLQWSDTATLDLLKSIVLDGEIPSLLIVGAYREDEVPDHHPLAFHIRELEEMKVSITKIKIGNLSVDYAIPLVAEALGMDDDDSKVKSLADTIHRKTEGNPFFMLMFLRSLYDEKLLQFNFGVMKWTWDEDEVKSKIVTENVASVLVEKMNRLQEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7R1</accession>
    <name>A0AAD8Y7R1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_007814</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7R1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1741336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="125" mass="13658" checksum="507AF529FF29E9AB" modified="2024-05-29" version="1">MAEGNMSMSDLLPLVAAALNDEAAADAAKELATAREERDMSHKVEVLRAINDGDDKVYEDGETIVYGSALFEDGQYHSRNEDDWKIQLNKSRNICRLEDLRDCHICVGGGIAIASLDETTVATKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7V7</accession>
    <name>A0AAD8Y7V7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7V7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="674" mass="74950" checksum="38C57C3E9D955E38" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7V8</accession>
    <name>A0AAD8Y7V8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Complex I intermediate-associated protein 30</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_007907</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CIA30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7V8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010257">
        <property type="term" value="P:NADH dehydrogenase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013857">
        <property type="entry name" value="NADH-UbQ_OxRdtase-assoc_prot30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039131">
        <property type="entry name" value="NDUFAF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13194">
        <property type="entry name" value="COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13194:SF19">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08547">
        <property type="entry name" value="CIA30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042222320" evidence="3">
        <location>
            <begin position="24"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="NADH:ubiquinone oxidoreductase intermediate-associated protein 30" evidence="4">
        <location>
            <begin position="126"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="42"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1741429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="291" mass="32111" checksum="B5728D19FFFD7EE4" modified="2024-05-29" version="1">MATFRSISCLLALLLCLFDSSEALLTPFSAQQNMSRVGNRHHHPYISTRHVTKTTPSNHISRREGKRSHHQSSTSLAAADERKPWELFRFISQSSKFVTLPPLPFAAKNPVTRKVGVGETIWEAGNPNNFFNFAPLDDVVMGGASNSNIDNNTGTWSGKVTDANNGGFVGVRSTPFQGGSLSLDMSQCKGIEIRFRRGNGKRFKFVVRDSTEFNGICWTTSFDAKANGSVRIPFSSQVPTVFAKTVSGASFNVDEVVGLQFAYSKFEYDGKLNNNFDVGDFALQIVELKTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7W8</accession>
    <name>A0AAD8Y7W8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_007904</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7W8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1741426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="617" mass="71552" checksum="C16C47CD078B6457" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8A9</accession>
    <name>A0AAD8Y8A9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pirin family protein</fullName>
            <ecNumber evidence="5">1.13.11.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_007242</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the pirin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.24" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8A9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008127">
        <property type="term" value="F:quercetin 2,3-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02247">
        <property type="entry name" value="cupin_pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008778">
        <property type="entry name" value="Pirin_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903:SF8">
        <property type="entry name" value="PIRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903">
        <property type="entry name" value="PIRIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05726">
        <property type="entry name" value="Pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin N-terminal" evidence="3">
        <location>
            <begin position="67"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin C-terminal" evidence="4">
        <location>
            <begin position="254"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1741669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="379" mass="42501" checksum="23FFC5A7F8C59D07" modified="2024-05-29" version="1">MGETIPSPPPQASAQRGVARIEKFARLPVWPVWQGVFLFFASKIFGEEVAAGWENRIGGRVCPNFLTAEATSPFVLLVHHRHSFSNWDPVKYIQQTFFPEGFPSHPHRGFITVTYCLKGGMVHRDSLGIKQSYGAEKRHGSKHVQWLTAGAGIQHEEMWDIEPDTQDEGKLLWSSSQELYQLWINMPSDYKMSKPNAELLEAYPVASSTSSSTIPDNTTPVVKENNDATTTTVVAGEYKGIRAPVDCPTNVSMMRVQLSKDSSWTHNIPSSHETAIIYVRNGSIQIGTQRIPPHYTVYLTSQGEELSIQSLEGEADILLLSGEPLREPIASQGSMVMNTQPEIQQAYLDYQLGKMGLPWSEKLSDEEWQQHVKRNPSLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8T0</accession>
    <name>A0AAD8Y8T0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008319</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8T0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd19671">
        <property type="entry name" value="UBR-box_UBR4_5_6_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="489"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="581" mass="64180" checksum="5AE32B720E6E5FBE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y927</accession>
    <name>A0AAD8Y927_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Fucoxanthin-chlorophyll a-c binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">QTG54_008253</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated. Energy is transferred from the carotenoid and chlorophyll C (or B) to chlorophyll A and the photosynthetic reaction centers where it is used to synthesize ATP and reducing power.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast thylakoid membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fucoxanthin chlorophyll protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y927"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030076">
        <property type="term" value="C:light-harvesting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3460.10:FF:000011">
        <property type="entry name" value="Fucoxanthin chlorophyll a/c protein 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 15" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="5" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="10" id="KW-0157">Chromophore</keyword>
    <keyword evidence="13" id="KW-0437">Light-harvesting polypeptide</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="14" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042229091" evidence="16">
        <location>
            <begin position="17"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1741001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="200" mass="21430" checksum="416BE4D0BA6407AC" modified="2024-05-29" version="1">MMKTAILATLAASAAAFAPAQTGKAATALNAFENELGAQPPLGFFDPLGLLDEAGQGRFDRLRYVEIKHGRICQLAFLGNIITRAGVHLPGNIATDGTKFSDVGNGWAGSFDVPVDGALQILFFVGFLELFVMKDVTGENEFVGDFRNGFIDFGWDSFDEETKLKKRAVELNNGRAAMMGILGLMVHEQLGGSLPVVGEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YA92</accession>
    <name>A0AAD8YA92_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YA92"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="191" mass="21395" checksum="FBEC5014AF7C6254" modified="2024-05-29" version="1">MQDVMVMKGTEDEYGSILSMGNKSDSSETETSIIMQGLNSRGGGPNLHHNIPPSHPQPSSTIRSPTPTAIQFKFNATNQTLASDFDRLLENKNYYRDPLDDNKSILSKECLRQGNDKEPNKDKAEVIGCSEFDDDDNDKGFSPSDCGNATGYKFCQLECSFPDMFEDVNETLSNDLHNLKLSQERERQGMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAD6</accession>
    <name>A0AAD8YAD6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Subtilisin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006388</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAD6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33683">
        <property type="entry name" value="1, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33683:SF46">
        <property type="entry name" value="SUSHI DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042177744" description="Subtilisin" evidence="2">
        <location>
            <begin position="21"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="261"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="354" mass="37629" checksum="FEB266474845D420" modified="2024-05-29" version="1">MKYFSTLLTLALTRTDIVLAQSVSAGFGGSSQADGNMFEIAAKDQPVLIERLDINMGASTEPVQVYYRTGYVDYRYDDSYTLIFHGDITGAGQGLATPLPPFTSPVLVTPGTPITIYVTVTNHDGANVYADVGTGSGTTYASDDNINIIEGMTSGYPWRGYALDRRWNGVVHYSLQANSSPTESPTISLNTPNPTNQPTNQPTNQPTKSPVVAVTQSPTASPVTPITSPPTVSTPHPTASPVVIRTGSPSNIVDDVGVVEAPTPATTNKPTTTDSASTKSPTTSSTKRTGTQDPKEPTDEPSPSPTVDESFAPTKTVTNLLPNFDPSSASNRFNFMGRVCSYSFPLFIIAFFVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAI9</accession>
    <name>A0AAD8YAI9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ISXO2-like transposase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAI9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="542"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="586" mass="64062" checksum="EE7A8680494D0E7B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAX6</accession>
    <name>A0AAD8YAX6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial</fullName>
            <ecNumber evidence="16">1.3.8.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">2-methyl branched chain acyl-CoA dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">2-methylbutyryl-coenzyme A dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="31" type="ORF">QTG54_007298</name>
    </gene>
    <organism evidence="31 32">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="31" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="31">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>(2R)-2-methylbutanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = ethylacryloyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:65296"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:156439"/>
            <dbReference type="ChEBI" id="CHEBI:156440"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="22">
            <dbReference type="Rhea" id="RHEA:65297"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="25">
            <text>(2S)-2-methylbutanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-2-methylbut-2-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:48256"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57337"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:88166"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="25">
            <dbReference type="Rhea" id="RHEA:48257"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>2-methylbutanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-2-methylbut-2-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:43780"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57336"/>
            <dbReference type="ChEBI" id="CHEBI:57337"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="1.3.8.5"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="20">
            <dbReference type="Rhea" id="RHEA:43781"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="26">
            <text>2-methylpropanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = 2-methylpropenoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:44180"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57338"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:62500"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="26">
            <dbReference type="Rhea" id="RHEA:44181"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="23">
            <text>butanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:24004"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57332"/>
            <dbReference type="ChEBI" id="CHEBI:57371"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="23">
            <dbReference type="Rhea" id="RHEA:24005"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="24">
            <text>hexanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-hexenoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:43464"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:62077"/>
            <dbReference type="ChEBI" id="CHEBI:62620"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="24">
            <dbReference type="Rhea" id="RHEA:43465"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>valproyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-2-propylpent-2-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:65344"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:156457"/>
            <dbReference type="ChEBI" id="CHEBI:156458"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="21">
            <dbReference type="Rhea" id="RHEA:65345"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 27">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="15">Amino-acid degradation; L-isoleucine degradation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; mitochondrial fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 27">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="31">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.8.5" evidence="16"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAX6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003853">
        <property type="term" value="F:short-chain 2-methyl fatty acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046395">
        <property type="term" value="P:carboxylic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.540.10:FF:000012">
        <property type="entry name" value="Acyl-CoA dehydrogenase short/branched chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000002">
        <property type="entry name" value="Acyl-CoA dehydrogenase short/branched chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000001">
        <property type="entry name" value="Acyl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884:SF1">
        <property type="entry name" value="SHORT_BRANCHED CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0007">Acetylation</keyword>
    <keyword evidence="8 27" id="KW-0274">FAD</keyword>
    <keyword evidence="9" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="7 27" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12 27 31" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="32" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="30">
        <location>
            <begin position="68"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="29">
        <location>
            <begin position="183"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="28">
        <location>
            <begin position="294"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00037895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00039036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00039850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00041537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00042821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00048307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00048592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00049096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00049192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="ARBA" id="ARBA00049552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="ARBA" id="ARBA00051903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="27">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="28">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="29">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="30">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="31">
        <source>
            <dbReference type="EMBL" id="KAK1741725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="32">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="445" mass="49050" checksum="9E4978B400A842B4" modified="2024-05-29" version="1">MTSACRAALRAASSMQRTITSASSSAARQNIRCTVTQTSRNFSASVVYPDISIEHSYEQRRLPVTQFTEDEEMVRDGARHWANEVLRPLVRDMDNEGKTRPDVIQGLFDHGFMGMEIPEEYGGSEMNFTSACLVVEELSRVDPSVSILVDIHNTLTNNAVRFWGSKELKEKWLPRLASEAVSSFALSEAGSGTDAFALKTTATASSDGSYYTLNGEKLWISNSREAGVFLVFANVNPSLKHKGITAFMVDANTEGLHVGKPEKKLGLRASSTCPVVLDNVKVDAADVLGEVGLGYKYCINILNEGRIGIASQQIGIAKGCMDIAMPYLNERSQFGTKLADFQGMEHQYAQIATEIHAAELMTYNTCRMKENDIPFVKEASMAKLYASQVAEKAASKSIEWLGGIGFTQDLLAEKFYRDCKVGSIYEGTSNIQLQTIAKRIKDEYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAZ5</accession>
    <name>A0AAD8YAZ5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_006978</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAZ5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000011">
        <property type="entry name" value="Putative ABC transporter ATP-binding component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF14">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="19"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1742413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="365" mass="41412" checksum="90C17AFE9303285F" modified="2024-05-29" version="1">MLSNSSNENDPQWQNSLDINIPSFTISAAGKVLFKDAQFNISHGRRYGLVGPNGKGKSTLLKMIASKDLILPPRVDFLYVEQEVEADNTPAVDAVLRADKIRWNLLEEEKTLSAAIDAGDEDPKKFSRLQEVLDELNTIGASAAEAKARRILFGLGFDGEMQTKPTKMFSGGWRMRISLARALFIEPTLLMLDEPTNHLDLDAVIWLDNYLLGWKKTLLIVSHDQDFLNSVCDEILHIEDLKLASYRGNYDSFKKAEATKLKQQQKDWEKQESVYVNSNVRAILRQRQRRRSKRTSVSRVHVVLRNKGSYCIGQDTAAMKELIKRPRDTLFKSTFQMLRAFAPSDGGEPGCLQILRETSCHFQPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YB97</accession>
    <name>A0AAD8YB97_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006579</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YB97"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056453">
        <property type="entry name" value="HTH_DNAJC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052594">
        <property type="entry name" value="J_domain-containing_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44144">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44144:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23302">
        <property type="entry name" value="HTH_DNAJC9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="16"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="371" mass="42463" checksum="AA02635B32184C96" modified="2024-05-29" version="1">MTVISLVKSAFGRKATLYTPLNCTKTSSESDLRSAYKKAALRFHPDKANANNSRDNNFDGDTTLKFQAVSAAYQVLMDEKQRAAYDATGQVLDEHDYDTGDEGNQQQVPRRKGKRPRNQKQQQWEDFFHSVFNEIISTGSQYENDAKMYSGSVQEHHDVLKYYNMCRGNMQKVLECVVHATQEDLSRWRKDIIDPAIYRGEVDDFLNNVNATTTKVLPKDVKKNHFTTPTSEDDTISTVKRSSSKLKRPKRGRDIFKKKSSCLVDTDDEFEQCNVVANKLPRQKNKAKTNSTTMSMREKMDYRVAKKRKIKAAKEMEIAKIVQSKTWDGGSNNHVYGNQERNKNRGGVSDQLLSQIERKYAAKSKSGRRNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBB6</accession>
    <name>A0AAD8YBB6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF3684 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006609</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1743012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022155">
        <property type="entry name" value="DUF3684"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058210">
        <property type="entry name" value="SACS/Nov_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47839">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G04830)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47839:SF1">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G04830)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12449">
        <property type="entry name" value="DUF3684"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25794">
        <property type="entry name" value="SACS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sacsin/Nov" evidence="2">
        <location>
            <begin position="29"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="448"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1473"/>
            <end position="1530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1565"/>
            <end position="1598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1629"/>
            <end position="1674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1856"/>
            <end position="1936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1514"/>
            <end position="1523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1640"/>
            <end position="1657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1663"/>
            <end position="1672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1907"/>
            <end position="1919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1926"/>
            <end position="1936"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2001" mass="222508" checksum="2A3C3F006A15887D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBZ3</accession>
    <name>A0AAD8YBZ3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Derlin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_006074</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the derlin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBZ3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1540.10:FF:000016">
        <property type="entry name" value="Derlin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007599">
        <property type="entry name" value="DER1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11009">
        <property type="entry name" value="DER1-LIKE PROTEIN, DERLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04511">
        <property type="entry name" value="DER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1743453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="238" mass="27613" checksum="AF896792F0B194D0" modified="2024-05-29" version="1">MDFGGAAAIGGVDNGGFDFMSWYMDIPVISRLYFTGAFLTTAGCALDIISPFSLYFNFDLIFFQGQIWRLLTTYLFFGMFSIDFIFHMYFLVRYCRMLEEGDFRGRTANFVMMIMFGVIFMTAVAPFISVHFLGSSLTFMMVYVWGRRNEDIRMSFLGVFTFNAPYLPWVMLTFSMLLGNGVLMDAIGIIVGHTYYFLEYVYPAVAEIRGWRRKKILEPPRILHWICGTYHGQDLHRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCD8</accession>
    <name>A0AAD8YCD8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_006581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCD8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1742984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="167" mass="19610" checksum="84DA87976235BE04" modified="2024-05-29" version="1">MYLFQHDLPLVREINHTDILVTAEANDKMRLVGFKGDDPIQRPCGDDIVSESGIFYRRFKLWTDRNHFARIDHYKNDILPQVTSVFPEDNMHKPTRLNCTYFAPYYYEGGKGDPYYKHTDASERYGFKLFERVKRGEVAYSSLSKVNIMVMERMGVNMTELETYKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCI6</accession>
    <name>A0AAD8YCI6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peroxiredoxin-like 2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCI6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032801">
        <property type="entry name" value="PXL2A/B/C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13911">
        <property type="entry name" value="AhpC-TSA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042151028" description="Peroxiredoxin-like 2A" evidence="1">
        <location>
            <begin position="18"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="221" mass="24196" checksum="75F03C0DCF51BF1F" modified="2024-05-29" version="1">MRLVSLIATISVAVATAYVPPNMELPSSWTDVTQTQLTPLEFRSEAASALEGKDDVSEAACIDAASVIRQHSGSLGCIAFAVRRPGEDKPLDGFGLFGVVKEVGVDDPGLYDFYNDYFTYPLYKDESQTFYTALGTRKLAISTWNPIKMFRGMRNMSKRLSKKNISGNYKGEGIVQGGIIIFDAAGKARFAYREKTGSEVPVEDIIAVVKELRKEGKSQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD72</accession>
    <name>A0AAD8YD72_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S26</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_005752</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD72"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1740.20:FF:000007">
        <property type="entry name" value="40S ribosomal protein S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1740.20">
        <property type="entry name" value="Ribosomal protein S26e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000892">
        <property type="entry name" value="Ribosomal_eS26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038551">
        <property type="entry name" value="Ribosomal_eS26_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12538">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12538:SF0">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01283">
        <property type="entry name" value="Ribosomal_S26e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1743131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="106" mass="12559" checksum="96ABA16F4106033A" modified="2024-05-29" version="1">MTVKRRNHGRNKHGRGHVKRVRCASTGKAIPKDKAIKRFIVRNIVDASSLRDIKEASAYQEYQLPKLYLKMYYCVEAAVHQRIVRGRSRENRRIRTPPERKFVRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDI1</accession>
    <name>A0AAD8YDI1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_004781</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDI1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002673">
        <property type="entry name" value="Ribosomal_eL29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12884">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12884:SF0">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01779">
        <property type="entry name" value="Ribosomal_L29e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1744248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="57" mass="6685" checksum="4F20821FFB5B75EA" modified="2024-05-29" version="1">MVKQKNACQHNNTQKAHANGIKKKKRTKYVSTKGMDPKFLRNQKFCKKYNGSKRTQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDY4</accession>
    <name>A0AAD8YDY4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004955</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDY4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="124" mass="14774" checksum="0BE35F2130BE19EC" modified="2024-05-29" version="1">MTRRGVQFSISQTRITTYDNEIDRRSLIWYKPEDLQQFKEDRITDAIKITNDEYSENEEKICWWGLERLIVPSVRSKTMRAREQVKQVVLRKQDHACSDRQLMKASQWAATTAQKKATYYSSHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEB4</accession>
    <name>A0AAD8YEB4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004227</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEB4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="94" mass="10551" checksum="383F139973AA7CCC" modified="2024-05-29" version="1">MFSSALGKSVAFSGQKDDDANNNEVGQEEVGQEEETEAPAPPKEFQTLGMKLTFRKSLGTYALVCTRAKHSRDQHLLKPASLKRHRSRRKMGWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEK5</accession>
    <name>A0AAD8YEK5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">glutathione dehydrogenase (ascorbate)</fullName>
            <ecNumber evidence="1">1.8.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_004199</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-dehydroascorbate + 2 glutathione = glutathione disulfide + L-ascorbate</text>
            <dbReference type="Rhea" id="RHEA:24424"/>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58297"/>
            <dbReference type="ChEBI" id="CHEBI:58539"/>
            <dbReference type="EC" id="1.8.5.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GST superfamily. DHAR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.5.1" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEK5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045174">
        <property type="term" value="F:glutathione dehydrogenase (ascorbate) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033355">
        <property type="term" value="P:ascorbate glutathione cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00570">
        <property type="entry name" value="GST_N_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044627">
        <property type="entry name" value="DHAR1/2/3/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44420">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE DHAR2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44420:SF2">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE DHAR2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13410">
        <property type="entry name" value="GST_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0216">Detoxification</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042195193" description="glutathione dehydrogenase (ascorbate)" evidence="7">
        <location>
            <begin position="22"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="GST N-terminal" evidence="8">
        <location>
            <begin position="140"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="9">
        <location>
            <begin position="223"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1744908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="538" mass="60191" checksum="E765FC3A9C216A78" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEK6</accession>
    <name>A0AAD8YEK6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005622</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="308"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="355"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="501"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="375"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="397"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="413"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="438"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="453"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1282" mass="143082" checksum="E5D7C8F276C22029" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YF12</accession>
    <name>A0AAD8YF12_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YF12"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="611"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="851"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="466"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="676"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="686"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="720"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="740"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="858"/>
            <end position="875"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="882" mass="91873" checksum="C9CFEDB1CA52B385" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YF86</accession>
    <name>A0AAD8YF86_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003343</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YF86"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01763">
        <property type="entry name" value="Ubl_SUMO_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="105"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="476"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="577"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="702"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="487"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="577"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="708"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="746"/>
            <end position="759"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="828" mass="92353" checksum="E502BF31DCC6768B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFK3</accession>
    <name>A0AAD8YFK3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SPRY domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_003955</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFK3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035766">
        <property type="entry name" value="SPRYD7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20951">
        <property type="entry name" value="C13ORF1 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20951:SF2">
        <property type="entry name" value="SPRY DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="219" mass="24169" checksum="93D410E2CCC6424B" modified="2024-05-29" version="1">MGQCCCSPCKRFLPSSMIEFSGTAAAEAIMNEESLLENNIPQVHSINPEMSAPSIRVANDLGNEVKGYGLALTDVSVEQESCYWEWRVRTGGNPTVTVMVGVSNRRNSKFYEILASSSVPPEQHGTKFMCTASDLKDGDVIGIVVQQSELPMIQLYVNGEIEDGLQVTRFRGTVYPSIYLPQKGSNNDVSATFLYREEQYVHGPPGPQFHPLIAERSLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGV8</accession>
    <name>A0AAD8YGV8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGV8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1745309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="101" mass="10962" checksum="B4AE4EA88DC0BDE3" modified="2024-05-29" version="1">MAVDVPADHAHRLGMVLLASAPPVLEWLIRLSAHAHHVSNLTPPLANALHAQAHTLQIAHVQLALMSTLHFASALLALVLIPKTVDALYAVECREWKMTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGY3</accession>
    <name>A0AAD8YGY3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGY3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="344" mass="37740" checksum="F64FECD7FDFAAA2F" modified="2024-05-29" version="1">MRWMDSPKKTKACKTRFNTPARKTTVGTDSTDANNEVTGHKRAPKDSVSTLSASDRFPLTAQTIAIADNADTQEASGAITARFGRLLQECRDLTETCDNDSARDSMTSSYVESATKTTSSNMRSSTSDTDANEREKRLSSSQLKTAAAMAAANSSSLGRRSYTNPVTQKHEIDTSDGKHLHMSQLTVDPALHSSIMSADFRGSMMSMSEYKDLRASTLTGLLNNAEMKESQSSEEQSVEEFEDPKQSEEVDGYTETFQVPIDRPLGRREPRPEQPMARSVKSVVSELSLGIDVMYGDADEDAAFNRSGNLHEDLTAPFDPSRFLAELDPSSFGADRRSSETPRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YH37</accession>
    <name>A0AAD8YH37_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003028</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YH37"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041938472" evidence="1">
        <location>
            <begin position="20"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="120" mass="13263" checksum="C4C4950420EB5011" modified="2024-05-29" version="1">MKVRALILTVAAIANSAIAQDYQDYADGYEQDNLYQDYANKQQEQGGGGGGGLVKSIGAFGISYLIGAKVHSGRISKKMKTKHLKDQKALYTQYYNDVYRLEEQKAEQQAVIEQLQVALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YI20</accession>
    <name>A0AAD8YI20_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_003848</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YI20"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023779">
        <property type="entry name" value="Chromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051219">
        <property type="entry name" value="Heterochromatin_chromo-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22812">
        <property type="entry name" value="CHROMOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00598">
        <property type="entry name" value="CHROMO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="5">
        <location>
            <begin position="12"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="298"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="54"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="170"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="82"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="170"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1745924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="566" mass="63456" checksum="339A9204D576C0D6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIQ4</accession>
    <name>A0AAD8YIQ4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003845</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIQ4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="785"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="417"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1131" mass="128128" checksum="B27CA4111CBE68C5" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YK02</accession>
    <name>A0AAD8YK02_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002258</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YK02"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="10"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="91" mass="10198" checksum="87729EFD380A9962" modified="2024-05-29" version="1">MRSLLVADHNGDTPLHCACLAANYDVIELLLAQYPTAPVGERNVNDELPVQILLKHDEPENDGYMSSMFLLLRANPEMWMNDMNLVLALTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YK83</accession>
    <name>A0AAD8YK83_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YK83"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="790"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="491"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="522"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="565"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="581"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="612"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="632"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="711"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="729"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="741"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="811"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="843"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="874"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="893"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="906"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="954"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1000"/>
            <end position="1032"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1097" mass="118033" checksum="1E60C3C09683B9DE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKZ5</accession>
    <name>A0AAD8YKZ5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">N-acetyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_002379</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyltransferase family. ARD1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKZ5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031415">
        <property type="term" value="C:NatA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990189">
        <property type="term" value="F:protein N-terminal-serine acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990190">
        <property type="term" value="F:protein-N-terminal-glutamate acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045047">
        <property type="entry name" value="Ard1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23091">
        <property type="entry name" value="N-TERMINAL ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23091:SF4">
        <property type="entry name" value="N-TERMINAL AMINO-ACID N(ALPHA)-ACETYLTRANSFERASE NATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 7" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041944377" evidence="5">
        <location>
            <begin position="24"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="6">
        <location>
            <begin position="196"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="394"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="487"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="65"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="420"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1747035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="509" mass="57340" checksum="54C8EB805E687360" modified="2024-05-29" version="1">MHAMKHCWLHKLLMLYLLGCVGSNAFAIGGSKKGATHLAGNISRGGGGGGGRRAISRIIHLYNGSDNSSSSSSTALKQTSSYNEHPQHTPLIYKGGHICVRLARKSDVPQIQNCNLATLPENYNANFYVNHMRQWPDLALVAEHIPEGYDLQRDMESHGSAVEEEERITPLREYITKKRRRGDGSNQPPRKEIVGYILGKVEERPVNPIRQIFPQSRVPPLYDEEDTLLQYMDGANMNGARVFRQANQNQQQQQQQRRRTETLGHVTSIAVHSHARRLGIASSLLDQLHYHLGQCYNAKSVGLHVRISNQAAVKLYCERLGYDVADIIPFYYGDGEDAYFMKKDLLFVGDGDNDGYDDGYDDVVVEERRRLSQSSSFESRDEWINRDARSGGSFFDNQSSMRDSLSPEERAWINSGGGNNNNNNSSSQQRGSIGGHFKRSFQTFLNGGDPSPTPPPQGSRSWDNRPVWETGPEYLRLPRYTEIRKSMPGERIEDETARASMEYEQRVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLB2</accession>
    <name>A0AAD8YLB2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_000625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLB2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1748686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="194" mass="20903" checksum="9784ADA833DC40E6" modified="2024-05-29" version="1">MTMAQVAAKANPKLDRFRQLMAEKKLSNHSPSEIDSMQSSGEDALHSSSAGQSGAVEKISAGKSMQSIKENTHPNNNHAAMKQIMMKRGNIMTPKNESNQAVELAVSMDESDASPFAMLGNYLDESRLSQLGLGSIVSSLRSNDGIDNESIAITPAKWKRGNGQDAALGEWDASGILTFLESLLCLMNNKLTTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMH5</accession>
    <name>A0AAD8YMH5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Kinesin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_000158</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-13 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMH5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007019">
        <property type="term" value="P:microtubule depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01367">
        <property type="entry name" value="KISc_KIF2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000012">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47971:SF8">
        <property type="entry name" value="KINESIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47971">
        <property type="entry name" value="KINESIN-RELATED PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6 9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAM" evidence="12">
        <location>
            <begin position="5"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Kinesin motor" evidence="11">
        <location>
            <begin position="644"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="209"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="298"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1015"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1074"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="216"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="314"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="387"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="447"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="458"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="495"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="526"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1074"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="738"/>
            <end position="745"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00061030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1748219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1177" mass="128964" checksum="E6609C498183F54F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YNH6</accession>
    <name>A0AAD8YNH6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zinc finger PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_000524</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YNH6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger PHD-type" evidence="5">
        <location>
            <begin position="122"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="72"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="72"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1748585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="312" mass="34258" checksum="DA8B0FF0DD32D00A" modified="2024-05-29" version="1">MEQEDLQISIDSAAENDKEDCIPFHDIYSILSNYREKNGGLNIPRTDAAMSSLVPALNKIGFVQVPSAESKSVDDSVHDADKQSDADSIKQSSTAAAPIKRKVQDTPAVAAAANIATKIKGRCDICDQKDGFRGYNLQTCSVCCLAVHERCYGMTLTTTKNLNFACKACAAIGSKVEVNKPSILGKSSSTKETIRVQERPTECVLCNVHDGIHAMHPLFDTHGPKVASSKTGGSVYGCYGDDGRYEDDSDEEYADEENEVRFYAMATKEKGKETAWSRIITDSRKQSCVLFVEREITPVTRSEFHCNVLQMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPI7</accession>
    <name>A0AAD8YPI7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">L-rhamnonate dehydratase</fullName>
            <ecNumber evidence="5">4.2.1.90</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_001088</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.90" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPI7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050032">
        <property type="term" value="F:L-rhamnonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.120:FF:000005">
        <property type="entry name" value="Putative L-rhamnonate dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="entry name" value="Enolase-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="entry name" value="Enolase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013341">
        <property type="entry name" value="Mandelate_racemase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046945">
        <property type="entry name" value="RHMD-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF011968">
        <property type="entry name" value="PRK15440.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13794">
        <property type="entry name" value="ENOLASE SUPERFAMILY, MANDELATE RACEMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13794:SF58">
        <property type="entry name" value="MITOCHONDRIAL ENOLASE SUPERFAMILY MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02746">
        <property type="entry name" value="MR_MLE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00179">
        <property type="entry name" value="mandelate_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="Enolase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="Enolase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mandelate racemase/muconate lactonizing enzyme C-terminal" evidence="4">
        <location>
            <begin position="190"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1749149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="454" mass="50530" checksum="F869468A84C6BED0" modified="2024-05-29" version="1">MSLIFGPHPPVMPRKGETLIKEIRAYTFSSSSEEESGGGGADCHRQSSGHWIVDSDIANPMSVYAEYRDSRTSWGIGALGSVIVEVELDDENKTTGVGISIGGDAACFIVENHLSRFVEGQSPVNVELIYDQMWRSTMNYGRKGIAIQAISAIDLAIWDALGKLRGVPVFELLGGKTKDKIPCYATTSRPDLAQEMGFFGAKFPLPFGPASGEIGMQKNIEMVKKWREAVGPTFPLMIDCYMSLSVPYAIELARKCEPYNVKWIEETLPPDDYDGYSELKKAVKTTLITTGEHEYTRYGFKTLLEKKCVDVLQPDITWCGGMTEARRIVALSSAYDIPVIPHGSSIYSYHLQICFPSCPMAEFLVMSPKADAIVSFFGNLFLDEPLPKDGYVELPHDKPGFGVTLNREGLNMTRPYPRIIADKGASLVLRESYASKSKEQDMYYEIFNNCRFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3J9</accession>
    <name>A0AAD9D3J9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_016687</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000062">
        <property type="protein sequence ID" value="KAK1732626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3J9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1732626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="320" mass="36238" checksum="D944484A7A110555" modified="2024-05-29" version="1">MADQADAVEFFVYTGGRAPQHIINACISLSIDDIPDYAFNQCTRLVDVTFHDGVITIGKWAFPGCCSLQAIKLPGAKILRSNAFYNCTGLTEVAFGDKLEIIGLGAFYKCTSLRKLSIKSVKIIESGAFNGCEQLMDVDLPEEVERMEQYAFANCHAMRRIAMPLKTGMIANNVFNYCENLERIDLVGGIHRTISFLHLERWRDDMNDEINRINQILPHTPATGTIVGGKNEAIKRWIETAYRKMEHYKTEHYRLLRELAILLELALWKAKLEENDEDSPEKTVSAKLQIRQCSSKRSEVRITSGADIVIKNVLSFLRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3P0</accession>
    <name>A0AAD9D3P0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000065">
        <property type="protein sequence ID" value="KAK1732507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3P0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042116953" evidence="1">
        <location>
            <begin position="20"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="345" mass="38807" checksum="1E9278F8A6EBB1BF" modified="2024-05-29" version="1">MTLPRLVVLLALQIGLIKSFSPPISNIINNPQQQQQQQCTALQQSSKQSTPLSIEEDVNMIEIIELKGGIMKAISFAQNAKQMYDAILQAMPWFIRKLVQKNMNNAIAELMTVKVTENDMYDIIAKITPKSNLQDSLDVLDRYKTVTVVPQHHVKVADVHYSKEENIVATTMEEEEEELNAAAAEFFDEITFTQEENENLAASPTTQNLKEWTNTKMPAPAWLSSPHSLLSTASSSIDIDIDIIAGKKVHFKQNSKLMYDKILEGHTTLFFVRRVVKNNLDRAIISDFRKSCTSSNNTDDDGDDGVGVVIMDESDMYEVIHKASPRILLKFNMAILEEHQSTSSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4F1</accession>
    <name>A0AAD9D4F1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_016635</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000061">
        <property type="protein sequence ID" value="KAK1732658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4F1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36362">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36362:SF1">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1732658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="334" mass="37784" checksum="5B2FD4D38347B427" modified="2024-05-29" version="1">MMKQFAAAAALSSSGPQDQNEKMRQWDNWPAITYEEVQHALVTKGDSFFNQARELYYQKKQQPNNDNDKQQQTLMDESQTLFLAVKQINPTLVVESGVNAGVSTYIIRAASPTTKIFAIDPLAKPICGQGKRWVDPSDLTTNYWGGNFTDLLDLDWKGMIAKKEVDPGSTLVFLDDHLHTYNRIAGVRKFGLRHVVVEDNYKLGEGATPFDKKSTPKQMFHGEKWKKEGDWLFDNTVAYAEFPPLVPPIMAAAFKGKRKEAGGFMVAADDNKDIVHPMLRPDLNEDDMKLYAHVADTLGYDAALVDNESYMQFMNYNQICHLELKSDEKTTIDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4I0</accession>
    <name>A0AAD9D4I0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1800 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_016603</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000060">
        <property type="protein sequence ID" value="KAK1732704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4I0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014917">
        <property type="entry name" value="DUF1800"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43737">
        <property type="entry name" value="BLL7424 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43737:SF1">
        <property type="entry name" value="DUF1501 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08811">
        <property type="entry name" value="DUF1800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1732704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="713" mass="77326" checksum="99E3A044BDB9D4F6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4Z6</accession>
    <name>A0AAD9D4Z6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rhodanese-related sulfurtransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1734007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4Z6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020936">
        <property type="entry name" value="TrhO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040503">
        <property type="entry name" value="TRHO_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43268:SF3">
        <property type="entry name" value="RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43268">
        <property type="entry name" value="THIOSULFATE SULFURTRANSFERASE/RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17773">
        <property type="entry name" value="UPF0176_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="253"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="168"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="209"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="307"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="528" mass="60135" checksum="75C8633D999AFB09" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2024-10-02" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D503</accession>
    <name>A0AAD9D503_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000052">
        <property type="protein sequence ID" value="KAK1733214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="1">
        <location>
            <begin position="315"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1322" mass="149439" checksum="A4E1097692F174DA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5Q6</accession>
    <name>A0AAD9D5Q6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5Q6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="279" mass="30398" checksum="CABB07615084ACFB" modified="2024-05-29" version="1">MKQLSSPKRSNRGVHGSGPSKQLSASTLQTLETQVTCSTHQSRSRTPSPHQQRQARGMDPGGLIVIPRRKLPDATAAVTKRSAKAAAGDKEVKRNELPTTQQQQQRQETALVVASAVVTPPSILTITDDKESSSDKHEKNNNSVHQVKEVALTLYKDSNKSGTSKSTSSTAVGNKRSSSRPRASGTTSRNDTGIDGNKHHRSNKDDRGRKNKSKLSKSRSSRGNAKESKDAGEDRKNKKSGKTKEQTDKKEDKQPATKKNYPKGRRVSNSIQSAVVGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5R1</accession>
    <name>A0AAD9D5R1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SDR family oxidoreductase</fullName>
            <ecNumber evidence="3">1.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014675</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5R1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051122">
        <property type="entry name" value="SDR_DHRS6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43477">
        <property type="entry name" value="DIHYDROANTICAPSIN 7-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43477:SF1">
        <property type="entry name" value="DIHYDROANTICAPSIN 7-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="250" mass="26796" checksum="E54355C76238C57E" modified="2024-05-29" version="1">MGKAAAVQTVKNGGNVLLVSRSADKLQQAKEQIETACGGNIGRVKTRALDATDEAAVQAFANELSSEDWEFDALIVSAAGRAPHGPMTELPTADTRSMMETKFWTAYNAAKYINPKLREGGSITFVSGVLGRRPGINCCPLAVTNGALEGLTRSLALELGPRLRVNCLSPGFCDTERFDRMDTDRKAAMLANTADSLPLRRVGESSDMGEAIHYLATAKFVTGVVLDVDGGHSIRQYANSNSDPMRKQSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6L2</accession>
    <name>A0AAD9D6L2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase family hydrolase</fullName>
            <ecNumber evidence="1">3.1.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_014616</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6L2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.720">
        <property type="entry name" value="Haloacid dehalogenase-like hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011949">
        <property type="entry name" value="HAD-SF_hydro_IA_REG-2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044924">
        <property type="entry name" value="HAD-SF_hydro_IA_REG-2-like_cap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02252">
        <property type="entry name" value="DREG-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47105">
        <property type="entry name" value="OS02G0173600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47105:SF1">
        <property type="entry name" value="OS06G0665100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1734743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="304" mass="34476" checksum="DAFEEA75E408A910" modified="2024-05-29" version="1">MLRRTFVSLTSNSGKILHQNRQISSNERINNTKPKRIRAISCDVTGTLVSFLGRIEDHYGDAAHTCGVEISQEKKLLIRQSFNKAYKETSAAHPCFGNSCISSKEWWRRCVKRSFDLVGTSMDEPEEERVFQRVYSTFGSHAAYGVFDDAKPFLKWCMRHGIACGVLSNADERYGDSILPMLGLSDHMQFFTFSKNVGVEKPGKEIFDAAIQDAQPWLCLGNKRSDIKQLMPEEVLHIGNDYQKDYVGATSAGFHAVLLDRYDEKEVAKGWREGGAPVFKDLIDVVEWLGREQYELGSRDECKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7J8</accession>
    <name>A0AAD9D7J8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_011978</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7J8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042114495" evidence="3">
        <location>
            <begin position="20"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1737111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="189" mass="20261" checksum="63AFCBDE693BE1AC" modified="2024-05-29" version="1">MVAVLLAALSLLLLPGSHAFVHPVMQSSAVVTSTTSLSALPEFNPFLLADGLSAATRYGGSGFDNDVFADPAVTSALSTLRTFFIVLTAAAFGLTALAYITAAFIVPKAAEQLENDTKRLRPGLWEDYEAKLEDNQTMANRPDLLQELGNIMQPIITAEYERQAEEKFGPKAGAKKEDGGVIDVEVEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8Q2</accession>
    <name>A0AAD9D8Q2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010876</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8Q2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="77"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="145" mass="16031" checksum="D2E1428D980AB55F" modified="2024-05-29" version="1">MASESTAADGSNTAAITSPKNVPNFSHVPWPVRPRDGINYDFVATLYLIGSALALSFYLLETKILDPLLVENDVDATTTTGESDSTTGTEENGEEGSNAWKEFASGMQGMYFIFAPFVPCLLWSFVVRYFWLKETKKISLDKKDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAT3</accession>
    <name>A0AAD9DAT3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAT3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="1">
        <location>
            <begin position="124"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="236" mass="26710" checksum="66E3522F9D13E3ED" modified="2024-05-29" version="1">MNGIHLEAYVLNKQIQAKEAVVALHCESGWPLEFRQNFVPQISERIHGRLEGWSCYREYGTWKFHVSKGMMSVCEVRVPFGASPDETMERIERQLRRLMTLSADIDDVIANCLHDEAEQENTSSLILTKEQVRKNDGLEDRPLWAVIDGYVTDCTEFAKFHPGGLGKILATDEKQTGWTGEEFGFSLTRGSNAHFPKTGRVFQEGMRKFDKLQSQVEVNFGKDDGGAITILGKLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBF7</accession>
    <name>A0AAD9DBF7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">deoxyhypusine synthase</fullName>
            <ecNumber evidence="5">2.5.1.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_009588</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[eIF5A protein]-L-lysine + spermidine = [eIF5A protein]-deoxyhypusine + propane-1,3-diamine</text>
            <dbReference type="Rhea" id="RHEA:33299"/>
            <dbReference type="Rhea" id="RHEA-COMP:10143"/>
            <dbReference type="Rhea" id="RHEA-COMP:10144"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57484"/>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
            <dbReference type="ChEBI" id="CHEBI:82657"/>
            <dbReference type="EC" id="2.5.1.46"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; eIF5A hypusination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the deoxyhypusine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.46" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBF7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034038">
        <property type="term" value="F:deoxyhypusine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.910.10:FF:000001">
        <property type="entry name" value="Probable deoxyhypusine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.910.10">
        <property type="entry name" value="Deoxyhypusine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002773">
        <property type="entry name" value="Deoxyhypusine_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036982">
        <property type="entry name" value="Deoxyhypusine_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00321">
        <property type="entry name" value="dhys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11703">
        <property type="entry name" value="DEOXYHYPUSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11703:SF0">
        <property type="entry name" value="DEOXYHYPUSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01916">
        <property type="entry name" value="DS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0386">Hypusine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="51"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="492"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="500"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1739829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="533" mass="58736" checksum="31E5F83F9745DF1C" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBY9</accession>
    <name>A0AAD9DBY9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Trichome birefringence-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008494</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBY9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016413">
        <property type="term" value="F:O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029962">
        <property type="entry name" value="TBL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32285:SF48">
        <property type="entry name" value="PROTEIN TRICHOME BIREFRINGENCE-LIKE 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32285">
        <property type="entry name" value="PROTEIN TRICHOME BIREFRINGENCE-LIKE 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042043139" description="Trichome birefringence-like N-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="342" mass="39134" checksum="3F56DBB7E0938384" modified="2024-05-29" version="1">MRRRSIKIASLFLLGMGISEIIMQLKSAPQDATSTTREVQEDTEKRTLCTMEQLVQGKWTMGAEKDKPPYIPTPGERQQKTCHGFDPSARWQDWEWTPEDHSRCDFLNSDIDSNLFCSLARNKTIVIQGDSISFDHFLSLSHLLGVPVAPPRAVPKDPLRVSKICNGTSMLIGKKDFHLQQVGRIIKEFHPDVMILNRGAHYVSDEQLIQHLNSTVIPHIVNWQDECVLEKKDCHFVWRSTVPGHPHCTQFTKPAESVEEMEMMIATSPQYNWDKFKGQNELVMDLLSGSSLTAFNMFDGYPINILRPDLHGPAHNDCLHTCLPRDNIYSFITLHLLRLWSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DC76</accession>
    <name>A0AAD9DC76_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008538</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DC76"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042077544" evidence="1">
        <location>
            <begin position="20"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="144" mass="15591" checksum="0842D804AD02E8E6" modified="2024-05-29" version="1">MYMKSIALFVAIYGRTALAALPASCEVDNNCADACTPRNSEFEPPGVGQVWYSHCCTVSDTNTADPPVTESKKYCFLYYLTGYPNNQFFSTKPICSETGSGTLAWLRKGQCGTSSGSLSYQTSDSLVLVTLPYLAKAHQRAGVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCU0</accession>
    <name>A0AAD9DCU0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ethanolamine-phosphate cytidylyltransferase</fullName>
            <ecNumber evidence="10">2.7.7.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">CTP:phosphoethanolamine cytidylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_008267</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from ethanolamine: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.14" evidence="10"/>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCU0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004306">
        <property type="term" value="F:ethanolamine-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02174">
        <property type="entry name" value="CCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041723">
        <property type="entry name" value="CCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044608">
        <property type="entry name" value="Ect1/PCYT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45780">
        <property type="entry name" value="ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45780:SF2">
        <property type="entry name" value="ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cytidyltransferase-like" evidence="13">
        <location>
            <begin position="22"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1741015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="275" mass="30285" checksum="EBDFAA5CCF95858E" modified="2024-05-29" version="1">MASTPNRKKSSSQQPRQIRIFMDGAFDVMHYGHMNAFRLGRSLGTYLIVGVNSDESIKECKGPPLMNDEERMTMVKGCKFVDEVVPNCPYIMTSDYLDYIFETYDVDYVVHGDDPCIVDGKDVYASAKRLGRYRSIPRTEGVSTTEIVGRMLLMTKHHHMRHKQRGRGNSVGSLSGLSITGGGGGGAVGGGGMDEGNSSDDSDNEIHNDDEMDDELSVFTASQYNDGERIVIGNQSKFLTTSMMLRLFSAGVKPPGEGMRVIYVDGAFDMFIVVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCU8</accession>
    <name>A0AAD9DCU8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nuclear migration protein nudC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Nuclear distribution protein C homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_008297</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nudC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCU8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06467">
        <property type="entry name" value="p23_NUDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.790:FF:000001">
        <property type="entry name" value="Nuclear migration protein nudC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037898">
        <property type="entry name" value="NudC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025934">
        <property type="entry name" value="NudC_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356:SF3">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356">
        <property type="entry name" value="NUCLEAR MOVEMENT PROTEIN NUDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14050">
        <property type="entry name" value="Nudc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="8">
        <location>
            <begin position="196"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="108"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="124"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="165"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="176"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1741045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="361" mass="40186" checksum="0A3118DB374CE6FF" modified="2024-05-29" version="1">MSRPDYTNDDRFDGLFLQIAHQTQGIEPLLDTLFSFLRRKSDFFSPPGGGDIEKGSEAAIAKVNEVVKKHADIYLAGKRKEEEERLKKLRLKQKREAEAEAKKKKAAAAAAEKSKEGNDGVIEMGDDGFDISSDEPASTPAAAKAAAAAVSEPKADAPPAAPKTEQNENDGKDDDKQEEEEEEEDNSPPPIGNGGTIDGKYVWTQTLQELTINVPLPENTRGRDLNVIISKKHLKIGFAKTKQEFIVNDDLTKPIIVDDSLWTIEDGNRLVLTLQKSNQMEWWDAPCQTDEPKINIQKVQPENSNLSDLDGETRQTVEKMMFDQRQKALGLPTADEQKKLDILEKFKASHPEMDFSNAKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDN3</accession>
    <name>A0AAD9DDN3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LOG family protein</fullName>
            <ecNumber evidence="3">3.2.2.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007411</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDN3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016799">
        <property type="term" value="F:hydrolase activity, hydrolyzing N-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009691">
        <property type="term" value="P:cytokinin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.450:FF:000085">
        <property type="entry name" value="Cytokinin riboside 5'-monophosphate phosphoribohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005269">
        <property type="entry name" value="LOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00730">
        <property type="entry name" value="Rossman fold protein, TIGR00730 family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31223">
        <property type="entry name" value="LOG FAMILY PROTEIN YJL055W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31223:SF70">
        <property type="entry name" value="LOG FAMILY PROTEIN YJL055W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102405">
        <property type="entry name" value="MCP/YpsA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="319" mass="34732" checksum="BA20D4C49287C810" modified="2024-05-29" version="1">MASTSEEKKIDPMSTAAAESSSTMPLIEKAPTPLRVCCYGSSSSRTPKKYTDAAYNLGYHLAQRGHTCVNGAGNAGCMAAMNRGANDGDGAIVGVIHEAFVVDGSDWFEGAHSVFNTTKHRIITAKGNDLQERKKLLVQGADGLVVLPGGPGTWDELWEMACARHIGFHAMPIVCVNVDGYYDNFKSILVRAHEDELLYKQPEDILHFEESAEAAVKWIETYHALEATKQQPEQKKVIRRRTSMLKRMQSNLSGSTMTVWGRMSSFFGDDVCDDDDEEGEVASAETKSRRSATLSGITMFVAGVSVGLLAASKVGLRKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEL6</accession>
    <name>A0AAD9DEL6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glycosyltransferase 61 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_005945</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEL6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049625">
        <property type="entry name" value="Glyco_transf_61_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007657">
        <property type="entry name" value="Glycosyltransferase_61"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961:SF38">
        <property type="entry name" value="PROTEIN O-LINKED-MANNOSE BETA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Glycosyltransferase 61 catalytic" evidence="8">
        <location>
            <begin position="86"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1743324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="249" mass="28367" checksum="04472EAA38D4E1E0" modified="2024-05-29" version="1">MLKVFESAGISIKKPGGTNTTNQYREWIAAPNNIEQPSWPIPDRKDHPTVFKVDGPSYFINQHDVMSLQQHLLQQDYITRMAGSALPLQVLLFQRKGETREWVHAQETANKIKQAWGNWIEVKVLSTLNGNSLKEQALEFHRADIIVSPHGAQLTNLAFIRPCTVVLELFPNHYYLSYFQKYVLSAAGIHYEGYELGRSPLHDTMDTINNSELRGSAREKQMLASPQSILHALPRLILSCLSCQEDDQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEN8</accession>
    <name>A0AAD9DEN8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-hydroxyisobutyryl-CoA hydrolase</fullName>
            <ecNumber evidence="2">3.1.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_006515</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-methylpropanoate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20888"/>
            <dbReference type="ChEBI" id="CHEBI:11805"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57340"/>
            <dbReference type="EC" id="3.1.2.4"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.4" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEN8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003860">
        <property type="term" value="F:3-hydroxyisobutyryl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:L-valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045004">
        <property type="entry name" value="ECH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032259">
        <property type="entry name" value="HIBYL-CoA-H"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43176:SF3">
        <property type="entry name" value="3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43176">
        <property type="entry name" value="3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16113">
        <property type="entry name" value="ECH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl-CoA hydratase/isomerase" evidence="5">
        <location>
            <begin position="184"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1742918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="593" mass="64709" checksum="A34EE1E78D83ABAB" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEW3</accession>
    <name>A0AAD9DEW3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_003963</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEW3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990518">
        <property type="term" value="F:single-stranded 3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902969">
        <property type="term" value="P:mitotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17757">
        <property type="entry name" value="MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000003">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000115">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.870">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041024">
        <property type="entry name" value="Mcm6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF43">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18263">
        <property type="entry name" value="WHD_MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="14">
        <location>
            <begin position="534"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="418"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="856"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="418"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="876"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="916"/>
            <end position="926"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1744672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1031" mass="113479" checksum="205A05B094CC7972" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFA8</accession>
    <name>A0AAD9DFA8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_005641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFA8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="91" mass="10163" checksum="13F8DB0EFBF25C4E" modified="2024-05-29" version="1">MAVNPTEWLSSSMSACCKNSLGDTLNQCMGILAEGTEKWYVDYLALTCVKDCEGVSPCGGVAEAWDELFKDKKKCCEVKMPWTRKCLRNEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFL3</accession>
    <name>A0AAD9DFL3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003825</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFL3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042268868" evidence="2">
        <location>
            <begin position="23"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="211" mass="23016" checksum="1CAE9ABD732C44C5" modified="2024-05-29" version="1">MKLTTVAALLSTASSCCSMAAAFSTTSGAAASTVRHHFASQLMQQYGGEDQSQYYDNQQQQPEYYDEQQQNQHYYDGQQQQQQEEEEPSLLITDNMQQEMQRATANSDIGGLDYLALARQRAAARVESVNNQSTAADWQKLADEKAIESGGYVSEDEDWEASLGEEGSESDFNSLGMGAVSMVEGEGGVMMTEGGLVVDNMDGGDEPQLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFT1</accession>
    <name>A0AAD9DFT1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WRKY19-like zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFT1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056866">
        <property type="entry name" value="Znf_WRKY19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24906">
        <property type="entry name" value="Zf_WRKY19"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="2">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="312" mass="33487" checksum="09E598FF3590212B" modified="2024-05-29" version="1">MSSNQTKSTAGVWEGEEDELAVLIYKSSKTAKARAEAAAAAAATEEQMHAASASVGRRTSTRKRSASSSNDDDSASAEETQRKAVKRKEVDTATKIIGRDGRSRKKCSAAGCTNAAQNKGVCKTHGAKKKLCSSDGCTNQAISRGVCRRHGAKRKLCSSEGWRCVHEAWAILKRCSSEGCTNIAKKGGVCIRHGAKMKFCSSEGCTNYAINGGVCWRHGAKKKLCSNEGCTNKVQRGGLCMKHGAKVKKFVKGGVCMKHGATPKRCSSEWCTNYAKKGGVCQRHGVERKLCRAEGCTNQTQCGGVCKRHRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGA6</accession>
    <name>A0AAD9DGA6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005086</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGA6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042182752" evidence="1">
        <location>
            <begin position="24"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="60" mass="6986" checksum="EEFCC5057DABD0AF" modified="2024-05-29" version="1">MKCYSRAFMWNRLFLCKLLTLKSLKKVMIEIDDVDSMYKAGDAFRSSSSIVIVIKLEFAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGQ0</accession>
    <name>A0AAD9DGQ0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004294</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGQ0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd24142">
        <property type="entry name" value="ACL4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1745003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="321" mass="35159" checksum="727609CA2EB9857F" modified="2024-05-29" version="1">MQYLTAQNSESKAGLYLYLGQLSTGTEALTALRIGVSELQRTVSILDRLATSKDDEASGMDIDGELNSLNLKRFMVETKRQLCAAYCSIGELYLTDLCEEPDAENSCEAALKAAVEIDASAQSELGPSPPDALQTMANLRLSQSRVAEALDCIMKTYDRMKVGCEAMSGLVGLATDKEGVQEAKARELLELDAASTLPEYGFRLQTAKIMLECTSLVDDGNSNTKERCSESAIQVLGSLLSENDEVIEVWYLLGCAFMSCSPPNPDSARHYWENAVDMLTKAKEQMEHSGEDVACELEVIQSQLEEVTKKLDELGEEMETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGQ8</accession>
    <name>A0AAD9DGQ8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGQ8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="117" mass="13493" checksum="066DDBC51F01C5C1" modified="2024-05-29" version="1">MTWIVGLASNNLSVSANMHYDNEGQERSDNQERQEQRNNNNIAEQMLSTFFENLNYLEEQYGSNLVTVQDATDVYPILSQTNGGCPFDSRKFKMQQQEDKMPCYTPIVTIHDHITNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGS5</accession>
    <name>A0AAD9DGS5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">CobW C-terminal domain-containing protein</fullName>
            <ecNumber evidence="5">3.6.5.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_003244</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGS5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1220.10">
        <property type="entry name" value="CobW-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051927">
        <property type="entry name" value="Zn_Chap_cDPG_Synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43603">
        <property type="entry name" value="COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43603:SF1">
        <property type="entry name" value="ZINC-REGULATED GTPASE METALLOPROTEIN ACTIVATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00833">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90002">
        <property type="entry name" value="Hypothetical protein YjiA, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW C-terminal" evidence="4">
        <location>
            <begin position="108"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="18"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="67"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="87"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1746637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="300" mass="33645" checksum="7CAF357CF52A2346" modified="2024-05-29" version="1">MEVEFGKVDAKELLGKAFGSADDKNDSHDHSHNDHSSECNEAACADESHSHSHDHTTSDCSDPECTDTSHSHSHEHTSDCADPECTDTSHSHSHDHKTQTTSVDHLGITSFVYRASTPFNSQRLMALLNRWPIPIKDCLDFGLVMGLGEDDVDDAVDNKAFVGVLRSKGFCWMAPTKWSNSAGNDAWRHDTAMYWSHAGKHFGITSAGKWWGCLTKEQIKPYFANNMKEYDRIIAEDWVSEEWGDRRQELVFIGSKLNEAEIHEMEVYRAQVRNILEASFSSKKGGPSLFDVGGMDHIDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHJ6</accession>
    <name>A0AAD9DHJ6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DOMON domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_002707</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHJ6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09631">
        <property type="entry name" value="DOMON_DOH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045266">
        <property type="entry name" value="DOH_DOMON"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="SMART" id="SM00664">
        <property type="entry name" value="DoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50836">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042024523" description="DOMON domain-containing protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="DOMON" evidence="3">
        <location>
            <begin position="126"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1746100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="399" mass="42232" checksum="B331C0B35ADEF1A6" modified="2024-05-29" version="1">MIKVFMLVGIAAVLNNLPLQINAQRWPTYYPTYEPTFEETENDAQGDSGPGFPTYAPTPKQTTADLTTTDAPTKGDNGPDTLAPSAAVEMITPTKSPEIALATTPPTITAELSCPDSLPNTIEIDSISTLSYAIVPSNPPESNNGIFCGKLSSDNIGWIGLGISTDGLMSGSTAIIALPDDNSVLKYSLGNERSVNPMSEEQQTLRDTSILQLYGRTIMTFTKLLVEEDELPILTDGSVNFFIHARGFSNTLGYHGPSNRLSFQMDFGGVDIDADVTSMPVTASPTLSPSTLAPIQASKPWNDRPVITLAPTSISSKGTLSPTVASNNSTETDSPTPLSGSGDETILPIYVLPGESSTSSTNYSVSALEGFTSENGASSLVSIRGGFVLSLILSWGFIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJ40</accession>
    <name>A0AAD9DJ40_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Hydroxymethylglutaryl-CoA synthase</fullName>
            <shortName evidence="5">HMG-CoA synthase</shortName>
            <ecNumber evidence="5">2.3.3.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">3-hydroxy-3-methylglutaryl coenzyme A synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_001997</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>acetoacetyl-CoA + acetyl-CoA + H2O = (3S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10188"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43074"/>
            <dbReference type="ChEBI" id="CHEBI:57286"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Metabolic intermediate biosynthesis; (R)-mevalonate biosynthesis; (R)-mevalonate from acetyl-CoA: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the thiolase-like superfamily. HMG-CoA synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.10" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1748034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJ40"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004421">
        <property type="term" value="F:hydroxymethylglutaryl-CoA synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006084">
        <property type="term" value="P:acetyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010142">
        <property type="term" value="P:farnesyl diphosphate biosynthetic process, mevalonate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00827">
        <property type="entry name" value="init_cond_enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000008">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl coenzyme A synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013746">
        <property type="entry name" value="HMG_CoA_synt_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013528">
        <property type="entry name" value="HMG_CoA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010122">
        <property type="entry name" value="HMG_CoA_synthase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01833">
        <property type="entry name" value="HMG-CoA-S_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43323">
        <property type="entry name" value="3-HYDROXY-3-METHYLGLUTARYL COENZYME A SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43323:SF2">
        <property type="entry name" value="HYDROXYMETHYLGLUTARYL-COA SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08540">
        <property type="entry name" value="HMG_CoA_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01154">
        <property type="entry name" value="HMG_CoA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="5" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="5" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="2 5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hydroxymethylglutaryl-coenzyme A synthase N-terminal" evidence="6">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Hydroxymethylglutaryl-coenzyme A synthase C-terminal" evidence="7">
        <location>
            <begin position="167"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="3">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR610122-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR610122-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1748034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="570" mass="62315" checksum="28439569888A2307" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2020-12-02" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A6V0ZXN8</accession>
    <name>A0A6V0ZXN8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Prefoldin subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_001389</name>
        <name evidence="6" type="ORF">SMAR0320_LOCUS4105</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <dbReference type="EMBL" id="HBGZ01005887">
        <property type="protein sequence ID" value="CAD9583042.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A6V0ZXN8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002777">
        <property type="entry name" value="PFD_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016661">
        <property type="entry name" value="PFDN4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21100">
        <property type="entry name" value="PREFOLDIN SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21100:SF9">
        <property type="entry name" value="PREFOLDIN SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01920">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016477">
        <property type="entry name" value="Prefoldin_subunit_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="30"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR016477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CAD9583042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1747426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="133" mass="15074" checksum="A28417A4F3D7AEDF" modified="2020-12-02" version="1">MPEANGMILSKEEENDNEVRREDQDAINEFGRLNARLDEVKRQVDNLKKTLEKIDDASTELMMGDGDAVMLSLGGAMFEATEDEATEYCEAEVERQQKILDKLSEEEAGIVERQETLKKLLYGRFGKSINLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2M685</accession>
    <name>A0A7S2M685_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Thioredoxin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_000840</name>
        <name evidence="6" type="ORF">SMAR0320_LOCUS19906</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="HBGZ01027960">
        <property type="protein sequence ID" value="CAD9624736.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S2M685"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45663">
        <property type="entry name" value="GEO12009P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45663:SF11">
        <property type="entry name" value="GEO12009P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="82"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CAD9624736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1748901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="219" mass="24281" checksum="563483DE2ABB6E37" modified="2021-06-02" version="1">MKPTHNHQRQYACQRRRRYRQLTSAPVSLPLIIIGVILSSLIVRQGAEVNAFVHPSTISRLSFSHNKDLITDGANNYDISSTKRTPSLLSLSMVTKSGGRLISSIEQFDQEVLKDKDDGSENLPVLVLFSAPWCGPCRLTNPVVKEIMKQYQNKIEVVEISTDDLPEVASDAGVLSIPTIQLYYEGKLMDTIVGCVAKNVLARSVDKVLEDLGLLEETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSP3</accession>
    <name>A0AAD8XSP3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chitin-binding type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_016599</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000060">
        <property type="protein sequence ID" value="KAK1732700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSP3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042086343" description="Chitin-binding type-2 domain-containing protein" evidence="2">
        <location>
            <begin position="30"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="3">
        <location>
            <begin position="660"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="3">
        <location>
            <begin position="736"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="3">
        <location>
            <begin position="801"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="415"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="292"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="440"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1732700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="942" mass="100598" checksum="4A09310DD785C559" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XT92</accession>
    <name>A0AAD8XT92_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase</fullName>
            <ecNumber evidence="2">3.1.4.45</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.45" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000054">
        <property type="protein sequence ID" value="KAK1733102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XT92"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003944">
        <property type="term" value="F:N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033299">
        <property type="term" value="P:secretion of lysosomal enzymes"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018711">
        <property type="entry name" value="NAGPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40446">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40446:SF2">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09992">
        <property type="entry name" value="NAGPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphodiester glycosidase" evidence="1">
        <location>
            <begin position="458"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="571" mass="62339" checksum="1C2A875DA14A91A9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTZ3</accession>
    <name>A0AAD8XTZ3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zf-MYND and TPR domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_015862</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000049">
        <property type="protein sequence ID" value="KAK1733447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTZ3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="7">
        <location>
            <begin position="15"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="80"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="283"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1733447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="311" mass="34819" checksum="A0EAA937CC25F61E" modified="2024-05-29" version="1">MSGSSEESDEIMMCCALCGTAEVDDIKLKTCTACKSVRYCSVKCQREHRSQHKRACKKRAAELHDEILFKQPENSHKGDCPICCLPISLERTKSTLMSCCSKIICNGCVFSNDMRIFESSLEPTCPFCRHPDPESKDEGEKNITKRVNANDPVAMTHLGVLRYFEGDYDGAFRYQNLAANLGDSGGHFQLSCLYRKGHGVEKDRKKEVYHLEQAAIGGHPNARYNLGCQEEENGRMDRAMKHWIIAAALGHDGSLDALKDSFKDGLLSKEDFAAALRAHQAAIDATKSPQREEAEKLEREIKLDDIHRSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUJ3</accession>
    <name>A0AAD8XUJ3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000045">
        <property type="protein sequence ID" value="KAK1733762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUJ3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="179" mass="20157" checksum="6DA8C47902DE3994" modified="2024-05-29" version="1">MDGLSHYLQSSTQGAMIVPTQPMNKQKKLPQQQEDCVPPQYFSNSMSVLPADRYGSYYIIYHRDVSGECRDEMASHSFSTIGTRRDYGVERDGVFERTTPKQSVTFLETNNSMVETEPKNMMYDTNAGGSPRRSEQSSPTISMLDDEEYDNDSGFASHAAEACVACSIPVLHFIQFFMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUW7</accession>
    <name>A0AAD8XUW7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_015302</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1734044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUW7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1734044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="619" mass="69135" checksum="1C642F7CB060DE2F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVC4</accession>
    <name>A0AAD8XVC4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">subtilisin</fullName>
            <ecNumber evidence="6">3.4.21.62</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_014894</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides.</text>
            <dbReference type="EC" id="3.4.21.62"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.62" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVC4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04842">
        <property type="entry name" value="Peptidases_S8_Kp43_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051048">
        <property type="entry name" value="Peptidase_S8/S53_subtilisin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034058">
        <property type="entry name" value="TagA/B/C/D_pept_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399:SF4">
        <property type="entry name" value="CELL WALL-ASSOCIATED PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399">
        <property type="entry name" value="SUBTILISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="10">
        <location>
            <begin position="388"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="868"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="869"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="885"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="920"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="397"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="451"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1734387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="996" mass="105860" checksum="AC465B4E3CFB411E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXS1</accession>
    <name>A0AAD8XXS1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014041</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXS1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="154"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="76"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="305" mass="33952" checksum="FED4C2902FBE8922" modified="2024-05-29" version="1" fragment="single">MPPSYKKKESSPPAPPNNKQHIRFDSPEEKDADHQKKKDDGIIITSSKAAATVKTSSNDVSSSKSQKRKKKRKRATAATTTNPSDDNNTTNSEDKKIFNGLILALSTDNKVHQTTSNNSDNQSTKSCTTPTTTSTTSNNTNDDDDEQYETLKSLKTILKSTGATISPQVHKKVHYLICTQSAIDNLTQRIRQAIKRNVDIVSVDWVKKCISDNKRVDVTLYLWNEVAREIMVEKEREKKKKKSGGSDGNDADDGGYDSDIPQDDNGGWSEPVQLDCCCVCHENGDDNCPWCHDCNINLAKKQKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYM7</accession>
    <name>A0AAD8XYM7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013278</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYM7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="453" mass="43550" checksum="CE8AAC98FD7FBCA1" modified="2024-05-29" version="1">MAYHMSLMAAPTNRKSQMSCSILYLLLLAYVSFCTAFSNNYSFISLQLTTRCNNAIILCATKKQNNDNGNTSNESPFFFASVSNDNSTNTVGAVGTAAAAVGGAVVLSEASLTAATTTTATTTSTTAVLSGGRIAATSGGSIAAARSAAIGGTAASGIAATSTTTTISSTATSVTAATATSAASSASTTTAAVSGGRIAASGGSLAAARSAAIGGTAASGIAATSTTTTSSTATTAAAAGSTAAGRSVASGATALGTIASSRATTTIGGAGIVASEIGSSSLEGSGIGAVLESTSSSSAAILTDGSSSAITTALSGTEDLLVGDAATDAMLSAASDGVAGVGEVADTLLVAAGEAGAGALSILPSWLLSGGLAALASELAFGVFALFIVLQAGGNAAGDIVRSSVSKDASSSLMNEEVVKDKEVISEQEDTEDKEKSTESKAVEDGEIIEEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZ14</accession>
    <name>A0AAD8XZ14_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleotide-diphospho-sugar transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013116</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1735980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZ14"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="333" mass="37076" checksum="6FC84CE26C66459F" modified="2024-05-29" version="1">MVTFNRRGGTSSGGERQLFSIQKIFISLAVILVSLFLCALRLRSSLAEQYSVSSNPKDNSVSSNPKAIPKNKIVTSTRNSSGDSDKPIQVAYAISLIKCSDKQSSTSGLIDAATVLRHSVHQTSMRNPSSGSKYDYKMYAIVHKKAESCSHLLGDLGYHIIVKDSPVQTSEIRGDYLRKHVHKEWCCGADEFVKLFAYTIHDHPIVVHTDIDFMYVKPMDDLFDAMLLPHDSDEGKAARDKVELEYPDKQQSMPEDIQAYLTRDYHQVIPGRKAAFQAGFIVLKPNQKVFDEYLEIIREGNYVEGFSRENGWGGKGYGGVVGSMAMQGLPAII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZ37</accession>
    <name>A0AAD8XZ37_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-ketoacyl-CoA synthase</fullName>
            <ecNumber evidence="4">2.3.1.199</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_012591</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.199" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZ37"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00831">
        <property type="entry name" value="CHS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012392">
        <property type="entry name" value="3-ktacl-CoA_syn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012328">
        <property type="entry name" value="Chalcone/stilbene_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013601">
        <property type="entry name" value="FAE1_typ3_polyketide_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31561">
        <property type="entry name" value="3-KETOACYL-COA SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02797">
        <property type="entry name" value="Chal_sti_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08392">
        <property type="entry name" value="FAE1_CUT1_RppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="FAE" evidence="3">
        <location>
            <begin position="142"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Chalcone/stilbene synthase C-terminal" evidence="2">
        <location>
            <begin position="468"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1736569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="551" mass="61097" checksum="81F49EC88E046E19" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZI7</accession>
    <name>A0AAD8XZI7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heme-degrading protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZI7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.150">
        <property type="entry name" value="Haem-degrading domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052517">
        <property type="entry name" value="GlcG_carb_metab_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005624">
        <property type="entry name" value="PduO/GlcC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038084">
        <property type="entry name" value="PduO/GlcC-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34309">
        <property type="entry name" value="SLR1406 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34309:SF10">
        <property type="entry name" value="SLR1406 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03928">
        <property type="entry name" value="HbpS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143744">
        <property type="entry name" value="GlcG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042149623" evidence="1">
        <location>
            <begin position="18"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="246" mass="26181" checksum="C4F45E58A3B3EDA3" modified="2024-05-29" version="1">MKIIAGTISLLLPATNAFSPQLATAGRSSFRPIFSTALSSSSYLDNLSSVSTSSSFTATDEQATEILDSTFRRTVSSTANTPSSVPVMSKLSLNEADILANGVIDNVKRNEFPPIVVTVVDRQANILVQKRMDDVCHAAFPEFSYAKAFTCVTMGVSSREFRDKYTATNDAAKIGQMNSMMAISKMAAFPGGVLLRNGDNEIIGAIGVSGAAGDEDEYVALNSAWESGLPLETMPKEHSCTTVKSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZN8</accession>
    <name>A0AAD8XZN8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012704</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZN8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1736682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="132" mass="14689" checksum="EE4C196325D4AD65" modified="2024-05-29" version="1">MGGSGALLFSHLATESVVAFAPQVDLARDAHVSRDDMTLLVKEKFQTRLFENAEEAIKKGVTLFVHRGVESSDTQHTDQLMSRLASKCPLENERLKIIEHSDCNHHQIAVHLKQKGHLLEAISTCLMSNVVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZZ5</accession>
    <name>A0AAD8XZZ5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012996</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZZ5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041926358" evidence="1">
        <location>
            <begin position="19"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="559" mass="62073" checksum="EF51BF0C8C1E95B4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y087</accession>
    <name>A0AAD8Y087_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012664</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y087"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1736642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="333" mass="37300" checksum="7B71CAF0EC6A85F0" modified="2024-05-29" version="1">MSMQLQPKIKQHQECGVCGTFADGLQFIEVFDTPKYEDSEQVANEVPAKKDLCGHCVVGRDMPVCRQTEGWEFGEVTRYDSSKLSRPFLISFPDGSEEWVDISRRPSLDYLAFIRSTAQTQRAACAIEHLDWLDKFTFNGAESSPQMPTSLSTFSSSSSIGTFEPIAFGPSIFPLFNDDKLFDVENLAFVDEDVDMQDSFVESTQDSSEVSEITEPDDISSKALDKTRRSTTHEDHELIPRKGHQTEVAVSDMYCKRGAPTKGKYKFGKFKKVKRVTSCKRCCLLVPSAHTGVKICTVTGWCEACASIPSYVMGDDLRACLTQRMALDDFMLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0B5</accession>
    <name>A0AAD8Y0B5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcription factor E2F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_012096</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the E2F/DP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0B5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14660">
        <property type="entry name" value="E2F_DD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000008">
        <property type="entry name" value="E2F transcription factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015633">
        <property type="entry name" value="E2F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037241">
        <property type="entry name" value="E2F-DP_heterodim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032198">
        <property type="entry name" value="E2F_CC-MB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003316">
        <property type="entry name" value="E2F_WHTH_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12081">
        <property type="entry name" value="TRANSCRIPTION FACTOR E2F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12081:SF18">
        <property type="entry name" value="TRANSCRIPTION FACTOR E2F2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16421">
        <property type="entry name" value="E2F_CC-MB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02319">
        <property type="entry name" value="WHD_E2F_TDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01372">
        <property type="entry name" value="E2F_TDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144074">
        <property type="entry name" value="E2F-DP heterodimerization region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="E2F/DP family winged-helix DNA-binding" evidence="7">
        <location>
            <begin position="72"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="304"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="383"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="42"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="318"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="331"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="433"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1737229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="507" mass="55430" checksum="44C50D3B585DC00E" modified="2024-05-29" version="1">MPAVTPQRTRMSPSLPASKPSPQFTNPDKKSSPRASPSYRKSPSPTASAGSASSGSGNGSAFPACLMASNSRFDSSLGILTKKFVFLLKRAASHGFLENGVTIGPKAQGGDGTLDLNVAAEQLGVQKRRIYDITNVLEGIGLIEKRTKNHIAWVHDPRSGKDGPASQDNGENGLEEVSSNIICRGEEKMLMDEVDSLKSEEEKLDRHIAFMMNLVKSYSNSPRGTKVGNKKGNPWMYIRKDDLTSLTDLKDETVIAVRAPAGTTLDVPDPNDGMTPGSRKYQMYFKSPGEKVDVFLIQYGDDKNTSNCNGEKSHEFSKPSSKRTNPSAGAPERKRQRREDSEWPAAPSEIHQYLDCAASPSKMNQATSSNASYYSSWEKHASLSSSAKKLPRSPEQRDERSEENEASDYGFGSPPRNRSVTGSPRLHREIEATSSHSVVSTSTGHPSPPRGTILGDSPVKMTKCDSPTGSFDLMDDHFDDALMNPDRFFSHPFSPQNDDFLDFQPTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y0I9</accession>
    <name>A0AAD8Y0I9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SpoU family RNA methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_012814</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y0I9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051259">
        <property type="entry name" value="rRNA_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43191:SF7">
        <property type="entry name" value="OBP33PEP LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43191">
        <property type="entry name" value="RRNA METHYLTRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1736792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="315" mass="35323" checksum="B9CA6CC19670D936" modified="2024-05-29" version="1">MQDDNNHERQSPPRHFLLMHNPSKTTHLGTLLRCAAAFRAHQVLIVGHDKFNAQGSFGSHLYLDIVAFPSWECVVDYLKRGANDDGAHHDIITDAASAAHQTSTIDSSEDNRIPIVGISGAYGGDECIFSSDGVAVYEDADTGYATLSPRDAISSKEKKQKELPHKSYPIHTRPFSSDVCFLLSKDKRGLPVSHARICDSYVHVPQICFDADDSDTDAQLNTQEKIPRIIQSTLLETATIYSIVLHHFSAWANYNERNFAENQKFIKDTKSNMRRRLCRRYGENITTKAKDANNDLQTEGELIFEQSEGVFASDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y187</accession>
    <name>A0AAD8Y187_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y187"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="286"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="320" mass="33374" checksum="38835DBF56B7D478" modified="2024-05-29" version="1">MADTAAFFASKKKKGTKKKFKAFNANKIDANSVLSSTHVDAPEMSEGVSGLSLGGAKAGDNDDWDESQAVAWGSNAAATNSGADSKVSELLDMQALEVKRNEEDDVAERLRVEETKAQLARAKEGMAKEAERLAAEKAQKEAKAAERAAGGPATGGRWVPAHMRSSGGGVSVGGGGGGGLSSANEELFPDLASADKILADKERQEEEERKRSSSSQPIRAPSGWGSRMTGGSAATAAPTQRKPLNLAPAPVERKPLNLTPAPAAENSEAVDTKETVVEKTEDKPATETPAPAAAATPTPAPEKKKVLKKKKKKDLSSFKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1B2</accession>
    <name>A0AAD8Y1B2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sialate O-acetylesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_011556</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1B2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005181">
        <property type="entry name" value="SASA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03629">
        <property type="entry name" value="SASA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sialate O-acetylesterase" evidence="3">
        <location>
            <begin position="16"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="189"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1737784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="225" mass="25623" checksum="D7E1FEA26FDBA12D" modified="2024-05-29" version="1">MELGSSMNYTTRDFELHKVARGGSGLYEHWYPNHGMHWNLLRSAIEEQRGQQGDWKGFIWHQGSQAVWSAQQYGEDRSLTYYGNLTGLVSEVRELMFQNSITWRCKEEIPVVIVQVGFWPGYKDAANRTRDAQAKFCNQDPRAVLVKTDDLSRYYHYDAASFLISGNRIAQAYQEALGGVVECPDERVPSSSPSEKSMEPSMSLEPTVMRLETDLPSSINTNELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1M1</accession>
    <name>A0AAD8Y1M1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011519</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1M1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008914">
        <property type="term" value="F:leucyl-tRNA--protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.70">
        <property type="entry name" value="Leucyl/phenylalanyl-tRNA-protein transferase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004616">
        <property type="entry name" value="Leu/Phe-tRNA_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042203">
        <property type="entry name" value="Leu/Phe-tRNA_Trfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30098">
        <property type="entry name" value="LEUCYL/PHENYLALANYL-TRNA--PROTEIN TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30098:SF2">
        <property type="entry name" value="LEUCYL_PHENYLALANYL-TRNA--PROTEIN TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="104" mass="11686" checksum="50759313497310DD" modified="2024-05-29" version="1" fragment="single">MVWIGFGPRLSKSFVNCMMRLSQTLLNRSMYTTSQQTISLVVSWDTIGSINTSLTGFTFELYAGSIHLAVLGKLLTSSGFTHWDLGTGFEYKQRLGAVRIEREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1V3</accession>
    <name>A0AAD8Y1V3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011272</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1V3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="29" mass="3626" checksum="35F14D2CF69B77D8" modified="2024-05-29" version="1">MKMLLRNRPRSFWRRHWFTQATNPALLPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3V5</accession>
    <name>A0AAD8Y3V5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010753</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3V5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="52"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="188"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="393"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="419"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="282"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="10"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="122"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="206"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="458"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1738723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="652" mass="72205" checksum="6E9B86E33C334794" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5L6</accession>
    <name>A0AAD8Y5L6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sulfotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_009681</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5L6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008677">
        <property type="term" value="F:2-dehydropantoate 2-reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050838">
        <property type="entry name" value="Ketopantoate_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43765:SF2">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43765">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="54"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1739922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="401" mass="45814" checksum="DEFABD4832129F74" modified="2024-05-29" version="1">MNISTPPTLRSPSKATPSSHLCPTSTSKLLRIILSIGAVGLLLINQNYQGYDNLDNTSSLRDGAATVTSKDDDDANKDRQLRKPQQTAVEEEPQLDFAVVGFEKTGTTFLLEVFGNHPEITMPVKHSPDAAKICVRKEEGKETLKRWIQHQQQQEERQLVEEATSNSMKYGVKCSEMIRKPLGIENWADVSSANLIVGVRHPVEWFQSNYNYRVMLHHKDKLTSNIPSPHKLTDHHNCWHGVSTIAAQFDKYLQQLGKTPLDRNELSNLLDTLPTSDVRINHNPLKVFIYTIEQLEDTNTTRRTHFERDLQHFMGLTSPFDDFSSQAKSNVNKVTYPEYIDLCQPEFDSLRKSLVKEGKKSSEWIVNRFVMAEDVVVSDVEYFREKLRAWGEDPCSVVREQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y655</accession>
    <name>A0AAD8Y655_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009473</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y655"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF147">
        <property type="entry name" value="SEL1L ADAPTOR SUBUNIT OF ERAD E3 UBIQUITIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1739714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="217" mass="24408" checksum="45AA56032C9F10BB" modified="2024-05-29" version="1" fragment="single">MMMGCCSKMICNGCDYANKMREFAENLRHKCPFCRDPIPNSEAKAEAKFIQRVEANDPVAIREMGVRQYNDGDHESAFEYFTKAAGLGDVDAHFCLSSMYEKGIRVGKPHPLFARHDWGSMFGEGLPTLTSLMNEEGIDGSTKLTTLLGIGEKDEKKEMYHLEKAAICGHIEARYNLAICEKMHDRIYRAVKHWIIAANLGCDRSIQDLKLCYGNGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6N5</accession>
    <name>A0AAD8Y6N5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Drug/metabolite transporter (DMT) family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_008819</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6N5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23051:SF0">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23051">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35, MEMBER F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="313"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="348"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="98"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="110"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1740724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="380" mass="42552" checksum="BF6374029D790436" modified="2024-05-29" version="1">MWSSSYALGIFFLVIVSCLWTICSMVVQHLYHDMEFDSPFLIVYIGTSLFSVFLPIRLGYERFGHLLHKLQCWCCKDESSHHHDRKEIAVIPWGSYPSPVSESSDHQDENTTVSDAQELMQSPTDTDNYNGINRNDSKESIELTTSYLDESTSAEASALGILDDYSFNNEFCVQHYEPTRPMESRRSSNSDSSQNTGKKYSTYLLSHRDHISMASKVAPIWFLSNYFYAMSLEWTSIASSTVLASMGSIFAFGFATCSKFGDEKVTRGKIIGVLLCFSGGVATAYTDSGGDNSMRYLTGQFHVSDLDSSTRSLLGDLCGLVSAVGYGAYTVLLRHLCPKDEDRMSMQLLFGYIGLLNMVALLPVRYGCFYHQIMMSAGKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y736</accession>
    <name>A0AAD8Y736_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y736"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="173" mass="19956" checksum="6EEB4174BA26C8BA" modified="2024-05-29" version="1">MADNQQQHSSPRSRRSVRFNLEQNTTCKSKKHGAEYSQDAEAYWYTNEKVQSMLMSTVRNAAAYRQLIVRLRSIHGRANQHRFVAGLLGEHGVICIQGIEHLVSSVSIRRNLIRMRQQVIRAVIEEQARHEVHSDNKHVLIATKSMKHSNGWRDRARKIGMYHERDAGKSSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y762</accession>
    <name>A0AAD8Y762_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cell division protein FtsZ-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_008246</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FtsZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y762"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048285">
        <property type="term" value="P:organelle fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02201">
        <property type="entry name" value="FtsZ_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000023">
        <property type="entry name" value="Cell division protein FtsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00909">
        <property type="entry name" value="FtsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000158">
        <property type="entry name" value="Cell_div_FtsZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020805">
        <property type="entry name" value="Cell_div_FtsZ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024757">
        <property type="entry name" value="FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00065">
        <property type="entry name" value="ftsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="CELL DIVISION PROTEIN FTSZ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314:SF3">
        <property type="entry name" value="MITOCHONDRIAL DIVISION PROTEIN FSZA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12327">
        <property type="entry name" value="FtsZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00423">
        <property type="entry name" value="CELLDVISFTSZ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01134">
        <property type="entry name" value="FTSZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 13" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0717">Septation</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042105662" evidence="10">
        <location>
            <begin position="20"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="11">
        <location>
            <begin position="484"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="12">
        <location>
            <begin position="678"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="47"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="795"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="47"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="809"/>
            <end position="828"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1740994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="867" mass="93620" checksum="FF9A78EDF3894E15" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7D6</accession>
    <name>A0AAD8Y7D6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyl-lipid omega-3 desaturase</fullName>
            <ecNumber evidence="4">1.14.19.36</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_009294</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.36" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7D6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32100">
        <property type="entry name" value="OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041992454" evidence="2">
        <location>
            <begin position="23"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid desaturase" evidence="3">
        <location>
            <begin position="139"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1740344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="431" mass="48501" checksum="AA0767C847A00DDB" modified="2024-05-29" version="1">MKNNSIVTGALATTLLWTAADSFAPVYHSTQQQASATSLRSSILVDDVIRGTASNDPLSTVADMNDEDIAAMMRNDNPPLPGTIMKMLPKDTFQVDTATSLMYAGLDVAAVVGSMSFLYAVVQSDFYNGLPIAGQALTVAPLQILTGFAMWCTWCIGHDAGHGTVSKSTKFGKGINRIVGEITHSMICLTPFVPWALSHKKHHLNHNHLEKDYSHEWMIREEADDMPLFIKATYYIRMAYLPFLYFIYLFTGIPDGGHVLFYGRMWEGESMKDKLDGALSVAVSVATAGTLWHNMGTSDFAVVCMAPWTVMGFWLFMVTYLQHHSDDGKVYTDDTFTFEKGAFETVDRDYGEGVNALSHHMMDGHVIHHLFFTKVPHYRLHAATQALQKGMKERGQDHLYKQIDTPDFTQEIIKQYYNNWFYINEENIVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y879</accession>
    <name>A0AAD8Y879_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007197</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y879"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="263" mass="28743" checksum="18D89551729DEC2F" modified="2024-05-29" version="1">MNIEQFRARVAESAAAAHKAARHLSSLDEMAENDEYIQSPDLNVSTKTKKGMGHESSLSSFSNDANCSSEIPAVVEDLSTRFVDVISMAARSPSRSPLVASRTQSSTLELTAKKPGIQTTKSALIPSVAAVYEQNHSKKAPLQPKQKTEQSQLSSIQNSKAPKETLNEKHALILQQLDYDSDSDSSDGEQSIDSNSQPHNALHEELEYEVNEAIVSQESSSNLEKKDPNRFMTMTADLENEREALIANDTSISSASAHHIKTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8M1</accession>
    <name>A0AAD8Y8M1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_007706</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Endomembrane system</location>
            <topology evidence="10">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8M1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000383">
        <property type="entry name" value="Leucine-rich repeat receptor protein kinase EMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48052:SF8">
        <property type="entry name" value="LRR RECEPTOR-LIKE SERINE_THREONINE-PROTEIN KINASE FLS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48052">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1741228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="522" mass="56918" checksum="33A994B743D03759" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8Q5</accession>
    <name>A0AAD8Y8Q5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Helicase-associated domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_007301</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8Q5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.530">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005114">
        <property type="entry name" value="Helicase_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33418">
        <property type="entry name" value="HELICASE-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33418:SF1">
        <property type="entry name" value="HELICASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03457">
        <property type="entry name" value="HA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042052703" evidence="3">
        <location>
            <begin position="23"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase-associated" evidence="4">
        <location>
            <begin position="80"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase-associated" evidence="4">
        <location>
            <begin position="160"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="384"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="428"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="388"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1741728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="505" mass="59159" checksum="32BF4E73F5E8F1C6" modified="2024-05-29" version="1">MILPSRIFFYYVAFVCCGVAGAFKASSNHLTISTTYDARVKTSSSLLAYQQYKRRRKPVLSATSSEESTITASLRQKRNEELFQERLSQLHEFRAEHGHGSIPTPYHPNPSLGVWAANLRQQNVLRKQAERKSIEYEGYLTNERKRELINAGFDFTSLTERQFQTRIKELQEFKQRYGHTAVPEKYKDNMALGAWVSNLRSLYRRKLLTQNYDESDGSFEEEKSSEEEVEVYFGKPITEIRILEEIGFVWKNHDKRWFEMLEWAKTYAVYNYLQLSSESELKDSIESYYNKIVSELQDPRLTPTFRSQDEIMLLLLGEDCIRSVAEQSSQQLPPIQLNHSADIIGSVNVTESTLQLDYYISPSDHKHEPLRIWMINQRSNYNRRVQMKQSSSDDTSKSSLLQSTMTDQRQEALEQIHFPWSGRHRHRLEEVQYLEEKEAERIRELEKLARREAKEREEQEKVEMLKSSIVASIISGDKGGESDDDVEEEMDIMSLWDAEDDEDDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y964</accession>
    <name>A0AAD8Y964_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">23S rRNA (Adenine(2503)-C(2))-methyltransferase</fullName>
            <ecNumber evidence="10">2.1.1.192</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_007400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.192" evidence="10"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y964"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040072">
        <property type="entry name" value="Methyltransferase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30544">
        <property type="entry name" value="23S RRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30544:SF8">
        <property type="entry name" value="RADICAL SAM SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="514"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="9">
        <location>
            <begin position="165"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="71"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="478"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1741827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="543" mass="60413" checksum="CF9C43E37B9836F5" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9E4</accession>
    <name>A0AAD8Y9E4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007923</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9E4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="403"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="432"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="448"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1741445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="553" mass="58766" checksum="67639C7A05C0B823" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9V0</accession>
    <name>A0AAD8Y9V0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007446</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9V0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042297093" evidence="1">
        <location>
            <begin position="20"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="354" mass="38519" checksum="8C2ADBF5420E0626" modified="2024-05-29" version="1">MLFKAGLVAFAAADLNVLAFSPSSPSFTSTSSCSTQNKQLFSRVKTRFDGDCEQQLQTFDPLGFSDIADYGHEFSSSSPIVSSKAAVAAPILALSTIVIDPESSYAAATSSLSTGDFNPDNFRPVCGASDSFYRFLQGSTRAVVGDENFSEYGPLIAGGLLRIRLELCVVESFFNEAVGPFIKENGLNWILPIHESVETFLAGTIFALATTFILVGSTKLVQIIAFYGDLLFGGPCRLIGGFFFDRARGEPVTLDVSFFGFFKTRLVGPPVDFKEEEIKKVTGQTKLVDFDKVKPAEIPLIVLSGGVKLVGEASKVFREFIEALDLFVGRYLVLLASGYIILKFVHFKIFPDFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YA43</accession>
    <name>A0AAD8YA43_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Alpha 1,4-glycosyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006238</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YA43"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000030">
        <property type="term" value="F:mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051999">
        <property type="term" value="P:mannosyl-inositol phosphorylceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051706">
        <property type="entry name" value="Glycosyltransferase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007577">
        <property type="entry name" value="GlycoTrfase_DXD_sugar-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32385:SF15">
        <property type="entry name" value="INOSITOL PHOSPHOCERAMIDE MANNOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32385">
        <property type="entry name" value="MANNOSYL PHOSPHORYLINOSITOL CERAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04488">
        <property type="entry name" value="Gly_transf_sug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="576" mass="65155" checksum="8EBB3DA24F05FE9F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAH1</accession>
    <name>A0AAD8YAH1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_007612</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAH1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="entry name" value="Integrin alpha, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013519">
        <property type="entry name" value="Int_alpha_beta-p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36220:SF1">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX COMPONENT C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36220">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51470">
        <property type="entry name" value="FG_GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="repeat" description="FG-GAP" evidence="1">
        <location>
            <begin position="464"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="402"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="79"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="754"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1742039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="754" mass="80025" checksum="13612AF254F164C8" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YB77</accession>
    <name>A0AAD8YB77_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cGMP-dependent protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">QTG54_005865</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.12"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.12" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YB77"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030553">
        <property type="term" value="F:cGMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004692">
        <property type="term" value="F:cGMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000005">
        <property type="entry name" value="cAMP-dependent protein kinase catalytic subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002374">
        <property type="entry name" value="cGMP_dep_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF147">
        <property type="entry name" value="CGMP-DEPENDENT SERINE_THREONIN PROTEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000559">
        <property type="entry name" value="cGMP-dep_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00103">
        <property type="entry name" value="CAMPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0140">cGMP</keyword>
    <keyword evidence="9" id="KW-0142">cGMP-binding</keyword>
    <keyword evidence="7 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 13 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5 19" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="17">
        <location>
            <begin position="137"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="17">
        <location>
            <begin position="275"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="16">
        <location>
            <begin position="421"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="18">
        <location>
            <begin position="685"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="383"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="703"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="383"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="552"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="427"/>
            <end position="435"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="458"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000559-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000559-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK1743244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="739" mass="82402" checksum="37671ABBC62F9E51" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD80</accession>
    <name>A0AAD8YD80_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005614</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD80"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="166" mass="18794" checksum="52010B1F533AE154" modified="2024-05-29" version="1">MVDSTPLIPDGKEKKEGHRVLCCCDSRKAVIILNVLALALTIASLIIRLVDNQYFSAWTIILYVLNLFFYSIVAWGALQFGKSAVEWGIFWSIVDIIWASVYLARNSGWMVEGSSNRTATIVGYSIFYVFHVLIIYANWTYVSEVGKGIMSRETHSREKYSCCCNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDB0</accession>
    <name>A0AAD8YDB0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">2OG-Fe(II) oxygenase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006046</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDB0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035516">
        <property type="term" value="F:broad specificity oxidative DNA demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051747">
        <property type="term" value="F:cytosine C-5 DNA demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA alkylation repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032852">
        <property type="entry name" value="ALKBH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31573">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31573:SF1">
        <property type="entry name" value="DNA OXIDATIVE DEMETHYLASE ALKBH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="198"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="121"/>
            <end position="123"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="142"/>
            <end position="144"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR632852-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1743425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="303" mass="34715" checksum="C60C31844E82BA99" modified="2024-05-29" version="1">MMSKRQRTNSSSGARQQTTLLGLWKKPEEDKQSADDNLSSGRKRERDDDSDLSTPRPASKNNTVTSLLTGSKQQQWENISLHSNAPMMILRGGIGGKKKTSMRKSLVALPDWNENVTFHAFGRECTMRRRICQYSLQGKFSYSYSGLKNVQAPAFPSNLYEINNLETIEMDLSLSSEFIELVKQSAARSKQDEQRLDIFNYCLLNHYRNGQEYMSYHSDDEASLCQYSPIASISFGVTRSFDIRQKMTKGNKNETRSRIARIPLGDGDILLMFPPMQQYYEHALPVEKRVVGERINLTFRRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDD8</accession>
    <name>A0AAD8YDD8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004959</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDD8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="124" mass="14772" checksum="E7E5FE80337A19E4" modified="2024-05-29" version="1">MTRRGVQFSISQTRITTYDNEIDRRSLIWYKPEDLQKFKEDRITDAIKITNDEYSENEEKICWWGLERLIVPSVRSKTKLAREQVKQVVLRKQDHACSDRQLMKASQWAATTAQKRATYYCSHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YF23</accession>
    <name>A0AAD8YF23_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Opine dehydrogenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004798</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YF23"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051729">
        <property type="entry name" value="Opine/Lysopine_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38015">
        <property type="entry name" value="BLR6086 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38015:SF1">
        <property type="entry name" value="OPINE DEHYDROGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="703" mass="75452" checksum="5FD1E3431E111D7D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFM3</accession>
    <name>A0AAD8YFM3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein bL20c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_004284</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial ribosomal protein bL20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFM3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07026">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1900.20:FF:000001">
        <property type="entry name" value="50S ribosomal protein L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.20">
        <property type="entry name" value="Ribosomal protein L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00382">
        <property type="entry name" value="Ribosomal_bL20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005813">
        <property type="entry name" value="Ribosomal_bL20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049946">
        <property type="entry name" value="RIBOSOMAL_L20_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035566">
        <property type="entry name" value="Ribosomal_protein_bL20_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01032">
        <property type="entry name" value="rplT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10986">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00453">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00062">
        <property type="entry name" value="RIBOSOMALL20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74731">
        <property type="entry name" value="Ribosomal protein L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00937">
        <property type="entry name" value="RIBOSOMAL_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1744993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="212" mass="23813" checksum="3F265732896E2200" modified="2024-05-29" version="1">MLSQMSRRLVPVLGRAAKADTLPRLFSGLNITMRNNTSNLTAARSIGSMASLPSAAPIRSGTTMNSLMTRSVFANTNFATNNSIMLGTSSVTSQHQARGFASKKHKRVIKLSKGFRGRANRCFRVAIRRLEKSWQYAYRDRKVKKREFRKLWIQRLNAGVRQQGLSYSRFIQMEGKSGVKLDRKILSGLAMYEPFSFKAVVDVVKKMSAEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YG23</accession>
    <name>A0AAD8YG23_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">isopentenyl-diphosphate Delta-isomerase</fullName>
            <ecNumber evidence="3">5.3.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_003522</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from isopentenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IPP isomerase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.3.2" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YG23"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004452">
        <property type="term" value="F:isopentenyl-diphosphate delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009240">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02885">
        <property type="entry name" value="NUDIX_IPP_Isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011876">
        <property type="entry name" value="IsopentenylPP_isomerase_typ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02150">
        <property type="entry name" value="IPP_isom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10885">
        <property type="entry name" value="ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10885:SF0">
        <property type="entry name" value="ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="6">
        <location>
            <begin position="111"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1745598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="338" mass="38333" checksum="FBDDF6CD03046578" modified="2024-05-29" version="1">MTMMYKLNVRATVAIRCLLSRDTATASTRLRYAACAFHTQQPRRSSALQQHGWRQYSTTSNSLESWKGNTMSQSDFMERDTVLVLSDNDEVIGSASKKESHQFTPKNPRGILHRAFSVFLYDLSTQELLLQQRASTKITFPNVWTNTCCSHPLHGMDVNEVDAPEDVMDGTVKGVKAAAVRKLEHELGIPVGQLPMDSFKFLTRLHYWAADTVTHGEKSPWGENEVDYVLFVTVLNKDKITIEPHVDEVDDVCWVTKAKLFEMFADKDLLFSPWFRIIANRWMISSGEETGKGGWWDDLDRTMNTNEFCDYESIHRFDPQEEHLGGGGNAGPLFGVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YGM4</accession>
    <name>A0AAD8YGM4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcription initiation factor TFIID subunit 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_002836</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YGM4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046695">
        <property type="term" value="C:SLIK (SAGA-like) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08050">
        <property type="entry name" value="TAF6C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.770">
        <property type="entry name" value="TAF6, C-terminal HEAT repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037796">
        <property type="entry name" value="TAF6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011442">
        <property type="entry name" value="TAF6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046344">
        <property type="entry name" value="TAF6_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10221">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10221:SF9">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07571">
        <property type="entry name" value="TAF6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TAF6 C-terminal HEAT repeat" evidence="7">
        <location>
            <begin position="238"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="26"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="86"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="183"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1746229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="520" mass="58018" checksum="EC5A91388E9F5F42" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YH95</accession>
    <name>A0AAD8YH95_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleotide pyrophosphatase/phosphodiesterase family protein</fullName>
            <ecNumber evidence="2">3.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003314</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.-.-.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YH95"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10151:SF120">
        <property type="entry name" value="BIS(5'-ADENOSYL)-TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10151">
        <property type="entry name" value="ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="553" mass="61479" checksum="7EB7DFFB1EE79543" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHJ8</accession>
    <name>A0AAD8YHJ8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002038</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHJ8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="92" mass="10428" checksum="DEE9C15B4A7E49C9" modified="2024-05-29" version="1">MFDGGSSIPSAILSACEKLSQNILVMLLSRSNRVRLMTVICSLEEFLEWCIQKWIFEHYGRRSLIALGVNADNLWWILPELFPNGSIVIGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHL9</accession>
    <name>A0AAD8YHL9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_003075</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHL9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024766">
        <property type="entry name" value="Znf_RING_H2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45969">
        <property type="entry name" value="RING ZINC FINGER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12678">
        <property type="entry name" value="zf-rbx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="38"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="146"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="149"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1746468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="187" mass="21748" checksum="66DD1A1540F869C2" modified="2024-05-29" version="1">MEGQQEIPALQLTSRIASIFHDASNEDIEKASAEEEVCSVCLDGFDRHDVESDNNSNGSTVKKTRCGHLFHVNCLCEVVKRARLAGASKCPMCREPLDENGQLMLLSEEYLISVDREHIDSQEYNSDEEYDRWLDELHDEYANMMEQQRLQDEHDEELTRQEYEDVMEQQRLQDEHDEELSGKSMKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHS5</accession>
    <name>A0AAD8YHS5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHS5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="238" mass="26780" checksum="A7B7FF219DC3900B" modified="2024-05-29" version="1">MAKPTSRSSAKKPKGKHSKNKASAKSPPPSRNAPAADARASTARVEKSFVGDGSIITYLSQLIRFSSFVFDNYKGKLADDHLEKMTEADNKDKEEKNRSRTALRNYVVHAADAIKPLRDGQHHNSFLKIDGDDTLDYDTVVEYMTTKFNVVEVERSCAEKYMKALKLTDPITPEMVVDDGRVRLKVFQSMEQYNGIRSAIGWVYKIARVEMPFAQELGIYIKGITRHIAAAKHLLANW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIY2</accession>
    <name>A0AAD8YIY2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">40S ribosomal protein S4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_002942</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the eukaryotic ribosomal protein eS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIY2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06087">
        <property type="entry name" value="KOW_RPS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.740:FF:000001">
        <property type="entry name" value="40S ribosomal protein S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00485">
        <property type="entry name" value="Ribosomal_eS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000876">
        <property type="entry name" value="Ribosomal_eS4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032277">
        <property type="entry name" value="Ribosomal_eS4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013845">
        <property type="entry name" value="Ribosomal_eS4_central_region"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038237">
        <property type="entry name" value="Ribosomal_eS4_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041982">
        <property type="entry name" value="Ribosomal_eS4_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013843">
        <property type="entry name" value="Ribosomal_eS4_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018199">
        <property type="entry name" value="Ribosomal_eS4_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11581">
        <property type="entry name" value="30S/40S RIBOSOMAL PROTEIN S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11581:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN ES4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16121">
        <property type="entry name" value="40S_S4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00900">
        <property type="entry name" value="Ribosomal_S4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08071">
        <property type="entry name" value="RS4NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002116">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00528">
        <property type="entry name" value="RIBOSOMAL_S4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 11" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="RNA-binding S4" evidence="9">
        <location>
            <begin position="42"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="10">
        <location>
            <begin position="174"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="229"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="238"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1746335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="262" mass="29489" checksum="271CFDCF97FD2767" modified="2024-05-29" version="1">MARGPKKHLKRLNAPRHWNLGKMGGVWAPKPSAGPHKQRECLPVAIILRERLKYALTGKECQQICMERCVKIDGKVRTDMNYPAGFMDTVELEKSGDRFRLLYDTKGRFVLHRIQKEEAEYKLCRIQKVYVTAKKVPVAVTHDGRTLRYPDPDVKVNDTVKVSIATGKMSDIFSFEMGAMVMVTKGHNAGRVGQLVHLEKHDGSFSIVTVKDKKGNSFATRQSNVFVIGKGDHPQVTSPRDVVSRRLSSRSALRPRPVAISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJF2</accession>
    <name>A0AAD8YJF2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002772</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJF2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="193" mass="21445" checksum="DA47766EAB3ED9FC" modified="2024-05-29" version="1">MIFLLLNFQATIQLSDVTIQLSGGLLANVVPFIAARIPDGTLSNETQKILDDITVLAYDEVVNLSQSIFDNEDPKIYMALLEEGCSKFRNGGESCSGTSFYEPSSIRSEAQVITKCLPIRNKCRQCECLVNEVIYNQLIPGQVVEEKIGDAVSWTFAKLLAFIKSGKNDFASWFSAEGQFEMKSEVFAYLDSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YK05</accession>
    <name>A0AAD8YK05_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_003117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YK05"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041922222" evidence="1">
        <location>
            <begin position="20"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="149" mass="15917" checksum="43FFBACC98796F9D" modified="2024-05-29" version="1">MAPLRTLAALTLAATSVSAFAPASPAVSRPTTAVASAVFDDAVKDWAEEYPEFAKWGWGPSVQAEIWNGRHAMFGWVVMCACAYHQGHSDFPDADKMLDLKQWGTLATISDGLEKGKDTISNERAIILIANVHAFFVGIAATVAPPSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKA2</accession>
    <name>A0AAD8YKA2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_000100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKA2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033962">
        <property type="term" value="P:P-body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039900">
        <property type="entry name" value="Pat1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21551:SF0">
        <property type="entry name" value="PROTEIN ASSOCIATED WITH TOPO II RELATED-1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21551">
        <property type="entry name" value="TOPOISOMERASE II-ASSOCIATED PROTEIN PAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="177"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="327"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="213"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="254"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="349"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="380"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="397"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1748161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="802" mass="86547" checksum="C8C8F5D9662411CF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKG0</accession>
    <name>A0AAD8YKG0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_002090</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKG0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46972:SF1">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46972">
        <property type="entry name" value="MONOOXYGENASE ASQM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1746746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="310" mass="34258" checksum="91F67A460CC5A112" modified="2024-05-29" version="1" fragment="single">KSCLLQLRVHDVCCLNENLSNLRIDVTQNHATMTKRKNEDGLSTSIAIIGASYAGLTLANTLQQNSSSIKFTIFDSKTLPFTYVAGGDAFNVPSYSSLATKFSLKTSRQANNGLTRKDVTESLLDPVSQHLIVGTRIEKIEQRNNSFYLHTRQKLQSSDGASSTAAASSNNHRVHGPYRCVVGADGVRSKCRTSALNGTFLIGDARWVNDRWYDLGLRRIERGADIAILDGLELGELLLRAEGTENKDCHYSSQSFPLAARTKFCARQIQIARMKRIVSVLMVLVAMMVIKTLSMLQSLLLSILDRTKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKP8</accession>
    <name>A0AAD8YKP8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000117</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKP8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042093686" evidence="2">
        <location>
            <begin position="19"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="232" mass="25178" checksum="2E94208A0AEA0B51" modified="2024-05-29" version="1">MKLFLLATIALAFPGTSSVDAKGDSRPFGSKSSKTRKSQHGSEGCPPIHRTDDESAPLIINGTASPIDDEGRHPKNSEDGGLVLVDGTDDASGSEAVEEEEVDDALLIETFGDDDVSPSSTQGFDPAIAMFEWLKGCAEADLDKDTCLVTKTLDSLVNMDGHSQDDDSTFPSKRRVLQEEGCRPEMSEHDLRNIMNGSRADCMQVAIGYSDEVFEGMFMEFWKCNVPTSNLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKU6</accession>
    <name>A0AAD8YKU6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mediator of RNA polymerase II transcription subunit 10</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Mediator complex subunit 10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MED10</name>
        <name evidence="8" type="ORF">QTG54_000388</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the Mediator complex subunit 10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKU6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019145">
        <property type="entry name" value="Mediator_Med10"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09748">
        <property type="entry name" value="Med10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0010">Activator</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="153"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1748449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="200" mass="22310" checksum="F2BF7DAA3A682186" modified="2024-05-29" version="1" fragment="single">ASKLQTPHKSFTPSTNPNIAAGEYLLERFRILLSRLQTTTEILQNWPETQGDSAKIHNDTATELIASIRKIVTGLRTVERHVKALEKFRSSLDDKCPVPLDLLDLLDIGQPFGINPQCYARGLMKEAMLQLAGLERRKNALAMLGSAIEKGLNERSNTDDVEPAPESESATHKVVTVSKRKREEGDETDVVDMSKKMRTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YL58</accession>
    <name>A0AAD8YL58_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001333</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YL58"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041961377" evidence="1">
        <location>
            <begin position="20"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="269" mass="30311" checksum="A6C3A882F00BCFF9" modified="2024-05-29" version="1">MIWNGLWLTSLLFLTNLESLSDNETAIYAYPEIGCGVSQLSRSLLERMIRQQEDGKAHHVYEFVSTDVSLVCLQHNRDRDAAYIASLPDAATLSYTELNVVKELPACQMHKYDAILDKGTCDTFLFRSKRTQKGSASHAPLLKPLLNNVHRLLRSGCKAKYIIISPRSKLKSVRDFNGFVSVNRTKMSTDLLGDAVLVKGNAAHKPAHVFIYECTRNDSYQPDKDEPFADEGLTAINDEQSAKSVKRPSKNFVAMWTFRSRRDSMDSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLN4</accession>
    <name>A0AAD8YLN4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Eukaryotic translation initiation factor 2D-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001588</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLN4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001731">
        <property type="term" value="P:formation of translation preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.400.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039757">
        <property type="entry name" value="EIF2D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048248">
        <property type="entry name" value="PUA_eIF2d-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12217">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12217:SF4">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26292">
        <property type="entry name" value="PUA_elF2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Eukaryotic translation initiation factor 2D-like PUA RNA-binding" evidence="2">
        <location>
            <begin position="188"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="387" mass="42458" checksum="D1F2BB08F4BC3466" modified="2024-05-29" version="1">MFAKEGSSTIGGKKDAPLKKSDRRKLRDRSLDILFTTGGGGNESNDDNASEEWESRAEKLINDAIIAPKGGEVLSRKLKLASGQLATLFLRTPSPPADGVEHKHDKGSEDHQTYNDIIQSYPTTWPYHQTTQPILLEYEDGDRKLHLVPLIPLLAALPPPLPSSPLTKVVEESSITDAPSKSKQYKIPNISVHPQVSKYICRGADLMSAGIRTFPSPWALRQSKGLVTISIIGNPQPAAIGFVDRSLFREYCYPKNGGNRGEYDASAYVGVGTKGIGVTIVNCYGDDLWKLGLPTSTKQVEEGGSLNPLTGGAYDNGNYGNAGFVDGKYVYRILQEIEEDDSDEEENANEDEANENENNAVEETANEMKEMNLSDTKFSRQQKEVPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YM47</accession>
    <name>A0AAD8YM47_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NADPH oxidase</fullName>
            <ecNumber evidence="8">1.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_001987</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.3.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1748024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YM47"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000282">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF153">
        <property type="entry name" value="SUPEROXIDE-GENERATING NADPH OXIDASE HEAVY CHAIN SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="655"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="120"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="200"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="219"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="237"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1748024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1056" mass="117821" checksum="F558191A5B36F731" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YM65</accession>
    <name>A0AAD8YM65_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">26S proteasome regulatory subunit RPN1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_000487</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YM65"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042176">
        <property type="term" value="P:regulation of protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000026">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016643">
        <property type="entry name" value="26S_Psome_Rpn1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002015">
        <property type="entry name" value="Proteasome/cyclosome_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041433">
        <property type="entry name" value="RPN1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040892">
        <property type="entry name" value="RPN1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10943">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10943:SF1">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01851">
        <property type="entry name" value="PC_rep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18051">
        <property type="entry name" value="RPN1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17781">
        <property type="entry name" value="RPN1_RPN2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015965">
        <property type="entry name" value="26S_Psome_Rpn1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0647">Proteasome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="RPN1 N-terminal" evidence="5">
        <location>
            <begin position="72"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="26S proteasome non-ATPase regulatory subunit RPN1 C-terminal" evidence="6">
        <location>
            <begin position="878"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1748548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="940" mass="103227" checksum="236AC76711303299" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YNS4</accession>
    <name>A0AAD8YNS4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_000624</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YNS4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="117"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="250"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="36"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="393" mass="45066" checksum="873007F62BE82B8F" modified="2024-05-29" version="1">MMDDNSMEPQANPMNESVLISDDDASVESNEASDESTSISQGSRGRSSSKVKVYQSSTATSPSKASLMERNKTLVKEVRFADQTCVELSAKNKYYKEQYGQVKKNLVAANKDNSLLKETMKLRCRRILIRINELQKQCEEQQDQLKQARSECEMIGYDRDYWQSQCDGLHRQITQWNQSSDSLLDVFFNEDGSHNEDFINNLAFTPTKEKGGDASAITPADKALLEEELEEKCIAIAEFDELLEYKDAKIDELETMLEQQNVQIDNLLDEIDVMCNEENSEDESKQHASPSKEMRRRIVSLEERLDAAEEITVNEFDESNEKMNKELSNAYIEIADQKRFSDFQASTIERINEELSQSPRKMRKSDDTVRQRMAEFSIKIAELAAKVNDYHSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3D3</accession>
    <name>A0AAD9D3D3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Adenosine deaminase</fullName>
            <ecNumber evidence="8">3.5.4.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_016936</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; purine nucleoside salvage.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.4" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000068">
        <property type="protein sequence ID" value="KAK1732401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3D3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000034">
        <property type="term" value="F:adenine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006146">
        <property type="term" value="P:adenine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043103">
        <property type="term" value="P:hypoxanthine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43114">
        <property type="entry name" value="ADENINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43114:SF6">
        <property type="entry name" value="ADENINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Adenosine deaminase" evidence="7">
        <location>
            <begin position="3"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1732401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="228" mass="26310" checksum="3012B8F2270E6AC7" modified="2024-05-29" version="1">MAYLSRAKKDNVVYAELFFDPQCHKQRGVSFETMADGILAAVDDAYHELDIKCKLIPCFLRHLSEASAMDMWSEIFKYFQQHPEERDKIIGIGLDSDEQDNPPSKFHGVFWKIRHASKSVVGDLHIVTHAGEEGPSNFISQALDVLRSERKDHGVQCLSDDKLVQRLREKRIPLTVCPLSNVKLGVFDTLKQHNLKRMLDLGLKERQHSLRRSSLLWWIHYAELSRSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3F7</accession>
    <name>A0AAD9D3F7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Choline/carnitine O-acyltransferase</fullName>
            <ecNumber evidence="8">2.3.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_016885</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the carnitine/choline acetyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000066">
        <property type="protein sequence ID" value="KAK1732491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3F7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.70">
        <property type="entry name" value="Choline/Carnitine o-acyltransferase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000542">
        <property type="entry name" value="Carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039551">
        <property type="entry name" value="Cho/carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042231">
        <property type="entry name" value="Cho/carn_acyl_trans_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589:SF103">
        <property type="entry name" value="CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589">
        <property type="entry name" value="CARNITINE O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00755">
        <property type="entry name" value="Carn_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00440">
        <property type="entry name" value="ACYLTRANSF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Choline/carnitine acyltransferase" evidence="7">
        <location>
            <begin position="78"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="97"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600542-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1732491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="695" mass="76710" checksum="A8D8D86ACC248328" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3R3</accession>
    <name>A0AAD9D3R3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycosyl transferase CAP10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_016533</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000057">
        <property type="protein sequence ID" value="KAK1732821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3R3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF35">
        <property type="entry name" value="PROTEIN O-GLUCOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
        <property type="entry name" value="Glyco_transf_90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00672">
        <property type="entry name" value="CAP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="4">
        <location>
            <begin position="173"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1732821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="442" mass="50889" checksum="C800A25B9BBFFA31" modified="2024-05-29" version="1">MRMRQIRPARHRVKLSSIKNALMFLITFTFGYFSGMLPSYWLLTSEGPMLSSAKNSIGSIKAQFETNFKFPTVEERVKYYMGTWYNKNLTVPTSPESSLCKDLFVASSKSAIVPQRDSLYTFTDLQKRHQMPQMWQSVYLKDAANILSHVESHIDQQGEDEEKYIILKTGDGYSPDHNKPVVAKTRRHYEIENEARDGNGEEVDYDNKYIPIIWPIRLNYHFSGVEKLRSINQTDWDDKREEVVWRGACTGVEEGVHSSTGFPRLVFVEKHRFNKDKGIDVALKGRCGRISEEIQIKVDQSFYRGAIDMEKLLRYKYLLSLEGNDVATGLKWMLASNSVIFMPPPTAVSFTMESKLVPYVHYVPVKRDGSDLLSQLEWAKKNDDKCKWISEQATAYIENLWSSDQAAFDLIVIKHMMGKMYHEKFSKALAVCHSGCQSNKVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4D6</accession>
    <name>A0AAD9D4D6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015729</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000047">
        <property type="protein sequence ID" value="KAK1733556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4D6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="279" mass="29987" checksum="D6F3918D43F2DB49" modified="2024-05-29" version="1">MILVEEATSSDQDENNSNINSILNPAGPRLASQKRERSLVVLIITLIGLSIVIAATVGGVLGSRNNEKDNDGGGGGVVEKSEAPAISPMTSFAPSSSSLIPTSSPINSGVVPPTPTPSTNSSTTSPSFSPTLSICYNVDIIIIHDMYPGDTSWTIEQVEPPLPPNDTIVEFSPRNDTNQSRTVCLTRGLYNFTIFDDYPDGLCCEWGIGNYTLVYQGIEGGDEDEEEKVIASGGEFIASESTVFSIPYVDLNALRGRNEDEQESIVQERPLLYPKSRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4L9</accession>
    <name>A0AAD9D4L9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_016376</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4L9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051022">
        <property type="entry name" value="Notch_Cell-Fate_Det"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24049">
        <property type="entry name" value="CRUMBS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1 4" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="3"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="165"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="166"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="240"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="267"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1732838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="404" mass="44240" checksum="5AA1DEC6CC705FB3" modified="2024-05-29" version="1">MSSIPACQLNCLNGGYCNYISSDESTLIDTFARGGLIQTCICAPGYSGISCENRIEQCSTDLKCHNGVPCALDEKTGEYYCDCSYGDLISTFAGKMCREPATSYCGQGDIKNRSFCTNGGLCQSNIYRGVHFDESNDYSTHKGCACPPEFEGDHCEFLRTKPLDVSEQEVEAVESQEIEAEESQEIAAEESQEVEAEETTDQNDPEENKTSTEDSALAAPAPPTEEEPVAPLNHSKESNESNLPVTNENVQAEAPTHHDKTPPVQDQPLSNNDPPVQDQPPSKNAPPAPDNTLIDLESVSKEAIPIETITQSNKGSSVETNQLGGSIIVMISLTCAALIIGLLSYRRMRKRNHRKLENHFALGDNYKDETPIRVQVLSELEQPNELDEVLGWMQGALSMKMTMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5S5</accession>
    <name>A0AAD9D5S5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_014720</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5S5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039123">
        <property type="entry name" value="PPTC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320:SF1">
        <property type="entry name" value="PROTEIN PHOSPHATASE PTC7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="3">
        <location>
            <begin position="99"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="3">
        <location>
            <begin position="178"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="4">
        <location>
            <begin position="300"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU366020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1734847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="630" mass="68996" checksum="D9C458477B64322B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D646</accession>
    <name>A0AAD9D646_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Plastid lipid-associated protein/fibrillin conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013684</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D646"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041993765" description="Plastid lipid-associated protein/fibrillin conserved domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="418"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="794"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="522"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="535"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="552"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="575"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="806"/>
            <end position="816"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="816" mass="89834" checksum="6045826B863D5664" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D693</accession>
    <name>A0AAD9D693_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Trypsin-like serine protease</fullName>
            <ecNumber evidence="12">3.4.21.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_014920</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="12"/>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D693"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000054">
        <property type="entry name" value="Complement C1r subcomponent"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000005">
        <property type="entry name" value="Serine protease 37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF91">
        <property type="entry name" value="AT26814P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 12" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="8" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042033700" evidence="10">
        <location>
            <begin position="22"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="11">
        <location>
            <begin position="33"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="270"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="270"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="297"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="334"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="351"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1734413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="459" mass="47658" checksum="CF6ECDB3452EE62E" modified="2024-05-29" version="1">MLLSSFIKVFLYANLLALASANLFRGGVNNTRIIGGREMDEDSAPYSVSLMSSGSHFCGGSLITNRVILTAAHCLGGSISVLIGRHDFDDKDGELISASKQIPHPKYDEETSEYDMALIVLSRPVSGAVQAVTVNDDNSYPSVGTTARVMGWGNLKTNGFDLPDVPYMADVDVISNQQCEDLESGGNSYGKLKYPITSDMICTFSGGKDACQGDSGGPLVVRGNDASQDVLVGVVSWGVGCAYLPGVYGRPSQVYEWIKEEACAVSQDTTGSTLCGTESPTLSPTTAEPTASPSENPTSVPSSEPSAEPTASPSETPSLSPSSEPSAAPSLSVQPSEMPSSSPSLRPSGKPSASPSTWPSSSPTTSSQPSSEPTSMPSDVPSTSPSSNPSYSPSLSAAPTQSLAPTKPKLINTGVSLIISATELVDDEGNAIRNASSTFGSYAYVGSLMSFLISAWLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7K9</accession>
    <name>A0AAD9D7K9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012377</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7K9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="68" mass="7796" checksum="86B5DDDCF657B787" modified="2024-05-29" version="1">MKSTEVEHKNGKKKAKGKKKRKVDKPKQPKSKANKRTPKFPVTAGSRNTLWRCCKQQLSSSEEGKDKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7P2</accession>
    <name>A0AAD9D7P2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Trimethylguanosine synthase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Cap-specific guanine-N(2) methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_012113</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78479"/>
            <dbReference type="Rhea" id="RHEA-COMP:19087"/>
            <dbReference type="Rhea" id="RHEA-COMP:19089"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:167623"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:78480"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78507"/>
            <dbReference type="Rhea" id="RHEA-COMP:19088"/>
            <dbReference type="Rhea" id="RHEA-COMP:19090"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:167623"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="3">
            <dbReference type="Rhea" id="RHEA:78508"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78471"/>
            <dbReference type="Rhea" id="RHEA-COMP:19085"/>
            <dbReference type="Rhea" id="RHEA-COMP:19087"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:78472"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78475"/>
            <dbReference type="Rhea" id="RHEA-COMP:19086"/>
            <dbReference type="Rhea" id="RHEA-COMP:19088"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:78476"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7P2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071164">
        <property type="term" value="F:RNA cap trimethylguanosine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019012">
        <property type="entry name" value="RNA_cap_Gua-N2-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14741">
        <property type="entry name" value="S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14741:SF32">
        <property type="entry name" value="TRIMETHYLGUANOSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09445">
        <property type="entry name" value="Methyltransf_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="103"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="195"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="37"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="198"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00018517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1737246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="476" mass="52524" checksum="EE832D345FFFDAD0" modified="2024-05-29" version="1">MAAADAAVLDIDNQTSIAKDVTSSPSNKRKRSDCDDQTGNTKNNNNNNKRRKKKKGGGGKKQHHNKQRRNWIESCSESITRIPSNCAAPVTCVITRSEIEEEPLLPKQVGDDMTQSEDTKHTLDRDGDGADKIDCISNNEPAESNTSSSIEHPANNIATLSKSFVDTLSKEPIQPWKIATTLQVNGEEKKLFIPVQRHASTNGPTKWQQTQKKQGRHTQKGQNYSHLPDGDNGDGKKNPYPKKAVPDKFWAQRKRLFSRYDEGIQIGGEDDPEMWYSVTPESIGLHIANRMASMMNLDRKSTSGTGVGDTSNTQCNDSKKETVIIDAFCGCGGNSIAFARLNNNKDVAGSNTRMKLIAVDNNLSRLKMAANNASIYGISKEDIVLVHADAVEVVNAYEGGSRKKIQSDIPTNDRCCETYFGFAVGGVELLPDHVDALFLSPPWVEWIMTATKENLVLIQLMGSHWSQKCTTKRVTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8N4</accession>
    <name>A0AAD9D8N4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoglycerate mutase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_010980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8N4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051710">
        <property type="entry name" value="Phosphatase_SH3-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16469">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16469:SF27">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1738311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="294" mass="32462" checksum="45AD2C7A868F43DC" modified="2024-05-29" version="1">MAPSLLHQETTDGDVISRIFLVRHGDRFDYANPSWVDSAKKSGCLVTDPPLSALGHRQASETAAYLQKIIKENTPNNEDNEEGGSGGIHKILVSPYLRVIQTATPTAHAFGIPLSIENGLSEAHATATVLPTPHQRFAYFPMLDPNYNSLLNVKPTPGFYCPKTGFACEAFAGRYCQRMETFARCLERTHYGQTIVMFSHAASVALVAAFLRCSMTDLKFAPCGVYHLERVNDGPWKIVQSGHDNTSYVKENSPTTYPWGFSGKYFEENDGKYFGSSEGIDLDYFVGAPDNCNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8P9</accession>
    <name>A0AAD9D8P9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_012258</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8P9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="363"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1736813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="409" mass="46433" checksum="E44294ED13E9AD23" modified="2024-05-29" version="1">MANETEQQLREKIASQKISLARLPTLRSIIDETGLTSPETKARAQLFKELSDNEEQLELLLESERVAAVVRLQDELHPPQNSEGCPICLETIKHVNFMTIIRFYCCGGWICRQCYLAEKIDEMFHGRCALCRERIPDANNDHKEIGTMVLKHANKGRAWAQTHIGTCYLRGVNGYDLDKKKGLQFIKQAADQRDPEALFAIAFVCKGETLERDKSKYMYYLKDAADLGHTEAQQELALTYSTHEKEKRLHYTTLAASQGDAKACGMLGAYFIYAECGLTKSLVLAKHYCEKNLEDELSAYNFSLALLQLGLERYEGIMEIPGHSPIPTILFYERKVQEGEIHPIKGEATELISRLESQVKNHCANCRKEAGCSSSKRCVRCLGAWYCGKECQVQHWKAGHKIDCIKRMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D941</accession>
    <name>A0AAD9D941_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D941"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24121:SF21">
        <property type="entry name" value="ANKYRIN REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24121">
        <property type="entry name" value="NO MECHANORECEPTOR POTENTIAL C, ISOFORM D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1737385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="184" mass="20895" checksum="4883A0A4D0BB8079" modified="2024-05-29" version="1">MPRVHGIRVILSLWSELHEFCQSDSLSEEGLRQIIDRHECNDVSNYKFFREACCNERVTDGIIRCLLEYFPDAASLIDDTGWSPLCLACNRDMTPNIANIIRLLVDAAPDCVGSADNYGDFPLHFLCRKDSLDEMAAMQTLKLFLEKCPEAVRRANRNGDLPIHMAAKSKSPEFCRVNRSVSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9A2</accession>
    <name>A0AAD9D9A2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9A2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="77"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="167" mass="18247" checksum="8F3546363F5785EE" modified="2024-05-29" version="1">MRPLGMKTPHNNNAKNSSNNVKKSGQTTTQRRRRALGDISNKGGSAAKATGKNGSGGGLALNLINEQSGLSLIIASGSGIKSGKSSSLSSSSKPQQKKQSSSEYDGIFGVTTRWSNTNLDHDRPSPFAQLPKEEFELSNNVAEEIRQHRLKERVRKEEAEEKRWRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9Z7</accession>
    <name>A0AAD9D9Z7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">formate C-acetyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">QTG54_009361</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>formate + acetyl-CoA = pyruvate + CoA</text>
            <dbReference type="Rhea" id="RHEA:11844"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.54"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the organic radical-activating enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.54" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9Z7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008861">
        <property type="term" value="F:formate C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050244">
        <property type="entry name" value="Auton_GlycylRad_Cofactor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019777">
        <property type="entry name" value="Form_AcTrfase_GR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001150">
        <property type="entry name" value="Gly_radical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004184">
        <property type="entry name" value="PFL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001989">
        <property type="entry name" value="Radical_activat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30191">
        <property type="entry name" value="FORMATE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30191:SF0">
        <property type="entry name" value="FORMATE ACETYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01228">
        <property type="entry name" value="Gly_radical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02901">
        <property type="entry name" value="PFL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01066">
        <property type="entry name" value="organic_radical-activating_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51998">
        <property type="entry name" value="PFL-like glycyl radical enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00850">
        <property type="entry name" value="GLY_RADICAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51149">
        <property type="entry name" value="GLY_RADICAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51554">
        <property type="entry name" value="PFL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01087">
        <property type="entry name" value="RADICAL_ACTIVATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="15 21" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="21" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 17" id="KW-0556">Organic radical</keyword>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="8 21" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PFL" evidence="19">
        <location>
            <begin position="115"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="domain" description="Glycine radical" evidence="18">
        <location>
            <begin position="721"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="20">
        <location>
            <begin position="897"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="modified residue" description="Glycine radical" evidence="17">
        <location>
            <position position="819"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAK1739602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1139" mass="126437" checksum="C3824BBA9807CA39" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DA29</accession>
    <name>A0AAD9DA29_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">NEDD8-activating enzyme E1 catalytic subunit</fullName>
            <ecNumber evidence="8 11">6.2.1.64</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_011133</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>ATP + [NEDD8 protein] + [E1 NEDD8-activating enzyme]-L-cysteine = AMP + diphosphate + [E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine.</text>
            <dbReference type="EC" id="6.2.1.64"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Protein modification; protein neddylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.64" evidence="8 11"/>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DA29"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019781">
        <property type="term" value="F:NEDD8 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045116">
        <property type="term" value="P:protein neddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01488">
        <property type="entry name" value="Uba3_RUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.520:FF:000001">
        <property type="entry name" value="NEDD8-activating enzyme E1 catalytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.20:FF:000003">
        <property type="entry name" value="Ubiquitin-activating enzyme E1 C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.520">
        <property type="entry name" value="Ubiquitin activating enzymes (Uba3). Chain: B, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.20">
        <property type="entry name" value="Ubiquitin-like 2 activating enzyme e1b. Chain: B, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014929">
        <property type="entry name" value="E2-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023318">
        <property type="entry name" value="Ub_act_enz_dom_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030468">
        <property type="entry name" value="Uba3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033127">
        <property type="entry name" value="UBQ-activ_enz_E1_Cys_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF6">
        <property type="entry name" value="NEDD8-ACTIVATING ENZYME E1 CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08825">
        <property type="entry name" value="E2_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01181">
        <property type="entry name" value="E2_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00865">
        <property type="entry name" value="UBIQUITIN_ACTIVAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="E2 binding" evidence="13">
        <location>
            <begin position="379"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="42"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="10">
        <location>
            <position position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1738464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="462" mass="50770" checksum="A0DB99C3B0B75278" modified="2024-05-29" version="1">MTSQKRSALEMTNSSPTNALPIPQDTTSRPPLSGRQRGSLKTLLTRSSPFANETGSLPIGEFDTSNGGSQHATSTAKILVVGAGGLGCEILKDLAMSCVVRDIVVIDLDTIDVTNLNRQFLFRSKDVGHSKAEVAAKFINERCPWMNVEFYHGKIQDKDAEFYRQFKVVISGLDNVEARRWLNGMINNLVEFDEDGDPNPETIIPLVDGGTEGFSGQSRLILPRITSCFECSLDAFAPTAAVPLCTIAETPRIPEHCIAYAYVLQWAKEFPDRKLDTDSPADMKWVYEKALERANQFGIGGVTYMLTMGVVKNIIPAVASTNAIVSAVCVNEAMKVLSFCSQSLNTYMMYMGSEGIHSHTFVYEQKSTCPVCTTHVHRMALSPSTTLNALLQQLCEGEFRLKSPSVTSSSKTLYMRKPAALEKATKGNLDKPLNELINSGEELTITDPVFHDTSLQLIVTFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAK5</accession>
    <name>A0AAD9DAK5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Histone H3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_010733</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the histone H3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAK5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22911">
        <property type="entry name" value="HFD_H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000078">
        <property type="entry name" value="Histone H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000044">
        <property type="entry name" value="Histone H3.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11426">
        <property type="entry name" value="HISTONE H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00622">
        <property type="entry name" value="HISTONEH3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00322">
        <property type="entry name" value="HISTONE_H3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00959">
        <property type="entry name" value="HISTONE_H3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="10">
        <location>
            <begin position="44"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1738703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="136" mass="15300" checksum="EC4C4557B3BCB519" modified="2024-05-29" version="1">MARTKQTARKSTGGKAPRKQLATKAARKSAPTAGGVKKPHRYRPGTVALREIRKYQKSTDLLIRKAPFQRLVREIAQDFKTDLRFQSTAVLALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DB39</accession>
    <name>A0AAD9DB39_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008233</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DB39"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13578">
        <property type="entry name" value="Methyltransf_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="561" mass="62896" checksum="B8909DA70D028AF3" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBJ8</accession>
    <name>A0AAD9DBJ8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009529</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBJ8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="202" mass="22719" checksum="2B3BD79DEB4ACA7D" modified="2024-05-29" version="1">MNKAYAISRLGSVVCRSRLNRSVLSCATFSSSTSDDDITVTKTQQPKRRTRRRQLSNDDNESVPSLADFMHRAKVRQQYRHFIRLAHFVDGSNTSAAAGNEGEAATGECRAALEEVRLSFQLGVKKGTDNLSKTMAFQDGERRLRQLEAMVGYSRKSTTSKDEQASAEESYEADSWINIKDEEDKRGRVGVAWPWESDNESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBP1</accession>
    <name>A0AAD9DBP1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009034</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBP1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="162"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="484" mass="53796" checksum="FF64ADB671995B09" modified="2024-05-29" version="1">MAKANATQFNLNETEAAEVIKETVAVAEPTEKDEPGGLEVIVYAGTGAGVMFCFMAAGLSLIYIKKRRRRTGKRKREVDEDAVTGDSKSKKSAPKRELWTKLKRGSATTDVESDEIPNTTSGALPDTSHDNSERNASVPDIETGVKTITPNIPDTPEENVGSSLTSLESSEISFEAVIKKDRPFKPSSKSSRKLIDESKNSGSGKSRRNLNDEGKLYSGQSRRNLDDKRKSRRNLNDEGKLSSGRSTRNLGDKRKSRRNLNDERKLSSGRSTRNLGDKRKSRRNLNDEGKLSSGQSTRNLGDERKLPSGKSRRRLTADETSARPIVDRPPKSFRKSTGMSGTPSVESGSSHSSRRRDSGSSHSSRRGGAGDSKRDGKLSSEKSRRINDQDRDEIRRERIEKRRERRSKNSFPEESNALQSSDRSGRSKLEDSDRPEALSRSVGSAAWSMASDRNKGGERRRSRKNSPKSPKRDLQRSKSRRDVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DC97</accession>
    <name>A0AAD9DC97_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DNA ligase</fullName>
            <ecNumber evidence="9">6.5.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_007680</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.1" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DC97"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07896">
        <property type="entry name" value="Adenylation_kDNA_ligase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08041">
        <property type="entry name" value="OBF_kDNA_ligase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029319">
        <property type="entry name" value="DNA_ligase_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050326">
        <property type="entry name" value="NAD_dep_DNA_ligaseB"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006592">
        <property type="entry name" value="PRK09125.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47810">
        <property type="entry name" value="DNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47810:SF1">
        <property type="entry name" value="DNA LIGASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14743">
        <property type="entry name" value="DNA_ligase_OB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-dependent DNA ligase family profile" evidence="7">
        <location>
            <begin position="198"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="DNA ligase OB-like" evidence="8">
        <location>
            <begin position="369"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="105"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="153"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1742107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="440" mass="48422" checksum="3183F06D55B069D1" modified="2024-05-29" version="1">MPTAISFFPVGSSVTLQNLVNAAHYNGLCGTVQSGADPQSSRQEVAIDVDGEKKVLAIKPANLRPFNDDVLSMSIKELLSELADYNISTDTMKDKSSLQEAVIAARKDGWRRPTKRKSVLKTPPPPPAAAASAAASSAASDECDIGKFSSGYNSGKKRTASDASDSKPSKKAKVNASDTHQGSLPELALAKKWDESMNVKGYYLSEKLDGMRCLWDGLGNLYSRNHNIIHAPSYFTQALPTGIALDGELFVGRGEFQECMSIVKQTKPDEQDWRRVTFFCFDAPSIAGGFDTRLQAVKEALANTDTSIAIARVGKDHLLEEFARVRNQNGEGIVLRKVNVPYRGKRTSDLLKYKEFMDAEATVVGYQDGKGKHSGRMGALICQMLDTVRAEFKVRSGFSDDEREWENTPSIGSTITYRYYELTNDGKPRHPVFVRVRPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DC98</accession>
    <name>A0AAD9DC98_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dynein light chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_008555</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DC98"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21459">
        <property type="entry name" value="DLC-like_TCTEX1D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.40">
        <property type="entry name" value="Tctex-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005334">
        <property type="entry name" value="Tctex-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038586">
        <property type="entry name" value="Tctex-1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21255:SF7">
        <property type="entry name" value="DYNEIN LIGHT CHAIN TCTEX-TYPE PROTEIN 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21255">
        <property type="entry name" value="T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03645">
        <property type="entry name" value="Tctex-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1740460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="129" mass="14703" checksum="261E86629D8F087C" modified="2024-05-29" version="1">MTVDIKTIVEPTFRTTPEDACKLYPTKAKLIADEILCEKLENKSADDVEFEFEELSKSIADEVKEKIKASMHIPRYKVLVQATIGTMKDQGVKITSRCLWDTSTDNYATASFQNEFIFASVLVFFLYTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCC1</accession>
    <name>A0AAD9DCC1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Immediate early response 3-interacting protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_008630</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the YOS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCC1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013880">
        <property type="entry name" value="Yos1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15858">
        <property type="entry name" value="IMMEDIATE EARLY RESPONSE 3-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15858:SF0">
        <property type="entry name" value="IMMEDIATE EARLY RESPONSE 3-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08571">
        <property type="entry name" value="Yos1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1740535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="83" mass="9235" checksum="D0E1F5530D6C6034" modified="2024-05-29" version="1">MGFSLWNIFKAGLLFTNAIMILHRKRFLSKYGLDDVNNMGCNPSERPFQVQAIGLLQAVHYLKIPVIMANVVAIVFELLLGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DD08</accession>
    <name>A0AAD9DD08_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_007957</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DD08"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="215"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1741479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="264" mass="29668" checksum="E54E6E43496CFA83" modified="2024-05-29" version="1">MTSLKRANGKATRAAKAKAKVAVAAQNQPLQGRQMQTIDADRSDSAAKCDHGLVPSHYHWKSHREILDTYMNQCKVFLQAFVDEFDGAGGDFLAAYHATKEKYVGVWKDFGKMSFVVSFLLACGTSKVLEGNTRIARKYAALSSYFEMYVEVDLLNTRAFPSWAKINELYSADMHTLVSFLKKRIHCSCLDKKYKEVKSIPKLGLCCNTWCPLPCGKTERSLTKCCSRCRAANYCSRECQVAAWQGHKGECAFYADLKAKFESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DDW5</accession>
    <name>A0AAD9DDW5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sulfate permease family inorganic anion transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005339</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DDW5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052706">
        <property type="entry name" value="Membrane-Transporter-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43310:SF2">
        <property type="entry name" value="SLC26A_SULP TRANSPORTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43310">
        <property type="entry name" value="SULFATE TRANSPORTER YBAR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="362" mass="39158" checksum="A24A171F4466911E" modified="2024-05-29" version="1">MPSKSYGSVEDSPKPHPIHRHSSLLDSPSSPQTSASQFSSPLLRRFSERSPAGDTYMKASQSHDTSSVIQTPLLKGNGSTKQSAPTVEEGNSSNESSSTTFIGQVQDAGLIFLSAMSTTIATTMLEGQDANDTEVVSEIVSTTILVWERCWWYGKFRLADAVAYLPLPVVGGYLAFIGYFCLEAGVALCISHPIMKPSDWGYLFDDKSLLLATPGILAGIFLTLFLGINAGIGLGIITAILDFVLATANVSTIARVSRRSLAMWRPQERGILEATAYNPDRAQILTLEVRGAIFFGSSMKALGNILDESGINASTEEKKEIVMTNSPLPHHSRISRHSPSLHPPVFVKEGISEKRATSLMQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DE43</accession>
    <name>A0AAD9DE43_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Tryptophan/tyrosine permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_005534</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DE43"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003333">
        <property type="term" value="P:amino acid transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018227">
        <property type="entry name" value="Amino_acid_transport_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32195">
        <property type="entry name" value="OS07G0662800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32195:SF26">
        <property type="entry name" value="TRYPTOPHAN OR TYROSINE TRANSPORTER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03222">
        <property type="entry name" value="Trp_Tyr_perm"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="203"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="261"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="329"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="359"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="398"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="429"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="519"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="565"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="593"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1743937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="674" mass="72643" checksum="2A2F80332F0F4C07" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DE72</accession>
    <name>A0AAD9DE72_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DNA topoisomerase 2</fullName>
            <ecNumber evidence="14">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">QTG54_007035</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13 14">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="14">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Plastid</location>
            <location evidence="4">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 14">Belongs to the type II topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="14"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000819">
        <property type="term" value="P:sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03481">
        <property type="entry name" value="TopoIIA_Trans_ScTopoIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.30:FF:000001">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.670:FF:000001">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.199.10:FF:000002">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.670">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="entry name" value="Topoisomerase II, domain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="entry name" value="Topoisomerase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050634">
        <property type="entry name" value="DNA_Topoisomerase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001241">
        <property type="entry name" value="Topo_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013759">
        <property type="entry name" value="Topo_IIA_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013506">
        <property type="entry name" value="Topo_IIA_bsu_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001154">
        <property type="entry name" value="TopoII_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018522">
        <property type="entry name" value="TopoIIA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031660">
        <property type="entry name" value="TOPRIM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10169:SF38">
        <property type="entry name" value="DNA TOPOISOMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10169">
        <property type="entry name" value="DNA TOPOISOMERASE/GYRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00204">
        <property type="entry name" value="DNA_gyraseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16898">
        <property type="entry name" value="TOPRIM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01158">
        <property type="entry name" value="TOPISMRASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00418">
        <property type="entry name" value="TPI2FAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00433">
        <property type="entry name" value="TOP2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="Type II DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52040">
        <property type="entry name" value="TOPO_IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00177">
        <property type="entry name" value="TOPOISOMERASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 13 14" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12 13 14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 13 14" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="16">
        <location>
            <begin position="587"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="domain" description="Topo IIA-type catalytic" evidence="17">
        <location>
            <begin position="854"/>
            <end position="1308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="509"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="510"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="13">
        <location>
            <position position="944"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU362094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS52040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1742470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1317" mass="148204" checksum="D1C4028ABE3CBC30" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEP0</accession>
    <name>A0AAD9DEP0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEP0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="208" mass="23596" checksum="AAB0764CC6C2F0D1" modified="2024-05-29" version="1">MPPKKKTKLTRPQAAAAADEEADPAVVEQLDDNVIAIIFGCFPPEDTMRMRVVKYNAMRVVTTALPNLQQITICRLGNGHKYSDGEDPDEEMATAFAHFTTHDINIISNFRKLHRLNIDGAFMNGRYPALFNFPLLEKLRISLCCNFKWELEMLSGFPSLRELDVECNRSLRGNIGSLNVLKNSLEKVKIIDYNNVEGNFMDLLTFLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DF62</accession>
    <name>A0AAD9DF62_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF72 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1743894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DF62"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.410">
        <property type="entry name" value="Protein of unknown function UPF0759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002763">
        <property type="entry name" value="DUF72"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036520">
        <property type="entry name" value="UPF0759_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30348:SF4">
        <property type="entry name" value="DUF72 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30348">
        <property type="entry name" value="UNCHARACTERIZED PROTEIN YECE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01904">
        <property type="entry name" value="DUF72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117396">
        <property type="entry name" value="TM1631-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OTU" evidence="1">
        <location>
            <begin position="38"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="617" mass="68464" checksum="B53E51EFA44E3071" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DF83</accession>
    <name>A0AAD9DF83_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004323</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DF83"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1745032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="159" mass="17662" checksum="9CB35B5BCB833ECC" modified="2024-05-29" version="1">MSPPIMSDEEDDEEELLMAAAGQWAASAADDSGEDDSSAKKKSKKSMKSKQEKKEKKPKRDKPKEGSDASAAKIEQAPVNTEQNTTHQVFSLHLTKVPYEATQTDIRCAFSEKGCYVTSVRLVYDRKANGERNFRGVAFVDLGDEASFQKDSHYMALSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFS5</accession>
    <name>A0AAD9DFS5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_005117</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFS5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052420">
        <property type="entry name" value="Espin/Espin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153">
        <property type="entry name" value="ESPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153:SF8">
        <property type="entry name" value="FORKED, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="199"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="199"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="211"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1744584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="227" mass="24831" checksum="A3D5E74DD9913A59" modified="2024-05-29" version="1">MTPTEVLNSIAILLDFIDRQDWESFQSNALLSSAAFRAITNTIGNCPEFNGMTLLHAIVRCNPPLDVVAKMMDICPDQLAAKDCLGRTPLHVAAGSSAEPRLVKLIAHAYPASCDATDEDGKTPLHFACDSTCELFEDDANRTMPREICHDTIQALLSESLLAATIEDEDEMNALEYAIMSDAGLMTVRLLQKASYKTLQSISRSSTPRPAPEKRPRRVSDPAARVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGA7</accession>
    <name>A0AAD9DGA7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="7">3.6.4.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_004295</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGA7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055087">
        <property type="term" value="C:Ski complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070478">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000354">
        <property type="entry name" value="ATP-dependent RNA helicase SKI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="458"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="19"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="320"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="666"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="330"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="674"/>
            <end position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1745004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="781" mass="86212" checksum="2BFD9879AA54204E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGW9</accession>
    <name>A0AAD9DGW9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histone acetyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_003304</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:45948"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGW9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000123">
        <property type="term" value="C:histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1020.10">
        <property type="entry name" value="TAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013178">
        <property type="entry name" value="Histone_AcTrfase_Rtt109/CBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035898">
        <property type="entry name" value="TAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000197">
        <property type="entry name" value="Znf_TAZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13808">
        <property type="entry name" value="CBP/P300-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13808:SF1">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02135">
        <property type="entry name" value="zf-TAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00551">
        <property type="entry name" value="ZnF_TAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57933">
        <property type="entry name" value="TAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50134">
        <property type="entry name" value="ZF_TAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="14" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TAZ-type" evidence="13">
        <location>
            <begin position="218"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="51"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="95"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="142"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="155"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="169"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1745380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="310" mass="33453" checksum="75C9C35824B10994" modified="2024-05-29" version="1">MGYQYDPQLLLESGFTNETSQSAAAADSTNDQLDHRMSAVHPGDHVDVAAEEEKIKLPRTDRIPAAPITITEESEATMSSKREEEEGTFVSDVEDGTKKLAAKEGKGGAAAAAAAKRTSPPKESGLAGLKSLTKKSGADMIRLNEEGDAKELEEPSSATTDSSAISSSPKKDEAKSEQGKRGAKTAGPNFEQCNHQHEAIGVDKQGGGASSELTEEQRRERERSIRLHLTLVEHSSRCKSSFCGSSNCQKMKSYFKHVLVCTVKSSGGCKICKRTWALLRIHAQRCKNNACPVPQGIANKNGIRQLQQIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGZ4</accession>
    <name>A0AAD9DGZ4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HU family DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003648</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGZ4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13831">
        <property type="entry name" value="HU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="entry name" value="IHF-like DNA-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="DNA-BINDING PROTEIN HU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175:SF3">
        <property type="entry name" value="DNA-BINDING PROTEIN HU-BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="IHF-like DNA-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="156" mass="16993" checksum="707E1EA0D7CDAF60" modified="2024-05-29" version="1">MTSSFHHLSRSAALHISRKHCLRPAVSSVAPFRSYSSGFGGNHGFSTVTSNAPKDNGPVLSKADLAQIISAEHDLKMAESNRIIDTLLDTIVEAVSKEGTVSVAGFGKFFNKKLEARDYRNPSTGETVFKGDRKVPKFKAFTNFKDCVEGTKSVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DH91</accession>
    <name>A0AAD9DH91_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003709</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DH91"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042074542" evidence="2">
        <location>
            <begin position="18"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="517" mass="55362" checksum="DC8616AC4BD94287" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHD8</accession>
    <name>A0AAD9DHD8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">tRNA (guanine(37)-N1)-methyltransferase</fullName>
            <ecNumber evidence="10">2.1.1.228</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">M1G-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">tRNA [GM37] methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">tRNA methyltransferase 5 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_002766</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>guanosine(37) in tRNA + S-adenosyl-L-methionine = N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36899"/>
            <dbReference type="Rhea" id="RHEA-COMP:10145"/>
            <dbReference type="Rhea" id="RHEA-COMP:10147"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.228"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion matrix</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="10">Predominantly in the mitochondria and in the nucleus.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the TRM5 / TYW2 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.228" evidence="10"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHD8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052906">
        <property type="term" value="F:tRNA (guanine(37)-N1)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070901">
        <property type="term" value="P:mitochondrial tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002939">
        <property type="term" value="P:tRNA N1-guanine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.110:FF:000001">
        <property type="entry name" value="tRNA (guanine(37)-N1)-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.110">
        <property type="entry name" value="Met-10+ protein-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03152">
        <property type="entry name" value="TRM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030382">
        <property type="entry name" value="MeTrfase_TRM5/TYW2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056743">
        <property type="entry name" value="TRM5-TYW2-like_MTfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056744">
        <property type="entry name" value="TRM5/TYW2-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025792">
        <property type="entry name" value="tRNA_Gua_MeTrfase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245:SF43">
        <property type="entry name" value="TRNA (GUANINE(37)-N1)-METHYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245">
        <property type="entry name" value="TRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02475">
        <property type="entry name" value="TRM5-TYW2_MTfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25133">
        <property type="entry name" value="TYW2_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51684">
        <property type="entry name" value="SAM_MT_TRM5_TYW2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 10 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 10 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6 10" id="KW-0819">tRNA processing</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="SAM-dependent methyltransferase TRM5/TYW2-type" evidence="12">
        <location>
            <begin position="265"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="355"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="395"/>
            <end position="396"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="426"/>
            <end position="427"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="464"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1746159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="576" mass="65256" checksum="026F4AE228A436E6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHE8</accession>
    <name>A0AAD9DHE8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L13a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_001874</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHE8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_uL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_uL13_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1747911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="161" mass="17870" checksum="554F6FFFB6CC7147" modified="2024-05-29" version="1">MVLEKPIVIDCRDHLHGRLCSVVAKELLAGQKIVLVRCEDMVISGSLVRNQTKYAQFRKKRMNTNPSRGPFHFKSPAVWSGGLSVVWSTKSLIADKQPLDVFPPSRESPTLTTRSSVRSSLPPFVLSASSLDASTPRWVTSQQCWMEAPRACQQSRGQASC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHR6</accession>
    <name>A0AAD9DHR6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_000210</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHR6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="10"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="260"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1748271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="273" mass="29665" checksum="F3E0D04236010350" modified="2024-05-29" version="1">MTSRCSYSKCSTNNNDQASNNTAHLLGCSRCKSARYCSTACQKKDWVFHKFKCVSPEVTRHEVDGFSIEAIQSAINSASPGDIVVIKEGAYGNDGQSTLFVNKPIYLWGGEENRDNVVLDCNLVIDESDGDHDGSKAVVVADLFLDGTVTISDNSYKSVTLCNIELKCPNNSPRDALKISGCKGKCLILGCDIYGGSDGVHIASEQVYLKRTCIQYAQNRGIFSRRIFTIEDCEVSGCGGYGIKGSAGWTEKGRHNDIQPGPWSSDGPWSSGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DHS9</accession>
    <name>A0AAD9DHS9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Coatomer subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_001680</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle</location>
            <location evidence="2">COPI-coated vesicle membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DHS9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011710">
        <property type="entry name" value="Coatomer_bsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016460">
        <property type="entry name" value="COPB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029446">
        <property type="entry name" value="COPB1_appendage_platform_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040773">
        <property type="entry name" value="Rpn6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10635">
        <property type="entry name" value="COATOMER SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10635:SF0">
        <property type="entry name" value="COATOMER SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07718">
        <property type="entry name" value="Coatamer_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14806">
        <property type="entry name" value="Coatomer_b_Cpla"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18055">
        <property type="entry name" value="RPN6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="26S proteasome regulatory subunit Rpn6 N-terminal" evidence="14">
        <location>
            <begin position="4"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="11">
        <location>
            <begin position="436"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="11">
        <location>
            <begin position="701"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer beta subunit C-terminal" evidence="12">
        <location>
            <begin position="951"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer beta subunit appendage platform" evidence="13">
        <location>
            <begin position="1095"/>
            <end position="1222"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF14806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF18055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1747717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1245" mass="137255" checksum="C8627291A775E5DF" modified="2024-05-29" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2KVI3</accession>
    <name>A0A7S2KVI3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Macrocin O-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.101</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002833</name>
        <name evidence="1" type="ORF">SMAR0320_LOCUS5241</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.101" evidence="2"/>
    <dbReference type="EMBL" id="HBGZ01007364">
        <property type="protein sequence ID" value="CAD9586185.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S2KVI3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030769">
        <property type="term" value="F:macrocin O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008884">
        <property type="entry name" value="TylF_MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40036">
        <property type="entry name" value="MACROCIN O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40036:SF1">
        <property type="entry name" value="MACROCIN O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CAD9586185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="318" mass="36059" checksum="04DDA8B2ADB07FC5" modified="2021-06-02" version="1">MYSHLLLTNQANPIDTHHCTMILPTPTSSSSQECWQRADCRDLYREIIASKAVRVGKRGRGIRCAINSAWTVLGNDPTAQVLEFGVHTGRDMCLIDRCVRQKEAEQNTIRNARCAKMDMPPTQHQRVIHGFDSFEGLPEDWDNGQEGDYDKGKFDLGGVPPCLKEVQKHLNGMGYGIGKGKHKDAPDHGEVNNNIDETVVLHAGWFEDTVSSFFDDHPHPIGYIHADADLHSSTITFLEEICRRQLLVKGSVITFDEYANYPGWEKGEYLAWAQMVVKYNIDFQYIYYHSPSRGASVKELYNKHGYQSVTVVITKVPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2LYY1</accession>
    <name>A0A7S2LYY1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_010469</name>
        <name evidence="3" type="ORF">SMAR0320_LOCUS17610</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="HBGZ01024839">
        <property type="protein sequence ID" value="CAD9620284.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S2LYY1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042409313" evidence="2">
        <location>
            <begin position="34"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CAD9620284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1739153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="391" mass="44530" checksum="98176CFB9D10E7BC" modified="2021-06-02" version="1">MRLLRERTKYSHAIWLCLSLSMVSFFFLQQNSACNTFITNSESTNKKNDAMDDEPEATAGVEDYQPGSAEQYIMNNLDQLGFNKANNPATCHIWNDNETTTPEVYDSLVTYKKDIDRYNEIIEKFNPVPSTMDMIRQDQGGGGALQSIICDSLRLHPDGMQGIFPSKQLSFTSSGYVEPLLPPMRSHKICDNHSRNLMSLDYLVHDFEFMCKKLKPTSRLVLLDMGASLDFHGTAVTPIVTLLKQYEKFGFVFDHIYGFEITKKDPNVIYNTSLPEEYIPSYHWINVGVSSKEGDKLNPLHSIIKKLNEDDFVVVKLDIDTSSIEVPLARELLEDKDGVYSKIIDQFYFEHHVHLGELAGSWRSSMNGTVGESLELFSNLRKKGIPAHFWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2PL05</accession>
    <name>A0A7S2PL05_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Branched-chain-amino-acid aminotransferase</fullName>
            <ecNumber evidence="9">2.6.1.42</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_000197</name>
        <name evidence="8" type="ORF">SMAR0320_LOCUS11970</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="9"/>
    <dbReference type="EMBL" id="HBGZ01016728">
        <property type="protein sequence ID" value="CAD9605776.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S2PL05"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004084">
        <property type="term" value="F:branched-chain-amino-acid transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009081">
        <property type="term" value="P:branched-chain amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01557">
        <property type="entry name" value="BCAT_beta_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.10:FF:000004">
        <property type="entry name" value="Branched-chain-amino-acid aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005786">
        <property type="entry name" value="B_amino_transII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033939">
        <property type="entry name" value="BCAT_family"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01123">
        <property type="entry name" value="ilvE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009897">
        <property type="entry name" value="PRK13357.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42825">
        <property type="entry name" value="AMINO ACID AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42825:SF2">
        <property type="entry name" value="BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE 3, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006468">
        <property type="entry name" value="BCAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042409319" evidence="7">
        <location>
            <begin position="19"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR006468-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CAD9605776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1748258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="404" mass="44160" checksum="1BB208E5A61537E9" modified="2021-06-02" version="1">MRSLTAALALLLASSCQGFVAPSHNSHQIITTTTPSSTQLKKQPLSRLSVATDINAVGAPGTADLPWSELGFEFRPTKSHLRMTYRDGKWQEPEMVESPYINVHIGATALHYGQACFEGLKAFAHEDGSVNLFRPDENAKRINRSGHRVMMPEIPVETFIKACNDVVKDNVAYVPPYGSGGALYLRPLLFGSGPRIGLQPAEEYTFIVMVIPVGDYYKGGLAAPVNGLIVDDYDRAAPKGVGAAKVAGNYAADLIPNMAAKKKGFPICLYLDAATHTLVEEFSTSNFIGIDNENKKYITPKSDSVLPSITNKSLQTLAKDEGMTVEQRDIEVAELSTFDEVIACGTAVVVTPIGSLTRFDGNGEESKYQFTEDVGETTRRLYDTVRNIQNGEIEDTHNWNYKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRM7</accession>
    <name>A0AAD8XRM7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-hydroxyisobutyryl-CoA hydrolase</fullName>
            <ecNumber evidence="2">3.1.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_017037</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-methylpropanoate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20888"/>
            <dbReference type="ChEBI" id="CHEBI:11805"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57340"/>
            <dbReference type="EC" id="3.1.2.4"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.4" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000077">
        <property type="protein sequence ID" value="KAK1732262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRM7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003860">
        <property type="term" value="F:3-hydroxyisobutyryl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:L-valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045004">
        <property type="entry name" value="ECH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032259">
        <property type="entry name" value="HIBYL-CoA-H"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43176:SF3">
        <property type="entry name" value="3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43176">
        <property type="entry name" value="3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16113">
        <property type="entry name" value="ECH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl-CoA hydratase/isomerase" evidence="4">
        <location>
            <begin position="16"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1732262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="326" mass="35462" checksum="1C6EB86C4FAAD423" modified="2024-05-29" version="1">MSTTLQFLPSLSANLGILQLNNPASLNALTLEMIRSMTPILRQWQKTGVRATLMVGAPYEKNGKTKRSAFCAGGDVKKVYLAGIGKEDKSLTADFFREEYQLNHMIATQAPHLPQVSIWDGVVMGGGVGLVATERTIFAMPETKIGLFPDVGGSWWIPRLKLYSQWKSGLVGGVGNYLALTGNRLAAEDLIYAGIATHYVKSEKLDDLKSALAESTTSTSDDPNGDCVAGVLMSFHDHNVDTKSSFLSQNRADIDYAFDGKETMEEIIDALESMGEDSQFGQSTLNTLELMSPTSLKVTLEGLKRGAKLSSVGDALQWNTECRKHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSC1</accession>
    <name>A0AAD8XSC1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000056">
        <property type="protein sequence ID" value="KAK1732936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSC1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="235" mass="26449" checksum="ABF9ABC3CEE1088C" modified="2024-05-29" version="1">MVIKELVHSDRVNNKSLASIVLSAASSRKRDRCDAPESSSSCNATNSDDDDQDCSFFRSKKRVNSSVFNVSASATLSESREDISDGDDEELQELMLMHRTAVFREQRQLPETPYSMHFKDVEEDEEGLSPSFIGAHPTILRAKTITEDSSTDYIDPPEMSSRTHHTYEGHDSVFSELDETSSESYESRGLGEDTVNEREQPEWLSGSARPFAWTLPKKGSVPLFTSVQREISKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSW1</accession>
    <name>A0AAD8XSW1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cupin-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_016359</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000055">
        <property type="protein sequence ID" value="KAK1733028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSW1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF100">
        <property type="entry name" value="JMJC DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="3">
        <location>
            <begin position="172"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="276"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1733028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="451" mass="51564" checksum="90A8D876D184F75D" modified="2024-05-29" version="1">MMSSKKRPLPEPKDKDTHDVCKKNKSTTSAPPINQYDGWKVPSNNYTIPTISSQNNNTITPESFYNEYIRQRKPVVLRDMTTSSSPLLSDLSKLTKWKDINYLKSQVNPKQTVMVEQRSSCSNPTKSTFGNGYEIPMTFPQFASLIASGNDDRHYLTTQDVHSNSDGRPDLMSPLMKYLQHDFPLQPRIMGNLIPQNINLWMGSSREGVSSGLHHDYHDNLYIVIKGTKRFRLYSPHDTEWMYTRGKLGKVHPNGRINYQGEETTAFGADLKSDMAARAAKRKEDAEQMLEEAERAVEEGVEGADQLLEEAEVELEMAMDDIIDAEVDDDDDDNDDEKVYETFGDERKRVVDKTVKDPNNFSKVKPHMLDDTDVLTESYPDFLNATAAYCTVQEGDILYLPASWFHEVTSYGGQNGHLAMNYWFHPPDGESFEHPYSTDFWPNDYKDRFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTK0</accession>
    <name>A0AAD8XTK0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transcription elongation factor 1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_015654</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the ELOF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000046">
        <property type="protein sequence ID" value="KAK1733611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTK0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008023">
        <property type="term" value="C:transcription elongation factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.190:FF:000001">
        <property type="entry name" value="Transcription elongation factor 1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007808">
        <property type="entry name" value="Elf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038567">
        <property type="entry name" value="T_Elf1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20934">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20934:SF0">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05129">
        <property type="entry name" value="Zn_ribbon_Elf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6 10" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="83"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1733611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="164" mass="17646" checksum="3FA323C3A0198F2B" modified="2024-05-29" version="1">MGKRAKKAPVQTKKRQTLAKQFKCPFCANDEVVECKMDLKNGTGSLSCRMCSASYSMPIHHLHEPIDVFSEWLDDCEAAERGEVPVASAASGNGRSRGNMNKVVHDTSQDHYEDDDSVESEGLPEASGLGNKKRPAEQSGGGGGKKQKATTATLGLDESDDDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTQ9</accession>
    <name>A0AAD8XTQ9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AP2/ERF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_015958</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000050">
        <property type="protein sequence ID" value="KAK1733399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTQ9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51032">
        <property type="entry name" value="AP2_ERF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="169"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="79"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="20"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="36"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="89"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1733399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="267" mass="30114" checksum="D824B907C5E3B812" modified="2024-05-29" version="1">MVTKIIVRIPLEGRGRGRASASNSNRGDVQNSKQGDEDDKVDDSKEADEEGNSFKGCQRKAVDGGICAGHSSYHDVFFNDDTTEDDTTDDGKAVDISRHDNSKKRPHAWEDADDTKKKKRQPSCARVVIKHSAGNSGRERRNRLRLIDLSDVPAQPPILNSSGKDGTSKYQGVQFNKARDTWQATIVIDGAHHFIGYYDSEEEAAVDYARAVCKYHAKPLPPLIHPYAPTNLKEMEERQRRALAYSMMSDEDREKVRRQWNQGYVYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUQ0</accession>
    <name>A0AAD8XUQ0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015379</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUQ0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042037117" evidence="2">
        <location>
            <begin position="21"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="326" mass="34665" checksum="0A7FFB178E17EB18" modified="2024-05-29" version="1">MNNISYLAVLLASAAVGTQGKYLCSCSPTIFNFALDFSNDDCTVDTITGNPGVEVAMCLQEVVDAVPGQPASDEAISTSKFGRLRDDEHDQDELRSLQTADKVVEVVSAQFLEFSTDGVATVIHSDNTYITTSLLDGEAMQFFSVSSMLNSSVPLADQTENPALVPAGASLILYGKTESGKVIRNRFFWLYEMTNCGRDNKPVQVGDQIGWVKVEPGELGGAWPAFCPARQTASPTISPTISPRTKDPAHNPSSAPIEQIPTVTPSAKPVTTDAPSTGPSAKPIPDPSPREKPTHSVFGSKSTKSKSLKPPHSSKSSKSKSAKKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUV9</accession>
    <name>A0AAD8XUV9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_015150</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000041">
        <property type="protein sequence ID" value="KAK1734147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUV9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF188">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="97"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1734147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="483" mass="54436" checksum="EADD42425E42CCFD" modified="2024-05-29" version="1">MSKNGPTSADDAQSSEEFVQLIEFQLNKICQCKTFNLLSEEVLRELITRHGLKPNNNLNIRDYEFFLRACCNERVTEGIIRCLLEYFPDAGSFTSTDGKTPLHLICNNTNVTRSMVELLIDAAPNSVRIVTQLGWMPLHCLCLNRKLDDETSMEILKLLIQKCPQAVRHADYDTGFLPVHRACGSRAPDFCRVLIEAYPGSGRITASNGMLPIHIACTSNTVATVEYLYKLYPEVIHHKTANGVYPIHFAMKVKLQTIGGRISLLHFACRQQYTHPNIEAALEMIKVIYDAHPEAIEDSRIVSTFQYFHQQVQTFLNTQLAYSRQARDHRLMMTPDVNGQLPLHTALQSNVRLGSIKLLVKGNPSAIRTFDRSGLIPLHVACRHHDSTVVQYLVGLDTTTLDAMDREGNTALHCACLGAEFDTIALLLDKYDAVSVSKRNAQKKLPIDILWDSNAVVNRESVEYTESVFRLLKAYPETVMNIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUZ5</accession>
    <name>A0AAD8XUZ5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ankyrin repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUZ5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24121:SF32">
        <property type="entry name" value="DEATH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24121">
        <property type="entry name" value="NO MECHANORECEPTOR POTENTIAL C, ISOFORM D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13606">
        <property type="entry name" value="Ank_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="487" mass="54617" checksum="736C92D59D616D5D" modified="2024-05-29" version="1">MLSNELFMWSITNSLSEEGLHEVIERHELIPKIPLSKYQFFFAACLHKRVTEGIIKCLLQHFPEAASATDDDGWSPLHCACSNINVTPGILQLLIDAAPDSIRHADNEGRLPLHQFCMKDGRNEITALEILNLLLEKHPEAVRSANNKGDLPIHVATMMVRSPEFCHVLIQAYPGSERLTNNLGMLPFHRACMHNTVAVVEYLYKLYPDAINHATTEGAYPIIFAMGGKDDNRNSLTGAVRIVQFLLNLDPNVARQKIDGFCLPLLWAIHLKCNDSNVKALIEIIKMIYDAHPEAIYNEDVLANLEHGHRQVRAFLDTQMFYSWQARFHRLMATPNYYGQLPLHTAVQNNDAATPGSFKLLVKGNPSAVQSPDNEGALPSHVACQHHDSVSVVEYLLGLDATTLYAVDTNGDTPLHCACRGAKFETITMILEKYDAVSVSKRNAQKKLPIELLWESDEVLDRKSIEYTEIVSQLLKAYPETWMSIGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVP8</accession>
    <name>A0AAD8XVP8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">KA1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014612</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVP8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001772">
        <property type="entry name" value="KA1_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50032">
        <property type="entry name" value="KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KA1" evidence="2">
        <location>
            <begin position="180"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="505" mass="55199" checksum="943ADBA81E18E36A" modified="2024-05-29" version="1">MSDHQQNKTQRNNEQKIQLDEHSSSPSLASGGRGSIPPSEQQPAMRSVAINPAASQHRTLLFNPPFKRVDPGTTAMAPLKTTMPTSTAKQPPQYVDTRPMITRKSLSDPLIGAATKWNVQHSNLKARPSPTPTTPCALPPPQKCTSRLVKFTSADIISGRIAMTLQARSIKAKYCKSAAKCRTLDFVKFYIRLYVVPGDDGGVLVELQRVSGDYLSFMYDCRAILDAAEGKDVIMESNEYNSKAMYLRLPVSQMSFVCNDDIVLEHDLKTTQDEEDIINITSELLSSPQSDSNMLGMESLVSLVDANLTSKSTAILAAKRLVCTRHESGNGPFSLHNYAMSLIIYEDDHENDDEDDSSLEEDATSLSMKVSLNRSIAEHTRRLRTHALMAISNALDLLNSEKILCDTISASKEWYALVLIPSLIDNVKSASSKPYDATLAARCLTSLAMCSKVFASTMKNSEGCKNAGGGGGCLSALESAGQIGRDEFELLLRDVERCQSTLLGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVZ2</accession>
    <name>A0AAD8XVZ2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014758</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000038">
        <property type="protein sequence ID" value="KAK1734510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVZ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="209"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1734510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="234" mass="25328" checksum="B38470D67A3BA1B8" modified="2024-05-29" version="1">MSFDCSGNTIFTDLELDYSDDNVLLATITADAEWKNNTQASLTATMGDVKVLEEKFELCTYLTEESVACGDAGNVTLDLSSIAVPRAGATSETMASLISSSYIEFKAKPSGKNKEKCIKSPISTTSHLFSFSHSPLTSESAFKLELLLGMIALVALVGLAAFAYKRSKISVGILRVKRIPNGIRITRSRSGRSLSRSRSGRSRSRSRSSGRSITRSTSSKSLEQKLYEGEEGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW03</accession>
    <name>A0AAD8XW03_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_014977</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049227">
        <property type="entry name" value="DUF6824"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20710">
        <property type="entry name" value="DUF6824"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6824" evidence="3">
        <location>
            <begin position="8"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="2">
        <location>
            <begin position="486"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1734470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1496" mass="163992" checksum="BC5FBD06FBA2A8A4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XW64</accession>
    <name>A0AAD8XW64_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein pelota homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_014953</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the Pelota-HBS1L complex, a complex that recognizes stalled ribosomes and triggers the No-Go Decay (NGD) pathway. In the Pelota-HBS1L complex, pelo recognizes ribosomes stalled at the 3' end of an mRNA and engages stalled ribosomes by destabilizing mRNA in the mRNA channel.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the eukaryotic release factor 1 family. Pelota subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000039">
        <property type="protein sequence ID" value="KAK1734446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XW64"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070651">
        <property type="term" value="P:nonfunctional rRNA decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070966">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, no-go decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070481">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, non-stop decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032790">
        <property type="term" value="P:ribosome disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071025">
        <property type="term" value="P:RNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.870:FF:000001">
        <property type="entry name" value="Protein pelota homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000008">
        <property type="entry name" value="Protein pelota homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.60:FF:000002">
        <property type="entry name" value="Protein pelota homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.60">
        <property type="entry name" value="eRF1 domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.870">
        <property type="entry name" value="Pelota, domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042226">
        <property type="entry name" value="eFR1_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005141">
        <property type="entry name" value="eRF1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005142">
        <property type="entry name" value="eRF1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005140">
        <property type="entry name" value="eRF1_Pelota-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038069">
        <property type="entry name" value="Pelota/DOM34_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058547">
        <property type="entry name" value="Pelota_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004405">
        <property type="entry name" value="TF_pelota"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00111">
        <property type="entry name" value="pelota"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10853">
        <property type="entry name" value="PELOTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10853:SF0">
        <property type="entry name" value="PROTEIN PELOTA HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03464">
        <property type="entry name" value="eRF1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03465">
        <property type="entry name" value="eRF1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26356">
        <property type="entry name" value="Pelota_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01194">
        <property type="entry name" value="eRF1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159065">
        <property type="entry name" value="Dom34/Pelota N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="eRF1/Pelota-like N-terminal" evidence="8">
        <location>
            <begin position="8"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="395"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="395"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1734446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="424" mass="47900" checksum="30B3AEEF4BFEF389" modified="2024-05-29" version="1">MGAYETTMKLIKKFISAKDGSGSVTLLPQSPEDLWHTYNLLQTSDHVRCTTLRKVTKESSTGSVTSNKVRMNLTIEVTKVEFDKESLQVRISGPNSAESQHVRMGAFHTLTLELDRQFTIEKECWDAIFLDRIEEACNPEVGAEVACIVMSGGLAHVCLVTGSVTVTKARIDMNIPKKRTGSSGHSKAIIKFYDAIYRAILNHIPFDKIKCVLVGSPGFQRDDFFKYLVAESVRRDDRVLIKSKEKFVLCHASSGHKHSIEEMFSDPNIASRVTETKLVKEVEALNRFMRLLDTHPDKAYYGFGHVQKANEELAIDTLLITDELFLSSDVVTRKNYVVLVESVRERGGNVYVFSTMHVSGQQLQQVSGVAAILRYPLPDLDELEDIAANHEAYAEYESDDELTEEEKRQKEEARMREEMKDMGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWV8</accession>
    <name>A0AAD8XWV8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sel1-like repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_014450</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000036">
        <property type="protein sequence ID" value="KAK1734990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWV8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="341"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1734990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="640" mass="72389" checksum="932514F0F795DA85" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XX88</accession>
    <name>A0AAD8XX88_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_013982</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XX88"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1735368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="160" mass="18648" checksum="DA9B5BCAD9817C98" modified="2024-05-29" version="1">MFLTETSSGFMASTSSVSSMLKIRHNFPILFMEESNNSSDENDADSESSDTNKENVVIEDLSWRVAKARLEEEASKRSFLKRKPLKLSYEQSQKWIQRNWAIKTEEEFNDLVANGNLRTPYISKRPEEYYGERGEWISWDHYLTGNCTDSIAEGRQSKWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXR9</accession>
    <name>A0AAD8XXR9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mitochondrial import inner membrane translocase subunit TIM22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_013801</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the TIM22 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Mitochondrion inner membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the Tim17/Tim22/Tim23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXR9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042721">
        <property type="term" value="C:TIM22 mitochondrial import inner membrane insertion complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030943">
        <property type="term" value="F:mitochondrion targeting sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045039">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039175">
        <property type="entry name" value="TIM22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14110">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14110:SF0">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="68"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1735638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="272" mass="28489" checksum="83509C7D32F143D9" modified="2024-05-29" version="1">MSSSSPSSASEEAQQQQQQQQSTSTYQPPSIYQSIMSGSTSLSSAHYTAQGALHQAVQLYGSNEVTNTPAGPLINSNENDDGSSTQSAKNSSNNNLNNNLTLGALTMRALPYPQPWSPSNASPAELPPNFDWLSESCGGKAAIGIIGGGVMGLLMGVFMGALTDMTPPVTIIEGKEVPQAPLKEQVRTTLRATADKSLYWCRQFAFITGVFGGSECLVEKYRGKHDVWNAVVSGCVTGAAMQAKQGPQASAVGCGGFAVFSLVIDSVMGTHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XXY0</accession>
    <name>A0AAD8XXY0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_013428</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XXY0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13405">
        <property type="entry name" value="EF-hand_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="12"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="153" mass="17497" checksum="ACF18E75C8A5C139" modified="2024-05-29" version="1">MIYEFLGGIGEYSRSDIEALFHEIDSDGSGFIDRDEFDNFIGIITTERNLSTLSMSQRELVGAMEKSQMRRRSKITSSAHRSMHHTTNHLLGDSYTIDYMCNLLKNSEDVDNPLEDWSIFYCGGSSKMKDDLKKQSRRSTLLTSLLRNLIGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XY68</accession>
    <name>A0AAD8XY68_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-directed RNA polymerase III subunit RPC5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013738</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XY68"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006886">
        <property type="entry name" value="RNA_pol_III_Rpc5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12069:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12069">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES III 80 KDA POLYPEPTIDE RNA POLYMERASE III SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04801">
        <property type="entry name" value="RPC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="474" mass="52871" checksum="E31FFE3081F39FBB" modified="2024-05-29" version="1">MMSPRPESVISSSAAFSPIIPDDDEDPIIRSIDVFISPELSRTLHLLQFPIQPVITSASSSSNNNNSSKATTPIEAKLRPKHNMLELEYPIPNSALGGHSHQQADSIHLTQRTFTSNAIAPVTHMALAKLDKAGERLDIIPLQKDVLQMRPSFKHLHNHEEEDDTQTNVEKAGDSNTTISGKQKPILFQKKESDRSASARRNSYAHKKASEESEEWIELDVHGSEGKWSSVRKDELRKIVCANREQTIQLAKSKFTDGDGGHYVRSLNYMESISSAFADPADMMVMGEPTSESTTTAGEDVDETAVAELASKLVVLLQEGLGKMIPFSVLRSNFHTEKVSDEMLIMALSSCAVLVRGNFALKSSLAQFLKKDVMKEMRDLMMLLLNMHGSIQRERLVRAFETKASTDDDYAVINADIITFVLETMAKLLNGCWVSKVPDDVVFAAKFPKFAACHGVYWMRKKKMLKELVELYEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYC0</accession>
    <name>A0AAD8XYC0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">SYG1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_013433</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SYG1 (TC 2.A.94) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYC0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000822">
        <property type="term" value="F:inositol hexakisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016036">
        <property type="term" value="P:cellular response to phosphate starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004342">
        <property type="entry name" value="EXS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783:SF103">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 53 MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783">
        <property type="entry name" value="XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03124">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51380">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="460"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="503"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="574"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="608"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="668"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="707"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="760"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="896"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="9">
        <location>
            <begin position="2"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="EXS" evidence="8">
        <location>
            <begin position="666"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="121"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="317"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1735727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="938" mass="108030" checksum="84CFFE79ABFAE4A1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYR5</accession>
    <name>A0AAD8XYR5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_013235</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYR5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1736099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="69" mass="7727" checksum="C572CE6DEC47DF6E" modified="2024-05-29" version="1">MCTSQRLRKISLQVLARLLIMRFELDVSELAVEPEIERFVKSIVTFAASGGKEFVVEVVGNDGVVELFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZ07</accession>
    <name>A0AAD8XZ07_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Solute carrier family 35 member F6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_013208</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZ07"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13146">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08449">
        <property type="entry name" value="UAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="413"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="449"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="474"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="102"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="179"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="120"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="182"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="196"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1736072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="504" mass="54975" checksum="E1A2121F9CC4654F" modified="2024-05-29" version="1">MYSAKVSFILGAMVLTGAARSVTAKIFYQLGFNHPLFLTLLYLIGQALSLIPYNIMVLLKKRGYRLVWDDHAILPGLSNRIEEEESVSIPSRHTVRTRQTLRYTTPDDEMERAESMASLDENKANNHDVESQRRKSTVSVRFASEECTNTSRAARASISFADGTKESDGAGAVMEDHLEAQGKSSTSLDPGSTSEKMAKKPSLLDRAKSARMSSKTLDTARRISASTHGLPTHSRTRSCHANIPWYLKPAVPAFFNLLNSAMRWASLVHVAASVAEMLISGMELVLSVCATRLVRGRKITWVRWVGVLVVTLGIVLVGVFDTNNVAGGETNDESTVNKQIIGILLILGQSVMSVIQDLTEEVFMQETAFPPPLLVGMEGAYGIVIALILYFPIAPLLGENPSDVASSLSEGNVIALAIGWTLLVTVTGIFNIAATAVTSSMTRNVWKNMRTLLVWIMGLILFYATGSSELGEGWYIPGSFFILLSYGVMCVGIFIYYGKGARAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZ11</accession>
    <name>A0AAD8XZ11_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Trigger factor ribosome-binding bacterial domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_013204</name>
        <name evidence="3" type="ORF">QTG54_013898</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000034">
        <property type="protein sequence ID" value="KAK1735284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZ11"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1050">
        <property type="entry name" value="Trigger factor ribosome-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008881">
        <property type="entry name" value="Trigger_fac_ribosome-bd_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036611">
        <property type="entry name" value="Trigger_fac_ribosome-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05697">
        <property type="entry name" value="Trigger_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102735">
        <property type="entry name" value="Trigger factor ribosome-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042442420" description="Trigger factor ribosome-binding bacterial domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Trigger factor ribosome-binding bacterial" evidence="2">
        <location>
            <begin position="78"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1735284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1736068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="207" mass="22091" checksum="56B88D267CADF84D" modified="2024-05-29" version="1">MKLSVPLFLGLAAQATAFTTFSSQSTIIPSSPTSLYAAELTPEPEGGEELTKVTSSMEGSRMKNMGAGDDEGVYKFWLSATADGAQIKKVRTTTEKEASRKANFPGFRKGQVPPYAQPQITGFAVQEAIIKTCEQSLEAYGLESLSGSAGEVTVNEDVKDICKGYKVGTDVSFTATYMGKFDANIHTESATEEAEDDSVVDVEVVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZ28</accession>
    <name>A0AAD8XZ28_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012958</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZ28"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="243"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="600" mass="64765" checksum="04023B0C485C2C4F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZ34</accession>
    <name>A0AAD8XZ34_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Serine/threonine-protein kinase</fullName>
            <ecNumber evidence="10">2.7.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_012864</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="10"/>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZ34"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:001660">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF140">
        <property type="entry name" value="INACTIVE PROTEIN TYROSINE KINASE PTKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="188"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="390"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="491"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="286"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="531"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="69"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="348"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="518"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1736264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="815" mass="89176" checksum="400D981852BEB383" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZV7</accession>
    <name>A0AAD8XZV7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZV7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="426" mass="48699" checksum="5FAAAEF48C48CD7C" modified="2024-05-29" version="1">MATTVSPNNSMPKPFSHQIGNMPFEKAHAVIASPRMPPTTMWQVDKTCASGKLKPKRPYTPYNLFYLLERELVVQKINGPPKSNGIKRKHVGVAPREEDQIKPSSRYDGIVFKPYWYDPDMKEKRKHRKTHGMISFKELTGIISANWATVDKETKDYVTIISELGRKRYKDKMNLFNASQKIIQLKKEHAEADTGKKMSGNLKKQPTASKLVHMGSPVRRNVASMKGKPIPVTPDRTMSNLPQIAHKPSPSVAIPHGYHHHHHPNLPIMYPHRYGITQLPPPLPPPMPTTMSPPPNMPSPYQHRPRQFECNRPVKIPKKDSKEDSMKDSNLKVEKDDTISSSREAKIPHDEALHINSLMDHEFMDFEPDHITEDVFDHDNIDVFASPATAKNVEDEDILDMIKGDVWNLDMDNFNYDDEPFKFLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y133</accession>
    <name>A0AAD8Y133_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">pyruvate dehydrogenase (NADP(+))</fullName>
            <ecNumber evidence="10">1.2.1.51</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Pyruvate:NADP(+) oxidoreductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_012441</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>pyruvate + NADP(+) + CoA = acetyl-CoA + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17425"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.51"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">In the N-terminal section; belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.51" evidence="10"/>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050243">
        <property type="term" value="F:pyruvate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07034">
        <property type="entry name" value="TPP_PYR_PFOR_IOR-alpha_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.20:FF:000022">
        <property type="entry name" value="Pyruvate:ferredoxin (Flavodoxin) oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.920:FF:000007">
        <property type="entry name" value="Pyruvate:ferredoxin (Flavodoxin) oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000012">
        <property type="entry name" value="Pyruvate:ferredoxin (Flavodoxin) oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000041">
        <property type="entry name" value="Pyruvate:ferredoxin (Flavodoxin) oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="entry name" value="Pyruvate-ferredoxin oxidoreductase, PFOR, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050722">
        <property type="entry name" value="Pyruvate:ferred/Flavod_OxRd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019456">
        <property type="entry name" value="Pyrv-flavodox_OxRtase_EKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019752">
        <property type="entry name" value="Pyrv/ketoisovalerate_OxRed_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011895">
        <property type="entry name" value="Pyrv_flavodox_OxRed"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02176">
        <property type="entry name" value="pyruv_ox_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32154">
        <property type="entry name" value="PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32154:SF0">
        <property type="entry name" value="PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10371">
        <property type="entry name" value="EKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01558">
        <property type="entry name" value="POR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01855">
        <property type="entry name" value="POR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00890">
        <property type="entry name" value="EKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="Pyruvate-ferredoxin oxidoreductase, PFOR, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="14">
        <location>
            <begin position="760"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="14">
        <location>
            <begin position="818"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="domain" description="Flavodoxin-like" evidence="13">
        <location>
            <begin position="1283"/>
            <end position="1422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00053024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00061065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00067011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00076877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1736996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1588" mass="175966" checksum="6F4C8D815E35E773" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1A5</accession>
    <name>A0AAD8Y1A5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011538</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1A5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041899197" evidence="1">
        <location>
            <begin position="23"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="152" mass="17000" checksum="B204645435FC943D" modified="2024-05-29" version="1">MKVQLFASTALMLLSAIPGALSAEHKHLHLKEAVAATAAESEKSPSAKSFSLRGAVAVASAEDAADEDEGLIQYGWYRNRDWSSNPYTGKRWGSEWQNGDNGENQVPTYTTPKYTTPKYTIPKYTTPYYHGSHYPRTGKLMERILWRNNVTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1D9</accession>
    <name>A0AAD8Y1D9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012142</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1D9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="242"/>
        </location>
    </feature>
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        </location>
    </feature>
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            <end position="518"/>
        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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        </location>
    </feature>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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        <location>
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            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="436"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="486"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="672"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="810"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="820"/>
            <end position="832"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="832" mass="90188" checksum="03321DA509212AC4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y201</accession>
    <name>A0AAD8Y201_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3119 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y201"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021467">
        <property type="entry name" value="DUF3119"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35550">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35550:SF2">
        <property type="entry name" value="OS05G0401200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11317">
        <property type="entry name" value="DUF3119"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041919313" evidence="1">
        <location>
            <begin position="23"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="226" mass="24286" checksum="44965CA16B6222E4" modified="2024-05-29" version="1">MITMNLLKSSLLLLISSTSVQSFTTTPSPLASVPRNTKKAVDLARPTTSKTTSTSLAVGTEIVEPSYNLALGSLALGAAFGVPGSPLKSKLSAFLGGIPLTLFGLFLAFQTTTLRFTLDDDNFSLVKSNLESTGENVVVGGENVWSYKSFVNYDVFPSRNFPILIYFKETQTPEDQWNIGPGEQANSEEALAKGAVRGQVHFFPAIGNTEQLIGGFEKHDCAKLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2A4</accession>
    <name>A0AAD8Y2A4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_010887</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2A4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861:SF1">
        <property type="entry name" value="TRANS-ACONITATE 2-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861">
        <property type="entry name" value="TRANS-ACONITATE 2-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="4">
        <location>
            <begin position="403"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="97"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="177"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="116"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="211"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1738218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="583" mass="65566" checksum="B0EBB670E7D72CAF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y2Z5</accession>
    <name>A0AAD8Y2Z5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">C2 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010623</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y2Z5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010628">
        <property type="term" value="P:positive regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47800">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47800:SF5">
        <property type="entry name" value="FER-1-LIKE PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="1">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="131" mass="15095" checksum="F744B75170C161F1" modified="2024-05-29" version="1">MGVLTIYLDKATNLKNEDTMGTSDPYIKFSLEQDNMIKDKDYGDMKSSVKKNDLNPVYGETFHFNIPSLNNMELTVKVMDDDIVSDDKMGKSKIKLEKHGLNATPKEFKEKVYNRVFGKDAYVHLTLKYEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y364</accession>
    <name>A0AAD8Y364_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclin C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y364"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042094528" description="Cyclin C-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="32"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="171" mass="18324" checksum="5F075C7362656FD5" modified="2024-05-29" version="1">MLQTLGWRLNPIVPSGCVIELLVMFLPCAMDSEHDGGSGGESSRQSVVQNFVYDCATYLTELAVSVAALSLVYKPSVIAYASVLAAVDLLLEDDSSSMSSSSSSSRVTEDTLIEYDALLNQASCQHFERNKDEVVKAKEILGVMAPNVGLLFPSPFGEPTPTTFVGPNELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3K0</accession>
    <name>A0AAD8Y3K0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_011081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3K0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1738412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="98" mass="10903" checksum="1EDAEDE0ECAEB865" modified="2024-05-29" version="1">MSAAACDLERDDDDSCSSHEFDFAEQADKTYVPATVNTKTTTATKTASALMVAASAKAGMEDIDRERINAILLRESGNSSFRRGNEKWMRTATNEYWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3U8</accession>
    <name>A0AAD8Y3U8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3U8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052201">
        <property type="entry name" value="LRR-containing_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24111:SF0">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24111">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="492" mass="54565" checksum="19E70BC476D8EE0B" modified="2024-05-29" version="1">MLVTKNPAQYITALEEDITDALQIGLLFSGQISDTHAASLLELASAIQSTPRSIRCLCLRFKDDVDESTMSSFLYFGQMIVSAKAIESLVLEGVGVGHEQIVCLQEFLSTNKTLRGINFTETKLDRSSSILLTGFLTGNASLRVLDLSSNARVDDDSIDTILTAISLGGSQLSTLNICDAHFDGVEDLIGDNGSITTAGVRTITAFISQTPSLVTICLKMRSLNDEGIRDLSNVIRRRDSKISRLEISGTFGNDALQSIAEALKSNQSLRTIDIGNSLNLTDEGGRAILRVASVNVVNTWKQIMASNNTLRSAYLKSRPPPLLVSQDIQHALRNITNVDPIPTLKQKVWRYVDSNIEDLSYTKLEAKHMPFLLSFVKERGGINSLFRLISSRNNVPILFSHPTPERQHMESIMNKVALENATLRAMLKSERQFNDILYKENNSLRSLYEGDIADDETVTTTIMTPLLPEESDNRRCLCCRRGPISNLWECFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6H9</accession>
    <name>A0AAD8Y6H9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Shewanella-like protein phosphatase</fullName>
            <ecNumber evidence="2">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6H9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46546">
        <property type="entry name" value="SHEWANELLA-LIKE PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46546:SF4">
        <property type="entry name" value="SHEWANELLA-LIKE PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="159" mass="17241" checksum="8680F1543FBBACCF" modified="2024-05-29" version="1" fragment="single">RPDLPKGQRIVAFGDVHGDITALRAFLVTAGILDPRSSIEEPVWCGGTTICVQTGDVLDRGDDELACFRLLATLARQAHDAGGQLLLLYGNHESLNAAGLFQYANPGGNVEFERTIGQGIDYNYGSNRWRLQFAGNQPSRWASFEPGGLLSETCWGICS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6I6</accession>
    <name>A0AAD8Y6I6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_009683</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6I6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="385"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1739924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="433" mass="48539" checksum="59D07092C74A1458" modified="2024-05-29" version="1">MTISTAQSNLKPSCVKKSTSVKKVRGRDAVPFEEMERLMNLYGSIKALRIRGAAKKKGSAKEGDKKVSVKKDSIKRKFYRWFPNFEERFTIDENGHYQPVNGHEYEMKYRAEMRQKSMTVVVNKRSDSITKKKYGQNEKIAERKDATKKGNVLSRQVSSSGSSSSSSSGSSDNNIEADIGITIPDDIEIDRSNIVMPSPTTIPTGNNKNSSFLNNGHRAPSPLSFQEQPTKKAVSEEQDTMCSFVSQDSEEAGIAASEPELKTLFDFDEVDKQYYGEAMSMMQSYDPMPMMQSYDPMPMMHSYEAMPMMNSYDPMPMMNSYYDPMPMMNSYDQMQQMSELSALSSMLNSYPAMPMMNSHAAMPTMPMNSYDQCFSCRLSDDSLQGSTGMVSDSSSSGNSSLNLNEQWGSDSDIEDCLFLGVGNEMLSTRPSFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7B7</accession>
    <name>A0AAD8Y7B7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">NFYB/HAP3 family transcription factor subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_008366</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NFYB/HAP3 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7B7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016602">
        <property type="term" value="C:CCAAT-binding factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22907">
        <property type="entry name" value="HFD_NFYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000110">
        <property type="entry name" value="Nuclear factor Y, subunit B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027113">
        <property type="entry name" value="Transc_fact_NFYB/HAP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003956">
        <property type="entry name" value="Transcrpt_fac_NFYB/HAP3_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11064">
        <property type="entry name" value="CCAAT-BINDING TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11064:SF9">
        <property type="entry name" value="NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00615">
        <property type="entry name" value="CCAATSUBUNTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00685">
        <property type="entry name" value="NFYB_HAP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0010">Activator</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="9">
        <location>
            <begin position="47"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="135"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="142"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1741114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="184" mass="19466" checksum="8532606288509F96" modified="2024-05-29" version="1">MQPNNPPPPVGLHGGPPPTFSTTADALAAARMPPGDEYEEIREQDRYLPIANIARIMKNNLPENAKIAKDSKETVQECVSEFISFITSEASDKCMQEKRKTINGDDLLWAMSTLGFDKYVEPLKLYLGKYREAVRGDKPEKGGGASGSGGGGAGSGVGRPPATAASAGDGVGVPPPSKKTKKDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8I9</accession>
    <name>A0AAD8Y8I9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_007362</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 5"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8I9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000006">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.460">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000774">
        <property type="entry name" value="PPIase_FKBP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036944">
        <property type="entry name" value="PPIase_FKBP_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43811:SF19">
        <property type="entry name" value="39 KDA FK506-BINDING NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43811">
        <property type="entry name" value="FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01346">
        <property type="entry name" value="FKBP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="6">
        <location>
            <begin position="203"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1741789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="290" mass="31338" checksum="4BEB0249BC353778" modified="2024-05-29" version="1">MMSQRQLATRFHRSFLSSASIASGRRKTNIMRINMSSLTALLVASSSRAVSAFTTRTVAPVAARAAMTTRHMASGPMASGPMPYDDEKMPIYALGLNIGMQISSQTDFKTLLEEDELAILLNGFEDVVKGENTANPMEVLQKYGPAVNELLRDRTEKIVERVKKDGEEYIEGFLDCNDEAVKTDSGLVYYSMKEGDGASPEVADEVEVHYHGTLVDGTVFDSSVERGATIKFKLGQVIKGWQEGLAMMKEGGKATLVIPPGLAYGDAGSGGAVPPGATLKFEVELFKVNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9E9</accession>
    <name>A0AAD8Y9E9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Histone H2B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_007947</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the histone H2B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9E9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22910">
        <property type="entry name" value="HFD_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000014">
        <property type="entry name" value="Histone H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000558">
        <property type="entry name" value="Histone_H2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055333">
        <property type="entry name" value="HISTONE_H2B_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23428">
        <property type="entry name" value="HISTONE H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00621">
        <property type="entry name" value="HISTONEH2B"/>
    </dbReference>
    <dbReference type="SMART" id="SM00427">
        <property type="entry name" value="H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00357">
        <property type="entry name" value="HISTONE_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="10 11" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="13">
        <location>
            <begin position="119"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1741469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="224" mass="23440" checksum="256566550DF92A97" modified="2024-05-29" version="1">MDVRKDTSRGNGNSSKQLVQLLIVLDGKGDVTGHNTSLLVVTGGIASKLEDLGTEVLEDGGEVDGGSGSHTGGVLALTEVTADTTDGELQSSLGGGAALLLISNMAKTPSKKAPSKAVKKASTEGTKKRSKKRVESYSTYIYKVLKQVHPDTGISKKGMSIMNSFINDIFERIAGEAGKLATYNKKATLSSREIQTAVRLMLPGELAKHAVSEGTKAVTKFSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9V9</accession>
    <name>A0AAD8Y9V9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_007461</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9V9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097272">
        <property type="term" value="P:ammonium homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3430.10:FF:000016">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11730">
        <property type="entry name" value="AMMONIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11730:SF6">
        <property type="entry name" value="AMMONIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111352">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="206"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="290"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="324"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="351"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="423"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="9">
        <location>
            <begin position="52"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1741888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="558" mass="60585" checksum="9A5123E6B17C7D21" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAA5</accession>
    <name>A0AAD8YAA5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">CobW C-terminal domain-containing protein</fullName>
            <ecNumber evidence="8">3.6.5.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_006343</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAA5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03112">
        <property type="entry name" value="CobW-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1220.10">
        <property type="entry name" value="CobW-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051316">
        <property type="entry name" value="Zinc-reg_GTPase_activator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748:SF62">
        <property type="entry name" value="COBW DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748">
        <property type="entry name" value="COBW-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90002">
        <property type="entry name" value="Hypothetical protein YjiA, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW/HypB/UreG nucleotide-binding" evidence="6">
        <location>
            <begin position="12"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="CobW C-terminal" evidence="7">
        <location>
            <begin position="261"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00034320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1742746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="373" mass="42281" checksum="A51869D4EE50CB15" modified="2024-05-29" version="1">MKRKMEETKKIPVTVLTGFLGSGKTTLLNHILNDNTHGMKFAVIENEFGEIGVDDKIIPEAVDEEVIEVMNGCICCTVRGDLVEALKRLHKRMDKFDGVIIETTGLADPAPVVQTFFVDEDQLFTAILLSMCLTIIFKLLTDPVTLLCTLSFRHSDHVFSRFGHHRCGCQGDPRQACRGEARGVENEAVEQVCFADKILLNKTDLADETKLKKIEGEELLNIRAFDLKRVLDFDPEFLDPDQEHEHDATSLQFHAVSRGVEEKFIFQGVGMLFDGNISDMKWNVPESERENIFVFIGKNLDHQWLRDCFEACIVSDQLRFKVGDKVQANIGEYTNGTIKKLWDDGNAYRIELDDADKTNVYAPIDVDTYVKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAC4</accession>
    <name>A0AAD8YAC4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_007264</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAC4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1741691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="188" mass="20508" checksum="E15F81FE6E5C47AC" modified="2024-05-29" version="1">MPTIGVGEPDAPMSSALGTMNGTWRLDKLRGKPSMRGYLETMGVPELAIEAHEKGEEDHETIHTIEFSDSHFKIKKQSRVTDMGLDLKLGEECLANLPGDRVKTTIATTENPGQQVKIVSRMPTMNGMANVVDTKTLQREGNLLVLVQTLTIKNELSGKEHTTTRYFVPHEGALIPLAATAKGSVGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YB61</accession>
    <name>A0AAD8YB61_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pectinacetylesterase-like protein</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007684</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YB61"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004963">
        <property type="entry name" value="PAE/NOTUM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21562">
        <property type="entry name" value="NOTUM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21562:SF83">
        <property type="entry name" value="PECTIN ACETYLESTERASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03283">
        <property type="entry name" value="PAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042117623" evidence="2">
        <location>
            <begin position="21"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="482" mass="52968" checksum="96322A810CE9348A" modified="2024-05-29" version="1">MNMKQRIATFLLLSAAMANGDDSTIISYKNCDANSLPAENTSISTLNNGQFYKMCPGSHKHSNNDTFATLGQPKCGDGSNFAFYLTRPEQPQQGEQPQKVLIELSGGGACWDKGTCALQSFFLKMPPLDFVLGMSCSDVGKIAEVSEGWDILCARTVGETDFTEYNTIVIPYCTQDVHLGDAAEALYDGTTIQHVGGHNTYRTLQWVFDNFEDPSHIVLTGCSAGATPLPVFYHMIKEHYKARGRNVKVNIISDSPVYLTPRNFLENHFQFWNHETVMKSIGFDYDTHKEDVQYASAVLDYVLDGSDDSDGIGVVSHNDDAISLMYYIAMGGDDDTKTSVETQWWAEMNNSWSQTMNEHTNFDVFIINGSGHCSSGLYFANQQPDFEKWVSNIVASASLIYVQQETVVMNTSVTMTAATDPTSTTTEAYESRPVESPVSPMNNTFPSSGSETDTPSAATCKATAGHILIATFLCLQLCLLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YC42</accession>
    <name>A0AAD8YC42_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006329</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YC42"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="324" mass="37100" checksum="C5640B6C0C9D7308" modified="2024-05-29" version="1">MYVEHIEQSPSPMATRMRWGNAQEATSVLTALNYFCGLDEDTVIREVGMCGAGFDPDVDNSDTNVRDGALLQGLSIGATPDALVCHSDGTWKYSRLRIIAHLFGIRFLLIIPATKAVVGRNRNRNKKKKKLHSNRRRRHQNSRKLNDDIADDYGDGEPAKKFAPKHYLIRDFHLERRIPPVYIPQLMMEILCVGNAVDLDGNAQSSSSSEPLCKSAVMVRQTATKGAIMLRLNRDEEWITEMQYFLGRFKKEYVDTGIIPEDNFFWESGGERYHKFLERTKELSESVEFVAFIDHQKIQRVVFEHSVKGEIDLFLDEVDVEEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YC47</accession>
    <name>A0AAD8YC47_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YC47"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="317" mass="34472" checksum="56A1642E36A8912C" modified="2024-05-29" version="1">MFAPITSSHNFYTTLYDIMTFQNAKSKSKYVALSLALAASPSSYALASSNVIVEKKPDEGLRGVGQRELKVKTCSKEKRVQVYRFCIEGDCDAGAEGEHRLKLDGQWLWGGFRDFREGQCHSINHSAKTVAAWKSLAVGTEEHDDWSENDSWFATMTASDWYSETCETYEVILSKQHAAEKKESMCWEMSAAGGAKGVDLGLTATRCSEWTKPSESFLWYLKVEPKDILTDSPTPLPTPPPTLATPSPTDAPSLPPTEASGAPSDFPSLPPTDVPPPTANVSIETSLLGTSASYHATFNAKFVSLVIGLLGALVYLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCB2</accession>
    <name>A0AAD8YCB2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Vacuolar ER assembly factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_006434</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCB2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070072">
        <property type="term" value="P:vacuolar proton-transporting V-type ATPase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021013">
        <property type="entry name" value="ATPase_Vma12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31394">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31394:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11712">
        <property type="entry name" value="Vma12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="25"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="40"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1742837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="294" mass="32046" checksum="8ECAEFA8339035AC" modified="2024-05-29" version="1">MGNLRGIQITPALRAAIKAVLALPQAEVSSEPKGDGNKKSSTSLPPSPSPSLSLARASNAKEQLSSLMTVKESTSLLQTALNNAAVDAALPLAGVLALQSLIQSSSTDPKTKTQQSQDLEAALQHTKQLSFQKSPPNKSSNKQSNDLKFQKRLERLRLQDEERSYSNLTTNLKTAASLKDDNITVKSMTYAASVGLNMIVAPISFGVFMYFFAGSIFNRLFGMEGPASGDIDIKRVIAGVVSGVFMLFVEMILFVIRSHELDASVRKKSKRKENRANPFGYTQKSMERVYVRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCG9</accession>
    <name>A0AAD8YCG9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DUF3506 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_005904</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCG9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045048">
        <property type="entry name" value="FBXO31/39"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10706">
        <property type="entry name" value="F-BOX FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10706:SF130">
        <property type="entry name" value="F-BOX ONLY PROTEIN 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12014">
        <property type="entry name" value="Cyclin_D1_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="59"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="119"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1743283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="381" mass="43265" checksum="C98AED604F8564BA" modified="2024-05-29" version="1">MLGLLSSAIMRFIAPLLAVSSMGILVCGFNAFPTKHLTHHVPLSVSRSSLFMSTSFGSFPEEWSDSDNSESTGRYSTNQYDGNDGAFPLPDDTDITEARQLRWEREAMVQSKFVSDDGVFELRRKISDLRLRLMDAREKLAEEGQQQRIRELEEQLFSLNTKDAEFMYAMSLELMENAQREGDPHTAEKYRLQAAEARLVIPQLNMHGLWVGKYGDHGFEMINVTYAGDTLVATKVTGDQNVPKGEVSFTVDLSPHIHSDKGMLSLEPIELNAKASRQWGKKFLPRYQGQGQVAAEGFTNGKWIEGQLILVGRFFSFAWVPIGHQVFFGRPSSDLTLKMLREQQEDDLKRDQVSVMREAAHNMMEETYWIEKDDSFQGGWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YCR0</accession>
    <name>A0AAD8YCR0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="5">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_006659</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1743062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YCR0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF565">
        <property type="entry name" value="AT28366P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0464">Manganese</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="12">
        <location>
            <begin position="41"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="213"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="407"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="542"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="666"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="266"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="294"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="416"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="552"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="669"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1743062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="696" mass="75167" checksum="F0CD450BAA3BBC00" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD44</accession>
    <name>A0AAD8YD44_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">PHD finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_005635</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD44"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05162">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059153">
        <property type="entry name" value="NSD_PHD-1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24102">
        <property type="entry name" value="PHD FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24102:SF28">
        <property type="entry name" value="PHD-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23011">
        <property type="entry name" value="PHD-1st_NSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="365"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="680"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="177"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="273"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="328"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="649"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="901"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="96"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="927"/>
            <end position="936"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1744038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="981" mass="108671" checksum="333CBA7E4163872A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDB1</accession>
    <name>A0AAD8YDB1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004914</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDB1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="315" mass="33721" checksum="62398A9E04848F77" modified="2024-05-29" version="1">MLFSLLRDYQPVDSITQILAADDDAKIDAICMLDPGTGYLPPSYGVPNNHPHWGQVISWIIGQRRGKVVETGRILKLDLIDGGSGYVETPEVQISAPPGDGTNKKVQATAKAVLGKGKNKGVIEKIEIVNPGLGYNAIDEVTVTITPPDKGWTAASAKAILEYQVARIDIVHEGRGYAAEKPINVDIDPPPGVDASGDIARRAFAVAYPKGKTTSYASFISNNVVKASSSSVDTSAWIAGPTSSQLLSLMPSGFGLQFDEKLEKYILTTPSSSNTWEDIITGSLEGRTSNQSIQYLAFGEGVPSSLKSPWICHLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDF3</accession>
    <name>A0AAD8YDF3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sel1-like repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_006043</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDF3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1743422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="209" mass="23896" checksum="C1FB3842964ED11E" modified="2024-05-29" version="1">MMTCCSKTVCKGCDHANNLREVTMMLKSTCPFCREPTPSTDEQCDKQMMERIAVNDPVAMRLWGREQYKKGNYQSAFEYYTKAAELGDVDAHFRLAFLYHHEHGVEKDYGKFVHHLEEAAIGGHPGTRCRLGYIERISDRTERAVKHFIIAATQGDDYSIKLLMDVFKNGMVKKEDLAAALRAHQAAVDATKSPQREVAEEFYRNRPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YE04</accession>
    <name>A0AAD8YE04_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_004985</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YE04"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48038">
        <property type="entry name" value="RIBONUCLEOPROTEIN RB97D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48038:SF1">
        <property type="entry name" value="RIBONUCLEOPROTEIN RB97D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="602"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="718"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="256"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="342"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="573"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="670"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="256"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="573"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1744452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="808" mass="86347" checksum="7C54C1BD3463CC43" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEU0</accession>
    <name>A0AAD8YEU0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">glutathione gamma-glutamylcysteinyltransferase</fullName>
            <ecNumber evidence="1">2.3.2.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_004660</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.15" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEU0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016756">
        <property type="term" value="F:glutathione gamma-glutamylcysteinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046938">
        <property type="term" value="P:phytochelatin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010038">
        <property type="term" value="P:response to metal ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.30">
        <property type="entry name" value="Phytochelatin synthase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040409">
        <property type="entry name" value="PCS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007719">
        <property type="entry name" value="PCS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038156">
        <property type="entry name" value="PCS_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33447">
        <property type="entry name" value="GLUTATHIONE GAMMA-GLUTAMYLCYSTEINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05023">
        <property type="entry name" value="Phytochelatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51443">
        <property type="entry name" value="PCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0104">Cadmium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Peptidase C83" evidence="5">
        <location>
            <begin position="121"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1744127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="408" mass="45175" checksum="37419077837C6EF0" modified="2024-05-29" version="1">MRGAVRLFVPGRGSHKRIRVTVSADFLPSVTSSCLQLSSMRTTCSSGQHSFICGSIQSHNPHNRHNYFNTLSYSSAASTDDAHSSQRDAECINHNDTNNNSCHLSEPLVKPGTPLPPPLPNPNYSFRGRALPTNLIAFNSTEGKQRFMQALQNDCAESYFPLSQQFLNQMDPAYCGITTLVLILNALAIDPNVRWRGGWRWYGDEQICQGVDVKKKRPLRDRGEQRNVAGSSLDAHDIHEFRNDIRNAVRMPPKTQQETDLEIATHADAHNDSQARACNGGYFLVTSFGRSSLSQTGDGHFSPIAAYHEPSDSCLVLDVARFKYAPYWVTVKDLYDAMIPEDKATGQSRGWLLMYPPTKGKHGSKKSLTVEEIEGKRPAACVPLAGSGVSLCAVEKIKVDYCSVNNNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YEV1</accession>
    <name>A0AAD8YEV1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RuvB-like helicase</fullName>
            <ecNumber evidence="8">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_004807</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the RuvB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YEV1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000010">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.360:FF:000001">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.360">
        <property type="entry name" value="RuvB-like helicase, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027238">
        <property type="entry name" value="RuvB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041048">
        <property type="entry name" value="RuvB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042487">
        <property type="entry name" value="RuvBL1/2_DNA/RNA_bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010339">
        <property type="entry name" value="TIP49_P-loop"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11093">
        <property type="entry name" value="RUVB-RELATED REPTIN AND PONTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06068">
        <property type="entry name" value="TIP49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17856">
        <property type="entry name" value="TIP49_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="10">
        <location>
            <begin position="63"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1744274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="455" mass="49560" checksum="79FB4D874728E67B" modified="2024-05-29" version="1">MKIEEVQSTTKTTRVSAHTHIKGLGLDPHTGVANPIGSGLVGQEQAREACGLIVDLIRSRKMAGRALLLAGAPGTGKTALALGVAQELGPKVPFCPMVGSEVFSSEVKKTEILMEHFRRAIGIRIRESKEVYEGEVTELTVEETEDPLGGYGRSISHVIITLKSTKGSKTLKLDPSIHDGLSKEGITVGDVMYIESNSGAVKRVGRSDAYAAEFDLEAEEYVPLPKGDVHKKKEVVQDVTLHDLDVANARPQGGKDVLSLMSAMGKAKKTEITEKLRTEINRVVNRYIDQGVAELVPGVLFIDEVHMLDIECFTYLNRSLESTLSPIVVFATNRGVCQIRGTDVLAPHGIPIDLLDRMLIIRTLPYSSDEMVQILSLRANVEGIEIEESALRLLSDIGSRTSLRYAVQMLTPARIVAETVGRTAITDEDVKDIDELFLDGKASGQMLAKTEGYMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFH1</accession>
    <name>A0AAD8YFH1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004194</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFH1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="98" mass="10503" checksum="837C2A01D1D6ECC1" modified="2024-05-29" version="1">MCEKECERFGNIGAYRGFEFSVGKRCTCLFDVDQAPPVPDSGEAPDYVGGSDGGDGDVFSTTSMPGTTCFASREVGSKSKQLLPFFLPLLSLCCSRNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YG21</accession>
    <name>A0AAD8YG21_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YG21"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1744790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="314" mass="33263" checksum="8C7ACE615E2B7A35" modified="2024-05-29" version="1">MSPQFRATTPNTTSTLANGDGEPCNSCSVALSVAELAKAADMSFALHKIERDSSAEWTPLNPLLSQDSSCAQAYSRKRSCNQISSQDPNQPFLSSYGSAFLSGIFADIAQASDEKPGASNPKSDEPHNKKIRTMPSALTLGRPSKSFKALAGLTDGADNVAPSVETPLVPFVVSPRSNQSTANIHHFKDQVRELQGMAFPSLPQIPNTISSSSFSSSNLTAPSLSRDVSQASISSDMDQDSSDSDFGWFVSTDDDADSALIKERAMSVSTAPAFDDLAFKARPAVGAVAEPPQDTEVQQALAADTIDDVLGDFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YG79</accession>
    <name>A0AAD8YG79_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">GPI ethanolamine phosphate transferase 3</fullName>
            <ecNumber evidence="12">2.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_003850</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.-.-.-" evidence="12"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YG79"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051377">
        <property type="term" value="F:mannose-ethanolamine phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16023">
        <property type="entry name" value="GPI_EPT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037675">
        <property type="entry name" value="PIG-O_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039524">
        <property type="entry name" value="PIGO/GPI13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23071:SF1">
        <property type="entry name" value="GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23071">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL GLYCAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="535"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="594"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="624"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="648"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="688"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="791"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="879"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="947"/>
            <end position="973"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1745926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="996" mass="112193" checksum="BA9BD4495378BE24" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YH96</accession>
    <name>A0AAD8YH96_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003428</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YH96"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="12"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="159" mass="17977" checksum="014D1BC47F26F583" modified="2024-05-29" version="1">MFLTKRVAVNDPLAFQQMGVRYYEEGDYDTAFGYFTKAAELDRCEKNEEKEKIHSEEAAIAGHPIARYNLAIIEGCIGREKREMSYLNRSVKHFIIAANLGCNDSIQQLKHYYSAGWVSTEDFAAALRANQAAVDATKSPQREVGLREVASSQDGYRRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHD1</accession>
    <name>A0AAD8YHD1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002739</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHD1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="139" mass="14640" checksum="D3ACF64AA8F542B7" modified="2024-05-29" version="1">MSSLSSASPSLAFVSVPPGAAAAAVAWKVSSRQPRFFFSTPLNSFAESEPEDSSETSSDGKLPSISPQNSNNASNTQPTVATPAPNMGASIDAQNVGEMLFNEQLLKSGRGDVRVGPMRRWKDFRGNEIVPDNAVDGPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIC8</accession>
    <name>A0AAD8YIC8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Glucose-6-phosphate isomerase</fullName>
            <ecNumber evidence="3 8">5.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_003761</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11816"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="EC" id="5.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the GPI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.9" evidence="3 8"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIC8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048029">
        <property type="term" value="F:monosaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051156">
        <property type="term" value="P:glucose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05015">
        <property type="entry name" value="SIS_PGI_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05016">
        <property type="entry name" value="SIS_PGI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1390.10:FF:000001">
        <property type="entry name" value="Glucose-6-phosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10490:FF:000004">
        <property type="entry name" value="Glucose-6-phosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00473">
        <property type="entry name" value="G6P_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023096">
        <property type="entry name" value="G6P_Isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018189">
        <property type="entry name" value="Phosphoglucose_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035476">
        <property type="entry name" value="SIS_PGI_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035482">
        <property type="entry name" value="SIS_PGI_2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001211">
        <property type="entry name" value="PRK00179.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469:SF1">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00342">
        <property type="entry name" value="PGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00662">
        <property type="entry name" value="G6PISOMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SIS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00765">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00174">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="5 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6 8 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1745837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="554" mass="61367" checksum="19EB4FCBAB1DA6ED" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJW1</accession>
    <name>A0AAD8YJW1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_002054</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJW1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861:SF3">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14390)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861">
        <property type="entry name" value="TRANS-ACONITATE 2-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="63"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="262" mass="29373" checksum="E45F4CE7CDAC3368" modified="2024-05-29" version="1">MEIKGKDSSAHTTLLKANQDHFDEQATKWDDDPEYVKVSRTSYATIMHHLGRFLSSRDDDHPPTNILNFGCGTGLLEDQLRYNVTSITGIDISDGMILRMNTKIQAESWMNVTALQMDILDEAQASLLPVQGFDMIISCYTFHHLQDVTAVGGALLKYLKPGGYLCIIDFAAASTENNDVHYHHTQHDHQQEQDEQQQTLGMKLSEAAKASIGSHDGFSKRFLIDYYQSVLDLQNVTVEDATPLNCDGIEYPTVIAYGQKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YK41</accession>
    <name>A0AAD8YK41_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ADP,ATP carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_002022</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ADP/ATP translocase tlc family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1748059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YK41"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005471">
        <property type="term" value="F:ATP:ADP antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004667">
        <property type="entry name" value="ADP_ATP_car_bac_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31187">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31187:SF1">
        <property type="entry name" value="ADP,ATP CARRIER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03219">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="337"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="369"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="477"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="240"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="263"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1748059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="514" mass="55532" checksum="E7ACFB3144A66221" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YK48</accession>
    <name>A0AAD8YK48_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">monogalactosyldiacylglycerol synthase</fullName>
            <ecNumber evidence="2">2.4.1.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_002333</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Plastid</location>
            <location evidence="5">Chloroplast membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.46" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YK48"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031969">
        <property type="term" value="C:chloroplast membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046509">
        <property type="term" value="F:1,2-diacylglycerol 3-beta-galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009695">
        <property type="entry name" value="Diacylglyc_glucosyltr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050519">
        <property type="entry name" value="Glycosyltransf_28_UgtP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43025">
        <property type="entry name" value="MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43025:SF3">
        <property type="entry name" value="MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06925">
        <property type="entry name" value="MGDG_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Diacylglycerol glucosyltransferase N-terminal" evidence="8">
        <location>
            <begin position="54"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 28 C-terminal" evidence="7">
        <location>
            <begin position="372"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00046299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF06925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1746989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="494" mass="54519" checksum="2E7B40F8E28A5E50" modified="2024-05-29" version="1">MMAQRKQLEMEIERSSEQHPQDEQNNNDDDMSTTPTKKGPLKILFLSSDTGGGHRASAEALANQFQRLYPGTTYDLLDIWSDIDSSWPYNSIKDAYKSMSASPWKWRTLYHVSNTAVYAKFADFHSYYMNEGMIREKIEQYNPDVVVSVHPTMNYIPLFSIRKVAEKFDKEIPFFTVVTDFGSGHCTWFNKDVDRMYLASEPIKAIAQKRGGVPDEKIVMSGLPIRYDFAAQADAMGDRTTDEGKAHQQKIREELNIDPNKKIILVMGGGEGVGSLSSIVNELYAKLRTQGVDATICVVCGRNEQLKGDLETRCWDTVVSQSLNSYASLKSRVVTKLLSAHASRSRRIQAALDRAAAKAAKGRDVAEVPGNVDVIPLGFVKNMAEYMVAADVLVSKAGPGTIAEAAAVGLPIMVTSHLPGQEAGNVDIVLDGGFGDYCEDPETIALEIACWLQDSQLLDVMSKKAQAVGHPHAAEEIAQDIGDTTHDLMEKNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKL4</accession>
    <name>A0AAD8YKL4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF760 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKL4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008479">
        <property type="entry name" value="DUF760"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33598">
        <property type="entry name" value="OS02G0833400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33598:SF4">
        <property type="entry name" value="OS02G0833400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05542">
        <property type="entry name" value="DUF760"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="231"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="382" mass="41123" checksum="BD932A21155CFE34" modified="2024-05-29" version="1">MSRKETENLRRAREQIAEGRLPISYGAMNMDDNSDANKAENESTDSSGMGQFGPLSTENNNNTAGDAIDVPSSSSSSSLARGKQNPYLNVVSRLSPSDLIARFTATASPRVQDAVRTTILGLIGGLPTMAFETKTVATGERLASLMFQLQMTGYMFANAEYRASLSQSLGSSNTLMLNGESSQDGKAWLDGKRIDGKIKVRYGASAGANSESSIDDESESPSPSTFGMEVEVDAEAYMAELRGEVSRLREELDATKQAKEEEIRKDLLAYIRTLPKQELSQLTGTMSPEVLEAMKGLVTAVLAGIGGNELEELADLDDGSKIGPNTVTEQSGEALAQLCMWQLVVGFNLRELEVREEFRASMKMIGSTSNNAEEAGGSSDFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLN5</accession>
    <name>A0AAD8YLN5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_001463</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLN5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052592">
        <property type="entry name" value="LRR-RLK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48054:SF47">
        <property type="entry name" value="OS06G0179800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48054">
        <property type="entry name" value="RECEPTOR KINASE-LIKE PROTEIN XA21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="126" mass="13777" checksum="86A411B77F18C80F" modified="2024-05-29" version="1">MKREPKYFLGAGACEEGFVTRLDLWGNHLTGALPPEIGSLNSLTSISVFDNNMRGPPPKSMVHLKKLQKLYLQKNEFQGDVDFLCGNEMDLFKTDCGKKGGVTCSVVQGVDIMQTTTSPLASVVTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YNV4</accession>
    <name>A0AAD8YNV4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="6">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_000626</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="6">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YNV4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025313">
        <property type="entry name" value="SPB4-like_CTE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13959">
        <property type="entry name" value="CTE_SPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01178">
        <property type="entry name" value="DUF4217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="210"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="368"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="557"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="173"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="378"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="388"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="557"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1748687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="601" mass="67092" checksum="69949B17B174FC5A" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4L7</accession>
    <name>A0AAD9D4L7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4442 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015368</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4L7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027961">
        <property type="entry name" value="DUF4442"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14539">
        <property type="entry name" value="DUF4442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="171" mass="18953" checksum="BEDB0E5B4E9FA33F" modified="2024-05-29" version="1">MGGSYKLNKMATSIAKLQSIVPNSFQPMALSYVFNSMVKLAGTAGIRIESLTHTNARVSLQNKKKIQNHIGGLHACSMALAAESATGILIGMNVRDTHLPLIKSMKVDFVRRCEGNINVEASITEDDYKRIHEEEKGEVLVKCTVIDESGKEPIKADMLWAWIPKQRRSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D4Y5</accession>
    <name>A0AAD9D4Y5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016203</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000054">
        <property type="protein sequence ID" value="KAK1733065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D4Y5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="200"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="321"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="457" mass="48425" checksum="B5BCDDFD099EBF00" modified="2024-05-29" version="1">MTSSTNNNTATTSCQIVLTLAHLLQQHSLSYDSDKNSLLHTSVRCASHLANTTTGGGEVHIVLTGSPRPTFAETNAWLLEGSSNSAAAAGNNHSNSSSGGADNNDIAMTETDDTNDRPAHLKGSYSIADNVHHSSSNIYNQEEEERMMQDDENTTKSELQDYITEFTDSKDGGNGVSTAAVSNSKRGITGGGGHNTSFIRRNTTGVTTTTNNTNNNADDSTTTTTNRRRSTIDAAESSSSSVTNNTGPMVGQAVVNAISQSSGVGLQSSRSKLLQGTIDRPLWSQNRWTDGECLFSELVELCGMERFEMVGGAAHKKRLQKQQQQKQQGGPDDAAGGAGAPSLAVVASPPPATAATNMSANLITVPATTLREPNAGVSQTTMDEIARGVLRTVKRKKSPPASKVYIVVPGVNQGVSEEQRGVVVTSLKQAWEKLEQYNHMIGQPNLISGAELEFVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5A8</accession>
    <name>A0AAD9D5A8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015817</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000048">
        <property type="protein sequence ID" value="KAK1733529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5A8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="89" mass="10395" checksum="4BEE023496F058E6" modified="2024-05-29" version="1">MTSAASARSCWEQSPFDDVNEEEFDEDDFLMEYEINSEDPALEGVDTAAVTPIIKDTLVRKQRDELMKQRSWKKFCRYFDPASSRIYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5E8</accession>
    <name>A0AAD9D5E8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nucleotide-diphospho-sugar transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015733</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000047">
        <property type="protein sequence ID" value="KAK1733560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5E8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005069">
        <property type="entry name" value="Nucl-diP-sugar_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03407">
        <property type="entry name" value="Nucleotid_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleotide-diphospho-sugar transferase" evidence="2">
        <location>
            <begin position="213"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="787" mass="88271" checksum="65DF8C77514A39C9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5S9</accession>
    <name>A0AAD9D5S9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">1,3-beta-glucan synthase</fullName>
            <ecNumber evidence="3">2.4.1.34</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_015223</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>[(1-&gt;3)-beta-D-glucosyl](n) + UDP-alpha-D-glucose = [(1-&gt;3)-beta-D-glucosyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21476"/>
            <dbReference type="Rhea" id="RHEA-COMP:11146"/>
            <dbReference type="Rhea" id="RHEA-COMP:14303"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37671"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.34"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.34" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1733965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000148">
        <property type="term" value="C:1,3-beta-D-glucan synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003843">
        <property type="term" value="F:1,3-beta-D-glucan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006075">
        <property type="term" value="P:(1-&gt;3)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026899">
        <property type="entry name" value="FKS1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003440">
        <property type="entry name" value="Glyco_trans_48_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12741:SF48">
        <property type="entry name" value="1,3-BETA-GLUCAN SYNTHASE COMPONENT FKS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12741">
        <property type="entry name" value="LYST-INTERACTING PROTEIN LIP5 DOPAMINE RESPONSIVE PROTEIN DRG-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14288">
        <property type="entry name" value="FKS1_dom1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02364">
        <property type="entry name" value="Glucan_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01205">
        <property type="entry name" value="FKS1_dom1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="148"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="554"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="588"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="622"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="665"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="730"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1633"/>
            <end position="1656"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1668"/>
            <end position="1688"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1758"/>
            <end position="1779"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1791"/>
            <end position="1807"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1891"/>
            <end position="1914"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1926"/>
            <end position="1943"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1949"/>
            <end position="1970"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1977"/>
            <end position="1999"/>
        </location>
    </feature>
    <feature type="domain" description="1,3-beta-glucan synthase component FKS1-like" evidence="12">
        <location>
            <begin position="405"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="866"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1064"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="2140"/>
            <end position="2169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="1064"/>
            <end position="1078"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1733965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2169" mass="242953" checksum="609998E3869B3DDB" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6K2</accession>
    <name>A0AAD9D6K2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alpha-dioxygenase 1</fullName>
            <ecNumber evidence="8">1.13.11.92</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_014648</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.92" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6K2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102672">
        <property type="term" value="F:fatty acid alpha-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050783">
        <property type="entry name" value="Oxylipin_biosynth_metab"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903:SF11">
        <property type="entry name" value="ALPHA-DIOXYGENASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903">
        <property type="entry name" value="PROSTAGLANDIN G/H SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0611">Plant defense</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="396"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR619791-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1734775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="681" mass="77624" checksum="AFD7FD2C3D009733" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D6X2</accession>
    <name>A0AAD9D6X2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glycerophosphodiester phosphodiesterase</fullName>
            <ecNumber evidence="2">3.1.4.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_013333</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a sn-glycero-3-phosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12969"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:83408"/>
            <dbReference type="EC" id="3.1.4.46"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycerophosphoryl diester phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.46" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D6X2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008889">
        <property type="term" value="F:glycerophosphodiester phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43620:SF7">
        <property type="entry name" value="GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE GDPD5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43620">
        <property type="entry name" value="GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="GP-PDE" evidence="8">
        <location>
            <begin position="160"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1736197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="501" mass="56652" checksum="A1FAF97C6D74B241" modified="2024-05-29" version="1">MKESYQSMGVAGDAKMSDGIINCKSSSYHSISETDTDVNKIAAKDIPSHQSAHRKRCCKKHKSFLSGIILGAFLVCSRTLYEDVRLMMTIIHSSSTNHRTHNPKLHTLNTLLHLHSHNQTIVSIGPRPYFLINEMDNSNPELKRTLQKCALNIKSFRPSDFVLGHRGAALQFPEHTDRSHDAATRMGAGVVECDINLTKDKQLICRHEMCDLHLTTNVLMTPLASKCTKQFRPAIGNLPATAKCCTTDFTLSEIQTQMCGKMSSSNKHAKTPQQYISHTKSFQTELYAHDCPHIQSHKNFIDVVNANGGSFSPEYKMLDYKFTKQYTRQMFLQQVLHDYNSTDPSRVYFQGFEWEDLYYVAKNQFGLNTFALDKNWIALTYTRHQLLNYFHPLVDHGVTAIAPSISMLLEVDTENNLVPTLYAKVARELGLGIVAWTLERSDALSKGGGWYYSTISQVLRTDSDVIKVLDVLYEDVGIMAIWTDWPSVATFYANCKGISLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D784</accession>
    <name>A0AAD9D784_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translation initiation factor IF-1, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_013643</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IF-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D784"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04451">
        <property type="entry name" value="S1_IF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000002">
        <property type="entry name" value="Translation initiation factor IF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00075">
        <property type="entry name" value="IF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004368">
        <property type="entry name" value="TIF_IF1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00008">
        <property type="entry name" value="infA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33370">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33370:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50832">
        <property type="entry name" value="S1_IF1_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 10" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041972110" description="Translation initiation factor IF-1, chloroplastic" evidence="8">
        <location>
            <begin position="23"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="S1-like" evidence="9">
        <location>
            <begin position="73"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00068272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1735480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="152" mass="16495" checksum="A4214BF649F71715" modified="2024-05-29" version="1">MMKLILVLLSAMLCMSSTSVNAFAPSFPTAPVRSATLQFTTPSAPISTSATSTTLFGKKAARALGNARKGKSERVKKVKDDVIEVEATVIESLPNAMFRCTIDGAPETQEPVLATISGKIRKFFVKILVGDKVTIELSPYDLTRGRITFRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7E3</accession>
    <name>A0AAD9D7E3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013792</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000033">
        <property type="protein sequence ID" value="KAK1735629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7E3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="427" mass="48527" checksum="344E45C313B73233" modified="2024-05-29" version="1">MNTRTTPEPKSLKQQQQQPLLFPPSSSVTPSPHPHQKGPLPSPFEHKHHLPSITVTVLPPPSETKYTSEEEKKEKTRQYNKAHREKLKQDGKFEKHKERVRVYNAKRRQTLNIMAKEYGLSVRKMEQTLKETKKNTGVDLLSIAINGDQTKDEHKEEAADEARNNNNNKSIAKTPQQQVDNAVTTSNDIPAAQTYLAQRCSQTPQPSSSLRPLPSQTSLQNEEKKDLTKASAAIVVAAENQVITPSTTPPPSRNDAAPTATHTDNPEKQKKNKHNQHNRAYRDKLKQDKRRYEEHKEKARQYNEKRRKKLRAMAKETGLTMKEMEKTIREAKIISALTVTASKEAEKLRPVPTRHLIRVPPLQLEAATTNCLDILSDAASIVLSQSDHHHHQQQHQHTNTFTPLSPRRQHRTVSEDNCDASMEVNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7T3</accession>
    <name>A0AAD9D7T3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7T3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="176" mass="20278" checksum="7EDEAC3535176EC3" modified="2024-05-29" version="1">MAERQPLHQPLLPVSALVHEESPPKKHLCCFCCCNMRETVLWIQFFFGIVWATAWLISYSLGYYKQWASDPQIIADLTLAYWKVSIINGVGIGVAVVVIFGAIYYKPALVFLGAIYTIIEAILTPIYMYPVVKDFYTSSWMYIVWPIIYGMLIVYPHVVFTYELKTGVWENPNFSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8N0</accession>
    <name>A0AAD9D8N0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Bromodomain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_012334</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000027">
        <property type="protein sequence ID" value="KAK1736889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8N0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027353">
        <property type="entry name" value="NET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038336">
        <property type="entry name" value="NET_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45926">
        <property type="entry name" value="OSJNBA0053K19.4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17035">
        <property type="entry name" value="BET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51525">
        <property type="entry name" value="NET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Bromo" evidence="5">
        <location>
            <begin position="19"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="NET" evidence="6">
        <location>
            <begin position="127"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1736889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="225" mass="24510" checksum="76CCDEA239248311" modified="2024-05-29" version="1">MSSSAPEWQAMSKLVSQVYAKADAEPFREPVDWKALGLFDYPQVIKKPMDLGLIKKKLHENKYKSIHDAADDVRLIWKNCMTYNADGSDFYNLAQTMAKKFEEKFEKLCAQNEVAAAAGGGDGGAAASGGSGVAEEPTIEEKRAFAKSLYKIGKDDLGKVIMDLDVKCPKSLIKNSAEDEVEINVDLISPAAFAEVREFVNEKVAEAGGAAGGKKKKTAKRARNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D8Z2</accession>
    <name>A0AAD9D8Z2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">C-terminal processing peptidase</fullName>
            <ecNumber evidence="9">3.4.21.102</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_012071</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S41A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.102" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D8Z2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06782">
        <property type="entry name" value="cpPDZ_CPP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07560">
        <property type="entry name" value="Peptidase_S41_CPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.42.10:FF:000369">
        <property type="entry name" value="WD domain, G-beta repeat, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.44">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004447">
        <property type="entry name" value="Peptidase_S41A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32060:SF22">
        <property type="entry name" value="CARBOXYL-TERMINAL-PROCESSING PEPTIDASE 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32060">
        <property type="entry name" value="TAIL-SPECIFIC PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042015722" evidence="6">
        <location>
            <begin position="43"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="7">
        <location>
            <begin position="254"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Tail specific protease" evidence="8">
        <location>
            <begin position="404"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="283"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="289"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1737204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="864" mass="94794" checksum="DC506E72F0228014" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D914</accession>
    <name>A0AAD9D914_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sel1 repeat family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010582</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D914"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF147">
        <property type="entry name" value="SEL1L ADAPTOR SUBUNIT OF ERAD E3 UBIQUITIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="138" mass="15461" checksum="E5C14A979C5DDE41" modified="2024-05-29" version="1">MRDPRCPFCREPYITSSAEADRNLLKRIEAGDRVAFRQKGCQGKEEHNYSVAVEYLTKAANMDDLYYNGEGVESDMKKAVHHLEEAAIGGHPRARFNLGVVSTRDGKSSRAVKHYIIAASQGNDDGLEQLKELYKKGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9L6</accession>
    <name>A0AAD9D9L6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ATP synthase subunit epsilon, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ATPase epsilon family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9L6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042776">
        <property type="term" value="P:proton motive force-driven mitochondrial ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12153">
        <property type="entry name" value="F1-ATPase_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1620.20">
        <property type="entry name" value="ATP synthase, F1 complex, epsilon subunit superfamily, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006721">
        <property type="entry name" value="ATP_synth_F1_esu_mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036742">
        <property type="entry name" value="ATP_synth_F1_esu_sf_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12448">
        <property type="entry name" value="ATP SYNTHASE EPSILON CHAIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12448:SF0">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT EPSILON, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04627">
        <property type="entry name" value="ATP-synt_Eps"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48690">
        <property type="entry name" value="Epsilon subunit of mitochondrial F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="70" mass="7570" checksum="E359141F5A67F558" modified="2024-05-29" version="1">MTVPTTFWRLAGVSYVQYVTKASSTLRAALKEPAKSKALAQETFSYNKSVWSNGEQGAKKLTDSLAAVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9X3</accession>
    <name>A0AAD9D9X3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Methyltransferase</fullName>
            <ecNumber evidence="6">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_011354</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ANT/ATPSC lysine N-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9X3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905706">
        <property type="term" value="P:regulation of mitochondrial ATP synthesis coupled proton transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026170">
        <property type="entry name" value="FAM173A/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13610">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13610:SF20">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="151"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="259"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="11"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1738060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="498" mass="56255" checksum="FC9D78A6CEBDBA95" modified="2024-05-29" version="1">MVLMRPKSSFPYKNQSMSSTTNSGNKPEAQTMSQEETPFGLQKQQGTSNRLAPYNPTHATAREKALDLLGLSDNDVLFDLGCGDGRLLFTAMERFYDDDYLMQQHQKIFNSVVTTTHQPQHESAASTDNIIDNGHDGKEVKFNDETKKIRQSLDSSQPPIPHMMCNASDDEEEESNDVSFDTPSKMLSVAFNRSFNTPQKSAVSAMMSPLMTPHALPMPTTPTTSNRKSHKYDFPTLHLSPIKNEAIAEIQDIPLTITASSSIEEPNQEESETSPRNRKWSLTLSDTRTLSSTSSQTVGLRCVGIEYDQALVEAANNQIDSFKMYESFDDGDWVKKRLCIRWGCVFDEWNFPDVHGSIDGKMEQQLAQHLSLLEDATAVFVYLLPEGLKKVKPLLQEAARRREQMEQQQEELLQQTHRKDYSHVSDITDYDFLRTTQGSVAATEKRTLSISPVFRVVSYMFSIPGWTPTKVDRSSKGGCPLYLYENVTELCDEHELTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DA42</accession>
    <name>A0AAD9DA42_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010924</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DA42"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041938032" evidence="1">
        <location>
            <begin position="20"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="298" mass="33079" checksum="D114B9684582522E" modified="2024-05-29" version="1">MAAYGLLLLITMLISSISAFSIKIVGLPGGKVESLPGMYVNSFRRWIAEEEEQSNNNDDNGEMNSCASNTIKIEPIAGAGISIDEGWVNPTSTADLFWPLDVKLQARPALNVMFKQGVLSYASPGLDVRVPHNDGSWRNYGMNSQPIARQWTSLEIAMEQMFHIESFILHKESTADDIKHTTLFDSMDIKNSMQKVATFIGEIDPLSPLNSGFHIVSFPLIDRFSDLPCPELTEDENEEIYKIVMLGTSEPFGSKLLDMDEDILTMSSTSALEVVVARTVKGKDSEYLPEPYKPLYIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAA0</accession>
    <name>A0AAD9DAA0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_009691</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAA0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="419"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="482"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1739932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="528" mass="57024" checksum="803A31922B8EDD04" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAR9</accession>
    <name>A0AAD9DAR9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008686</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAR9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="374" mass="40634" checksum="2DB89AF3485C90D2" modified="2024-05-29" version="1">MPSGSSSVATDATKKKKKKKNVIKSIAKGMSFKKKKKFVDDDTVVGVAVEPKGAGSNKAASTRPAASPAAKPIQVVLLLMDPNSRRFELLQLEFDSNKALVSDVVRQVQSSATEDTLRNLSYGGVCDQDGTEMIQSLKLSNFCMGNEIVMAIPKGMNGKATLQLAQPILSDPKVADMLRPCGVKIKRISKPEKKMEKIAEEDSNETKKVTPPPTPKQPVVSKSRSTSKTPTIFGIGIMTLLFFTILRHIRVTKKIESGDVLLPGQWKSQCGIWDVLPEKLSEKYCNTKSSSTLEMGRDGTLRYFTKSGEDGEKSESWILSGNSAAQCAESECVNSDDADSSSATFVSDGGSWYVDLDDKRTALGKDVVQDFMSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DB31</accession>
    <name>A0AAD9DB31_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA-5-taurinomethyluridine 2-sulfurtransferase</fullName>
            <ecNumber evidence="3">2.8.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">QTG54_009786</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>5-taurinomethyluridine(34) in tRNA + S-sulfanyl-L-cysteinyl-[protein] + AH2 + ATP = 5-taurinomethyl-2-thiouridine(34) in tRNA + L-cysteinyl-[protein] + A + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:47040"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11726"/>
            <dbReference type="Rhea" id="RHEA-COMP:11732"/>
            <dbReference type="Rhea" id="RHEA-COMP:11733"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:87171"/>
            <dbReference type="ChEBI" id="CHEBI:87172"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.8.1.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MnmA/TRMU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.14" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000018">
        <property type="protein sequence ID" value="KAK1739243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DB31"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061708">
        <property type="term" value="F:tRNA-5-taurinomethyluridine 2-sulfurtransferase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002143">
        <property type="term" value="P:tRNA wobble position uridine thiolation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01998">
        <property type="entry name" value="MnmA_TRMU-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.280">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004506">
        <property type="entry name" value="MnmA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046885">
        <property type="entry name" value="MnmA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046884">
        <property type="entry name" value="MnmA-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023382">
        <property type="entry name" value="MnmA-like_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11933:SF5">
        <property type="entry name" value="MITOCHONDRIAL TRNA-SPECIFIC 2-THIOURIDYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11933">
        <property type="entry name" value="TRNA 5-METHYLAMINOMETHYL-2-THIOURIDYLATE -METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03054">
        <property type="entry name" value="tRNA_Me_trans"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20258">
        <property type="entry name" value="tRNA_Me_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20259">
        <property type="entry name" value="tRNA_Me_trans_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="tRNA-specific 2-thiouridylase MnmA-like central" evidence="14">
        <location>
            <begin position="796"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-specific 2-thiouridylase MnmA-like C-terminal" evidence="13">
        <location>
            <begin position="915"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="107"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="155"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="386"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="439"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="487"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="163"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="178"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="389"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="495"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="510"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF20258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF20259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1739243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1016" mass="114061" checksum="F94CA176D50D1024" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCF8</accession>
    <name>A0AAD9DCF8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007016</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCF8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="305" mass="34202" checksum="D6853190603546E0" modified="2024-05-29" version="1">MMDEMMVDDFGDMMGGGGEFGGGSDYFDNKTQLKLTARHLFCLAAEGITLPKSTTLDESDDPSIHYIIKKTLGLVTEHKETLRGHDVHVWYPNKDQGSEGMLRVLNSAFEGSLTYNFDSEPAEDGQDDLYRFGTSLRNFIEPASPSWLIQNINFRCNLSEEQRSYVHPILAGVGTKHHDDNDSFTKGNTRRLATGYPISVLNLDCEGCEYNLIPSMHETSFKSIGLILGRTNWGFIPTSKKPSSERAEDTHKRVCTHYNFARRCKECCDFPTLPVRPRLPSTTVVENGEFGDADVEDEANISSQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCN3</accession>
    <name>A0AAD9DCN3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCN3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="10"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="62" mass="6671" checksum="35DF5FD001191EE9" modified="2024-05-29" version="1">MPSKKKAKCKDKAKKKAAAAAAAAEKAEKQEELLDSLQSRCAKQEDALLEEAIKLAAAEKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEX1</accession>
    <name>A0AAD9DEX1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aspartate carbamoyltransferase</fullName>
            <ecNumber evidence="3">2.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_005794</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the condensation of carbamoyl phosphate and aspartate to form carbamoyl aspartate and inorganic phosphate, the committed step in the de novo pyrimidine nucleotide biosynthesis pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>carbamoyl phosphate + L-aspartate = N-carbamoyl-L-aspartate + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20013"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:32814"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.2" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEX1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004070">
        <property type="term" value="F:aspartate carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1370:FF:000002">
        <property type="entry name" value="Aspartate carbamoyltransferase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="entry name" value="Aspartate/ornithine carbamoyltransferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002082">
        <property type="entry name" value="Asp_carbamoyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00670">
        <property type="entry name" value="asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002032">
        <property type="entry name" value="PRK00856.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45753:SF6">
        <property type="entry name" value="ASPARTATE CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45753">
        <property type="entry name" value="ORNITHINE CARBAMOYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00101">
        <property type="entry name" value="ATCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="Aspartate/ornithine carbamoyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00097">
        <property type="entry name" value="CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aspartate/ornithine carbamoyltransferase carbamoyl-P binding" evidence="10">
        <location>
            <begin position="25"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Aspartate/ornithine carbamoyltransferase Asp/Orn-binding" evidence="9">
        <location>
            <begin position="197"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00043884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1743173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="352" mass="38267" checksum="7626A24C86ADF588" modified="2024-05-29" version="1">MTSASNDLSAITNTLTDDVSSWEGKNLISVTQMTTSGILRLFETAAAMRDLVRSKGGDDRLKHKVLASVFYEASTRTSCSFQAAIMRLGGTFLHVDGGKGGNTSASKKGESLEDTIRCLECYTDVTVLRHPTTGSVQQVALGDGTVKPVINAGDGVGEHPTQALLDFFTIFDELGLSLDVDNGNNTADNSHTGPLVVVLLGDLKHGRTVHSLAKLLARSSLKHELVLRYCAPASLEMPAHVKEYVQQCTNVKQEEYSDMSEAVKGANVLYVTRVQKERFETTEDYEKVKGAYVVDTSLMEAAPQGMIVMHPLPRVDEISTDVDSDPRACYFRQMENGMFVRMAILALILGAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEY5</accession>
    <name>A0AAD9DEY5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF1295 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005901</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEY5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010721">
        <property type="entry name" value="UstE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251:SF15">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE (DUF1295)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06966">
        <property type="entry name" value="DUF1295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042060120" evidence="2">
        <location>
            <begin position="19"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="288"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="342" mass="37036" checksum="C51DFA12839AF575" modified="2024-05-29" version="1">MKSTSLLASFVVLRGAASFAPTNYYHLHHTTIKQKRQQQLQTSLYIRGGGDSMSSSSLSSVLGPAADAVGSALVSGTPLRAVGGMWAVSSLVIVPLTFIRQGYSFSVGYGFSVAAMALTLLSSFDISLSTLTSSAPAILTATTVIYGLRLALFLLLREFSVDSKRKQIKSFDKTPRLKRTPLALSVSLLYAFMCSPALFALRGAVKAGSVWEKVQLVSTGVAFFGMILESVADQHKYEAKRKSKETEDKFVGPSSWSYKLVRHPNYLGEILFWVGLFGAGSVSFGKSIVAWLCGSLGLAAILSIMLGSSGRLDAKQQEKYGGQPKYEEWKDAVKYSVIPFFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFM8</accession>
    <name>A0AAD9DFM8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000008">
        <property type="protein sequence ID" value="KAK1744075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFM8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="64" mass="6245" checksum="1C1C887E0DA569BA" modified="2024-05-29" version="1">MSLAATGGAGMAGGGGLAMSAMAHGGPSAMATHQAHSQQHGHSSIPGGTHSALEHRMRPSVQIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFY9</accession>
    <name>A0AAD9DFY9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glucose-6-phosphate isomerase</fullName>
            <ecNumber evidence="1">5.3.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002898</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.9" evidence="1"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFY9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1746291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="53" mass="5964" checksum="7A38AAD74F7E4F39" modified="2024-05-29" version="1" fragment="single">CLTATTLVTSLHHYSNAPTYHNSLPYNSLHLHSVMILNSISDTYYPIVIDAYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGD9</accession>
    <name>A0AAD9DGD9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine-protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004385</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGD9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010506">
        <property type="term" value="P:regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045269">
        <property type="entry name" value="Atg1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348:SF68">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE ATG1C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="14"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1745094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="460" mass="51007" checksum="BABBB03B6ABAF9BE" modified="2024-05-29" version="1">MGNAKIIDQSGGFDTLPSRGGRNSLQRDFRVDQLDQAIISEDPTWETTDEMVAVKVINLAKYRSLHGRSLENPVNELAALQLLGNYHPSIICLVDALQNDTHLFIVTPYIPGGDLSSRVVADMENSPYGRVHESQAKIWFQQLLSAISHLQKKGVCHRDLCMNNIVVDDFGDLRILDFGLCLRVPFADPNNRHLVTDVSADTSRRLMKAQGQAGSCAYMTPEVALNMGVFDGFAVDLWSAGILLFEILVGKKPFAMPDPNDTNFRRISIDKDLDGFLQAKNIHLDSSIVNLLQKMLLADPQQRLTLSEIVDHPWMRGSHGAASPEPSAADRMSSWFVANDAIDDADDMNISQFNRLRADTTSTIFTLEKEMMEMDEGTVESCSEDRLSPFSDILIEGEETDRSFKPQGFPSNIKSKSWWRGVIKTIYASISSLVVKKSSKNDIATFSGANNQVNATGSLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DGT1</accession>
    <name>A0AAD9DGT1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_002565</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DGT1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="537" mass="61088" checksum="151EC9F45B428020" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DI05</accession>
    <name>A0AAD9DI05_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Translocation protein SEC62</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_000480</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SEC62 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DI05"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031204">
        <property type="term" value="P:post-translational protein targeting to membrane, translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004728">
        <property type="entry name" value="Sec62"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12443">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12443:SF9">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03839">
        <property type="entry name" value="Sec62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="150"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1748541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="319" mass="36948" checksum="020BAC295EBAE986" modified="2024-05-29" version="1">MAPAAKEFYEDQKNLNKLCNFLRSTDGPAVREAIMMDKRVYYIKGEKLVNFMVEPKKGTKWPKELPRFSSRPEAITVCKELCNIQYIHRSEKVAKGELEVARVRDFDESAYFTWIYEGDMTNKNLMTTALIIGFLCCTCFPIWPNFLKVFVWYMSVSLLIFIFFLVTLRAVVFLFVWIIGYEMWFLPNLFDESLGFCESFVPVISCEKTKDGQLMYRVGVFVAFSSFCYWAVTQPSEFDGFVKGQGDFIKDLYAGTLLSDISQKDKENIDKPKMPSLEDLLKKLDSEDEEEKELSEEEAAEALLNSLVEDSEDIDDEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJZ3</accession>
    <name>A0AAD9DJZ3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="26">Ras-related protein Rab-12</fullName>
            <ecNumber evidence="8">3.6.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="27" type="ORF">QTG54_000918</name>
    </gene>
    <organism evidence="27 28">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="27" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="27">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="25">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="25">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasmic vesicle</location>
            <location evidence="4">Autophagosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Endosome membrane</location>
            <topology evidence="5">Lipid-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Golgi apparatus membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Lysosome membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Recycling endosome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="27">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.2" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJZ3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005776">
        <property type="term" value="C:autophagosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055038">
        <property type="term" value="C:recycling endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003925">
        <property type="term" value="F:G protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00154">
        <property type="entry name" value="Rab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000568">
        <property type="entry name" value="Putative Ras-related protein Rab-12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17" id="KW-0072">Autophagy</keyword>
    <keyword evidence="24" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="13" id="KW-0967">Endosome</keyword>
    <keyword evidence="18" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="19" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="22" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="21" id="KW-0458">Lysosome</keyword>
    <keyword evidence="15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="20" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="23" id="KW-0636">Prenylation</keyword>
    <keyword evidence="16" id="KW-0653">Protein transport</keyword>
    <keyword evidence="28" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00011984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="ARBA" id="ARBA00047660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="ARBA" id="ARBA00067813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="KAK1748979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="229" mass="24638" checksum="AD030F8FF6959FB4" modified="2024-05-29" version="1">MSNRATSTTSKPPLYKIVMLGDSGVGKTSLVARLTNPDRPLNHDISATMGIEFDTQMLDTPHGKVKAQIWDTAGQERFARVLLPTYFRKAKGVILVYDVTNAKSFESLGERWMTQLNDHANSEDLAKLLVGNKCDLEGSREVTKEKAEMFCAEFGMEHLETSAKSGENVLKAFERLITIVHEKSLTAGRGKAGIKGMDGAASGGLKLDEGNVRADGASVAAENSGACGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DKM7</accession>
    <name>A0AAD9DKM7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_001219</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DKM7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1749280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="84" mass="9499" checksum="E98CE2BF91C395FE" modified="2024-05-29" version="1">MNEKYMCVNKIVPNITSKTDNKAHSNQPREFPLAPISKSSTIIDLINHRASGTTSQGERGNYVVMKQHGYNHVLNLRRFTDNGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DKW0</accession>
    <name>A0AAD9DKW0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DKW0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026795">
        <property type="entry name" value="SHFL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15135">
        <property type="entry name" value="UPF0515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1749128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="451" mass="50145" checksum="FDD4416AC9CD9902" modified="2024-05-29" version="1">MSDEFPTPLEIKALAEDYGYVERRSEVSYTLFFREDKPEQEGQPILMNIFYTTRGIMTKLPHPKQGYNEMWRRTAYDSLESLAMFFENPRTHSGKGYRQAKNALSGCAQCGMQKKKKDYTPAQWRKGAGKCICKDCSSGGSNEDSGANGEGQVPTLTLEALEQHNRFTIKNENKTLERRQFNCPVCPKEGRGKQCFFKRVPQIKPICKCPKCKKIKQDDCERLYPIPKGEEKGYGHYRCTGCKSTWGSSRSIANVGQECHSCNLAGKPNVFIKPFRVEVYKSGHKGGIAGGGARPAGRRMRRVPKEPISEDSTTDGAYSSFDAQRFQSKGGGSNSLDRTSASSSFDWQVVNEEQAGEETAPPNSRLAQYKPSHKCEGCATGICRSRKLPVSGVHDLHDGDTASTSGSIMTNSVVDKSEFPDRDIDFDDWEDDDDGSDIYVTVGSNGKILRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DKY9</accession>
    <name>A0AAD9DKY9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Bromodomain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_001142</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DKY9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050935">
        <property type="entry name" value="Bromo_chromatin_reader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027353">
        <property type="entry name" value="NET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038336">
        <property type="entry name" value="NET_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22880:SF225">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN BET-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22880">
        <property type="entry name" value="FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51525">
        <property type="entry name" value="NET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bromo" evidence="4">
        <location>
            <begin position="27"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="NET" evidence="5">
        <location>
            <begin position="158"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="131"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="259"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1749203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="283" mass="31935" checksum="82A7C2C1EAB248C6" modified="2024-05-29" version="1">MVEGAARDAGEIAESLRKMAKMVNNLSARADCEPFREPVDWKALELYDYPKIIKKMMDLGTIKRKLDKEKYSDAAECADDVRLVWKNCMTYNADGSDFYRLGESYSKRFEERFQKLVDEFGEDVICGNIAAQAAPPSKKKPKTSPVPNASANKKHKSDKKSFDPKGIIPLDVRTRFAARLQRLSGMELGHVLSVIDEICPEALEEPPEDQLRSDAQRMTKKHNYALDEFDGGSQIEIDIDAIPSHIFGELDVYVKEQVSGRGRGPWSDELLTEDGTKKKKVKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2LBC2</accession>
    <name>A0A7S2LBC2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cytochrome c oxidase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_011840</name>
        <name evidence="4" type="ORF">SMAR0320_LOCUS10487</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="HBGZ01014654">
        <property type="protein sequence ID" value="CAD9601454.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S2LBC2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.140">
        <property type="entry name" value="Cytochrome c oxidase, subunit VIb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048280">
        <property type="entry name" value="COX6B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036549">
        <property type="entry name" value="CX6/COA6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003213">
        <property type="entry name" value="Cyt_c_oxidase_su6B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46281:SF8">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 12, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46281">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02297">
        <property type="entry name" value="COX6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47694">
        <property type="entry name" value="Cytochrome c oxidase subunit h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CAD9601454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1737554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="109" mass="12655" checksum="8A4113CE4EC56C10" modified="2021-06-02" version="1">MTKPDIEAYKLNKIFTAPVGDLSAEQQELLNEVKATRTTPRDNRFAGAQNQANHCWNRYNEWLVCLKSTKDEEGCKNMRNYALKICPSIWSNKWDEERDEGIYPGIKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRA0</accession>
    <name>A0AAD8XRA0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_017106</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="mitochondrion" evidence="2"/>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000083">
        <property type="protein sequence ID" value="KAK1732065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRA0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="157" mass="18808" checksum="1C80CC536F6FD779" modified="2024-05-29" version="1">MDFNLKTYKRLKIKYYLKTINFFFFFHGASLDSESWIKTEQTLVKNKLKYYRVFNTLMTKTLNYSIFKNLTTLLHGPIILINSDHLKLTPKKLKNVNPLVNLLCLKLNNKIYSRKQIKNIKELSYIENVSIFHKSMKSLIKMPYYKFRSKKPLLISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRP2</accession>
    <name>A0AAD8XRP2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_017033</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000077">
        <property type="protein sequence ID" value="KAK1732258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRP2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1732258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="97" mass="10304" checksum="DDB7DFB9C8A716D0" modified="2024-05-29" version="1">MLSNNEINHIHACQDNETKKRAATATKATKVPSYKANPAATAALQAVLASAQDGDGVVNPDLLQKALSKGFSRAFIDAKVDEQEALNVKPAAKKMKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XS62</accession>
    <name>A0AAD8XS62_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_016824</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000066">
        <property type="protein sequence ID" value="KAK1732430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XS62"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1732430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="17" mass="2065" checksum="AAE489CBE9C8986D" modified="2024-05-29" version="1">MRRRSCFGRISIILNGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XSP8</accession>
    <name>A0AAD8XSP8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016338</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000055">
        <property type="protein sequence ID" value="KAK1733007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XSP8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16364">
        <property type="entry name" value="T3SC_I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="592" mass="66273" checksum="9579144601F90CB7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XST8</accession>
    <name>A0AAD8XST8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000057">
        <property type="protein sequence ID" value="KAK1732830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XST8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="473"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="617"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="619"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="647"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="719" mass="76865" checksum="1CF8B1CEF07FB26E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XTR6</accession>
    <name>A0AAD8XTR6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6824 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_016073</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000052">
        <property type="protein sequence ID" value="KAK1733216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XTR6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049227">
        <property type="entry name" value="DUF6824"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20710">
        <property type="entry name" value="DUF6824"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6824" evidence="2">
        <location>
            <begin position="7"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="401"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="416"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="425" mass="47047" checksum="106AA35E48579F9C" modified="2024-05-29" version="1">MEAKQNDVLSGRGACFNYHPGNKKFRTILDTYMDAYTTGTKKRKMMISKAIVEAIYSMQPPGRFLKKCADTGQWRELTRREAADKAAQAMAYAVRTSRKVAKKQSSIPLLTTTSQPPPPPFIGDGLAGGSSSPKTKAHHVPANLASDWGAKWDTTDASSGADHDNNGGREELVSRNSSRQQQLLRFQQTSRSATLPTTSAGAPTNRLAQMQMIARTQQEQQYYQQRQLSLQYLMSQQPSLGFHNGLPYRSHPSSQPLSAPSSSAQGMLLPPNNFLRQEYLSRGNYGADAQLSALLQRERNMLSNPNPMHSMMGYQQSIFGTDIAPSYEAQQMQQMQRRRAMMQHQLSSLTDTSVECIPSRRQSSQSLDLLQQAVYLQQKSPQDLPPPPVINSTSKAELSAQSTPSSTPQTQQGGDGKLKDTEDDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV84</accession>
    <name>A0AAD8XV84_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_015293</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000042">
        <property type="protein sequence ID" value="KAK1734035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV84"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1734035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="591" mass="65766" checksum="27CD389EC286E858" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XWG7</accession>
    <name>A0AAD8XWG7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD-dependent oxidoreductase</fullName>
            <ecNumber evidence="2">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014222</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XWG7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF150">
        <property type="entry name" value="OXIDOREDUCTASE TDA3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="204" mass="21655" checksum="BB57C2D21DC05327" modified="2024-05-29" version="1" fragment="single">QLDIGKVVEAILDGDGSIRGVKLEDGTTVECDALVIACGPWTDATKSWMGVKYHSILIQSPRVLNEAVFFSGHGDPEVYPRPDGDAYITGFPDPAMVVTESPGKEEVRPEVVSRLVDATKKVSSLLGTITPHTEQACYLPTTNDGIPVIGEIPGVKGAFVGSGHGCWGILNGPATGEAMAELLTEGETKHVDLKLLGVDSPYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XYI0</accession>
    <name>A0AAD8XYI0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_013194</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XYI0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1736058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="123" mass="13993" checksum="CEB91987D1848C16" modified="2024-05-29" version="1" fragment="single">VLQLFIVKERVVHGVTRVIGSPVSTWYIVIILCLSRTYVPYCTYKYCEYDTLIFFITTARSTQKVKKLCYDQLPYSVKPKGSSTATPSSTDPALSPVVPRAVLAPCPPFVDWSFVPPRDWLWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZ82</accession>
    <name>A0AAD8XZ82_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DnaJ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_012663</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000028">
        <property type="protein sequence ID" value="KAK1736641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZ82"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044632">
        <property type="entry name" value="DNAJC25-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44176">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44176:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="J" evidence="7">
        <location>
            <begin position="69"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="196"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1736641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="314" mass="35320" checksum="E68CED0A8ECFD6E2" modified="2024-05-29" version="1">MAQESDNGAAASAESGSSSSESAKGSEEAPKKEEPQSPKVKQNNASSSSSSDDWGSFYDPNNIFCGKYDCYKILGFDYETWGSAPPTLKEITKSYRGLSRLWHPDKNKAKAYEILTNSESARNLTTTVIAPMNTSKVWIFCLWTYAPKSDASIIELQWKTGAPVKGEGIAILAENREKAIEAALSNGDTPKKKEKGPRLTSKEKREKEQLVNEIDDFGAGFRKPTYKDLLVIKMVKWPYYLGSATLWWSKYGIRRMRKLELNAEEREVLTKNAVGEVAWAASSDEERATMVTLELWVSDNLVEWREEQDMKRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZ92</accession>
    <name>A0AAD8XZ92_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_013048</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZ92"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009858">
        <property type="entry name" value="DUF1415"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07209">
        <property type="entry name" value="DUF1415"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042232957" evidence="1">
        <location>
            <begin position="25"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1736448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="402" mass="44390" checksum="A8A38C122FBE91A9" modified="2024-05-29" version="1">MHHQVHFALIFAISIFAGGSITEAFQFPKIKFVGLSTAEKYDENEPKNRVKKGLEEAALLQQSLEKHCNKNDSLIRWEPQITESYEAAQVIFQEVAQSGNKRRCLVSFPSLTRPADLDKLSTVLQSSKCKQLLGLDSVECELYPSSPAPYIHIKFDKSVAGDAMAEDHSDVTENAASATKGWMKEFLGKYRLCPYTSSASRAAVGLASVGVPVGGVHIQVTEPTTSSSSATKAARIVDAFWTEVVTLMQSSQDEWATSLVVFPEYDDEFELFVEVCDGIIEPTVVATQATEVIGRAWFHPYYDADLVGHTDVIAGHAVPHKMVEGFMNSLNLESGLGKVETIEFEELAASNNLVRHTPHATINILRRSQLKAAAEYEKGLGAKRPKPNYIYVRNAIRLSNHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XZF3</accession>
    <name>A0AAD8XZF3_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="4">PPIase</shortName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_013029</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XZF3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01926">
        <property type="entry name" value="cyclophilin_ABH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000002">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0697">Rotamase</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041915912" description="Peptidyl-prolyl cis-trans isomerase" evidence="5">
        <location>
            <begin position="39"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="50"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1736429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="214" mass="22950" checksum="3F1E578690AEDA28" modified="2024-05-29" version="1">MVIAATRFYRSLSFNIKMKTIIALLSLVCLALLQGSTASGDGPTITNKVFFDVAIDGGEGGRIVFGLFGDNVPKTTENFRALCTGEKGVGKAGKPLHYKNSIFHRVIPNFMLQGGDFTDGNGRGGESIYGEKFADENFELKHEGPFYLSMANAGPNTNGSQFFITTVKTPWLDGRHVVFGKVLEGEDVVKRVEGVGSNSGATTKTVTIVDSGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y1B7</accession>
    <name>A0AAD8Y1B7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cyclin-dependent kinase 2 homolog</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cell division control protein 2 homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">cdc2-related kinase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">QTG54_012112</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">May form a complex composed of at least the catalytic subunit CRK2 and a cyclin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y1B7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030332">
        <property type="term" value="F:cyclin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000082">
        <property type="term" value="P:G1/S transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010389">
        <property type="term" value="P:regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000375">
        <property type="entry name" value="Cell division related protein kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000706">
        <property type="entry name" value="Cyclin-dependent kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF254">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 14 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 15" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="16">
        <location>
            <begin position="8"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1737245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="298" mass="34341" checksum="2C145D1DDD41411A" modified="2024-05-29" version="1">MDRYQKIEKPGSNLGEGTYGVVYKARDRHTDEIVALKRIRLEVEDEGIPSTALREISLLRELTHENIVDLRDCVQQDGKLYLVFEFLDRDLKKALESYNGLLDPMLVKSYLFQMCRGLAFCHARGVMHRDLKPQNLLVSRDGVLKLADFGLARAFCPPIRPLTHEVVTLWYRPPEILLGSQTYAPPMDTWAIGTIFVEMVTKRPLFPGDSEIDELFKIFRQLGTPNEQVWPGVTSLQDWNTSFPIWFKSKFSKTFLDNVDANGVELLERFLAYSPKDRITAKDSLNHPFFDDLDKENI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y280</accession>
    <name>A0AAD8Y280_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_011611</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Sodium-phosphate symporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000023">
        <property type="protein sequence ID" value="KAK1737839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y280"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101:SF80">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="155"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="444"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="484"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="527"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1737839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="561" mass="61528" checksum="8577CC37F8B165F4" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y314</accession>
    <name>A0AAD8Y314_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010756</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y314"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="342" mass="36397" checksum="C3CCA24885AFD384" modified="2024-05-29" version="1">MLKCKLNTSIAKQPTMWTKKTSLAALLISARYGSGVDAQKIRSPKSSKNPSIKSSKAPTSKAGKKVCLEFGFLNDVVGEGSPVAIGADGPNGFLACYPGFPNDLTAPPLASAVCCAELSLCVAGYASSECDPYFECLQDPDNGPVLVGDWWLQRDVNNGEMFFEDDAVCGRINSAALNSRTRFELWNDVHLGMDLGLFKEFSVGYDYRALGGGSGGYLNMYLRVDETSTAYYDCNLVFNIPNAVGTGTLLVTPETVVSSARTFSSGDANGCIAGTTIEDYLAANEDAVMGVGNGELYTFALNTGSTDQDNSGSEICWGDVSIKHVDEAGTVYATTFEFTTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y396</accession>
    <name>A0AAD8Y396_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FAD-dependent oxidoreductase</fullName>
            <ecNumber evidence="9">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_011284</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1737990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y396"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006093">
        <property type="entry name" value="Oxy_OxRdtase_FAD_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00862">
        <property type="entry name" value="OX2_COVAL_FAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042251077" evidence="7">
        <location>
            <begin position="21"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="8">
        <location>
            <begin position="145"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="47"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1737990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="702" mass="76116" checksum="40DBA58BB49067E1" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y3F4</accession>
    <name>A0AAD8Y3F4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase</fullName>
            <ecNumber evidence="7">2.4.1.122</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_011006</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.122" evidence="7"/>
    <dbReference type="EMBL" id="JATAAI010000021">
        <property type="protein sequence ID" value="KAK1738337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y3F4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016263">
        <property type="term" value="F:glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026050">
        <property type="entry name" value="C1GALT1/C1GALT1_chp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033">
        <property type="entry name" value="BETA1,3-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033:SF14">
        <property type="entry name" value="GLYCOPROTEIN-N-ACETYLGALACTOSAMINE 3-BETA-GALACTOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1738337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="276" mass="31734" checksum="2AB9F4C464962D95" modified="2024-05-29" version="1">MWQKVRAMWVYVYVNYYDSYDWFHIGGDDMYVLVENLRLYLESEEIATASKGGEQPLLLGQIFHQNFYSSATYVTGGGGYTLNKAALKMLVASFPNCAPHDVTSVEDVLVTQCLQKGGIEPYRTTDETGAERYNHIKPEFEFNFDPKKHPFFWYSYFSGNKNIGPERVVKRAVSFHLKDSKPTVENMMRRVHAILYGHCANVTLGPPVPTNPFEIARQAIRLNKQTWSDGKFLGWYWKSPLLQCELNAEAGEICICSMVKQGKKEVKVCKKQTYYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y479</accession>
    <name>A0AAD8Y479_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF2358 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_010488</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y479"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018790">
        <property type="entry name" value="DUF2358"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34123">
        <property type="entry name" value="OS04G0578200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34123:SF1">
        <property type="entry name" value="OS04G0578200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10184">
        <property type="entry name" value="DUF2358"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042144400" evidence="2">
        <location>
            <begin position="22"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="278" mass="30867" checksum="F63AA0655128AA33" modified="2024-05-29" version="1">MMTKALAVLVSTQLLILDVSAFCPLSRPLCPSVRVRSTAPNNDHLQRTQASHIFATDDSNDNNTGSSSSYESSASVTKGLVSSLTSLTNNIFGGTSREPADTADLETRLYTPPTSPEELLTRIQKEYTQNNYLWTGNIDTSSFVSNCTFTDPTLSFIGVDKYVQNVGNLVPIVEYALGEEQISNSTLLDITLEKDKGYIQTRWNMIGELNALFWKPKIDVIGRTKFWYRQGETNGNDNGAVQVYFYDEEWEIPAGLALLQLVTPAGTIRRSDEERVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y5N2</accession>
    <name>A0AAD8Y5N2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">UDP-galactopyranose mutase</fullName>
            <ecNumber evidence="8">5.4.99.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_009119</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.9" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y5N2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008767">
        <property type="term" value="F:UDP-galactopyranose mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004379">
        <property type="entry name" value="UDP-GALP_mutase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015899">
        <property type="entry name" value="UDP-GalPyranose_mutase_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00031">
        <property type="entry name" value="UDP-GALP_mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21197">
        <property type="entry name" value="UDP-GALACTOPYRANOSE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21197:SF0">
        <property type="entry name" value="UDP-GALACTOPYRANOSE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03275">
        <property type="entry name" value="GLF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDP-galactopyranose mutase C-terminal" evidence="7">
        <location>
            <begin position="258"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1740169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="489" mass="56073" checksum="D16E3FFD0801CB22" modified="2024-05-29" version="1">MHSIRNPFRRNRDSAINNRRLRGPILLLVIGTCLLAYFSPPSDSTEPLLAVSKSKSKHPPAQVQLPIIKGVTVTEMDDTKPKEAANTTTTTTADKEDPFSKEYDNCIVGAGLSGSVIAENYATKLGQTSLIIEKRNHIGGNCYDYTDTETGIRVSLFGAHLFHTRHERVWEYVQRFSEWVPYEHQVLGIVNGKHVPIPVTIDTVNTLFDEKIASTEEMDEWLKKEQVTFYDEDGEEREAENSEEVALMRVGQRLYDLMFKPYTFKQWAKYPAELGPEVLSRIPVRNNHDGRYFSDPHQALPKDGYTAIFDKMLSSPKITVVTNTDYFEVRDKLKCKRLYYTGPVDSYFADLGWAKLEYRSLSFERVVKDNTPGYFQQASVVNHPQATDVDGKEVDFTRIVEYKHLLNQTSDKTIYFIERSKDGGEPYYPVPNDENKNLYKRYQEMAEKEEGVTFVGRLANYKYFNMDDAILNALELFDKDTKDIKTATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y627</accession>
    <name>A0AAD8Y627_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009428</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y627"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="151" mass="16680" checksum="ADCFDF5F5BFC0269" modified="2024-05-29" version="1">MASKIPPHVARELRRHVARTNPKAAPKTSSASSNNNTSTDSSFSRPKVVAGCVALAGTFYAVPYLFINWIQPLSERDDALVGGQIRRGAFNNSGSKDVGKDPYWDFKHGRRKKVGEDGCEEDGGYADLFNRDDPDQVEHGDQFVAKSKRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y664</accession>
    <name>A0AAD8Y664_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">PD-(D/E)XK nuclease superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_009488</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y664"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026350">
        <property type="entry name" value="GxxExxY"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04256">
        <property type="entry name" value="GxxExxY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13366">
        <property type="entry name" value="PDDEXK_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1739729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="283" mass="32175" checksum="12F51DF2E5F5C881" modified="2024-05-29" version="1">MMSSKKYYINNDVEVEELAAKLSKTIILDRDDENNIKKAETATPSLSPPRICDVRSFDDQIGKICQSLFHTLTSKQLEATYQRCLAIDLQHAGIKVLAQEREIKLQYKGRDVGTRRADIVLQTPLDKQWVVLELKALQNLTSEHMKQLEFYMYHFEIDIGYLINFPTDRGFPDLPSNAATYRQTILSGGDIMLSDRNLRGRHTNAQVQIIKVERVITKEQSQSAQIVTDATLVLSSAQPTIVCPVGRTTSGTFVVPIAKKTGEPCKLCTRYQSYCRYHKPIKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6F5</accession>
    <name>A0AAD8Y6F5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008699</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6F5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="173"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="251"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="410"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="484"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="565"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="589"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="769"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="413"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="448"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="493"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="513"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="529"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="571"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="590"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="615"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="655"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="820" mass="94478" checksum="9DC9A209086EA1AC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6S0</accession>
    <name>A0AAD8Y6S0_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycosyl transferase CAP10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009399</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6S0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
        <property type="entry name" value="Glyco_transf_90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="2">
        <location>
            <begin position="78"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="214" mass="24728" checksum="8167C809494D0B05" modified="2024-05-29" version="1">MSGVCKPKPKRCHKHKLSWFRARKFIEMIRMGLMQQKSNFPFSISSTNSTSSLEGGLPILLSEGDDLHCNVVTKQDHTPFPRLSWSIVAPKHGTWCQSIGIPSYSNWHFYHRNFQKQSDWVSKFQQNDEQYPWSNKSNNAVWRGSTTYDAPQYNQSSLNETPRGQLVKKGMEHPALIDAGFTRLIQKFENDKKAERETSVSKGMSMSDMMKYKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y6T7</accession>
    <name>A0AAD8Y6T7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_009429</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y6T7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052410">
        <property type="entry name" value="DRC5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24107:SF2">
        <property type="entry name" value="NLR FAMILY CARD DOMAIN CONTAINING 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24107">
        <property type="entry name" value="YNEIN REGULATORY COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1739670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="580" mass="64963" checksum="A6B4DD46257AC4C6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7G5</accession>
    <name>A0AAD8Y7G5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_008980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000016">
        <property type="protein sequence ID" value="KAK1740030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7G5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="86"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1740030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="658" mass="74694" checksum="FB32D80A9EDA45DA" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7G7</accession>
    <name>A0AAD8Y7G7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ankyrin repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_008532</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000015">
        <property type="protein sequence ID" value="KAK1740437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7G7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1740437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="214" mass="23983" checksum="03F6C44BD4AA198D" modified="2024-05-29" version="1">MSSRLSKKLLSPATSRILACSTRTGQLQLTKLGQRCHHLLPLTCGNVSLRNFAAESAPPSSYNPAYPPILFDLVLRSDWKSALKRVSSHPIEARYRHPRGYTLLHCAVEYGAPVELIDKMAKANPEALYMKDWQGRSIADVAIDSDTKVFLEKLSQSQDDLQKTKQEEGKTEEVDPNLSSSHMKLISKQLLDIETSCHRLRIQLDALVDKVEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y7K9</accession>
    <name>A0AAD8Y7K9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphoadenosine phosphosulfate reductase</fullName>
            <ecNumber evidence="5">1.8.4.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_007742</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PAPS reductase family. CysH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.8" evidence="5"/>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y7K9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004604">
        <property type="term" value="F:phosphoadenylyl-sulfate reductase (thioredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019379">
        <property type="term" value="P:sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002537">
        <property type="entry name" value="PRK02090.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46509">
        <property type="entry name" value="PHOSPHOADENOSINE PHOSPHOSULFATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46509:SF1">
        <property type="entry name" value="PHOSPHOADENOSINE PHOSPHOSULFATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="385"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="268"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="275"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1741264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="515" mass="59589" checksum="9C7AAE7583F9D0D2" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y865</accession>
    <name>A0AAD8Y865_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DUF4782 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_008069</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000013">
        <property type="protein sequence ID" value="KAK1741591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031968">
        <property type="entry name" value="VASt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47666">
        <property type="entry name" value="PROTEIN VASCULAR ASSOCIATED DEATH 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47666:SF1">
        <property type="entry name" value="PROTEIN VASCULAR ASSOCIATED DEATH 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16016">
        <property type="entry name" value="VASt"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51778">
        <property type="entry name" value="VAST"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="2062"/>
            <end position="2088"/>
        </location>
    </feature>
    <feature type="domain" description="VASt" evidence="5">
        <location>
            <begin position="432"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="domain" description="VASt" evidence="5">
        <location>
            <begin position="1088"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="36"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="333"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="368"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="750"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="992"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1028"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1467"/>
            <end position="1496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="2096"/>
            <end position="2115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="71"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="335"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="376"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="993"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1032"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1478"/>
            <end position="1496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1741591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="2115" mass="235248" checksum="F15DD20ACC731ADE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8E6</accession>
    <name>A0AAD8Y8E6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nucleolar complex protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_008172</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8E6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030690">
        <property type="term" value="C:Noc1p-Noc2p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030691">
        <property type="term" value="C:Noc2p-Noc3p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005343">
        <property type="entry name" value="Noc2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12687">
        <property type="entry name" value="NUCLEOLAR COMPLEX 2 AND RAD4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12687:SF4">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03715">
        <property type="entry name" value="Noc2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="168"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="587"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="184"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="607"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="620"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1740920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="664" mass="75233" checksum="EEBE212A0FD23E6B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y8K7</accession>
    <name>A0AAD8Y8K7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphodiesterase</fullName>
            <ecNumber evidence="6">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_007392</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="6">Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cyclic nucleotide phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="6"/>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y8K7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023088">
        <property type="entry name" value="PDEase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023174">
        <property type="entry name" value="PDEase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00387">
        <property type="entry name" value="PDIESTERASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00126">
        <property type="entry name" value="PDEASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDEase" evidence="8">
        <location>
            <begin position="892"/>
            <end position="1253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="216"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="676"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="230"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="685"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="990"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="990"/>
            <end position="994"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="994"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="1030"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="1031"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="1031"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="1031"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="1158"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="1158"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="1209"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1741819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1256" mass="142549" checksum="F546A97E9BB1D70E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y906</accession>
    <name>A0AAD8Y906_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007602</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y906"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042015688" evidence="1">
        <location>
            <begin position="21"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="330" mass="36086" checksum="DDB93DC55C44D750" modified="2024-05-29" version="1">MKFSTAAAILALTTSIQAQAQTELIFDDTPAFALGGPATLLFDSAKAQAEAETGDNTRLLRGKRKEGKKEGKKKDRKACDPSDVVLADYPQWNAEKGYWIGEYSFYGPDGKPYASAWPYEYDAYKGFITGNVEGNAYRQRNVFFYPPARNSTCERLQPNVTGDGECGANGNSLVFFADQEATTCSDNPELAGDVNGPFNSAFGPLPTTTELVGDGNALLYQVYVPGNPNPLQSQLTTLTKGLGSDEFNLRTRTAQGLNFVTGQQAYASFYRERKVTEEEFYSEMNNTIAEYNILDSDLCFLDGGAGRTPVANYTAGYEQCVAHLQTSFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y913</accession>
    <name>A0AAD8Y913_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TBC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_007614</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1742041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y913"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045913">
        <property type="entry name" value="TBC20/Gyp8-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20913:SF7">
        <property type="entry name" value="RE60063P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20913">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 20/GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="152"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="570"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="160"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="181"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="571"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="586"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1742041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="818" mass="91530" checksum="85C8892EA17C9DEC" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y916</accession>
    <name>A0AAD8Y916_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">vitamin-K-epoxide reductase (warfarin-sensitive)</fullName>
            <ecNumber evidence="3">1.17.4.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_008238</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VKOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.4" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1740986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y916"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047057">
        <property type="term" value="F:vitamin-K-epoxide reductase (warfarin-sensitive) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042373">
        <property type="term" value="P:vitamin K metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12917">
        <property type="entry name" value="VKOR_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.130">
        <property type="entry name" value="VKOR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012932">
        <property type="entry name" value="VKOR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038354">
        <property type="entry name" value="VKOR_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042406">
        <property type="entry name" value="VKORC1/VKORC1L1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14519:SF8">
        <property type="entry name" value="VITAMIN K EPOXIDE REDUCTASE COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14519">
        <property type="entry name" value="VITAMIN K EPOXIDE REDUCTASE COMPLEX, SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07884">
        <property type="entry name" value="VKOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00756">
        <property type="entry name" value="VKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0874">Quinone</keyword>
    <keyword evidence="11" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="Vitamin K epoxide reductase" evidence="13">
        <location>
            <begin position="28"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1740986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="197" mass="22032" checksum="C1DBBE969E88E194" modified="2024-05-29" version="1" fragment="single">LPPHLLRHLIGTRCSRSHHLLPTITPPPHIMAINNSILSILGFILSAYSVYVEHKVEQNLHDDNINPDEEFRALCDIDAIGASCSAVFQLPEGKMLSFFGLVPKDSALDIPNGILGMLFYTYVFIRCNMRSSELILLDRRLNAVVCSLALASSVFLARKLYIIKEICVVCLTTHVLNTTVFCRAILEVVKKQKDKVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9N7</accession>
    <name>A0AAD8Y9N7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">2Fe-2S ferredoxin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_006788</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9N7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="4">
        <location>
            <begin position="41"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1742223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="205" mass="22684" checksum="43692E70EC135B3B" modified="2024-05-29" version="1" fragment="single">PNGSISSRISSPSSSTTLIYNTNPEVGLETSSNHNQDEISYPVQIIHQGRKTTINVHENEPILQALERQSTIAGSRDQMALALSSIPHECRRGNCLTCASKNVKRATSDNNLVVNVDNGLSPTIASELTKSGYVLTCCSYVTGPGVVLELDQNNEVWDAVYRQRLCDGDTKQIALEAQARLLRRVDEENVEKWKNKMKKVLSEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9T1</accession>
    <name>A0AAD8Y9T1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Helicase-associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_008347</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9T1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF83">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase-associated" evidence="4">
        <location>
            <begin position="32"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1741095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="242" mass="27058" checksum="2ED1C75F118F7CF3" modified="2024-05-29" version="1">MCNVVLMLKSLGIDNLLAFDFMDAPPPDTLIRSLEQLYALGALNDRGELTKMGRRMAEFPLDPMLSKTVIVSEKYKNLSTVSMLSIGTSVFYRPKEKKVHADTAHQNFARGGGGDHIALLRCYSDWADLTTHHSGALRTLSKFVISERRETLCERVEVDPNISNPEDVESILKAVTAGFFYNTARLGRSGDYETVKQRRTVYIHPSSVLAKEEPLPGWVCYFELALLLRVHETGSTNQSMAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8Y9X0</accession>
    <name>A0AAD8Y9X0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_007476</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000012">
        <property type="protein sequence ID" value="KAK1741903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8Y9X0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1741903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="420" mass="48323" checksum="8725CF194F0752B3" modified="2024-05-29" version="1">MAALTRATKANYIIHDRIQAETTDREDHTFCGIMFPVKCKDILPLDHLVINSVAVRGALGPLTVWVTKSEDLNGEIQLSKKYWTKIYQKEHQPSFVGYKELDLSANPIILKPGQVKGIYIHSTRRGDEAIVYDNKAKQKTVDDSFITILPGRAHVSEKVFGSIPIWGWGSAWRDNREFVGQLKYGAVYKLWNPQENLSFGGSFRTAARILFMCQRRPESPFSKLPDDCLFFILNMMRWDWVNDTSVEMRREQKQRRRLRRQQMIQEADAIMDEENNDADANEQVVEGVILAEGIVLAEEEEEDEQAEDAQVDIDVNSDDDEEEEDLDFMEEDSNDDSEDADTSDNDDDESSDDDNEESSEEEEEEEYAWGDHVGSRSAFHYADDTSDSEASESDFERDENVRRIAIMRARRNILSFLRSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YAX2</accession>
    <name>A0AAD8YAX2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ADP,ATP carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_006933</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ADP/ATP translocase tlc family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YAX2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005471">
        <property type="term" value="F:ATP:ADP antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004667">
        <property type="entry name" value="ADP_ATP_car_bac_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00769">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31187">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31187:SF1">
        <property type="entry name" value="ADP,ATP CARRIER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03219">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041959488" description="ADP,ATP carrier protein" evidence="10">
        <location>
            <begin position="21"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="352"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="390"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="421"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="446"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="522"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1742368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="568" mass="61433" checksum="C7BBC07E7CF1D8D6" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YB89</accession>
    <name>A0AAD8YB89_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycine oxidase</fullName>
            <ecNumber evidence="4">1.4.3.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_006862</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.19" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043799">
        <property type="term" value="F:glycine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF289">
        <property type="entry name" value="GLYCINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="3">
        <location>
            <begin position="476"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="3">
        <location>
            <begin position="647"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="505"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1049"/>
            <end position="1307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="511"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1057"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1070"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1094"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1105"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1141"/>
            <end position="1152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1231"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1248"/>
            <end position="1259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1284"/>
            <end position="1297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1742297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1307" mass="141355" checksum="922087D0060B569E" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBD2</accession>
    <name>A0AAD8YBD2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cyclin C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006624</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1743027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBD2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20537">
        <property type="entry name" value="CYCLIN_CCNO-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000485">
        <property type="entry name" value="Lipoate protein ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02984">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01332">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin C-terminal" evidence="2">
        <location>
            <begin position="16"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="172"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="234"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="273" mass="29796" checksum="11C8447D5B932D02" modified="2024-05-29" version="1">MEWNVLTSLEWKIHPPTSMSFISHLLLLLPPQVDDACKEEIYALSRYITELSVCDSSFVEINPSSVAFAAILNSLEDRKYRKFISSSVRDQFVRSIERHVDIRQDDEHVAMARPKLKKLLKNSFAQDAASSSQGGSSSQTPQQQQLNVAQSVSSVTGSINGMQIQENKMDDSSISSKLSRLSGRSRHSRSSSLDSNISVNRRRVVPVGGGSSINANAMAQASPSFRSRPPPSPSNRSMSSTVMSTSPCSLSSRSSRSVFSRGSRVSPLALLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBD9</accession>
    <name>A0AAD8YBD9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_006250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBD9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1742653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="150" mass="17197" checksum="73BC6DEEF7F099D2" modified="2024-05-29" version="1">MPLKDGMIEDNAFAFCPNLTTINLVGGIHNTIASLHLESWRNEMKEEINRINQVLPITPLKTGAIQQWIRSVIRRIDHYKTEHKVMLKEATTLLELALWKAKVDEREKESLGDVITKKAKIDVQSKRSERRITSGANIVIKNVLPFLELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBJ1</accession>
    <name>A0AAD8YBJ1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006982</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBJ1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042268053" evidence="1">
        <location>
            <begin position="19"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="519" mass="59240" checksum="CF009B33627E23BE" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YBL1</accession>
    <name>A0AAD8YBL1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_007144</name>
        <name evidence="7" type="ORF">QTG54_013320</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000030">
        <property type="protein sequence ID" value="KAK1736184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000011">
        <property type="protein sequence ID" value="KAK1742579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YBL1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14809">
        <property type="entry name" value="bZIP_AUREO-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050946">
        <property type="entry name" value="AP-1_TF_bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11462">
        <property type="entry name" value="JUN TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11462:SF35">
        <property type="entry name" value="TRANSCRIPTION FACTOR JRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="6">
        <location>
            <begin position="31"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="93"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="167"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="93"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1736184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1742579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="346" mass="38079" checksum="0A7603DBE9DCAC8A" modified="2024-05-29" version="1">MTEADSTPDIVWSSRARSDSISSIASTSDDGERRLLARERNKEHARKTRLRKKEQLQSLKSRVNELEEEGRRLKQQIEACSVASILVGLSHGSSTGQEGMSGADSSAQPKNYGETLSGGKRKRFLSLDGEEPSPPPMELNIKGHITLVGGPAGEGKTQINWKTGVYFDDQGQRHQLTKKELEELRRERNRMHAKMTRDRKKCYIASIKRVITKLEDQNQHLRDTLDKSQALSANAAAAQLNVDMADEEASTSESSTGHKNLEASANALSVLDFAGQAAFPSSIMMGSNALESDFERLDSPPLLCSVETKKSLDEKPSTKLAEKKMDLSHILPSGAFTFNSNMYAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YC89</accession>
    <name>A0AAD8YC89_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pre-mRNA-splicing factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_006209</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044624">
        <property type="entry name" value="Mbb1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44917">
        <property type="entry name" value="PROTEIN HIGH CHLOROPHYLL FLUORESCENT 107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44917:SF1">
        <property type="entry name" value="PROTEIN HIGH CHLOROPHYLL FLUORESCENT 107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="810"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="230"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="400"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="464"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="569"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="634"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="707"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="43"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="101"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="143"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="156"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="174"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="206"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="274"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="400"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="426"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="517"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="542"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="573"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="601"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="719"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="729"/>
            <end position="740"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1743588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1465" mass="161652" checksum="7E71D12FDEEBFD5D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YD77</accession>
    <name>A0AAD8YD77_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CMP/dCMP-type deaminase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004854</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YD77"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="1">
        <location>
            <begin position="236"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="408" mass="45161" checksum="4F046E6D1018E434" modified="2024-05-29" version="1" fragment="single">DLVDLATLSNHELFTKVIAEISRCFKSRDKKERPKNWMSIAVQIAVAAAEGQPGCASDWVEQFNVFSSDNDTGNNTNDINFSEALSRLNAKECYMKRLNNVLGHPSLSLPNNILSVRHAAGLIRGSVLLSKEDNHNNDTVKGIQISVIKLLVRTMPQLGSTSPCDIFLAVQLPLLQSLDRSAFTNGGLSFPSKFSEQEFDYLLGLDCSDLDFDSVAQVGEKRNRSYIQHSKYTHVLEAAHLARKGAVRAQHGAVIVFPSPDDEIQVIGKGWNHDYLMDRAKTNKNKVVLHSECHAIADAIKRHGEDECFNELFPKATIFIVELESDFAYETCHPCPKCDPLLRAVGIMQVFHTTPNGNLTKMELSTPSCELLANENCSLPLKAACDEQGITCKRLDTAMKEAADEGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDB8</accession>
    <name>A0AAD8YDB8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004917</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDB8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="268" mass="28926" checksum="989767520488D786" modified="2024-05-29" version="1">MSISILLCTMLKRSQGKSLSATKSNDTGDDDVSKQQSNSTAAAASTVANSSTNAKPQSKYLPAAAFAQSSALSSQPKKKRMRRPNDDDDSDDDEPGWNITEEMKQMIQRSEWLRKELEDGGLRHLIEQIDAASDVEEEEEDNGNNNRRKNWGRNANKNGNTDISQRVLTLARTRHSHPKFATFMDRLLVTAGVLTDGGGGGGEANLFEGGESGRLELVTVPRRGGELVAAPAAAAAGEEVESSSEEEDSDDDSDSSDEDDSDESSTKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDJ7</accession>
    <name>A0AAD8YDJ7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WRKY transcription factor 19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006642</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1743045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDJ7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="529"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="603"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="371"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="537"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="608"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="666" mass="71814" checksum="C30EEB95C6109C7D" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YDP3</accession>
    <name>A0AAD8YDP3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000009">
        <property type="protein sequence ID" value="KAK1743120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YDP3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1743120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="793" mass="87190" checksum="32C94721B7322D72" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YES8</accession>
    <name>A0AAD8YES8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_004470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1745179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YES8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1745179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="151" mass="16519" checksum="35DC29494385BA87" modified="2024-05-29" version="1">MRVETLLSNGSVVLVDDSERLVIPINDASAHPIDDCGTLGDISGNLAGMTIGSFPGGPFQGVRAKVRVDDDGSVNLTLHLSTLICIEGRLDAHISNDALAAYVERGNFMSCMRMPFPLFMLLSLRHRLTESFSRHFISMSLTPRLNKSHFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YF01</accession>
    <name>A0AAD8YF01_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_004768</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YF01"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010433">
        <property type="entry name" value="EIF-4B_pln"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32091">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32091:SF20">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06273">
        <property type="entry name" value="eIF-4B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="283" mass="30809" checksum="DDCB2457EBEA5A63" modified="2024-05-29" version="1">MTWADDSEEQLEPAPAEYTGSAVPAGRPRLQLKPRSKAAAPQAAGGGSSSIFGAAKPREAVLASKGIDPTLVDKRVERKASVARLTAEQDRQVEALRKELTEVEEKLREANEQELPEEEYRVAAEEKREELNKLMKEFAEMNLKGPSADVKVEEGADTKGGKADGRKHYERPSERRRRLEAKRREEGGEGGGYGGHKSYDNEGGDDDAYKSFGSNRNYQSGGRSGGYDSNDRGGGSYGGGERGSYRGGGRGGERGSDRDGGRDGGGRSSNNYNEKYAQDRYNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YFJ2</accession>
    <name>A0AAD8YFJ2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">30S ribosomal protein S21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_003297</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YFJ2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1150">
        <property type="entry name" value="Ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00358">
        <property type="entry name" value="Ribosomal_bS21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001911">
        <property type="entry name" value="Ribosomal_bS21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018278">
        <property type="entry name" value="Ribosomal_bS21_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038380">
        <property type="entry name" value="Ribosomal_bS21_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00030">
        <property type="entry name" value="S21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21109">
        <property type="entry name" value="MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21109:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS21M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01165">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00976">
        <property type="entry name" value="RIBOSOMALS21"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01181">
        <property type="entry name" value="RIBOSOMAL_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042134553" description="30S ribosomal protein S21" evidence="4">
        <location>
            <begin position="19"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1745373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="108" mass="12598" checksum="38661B3B866E3983" modified="2024-05-29" version="1">MARLTILLVVLVAAMATAFAPVPLSRTVSTTALNGQTRVEVKIGEGEPIESALRRFKREVNKSGHLMDLRHKRYFENSQDRKKRKIVQARIRKRLERMNARRMRQRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YG80</accession>
    <name>A0AAD8YG80_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004171</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YG80"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="58"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="149"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="70"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="560" mass="62085" checksum="BE6649B28A2C1EF8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YHD4</accession>
    <name>A0AAD8YHD4_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pre-mRNA-processing factor 17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_003488</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YHD4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000034">
        <property type="entry name" value="Pre-mRNA-processing factor 17, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_b-propeller_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032847">
        <property type="entry name" value="PRPF17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43979">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43979:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="2 9" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="384"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="427"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="511"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="612"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="182"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00068146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1745564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="678" mass="74768" checksum="1F7F0ABE7DDEAAA5" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIA7</accession>
    <name>A0AAD8YIA7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BTB/POZ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003204</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIA7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14733">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="216"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="436" mass="48538" checksum="FAD75C9A16CE7ACA" modified="2024-05-29" version="1">MANNAGRQGAGGGNANGNNANNMNEHVEFTVKAEEDLYLTGSENTIRRVTADTNYSCLMLKTQRFSSLFRHYAKYHGLRKDDLEYHFVNPLENEDTPESVQLQRGDIIMVRKKRKVEPPEPAADDTEFFKDMKELLDDEEHMDTLFLVHPIPPSGTTASPGGKRKMSSSGGGGGAKGKKNDLDVNAIKREVDDSMDEDGNNGSSGSGNDNRDNLIEIRAHKCILTARADYFKALFRKMAGENSSGQRVGTFRESTECVIRVEPYFTPKIVRLMLEFMYTNRIECLKASSKLEVGLECPHRVTTDELLSLLHLADMWQLRDLKRLVEHELIRSHMNVNTVSRMYCATDDLHAKRLSKSCLEFIMQNYREVTGSVAFQEEMKHHPDLCIPVLKAAADLIPEPAHKKARTSTGSDMGKDTPGSGTGGGLASSPVPDSDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YIS8</accession>
    <name>A0AAD8YIS8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">LrgB family membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_001317</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YIS8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007300">
        <property type="entry name" value="CidB/LrgB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30249:SF0">
        <property type="entry name" value="PLASTIDAL GLYCOLATE_GLYCERATE TRANSLOCATOR 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30249">
        <property type="entry name" value="PUTATIVE SEROTONIN TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04172">
        <property type="entry name" value="LrgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042077932" evidence="6">
        <location>
            <begin position="28"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="345"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="374"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="409"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="432"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="486"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1747354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="522" mass="54059" checksum="8E88A5284F3C4A64" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJB2</accession>
    <name>A0AAD8YJB2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Signal peptide peptidase SPPA</fullName>
            <ecNumber evidence="8">3.4.21.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_002939</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S49 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJB2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07023">
        <property type="entry name" value="S49_Sppa_N_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1750.10">
        <property type="entry name" value="peptide peptidase (sppa) like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002142">
        <property type="entry name" value="Peptidase_S49"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047272">
        <property type="entry name" value="S49_SppA_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33209:SF1">
        <property type="entry name" value="PEPTIDASE S49 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33209">
        <property type="entry name" value="PROTEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01343">
        <property type="entry name" value="Peptidase_S49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041958667" evidence="6">
        <location>
            <begin position="21"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S49" evidence="7">
        <location>
            <begin position="1025"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="643"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="759"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="649"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1746332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1196" mass="133181" checksum="E1369411D07C7319" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YJW7</accession>
    <name>A0AAD8YJW7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001706</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YJW7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="280"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="359"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="515" mass="60570" checksum="3039A26D6E8247D5" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YK46</accession>
    <name>A0AAD8YK46_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_001826</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YK46"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1747863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="193" mass="21913" checksum="226E22E58DA55A43" modified="2024-05-29" version="1">MSIDRYQTQTLQTRDGEPTANLPTISNIKANKTVLNMPRIVTAVAFSAIISLSNGKLIGDVVKEGLRGAQEGHRALSNEEILKDMLGKEVFSFDTDECLIGVDVNGTATYGRCEIRRFPYCEGDTPHICFNRVNRQDKFWPDKNPHFYIDYKRIHCYPDIEGFTCSSCSPGRWCTPEGRCILDENLYSCWDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YKU7</accession>
    <name>A0AAD8YKU7_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_002471</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YKU7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="90"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1747127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="390" mass="43338" checksum="AB5FC71A95430960" modified="2024-05-29" version="1">MAWSKIDCELHDILCGGKKEGNLSLRHGQTDDNLPNDNEQEQGVGICCSWRCWTISNKYIPCSRVVLALSISAVGGDYSNLEEEDKVMSCAACGIAEDDDIELKTCTACKSVRYCSVTCQKEHRSKHKRACKKRAAELRDEILFKQPESSHLGDCPICCLPLPIDHTKSNMMPCCSKIICAGCEYANFVREQEAGLKHTCPFCRHPMAKSEEEANRTNVKRAESSNDPAAIHRMGARCYNEGDYESAFEYFYKAAGLGSVTGHYMLSTMYRNGPGGIKKDKKKELYHLEEASIGGHPTARNNLGCVEEENGRLDRAAKHWIIATKLGDDIALSSLRVRYTRGLVEKDDYASALRGHQAAVDATESPQRDKGEAYFKLGRDLIALGYGEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YL81</accession>
    <name>A0AAD8YL81_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MIP/aquaporin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_002559</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1747215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YL81"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019755">
        <property type="term" value="P:one-carbon compound transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034294">
        <property type="entry name" value="Aquaporin_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45665">
        <property type="entry name" value="AQUAPORIN-8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45665:SF9">
        <property type="entry name" value="AQUAPORIN-8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="115"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1747215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="160" mass="16293" checksum="1CBD9DA155D09761" modified="2024-05-29" version="1">MSVPEMITYWAAQLIGAIVGSLCGGIVTSSYTSVSIGTDATLTQALLAETVFTFILCFVILCVATNPKVESNHYYGLSIGLVIVAGAISVGGKYGGAFNPAVALGLSITSGMSKLFYALLVSAANLVGGIVAVGCFRVVLPSEFEAGGTVGETAPLRGYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YLY1</accession>
    <name>A0AAD8YLY1_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Glucose-6-phosphate isomerase</fullName>
            <ecNumber evidence="3 8">5.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_001897</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11816"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="EC" id="5.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the GPI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.9" evidence="3 8"/>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YLY1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048029">
        <property type="term" value="F:monosaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051156">
        <property type="term" value="P:glucose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05015">
        <property type="entry name" value="SIS_PGI_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05016">
        <property type="entry name" value="SIS_PGI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10490:FF:000031">
        <property type="entry name" value="Glucose-6-phosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10490:FF:000048">
        <property type="entry name" value="Glucose-6-phosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00473">
        <property type="entry name" value="G6P_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023096">
        <property type="entry name" value="G6P_Isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018189">
        <property type="entry name" value="Phosphoglucose_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035476">
        <property type="entry name" value="SIS_PGI_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035482">
        <property type="entry name" value="SIS_PGI_2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001211">
        <property type="entry name" value="PRK00179.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469:SF1">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00342">
        <property type="entry name" value="PGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00662">
        <property type="entry name" value="G6PISOMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SIS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00765">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00174">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="5 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6 8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="61"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="67"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1747934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="756" mass="85055" checksum="16636A37770FC78F" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMH0</accession>
    <name>A0AAD8YMH0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_001928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMH0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1747965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="217" mass="24475" checksum="5FC34F98A4CDD169" modified="2024-05-29" version="1">MDDDAMVPAPSCTGLSMTSLTDGVWTLFAGKQQNDNTPPSKEPEKSPTPKKKTRSVKFQYPVITKTHHRPMTEDEDVENLFFTEEEMEVLEEDRLATKFADDVEVLAEGQSWDAPIFQLSTSGSNLSIEEDYVPTKKPLPVKVGEVQNENGLSPRSKSIQALSILSERNSNKKRKKRDKKKRDACSNPVQEIVKPKIVQGVQIMLREKSSTNDMYLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YMH4</accession>
    <name>A0AAD8YMH4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">AP-4 complex subunit beta-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_001804</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YMH4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026739">
        <property type="entry name" value="AP_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015151">
        <property type="entry name" value="B-adaptin_app_sub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11134">
        <property type="entry name" value="ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09066">
        <property type="entry name" value="B2-adapt-app_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01020">
        <property type="entry name" value="B2-adapt-app_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Beta-adaptin appendage C-terminal subdomain" evidence="7">
        <location>
            <begin position="730"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1747841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="854" mass="92772" checksum="80902634CDCE8D37" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YN76</accession>
    <name>A0AAD8YN76_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_000309</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YN76"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1748370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="253" mass="28159" checksum="CE0E8127CBA1388A" modified="2024-05-29" version="1">MTSSIPRVGTSLLLRSKYIIPQHLLSHRCACLETVIYGHQRNENVSSRFYNAKRKHSTATSKLYQKILLPQHGQNGTLLLRSTSKSIGQVDIIPQWRDDTMLELVPIVMSEDMENSNDGNATNQNMSDDDLDVKEVQYDEESSSSAEHQTVTCGGLQFTLHRDGISTALGRKGSLVEVDVDVNASTAADNNEGIHHCRNGGSLLLLYPKNPILHATLPKEISMLLGVSWKVMPTLQHLMETSKFPSCVDMMLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8YPI4</accession>
    <name>A0AAD8YPI4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">tRNA nucleotidyltransferase/poly(A) polymerase family protein</fullName>
            <ecNumber evidence="8">2.7.7.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_000864</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.-" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8YPI4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052929">
        <property type="term" value="F:ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052927">
        <property type="term" value="F:CC tRNA cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001680">
        <property type="term" value="P:tRNA 3'-terminal CCA addition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05398">
        <property type="entry name" value="NT_ClassII-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3090.10">
        <property type="entry name" value="cca-adding enzyme, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032828">
        <property type="entry name" value="PolyA_RNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13734:SF5">
        <property type="entry name" value="CCA TRNA NUCLEOTIDYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13734">
        <property type="entry name" value="TRNA-NUCLEOTIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12627">
        <property type="entry name" value="PolyA_pol_RNAbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81891">
        <property type="entry name" value="Poly A polymerase C-terminal region-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly A polymerase head" evidence="6">
        <location>
            <begin position="320"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding" evidence="7">
        <location>
            <begin position="492"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1748925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="859" mass="95044" checksum="9B188A03E97A7BF9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D399</accession>
    <name>A0AAD9D399_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phosphoribosylaminoimidazole carboxylase</fullName>
            <ecNumber evidence="4">4.1.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">AIR carboxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">QTG54_017041</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + H(+) = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + CO2</text>
            <dbReference type="Rhea" id="RHEA:10792"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="EC" id="4.1.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (carboxylase route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.21" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000077">
        <property type="protein sequence ID" value="KAK1732266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D399"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004638">
        <property type="term" value="F:phosphoribosylaminoimidazole carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01929">
        <property type="entry name" value="PurE_classI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01928">
        <property type="entry name" value="PurK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016301">
        <property type="entry name" value="Ade2_fungi/plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003135">
        <property type="entry name" value="ATP-grasp_carboxylate-amine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033747">
        <property type="entry name" value="PurE_ClassI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000031">
        <property type="entry name" value="PurE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005875">
        <property type="entry name" value="PurK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040686">
        <property type="entry name" value="PurK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054350">
        <property type="entry name" value="PurT/PurK_preATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004679">
        <property type="entry name" value="PRK06019.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01162">
        <property type="entry name" value="purE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01161">
        <property type="entry name" value="purK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11609:SF5">
        <property type="entry name" value="PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11609">
        <property type="entry name" value="PURINE BIOSYNTHESIS PROTEIN 6/7, PUR6/7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00731">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02222">
        <property type="entry name" value="ATP-grasp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17769">
        <property type="entry name" value="PurK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22660">
        <property type="entry name" value="RS_preATP-grasp-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001340">
        <property type="entry name" value="AIR_carboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01001">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52255">
        <property type="entry name" value="N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="9 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="12">
        <location>
            <begin position="128"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1732266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="605" mass="63798" checksum="8A4FAEB224BFD2C8" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D578</accession>
    <name>A0AAD9D578_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Prolyl 4-hydroxylase alpha subunit-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_015839</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000049">
        <property type="protein sequence ID" value="KAK1733424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D578"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF229">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="6">
        <location>
            <begin position="236"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1733424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="404" mass="45098" checksum="3447C89A888C4A14" modified="2024-05-29" version="1">MMARYLHFRPPLEAALLFAIIVSAAVRVRAFHIPQSRPIHKVSLHASTTDSNNDDDDDLWNADISPLQQQRQRHNSEEQYDWTWSILPLPEHADNTSIAERARCAMMSSSTNNHHHHSNNKQPAALQDRCSVNLDAFHNGRCKAQWLHVDPPVLTVDNFLTEQECDDIRRITISPPPAGVGRVIKLESRLSESNKSNNQGTAVRLSTTWYVRYGAPQVAPLLRSLMQLLPDIQLEQTEEVQLVRYMGEGQGFGWHEDALSEQEATMDAGGQRIATLLVYLDDCQDGSGRTLFRDLRGGGKDGKQCRLGVSPKKGRALLFFPAISTTASIVEDDNTSTTDDDEDNGAFGNVYFDHTRADHRTTHAGEPPTGQNGQKHIAQLWIHSGIHTPVVFGRGLNRHSEAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5B7</accession>
    <name>A0AAD9D5B7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014524</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5B7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="282"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1734651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="408" mass="43891" checksum="F6CD62763F0EF811" modified="2024-05-29" version="1">MQGNMAQAPLPQSAQTTQQQQMQEQMNSSWSGDPSPGGARPATMARNVTEPAYMGMQQTYAPPPTLNDSGNSTFAPQQDRNNSGNSGNGGFQFQPSASFRLSDLSRMPVVGHGLEGAMEGETFDAFPRNSMVERGTLAGSAQAQSFHDSWGETNPAPLPYHTNPPEYNAFSAANQEHLLNCLEVDNGGANSAYAGGAGGDTSQERKRPSVKFQIEGRPSILHAKNIGYGFGDAASLTSHLDEMSIFDTHSLDSGMDAADREMEMELLGEFETGDSSLNFAPSSTDSRSSGSARQRPRRSILRHQSRYGTHNQNFAPVAAVTQRADPGMIFTSTFDTKPGGINSGTDISGLLGDRRKSAVAFEVQVERRRSSRMSIMSMFSRDAGSGMLSIQSADIRDLLEMDSDSDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5K5</accession>
    <name>A0AAD9D5K5_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5K5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01763">
        <property type="entry name" value="Ubl_SUMO_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="266" mass="29573" checksum="49AB39F3AAD7857C" modified="2024-05-29" version="1">MFNGSKVPPEATPDSLGMKGHATLSWEQTVFNGIHNIKSGKEVTALDMEGGVDNDMSSTIDIVFVDTSSSDEVLLRYVSYWKMKTLLSRYAAMREVPLKSLRFKCNNRMLFVSSIGNKSPYDLGIQNNDVVYASLLGNVDVKLDEAGTTKKSGRSQRSTRAAKGKTKSNSKKKASCQPTYSTIDDEERLRRAHSKMLSRVFDEANPQFKKIRQKLNSLALKQTPPKSKSSSPRARVKESKTDMSDISSFSLDNKAIKTRSISSLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D5L6</accession>
    <name>A0AAD9D5L6_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Leucine-rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_015495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000044">
        <property type="protein sequence ID" value="KAK1733798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D5L6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1733798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="295" mass="33166" checksum="09B9B05C7167BEEB" modified="2024-05-29" version="1">MMAADGWHIYYGNGEIIPPGVTRVRIHESVTVIPAEAFYENLDIKELDCHDRVKTVEEEAFYCCFSLKRVIMRGVKVVQQCAFAECDALADVECDKLEIIERGAFESCQSLKSINLPSAKIVGSFAFSYCKALTNVIFGKALESIGRAFRDCTSLERITIPLEEGIITADNTFQRCKKLKHVDLVEEAVLSDTIAALLSEEWKNDMDREIEAINQILPNTLAGNWENNEDVGGKALVIRMWIASVLHKIVHYKAQHRSYLNEAATTLQLALPNDIVNMNVLPFLELPSYTFEGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D705</accession>
    <name>A0AAD9D705_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_014275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000035">
        <property type="protein sequence ID" value="KAK1735209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D705"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1735209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="577" mass="64174" checksum="293A669F4367F4C9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D762</accession>
    <name>A0AAD9D762_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L30</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_013037</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000029">
        <property type="protein sequence ID" value="KAK1736437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D762"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000001">
        <property type="entry name" value="60S ribosomal protein L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039109">
        <property type="entry name" value="Ribosomal_eL30-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022991">
        <property type="entry name" value="Ribosomal_eL30_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002172">
        <property type="entry name" value="PRK01018.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11449">
        <property type="entry name" value="RIBOSOMAL PROTEIN L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00709">
        <property type="entry name" value="RIBOSOMAL_L30E_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00993">
        <property type="entry name" value="RIBOSOMAL_L30E_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="4">
        <location>
            <begin position="14"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1736437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="110" mass="11917" checksum="EDCAFBB575C19E73" modified="2024-05-29" version="1">MAPSKKNQKKNVESMNSRLKLVMKSGKAILGYKSGLKGLRTGKSKMVLIASNCPPLRKSEVEYLAMLAKVQVHHYSGDNTDLGTACGKMFNCSVVTIIDGGDSDILVKQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7L6</accession>
    <name>A0AAD9D7L6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Condensin complex subunit 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_013530</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CND3 (condensin subunit 3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000032">
        <property type="protein sequence ID" value="KAK1735824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7L6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000793">
        <property type="term" value="C:condensed chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027165">
        <property type="entry name" value="CND3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025977">
        <property type="entry name" value="Cnd3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14418:SF5">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14418">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12719">
        <property type="entry name" value="Cnd3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nuclear condensin complex subunit 3 C-terminal" evidence="9">
        <location>
            <begin position="597"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="853"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="979"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="875"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="990"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1006"/>
            <end position="1016"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1735824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1077" mass="118289" checksum="A97BBFCD66164B29" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D7T9</accession>
    <name>A0AAD9D7T9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">WRKY19-like zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011697</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D7T9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056866">
        <property type="entry name" value="Znf_WRKY19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24906">
        <property type="entry name" value="Zf_WRKY19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WRKY19-like zinc finger" evidence="1">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="277" mass="29081" checksum="865E1E8D7DB3CCC3" modified="2024-05-29" version="1">MNIIHVNSACSTSAEPTSYDDTDEVKVCSADGCTNQSFKGGVCQRHGAKVPRCRTKGCPNGAVQGGVCVRHGAQTKRCSHDGCTNRAYTGGVCVRHGAKVRLCSFPECTNQVKMRGVCIKHGAKIKGCSFEGCTKHSQEGGVCFEHGAQGKLCSSGGCTKRAKARGLCYKHGTKRYTCSTEGCTKLSIQGGVCVRHGAQGRPPCSVEGCTNKSVNKGVCQRHGAKIKRCRMKGCTNQVVKGGVCRRHGAKQECAAGGCTNHAKSGGVCIRHVATVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D803</accession>
    <name>A0AAD9D803_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fasciclin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_011698</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D803"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF77">
        <property type="entry name" value="FI19380P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="149"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1737412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="162" mass="17291" checksum="4DB52AB41B53A45F" modified="2024-05-29" version="1" fragment="single">FFTLCSYLEITGLYGKLNSSGTSTLFAPNNDAFEKLANVVDLADDEIMGLLMYHVAPNILTYNNLMMIAPGVVESMVPALPIAVSTGADGDVLLNGNVKITTPDIEASNGIIQVIDQVIIPPINPPTRPAPVTPEPTLMGKSSKHSSKSSKYSSMSNMSYKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D961</accession>
    <name>A0AAD9D961_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aryl hydrocarbon receptor interacting protein-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_012160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000026">
        <property type="protein sequence ID" value="KAK1737293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D961"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050754">
        <property type="entry name" value="FKBP4/5/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46512">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="352"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="380" mass="43548" checksum="A102C4B759176055" modified="2024-05-29" version="1">MDKIDIDGTPFSVLLDRAVKIKSSQSAHLAQKYNALPDFVQSSLFPSDEVINARNLCSFTERFDAAMAWKEDGNAAYREGRFDVALEKYKMSLTLFRYVENSNPNIKNEGIKDEYLREIMYVPKNNDEEQQLHQFLVKLYNNLALTSLKRNDHRTAIQACDCAIKVDRQNDKSFYLRAQARIAPKSASAIDEELAMMDLRAAVTINPHNKQARKQLQEARLRIRSQRTLDKNAFAGLFNRGEVYDTNELDEEKDARRKCLENDRIKVKEESLKSRDQVVNKVDFRNPTEKMLASADAMGVDLSDPQTIEMLEQMQKEKNGGAEVCYDSIEEQQTISTAEIPNKYSSTRLFKLVRGATMLCVALIVYIRLLNSFVQNQMNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9A9</accession>
    <name>A0AAD9D9A9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_010153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1738837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9A9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1738837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="497" mass="56161" checksum="D500060E1842D221" modified="2024-05-29" version="1">MTTKASRLCVICTNDYGGRIVPAMLTCCMNHVCYDCAESDRSRKITDLEGNRKLIRCIFCNQKYHCSKETPWKVNNHFIEESGIDVDLTFVRETQAAMTAGVTNNQRKGPRCRPDTSSLNNAADNSNVVRQNVTRSSGRGDGEDGEDTEVKLIDLSNNQDSPSIALTNRDAGTNLRRSQRTRRPTERNLADEMQSSNDDITTNTRQSKRSRIVEREVAGDTIERAIENRRVTNIDDERYHQGANSTVSDEAGDQQWREVIAKDNADVYRIRCYNNDSKTEGDKFSRRISEWCVKNGIMITELELAKLLPRCQWFDGEALKMKVASIDSNQELRHICDECKDFNPKERTYIGSYRQFVEMKKGDIIVLHTKGGYAKGGPPQTLSFGVIEDDSLTTMTKEEATQRQCPLDLSGLCDSNSPGGPAARIGFMAKKVKWLRQGELKAVRGPRQVSWLVEASPLWLMKVGTLDQNILRNAISKMGSEQFMRNTHSIDNQWTMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9F0</accession>
    <name>A0AAD9D9F0_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_011849</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000025">
        <property type="protein sequence ID" value="KAK1737563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9F0"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1737563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="83" mass="9296" checksum="E2444F4DF38B1A3A" modified="2024-05-29" version="1">MSPEQLTDEVASLRRKYDELVAFSVNLTAERDILNNTLEQTKRDLNREMATRTALEKQGLKVGSRSQDSRSNKSSGGVSARHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D9T7</accession>
    <name>A0AAD9D9T7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">N-acetyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_011337</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="4"/>
    <dbReference type="EMBL" id="JATAAI010000022">
        <property type="protein sequence ID" value="KAK1738043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D9T7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031416">
        <property type="term" value="C:NatB complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004596">
        <property type="term" value="F:protein-N-terminal amino-acid acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051646">
        <property type="entry name" value="NatB_acetyltransferase_subunit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45910">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45910:SF1">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="2"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1738043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="167" mass="19480" checksum="030D1215CE68A53F" modified="2024-05-29" version="1">MTSTRQFHMNDLFRFNNVNLDVLTETYNMPFYLQYMSKWPELFTVAEAPDNSIMGYMLGKSEGSDTLWHGHVSAVTVAPLYRRLGLAKTLMEDLENTSSNVYNAFFVDLFVRASNTLAINMYEKFGYVLLWDDPEDAWDMRKALARDEKKQSVIPMDRPVLPQELEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DA98</accession>
    <name>A0AAD9DA98_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tetrahydrofolate synthase</fullName>
            <ecNumber evidence="3">6.3.2.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Folylpoly-gamma-glutamate synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Tetrahydrofolylpolyglutamate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_010538</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + L-glutamate + ATP = (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n+1) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10580"/>
            <dbReference type="Rhea" id="RHEA-COMP:14738"/>
            <dbReference type="Rhea" id="RHEA-COMP:14740"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:141005"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolylpolyglutamate biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the folylpolyglutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.17" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000020">
        <property type="protein sequence ID" value="KAK1738508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DA98"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="entry name" value="Mur ligase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="entry name" value="Mur-like, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136:SF5">
        <property type="entry name" value="FOLYLPOLYGLUTAMATE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="FOLYLPOLYGLUTAMATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="MurD-like peptide ligases, catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="MurD-like peptide ligases, peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01011">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1738508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="678" mass="75777" checksum="5317D0F84DCE3622" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DAY6</accession>
    <name>A0AAD9DAY6_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mpv17/PMP22 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">QTG54_010409</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R05AC</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000019">
        <property type="protein sequence ID" value="KAK1739093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DAY6"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF80">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1739093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="248" mass="27633" checksum="A9F7E30A678B8DCB" modified="2024-05-29" version="1">MSMMGCRMPSQSLHKLSNLRLASKRSSSGGSSSPSILRNPLQWYVAKLDTHPITTKCISSGLISGSGDLLCQSIIAKRKQQSTSHELDWMRTLRFTLLGSFLVAPTVHSWYGMLMSRIPGTSLAAIGKRLFFDQGLFAPLFTPTFISMLTVLEHLSSPLDQVVEKEGVNNNDSNNHNNSDLLTHLRDRLKNDAPDAILVGWSIWVPSMAVMFAFVPGKFQVLYSNGVGFVWNAYLSWKTHEGEEERTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DBH3</accession>
    <name>A0AAD9DBH3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_009454</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000017">
        <property type="protein sequence ID" value="KAK1739695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DBH3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="189"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="824"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="46"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="338"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="604"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="8"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="189"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="215"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="824"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="861"/>
            <end position="871"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1739695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="901" mass="104343" checksum="68C65FCA150F305B" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCQ3</accession>
    <name>A0AAD9DCQ3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Adenosine deaminase</fullName>
            <ecNumber evidence="8">3.5.4.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">QTG54_008386</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; purine nucleoside salvage.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.4" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000014">
        <property type="protein sequence ID" value="KAK1741134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCQ3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019239">
        <property type="term" value="F:deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016814">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43114">
        <property type="entry name" value="ADENINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43114:SF6">
        <property type="entry name" value="ADENINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Adenosine deaminase" evidence="7">
        <location>
            <begin position="55"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Adenosine deaminase" evidence="7">
        <location>
            <begin position="362"/>
            <end position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1741134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="662" mass="71547" checksum="46379E9A70B5D7BB" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCQ5</accession>
    <name>A0AAD9DCQ5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_006378</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCQ5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042285450" evidence="1">
        <location>
            <begin position="20"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1742781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="219" mass="23915" checksum="14E9F528A30CE063" modified="2024-05-29" version="1">MITTYILLCCFLCLRSSLAFAPHAHLFSNQVDAPSTTTLKCAPESHDGNCNRRSFVGNALTSAGFLVANPSTSHAVMDPSKNTKGTLKELSMEEAEERFRAGRATVDYLLNNYNEVCDGGGDNVRRYLGTVGTQSGLFGISKAMKTLADKADDIVEYTELSREIEQCIEQADGSAYMAIFVTTSTSYTPPEKYFGDAKIEVKRLAKSMDELAVMLGITF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCS7</accession>
    <name>A0AAD9DCS7_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">QTG54_006274</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCS7"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053139">
        <property type="entry name" value="Surface_bspA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661:SF3">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45661">
        <property type="entry name" value="SURFACE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1742677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="240" mass="27092" checksum="EE07E04887138D0F" modified="2024-05-29" version="1" fragment="single">MAEAQEADGIFIYMGGDQVVPYDVVRVRIDKSVTIIPERAFDNRGYLIYVEFHDGIEIVEHRAFNCCYSLRSAKLLGVKVIEGGVFHFCRGLTEVEFGVELETIGEGAFYSCTSLRTIKMPSVRSIGRYAFDNCQQLTDLDLPEGLETVGQRAFHFCQRLRRIAVPLRSDMIANNVFSDCPDLTTMDLVGGIHNTIASLHLESWKNDTTEEINRINQVLPNTTSSQKTAEIQQWMRSVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DCT8</accession>
    <name>A0AAD9DCT8_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">indole-3-glycerol-phosphate synthase</fullName>
            <ecNumber evidence="3">4.1.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">QTG54_006483</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:23476"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="EC" id="4.1.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.48" evidence="3"/>
    <dbReference type="EMBL" id="JATAAI010000010">
        <property type="protein sequence ID" value="KAK1742886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DCT8"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004425">
        <property type="term" value="F:indole-3-glycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004640">
        <property type="term" value="F:phosphoribosylanthranilate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000503">
        <property type="entry name" value="Indole-3-glycerol-phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045186">
        <property type="entry name" value="Indole-3-glycerol_P_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013798">
        <property type="entry name" value="Indole-3-glycerol_P_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22854:SF2">
        <property type="entry name" value="INDOLE-3-GLYCEROL-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22854">
        <property type="entry name" value="TRYPTOPHAN BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00218">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042017609" description="indole-3-glycerol-phosphate synthase" evidence="9">
        <location>
            <begin position="30"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="Indole-3-glycerol phosphate synthase" evidence="10">
        <location>
            <begin position="107"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1742886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="375" mass="39637" checksum="36F27CB0D8467BAA" modified="2024-05-29" version="1">MTPLRIHRLPTAIAAIALLTTLSVDPSSAFAPGANNKSPIQSLPTRSQTANTIFTTSTSLNALGVFVRKAKEADVRKYCQDGPPESVLSLLQKIKDSSDKDDEVELPTELQTLLTKRKGTITIIAEYKRKLEGSGFITDVLDPVLLSPVFREFGAAAVAVLADERTGGCTYDDIVAVVEEQDEALGDVPGPLPVISSDLIVDEIQIAQAADSGAKAVTVTYGVVGEEKVQQFIKDAASLGLEVIVNVGTAEEAQGAVNAGASIISVTGVDGSDNKFAVIESLSIPEGRNVCTIANILAKDNKALEEVEEAWMCRDAGFNCVWVSDALYKAGNDPVEHPGAIISTMKAKSSVKYASPKARSGKGEGAREYLGDILM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DEF1</accession>
    <name>A0AAD9DEF1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_005174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DEF1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1744641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="269" mass="29214" checksum="14FE3BC438092606" modified="2024-05-29" version="1">MAPPCPCSMNDSLARKSSDSSSSESAVVPDESGCGSCIINFLHLRPHAVDAVVDDNTKKQDADNMMTDADMIMIDASMSEDHDVGSNDMKKPPPSVCQAVGTRPRYPSPLPNDGDSRKPSPTTPPPLPQRRGDGFDIITNEPPSAESISAELHHTSTLSIPTLLRFPHASLLPQSPNLISTTNNDGAPLLSLSSMSMNLANPNEAMMPHIPRINLQMRHSNEASYRRGTDSHRNRLHATQQTMEARQSIGGFVPIQQDSIEEEEDGEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFU4</accession>
    <name>A0AAD9DFU4_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_004818</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFU4"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="522"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="826" mass="92178" checksum="2DA9505E1BFB5558" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DFX5</accession>
    <name>A0AAD9DFX5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002853</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DFX5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31827:SF1">
        <property type="entry name" value="EMB|CAB89363.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="434" mass="46706" checksum="6A7D4E80617016EC" modified="2024-05-29" version="1">MNNEEVEQCVVIAGEEDPFLSGGDEEQGNKRKHSGEEEEDEAGDEEGPDQKKRKSGGYAVQRGLCVAHGAVVKKYPRKRCVVEGCDNIARGKMAKCVGHGGTPCNKFAQRGGTCIKHGKELAAARAQAAAIENGAAVAAPPPVAVAPPPAIPPAAVAPPPAIPPVAALPPFDVNNDNDDTENAELSQILCSEIVNDQDSLVSSVDNNNNGVMEDSNVEPPSVAVAAMPETVTTTNKISKKKRARKRCIVEGCNKIGRGKSAKCVAHGGTPVKKCSFEGCQNNQKQGGRCKRHGAKLNEKPKICIFLIAIIYIGPNLPGAREYKIARKDDGDAAVVDYVCMLITSYIAFRWLDVKRAKCSLILFLSHRYLPLVASMITQAQIFSIRDLISIPDEVDGREKKKTLPSGKDPNWSSLVMTPKEVCNKESTICDWFGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG66</accession>
    <name>A0AAD9DG66_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mg-protoporphyrin IX chelatase</fullName>
            <ecNumber evidence="9">6.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">QTG54_003123</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>protoporphyrin IX + Mg(2+) + ATP + H2O = Mg-protoporphyrin IX + ADP + phosphate + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13961"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:60492"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.6.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Porphyrin-containing compound metabolism; chlorophyll biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Plastid</location>
            <location evidence="9">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Mg-chelatase subunits D/I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.6.1.1" evidence="9"/>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DG66"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016851">
        <property type="term" value="F:magnesium chelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01451">
        <property type="entry name" value="vWA_Magnesium_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.80">
        <property type="entry name" value="Magnesium chelatase subunit I, C-Terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041702">
        <property type="entry name" value="BchD/ChlD_VWA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011776">
        <property type="entry name" value="Mg_chelatase_ATPase-dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000523">
        <property type="entry name" value="Mg_chelatse_chII-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02031">
        <property type="entry name" value="BchD-ChlD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43473">
        <property type="entry name" value="MAGNESIUM-CHELATASE SUBUNIT CHLD, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43473:SF2">
        <property type="entry name" value="MAGNESIUM-CHELATASE SUBUNIT CHLD, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01078">
        <property type="entry name" value="Mg_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0149">Chlorophyll biosynthesis</keyword>
    <keyword evidence="9" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4 9 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 9" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="9" id="KW-0934">Plastid</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="11">
        <location>
            <begin position="575"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="407"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="419"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="433"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1746516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="783" mass="83844" checksum="6EE14C7752FE0C36" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DG91</accession>
    <name>A0AAD9DG91_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6824 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_005041</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DG91"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049227">
        <property type="entry name" value="DUF6824"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20710">
        <property type="entry name" value="DUF6824"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6824" evidence="2">
        <location>
            <begin position="25"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="432"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1744508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="468" mass="51286" checksum="78BFAF66042D2B41" modified="2024-05-29" version="1">MADQISSSSAKQELLEGITQPHANDVLSGRGNFVNHHSGNENFRALVKHHKKAYVACPKNQKAIYSKLIYDEIRSMNPPGRFLKQDAKTKLWSDVGEKKALDKTRQALREGAPDLMKELDGTDTNSAEYKFENQDALGPLRAARQNNPLTLSLGSFSLNSLDPQRGTEPVSTPPLPGIPGQIQMNNPGLTQEGANALLAAATHMQLQQQQQQQQQQLQFLQQQAGNINPAQLQLLQNHLQMNQQQQQQQPNPVFSGGNNIFLGNNGGYDAALAAAQASSNMGSEQVAALLNAIHNHAANNSADVLQQQLTQQLLTQNLLNQMNNSSNTLQAGNTNQNIQHGFHLPQNAAQHEDSTVSANAMGTSSRARAQRIGLKNSFTQQRRPNRNLKNNEQALMGNSLMSVESINMDQLRMSGVSLGEFTGSEMCKLFESDRELGKAKDKTDDVSEVSDAMSEDAMSEDEKETSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DH15</accession>
    <name>A0AAD9DH15_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA (guanine(46)-N(7))-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">QTG54_003454</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R05AC</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42708"/>
            <dbReference type="Rhea" id="RHEA-COMP:10188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10189"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.33"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.33" evidence="2"/>
    <dbReference type="EMBL" id="JATAAI010000005">
        <property type="protein sequence ID" value="KAK1745530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DH15"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043527">
        <property type="term" value="C:tRNA methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008176">
        <property type="term" value="F:tRNA (guanine(46)-N7)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003358">
        <property type="entry name" value="tRNA_(Gua-N-7)_MeTrfase_Trmb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417">
        <property type="entry name" value="3-DEOXY-D-MANNO-OCTULOSONIC-ACID TRANSFERASE/TRNA GUANINE-N 7 - -METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417:SF21">
        <property type="entry name" value="TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02390">
        <property type="entry name" value="Methyltransf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51625">
        <property type="entry name" value="SAM_MT_TRMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042047300" description="tRNA (guanine(46)-N(7))-methyltransferase" evidence="8">
        <location>
            <begin position="29"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="104"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="115"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1745530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="435" mass="48309" checksum="506D14BB2D5FB9BB" modified="2024-05-29" version="1">MAAYSMLSVQMALFLALSCTSITHKAASFTFNRGITSLATTRVASKTARYAVTKEAVEIWRQKAGFGTVKVQDNISNDTTSSNNEASTTLITAATAAADIANEEHQAKAAQAVQTDDDSSSAEVEEEEEERYMPPWSLATQRAPSSKAFSRFRQHVNPLSRRFQMPTDLPENWPYSDFTNVNLPLYLDIGCGKGGFLLELVGRRHGNDYPDGTDTYMNNTRLFTDTTDEWLPSTMNYLGLEIRPGVSQYAQNRVEKRGLSGKLSFVGCNANVDLDRLLSLYTESAETEVVDDGAIGDGGSNNELKFVSIQFPDPHFKKSHTKRRVVTPALVTTLAKFMNQGGVVFLQSDIKEALEAMREKFVEDDGLVYFDEHCDDDDCKIDDGTEEEYGLANPLGIPTEREVSVLNQDLPIYRTLFLRNDVSYPSKSSDLARNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DI69</accession>
    <name>A0AAD9DI69_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">WD40 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_003095</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000004">
        <property type="protein sequence ID" value="KAK1746488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DI69"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027145">
        <property type="entry name" value="PWP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19858:SF0">
        <property type="entry name" value="PERIODIC TRYPTOPHAN PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19858">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="156"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="358"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="470"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="472"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1746488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="648" mass="71549" checksum="9FC08107C9C4DCEB" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIF3</accession>
    <name>A0AAD9DIF3_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_000960</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIF3"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042048597" evidence="3">
        <location>
            <begin position="22"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="437"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="478"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="519"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="558"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1749021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="619" mass="66266" checksum="57491049207F47B7" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DIK9</accession>
    <name>A0AAD9DIK9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_002237</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000003">
        <property type="protein sequence ID" value="KAK1746893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DIK9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1746893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="277" mass="30702" checksum="691372ED43B95CF7" modified="2024-05-29" version="1" fragment="single">TLVGLYSDGDNGISNLNTAAATGAFRRATASYDKLSVNSTICRATYSSLTQNHYAAASENIVNHRADIILLPQNTYKQQFAWFSDASSSSGIPPIDVTVTKSNQITEEEILELQSELRTHHRHAAYSAALETATELLERCTSHFGRMHPATASAYNNVGLMNKLLGNYVEAKNCWKGHSSYAAPLSNLGMLERSRVLESEAEEGEDDNDASGQNEDDNDVELETLRDSNNPEEKTKLSALERMQLNESAIEYFDEAYRIVFRSWGPIIHTLFRVGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJ01</accession>
    <name>A0AAD9DJ01_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Malic enzyme (NAD-dependent)</fullName>
            <ecNumber evidence="10">1.1.1.38</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_000946</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="7">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="7">Divalent metal cations. Prefers magnesium or manganese.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the malic enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.38" evidence="10"/>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1749007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJ01"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004471">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05312">
        <property type="entry name" value="NAD_bind_1_malic_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000182">
        <property type="entry name" value="NAD-dependent malic enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="entry name" value="Malic enzyme, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001891">
        <property type="entry name" value="Malic_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010052">
        <property type="entry name" value="PRK13529.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406">
        <property type="entry name" value="MALIC ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406:SF32">
        <property type="entry name" value="NADP-DEPENDENT MALIC ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000106">
        <property type="entry name" value="ME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00072">
        <property type="entry name" value="MALOXRDTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Malic enzyme N-terminal" evidence="9">
        <location>
            <begin position="164"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Malic enzyme NAD-binding" evidence="8">
        <location>
            <begin position="354"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="258"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="353"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="496"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="541"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1749007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="647" mass="71733" checksum="B6A2D09505C574DF" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJ26</accession>
    <name>A0AAD9DJ26_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">WD40 repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001321</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJ26"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879:SF9">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="51"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="25"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="450" mass="49183" checksum="58F86CF04396BA94" modified="2024-05-29" version="1">MADEHPHKIRPQAFHEANALHSSFFGEPLPSSSVNTAPSSPRRPQNERMCMGGHRDPIYGTAFSPDGKYLATASEDSTVRIWLVQSHKLVATLSEGMDTNYECLRVAWMKITNDNDSNLQQNDGGVEKYVLASGGADGVVRLWSAVENEEQKLEWQCVGSLNHFVEDDEERPQIYALQFIQSPSYPNIDIMLTSAHDSVYLWTIENDNEESSSESPNARQKKFLSLSSIQFSHLDDASQTYQFGGPRNPENDLYVFDASYSESNDLLAAALSDGTCRVLSLAASSVDEDESVQREQCVLSLPPGYFGGRGGHLTAVEWDSSGTRLATCIASGRVILWYLQNVGTGNSISLRPSVVSILDGGSGRQVFGAKYCCGKNEDLLLTWGIEGKVSVWDSYSVGEVMSPICTLISHTEYPIFALDVTQTGAKQSIAVGGGKEGGLFLGVPAYLYDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJ35</accession>
    <name>A0AAD9DJ35_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001982</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1748019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJ35"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042029969" evidence="2">
        <location>
            <begin position="26"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1748019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="352" mass="38207" checksum="82DA070247B5751C" modified="2024-05-29" version="1">MSFNNCRLQLVLCLVAFSLAVVVNGFQQLSLPRSSARPMSKQQTSSSLHMGFFDNILKDAFSNDESLSRDGVKGSIEGPEDTMNENFGIAAQQPEQTEVQKRWIESQLQQKQQEVQQRRQQQAVASPALVKTAKGAPLTNQVLSDTTWELGLYLTGVPDRDPSNDLYGSKSNVSVRDRQLGLGVSLPNEPTAKIQIQLLEDGSVAICGSATDSDDEECQVDEVCSTDVPGQWKLSDDGKTVRIGIPMRGYRRTITTTGTIQNVFWSQGEEATSKTSSTYSIPEGFVFGDISVGYGDEPGKLIMMDEKSTSPSTGMSVIPGGLLRVEKKNGLLGASSTLVPCGRFSGRMTCTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJC9</accession>
    <name>A0AAD9DJC9_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_001606</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000002">
        <property type="protein sequence ID" value="KAK1747643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJC9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="215"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="254"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1747643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="487" mass="54824" checksum="C65F335071D15D92" modified="2024-05-29" version="1">MPSTVGRRLMQKNMRKAAKAREKDNMSGGDEFEDDPATEADEGNYTYPDHLDDDDDEKEDQPTGRSIFGRGGRKITERASSFGDPGFNKSDTTLKALSDPQSELARFLLTKRGDDMKWKSMRSIENRAAIFGKDSSMVKGMRSNLVWFYSMSLEPLDVRKERIIMLAEAYAIFGALFLSGTWVLYEWGSSLGYGGCSLDDSFACHPGLDRAFEAIMTMAITSNLFMAMFASFLWLMSVLFSGTHQNWVFGCRHLLVICHTLLCCVLVLTIAGVGVGILTKLAPNWPELVIAMAFFLIIAVCGVYQSSVLIATQLPLEYYHFPLWFKWGILPFPMLTKKSRDKIRAGAHQRAKELKARAFKERTVLDPSVSLKDSFSPIGRLLRAAADNIGKKDHDISQYEARLEKDWYTKTEELKSMTVDILARYMPRRMADEVHRTLTLELDSPTLNEAGGLISVSIGRGEVDDDDNGEKRVSWKIDLSDAQMRDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9DJS1</accession>
    <name>A0AAD9DJS1_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">QTG54_000244</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000001">
        <property type="protein sequence ID" value="KAK1748305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9DJS1"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="708"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1142"/>
            <end position="1205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="65"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="727"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1161"/>
            <end position="1174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1748305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1205" mass="135064" checksum="0CC6F26F2F486D02" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2PZR2</accession>
    <name>A0A7S2PZR2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">QTG54_004929</name>
        <name evidence="3" type="ORF">SMAR0320_LOCUS20902</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R05AC</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="HBGZ01029403">
        <property type="protein sequence ID" value="CAD9626657.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000007">
        <property type="protein sequence ID" value="KAK1744396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S2PZR2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="61"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="139"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CAD9626657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1744396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="176" mass="19908" checksum="EE0FFDEB99FCC4B6" modified="2021-06-02" version="1">MVNILKSRQPKQAKPTGVKFADAGNTKKAKGGIRRTKKASSYDKENGLGAVPLAKGRSDIYTKLRKQIELLETDTQEAQRKIEELEMEEEKLLLGSHAKLIELDQKFANVEESLKHEIVRLQADFHMQQLVIDEKNVEIADKNDELMLKDKEIEELKAKVIKANDKLTAAAKSLAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-06-02" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A7S2VHQ5</accession>
    <name>A0A7S2VHQ5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">V-type proton ATPase subunit D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">QTG54_004144</name>
        <name evidence="5" type="ORF">SMAR0320_LOCUS23776</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Corre E."/>
                <person name="Pelletier E."/>
                <person name="Niang G."/>
                <person name="Scheremetjew M."/>
                <person name="Finn R."/>
                <person name="Kale V."/>
                <person name="Holt S."/>
                <person name="Cochrane G."/>
                <person name="Meng A."/>
                <person name="Brown T."/>
                <person name="Cohen L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">SM1012Den-03</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R05AC</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the V-ATPase D subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="HBGZ01033208">
        <property type="protein sequence ID" value="CAD9632163.1"/>
        <property type="molecule type" value="Transcribed_RNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JATAAI010000006">
        <property type="protein sequence ID" value="KAK1744853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A7S2VHQ5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.3240:FF:000026">
        <property type="entry name" value="V-type h-atpase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002699">
        <property type="entry name" value="V_ATPase_D"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00309">
        <property type="entry name" value="V_ATPase_subD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11671">
        <property type="entry name" value="V-TYPE ATP SYNTHASE SUBUNIT D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01813">
        <property type="entry name" value="ATP-synt_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="208"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="208"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CAD9632163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1744853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="241" mass="26724" checksum="ECFDADDCFB2E713C" modified="2021-06-02" version="1">MSEVPPTRMNQQVFKAKKKAAESGHRLLKKKADALKVKFRDYAKAIAETKSSMAADSSSAFFSLTQAEYAAGNFKQKVSEGSMTARVRVGAGIDNVAGVKLPVFSYFETGAATDNASLGLVGGGKKIQMVREKYTVLLQNLIKLASLQTSFVTLDEAMKVTNRRVNALENVTIPKIQGVLDYIDRELDELEREDFTRLKLVQGKKEVQEEQQRKMMKEAEGHNDEDIMGTFDAGDDEDVVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2024-10-02" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRU8</accession>
    <name>A0AAD8XRU8_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_016946</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000069">
        <property type="protein sequence ID" value="KAK1732367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="927"/>
            <end position="961"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1732367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="1381" mass="153466" checksum="98892BFAD2836225" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XST2</accession>
    <name>A0AAD8XST2_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA sliding clamp PCNA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">QTG54_016314</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processivity during elongation of the leading strand.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the PCNA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000055">
        <property type="protein sequence ID" value="KAK1732983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XST2"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043626">
        <property type="term" value="C:PCNA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030337">
        <property type="term" value="F:DNA polymerase processivity factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006272">
        <property type="term" value="P:leading strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006275">
        <property type="term" value="P:regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019985">
        <property type="term" value="P:translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00577">
        <property type="entry name" value="PCNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.150.10:FF:000006">
        <property type="entry name" value="Proliferating cell nuclear antigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.150.10:FF:000008">
        <property type="entry name" value="Proliferating cell nuclear antigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.70.10.10:FF:000001">
        <property type="entry name" value="Proliferating cell nuclear antigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.150.10">
        <property type="entry name" value="DNA Polymerase III, subunit A, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00317">
        <property type="entry name" value="DNApol_clamp_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046938">
        <property type="entry name" value="DNA_clamp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000730">
        <property type="entry name" value="Pr_cel_nuc_antig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022649">
        <property type="entry name" value="Pr_cel_nuc_antig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022648">
        <property type="entry name" value="Pr_cel_nuc_antig_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00590">
        <property type="entry name" value="pcna"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11352">
        <property type="entry name" value="PROLIFERATING CELL NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11352:SF0">
        <property type="entry name" value="PROLIFERATING CELL NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02747">
        <property type="entry name" value="PCNA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00705">
        <property type="entry name" value="PCNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00339">
        <property type="entry name" value="PCNACYCLIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55979">
        <property type="entry name" value="DNA clamp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proliferating cell nuclear antigen PCNA N-terminal" evidence="8">
        <location>
            <begin position="60"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Proliferating cell nuclear antigen PCNA C-terminal" evidence="9">
        <location>
            <begin position="186"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1732983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="319" mass="35619" checksum="E047A3FEB8812C7C" modified="2024-05-29" version="1">MMMMPTIDEQRANHRRIFSLKYGAGKEGKPDIFGATALHLLSKNHKKSFTPTHHQTTPTMFEARLTQGKVFKQLIEALKDLVQEANIDCSDDEISIQAMDNSHVSLVAVSLRSGGFDHFRCDRPISLGFNAANMGKILKCAGNDDIITLKAEDEGDALTMMFESPNGDRIADFELKLMDIDSEQLGIPETDYKCTIQMPSGEFQRIIRDMQVLGDTATISCTKEGVRFSVSGDLGTGNVLVRQNSTHEKEEERVMIEMEEPVELTFALRYLNFFTKATSLGGTVILSMSPEVPVVVEYPIGETGYIKYYLAPKIDEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XUC5</accession>
    <name>A0AAD8XUC5_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Death-specific protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_015404</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XUC5"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042025302" evidence="2">
        <location>
            <begin position="23"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1733877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="120" mass="12948" checksum="CD1AE68337BFDD8D" modified="2024-05-29" version="1">MMNNKQTLLAIMALAAAHSSSAFVVNTQARAISYRPLSYSTGDTMTNDYTDVTATTSEQSSKLIMDIPPTPVAPKNKPAPKKKANAAHKEGVFSHRHGCRHPSRPRSAQQSTSKGNHTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XV18</accession>
    <name>A0AAD8XV18_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">QTG54_015480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R05AC</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JATAAI010000043">
        <property type="protein sequence ID" value="KAK1733953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XV18"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="661"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="684"/>
            <end position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1733953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="765" mass="81296" checksum="A7473E27D94F8CB9" modified="2024-05-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVM9</accession>
    <name>A0AAD8XVM9_9STRA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">tRNA-specific adenosine deaminase 1</fullName>
            <ecNumber evidence="8">3.5.4.34</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">tRNA-specific adenosine-37 deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">QTG54_014579</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
                <person name="Kourtchenko O."/>
                <person name="Robertson E.K."/>
                <person name="Larsson T."/>
                <person name="Maumus F."/>
                <person name="Osuna-Cruz C.M."/>
                <person name="Vancaester E."/>
                <person name="Stenow R."/>
                <person name="Vandepoele K."/>
                <person name="Ploug H."/>
                <person name="Bruchert V."/>
                <person name="Godhe A."/>
                <person name="Topel M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R05AC</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically deaminates adenosine-37 to inosine in tRNA-Ala.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>adenosine(37) in tRNA(Ala) + H2O + H(+) = inosine(37) in tRNA(Ala) + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:50968"/>
            <dbReference type="Rhea" id="RHEA-COMP:12855"/>
            <dbReference type="Rhea" id="RHEA-COMP:12856"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:82852"/>
            <dbReference type="EC" id="3.5.4.34"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>1D-myo-inositol hexakisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the ADAT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.34" evidence="8"/>
    <dbReference type="EMBL" id="JATAAI010000037">
        <property type="protein sequence ID" value="KAK1734706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XVM9"/>
    <dbReference type="Proteomes" id="UP001224775">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043829">
        <property type="term" value="F:tRNA-specific adenosine-37 deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002466">
        <property type="entry name" value="A_deamin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46516">
        <property type="entry name" value="TRNA-SPECIFIC ADENOSINE DEAMINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46516:SF1">
        <property type="entry name" value="TRNA-SPECIFIC ADENOSINE DEAMINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02137">
        <property type="entry name" value="A_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00552">
        <property type="entry name" value="ADEAMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50141">
        <property type="entry name" value="A_DEAMIN_EDITASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="A to I editase" evidence="13">
        <location>
            <begin position="107"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00040502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1734706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001224775"/>
        </source>
    </evidence>
    <sequence length="507" mass="55418" checksum="E25340A81DB96F8D" modified="2024-05-29" version="1">MTATLSDQIAQCALNHYHTVLPSNGGKPQSTEWTVYAAIVACRQHPNDSNDQDELWVVSCATGSKCTSIRPVVSSLPTQTSQKQGRKRPHSDLSSEVDDDKICACYDGMVLKDSHAETLARRGLMAVLWDEVENLLQNEPTPRPLLEAISASESRQQFQLRNDTSLHMYISDNPCGDATIYRIKKSSSNSTDQPETSINFTGAKIILSDSNGQSVVKQDESISSTLTCSSAADTVITVGREDVQQLGALRLKSSRSNIPSHLRSMSMSCSDKLVRWGVLGLGGALLSMYIPNPIVLSSICVSKDPRAVDGNADLGQLDALRRAIKERIECALMSIAEKEKGWNVNPPEVAVVTDVFENSKSSSEFRHDTKMNALAHNTPNNKGRVKKESVCGMSINWHQTIVQEAANAEVTIGATGLKRGKKPKCPTDVINTASRLSRYHFALRCGKRDPVSSKTETDGHYSSYRKYKQITSTHLLTRVATLALSGGGPLAGWVRSSSQDDFELPHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XVU2</accession>
    <name>A0AAD8XVU2_9STRA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Deaminated glutathione amidase</fullName>
            <ecNumber evidence="3">3.5.1.128</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">QTG54_014929</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Skeletonema marinoi</name>
        <dbReference type="NCBI Taxonomy" id="267567"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Stramenopiles</taxon>
            <taxon>Ochrophyta</taxon>
            <taxon>Bacillariophyta</taxon>
            <taxon>Coscinodiscophyceae</taxon>
            <taxon>Thalassiosirophycidae</taxon>
            <taxon>Thalassiosirales</taxon>
            <taxon>Skeletonemataceae</taxon>
            <taxon>Skeletonema</taxon>
            <taxon>Skeletonema marinoi-dohrnii complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2023-06" db="EMBL/GenBank/DDBJ databases">
            <title>Survivors Of The Sea: Transcriptome response of Skeletonema marinoi to long-term dormancy.</title>
            <authorList>
                <person name="Pinder M.I.M."/>
  